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Displaying drugs 126 - 150 of 4745 in total

Ascorbic acid

A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic...
Approved
Nutraceutical
Matched Mixtures name: … Maxi 6 Liq ... ซีตา 500+บี6 ... DAYCOLD-HOT 500/10/15/100 MG SAŞE,6 SAŞE …
Matched Products: … FORDRAY 250 MG VAJİNAL TABLET, 6 ADET ... Liqui C-300 ... Bio C 300 Tab …

Chlorphenesin

Approved
Experimental

Oxytocin

Sir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906.[A229008,A228593,A229108] Like all other neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 residues.[A229008,A228593] In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent...
Approved
Vet approved
Matched Description: … neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 …
Matched Products: … ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 6 ADET …

Riluzole

A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis. Riluzole is marketed as Rilutek by Sanofi.
Approved
Investigational
Matched Iupac: … 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine …
Matched Products: … TEGLUTIK 5 MG/ ML ORAL SÜSPANSIYON, 300 ML …

Isometheptene

Isometheptene is a sympathomimetic drug that causes vasoconstriction. It is used for treating migraines and tension headaches.
Approved
Matched Iupac: … methyl(6-methylhept-5-en-2-yl)amine …
Matched Mixtures name: … DIPIRONA 300 MG + ISOMETEPTENO MUCATO 30 MG + CAFEINA 30 MG ... DIPIRONA 300 MG + ISOMETEPTENO 50 MG + CAFEINA 30 MG GOTAS ... DIPIRONA 300 MG + ISOMETEPTENO MUCATO 30 MG + CAFEINA 30 MG …

Crizotinib

Crizotinib is a tyrosine kinase receptor inhibitor used for the treatment of anaplastic lymphoma kinase (ALK) or ROS1-positive non-small cell lung cancer (NSCLC) tumors, as well as ALK-positive anaplastic large cell lymphoma (ALCL) and inflammatory myofibroblastic tumor (IMT). By targeting the echinoderm microtubule-associated protein-like 4 (EML4)-ALK fusion protein, crizotinib offers...
Approved
Investigational

Fondaparinux

Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule. It is structurally similar to polymeric glycosaminoglycan heparin and heparan sulfate (HS) when they are cleaved into monomeric units. The monomeric sequence in heparin and HS...
Approved
Investigational
Matched Iupac: … )-6-[(sulfooxy)methyl]oxan-2-yl]oxy}-4-hydroxy-6-{[(2R,3S,4R,5R,6S)-4-hydroxy-6-methoxy-5-(sulfoamino ... (2R,3S,4S,5R,6R)-3-{[(2R,3R,4R,5R,6R)-5-{[(2R,3R,4R,5S,6S)-6-carboxy-5-{[(2R,3R,4R,5S,6R)-4,5-dihydroxy ... -3-(sulfoamino)-6-[(sulfooxy)methyl]oxan-2-yl]oxy}-3,4-dihydroxyoxan-2-yl]oxy}-3-(sulfoamino)-4-(sulfooxy …
Matched Description: … Fondaparinux potentiates the neutralizing action of ATIII on activated Factor X 300-fold. …

Dutasteride

Dutasteride is an oral synthetic 4-azasteroid commonly marketed under the trade name Avodart. It is a novel dual 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and irreversible manner. Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary hormonal...
Approved
Investigational

Nitrofurantoin

Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections.[L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. This drug is more resistant to the development of bacterial resistance because it acts...
Approved
Vet approved
Matched Description: … [A179830] Nitrofurantoin was granted FDA approval on 6 February 1953.[L6895] …
Matched Products: … PIYELOSEPTYL 25 MG/5 ML ORAL SUSPANSIYON, 300 ML …

Flunarizine

Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
Approved
Matched Salts cas: … 30484-77-6 …

Cimetidine

A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Products: … ดูโอดิน 300 ... Tagamet 300 ... ยาฉีด พอนดาร์เมทท์ - 300 …

Rufinamide

Rufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy. Clinical trials suggest its efficacy in the treatment of partial seizures.
Approved

Phenoxyethanol

Phenoxyethanol is a colorless liquid with a pleasant odor. It is a glycol ether used as a perfume fixative, insect repellent, antiseptic, solvent, preservative, and also as an anesthetic in fish aquaculture. Phenoxyethanol is an ether alcohol with aromatic properties. It is both naturally found and manufactured synthetically. Demonstrating antimicrobial...
Approved
Matched Mixtures name: … Manugel 85 …

Chlorambucil

A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Approved
Matched Description: … mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85 …

Oxygen

Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow...
Approved
Vet approved
Matched Products: … Oxygen/Nitrogen 15/85 …

Mirvetuximab soravtansine

Mirvetuximab soravtansine-gynx (IMGN853) is an antibody-drug conjugate (ADC) formed by a monoclonal antibody (M9346A) that targets folate receptor alpha (FRα), covalently joined by a cleavable disulfide linker to the genotoxic compound DM4 (also known as soravtansine or ravtansine).[A254392,L43967] DM4 is conjugated to the antibody with a drug-to-antibody ratio of 3.5:1....
Approved
Investigational

Tioconazole

Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus". Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In...
Approved
Matched Mixtures name: … TRİVAG 300 MG / 200 MG/ 100 MG OVÜL, 3 ADET ... GYNOMAX XL 200 MG/ 300 MG/100 MG VAJINAL OVÜL, 3 ADET …

Sodium iodide

Sodium iodide is a water-soluble ionic compound with a crystal lattice. Sodium iodide is a source of iodine and can be administered as a supplement for total parenteral nutrition but is more commonly used in veterinary medicine. Radiolabelled compound, DB09293, is used as a diagnostic tool to evaluate thyroid function...
Approved
Matched Mixtures name: … .-6 Concentrated ... Micro+6 Concentrate ... Sclerodine 6 Injection …

Vitamin A

Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in...
Approved
Nutraceutical
Vet approved
Matched Mixtures name: … Maxi 6 Liq ... Feminex 300 Tab …

Human immunoglobulin G

Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ion exchange chromatography. IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population....
Approved
Investigational
Matched Products: … INTRAGAM P INJECTION 6% w/v ... HYQVİA 30 G/300 ML SC KULLANIM İÇİN İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... KIOVIG 30 GR/300 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET …

Dapsone

A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with pyrimethamine in the treatment of...
Approved
Investigational
Matched Mixtures name: … Dapsone 6% / Niacinamide 4% ... Dapsone 6% / Niacinamide 2% / Tretinoin 0.025% ... Dapsone 6% / Niacinamide 2% / Spironolactone 5% …

Azithromycin

Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration . It was initially approved by the FDA in 1991 . It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used instead of other macrolides for...
Approved
Matched Iupac: … (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl ... 13-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,6,8,10,12,14-heptamethyl-1-oxa-6- …
Matched Description: … The results were positive, all patients taking the combination were virologically cured within 6 days …
Matched Products: … TREMAC 250 MG KAPSÜL, 6 KAPSÜL ... ZİTROGEN 250 MG KAPSÜL , 6 ADET ... AZITRO 250 MG FILM KAPLI TABLET, 6 ADET …

Omaveloxolone

Omaveloxolone (RTA-408) is a semisynthetic oleanane triterpenoid with antioxidant and anti-inflammatory properties.[A257534,A257539] Omaveloxolone acts as an activator of nuclear factor (erythroid-derived 2)-like 2 (Nrf2), a transcription factor that mitigates oxidative stress. In patients with Friedreich's ataxia, a genetic disease involving mitochondrial dysfunction, the Nrf2 pathway is impaired, and Nrf2 activity...
Approved
Investigational

Troglitazone

Troglitazone was withdrawn in 2000 due to risk of hepatotoxicity. It was superseded by pioglitazone and rosiglitazone.
Approved
Investigational
Withdrawn
Matched Iupac: … 5-({4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-1-benzopyran-2-yl)methoxy]phenyl}methyl)-1,3-thiazolidine …

Olanzapine

Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent. The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to drug-drug interactions. Olanzapine very closely resembles clozapine and only differs by...
Approved
Investigational
Matched Mixtures name: … TARGET 6 MG /25 MG KAPSUL, 90 ADET ... TARGET 6 MG /50 MG KAPSUL, 90 ADET ... TARGET 6 MG /25 MG KAPSUL, 30 ADET …
Displaying drugs 126 - 150 of 4745 in total