DB00162 | Vitamin A | A vitamin important for retinal function that is used clinically to correct vitamin A deficiency. |
DB00170 | Menadione | The primary known function of vitamin K is to assist in the normal clotting of blood, but it may also play a role in normal bone calcification. |
DB00459 | Acitretin | An oral retinoid used in the treatment of severe psoriasis. |
DB00470 | Dronabinol | A synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy. |
DB00486 | Nabilone | A synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy. |
DB00523 | Alitretinoin | A vitamin A derivative used to treat Kaposi's sarcoma and used off label to treat chronic hand eczema and psoriasis. |
DB00640 | Adenosine | A medication used in myocardial perfusion scintigraphy. |
DB00657 | Mecamylamine | A nicotine antagonist used to treat moderate to severe essential hypertension and uncomplicated malignant hypertension. |
DB00755 | Tretinoin | A vitamin A derivative used to treat acne vulgaris, certain types of promyelocytic leukemia, and fine wrinkles. |
DB00926 | Etretinate | For the treatment of severe psoriasis in adults. |
DB00982 | Isotretinoin | A retinoid used to treat severe recalcitrant acne. |
DB01022 | Phylloquinone | A fat soluble vitamin used to treat hemorrhagic conditions in infants and coumarin overdoses. |
DB01229 | Paclitaxel | A taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer. |
DB01248 | Docetaxel | A taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer. |
DB01463 | Fencamfamin | For the the treatment of depressive fatigue in convalescence and other debilitated states as well as in the treatment of depressive day-time fatigue, lack of concentration and lethargy. |
DB01744 | Camphor | A compound used topically to help relieve pain and also as a topical antiseptic. May also be used in vaporizers to help suppress coughing. This medication should not be swallowed. |
DB01785 | Dimethylallyl Diphosphate | Not Available |
DB02329 | Carbenoxolone | An agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise the drug is... |
DB02426 | Carboxyatractyloside | Not Available |
DB02509 | Farnesol | A colorless liquid extracted from oils of plants such as citronella, neroli, cyclamen, and tuberose. It is an intermediate step in the biological synthesis of cholesterol from mevalonic acid in... |
DB02513 | Thymol | An essential oil found in various over-the-counter antibacterial and antifungal products. |
DB02552 | Geranyl Diphosphate | Not Available |
DB02587 | Colforsin | Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities;... |
DB02640 | Fumagillin | Not Available |
DB02699 | 4-Oxoretinol | Not Available |
DB02851 | Thiocamphor | Not Available |
DB02877 | Arotinoid acid | Arotinoid acid is a retinoic acid analog which acts as a selective RAR agonist. |
DB03001 | Peridinin | Not Available |
DB03460 | Violaxanthin | Not Available |
DB03540 | Norcamphor | Not Available |
DB03696 | Lanosterol | Not Available |
DB03852 | Eucalyptol | A common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion. |
DB04324 | Ovalicin | Not Available |
DB04501 | Camphane | Not Available |
DB04695 | Farnesyl thiopyrophosphate | Not Available |
DB04714 | ISOPENTENYL PYROPHOSPHATE | Not Available |
DB04864 | Huperzine A | Investigated for use/treatment in alzheimer's disease. |
DB04930 | Permethrin | An insecticide used to prevent infestation with Sarcoptes scabiei (scabies). |
DB05013 | Ingenol mebutate | A topical agent used for the treatment of actinic keratosis. |
DB05048 | Cannabinor | Investigated for use/treatment in pain (acute or chronic). |
DB05076 | Fenretinide | Investigated for use/treatment in macular degeneration. |
DB05265 | Ecabet | For the treatment of reflux oesophagitis and peptic ulcer disease. |
DB05297 | Paclitaxel docosahexaenoic acid | Investigated for use/treatment in breast cancer, colorectal cancer, gastric cancer, kidney cancer, lung cancer, pancreatic cancer, prostate cancer, and skin cancer. |
DB05653 | IRX-5183 | Investigated for use/treatment in adverse effects (chemotherapy) and blood (blood forming organ disorders, unspecified). |
DB05767 | Andrographolide | Investigated for use/treatment in ulcerative colitis. |
DB05786 | Irofulven | Investigated for use/treatment in brain cancer, breast cancer, endometrial cancer, liver cancer, lung cancer, ovarian cancer, pancreatic cancer, pediatric indications, prostate cancer, and sarcoma. |
DB05842 | AI-850 | Investigated for use/treatment in breast cancer and solid tumors. |
DB05974 | Transcrocetinate | Investigated for use/treatment in cancer/tumors (unspecified), hemorrhage, hypoxia, respiratory failure, and strokes. |
DB05983 | Bardoxolone methyl | Investigated for use/treatment in lymphoma (unspecified), multiple myeloma, and solid tumors. |
DB06171 | Paclitaxel trevatide | Investigated for use/treatment in brain cancer. |
DB06347 | Cenisertib | Investigated for use/treatment in solid tumors, leukemia (myeloid), myelodysplastic syndrome, and cancer/tumors (unspecified). |
DB06444 | Dexanabinol | Investigated for use/treatment in traumatic brain injuries and neurologic disorders. |
DB06512 | Deramciclane | Investigated for use/treatment in anxiety disorders. |
DB06515 | Resiniferatoxin | Investigated for use/treatment in interstitial cystitis and urinary incontinence. |
DB06543 | Astaxanthin | Investigated for use/treatment in eye disorders/infections, cancer/tumors (unspecified), and asthma. |
DB06581 | Bevirimat | Investigated for use/treatment in HIV infection. |
DB06697 | Artemether | An antimalarial agent used in combination with lumefantrine for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum. |
DB06743 | Ginkgolide A | Ginkgolide A is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inflammatory and... |
DB06745 | ginkgolide-C | Not Available |
DB06746 | ginkgolide-J | Not Available |
DB06748 | Ginsenoside C | Not Available |
DB06749 | Ginsenoside Rb1 | Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). Ginsenosides have been the target of research, as they are viewed as... |
DB06750 | Ginsenoside Rg1 | Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). Ginsenosides have been the target of research, as they are viewed as... |
DB06755 | Beta carotene | A vitamin A precursor found in various nutritional supplements and health products. |
DB06772 | Cabazitaxel | An antineoplastic agent used for the treatment of hormone-refractory metastatic prostate cancer previously treated with a docetaxel-containing treatment regimen. |
DB07031 | 3-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acid | Not Available |
DB07780 | Farnesyl diphosphate | Not Available |
DB07814 | Gibberellic acid | Not Available |
DB07815 | GIBBERELLIN A4 | Not Available |
DB07841 | Geranylgeranyl diphosphate | Not Available |
DB07895 | ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID | Not Available |
DB08455 | Ro 12-7310 | Not Available |
DB09052 | Blinatumomab | An antineoplastic antibody used to treat Philadelphia chromosome-negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL). |
DB09061 | Cannabidiol | An active cannabinoid used as an adjunctive treatment for the management of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome and symptomatic relief of moderate to severe neuropathic pain or other painful conditions, like cancer. |
DB09274 | Artesunate | For the treatment of severe malaria caused by Plasmodium falciparum in adults and children |
DB09401 | Isosorbide | A vasodilator used for the prevention and treatment of angina pectoris due to coronary artery disease. |
DB09534 | Ecamsule | A sunscreen agent found in sunscreens that absorbs UV rays. |
DB11087 | Pyrethrum extract | A chrysanthemum flower extract used to treat head, pubic, and body lice. |
DB11176 | Zeaxanthin | Zeaxanthin is a most common carotenoid alcohols found in nature that is involved in the xanthophyll cycle. As a coexistent isomer of lutein, zeaxanthin is synthesized in plants and some... |
DB11219 | Enzacamene | An ingredient used in sunscreen to block UVB radiation. |
DB11231 | Lycopene | An ingredient found in a variety of supplements and vitamins. |
DB11288 | Borneol | Not Annotated |
DB11420 | Squalane | Not Annotated |
DB11460 | Squalene | Squalene is originally obtained from shark liver oil. It is a natural 30-carbon isoprenoid compound and intermediate metabolite in the synthesis of cholesterol. It is not susceptible to lipid peroxidation... |
DB11468 | Tiamulin | Tiamulin is a pleuromutilin antibiotic drug that is used in veterinary medicine particularly for pigs and poultry. |
DB11638 | Artenimol | For the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with DB13941. |
DB11669 | Ortataxel | Ortataxel has been used in trials studying the treatment of Lymphoma, Lung Cancer, Glioblastoma, and Kidney Cancer. |
DB11874 | Crocin | Crocin has been investigated for the treatment of Hyperglycemia, Metabolic Syndrome, Hypertriglyceridemia, and Hypercholesterolemia. |
DB12019 | Tesetaxel | Tesetaxel has been used in trials studying the treatment of Cancer, Melanoma, Prostate Cancer, Gastric Carcinoma, and Advanced Melanoma, among others. |
DB12025 | Triptolide | Triptolide has been used in trials studying the treatment of HIV, Crohn's Disease, Intestinal Diseases, Gastrointestinal Diseases, and Digestive System Diseases, among others. |
DB12079 | Gefarnate | Gefarnate has been investigated for the treatment and prevention of Stomach Ulcer, Duodenal Ulcer, and Cardio-cerebrovascular Disease. |
DB12112 | Zuretinol acetate | Zuretinol acetate has been used in trials studying the treatment of Impaired Dark Adaptation, RP (Retinitis Pigmentosa), Retinitis Pigmentosa (RP), and LCA (Leber Congenital Amaurosis). |
DB12148 | Menatetrenone | Menatetrenone has been used in trials studying the treatment of Diabetes, Osteoporosis, Prediabetic State, and Hepatocellular Carcinoma. |
DB12193 | Ajulemic acid | Ajulemic acid has been used in trials studying the treatment of Cystic Fibrosis, Dermatomyositis, and Diffuse Cutaneous Systemic Sclerosis. |
DB12327 | Salvinorin A | Salvinorin A has been investigated for the basic science of Pharmaceutical Preparations. |
DB12334 | Milataxel | Milataxel has been used in trials studying the treatment of Mesothelioma. |
DB12420 | Diazepinomicin | Diazepinomicin has been used in trials studying the treatment of Glioblastoma Multiforme. It is a proprietary first-in-class small molecule with the potential to treat multiple solid tumours like the well... |
DB12430 | BC-3781 | BC-3781 has been used in trials studying the treatment of Infection and Bacterial Infections. |
DB12434 | Steviolbioside | Steviolbioside has been used in trials studying the treatment of HIV-1 Infection. |
DB12471 | MK-3118 | SCY-078 has been used in trials studying the treatment of Mycoses, Candidemia, Candidiasis, Invasive, and Vulvovaginal Candidiasis. |
DB12513 | Omaveloxolone | Omaveloxolone has been used in trials studying the treatment of Relapsed, Refractory Melanoma and Metastatic or Incurable Non-small Cell Lung Cancer. |
DB12619 | BMS-188797 | BMS-188797 has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific. |
DB12622 | Lupeol | Lupeol has been investigated for the treatment of Acne. |
DB12633 | BMS-184476 | BMS-184476 has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific. |
DB12671 | Beloranib | Beloranib has been used in trials studying the treatment of Obesity, Over-weight, Type 2 Diabetes, Craniopharyngioma, and Hypothalamic Injury, among others. |
DB12681 | Salirasib | Salirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung. |
DB12984 | Larotaxel | Larotaxel has been used in trials studying the treatment of Cancer, Metastases, Breast Cancer, Breast Neoplasms, and Pancreatic Neoplasms, among others. |
DB13044 | Gossypol | Gossypol has been used in trials studying the treatment of Non-small Cell Lung Cancer. |
DB13063 | Parthenolide | Parthenolide has been used in trials studying the diagnostic of Allergic Contact Dermatitis. |
DB13075 | Menaquinone 7 | Menaquinone 7 is under investigation in clinical trial NCT00402974 (The Effect of Vitamin K Supplementation on Osteocalcin Carboxylation in Healthy Children). |
DB13089 | Enoxolone | Enoxolone (glycyrrhetic acid) has been investigated for the basic science of Apparent Mineralocorticoid Excess (AME). |
DB13132 | Artemisinin | Artemisinin has been used in trials studying the treatment of Schizophrenia, Malaria, Falciparum, and Plasmodium Falciparum. |
DB13153 | Levomenol | Levomenol has been known to elicit a number of potentially beneficial pharmacological effects, including anti-irritant, anti-inflammatory, and anti-microbial actions. Bisabolol is also demonstrated to enhance the percutaneous absorption of certain... |
DB13163 | Terpin hydrate | An expectorant used to treat bronchitis, pneumonia, bronchiectasis, COPD, and infectious or inflammatory diseases of the upper respiratory tract. |
DB13329 | Guaiazulen | Not Annotated |
DB13368 | Motretinide | Not Annotated |
DB13600 | Deltamethrin | Not Annotated |
DB13640 | Acetoxolone | Not Annotated |
DB13714 | Xibornol | Not Annotated |
DB13717 | Phenothrin | Not Annotated |
DB13721 | Cypermethrin | Not Annotated |
DB13746 | Bioallethrin | Bioallethrin was used for lice and scabies infestation. Other pyrethroids are now used in place of bioallethrin. |
DB13751 | Glycyrrhizic acid | Glycyrrhizic acid is widely applied in foods as a natural sweetener. As a therapeutic agent, is has been used in a vast variety of formulations as it is reported to... |
DB13752 | Tetramethrin | Not Annotated |
DB13809 | Paclitaxel poliglumex | Not Annotated |
DB13828 | Cyfluthrin | Not Annotated |
DB13851 | Artemotil | Artemotil, also known as β-arteether, is a semi-synthetic derivative of artemisinin and a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria... |
DB14011 | Nabiximols | In Canada, Sativex has received a Notice of Compliance (NOC) for use as an as adjunctive treatment for symptomatic relief of spasticity in patients with multiple sclerosis (MS) who have... |
DB14037 | Madecassic acid | Not Annotated |
DB14050 | Cannabidivarin | Cannabidivarin does not currently have any FDA or Health Canada approved indications, however in October 2017 CBDV was given orphan designation by the European Medicines Agency for use in Rett... |
DB14054 | Asiatic acid | From Centella asiatica and other plants; shows a variety of bioactivities. |
DB14081 | Asiaticoside | Not Annotated |
DB14097 | 13-cis-12-(3'-Carboxyphenyl)retinoic acid | Not Annotated |
DB14152 | Ginsenosides | Dammarane type triterpene saponins based mainly on the aglycones, protopanaxadiol and protopanaxatriol. |
DB14256 | Centella asiatica | Centella asiatica is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. |
DB14650 | Menadiol diphosphate | Not Annotated |
DB14665 | Bornyl acetate | Not Annotated |
DB00137 | Lutein | Xanthophylls are taken for nutritional supplementation, and also for treating dietary shortage or imbalance. |
DB08633 | TNP-470 | O-(chloroacetylcarbamoyl)fumagillol (TNP-470) has been used in trials studying the treatment of HIV Infections, Sarcoma, Kaposi, and Pancreatic Neoplasms. |
DB12480 | Betulinic Acid | Betulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome. |
DB14734 | Cannabigerol | A natural product found in Cannabis sativa and Helichrysum species. |
DB14735 | Cannabichromene | A natural product found in Cannabis sativa and Helichrysum species. |
DB14736 | Cannabivarin | A natural product found in Cannabis sativa. |
DB14737 | Cannabinol | Cannabinol (CBN) is a physiologically inactive constituent of Cannabis sativa. |
DB14815 | Ginsenoside B2 | Ginsenoside B2 is under investigation in clinical trial NCT00781534 (A Clinical Trial of Ginseng in Diabetes). |
DB14936 | Menaquinone 6 | Menaquinone 6 is under investigation in clinical trial NCT01194778 (Comparison of Efficacy of Different Dosages Vitamin K2). |
DB15056 | Bifenthrin | Bifenthrin is under investigation in clinical trial NCT01560247 (Percutaneous Recanalization in Ischemic Stroke Management in Europe Observational Registry). |
DB15136 | Rebaudioside A | Rebaudioside A is under investigation in clinical trial NCT03510624 (Acute Effect of Rebaudioside A on Glucose Excursion During an Oral Glucose Tolerance Test in Type 2 Diabetes Mellitus). |
DB15201 | Norbixin | Norbixin is under investigation in clinical trial NCT03820245 (Effect of Short-term Annatto Carotenoids Supplementation on Oxidative Stress Status in Healthy Individuals). |
DB15289 | Perillyl alcohol | Perillyl alcohol is under investigation in clinical trial NCT02704858 (Safety and Efficacy Study in Recurrent Grade IV Glioma). |
DB15381 | Menaquinone | Menaquinone is under investigation in clinical trial NCT01533441 (Vitamin K2 Intervention in Patients With Vitamin K Antagonists). |
DB15384 | Simotaxel | Simotaxel is under investigation in clinical trial NCT00088647 (Study Evaluating MST-997 in Advanced Malignant Solid Tumors). |
DB15462 | Fucoxanthin | Fucoxanthin is under investigation in clinical trial NCT03613740 (Effect of Fucoxanthin on the Components of the Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion). |
DB00307 | Bexarotene | A retinoid drug used for cutaneous manifestations of T-cell lymphoma in patients who have not responded well to previous systemic therapy. |
DB01256 | Retapamulin | A topical antibiotic agent used for the treatment of impetigo caused by methicillin-susceptible Staphylococcus aureus or Streptococcus pyogenes. |
DB08921 | (4R)-limonene | Limonene is common in cosmetic products. As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to... |
DB15109 | Ingenol disoxate | Ingenol disoxate is under investigation in clinical trial NCT02120456 (Safety and Efficacy of Escalating Doses of LEO 43204 Applied Once Daily for Two Consecutive Days on Approximately 250 cm2 on... |
DB15193 | BMS-955176 | BMS-955176 is under investigation in clinical trial NCT02415595 (Dose-finding Study of BMS-955176 to Treat HIV-1 Infected Treatment-naive Adults). |
DB00825 | Levomenthol | An organic compound used to treat mild to moderate muscle and joint pain. |
DB15532 | Madecassoside | Not Annotated |
DB15573 | alpha-Pinene | Not Annotated |
DB15574 | beta-Pinene | Not Annotated |