Gastric Ulcer (GU)

Also known as: Gastric ulceration / Gastric Ulcers / Gastric Ulcer / Stomach Ulcer / Ulcer gastric / Ulcus ventriculi / Ulcer stomach / GU

DrugDrug NameDrug Description
DB01050IbuprofenAn NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.
DB00929MisoprostolA prostaglandin E1 analogue used to reduce the risk of NSAID-induced gastric ulcers.
DB00585NizatidineAn H2 receptor antagonist used to treat GERD and a variety of ulcers.
DB00338OmeprazoleA proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection.
DB00213PantoprazoleA proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid.
DB01129RabeprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
DB00863RanitidineA histamine H2 antagonist used to treat duodenal ulcers, Zollinger-Ellison syndrome, gastric ulcers, GERD, and erosive esophagitis.
DB00364SucralfateA gastro-duodenal protective agent used in the treatment of gastric and duodenal ulcers and to prevent duodenal ulcer recurrence.
DrugDrug NameTargetType
DB01050IbuprofenProstaglandin G/H synthase 1target
DB01050IbuprofenProstaglandin G/H synthase 2target
DB01050IbuprofenCytochrome P450 2C9enzyme
DB01050IbuprofenSerum albumincarrier
DB01050IbuprofenMultidrug resistance-associated protein 4transporter
DB01050IbuprofenMultidrug resistance-associated protein 1transporter
DB01050IbuprofenSolute carrier organic anion transporter family member 1A2transporter
DB01050IbuprofenSolute carrier family 22 member 6transporter
DB01050IbuprofenSolute carrier family 22 member 8transporter
DB01050IbuprofenSolute carrier family 22 member 11transporter
DB01050IbuprofenSolute carrier organic anion transporter family member 2B1transporter
DB01050IbuprofenP-glycoprotein 1transporter
DB01050IbuprofenUDP-glucuronosyltransferase 1-3enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 1-9enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 2B4enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 2B7enzyme
DB01050IbuprofenCytochrome P450 2C8enzyme
DB01050IbuprofenCytochrome P450 2C19enzyme
DB01050IbuprofenApoptosis regulator Bcl-2target
DB01050IbuprofenThrombomodulintarget
DB01050IbuprofenFatty acid-binding protein, intestinaltarget
DB01050IbuprofenPeroxisome proliferator-activated receptor gammatarget
DB01050IbuprofenCystic fibrosis transmembrane conductance regulatortarget
DB01050IbuprofenPeroxisome proliferator-activated receptor alphatarget
DB01050IbuprofenPlatelet glycoprotein Ib alpha chaintarget
DB01050IbuprofenProtein S100-A7target
DB01050IbuprofenAlpha-methylacyl-CoA racemaseenzyme
DB01050IbuprofenCytochrome P450 3A4enzyme
DB00929MisoprostolProstaglandin E2 receptor EP2 subtypetarget
DB00929MisoprostolProstaglandin E2 receptor EP3 subtypetarget
DB00929MisoprostolProstaglandin E2 receptor EP4 subtypetarget
DB00929MisoprostolProstaglandin E2 receptor EP1 subtypetarget
DB00585NizatidineHistamine H2 receptortarget
DB00585NizatidineP-glycoprotein 1transporter
DB00585NizatidineCholinesteraseenzyme
DB00338OmeprazolePotassium-transporting ATPase alpha chain 1target
DB00338OmeprazoleCytochrome P450 2C19enzyme
DB00338OmeprazoleCytochrome P450 3A4enzyme
DB00338OmeprazoleCytochrome P450 2C9enzyme
DB00338OmeprazoleCytochrome P450 1A2enzyme
DB00338OmeprazoleCanalicular multispecific organic anion transporter 2transporter
DB00338OmeprazoleP-glycoprotein 1transporter
DB00338OmeprazoleATP-binding cassette sub-family G member 2transporter
DB00338OmeprazoleCytochrome P450 1A1enzyme
DB00338OmeprazoleCytochrome P450 1B1enzyme
DB00338OmeprazoleCytochrome P450 2C18enzyme
DB00338OmeprazoleCytochrome P450 2C8enzyme
DB00338OmeprazoleCytochrome P450 2D6enzyme
DB00338OmeprazoleAryl hydrocarbon receptortarget
DB00213PantoprazolePotassium-transporting ATPase alpha chain 1target
DB00213PantoprazoleCytochrome P450 2C19enzyme
DB00213PantoprazoleCytochrome P450 3A4enzyme
DB00213PantoprazoleP-glycoprotein 1transporter
DB00213PantoprazoleATP-binding cassette sub-family G member 2transporter
DB00213PantoprazoleSolute carrier family 22 member 8transporter
DB00213PantoprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
DB01129RabeprazolePotassium-transporting ATPase alpha chain 1target
DB01129RabeprazoleCytochrome P450 3A4enzyme
DB01129RabeprazoleCytochrome P450 2C19enzyme
DB01129RabeprazoleATP-binding cassette sub-family G member 2transporter
DB01129RabeprazoleCytochrome P450 1A1enzyme
DB01129RabeprazoleCytochrome P450 1A2enzyme
DB01129RabeprazoleCytochrome P450 2C9enzyme
DB01129RabeprazoleCytochrome P450 2D6enzyme
DB01129RabeprazoleCytochrome P450 2C8enzyme
DB00863RanitidineHistamine H2 receptortarget
DB00863RanitidineCytochrome P450 1A2enzyme
DB00863RanitidineCytochrome P450 2D6enzyme
DB00863RanitidineSolute carrier family 22 member 1transporter
DB00863RanitidineP-glycoprotein 1transporter
DB00863RanitidineSolute carrier family 22 member 8transporter
DB00863RanitidineCytochrome P450 3A4enzyme
DB00863RanitidineAcetylcholinesterasetarget
DB00863RanitidineSolute carrier family 22 member 2transporter
DB00863RanitidineCholinesterasetarget
DB00863RanitidineCholinesteraseenzyme
DB00364SucralfateFibrinogentarget
DB00364SucralfatePepsin A-5target
DB00364SucralfatePro-epidermal growth factortarget
DB00364SucralfateFibroblast growth factor 2target
DrugDrug NamePhaseStatusCount
DB12770Lafutidine1Completed1
DB00338Omeprazole1Completed2
DB00788Naproxen1 / 2Completed1
DB01060Amoxicillin2 / 3Unknown Status1
DB01211Clarithromycin2 / 3Unknown Status1
DB00916Metronidazole2 / 3Unknown Status1
DB01129Rabeprazole2 / 3Unknown Status1
DB00945Acetylsalicylic acid3Completed2
DB01060Amoxicillin3Unknown Status1
DB00482Celecoxib3Completed1
DB01211Clarithromycin3Unknown Status1
DB00586Diclofenac3Terminated1
DB00736Esomeprazole3Completed7
DB00736Esomeprazole3Recruiting1
DB00736Esomeprazole3Terminated1
DB12079Gefarnate3Completed1
DB12079Gefarnate3Terminated1
DB00448Lansoprazole3Completed7
DB00448Lansoprazole3Recruiting1
DB00448Lansoprazole3Terminated1
DB00448Lansoprazole3Unknown Status1
DB00929Misoprostol3Terminated1
DB00788Naproxen3Completed3
DB00788Naproxen3Terminated1
DB00338Omeprazole3Completed3
DB00863Ranitidine3Completed1
DB11656Rebamipide3Completed1
DB11739Vonoprazan3Recruiting1
DB01060Amoxicillin4Completed1
DB04115Berberine4Completed1
DB00736Esomeprazole4Completed2
DB00927Famotidine4Terminated1
DB00614Furazolidone4Completed1
DB00448Lansoprazole4Completed1
DB00338Omeprazole4Completed1
DB00213Pantoprazole4Terminated1
DB01129Rabeprazole4Completed1
DB11656Rebamipide4Completed2
DB00759Tetracycline4Completed1
DB00945Acetylsalicylic acidNot AvailableUnknown Status1
DB00758ClopidogrelNot AvailableUnknown Status1
DB00213PantoprazoleNot AvailableCompleted1
DB01129RabeprazoleNot AvailableUnknown Status1
DB11656RebamipideNot AvailableCompleted1