Terpenes
- Name
- Terpenes
- Accession Number
- DBCAT000366
- Description
A class of compounds composed of repeating 5-carbon units of HEMITERPENES.
- Drugs
Drug Drug Description Menadione The primary known function of vitamin K is to assist in the normal clotting of blood, but it may also play a role in normal bone calcification. Acitretin An oral retinoid used in the treatment of severe psoriasis. Dronabinol A synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy. Nabilone A synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy. Alitretinoin A vitamin A derivative used to treat Kaposi's sarcoma and used off label to treat chronic hand eczema and psoriasis. Adenosine A medication used in myocardial perfusion scintigraphy. Mecamylamine A nicotine antagonist used to treat moderate to severe essential hypertension and uncomplicated malignant hypertension. Tretinoin A vitamin A derivative used to treat acne vulgaris, certain types of promyelocytic leukemia, and fine wrinkles. Etretinate For the treatment of severe psoriasis in adults. Isotretinoin A retinoid used to treat severe recalcitrant acne. Phylloquinone A fat soluble vitamin used to treat hemorrhagic conditions in infants and coumarin overdoses. Paclitaxel A taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer. Docetaxel A taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer. Fencamfamin For the the treatment of depressive fatigue in convalescence and other debilitated states as well as in the treatment of depressive day-time fatigue, lack of concentration and lethargy. Camphor A compound used topically to help relieve pain and also as a topical antiseptic. May also be used in vaporizers to help suppress coughing. This medication should not be swallowed. Dimethylallyl Diphosphate Not Available Carbenoxolone An agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise the drug is... Carboxyatractyloside Not Available Farnesol A colorless liquid extracted from oils of plants such as citronella, neroli, cyclamen, and tuberose. It is an intermediate step in the biological synthesis of cholesterol from mevalonic acid in... Thymol An essential oil found in various over-the-counter antibacterial and antifungal products. Geranyl Diphosphate Not Available Colforsin Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities;... Fumagillin Not Available 4-Oxoretinol Not Available Thiocamphor Not Available Arotinoid acid Arotinoid acid is a retinoic acid analog which acts as a selective RAR agonist. Peridinin Not Available Violaxanthin Not Available Norcamphor Not Available Lanosterol Not Available Eucalyptol A common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion. Ovalicin Not Available Camphane Not Available Farnesyl thiopyrophosphate Not Available ISOPENTENYL PYROPHOSPHATE Not Available Huperzine A Investigated for use/treatment in alzheimer's disease. Permethrin An insecticide used to prevent infestation with Sarcoptes scabiei (scabies). Ingenol mebutate A topical agent used for the treatment of actinic keratosis. Cannabinor Investigated for use/treatment in pain (acute or chronic). Fenretinide Investigated for use/treatment in macular degeneration. Ecabet For the treatment of reflux oesophagitis and peptic ulcer disease. Paclitaxel docosahexaenoic acid Investigated for use/treatment in breast cancer, colorectal cancer, gastric cancer, kidney cancer, lung cancer, pancreatic cancer, prostate cancer, and skin cancer. IRX-5183 Investigated for use/treatment in adverse effects (chemotherapy) and blood (blood forming organ disorders, unspecified). Andrographolide Investigated for use/treatment in ulcerative colitis. Irofulven Investigated for use/treatment in brain cancer, breast cancer, endometrial cancer, liver cancer, lung cancer, ovarian cancer, pancreatic cancer, pediatric indications, prostate cancer, and sarcoma. AI-850 Investigated for use/treatment in breast cancer and solid tumors. Transcrocetinate Investigated for use/treatment in cancer/tumors (unspecified), hemorrhage, hypoxia, respiratory failure, and strokes. Bardoxolone methyl Investigated for use/treatment in lymphoma (unspecified), multiple myeloma, and solid tumors. Paclitaxel trevatide Investigated for use/treatment in brain cancer. Cenisertib Investigated for use/treatment in solid tumors, leukemia (myeloid), myelodysplastic syndrome, and cancer/tumors (unspecified). Dexanabinol Investigated for use/treatment in traumatic brain injuries and neurologic disorders. Deramciclane Investigated for use/treatment in anxiety disorders. Resiniferatoxin Investigated for use/treatment in interstitial cystitis and urinary incontinence. Astaxanthin Investigated for use/treatment in eye disorders/infections, cancer/tumors (unspecified), and asthma. Bevirimat Investigated for use/treatment in HIV infection. Artemether An antimalarial agent used in combination with lumefantrine for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum. Ginkgolide A Ginkgolide A is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inflammatory and... ginkgolide-C Not Available ginkgolide-J Not Available Ginsenoside C Not Available Ginsenoside Rb1 Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). Ginsenosides have been the target of research, as they are viewed as... Ginsenoside Rg1 Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). Ginsenosides have been the target of research, as they are viewed as... Beta carotene A vitamin A precursor found in various nutritional supplements and health products. Cabazitaxel An antineoplastic agent used for the treatment of hormone-refractory metastatic prostate cancer previously treated with a docetaxel-containing treatment regimen. 3-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acid Not Available Farnesyl diphosphate Not Available Gibberellic acid Not Available Gibberellin A4 Not Available Geranylgeranyl diphosphate Not Available ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID Not Available Ro 12-7310 Not Available Blinatumomab An antineoplastic antibody used to treat Philadelphia chromosome-negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL). Cannabidiol An active cannabinoid used as an adjunctive treatment for the management of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome and symptomatic relief of moderate to severe neuropathic pain or other painful conditions, like cancer. Artesunate Artesunate is an artemesinin derivative indicated for the initial treatment of severe malaria. Isosorbide A vasodilator used for the prevention and treatment of angina pectoris due to coronary artery disease. Ecamsule A sunscreen agent found in sunscreens that absorbs UV rays. Pyrethrum extract A chrysanthemum flower extract used to treat head, pubic, and body lice. Zeaxanthin Zeaxanthin is a most common carotenoid alcohols found in nature that is involved in the xanthophyll cycle. As a coexistent isomer of lutein, zeaxanthin is synthesized in plants and some... Enzacamene An ingredient used in sunscreen to block UVB radiation. Lycopene An ingredient found in a variety of supplements and vitamins. Borneol Not Annotated Squalane Not Annotated Squalene Squalene is originally obtained from shark liver oil. It is a natural 30-carbon isoprenoid compound and intermediate metabolite in the synthesis of cholesterol. It is not susceptible to lipid peroxidation... Tiamulin Tiamulin is a pleuromutilin antibiotic drug that is used in veterinary medicine particularly for pigs and poultry. Artenimol For the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with DB13941. Ortataxel Ortataxel has been used in trials studying the treatment of Lymphoma, Lung Cancer, Glioblastoma, and Kidney Cancer. Crocin Crocin has been investigated for the treatment of Hyperglycemia, Metabolic Syndrome, Hypertriglyceridemia, and Hypercholesterolemia. Tesetaxel Tesetaxel has been used in trials studying the treatment of Cancer, Melanoma, Prostate Cancer, Gastric Carcinoma, and Advanced Melanoma, among others. Triptolide Triptolide has been used in trials studying the treatment of HIV, Crohn's Disease, Intestinal Diseases, Gastrointestinal Diseases, and Digestive System Diseases, among others. Gefarnate Gefarnate has been investigated for the treatment and prevention of Stomach Ulcer, Duodenal Ulcer, and Cardio-cerebrovascular Disease. Zuretinol acetate Zuretinol acetate has been used in trials studying the treatment of Impaired Dark Adaptation, RP (Retinitis Pigmentosa), Retinitis Pigmentosa (RP), and LCA (Leber Congenital Amaurosis). Menatetrenone Menatetrenone has been used in trials studying the treatment of Diabetes, Osteoporosis, Prediabetic State, and Hepatocellular Carcinoma. Ajulemic acid Ajulemic acid has been used in trials studying the treatment of Cystic Fibrosis, Dermatomyositis, and Diffuse Cutaneous Systemic Sclerosis. Salvinorin A Salvinorin A has been investigated for the basic science of Pharmaceutical Preparations. Milataxel Milataxel has been used in trials studying the treatment of Mesothelioma. Diazepinomicin Diazepinomicin has been used in trials studying the treatment of Glioblastoma Multiforme. It is a proprietary first-in-class small molecule with the potential to treat multiple solid tumours like the well... Steviolbioside Steviolbioside has been used in trials studying the treatment of HIV-1 Infection. MK-3118 SCY-078 has been used in trials studying the treatment of Mycoses, Candidemia, Candidiasis, Invasive, and Vulvovaginal Candidiasis. Omaveloxolone Omaveloxolone has been used in trials studying the treatment of Relapsed, Refractory Melanoma and Metastatic or Incurable Non-small Cell Lung Cancer. BMS-188797 BMS-188797 has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific. Lupeol Lupeol has been investigated for the treatment of Acne. BMS-184476 BMS-184476 has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific. Beloranib Beloranib has been used in trials studying the treatment of Obesity, Over-weight, Type 2 Diabetes, Craniopharyngioma, and Hypothalamic Injury, among others. Salirasib Salirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung. Larotaxel Larotaxel has been used in trials studying the treatment of Cancer, Metastases, Breast Cancer, Breast Neoplasms, and Pancreatic Neoplasms, among others. Gossypol Gossypol has been used in trials studying the treatment of Non-small Cell Lung Cancer. Parthenolide Parthenolide has been used in trials studying the diagnostic of Allergic Contact Dermatitis. Menaquinone 7 Menaquinone 7 is under investigation in clinical trial NCT00402974 (The Effect of Vitamin K Supplementation on Osteocalcin Carboxylation in Healthy Children). Enoxolone Enoxolone (glycyrrhetic acid) has been investigated for the basic science of Apparent Mineralocorticoid Excess (AME). Artemisinin Artemisinin has been used in trials studying the treatment of Schizophrenia, Malaria, Falciparum, and Plasmodium Falciparum. Levomenol Levomenol has been known to elicit a number of potentially beneficial pharmacological effects, including anti-irritant, anti-inflammatory, and anti-microbial actions. Bisabolol is also demonstrated to enhance the percutaneous absorption of certain... Terpin hydrate An expectorant used to treat bronchitis, pneumonia, bronchiectasis, COPD, and infectious or inflammatory diseases of the upper respiratory tract. Guaiazulen Not Annotated Motretinide Not Annotated Deltamethrin Not Annotated Acetoxolone Not Annotated Xibornol Not Annotated Phenothrin Not Annotated Cypermethrin Not Annotated Bioallethrin Bioallethrin was used for lice and scabies infestation. Other pyrethroids are now used in place of bioallethrin. Glycyrrhizic acid Glycyrrhizic acid is widely applied in foods as a natural sweetener. As a therapeutic agent, is has been used in a vast variety of formulations as it is reported to... Tetramethrin Not Annotated Paclitaxel poliglumex Not Annotated Cyfluthrin Not Annotated Artemotil Artemotil, also known as β-arteether, is a semi-synthetic derivative of artemisinin and a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria... Nabiximols In Canada, Sativex has received a Notice of Compliance (NOC) for use as an as adjunctive treatment for symptomatic relief of spasticity in patients with multiple sclerosis (MS) who have... Madecassic acid Not Annotated Cannabidivarin Cannabidivarin does not currently have any FDA or Health Canada approved indications, however in October 2017 CBDV was given orphan designation by the European Medicines Agency for use in Rett... Asiatic acid From Centella asiatica and other plants; shows a variety of bioactivities. Asiaticoside Not Annotated 13-cis-12-(3'-Carboxyphenyl)retinoic acid Not Annotated Ginsenosides Dammarane type triterpene saponins based mainly on the aglycones, protopanaxadiol and protopanaxatriol. Centella asiatica Centella asiatica is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Menadiol diphosphate Not Annotated Bornyl acetate Not Annotated Lutein Xanthophylls are taken for nutritional supplementation, and also for treating dietary shortage or imbalance. TNP-470 O-(chloroacetylcarbamoyl)fumagillol (TNP-470) has been used in trials studying the treatment of HIV Infections, Sarcoma, Kaposi, and Pancreatic Neoplasms. Betulinic Acid Betulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome. Cannabigerol A natural product found in Cannabis sativa and Helichrysum species. Cannabichromene A natural product found in Cannabis sativa and Helichrysum species. Cannabivarin A natural product found in Cannabis sativa. Cannabinol Cannabinol (CBN) is a physiologically inactive constituent of Cannabis sativa. Ginsenoside B2 Ginsenoside B2 is under investigation in clinical trial NCT00781534 (A Clinical Trial of Ginseng in Diabetes). Menaquinone 6 Menaquinone 6 is under investigation in clinical trial NCT01194778 (Comparison of Efficacy of Different Dosages Vitamin K2). Bifenthrin Bifenthrin is under investigation in clinical trial NCT01560247 (Percutaneous Recanalization in Ischemic Stroke Management in Europe Observational Registry). Rebaudioside A Rebaudioside A is under investigation in clinical trial NCT03510624 (Acute Effect of Rebaudioside A on Glucose Excursion During an Oral Glucose Tolerance Test in Type 2 Diabetes Mellitus). Norbixin Norbixin is under investigation in clinical trial NCT03820245 (Effect of Short-term Annatto Carotenoids Supplementation on Oxidative Stress Status in Healthy Individuals). Perillyl alcohol Perillyl alcohol is under investigation in clinical trial NCT02704858 (Safety and Efficacy Study in Recurrent Grade IV Glioma). Menaquinone Menaquinone is under investigation in clinical trial NCT01533441 (Vitamin K2 Intervention in Patients With Vitamin K Antagonists). Simotaxel Simotaxel is under investigation in clinical trial NCT00088647 (Study Evaluating MST-997 in Advanced Malignant Solid Tumors). Fucoxanthin Fucoxanthin is under investigation in clinical trial NCT03613740 (Effect of Fucoxanthin on the Components of the Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion). Bexarotene A retinoid drug used for cutaneous manifestations of T-cell lymphoma in patients who have not responded well to previous systemic therapy. Retapamulin A topical antibiotic agent used for the treatment of impetigo caused by methicillin-susceptible Staphylococcus aureus or Streptococcus pyogenes. (4R)-limonene Limonene is common in cosmetic products. As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to... Ingenol disoxate Ingenol disoxate is under investigation in clinical trial NCT02120456 (Safety and Efficacy of Escalating Doses of LEO 43204 Applied Once Daily for Two Consecutive Days on Approximately 250 cm2 on... BMS-955176 BMS-955176 is under investigation in clinical trial NCT02415595 (Dose-finding Study of BMS-955176 to Treat HIV-1 Infected Treatment-naive Adults). Levomenthol An organic compound used to treat mild to moderate muscle and joint pain. Madecassoside Not Annotated alpha-Pinene Not Annotated beta-Pinene Not Annotated Ursolic acid Not Annotated Anhydrovitamin A Not Available N-Ethylretinamide N-Ethylretinamide is the ethylamide of all-trans B-retinoic acid. Vitamin A A vitamin important for retinal function that is used clinically to correct vitamin A deficiency. Islatravir Islatravir is under investigation in clinical trial NCT04233216 (Doravirine/islatravir (DOR/ISL) in Heavily Treatment-experienced (HTE) Participants for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-019)). - Drugs & Drug Targets