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Displaying drugs 51 - 75 of 15063 in total
Selpercatinib is a kinase inhibitor with enhanced specificity for RET tyrosine kinase receptors (RTKs) over other RTK classes.[A202055, A202052, L13604] Enhanced RET (Rearranged during transfection) oncogene expression is a hallmark of many cancers. Although multikinase inhibitors, including cabozantinib, ponatinib, sorafenib, sunitinib, and vandetanib, have shown efficacy in RET-driven cancers, their...
Approved
Investigational
Matched Synonyms: … 6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine
Matched Iupac: … 6-{6-[(6-methoxypyridin-3-yl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl}pyridin-3-yl)pyrazolo[1,5-a]pyridine
Matched Description: … Although multikinase inhibitors, including [cabozantinib], [ponatinib], [sorafenib], [sunitinib], and ... Selpercatinib (LOXO-292) and pralsetinib (BLU-667) represent the first generation of specific RET RTK …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Salsalate is a nonsteroidal anti-inflammatory agent for oral administration. Salsalate's mode of action as an anti-inflammatory and antirheumatic agent may be due to inhibition of synthesis and release of prostaglandins. The usefulness of salicylic acid, the active in vivo product of salsalate, in the treatment of arthritic disorders has been...
Approved
Matched Synonyms: … Disalicylic acid ... o-Salicylsalicylic acid ... Salicylsalicylic acid
Matched Iupac: … 2-(2-hydroxybenzoyloxy)benzoic acid
Matched Description: … synthesis and release of prostaglandins. ... Salsalate's mode of action as an anti-inflammatory and antirheumatic agent may be due to inhibition of ... A significant portion of the parent compound is absorbed unchanged and undergoes rapid esterase hydrolysis …
Matched Categories: … Salicylic Acid and Derivatives …
Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as...
Approved
Nutraceutical
Matched Synonyms: … Lysine acid ... (S)-2,6-diaminohexanoic acid ... L-2,6-Diaminocaproic acid
Matched Iupac: … (2S)-2,6-diaminohexanoic acid
Matched Description: … This amino acid is an essential amino acid, which means that humans cannot synthesize it. ... Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. ... Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. …
Matched Mixtures name: … Champs Multivitamin Plus Folic Acid & Lysine (Orange Flavour) Chewable Tablet ... Aminosyn II and Dextrose ... Aminosyn II and Dextrose …
Matched Salts name: … Lysine hydrochloride
Matched Categories: … arginine and lysine ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Blood Substitutes and Perfusion Solutions …
An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.
Approved
Matched Synonyms: … Carboxyphosphonic acid ... Phosphonoformic acid ... Phosphonomethanoic acid
Matched Iupac: … phosphonoformic acid
Matched Description: … Foscarnet also shows activity against human herpes viruses and HIV. …
Matched Categories: … Phosphonic Acid Derivatives ... Nucleic Acid Synthesis Inhibitors …
Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.
Approved
Matched Synonyms: … 2-(p-bromo-α-(2-dimethylaminoethyl)benzyl)pyridine
Matched Description: … Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria. …
Matched Mixtures name: … Brompheniramine Maleate, Pseudoephedrine Hydrochloride and Dextromethorphan Hydrobromide ... Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide ... Brompheniramine Maleate, Pseudoephedrine Hydrochloride and Dextromethorphan Hydrobromide …
A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
Approved
Nutraceutical
Vet approved
Matched Synonyms: … Aminoacetic acid ... Aminoethanoic acid
Matched Iupac: … 2-aminoacetic acid
Matched Description: … A non-essential amino acid. ... It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Travasol Amino Acid Inj 8.5% …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Blood Substitutes and Perfusion Solutions …
Potassium carbonate (K2CO3) is a white salt, soluble in water (insoluble in ethanol) which forms a strongly alkaline solution. It can be made as the product of potassium hydroxide's absorbent reaction with carbon dioxide. It presents a large capacity to absorb moisture.
Approved
Matched Synonyms: … Carbonic acid, dipotassium salt …
Matched Mixtures name: … Vit C W Calc-mag and Potass Powder ... Buffered Vitamin C Powder With Ca Mg and K …
Matched Categories: … Carbonic Acid
Matched Products: … Moonstar Face and Body Mist …
Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation for the treatment of cutaneous T cell lymphoma (CTCL), a type of skin cancer, to be used when the disease persists, gets worse, or comes back during or after treatment with other medicines. It is the first...
Approved
Investigational
Matched Synonyms: … Suberanilohydroxamic acid ... Suberoylanilide hydroxamic acid ... Octanedioic acid hydroxyamide phenylamide …
Matched Description: … Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV.
Approved
Investigational
Matched Synonyms: … polystyrenesulfonic acid ... Polystyrene sulfonic acid ... poly(styrene-4-sulfonic acid) …
Matched Description: … It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among ... It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as cimetidine and famotidine. This drug helps to prevent and treat gastric-acid associated conditions, including ulcers, because of its ability to decrease gastric acid secretion.[A176759,L10818] Ranitidine is often referred to as...
Approved
Withdrawn
Matched Description: … associated conditions and is therefore widely used in GERD and other gastric-acid related conditions ... This drug helps to prevent and treat gastric-acid associated conditions, including ulcers, because of ... its ability to decrease gastric acid secretion. …
Matched Salts name: … Ranitidine hydrochloride
Matched Categories: … Alimentary Tract and Metabolism ... Acid Reducers ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … Berkley and Jensen Acid Reducer ... Ranitidine Hydrochloride ... Up and Up Acid Reducer Non Prescription Strength …
Approved
Nutraceutical
Matched Synonyms: … Ascorbic acid nicotinamide complex ... Nicotinamide-ascorbic acid complex …
Matched Iupac: … (5R)-5-(1,2-dihydroxyethyl)-3,4-dihydroxy-2,5-dihydrofuran-2-one; pyridine-3-carboxamide …
Matched Mixtures name: … Stress B Complex With C and E Tab ... Stress B Complex With C, E and Iron Tab ... Stress B Complex With C,e, Zinc and Copper …
Matched Categories: … Vitamin C and analogues …
Mepenzolate is a post-ganglionic parasympathetic inhibitor. It decreases gastric acid and pepsin secretion and suppresses spontaneous contractions of the colon. Mepenzolate diminishes gastric acid and pepsin secretion. Mepenzolate also suppresses spontaneous contractions of the colon. Pharmacologically, it is a post-ganglionic parasympathetic inhibitor. It has not been shown to be effective...
Approved
Matched Synonyms: … Mepenzolic acid
Matched Description: … Mepenzolate diminishes gastric acid and pepsin secretion. ... It decreases gastric acid and pepsin secretion and suppresses spontaneous contractions of the colon. …
Matched Categories: … Alimentary Tract and Metabolism …
An essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins.
Approved
Nutraceutical
Matched Synonyms: … 2-Amino-3-hydroxybutyric acid ... L-2-Amino-3-hydroxybutyric acid ... L-α-amino-β-hydroxybutyric acid
Matched Iupac: … (2S,3R)-2-amino-3-hydroxybutanoic acid
Matched Description: … It is found in eggs, milk, gelatin, and other proteins. ... An essential amino acid occurring naturally in the L-form, which is the active form. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Travasol Amino Acid Inj 8.5% …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Approved
Nutraceutical
Matched Synonyms: … L-ascorbic acid, zinc salt ... (-)-ascorbic acid, zinc salt ... L-ascorbic acid, zinc salt (2:1) …
Matched Categories: … Vitamin C and analogues ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Synonyms: … Sodium acid carbonate ... Carbonic acid monosodium salt …
Matched Description: … powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and
Matched Mixtures name: … Up and Up Antacid and Pain Relief ... PEG-3350 and Electrolytes ... HalfLytely and Bisacodyl …
Matched Categories: … Carbonic Acid ... Gastric Acid Lowering Agents ... Antacids and Adsorbents ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Arm and Hammer Baking Soda …
Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Synonyms: … 4-amino-10-methylfolic acid ... 4-amino-N(10)-methylpteroylglutamic acid ... N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Matched Iupac: … -[(4-{[(4-amino-2-imino-2,3-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid
Matched Description: … Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and ... inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and
Matched Categories: … Folic Acid Analogues ... Folic Acid Antagonists ... Antineoplastic and Immunomodulating Agents ... Nucleic Acid Synthesis Inhibitors …
Pralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma . Pralatrexate was developed in response due to the inferior responses of patients using the standard therapy for their B-cells counterparts. Compared to methotrexate, pralatrexate has better accumulation in cancer cells. Pralatrexate is designed to have...
Approved
Investigational
Matched Synonyms: … N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid ... (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid ... (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid
Matched Iupac: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid
Matched Description: … lung cancer, breast cancer, and bladder cancer. ... higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and ... [L37674] It is also being studied for other types of lymphoma and solid malignancy such as non-small-cell …
Matched Categories: … Folic Acid Analogues ... Folic Acid Antagonists ... Antineoplastic and Immunomodulating Agents …
Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne.[Label] It was most widely marketed under the brand name Accutane, which has since been discontinued. Isotretinoin is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the...
Approved
Matched Synonyms: … 13-cis-retinoic acid ... Neovitamin A acid ... 13-cis-Vitamin A acid
Matched Iupac: … (2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
Matched Description: … [L6574] Isotretinoin is associated with major risks in pregnancy and is therefore only available under …
Matched Categories: … Skin and Mucous Membrane Agents …
Fenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and Reugast. Fenbufen acts by...
Approved
Matched Synonyms: … 3-(4-Phenylbenzoyl)propionic acid ... 4-(4-Biphenylyl)-4-oxobutyric acid ... 3-(4-Biphenylylcarbonyl)propionic acid
Matched Iupac: … 4-{[1,1'-biphenyl]-4-yl}-4-oxobutanoic acid
Matched Description: … It can also be used to relieve backaches, sprains, and fractures. ... anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and ... Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.
Approved
Investigational
Matched Synonyms: … 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid ... 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ... 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
Matched Iupac: … 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
Matched Description: … [A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration …
Matched Mixtures name: … Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone …
Matched Salts name: … Ciprofloxacin hydrochloride
Matched Categories: … ciprofloxacin and tinidazole ... ciprofloxacin and ornidazole ... ciprofloxacin and metronidazole ... Ophthalmological and Otological Preparations ... Drug-Related Side Effects and Adverse Reactions …
Matched Products: … Ciprofloxacin and Dextrose ... Ciprofloxacin hydrochloride ... Ciprofloxacin Hydrochloride
Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.
Approved
Investigational
Matched Synonyms: … 4-aminobenzoic acid ethyl ester …
Matched Description: … Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and
Matched Mixtures name: … Up and up vagicaine ... Sore Throat and Cough ... BENZOCAINE and RESORCINOL …
Matched Salts name: … Benzocaine hydrochloride
Matched Categories: … Esters of Aminobenzoic Acid ... Antipruritics and Local Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Sting and Bite ... Bite and Sting relief ... Medicaine Sting and Bite …
Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. The compound was first extracted and isolated from plant species Gaultheria procumbens in 1843. It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and...
Approved
Vet approved
Matched Synonyms: … 2-Hydroxybenzoic acid methyl ester …
Matched Description: … It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and liniments. ... It forms a colorless to yellow or reddish liquid and exhibits a characteristic odor and taste of wintergreen ... It is used as a flavoring agent in chewing gums and mints in small concentrations and added as antiseptic …
Matched Mixtures name: … Walgreens Cool and Heat Muscle and Joint Relief ... Up and Up Pain ... Cold and Hot CVS …
Matched Products: … Neuro Max Pain and Muscle Relief Gel ... Dermorub Liniment Muscle and Joint ... Flexitol Foot and Knee Pain Relief …
Dimethyl fumarate is an agent indicated for the treatment of relapsing forms of multiple sclerosis.[A253942,L43752] The mechanism of action of dimethyl fumarate in multiple sclerosis is not well understood. It is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor...
Approved
Investigational
Matched Synonyms: … Fumaric acid, dimethyl ester ... (E)-But-2-enedioic acid dimethyl ester ... trans-Butenedioic acid dimethyl ester …
Matched Description: … agent for multiple sclerosis approved by the FDA, following [fingolimod] and [teriflunomide]. ... [L43752] Dimethyl fumarate is marketed under the brand name Tecfidera, and it was the third oral disease-modifying …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Phenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. Phenol has been used to disinfect skin and to relieve itching. Phenol is also used as an oral analgesic or anesthetic in products...
Approved
Experimental
Matched Synonyms: … Carbolic acid ... Phenic Acid ... Phenylic acid
Matched Description: … Phenol is an antiseptic and disinfectant. ... Phenol has been used to disinfect skin and to relieve itching. ... It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly …
Matched Mixtures name: … Major Camphor and Phenol ... Poison Oak and Ivy ... CAMPHOR (SYNTHETIC) and PHENOL …
Matched Categories: … Phenol and Derivatives ... Antiseptics and Disinfectants …
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Synonyms: … 4-Amino-3-(4-chlorophenyl)butyric acid ... DL-4-Amino-3-p-chlorophenylbutanoic acid ... beta-(Aminomethyl)-p-chlorohydrocinnamic acid
Matched Iupac: … 4-amino-3-(4-chlorophenyl)butanoic acid
Matched Description: … Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. ... [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the ... [L39429] Baclofen was investigated for use in alcohol dependence and withdrawal; however, evidence …
Matched Salts name: … Baclofen hydrochloride
Matched Categories: … Amino Acids, Peptides, and Proteins ... gamma-Aminobutyric Acid-ergic Agonist …
Displaying drugs 51 - 75 of 15063 in total