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Displaying drugs 126 - 150 of 10530 in total
Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in...
Approved
Investigational
Matched Synonyms: … p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide …
Matched Iupac: … 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide …
Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, and dimethylaminoisopropanol used as an antiviral drug.
Approved
Matched Synonyms: … Inosine-2-hydroxypropyldimethylammonium 4-acetamidobenzoate (1:3) …
Matched Iupac: … tris((2R)-1-(dimethylamino)propan-2-ol); tris(4-acetamidobenzoic acid); 9-[(2R,3R,4S,5R)-3,4-dihydroxy …
Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. It also stimulates osteoblasts to release factors which stimualtes bone resorption by osteoclasts. As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce labour.
Approved
Matched Synonyms: … (5Z,11α,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid ... (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid ... (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid …
Matched Iupac: … (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]hept-5-enoic acid …
Matched Products: … PROPESS OVUL 10 MG OVUL, 1 ADET …
Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries a risk of agranulocytosis. In biomedical applications, radiolabelled (13C-labeled) aminophenazone has been used in breath tests to measure the cytochrome P-450 metabolic activity in liver function tests. The FDA suspended the use of aminophenazone due to its association...
Approved
Withdrawn
Matched Synonyms: … 1-Phenyl-2,3-dimethyl-4-(dimethylamino)-5-pyrazolone ... 1-Phenyl-2,3-dimethyl-4-dimethylaminopyrazol-5-one ... 2,3-Dimethyl-4-dimethylamino-1-phenyl-5-pyrazolone …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.
Approved
Matched Synonyms: … 1-(p-bromophenyl)-1-(2-pyridyl)-3-dimethylaminopropane ... 3-(4-bromophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Amphetamine, a compound discovered over 100 years ago, is one of the more restricted controlled drugs. It was previously used for a large variety of conditions and this changed until this point where its use is highly restricted. Amphetamine, with the chemical formula alpha-methylphenethylamine, was discovered in 1910 and first...
Approved
Illicit
Investigational
Matched Synonyms: … 1-phenyl-2-aminopropane ... rac-(2R)-1-phenylpropan-2-amine …
Matched Iupac: … 1-phenylpropan-2-amine …
Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring. In vivo, abacavir sulfate dissociates to its free base, abacavir.
Approved
Investigational
Matched Synonyms: … {(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol …
Matched Iupac: … [(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl]methanol …
Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
Approved
Matched Synonyms: … (6R,7R,Z)-3-(acetoxymethyl)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-aza-bicyclo ... -3-(acetoxymethyl)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1- ... (6R,7R)-3-Acetoxymethyl-7-{2-(2-amino-thiazol-4-yl)-2-[(Z)-methoxyimino]-acetylamino}-8-oxo-5-thia-1- …
Matched Iupac: … -3-[(acetyloxy)methyl]-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1- …
Matched Mixtures name: … SEFOTAK 1 G IM ENJEKSİYONLUK TOZ İÇEREN FLAKON, 1 ADET …
Matched Products: … SEFAGEN 1 G IM ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 FLAKON + 1 AMPUL ... TAXEGRAM 1 ... CLATAX 1
Cetrimonium is a quaternary ammonium cation whose salts are used as antiseptics.
Approved
Matched Synonyms: … N,N,N-Trimethyl-1-hexadecanaminium …
Matched Mixtures name: … CLORHEXIDINA AL 4% Y CETRIMIDA AL 1% JABÓN ANTISÉPTICO …
Matched Products: … XORTRIM 1 Cetrimide 1% w/v lotion ... Cetrimide Aqueous Soln 1% ... Resdan Dandruff Treatment Liquid 1% …
An ergot alkaloid with uterine and vascular smooth muscle contractile properties.
Approved
Matched Synonyms: … D-lysergic acid 1-hydroxymethylethylamide ... N-(2-Hydroxy-1-methylethyl)-D-(+)-lysergamide ... 9,10-didehydro-N-(2-hydroxy-1-methylethyl)-6-methylergoline-8β(S)-carboxamide …
Matched Iupac: … 1(16),2,9,12,14-pentaene-4-carboxamide ... (4R,7R)-N-[(2S)-1-hydroxypropan-2-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca- …
Matched Salts cas: … 129-51-1
Matched Categories: … Adrenergic alpha-1 Receptor Agonists …
Conivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin). It was approved in 2004 for hyponatremia (low blood sodium levels) caused by syndrome of inappropriate antidiuretic hormone (SIADH). Conivaptan inhibits both isotypes of the vasopressin receptor (V1a and V2).
Approved
Investigational
Matched Synonyms: … 4'-((4,5-dihydro-2-methylimidazo(4,5-d)(1)benzazepin-6(1H)-yl)carbonyl)-2-biphenylcarboxanilide …
Matched Iupac: … N-(4-{4-methyl-3,5,9-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(14),2(6),3,10,12-pentaene-9-carbonyl}phenyl …
Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones...
Approved
Investigational
Matched Synonyms: … (3S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine ... (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine ... (S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine …
Matched Iupac: … (2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5 …
Matched Categories: … MATE 1 Inhibitors ... MATE 1 Substrates …
Matched Products: … İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... INFUZYON ÇÖZELTİSİ, 1 ADET ... L-OPTİC 5 MG/ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET …
An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Approved
Investigational
Matched Synonyms: … 9-((2-Hydroxy-1-(hydroxymethyl)ethoxy)methyl)guanine ... 2-Amino-9-(2-hydroxy-1-hydroxymethyl-ethoxymethyl)-1,9-dihydro-purin-6-one ... 2-amino-9-(2-hydroxy-1-hydroxymethylethoxymethyl)-6,9-dihydro-1H-6-purinone …
Matched Categories: … MATE 1 Substrates …
Matched Products: … İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ, 1 ADET ... TAMOVIR 500 MG IV INFÜZYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON, 1 ADET ... İnfüzyonluk Çözelti Hazırlamada Kullanılacak Konsantre İçin Toz, 1 ADET …
Mavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart Association (NYHA) class II-III obstructive hypertrophic cardiomyopathy (HCM). It received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used in humans. Mavacamten was also approved...
Approved
Investigational
Matched Synonyms: … 6-(((1S)-1-Phenylethyl)amino)-3-(propan-2-yl)-1,2,3,4 tetrahydropyrimidine-2,4-dione …
Matched Iupac: … 6-{[(1S)-1-phenylethyl]amino}-3-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Synonyms: … 17-cyclopropylmethyl-4,5α-epoxy-7α-((S)-1-hydroxy-1,2,2-trimethylpropyl)-6-methoxy-6,14-endo-ethanomorphinan ... 21-cyclopropyl-7α-[(S)-1-hydroxy-1,2,2-trimethylpropyl]-6,14-endo-ethano-6,7,8,14-tetrahydrooripavine …
Matched Description: … Buprenorphine is commercially available as the brand name product Suboxone which is formulated in a 4:1
Matched Mixtures name: … Bupensan Duo 4 mg/1 mg-Sublingualtabletten ... SUBOXONE 8 MG/2 MG DILALTI TABLET, 28 ADET ... SUBOXONE 2 MG/0,5 MG DILALTI TABLET, 28 ADET …
Matched Products: … Bupensan 1 mg-Sublingualtabletten …
Clomipramine, the 3-chloro analog of imipramine, is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, clomipramine does not affect mood or arousal, but may cause sedation. In depressed individuals,...
Approved
Investigational
Vet approved
Matched Synonyms: … 3-(3-chloro-5H-dibenzo[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine ... 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine …
Matched Iupac: … (3-{14-chloro-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-2-yl}propyl)dimethylamine …
Matched Description: … TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic …
Amprenavir is a protease inhibitor used to treat HIV infection.
Approved
Investigational
Matched Synonyms: … (3S)-Tetrahydro-3-furanyl ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl …
Matched Iupac: … (3S)-oxolan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido]-1-phenylbutan-2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Perampanel is a noncompetitive AMPA glutamate receptor antagonist. It is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures. The FDA label includes an important black-boxed warning...
Approved
Matched Synonyms: … 3-(2-Cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one …
Matched Iupac: … 2-{6'-oxo-1'-phenyl-1',6'-dihydro-[2,3'-bipyridine]-5'-yl}benzonitrile …
Matched Salts cas: … 1571982-04-1
Matched Categories: … Heterocyclic Compounds, 1-Ring …
An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Approved
Matched Synonyms: … (1S,3S)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydronaphthacen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside …
Matched Products: … ZAVEDOS 5 MG FLAKON, 1 ADET ... ZAVEDOS 10 MG FLAKON, 1 ADET ... ZAVEDOS® SOLUCIÓN INYECTABLE 1 MG/ML …
One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
Approved
Investigational
Matched Synonyms: … ]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[2-(2-Amino-thiazol-4-yl)-acetylamino]-3-[1-(2-dimethylamino-ethyl)-1H-tetrazol-5-ylsulfanylmethyl …
Matched Iupac: … -5-yl}sulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[2-(2-amino-1,3-thiazol-4-yl)acetamido]-3-[({1-[2-(dimethylamino)ethyl]-1H-1,2,3,4-tetrazol …
Matched Salts cas: … 66309-69-1
An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Approved
Matched Synonyms: … (1S,3S)-3-GLYCOLOYL-1,2,3,4,6,11-HEXAHYDRO-3,5,12-TRIHYDROXY-10-METHOXY-6,11-DIOXO-1-NAPHTHACENYL 3-AMINO ... -L-ARABINO-HEXOPYRANOSYL)OXY)-7,8,9,10-TETRAHYDRO-6,8,11-TRIHYDROXY-8-(HYDROXYACETYL)-1-METHOXY-, (8S-CIS …
Matched Iupac: … )-10-{[(2R,4S,5R,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1- …
Matched Salts cas: … 56390-09-1
Matched Products: … ANTHRACIN 10MG/5ML IV ENFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET ... ANTHRACIN 50MG/25ML IV ENFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET ... EPİRİTU 20MG/10ML IV/İNTRAVEZİKAL İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET …
Lauric acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations of melting-point depression. Lauric acid is a solid at room temperature but melts easily in boiling water, so liquid lauric acid can be treated with various solutes and used to determine their molecular masses.
Approved
Experimental
Matched Synonyms: … 1-undecanecarboxylic acid ... Undecane-1-carboxylic acid …
Approved
Nutraceutical
Matched Synonyms: … L-ascorbic acid, zinc salt (2:1) …
Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and...
Approved
Matched Synonyms: … Deoxyribonuclease (human clone 18-1 protein moiety) …
Matched Categories: … Recombinant Human Deoxyribonuclease 1
Berdazimer is a polymeric substance consisting of a polysiloxane backbone (Si-O-Si bonds) with covalently bound N-diazeniumdiolate nitric oxide (NO) donors. It releases NO through exposure to proton donors like water, which will degrade the N-diazeniumdiolate entity. Berdazimer was previously investigated as a potential treatment for molluscum contagiosum, a viral cutaneous...
Approved
Matched Synonyms: … Silsesquioxanes, 3-(2-hydroxy-1-methyl-2-nitrosohydrazinyl)propyl 3-(methylamino)propyl, polymers with …
Matched Salts cas: … 1846565-00-1
Displaying drugs 126 - 150 of 10530 in total