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Displaying drugs 51 - 75 of 11686 in total
Trimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects. It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI...
Approved
Matched Synonyms: … 2-Dimethylamino-2-phenylbutyl 3,4,5-trimethoxybenzoat …
Matched Iupac: … 2-(dimethylamino)-2-phenylbutyl 3,4,5-trimethoxybenzoate …
Darifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence. Darifenacin blocks M3 muscarinic acetylcholine receptors, which mediate bladder muscle contractions. This block reduces the urgency to urinate and so it should not be used in people with urinary retention. It is unknown if M3 receptor selectivity is clinically...
Approved
Investigational
Matched Synonyms: … (S)-1-(2-(2,3-dihydro-5-benzofuranyl)ethyl)-α,α-diphenyl-3-pyrrolidineacetamide …
Matched Iupac: … 2-[(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-diphenylacetamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … ENABLEX 15 MG ... Darifenacin 15 mg ... DARUCIL® ER 15 MG …
Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor agonists used to treat acute migraine.[A462, L12978] Sumatriptan was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. This led to the development of second-generation triptans, including almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, and zolmitriptan. Triptans...
Approved
Investigational
Matched Synonyms: … 4-[[3-(2-dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-one ... (S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one …
Matched Iupac: … (4S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … MIGTERA 5 MG FİLM TABLET, 2 ADET ... MIGTERA 2.5 MG FİLM TABLET, 2 ADET …
Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy.[L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. In contrast to other PDE5 inhibitors...
Approved
Investigational
Matched Synonyms: … (6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino(1',2':1,6)pyrido(3,4-b ... (6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido( …
Matched Iupac: … (2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … REKFİL 20 MG TABLET, 2 ADET ... LONGIVO 20 MG TABLET, 2 TABLET ... ORCAFIL 10 MG FILM TABLET ,2 ADET …
Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring. In vivo, abacavir sulfate dissociates to its free base, abacavir.
Approved
Investigational
Matched Synonyms: … {(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol …
Matched Iupac: … [(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl]methanol …
Matched Salts cas: … 188062-50-2
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … ZIAGEN ORAL SOLÜSYON 300 MG/15 ML, 240 ML …
Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.
Approved
Matched Synonyms: … 2-(p-bromo-α-(2-dimethylaminoethyl)benzyl)pyridine ... [3-(4-Bromo-phenyl)-3-pyridin-2-yl-propyl]-dimethyl-amine ... 1-(p-bromophenyl)-1-(2-pyridyl)-3-dimethylaminopropane …
Matched Iupac: … [3-(4-bromophenyl)-3-(pyridin-2-yl)propyl]dimethylamine …
Matched Salts cas: … 980-71-2
Matched Mixtures name: … ยาแก้หวัดเด็ก ตรางู สูตร 2
Matched Products: … ฟรอสซี่ ออเร้นจ์ 2
An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Approved
Investigational
Matched Synonyms: … 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-1H-purin-6(9H)-one ... 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-9H-purin-6-ol ... 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-3H-purin-6(9H)-one …
Matched Iupac: … 2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-6,9-dihydro-1H-purin-6-one …
Matched Categories: … MATE 2 Substrates ... Heterocyclic Compounds, 2-Ring …
Diethylamino hydroxybenzoyl hexyl benzoate is a UV filter with high absorption in the UV-A range. Minimizing the overexposure of human skin to ultraviolet radiation that may lead to acute and chronic photodamage, diethylamino hydroxybenzoyl hexyl benzoate is an oil-soluble UV filter that may be incorporated in the oil phase of...
Approved
Matched Synonyms: … Hexyl 2-(4-(diethylamino)-2-hydroxybenzoyl)benzoate …
Matched Iupac: … hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate …
Bronopol, or 2-Bromo-2-nitro-1,3-propanediol, is an organic compound with wide-spectrum antimicrobial properties. First synthesized in 1897, bronopol was primarily used as a preservative for pharmaceuticals and was registered in the United States in 1984 for use in industrial bactericides, slimicides and preservatives . Bronopol is used as a microbicide or microbiostat...
Approved
Matched Synonyms: … 2-Bromo-2-nitropropane-1,3-diol ... 2-Nitro-2-bromo-1,3-propanediol …
Matched Iupac: … 2-bromo-2-nitropropane-1,3-diol …
Matched Description: … Bronopol, or 2-Bromo-2-nitro-1,3-propanediol, is an organic compound with wide-spectrum antimicrobial …
Lofexidine is a non-opioid centrally acting alpha2-adrenergic receptor agonist that was first approved for the treatment of opioid withdrawal in the United Kingdom in 1992. It was first studied for use as an antihypertensive in 1980, but its researched was stopped as it was found less effective for the treatment...
Approved
Investigational
Matched Synonyms: … 2-(alpha-(2,6-Dichlorophenoxy)ethyl)2-imidazoline …
Matched Iupac: … 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole …
Matched Categories: … Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist …
Ceftolozane is a semi-synthetic broad-spectrum fifth generation cephalosporin. It was approved by the FDA in 2014 for use in combination with Tazobactam for the treatment of serious infections, such as intra-abdominal infections and complicated urinary tract infections. The manufacturer of this drug is Cubist Pharmaceuticals. Most recently, in June 2019,...
Approved
Investigational
Matched Synonyms: … ]oct-2-ene-2-carboxylate ... (6R,7R)-3-([3-Amino-4-(2-aminoethylcarbamoylamino)-2-methylpyrazol-1-ium-1-yl]methyl)-7-([(2Z)-2-(5-amino ... -1,2,4-thiadiazol-3-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino)-8-oxo-5-thia-1-azabicyclo[4.2.0 …
Matched Iupac: … 5-amino-2-{[(6R,7R)-7-[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido ... ]-2-carboxylato-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-4-{[(2-aminoethyl)carbamoyl]amino ... }-1-methyl-1H-pyrazol-2-ium …
Matched Salts cas: … 936111-69-2
Matched Categories: … Heterocyclic Compounds, 2-Ring …
An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues. [PubChem]
Approved
Matched Synonyms: … 2-(1'-Azacyclooctyl)ethylguanidine ... (2-(Octahydro-1-azocinyl)ethyl)guanidine ... (2-(hexahydro-1(2h)-azocinyl)ethyl)guanidine …
Matched Iupac: … N''-[2-(azocan-1-yl)ethyl]guanidine …
Matched Salts cas: … 645-43-2
Elacestrant is a non-steroidal small molecule and an estrogen receptor (ER) antagonist.[A256838,L44918] In January 2023, it was approved by the FDA for the treatment of ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer.[L44918,L44948] It received a similar approval in the EU in September 2023. Elacestrant binds to estrogen receptor-alpha (ERα)...
Approved
Investigational
Matched Synonyms: … -2-ol ... (2R)-2-(2-(ethyl-((4-(2-(ethylamino)ethyl)phenyl)methyl)amino)-4-methoxy-phenyl)tetralin-6-ol ... 2-naphthalenol, 6-(2-(ethyl((4-(2-(ethylamino)ethyl)phenyl)methyl)amino)-4-methoxyphenyl)-5,6,7,8-tetrahydro …
Matched Iupac: … -2-ol ... (6R)-6-{2-[ethyl({4-[2-(ethylamino)ethyl]phenyl}methyl)amino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen …
Omacetaxine mepesuccinate (formerly known as HHT or Homoharringtonine), is a cephalotaxine ester and protein synthesis inhibitor with established clinical activity as a single agent in hematological malignancies. Omacetaxine mepesuccinate is synthesized from cephalotaxine, which is an extract from the leaves of the plant, Cephalotaxus species. In October 2005, omacetaxine mepesuccinate...
Approved
Investigational
Matched Synonyms: … 3]benzazepin-1-yl] 4-methyl (2R)-2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate ... CEPHALOTAXINE 4-METHYL (2R)-2-HYDROXY-2-(4-HYDROXY-4-METHYLPENTYL)BUTANEDIOATE (ESTER) ... CEPHALOTAXINE, 4-METHYL (2R)-2-HYDROXY-2-(4-HYDROXY-4-METHYLPENTYL)BUTANEDIOATE (ESTER) …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Fenofibrate is a fibric acid derivative like clofibrate and gemfibrozil. Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.[L8588,L8591] Fenofibrate was granted FDA approval on 31 December 1993.
Approved
Matched Synonyms: … Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate ... Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate ... 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester …
Matched Iupac: … propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate …
One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action.
Approved
Matched Synonyms: … 4-(2-aminoethyl)catechol ... 2-(3,4-dihydroxyphenyl)ethylamine ... 4-(2-aminoethyl)pyrocatechol …
Matched Iupac: … 4-(2-aminoethyl)benzene-1,2-diol …
Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination with metformin (Avandamet) or with glimepiride (Avandaryl). Like other thiazolidinediones, the mechanism of action of rosiglitazone is by activation of the intracellular receptor...
Approved
Investigational
Matched Synonyms: … (±)-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione ... (RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion …
Matched Iupac: … 5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione …
A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. nitrous oxide is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required. (From AMA Drug Evaluations Annual, 1994, p178)
Approved
Vet approved
Matched Synonyms: … 1,1,1-trifluoro-2-bromo-2-chloroethane ... 1,1,1-trifluoro-2-chloro-2-bromoethane ... 2-bromo-2-chloro-1,1,1-trifluoroethane …
Matched Iupac: … 2-bromo-2-chloro-1,1,1-trifluoroethane …
An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated.
Approved
Matched Synonyms: … 2-(2'-hydroxy-3'-propylaminopropoxy)-ω-phenylpropiophenone ... 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone …
Matched Iupac: … 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one …
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Approved
Matched Synonyms: … [4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo …
Matched Iupac: … [4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-3-[(carbamoyloxy)methyl]-7-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo …
Matched Salts cas: … 56238-63-2
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … TOZ ICEREN FLAKON, 1 ADET+2 ML COZUCU AMPUL ... ENJEKSİYONLUK TOZ İÇEREN FLAKON, 2 ML 1 AMPUL, FLAKON, 1 ADET …
A sulfanilamide that is used as an antibacterial agent.
Approved
Vet approved
Matched Synonyms: … 2-Sulfa-4-methylpyrimidine ... 2-(Sulfanilamido)-4-methylpyrimidine ... N-(4-Methyl-2-pyrimidyl)sulfanilamide …
Matched Iupac: … 4-amino-N-(4-methylpyrimidin-2-yl)benzene-1-sulfonamide …
Matched Salts cas: … 127-58-2
Approved
Investigational
Matched Synonyms: … dichromate(2−) ... dichromate ion(2−) …
Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure.[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor...
Approved
Matched Synonyms: … (+-)-1-((alpha-(2-Isopropoxyethoxy)-p-tolyl)oxy)-3-(isopropylamino)-2-propanol ... (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol …
Matched Iupac: … 1-[(propan-2-yl)amino]-3-(4-{[2-(propan-2-yloxy)ethoxy]methyl}phenoxy)propan-2-ol …
Matched Salts cas: … 104344-23-2
Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.[L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. Sumatriptan was granted FDA approval on 28 December 1992.
Approved
Investigational
Matched Synonyms: … (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide ... 3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide ... 3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide …
Matched Iupac: … 1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … SUTRIP 100 MG TABLET, 2 ADET ... İMİGRAN 50 MG FILM KAPLI TABLET, 2 ADET ... İMİGRAN 100 MG FILM KAPLI TABLET, 2 ADET …
Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269,...
Approved
Investigational
Matched International brands: … Dormarex 2
Matched Synonyms: … 2-(benzhydryloxy)-N,N-dimethylethylamine ... 2-diphenylmethoxy-N,N-demthylethanamine ... α-(2-dimethylaminoethoxy)diphenylmethane …
Matched Iupac: … [2-(diphenylmethoxy)ethyl]dimethylamine …
Matched Mixtures name: … DIFESTOL %1.2+%2 JEL ... Adventure Medical Kits 1-2 Person First Aid …
Matched Products: … Benadryl Cream 2% ... FENOTRAL JEL %2, 30 G ... ALLENIK 20 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ, 100 AMPUL …
Displaying drugs 51 - 75 of 11686 in total