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Xaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman primate STEAP1 and CD3.
Investigational
Matched Synonyms: … the prostate 1, STEAP1 metalloreductase) and anti-[Homo sapiens CD3, bispecific, trivalent ... scFv-CH/G1-kappa, anti-[Homo sapiens STEAP1 (STEAP family member 1, six transmembrane epithelial antigen of
Matched Description: … primate STEAP1 and CD3. ... Xaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman …
Experimental
Matched Name: … octyl 3-amino-3-deoxy-2-O-(2,6-dideoxy-alpha-L-lyxo-hexopyranosyl)-beta-D-galactopyranoside …
Matched Iupac: … (2S,3S,4S,6S)-6-{[(2R,3R,4S,5R,6R)-4-amino-5-hydroxy-6-(hydroxymethyl)-2-(octyloxy)oxan-3-yl]oxy}-2-methyloxane …
Levonorgestrel (LNG) is a synthetic progestogen similar to Progesterone used in contraception and hormone therapy.[A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD. Some of these devices...
Approved
Investigational
Matched Synonyms: … 13-Ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one ... 17alpha-Ethynyl-13beta-ethyl-3-oxo-4-estren-17beta-ol ... 17alpha-Ethynyl-17-hydroxy-18-methylestr-4-en-3-one
Matched Iupac: … 1-ethynyl-1-hydroxy-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
Matched Description: … Some of these devices are known as Jaydess, Kyleena, and Mirena. ... progesterone, showing high levels of efficacy and a lack of estrogenic adverse effects when compared ... Levonorgestrel (LNG) is a synthetic progestogen similar to [Progesterone] used in contraception and hormone …
Matched Mixtures name: … Levonorgestrel and Ethinyl Estradiol and Ethinyl Estradiol ... Levonorgestrel and Ethinyl Estradiol and Ethinyl Estradiol ... Levonorgestrel and Ethinyl Estradiol and Ethinyl Estradiol …
Matched Categories: … Sex Hormones and Modulators of the Genital System ... levonorgestrel and estrogen ... levonorgestrel and estrogen ... levonorgestrel and ethinylestradiol ... levonorgestrel and ethinylestradiol …
Matched Products: … ONE-AND-ONE ... Plan B One-Step ... PostDay One-Step …
Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as ritonavir for the effective management of HIV-1 infection. As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006. Darunavir is being...
Approved
Matched Synonyms: … aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-benzylpropyl)((1S,2R,5R)-4,6-dioxabicyclo(3.3.0)oct
Matched Description: … [A191682] Clinical trials are underway and are expected to conclude in August 2020.[L12066] ... inhibitor used with other HIV protease inhibitor drugs as well as [ritonavir] for the effective management of
Matched Categories: … combinations of sulfonamides ... Antivirals used in combination for the treatment of HIV infections ... darunavir and ritonavir ... darunavir and cobicistat ... Genito Urinary System and Sex Hormones …
Matched Products: … Darunavir 600 and 800 mg …
Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders. Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity.
Approved
Vet approved
Matched Iupac: … hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
Matched Description: … Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. ... [A192444] Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity. ... [A192444] It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally …
Matched Mixtures name: … Clotrimazole and Betamethasone Dipropionate ... Clotrimazole and Betamethasone Dipropionate ... Clotrimazole and Betamethasone Dipropionate …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... betamethasone and mydriatics ... betamethasone and antiseptics …
Matched Products: … Betnesol Eye and Ear Drops ... Betnesol Eye and Ear Drops 0.1% ... DIPROSONE OV
Experimental
Matched Name: … ]triazacyclohexadecin-8(9H)-one ... 19-(cyclopropylamino)-4,6,7,15-tetrahydro-5H-16,1-(azenometheno)-10,14-(metheno)pyrazolo[4,3-o][1,3,9 …
Matched Iupac: … 2,8,16,17,19,20-hexaazatetracyclo[12.5.2.1^{3,7}.0^{17,21}]docosa-1(20),3(22),4,6,14(21),15,18-heptaen-9-one
Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.
Approved
Investigational
Nutraceutical
Withdrawn
Matched Synonyms: … 5'-O-Phosphonoadenosine …
Matched Description: … by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and ... Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified ... to the sugar moiety in the 2'-, 3'-, or 5'-position. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
An oligosaccharide antibiotic produced by various streptomyces. [PubChem]
Approved
Investigational
Matched Synonyms: … ]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside ... (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl …
Matched Iupac: … }-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy}-2-(hydroxymethyl)oxane-3,4-diol ... )-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy
Matched Categories: … Alimentary Tract and Metabolism …
A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
Approved
Investigational
Matched Iupac: … 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one
Matched Description: … of the pentose ring. ... It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). ... A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon …
Matched Mixtures name: … Lamivudine and Zidovudine ... Lamivudine and Zidovudine ... Lamivudine and Zidovudine …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections ... lamivudine and abacavir ... stavudine and lamivudine ... zidovudine and lamivudine ... lamivudine and raltegravir …
Matched Products: … Lamivudine and Zidovudine …
Cinolazepam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant activity. It is not approved in Canada or America.
Experimental
Matched Synonyms: … 7-chloro-5-(o-fluorophenyl)-2,3-dihydro-3-hydroxy-2-oxo-1H-1,4-benzodiazepine-1-propionitrile ... 1-(2-cyanoethyl)-7-chloro-3-hydroxy-5-(2'-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one ... 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-3-hydroxy-2-oxo-1H-1,4-benzodiazepine-1-propanenitrile …
Matched Iupac: … 3-[7-chloro-5-(2-fluorophenyl)-3-hydroxy-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-1-yl]propanenitrile …
Matched Description: … It is not approved in Canada or America. ... Cinolazepam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives …
Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis. Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain, or first line as a topical treatment of corticosteroid responsive dermatoses. Triamcinolone is more...
Approved
Vet approved
Matched Iupac: … hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
Matched Description: … Triamcinolone is more commonly seen in the forms triamcinolone hexacetonide, triamcinolone acetonide, and ... or first line as a topical treatment of corticosteroid responsive dermatoses. ... [L8255] Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain,[L8264] …
Matched Mixtures name: … Kenacomb Ont ... Viaderm Kc Ont ... Point Of Care Kit KM …
Matched Categories: … Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... triamcinolone and antiseptics ... triamcinolone and antibiotics ... triamcinolone and antiinfectives …
Matched Products: … Up and Up Nasal Allergy ... Foster and Thrive 24 Hour Nasal Allergy ... Kenalog Ont 0.1% …
Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of...
Approved
Vet approved
Withdrawn
Matched Description: … [L11512] It is one of the most common skin and mucous membrane antiseptic agents in use today. ... [A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two ... due to a significant number of reports concerning chemical and thermal burns associated with the use …
Matched Mixtures name: … Burn O Sol Spray ... ChloraPrep One-Step ... ChloraPrep One-Step …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Biguanides and Amidines ... Alimentary Tract and Metabolism ... Mouthwashes and Gargles ... Antiseptics and Disinfectants …
Matched Products: … Foster and Thrive ... PLAK OUT ... Oro Clear …
A benzodiazepine used to treat various seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop.[FDA Label][L5572,F3763,F3787,F3796] The agent has also been indicated for treating panic disorder.[FDA Label][A175438,L5572,F3763,F3787,F3796] The mechanism of action appears to involve the enhancement of gamma-aminobutyric acid receptor responses.[FDA Label][A175438,A175441,L5572,F3763,F3787,F3796] Since being...
Approved
Illicit
Matched Synonyms: … 5-(o-chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one ... 1,3-dihydro-7-nitro-5-(2-chlorophenyl)-2H-1,4.benzodiazepin-2-one ... 5-(2-chlorophenyl)-7-nitro-1H-benzo[e][1,4]diazepin-2(3H)-one
Matched Iupac: … 5-(2-chlorophenyl)-7-nitro-2,3-dihydro-1H-1,4-benzodiazepin-2-one
Matched Description: … epilepsy, and absence seizures, although tolerance may develop. ... of gamma-aminobutyric acid receptor responses. ... , however, like most benzodiazepines, clonazepam use has also been associated with recreational use and
Matched Categories: … Benzodiazepines and benzodiazepine derivatives …
Ubidecarenone, also called coenzyme Q10, is a 1,4-benzoquinone. From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number of isoprenyl subunits in its tail. It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation. The ubidecarenone is...
Approved
Investigational
Nutraceutical
Matched Description: … of isoprenyl subunits in its tail. ... to treat, cure or prevent any disease. ... From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number …
Matched Mixtures name: … Formula O.C. ... Vitamin E and Coq10 ... Co-q10 and Vitamin E …
Matched Categories: … Enzymes and Coenzymes ... Diet, Food, and Nutrition …
Matched Products: … Coenzyme Q10 With Hawthorn Extract and Citrus Bioflavonoids …
Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow...
Approved
Vet approved
Matched Description: … Oxygen is an element displayed by the symbol O, and atomic number 8. ... Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing ... Higher level of oxygen than ambient air (hyperoxia) can be introduced under normobaric or hyperbaric …
Matched Mixtures name: … Co-NE-O2-N2 Mixture ... Co-HE-O2-N2 Mixture ... Carbon Dioxide and Oxygen Mixture, Compressed, Oxidizing, N.O.S. …
Matched Products: … OSSIGENO FARMA GAS MEDICAL AND TECHNICAL GASES ... Ez-OX ... EZ-Ox
Experimental
Matched Name: … 2',3'-O-{4-[Hydroxy(oxido)-λ5-azanylidene]-2,6-dinitro-2,5-cyclohexadiene-1,1-diyl}adenosine 5'-(tetrahydrogen …
Matched Iupac: … [(3'aR,4'R,6'R,6'aR)-4'-(6-amino-9H-purin-9-yl)-6'-({[hydroxy({[hydroxy(phosphonooxy)phosphoryl]oxy}) ... phosphoryl]oxy}methyl)-2,6-dinitro-3'a,4',6',6'a-tetrahydrospiro[cyclohexane-1,2'-furo[3,4-d][1,3]dioxole …
A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation.
Approved
Matched Synonyms: … O-methylxanthotoxol ... 9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one
Matched Iupac: … 9-methoxy-7H-furo[3,2-g]chromen-7-one
Matched Description: … It is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation. ... A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia …
Matched Categories: … Indicators and Reagents ... Compounds used in a research, industrial, or household setting …
Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the...
Approved
Vet approved
Withdrawn
Matched Description: … and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. ... It also binds to some extent to the bacterial 50S ribosomal subunit and may alter the cytoplasmic membrane ... [L43942] Other formulations of tetracycline continue to be used. …
Matched Mixtures name: … Bismuth Subcitrate Potassium, Metronidazole and Tetracycline Hydrochloride ... Bismuth Subcitrate Potassium, Metronidazole, and Tetracycline Hydrochloride …
Matched Categories: … combinations of tetracyclines ... Alimentary Tract and Metabolism ... tetracycline and oleandomycin ... Ophthalmological and Otological Preparations ... lansoprazole, tetracycline and metronidazole …
Matched Products: … Achromycin Ont Oph 1% ... MeaStem First Aid and Antibiotic …
Benzonatate is an oral antitussive drug used in the relief and suppression of cough in patients older than ten years of age. Currently, benzonatate is the only non-narcotic antitussive available as a prescription drug. It works to reduce the activity of cough reflex by desensitizing the tissues of the lungs...
Approved
Matched Synonyms: … p-butylaminobenzoic acid ω-O-methylnonaethyleneglycol ester …
Matched Description: … [A189519] It works to reduce the activity of cough reflex by desensitizing the tissues of the lungs and ... Benzonatate is an oral antitussive drug used in the relief and suppression of cough in patients older ... acid class (such as [procaine] and [tetracaine]), benzonatate exhibits anesthetic or numbing action. …
Matched Categories: … Cough and Cold Preparations …
Ketotifen is a benzocycloheptathiophene derivative with potent antihistaminic and mast cell stabilizing properties. It has a similar structure to some other first-generation antihistamines such as cyproheptadine and azatadine. Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis. In the...
Approved
Matched Iupac: … 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.0^{3,7}]tetradeca-1(14),3(7),4,10,12-pentaen-8-one
Matched Description: … available and indicated as an add-on therapy for children with atopic asthma. ... [L32283] In addition, oral ketotifen is used in Mexico and across Europe for the treatment of various ... marketed for the treatment of anaphylaxis. …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Up and Up Eye Itch Relief ... Care One Allergy Eye ... Care One Eye Itch Relief …
Experimental
Matched Name: … (2R,3S,5S)-2-(Hydroxymethyl)-5-[(2-sulfoethyl)carbamoyl]-3-pyrrolidiniumyl 2-acetamido-2-deoxy-4-O-sulfo-beta-D-glucopyranoside …
Matched Iupac: … (2R,3S,5S)-3-{[(2R,3R,4R,5S,6R)-3-acetamido-4-hydroxy-6-(hydroxymethyl)-5-(sulfooxy)oxan-2-yl]oxy}-2- …
Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone...
Approved
Illicit
Investigational
Matched Synonyms: … 4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one ... 4,5α-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one ... 4,5alpha-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
Matched Iupac: … }]octadeca-7(18),8,10-trien-14-one ... (1S,5R,13R,17S)-17-hydroxy-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18 …
Matched Description: … [A178696] It is currently indicated as an immediate release product for moderate to severe pain and as ... [Label] The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950. …
Matched Mixtures name: … Oxycodone and Aspirin ... Oxycodone and Aspirin ... Oxycodone and Acetaminophen …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome ... oxycodone and naloxone ... oxycodone and ibuprofen ... oxycodone and naltrexone …
Matched Products: … Oxynorm 10mg/ml Solution for Injection or Infusion ... Sterile Solution for Injection or Infusion 10mg/ml ... OXICODONA 10 MG/ML SOLUCIÓN PARA INYECCIÓN O INFUSIÓN …
Investigational
Matched Synonyms: … Uridine, 5'-o-(5-amino-5-deoxy-.beta. ... 5-{[(5-amino-3,3-dihydroxyoxolan-2-yl)oxy][5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan ... -d-ribofuranosyl)-5'-c-((2s)-5-(((4-butylphenyl)amino)carbonyl)-2,3,4,7-tetrahydro-1,4-dimethyl-3-oxo
Matched Iupac: … (2S)-2-[(S)-{[(2S,3R,4S,5R)-5-(aminomethyl)-3,4-dihydroxyoxolan-2-yl]oxy}[(2S,3S,4R,5R)-5-(2,4-dioxo- ... 1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-N-(4-butylphenyl)-1,4-dimethyl-3-oxo
Matched Categories: … Drugs for Treatment of Tuberculosis …
The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson].[A229833,A229838] Adenosine...
Approved
Investigational
Matched Description: … L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole] and ... [L31998] Adenosine was granted FDA approval on 30 October 1989.[L31978] ... The structure of adenosine was first described in 1931,[A229823] though the vasodilating effects were …
Matched Mixtures name: … Too im Cell ALL IN ONE ... Seamoms Tamanu Oil Mist ... D-one By Tamdoan Bb Light …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … misoli Power Snail and Collagen Hydrog el Mask Pack ... rootree Treetherapy Rejuvenating Eye and Neck Treatment ... Oozoo Face Serum Alpha One Nutrient …
DHEA sulfate is the major steroid of the fetal adrenal. DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of ACTH and prolactin. DHEA-S is elevated with hyperprolactinemia.
Investigational
Matched Synonyms: … 3-O-Sulfodehydroepiandrosterone ... (3-beta)-3-(Sulfooxy)androst-5-en-17-one ... Androst-5-en-17-on-3beta-yl sulfuric acid …
Matched Iupac: … [(3aS,3bR,7S,9aR,9bS,11aS)-9a,11a-dimethyl-1-oxo-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta …
Matched Description: … DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of ... ACTH and prolactin. ... DHEA sulfate is the major steroid of the fetal adrenal. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Displaying drugs 651 - 675 of 700 in total