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Displaying drugs 26 - 50 of 9246 in total
Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic conjunctivitis.[L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first...
Approved
Matched Synonyms: … 4-(p-Chlorobenzyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1-(2H)-phthalazinone …
Matched Iupac: … 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-1,2-dihydrophthalazin-1-one …
Matched Products: … ALLERGODİL %0,1 BURUN SPREYİ, ÇÖZELTİ, 10 ML ... NAZETİN 0,14 MG/PÜSKÜRTME BURUN SPREYİ, ÇÖZELTİ, 10 ML …
A depressor amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
Approved
Investigational
Matched Synonyms: … 4-imidazoleethylamine ... 1H-Imidazole-4-ethanamine ... 2-(4-imidazolyl)ethylamine …
Matched Iupac: … 2-(1H-imidazol-4-yl)ethan-1-amine …
Matched Products: … อัลเลอร์แว็กซ์เทสต์ น้ำยาควบคุมผลบวก 10 ... Prick Test Histamin LETI Positivkontrolle 10 mg/ml Pricktestlösung ... HAL Allergy Pricktest 10 mg/ml Pricktestlösung zur Positivkontrolle …
Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. Serdolect is developed by the Danish pharmaceutical company H. Lundbeck. It is a phenylindole derivative used in the treatment of schizophrenia. It was first marketed in 1996 in several European countries before being withdrawn two years later because of...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one …
Matched Iupac: … 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one …
Matched Products: … Serdolect 4 mg - Filmtabletten ... SERDOLECT 4 MG FILM KAPLI TABLET, 30 ADET …
Dicoumarol is an oral anticoagulant agent that works by interfering with the metabolism of vitamin K. In addition to its clinical use, it is also used in biochemical experiments as an inhibitor of reductases.
Approved
Matched Synonyms: … 3,3'-methylen-bis(4-hydroxy-cumarin) ... 3,3'-methylene-bis(4-hydroxycoumarine) ... bis(4-hydroxycoumarin-3-yl)methane …
Matched Iupac: … 4-hydroxy-3-[(4-hydroxy-2-oxo-2H-chromen-3-yl)methyl]-2H-chromen-2-one …
Matched Categories: … 4-Hydroxycoumarins …
Rezafungin is an echinocandin antifungal drug.[A258393,L45633] Unlike other echinocandins such as caspofungin and micafungin, rezafungin has long‐acting pharmacokinetics and a high stability that allows for it to have long dosing intervals maintaining high plasma exposure. Rezafungin has a half-life higher than 130 hours and can be administered once a week...
Approved
Investigational
Matched Synonyms: … Echinocandin B, 1-((4R,5R)-4-hydroxy-N2-((4''-(pentyloxy)(1,1':4',1''-terphenyl)-4-yl)carbonyl)-5-(2- ... (trimethylammonio)ethoxy)-l-ornithine)-4-((4S)-4-hydroxy-4-(4-hydroxyphenyl)-l-allothreonine)- …
Matched Iupac: … )ethyl]-5,8,11,17,20,23,25-heptahydroxy-18-[(Z)-[hydroxy({4-[4'-(pentyloxy)-[1,1'-biphenyl]-4-yl]phenyl ... (2-{[(3S,4E,6S,7E,9S,11R,15S,16E,18S,20R,21R,22E,24S,25S,26S)-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl …
Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Approved
Investigational
Matched Synonyms: … 4-pyridinecarbohydrazide ... Pyridine-4-carboxylic acid hydrazide …
Matched Iupac: … pyridine-4-carbohydrazide …
Matched Mixtures name: … AkuriT-4 TABLET ... ริมสตาร์ 4 - FDC ... RIFAMPICIN 75 MG / ISONIAZID 50 MG …
Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of...
Approved
Vet approved
Withdrawn
Matched Synonyms: … N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide …
Matched Iupac: … N-(4-chlorophenyl)-1-{N'-[6-(N-{[N'-(4-chlorophenyl)carbamimidamido]methanimidoyl}amino)hexyl]carbamimidamido …
Matched Description: … [A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two …
Matched Mixtures name: … Noble 75% Alcohol Wipes ... Stanhexidine 4% With Isopropyl Alcohol 4% ... Scrub-stat IV 4% …
Matched Products: … Dyna-Hex 75 ... Cristalmina 10 mg/ml Spray zur Anwendung auf der Haut, Lösung ... Dyna-hex 4
Minaprine is a psychotropic drug which has proved to be effective in the treatment of various depressive states. Like most antidepressants minaprine antagonizes behavioral despair. Minaprine is an amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and weight gain.
Approved
Matched Synonyms: … 4-(2-((4-Methyl-6-phenyl-3-pyridazinyl)amino)ethyl)morpholine ... N-(4-Methyl-6-phenyl-3-pyridazinyl)-4-morpholineethanamine ... 4-Methyl-3-(2-morpholinoethylamino)-6-phenylpyridazin …
Matched Iupac: … 4-methyl-N-[2-(morpholin-4-yl)ethyl]-6-phenylpyridazin-3-amine …
A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with pyrimethamine in the treatment of...
Approved
Investigational
Matched Synonyms: … 4-(4-aminophenylsulfonyl)aniline ... 4-(4-amino-benzenesulfonyl)-phenylamine ... 4-(4-aminophenylsulfonyl)benzenamine …
Matched Iupac: … 4-(4-aminobenzenesulfonyl)aniline …
Matched Mixtures name: … Dapsone 6% / Niacinamide 4% ... Dapsone 8.5% / Niacinamide 4% ... 011504 Dapsone 8.5% / Niacinamide 4% …
Ezogabine (D23129) is a close structural analog of the centrally acting analgesic flupitrine. It is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and is currently being studied in Phase 3 trials as an adjunctive treatment for partial-onset seizures in adult patients with refractory epilepsy....
Approved
Investigational
Matched Synonyms: … ethyl {2-amino-4-[(4-fluorobenzyl)amino]phenyl}carbamate ... N-(2-Amino-4-(4-fluorobenzylamino)-phenyl) carbamic acid ethyl ester ... N-(2-Amino-4-(4-fluorobenzylamino)phenyl)carbamic acid ethyl ester …
Matched Iupac: … ethyl N-(2-amino-4-{[(4-fluorophenyl)methyl]amino}phenyl)carbamate …
Matched Description: … FDA approved in June 10, 2011 under the name of ezogabine. …
Vandetanib is an oral once-daily kinase inhibitor of tumour angiogenesis and tumour cell proliferation with the potential for use in a broad range of tumour types. On April 6 2011, vandetanib was approved by the FDA to treat nonresectable, locally advanced, or metastatic medullary thyroid cancer in adult patients.
Approved
Matched Synonyms: … N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methyl-4-piperidinyl)methoxy)-4-quinazolinamine ... N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine …
Matched Iupac: … N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine …
Hydroxyamphetamine is a derivative of amphetamines. Hydroxyamphetamine is intended mainly as local eye drops for diagnostic purposes. It is indirect sympathomimetic agent which cause dilation of the eye pupil before diagnostic test. Among the minor side effects from its use are: change in color vision, difficulty seeing at night, dry...
Approved
Matched Synonyms: … 4-hydroxyamphetamine ... 4-(2-aminopropyl)phenol ... dl-4-hydroxyamphetamine …
Matched Iupac: … 4-(2-aminopropyl)phenol …
Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
Approved
Matched Synonyms: … 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Iupac: … 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Products: … SEREMIG 10 ... CYMALIUM - 10 ... SIBELIUM-10
Buspirone is a novel anxiolytic agent with a unique structure and a pharmacological profile. Belonging to the azaspirodecanedione drug class, buspirone is a serotonin 5-HT1A receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates, and other sedative/anxiolytic drugs. Unlike many drugs used to treat anxiety, buspirone does...
Approved
Investigational
Matched Synonyms: … 8-(4-(4-(2-Pyrimidinyl)-1-piperizinyl)butyl)-8-azaspiro(4,5)decane-7,9-dione …
Matched Iupac: … 8-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}-8-azaspiro[4.5]decane-7,9-dione …
Matched Products: … Buspirone-10 ... แอนซัยโอแลน (10) ... Riva-buspirone 10 mg …
Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. Hydrocortisone was granted FDA approval on 5 August 1952.
Approved
Vet approved
Matched Synonyms: … 4-pregnen-11β,17α,21-triol-3,20-dione ... (11β)-11,17,21-trihydroxypregn-4-ene-3,20-dione ... 11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione …
Matched Mixtures name: … Oto End 10 ... Activir Duo 50 mg/g + 10 mg/g Creme ... Clindamycin 1% / Hydrocortisone 2.5% / Niacinamide 4% …
Matched Products: … GENISONE 10 ... Cortizone 10 ... LIMICORT®-10
Overactive bladder (OAB) is a common condition negatively impacting the lives of millions of patients worldwide. Due to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social embarrassment and a poor quality of life.[A185996,A185999] Oxybutynin, also marketed as Ditropan XL, is an anticholinergic medication used for...
Approved
Investigational
Matched Synonyms: … 4-Diethylamino-2-butinyl alpha-cyclohexylmandelat ... 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate ... 4-(Diethylamino)-2-butynyl alpha-phenylcyclohexaneglycolic acid ester …
Matched Iupac: … 4-(diethylamino)but-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate …
Matched Products: … MUTUM CR® 10 MG ... LYRINELTABLETAS DE 10 MG ... DITRO 10 MG TABLETAS DE LIBERACION CONTROLADA …
Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Synonyms: … -D-GLUCOPYRANOSYL-(1->4))-N(SUP 1)-(4-AMINO-2-HYDROXY-1-OXOBUTYL)-2-DEOXY-, (S)- ... -D-GLUCOPYRANOSYL-(1->4)-O-(6-AMINO-6-DEOXY-.ALPHA. ... -D-GLUCOPYRANOSYL-(1->6))-N(SUP 3)-(4-AMINO-L-2-HYDROXYBUTYRYL)-2-DEOXY-L-STREPTAMINE …
Matched Iupac: … (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl) ... oxan-2-yl]oxy}-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl …
Matched Products: … RYOFEL 1000 MG/4 ML I.M./I.V. ENJEKSİYONLUK ÇÖZELTİ, 10 ADET ... AMIKACINA 1G/4 ML ... RYOFEL 1000 MG/4 ML I.M./I.V. ENJEKSİYONLUK ÇÖZELTİ, 1 ADET …
Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline...
Approved
Investigational
Matched Synonyms: … (3S-trans)-3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine ... (−)-(3S,4R)-4-(p-fluorophenyl)-3-((3,4-(methylenedioxy)phenoxy)methyl)piperidine …
Matched Iupac: … (3S,4R)-3-[(2H-1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine …
Matched Products: … Paroxetine-10 ... PAROXETIN-NEURAX 10 MG ... PAROXETINE TABLETS 10 MG "MEIJI" …
Approved
Experimental
Matched Synonyms: … 2-Phenyl-4-chromone ... 2-Phenyl-4-benzopyron ... 2-Phenylbenzopyran-4-one …
Matched Iupac: … 2-phenyl-4H-chromen-4-one …
Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor B. Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and subsequently C5 convertase. This is...
Approved
Investigational
Matched Synonyms: … 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl) benzoic acid ... BENZOIC ACID, 4-((2S,4S)-4-ETHOXY-1-((5-METHOXY-7-METHYL-1H-INDOL-4-YL)METHYL)-2-PIPERIDINYL)- …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as ritonavir for the effective management of HIV-1 infection. As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006. Darunavir is being...
Approved
Matched Synonyms: … (3R,3aS,6aR)-tetrahydro-2H-furo[2,3-b]furan-3-yl (2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy ... (3R,3aS,6aR)-tetrahydro-2H-furo[2,3-b]furan-3-yl (2S,3R)-4-(4-amino-N-neopentylphenylsulfonamido)-3-hydroxy ... [(S)-3-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-2-hydroxy-1-((R)-phenylmethyl)-propyl]-carbamic acid …
Matched Iupac: … (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido …
Matched Products: … Darunavir Sandoz 75 mg – Filmtabletten ... Darunavir Accord 75 mg Filmtabletten ... PREZISTA ® TABLETAS RECUBIERTASDE 75 MG …
Piperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China . Its use declined in the 1980's as piperaquine resistant strains of Plasmodium falciparum appeared and artemisinin derivatives became available. It has come back into use in combination with the artemisinin derivative DB11638 as part of...
Approved
Experimental
Investigational
Matched Synonyms: … 1,3-bis[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propane …
Matched Iupac: … 7-chloro-4-(4-{3-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propyl}piperazin-1-yl)quinoline …
Matched Salts cas: … 911061-10-4
Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension. Early research into the use of pindolol found it had chronotropic effects, and so further investigation focused on the treatment of arrhythmia. Research into pindolol's use in the treatment of hypertension began in the early 1970s....
Approved
Investigational
Matched Synonyms: … 1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol ... 4-(2-hydroxy-3-isopropylaminopropoxy)-indole ... 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)-propan-2-ol …
Matched Iupac: … 1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol …
Matched Products: … Pindolol-10 Tab 10mg …
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Synonyms: … 3-fluoro-4-phenylhydratropic acid ... 2-(2-fluorobiphenyl-4-yl)propanoic acid ... (±)-2-fluoro-α-methyl-4-biphenylacetic acid …
Matched Iupac: … 2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid …
Nomifensine, formerly marketed as Merital capsules, was associated with an increased incidence of hemolytic anemia. The approved application holder removed Merital capsules from the market on January 23, 1986. FDA published a notice of its determination that Merital capsules were removed from the market for safety reasons (see the Federal...
Approved
Withdrawn
Matched Synonyms: … 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine ... 8-Amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline …
Matched Iupac: … 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine …
Matched Salts cas: … 32795-47-4
Displaying drugs 26 - 50 of 9246 in total