Direct Acting Antivirals

DrugDrug NameDrug Description
DB00109EnfuvirtideAn HIV-1 gp41 fusion inhibitor used in patients experiencing HIV-1 replication who are already being treated with other anti-retrovirals.
DB00198OseltamivirA neuraminidase inhibitor used in the prophylaxis and treatment of influenza.
DB00220NelfinavirA viral protease inhibitor used in the treatment of HIV infection.
DB00224IndinavirA protease inhibitor used to treat HIV infection.
DB00238NevirapineA non-nucleoside reverse transcriptase inhibitor used as part of a management regimen for HIV-1 virus infection.
DB00299PenciclovirA topical nucleoside polymerase inhibitor used in the treatment of recurrent herpes labialis.
DB00300Tenofovir disoproxilA nucleotide analog reverse transcriptase inhibitor used in the treatment of Hepatitis B infection and used in the management of HIV-1 infection.
DB00369CidofovirAn antiviral agent used to treat Cytomegalovirus (CMV) retinitis in patients with AIDS.
DB00426FamciclovirA nucleoside analog DNA polymerase inhibitor used for the treatment of recurrent cold sores and genital herpes in healthy patients and patients with HIV, and to manage herpes zoster.
DB00442EntecavirA nucleoside analogue used in the treatment of chronic hepatitis B for patients with active viral replication, histological evidence of active disease, or persistent elevations in liver transaminases.
DB00495ZidovudineA dideoxynucleoside used in the treatment of HIV infection.
DB00503RitonavirAn HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.
DB00529FoscarnetAn antiviral used to treat CMV, HIV, and HSV infections.
DB00558ZanamivirA neuraminidase inhibitor used to treat influenza A and B.
DB00577ValaciclovirAn guanine nucleoside antiviral used to treat herpes exacerbations.
DB00625EfavirenzA non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV.
DB00649StavudineA dideoxynucleoside used in the treatment of HIV infection.
DB00701AmprenavirA protease inhibitor used to treat HIV infection.
DB00705DelavirdineA non-nucleoside reverse transcriptase inhibitor used to treat HIV infection.
DB00709LamivudineA reverse transcriptase inhibitor used to treat HIV and hepatitis B infections.
DB00718Adefovir dipivoxilA nucleotide analog used to treat chronic hepatitis B.
DB00811RibavirinA guanosine nucleoside used to treat some forms of Hepatitis C.
DB00879EmtricitabineA nucleoside reverse transcriptase inhibitor used for the treatment and prophylaxis of HIV.
DB00900DidanosineA reverse transcriptase inhibitor used to treat HIV.
DB00932TipranavirA protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor.
DB00943ZalcitabineA dideoxynucleoside used to treat HIV.
DB01048AbacavirAn antiviral nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals for the treatment of HIV.
DB01072AtazanavirAn antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV.
DB01232SaquinavirAn HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency.
DB01265TelbivudineA thymidine nucleoside analog used for the treatment of chronic hepatitis B with clinical evidence of viral replication or persistent elevations in serum aminotransferases (ALT or AST).
DB01319FosamprenavirAn antiretroviral agent used for the treatment and postexposure prophylaxis of human immunodeficiency virus (HIV-1) infection.
DB01601LopinavirAn HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV).
DB01610ValganciclovirAn antiviral medication used to treat cytomegalovirus (CMV) retinitis in patients diagnosed with acquired immunodeficiency syndrome (AIDS).
DB04835MaravirocA CCR5 co-receptor antagonist used with other antiretroviral medications to treat CCR5-tropic HIV-1 infection.
DB05105PleconarilInvestigated for use/treatment in upper respiratory infection.
DB05521TelaprevirAn NS3/4A viral protease inhibitor used in combination with other antivirals for the curative treatment of chronic Hepatitis C Virus infections.
DB06234MaribavirInvestigated for use/treatment in viral infection, transplantation (organ or tissue), cytomegalovirus (CMV) retinitis, and retinal disorders (unspecified).
DB06414EtravirineA non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents.
DB06683ClevudineInvestigated for use/treatment in hepatitis (viral, B).
DB06817RaltegravirAn antiretroviral agent used for the treatment of HIV infections in conjunction with other antiretrovirals.
DB08864RilpivirineA non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1).
DB08873BoceprevirA hepatitis C virus NS3/4A protease inhibitor used in combination with other medications to treat chronic hepatitis C genotype 1 infection. Boceprevir is not indicated as monotherapy.
DB08930DolutegravirAn antiviral agent used for the treatment of HIV-1 infections in combination with other antiretroviral agents.
DB08934SofosbuvirA direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
DB09027LedipasvirA direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
DB09101ElvitegravirAn antiretroviral agent used in combination with other antiretrovirals for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults.
DB09102DaclatasvirA direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
DB09183DasabuvirA direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
DB09296OmbitasvirA direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections.
DB09297ParitaprevirA direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections.
DB09299Tenofovir alafenamideA nucleoside analog reverse transcriptase inhibitor used for the treatment of chronic hepatitis B virus infection in adults with compensated liver disease.
DB11586AsunaprevirAsunaprevir is indicated in combination with other agents for the treatment of chronic hepatitis C in adult patients with hepatitis C virus genotypes 1 or 4 and compensated liver cirrhosis....
DB11808FaldaprevirFaldaprevir has been investigated for the treatment of Chronic Hepatitis C.
DB13597MoroxydineNot Annotated
DB13609UmifenovirNot Annotated
DB13641MetisazoneNot Annotated
DB00194VidarabineAn antiviral agent used to treat various viral infections.
DB00249IdoxuridineA pyrimidine analog antiviral used for the treatment of viral eye infections, including herpes simplex keratitis.
DB00787AcyclovirA guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster.
DB01004GanciclovirA DNA polymerase inhibitor used to treat cytomegalovirus and herpetic keratitis of the eye.
DB01264DarunavirA HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.
DB06290SimeprevirA direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4.
DB13288TromantadineTromantadine is marketed as Viru-Merz in the Czech Republic . It is an antiviral used in the treatment of herpes zoster and simplex.
DB13997Baloxavir marboxilA polymerase acidic endonuclease inhibitor used to treat uncomplicated influenza.
DB03312BrivudineBrivudine is used in the treatment of herpes zoster. Although not approved in the U.S. or Canada, it is approved in several European countries.
DB06614PeramivirAn intravenous antiviral agent used to treat acute uncomplicated influenza in patients aged 2 years and older who are shown to be symptomatic for no more than two days.
DB11574ElbasvirAn antiviral and NS5A inhibitor used to treat hepatitis C infections.
DB11575GrazoprevirAn antiviral and NS3/4A protease inhibitor used to treat hepatitis C infections.
DB11613VelpatasvirA NS5A inhibitor used to treat chronic hepatitis C infections in patients without cirrhosis or with compensated cirrhosis.
DB11799BictegravirAn integrase inhibitor used to treat HIV infections.
DB12026VoxilaprevirA nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections.
DB12070LetermovirAn antiviral medication used to treat CMV infections and disease in adult CMV-seropositive recipients of an allogeneic hematopoietic stem cell transplant (HSCT).
DB12301DoravirineA non nucleoside reverse transcriptase inhibitor used to treat HIV infections.
DB12698IbalizumabA CD4-specific antibody used to treat HIV infections.
DB13878PibrentasvirA Hepatitis C NS5A inhibitor used to treat Hepatitis C.
DB13879GlecaprevirA Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C.
DrugDrug NameTargetType
DB00109EnfuvirtideEnvelope glycoproteintarget
DB00109EnfuvirtideCytochrome P450 2C19enzyme
DB00109EnfuvirtideCytochrome P450 2E1enzyme
DB00198OseltamivirNeuraminidasetarget
DB00198OseltamivirSialidase-1target
DB00198OseltamivirSialidase-2target
DB00198OseltamivirMultidrug resistance-associated protein 4transporter
DB00198OseltamivirSolute carrier family 15 member 1transporter
DB00198OseltamivirSolute carrier family 22 member 8transporter
DB00198OseltamivirLiver carboxylesterase 1enzyme
DB00220NelfinavirHIV-1 proteasetarget
DB00220NelfinavirCytochrome P450 2C19enzyme
DB00220NelfinavirCytochrome P450 3A4enzyme
DB00220NelfinavirCytochrome P450 2B6enzyme
DB00220NelfinavirCytochrome P450 3A5enzyme
DB00220NelfinavirCytochrome P450 3A7enzyme
DB00220NelfinavirP-glycoprotein 1transporter
DB00220NelfinavirSolute carrier family 22 member 1transporter
DB00220NelfinavirSolute carrier organic anion transporter family member 1A2transporter
DB00220NelfinavirATP-binding cassette sub-family G member 2transporter
DB00220NelfinavirSolute carrier organic anion transporter family member 1B1transporter
DB00220NelfinavirCytochrome P450 2D6enzyme
DB00220NelfinavirSerum albumincarrier
DB00220NelfinavirUDP-glucuronosyltransferase 1-1enzyme
DB00220NelfinavirSolute carrier organic anion transporter family member 1B3transporter
DB00220NelfinavirSolute carrier organic anion transporter family member 2B1transporter
DB00220NelfinavirBile salt export pumptransporter
DB00220NelfinavirCytochrome P450 2C9enzyme
DB00224IndinavirHuman immunodeficiency virus type 1 proteasetarget
DB00224IndinavirCytochrome P450 3A4enzyme
DB00224IndinavirCytochrome P450 3A5enzyme
DB00224IndinavirCytochrome P450 3A7enzyme
DB00224IndinavirP-glycoprotein 1transporter
DB00224IndinavirSolute carrier family 22 member 1transporter
DB00224IndinavirMultidrug resistance-associated protein 1transporter
DB00224IndinavirSolute carrier organic anion transporter family member 1A2transporter
DB00224IndinavirSolute carrier organic anion transporter family member 1B1transporter
DB00224IndinavirCanalicular multispecific organic anion transporter 1transporter
DB00224IndinavirCytochrome P450 2D6enzyme
DB00224IndinavirUDP-glucuronosyltransferase 1-1enzyme
DB00224IndinavirSolute carrier organic anion transporter family member 2B1transporter
DB00224IndinavirBile salt export pumptransporter
DB00238NevirapineCytochrome P450 3A4enzyme
DB00238NevirapineCytochrome P450 2B6enzyme
DB00238NevirapineCytochrome P450 3A5enzyme
DB00238NevirapineCytochrome P450 2C9enzyme
DB00238NevirapineCytochrome P450 2A6enzyme
DB00238NevirapineCytochrome P450 2D6enzyme
DB00238NevirapineReverse transcriptase/RNaseHtarget
DB00238NevirapineSerum albumincarrier
DB00238NevirapineCytochrome P450 1A2enzyme
DB00238NevirapineSolute carrier family 22 member 1transporter
DB00238NevirapineCytochrome P450 3A7enzyme
DB00299PenciclovirDNA polymerase catalytic subunittarget
DB00299PenciclovirThymidine kinasetarget
DB00300Tenofovir disoproxilReverse transcriptase/RNaseHtarget
DB00300Tenofovir disoproxilSolute carrier family 22 member 6transporter
DB00300Tenofovir disoproxilSolute carrier family 22 member 8transporter
DB00300Tenofovir disoproxilMultidrug resistance-associated protein 7transporter
DB00300Tenofovir disoproxilMultidrug resistance-associated protein 4transporter
DB00300Tenofovir disoproxilCanalicular multispecific organic anion transporter 1transporter
DB00300Tenofovir disoproxilAdenylate kinase 2, mitochondrialenzyme
DB00300Tenofovir disoproxilAdenylate kinase 4, mitochondrialenzyme
DB00300Tenofovir disoproxilP-glycoprotein 1transporter
DB00300Tenofovir disoproxilNucleoside diphosphokinaseenzyme
DB00300Tenofovir disoproxilCreatine Kinasesenzyme
DB00300Tenofovir disoproxilDNA polymerase/reverse transcriptasetarget
DB00369CidofovirDNA polymerase catalytic subunittarget
DB00369CidofovirSolute carrier family 22 member 6transporter
DB00369CidofovirThymidine phosphorylaseenzyme
DB00426FamciclovirDNA polymerase catalytic subunittarget
DB00426FamciclovirDNA polymerase catalytic subunittarget
DB00426FamciclovirAldehyde oxidaseenzyme
DB00442EntecavirDNAtarget
DB00495ZidovudineSerum albumincarrier
DB00495ZidovudineCytochrome P450 2A6enzyme
DB00495ZidovudineCytochrome P450 2C9enzyme
DB00495ZidovudineCytochrome P450 3A4enzyme
DB00495ZidovudineReverse transcriptase/RNaseHtarget
DB00495ZidovudineSolute carrier family 22 member 2transporter
DB00495ZidovudineSolute carrier family 22 member 6transporter
DB00495ZidovudineSolute carrier family 22 member 7transporter
DB00495ZidovudineSolute carrier family 22 member 8transporter
DB00495ZidovudineSolute carrier family 22 member 11transporter
DB00495ZidovudineSodium/nucleoside cotransporter 1transporter
DB00495ZidovudineEquilibrative nucleoside transporter 2transporter
DB00495ZidovudineP-glycoprotein 1transporter
DB00495ZidovudineMultidrug resistance-associated protein 4transporter
DB00495ZidovudineMultidrug resistance-associated protein 5transporter
DB00495ZidovudineATP-binding cassette sub-family G member 2transporter
DB00495ZidovudineTelomerase reverse transcriptasetarget
DB00495ZidovudineThymidine kinase, cytosolicenzyme
DB00495ZidovudineUDP-glucuronosyltransferase 2B7enzyme
DB00495ZidovudineUDP-glucuronosyltransferase 1-1enzyme
DB00503RitonavirHuman immunodeficiency virus type 1 proteasetarget
DB00503RitonavirCytochrome P450 2D6enzyme
DB00503RitonavirCytochrome P450 2C9enzyme
DB00503RitonavirCytochrome P450 2C19enzyme
DB00503RitonavirCytochrome P450 2B6enzyme
DB00503RitonavirCytochrome P450 2C8enzyme
DB00503RitonavirP-glycoprotein 1transporter
DB00503RitonavirMultidrug resistance-associated protein 1transporter
DB00503RitonavirCanalicular multispecific organic anion transporter 1transporter
DB00503RitonavirSolute carrier organic anion transporter family member 1A2transporter
DB00503RitonavirATP-binding cassette sub-family G member 2transporter
DB00503RitonavirSolute carrier organic anion transporter family member 1B1transporter
DB00503RitonavirCytochrome P450 1A2enzyme
DB00503RitonavirCytochrome P450 2E1enzyme
DB00503RitonavirNuclear receptor subfamily 1 group I member 2target
DB00503RitonavirSerum albumincarrier
DB00503RitonavirCytochrome P450 3A4enzyme
DB00503RitonavirCytochrome P450 3A5enzyme
DB00503RitonavirCytochrome P450 3A7enzyme
DB00503RitonavirCytochrome P450 3A43enzyme
DB00503RitonavirUDP-glucuronosyltransferase 1-1enzyme
DB00503RitonavirSolute carrier organic anion transporter family member 2B1transporter
DB00503RitonavirBile salt export pumptransporter
DB00529FoscarnetDNA polymerase catalytic subunittarget
DB00529FoscarnetDNA polymerase catalytic subunittarget
DB00529FoscarnetSolute carrier family 22 member 6transporter
DB00529FoscarnetMonocarboxylate transporter 1transporter
DB00558ZanamivirNeuraminidasetarget
DB00558ZanamivirNeuraminidasetarget
DB00558ZanamivirSialidase-2target
DB00577ValaciclovirThymidine kinasetarget
DB00577ValaciclovirDNA polymerase catalytic subunittarget
DB00577ValaciclovirSolute carrier family 15 member 1transporter
DB00577ValaciclovirSolute carrier family 15 member 2transporter
DB00577ValaciclovirSolute carrier family 22 member 8transporter
DB00577ValaciclovirSolute carrier family 22 member 6transporter
DB00577ValaciclovirSodium- and chloride-dependent neutral and basic amino acid transporter B(0+)transporter
DB00577ValaciclovirIleal sodium/bile acid cotransportertransporter
DB00577ValaciclovirGuanylate kinaseenzyme
DB00577ValaciclovirThymidine kinaseenzyme
DB00625EfavirenzCytochrome P450 2B6enzyme
DB00625EfavirenzCytochrome P450 3A4enzyme
DB00625EfavirenzCytochrome P450 2C19enzyme
DB00625EfavirenzCytochrome P450 2C9enzyme
DB00625EfavirenzCytochrome P450 1A2enzyme
DB00625EfavirenzCytochrome P450 2D6enzyme
DB00625EfavirenzReverse transcriptase/RNaseHtarget
DB00625EfavirenzCytochrome P450 2C8enzyme
DB00625EfavirenzSerum albumincarrier
DB00625EfavirenzCytochrome P450 3A5enzyme
DB00625EfavirenzCytochrome P450 3A7enzyme
DB00625EfavirenzUDP-glucuronosyltransferase 1-1enzyme
DB00625EfavirenzBile salt export pumptransporter
DB00625EfavirenzSolute carrier family 22 member 1transporter
DB00649StavudineSolute carrier family 22 member 6transporter
DB00649StavudineReverse transcriptase/RNaseHtarget
DB00649StavudineSodium/nucleoside cotransporter 1transporter
DB00649StavudineSerum albumincarrier
DB00701AmprenavirHuman immunodeficiency virus type 1 proteasetarget
DB00701AmprenavirCytochrome P450 3A4enzyme
DB00701AmprenavirP-glycoprotein 1transporter
DB00701AmprenavirMultidrug resistance-associated protein 1transporter
DB00701AmprenavirCytochrome P450 2B6enzyme
DB00701AmprenavirCytochrome P450 2C19enzyme
DB00701AmprenavirCytochrome P450 2C9enzyme
DB00701AmprenavirCytochrome P450 2D6enzyme
DB00701AmprenavirCytochrome P450 3A5enzyme
DB00701AmprenavirSolute carrier organic anion transporter family member 1B1transporter
DB00705DelavirdineCytochrome P450 3A4enzyme
DB00705DelavirdineCytochrome P450 2C9enzyme
DB00705DelavirdineCytochrome P450 2D6enzyme
DB00705DelavirdineCytochrome P450 3A5enzyme
DB00705DelavirdineCytochrome P450 3A7enzyme
DB00705DelavirdineCytochrome P450 2C19enzyme
DB00705DelavirdineReverse transcriptase/RNaseHtarget
DB00709LamivudineDNAtarget
DB00709LamivudineProtein Ptarget
DB00709LamivudineMultidrug resistance-associated protein 1transporter
DB00709LamivudineSolute carrier family 22 member 6transporter
DB00709LamivudineATP-binding cassette sub-family G member 2transporter
DB00709LamivudineReverse transcriptase/RNaseHtarget
DB00709LamivudineSolute carrier family 22 member 1transporter
DB00709LamivudineSolute carrier family 22 member 2transporter
DB00709LamivudineSolute carrier family 22 member 3transporter
DB00709LamivudineDeoxycytidine kinaseenzyme
DB00709LamivudineUMP-CMP kinaseenzyme
DB00709LamivudinePhosphoglycerate kinase 1enzyme
DB00709LamivudineNucleoside diphosphate kinase Aenzyme
DB00709LamivudineNucleoside diphosphate kinase Benzyme
DB00709LamivudineCholine-phosphate cytidylyltransferase Aenzyme
DB00709LamivudineEthanolamine-phosphate cytidylyltransferaseenzyme
DB00709LamivudineP-glycoprotein 1transporter
DB00709LamivudineMultidrug resistance-associated protein 4transporter
DB00709LamivudineCanalicular multispecific organic anion transporter 2transporter
DB00709LamivudineCanalicular multispecific organic anion transporter 1transporter
DB00709Lamivudine5'(3')-deoxyribonucleotidase, cytosolic typeenzyme
DB00709LamivudineSerum albumincarrier
DB00718Adefovir dipivoxilDNA polymerase/reverse transcriptasetarget
DB00718Adefovir dipivoxilSolute carrier family 22 member 6transporter
DB00718Adefovir dipivoxilMultidrug resistance-associated protein 4transporter
DB00718Adefovir dipivoxilMultidrug resistance-associated protein 5transporter
DB00718Adefovir dipivoxilSolute carrier family 22 member 3transporter
DB00718Adefovir dipivoxilAdenylate kinase 2, mitochondrialenzyme
DB00718Adefovir dipivoxilAdenylate kinase 4, mitochondrialenzyme
DB00718Adefovir dipivoxilNucleoside diphosphate kinase Aenzyme
DB00718Adefovir dipivoxilNucleoside diphosphate kinase Benzyme
DB00811RibavirinRNA-directed RNA polymerase Ltarget
DB00811RibavirinEctonucleotide pyrophosphatase/phosphodiesterase family member 1target
DB00811RibavirinRNA-directed RNA polymerase catalytic subunittarget
DB00811RibavirinCytosolic purine 5'-nucleotidasetarget
DB00811RibavirinInosine-5'-monophosphate dehydrogenase 1target
DB00811RibavirinGenome polyproteintarget
DB00811RibavirinInosine-5'-monophosphate dehydrogenase 2target
DB00811RibavirinAdenosine kinaseenzyme
DB00811RibavirinEquilibrative nucleoside transporter 1transporter
DB00811RibavirinSolute carrier family 28 member 3transporter
DB00879EmtricitabineReverse transcriptase/RNaseHtarget
DB00879EmtricitabineDeoxycytidine kinaseenzyme
DB00879EmtricitabineSerum albumincarrier
DB00879EmtricitabineMultidrug and toxin extrusion protein 1transporter
DB00900DidanosineSolute carrier family 22 member 6transporter
DB00900DidanosinePurine nucleoside phosphorylasetarget
DB00900DidanosineReverse transcriptase/RNaseHtarget
DB00900DidanosineEquilibrative nucleoside transporter 1transporter
DB00900DidanosineEquilibrative nucleoside transporter 2transporter
DB00900DidanosineSerum albumincarrier
DB00932TipranavirHuman immunodeficiency virus type 1 proteasetarget
DB00932TipranavirCytochrome P450 3A4enzyme
DB00932TipranavirCytochrome P450 2D6enzyme
DB00932TipranavirCytochrome P450 2C19enzyme
DB00932TipranavirBile salt export pumptransporter
DB00932TipranavirUDP-glucuronosyltransferase 1-1enzyme
DB00932TipranavirSolute carrier organic anion transporter family member 2B1transporter
DB00932TipranavirSolute carrier organic anion transporter family member 1B1transporter
DB00932TipranavirSolute carrier organic anion transporter family member 1B3transporter
DB00943ZalcitabineDeoxycytidine kinaseenzyme
DB00943ZalcitabineSolute carrier family 22 member 6transporter
DB00943ZalcitabineSolute carrier family 22 member 7transporter
DB00943ZalcitabineReverse transcriptase/RNaseHtarget
DB00943ZalcitabineEquilibrative nucleoside transporter 1transporter
DB00943ZalcitabineEquilibrative nucleoside transporter 2transporter
DB00943ZalcitabineSerum albumincarrier
DB01048AbacavirAlcohol dehydrogenase 6enzyme
DB01048AbacavirUDP-glucuronosyltransferase 1-1enzyme
DB01048AbacavirReverse transcriptase/RNaseHtarget
DB01048AbacavirAdenosine kinaseenzyme
DB01048AbacavirHLA class I histocompatibility antigen, B-57 alpha chaintarget
DB01072AtazanavirHuman immunodeficiency virus type 1 proteasetarget
DB01072AtazanavirCytochrome P450 3A4enzyme
DB01072AtazanavirCytochrome P450 2C9enzyme
DB01072AtazanavirP-glycoprotein 1transporter
DB01072AtazanavirMultidrug resistance-associated protein 1transporter
DB01072AtazanavirSerum albumincarrier
DB01072AtazanavirUDP-glucuronosyltransferase 1-1enzyme
DB01072AtazanavirSolute carrier organic anion transporter family member 1B1transporter
DB01072AtazanavirSolute carrier organic anion transporter family member 1B3transporter
DB01072AtazanavirCytochrome P450 2C8enzyme
DB01072AtazanavirBile salt export pumptransporter
DB01072Atazanaviralpha1-acid glycoproteincarrier
DB01072AtazanavirCytochrome P450 1A2enzyme
DB01072AtazanavirSolute carrier organic anion transporter family member 2B1transporter
DB01232SaquinavirHuman immunodeficiency virus type 1 proteasetarget
DB01232SaquinavirCytochrome P450 3A4enzyme
DB01232SaquinavirCytochrome P450 3A5enzyme
DB01232SaquinavirAlpha-1-acid glycoprotein 1carrier
DB01232SaquinavirSerum albumincarrier
DB01232SaquinavirCytochrome P450 3A7enzyme
DB01232SaquinavirP-glycoprotein 1transporter
DB01232SaquinavirSolute carrier family 22 member 1transporter
DB01232SaquinavirSolute carrier organic anion transporter family member 1A2transporter
DB01232SaquinavirATP-binding cassette sub-family G member 2transporter
DB01232SaquinavirSolute carrier organic anion transporter family member 1B1transporter
DB01232SaquinavirMultidrug resistance-associated protein 1transporter
DB01232SaquinavirCanalicular multispecific organic anion transporter 1transporter
DB01232SaquinavirCytochrome P450 2C8enzyme
DB01232SaquinavirCytochrome P450 2D6enzyme
DB01232SaquinavirSolute carrier organic anion transporter family member 2B1transporter
DB01232SaquinavirBile salt export pumptransporter
DB01265TelbivudineProtein Ptarget
DB01265TelbivudineDNAtarget
DB01319FosamprenavirHuman immunodeficiency virus type 1 proteasetarget
DB01319FosamprenavirCytochrome P450 3A4enzyme
DB01601LopinavirHuman immunodeficiency virus type 1 proteasetarget
DB01601LopinavirCytochrome P450 3A4enzyme
DB01601LopinavirCytochrome P450 2D6enzyme
DB01601LopinavirCytochrome P450 2C19enzyme
DB01601LopinavirP-glycoprotein 1transporter
DB01601LopinavirCytochrome P450 2B6enzyme
DB01601LopinavirCytochrome P450 2C9enzyme
DB01601LopinavirCytochrome P450 2C8enzyme
DB01601LopinavirCytochrome P450 3A Subfamilyenzyme
DB01601LopinavirSolute carrier organic anion transporter family member 1B1transporter
DB01601LopinavirSolute carrier organic anion transporter family member 1B3transporter
DB01601LopinavirBile salt export pumptransporter
DB01610ValganciclovirDNAtarget
DB01610ValganciclovirSolute carrier family 15 member 1transporter
DB01610ValganciclovirSolute carrier family 15 member 2transporter
DB01610ValganciclovirSodium- and chloride-dependent neutral and basic amino acid transporter B(0+)transporter
DB04835MaravirocC-C chemokine receptor type 5target
DB04835MaravirocCytochrome P450 3A4enzyme
DB05105PleconarilPolyproteintarget
DB05521TelaprevirCytochrome P450 3A4enzyme
DB05521TelaprevirNS3/4A proteintarget
DB05521TelaprevirP-glycoprotein 1transporter
DB05521TelaprevirSerum albumincarrier
DB05521TelaprevirAlpha-1-acid glycoprotein 1carrier
DB05521TelaprevirSolute carrier organic anion transporter family member 1B1target
DB05521TelaprevirSolute carrier organic anion transporter family member 2B1target
DB06234MaribavirSerine/threonine protein kinase UL97target
DB06234MaribavirSerine/threonine protein kinase UL97target
DB06414EtravirineCytochrome P450 2C19enzyme
DB06414EtravirineCytochrome P450 2C9enzyme
DB06414EtravirineCytochrome P450 3A4enzyme
DB06414EtravirineGag-Pol polyproteintarget
DB06414EtravirineGag-Pol polyproteintarget
DB06414EtravirineP-glycoprotein 1transporter
DB06414EtravirineMultidrug resistance protein 3transporter
DB06817RaltegravirUDP-glucuronosyltransferase 1-1enzyme
DB06817RaltegravirIntegrasetarget
DB08864RilpivirineCytochrome P450 3A4enzyme
DB08864RilpivirineReverse transcriptase/RNaseHtarget
DB08864RilpivirineNuclear receptor subfamily 1 group I member 2target
DB08864RilpivirineCytochrome P450 2C19enzyme
DB08864RilpivirineCytochrome P450 2B6enzyme
DB08864RilpivirineP-glycoprotein 1transporter
DB08864RilpivirineATP-binding cassette sub-family G member 2transporter
DB08864RilpivirineSolute carrier organic anion transporter family member 1B1transporter
DB08864RilpivirineSolute carrier organic anion transporter family member 1B3transporter
DB08864RilpivirineSerum albumincarrier
DB08864RilpivirineCytochrome P450 2D6enzyme
DB08873BoceprevirCytochrome P450 3A4enzyme
DB08873BoceprevirCytochrome P450 3A5enzyme
DB08873BoceprevirP-glycoprotein 1transporter
DB08873BoceprevirNS3/4A proteintarget
DB08930DolutegravirUDP-glucuronosyltransferase 1-1enzyme
DB08930DolutegravirCytochrome P450 3A Subfamilyenzyme
DB08930DolutegravirIntegrasetarget
DB08930DolutegravirP-glycoprotein 1carrier
DB08930DolutegravirSolute carrier family 22 member 2transporter
DB08930DolutegravirUDP-glucuronosyltransferase 1-3enzyme
DB08930DolutegravirUDP-glucuronosyltransferase 1-9enzyme
DB08930DolutegravirATP-binding cassette sub-family G member 2transporter
DB08930DolutegravirSolute carrier family 22 member 6transporter
DB08930DolutegravirSolute carrier family 22 member 8transporter
DB08934SofosbuvirP-glycoprotein 1transporter
DB08934SofosbuvirATP-binding cassette sub-family G member 2transporter
DB08934SofosbuvirRNA-dependent RNA-polymerasetarget
DB08934SofosbuvirLysosomal protective proteinenzyme
DB08934SofosbuvirCarboxylesteraseenzyme
DB08934SofosbuvirHistidine triad nucleotide-binding protein 1enzyme
DB08934SofosbuvirUMP-CMP kinaseenzyme
DB08934SofosbuvirNucleoside diphosphate kinase Aenzyme
DB09027LedipasvirNonstructural protein 5Atarget
DB09027LedipasvirP-glycoprotein 1transporter
DB09027LedipasvirATP-binding cassette sub-family G member 2transporter
DB09101ElvitegravirIntegrasetarget
DB09101ElvitegravirCytochrome P450 3A4enzyme
DB09101ElvitegravirUDP-glucuronosyltransferase 1-4enzyme
DB09102DaclatasvirNonstructural protein 5Atarget
DB09102DaclatasvirCytochrome P450 3A5enzyme
DB09102DaclatasvirCytochrome P450 3A4enzyme
DB09102DaclatasvirCytochrome P450 3A43enzyme
DB09102DaclatasvirCytochrome P450 3A7enzyme
DB09102DaclatasvirP-glycoprotein 1transporter
DB09102DaclatasvirSolute carrier organic anion transporter family member 1B1transporter
DB09102DaclatasvirSolute carrier organic anion transporter family member 1B3transporter
DB09102DaclatasvirATP-binding cassette sub-family G member 2transporter
DB09183DasabuvirNonstructural protein 5B (NS5B)target
DB09183DasabuvirCytochrome P450 2C8enzyme
DB09183DasabuvirCytochrome P450 3A4enzyme
DB09183DasabuvirCytochrome P450 2D6enzyme
DB09183DasabuvirUDP-glucuronosyltransferase 1-4enzyme
DB09183DasabuvirATP-binding cassette sub-family G member 2transporter
DB09183DasabuvirATP-binding cassette sub-family B member 5transporter
DB09183DasabuvirP-glycoprotein 1transporter
DB09296OmbitasvirNonstructural protein 5Atarget
DB09296OmbitasvirCytochrome P450 2C8enzyme
DB09296OmbitasvirP-glycoprotein 1transporter
DB09296OmbitasvirUDP-glucuronosyltransferase 1-4transporter
DB09296OmbitasvirATP-binding cassette sub-family G member 2transporter
DB09297ParitaprevirNS3/4A proteintarget
DB09297ParitaprevirCytochrome P450 3A4enzyme
DB09297ParitaprevirCytochrome P450 3A5enzyme
DB09297ParitaprevirATP-binding cassette sub-family G member 2transporter
DB09297ParitaprevirP-glycoprotein 1transporter
DB09297ParitaprevirSolute carrier organic anion transporter family member 1B1transporter
DB09297ParitaprevirSolute carrier organic anion transporter family member 1B3transporter
DB09297ParitaprevirUDP-glucuronosyltransferase 1-1enzyme
DB09299Tenofovir alafenamideReverse transcriptase/RNaseHtarget
DB09299Tenofovir alafenamideP-glycoprotein 1transporter
DB09299Tenofovir alafenamideMultidrug resistance-associated protein 4transporter
DB09299Tenofovir alafenamideSolute carrier family 22 member 6transporter
DB09299Tenofovir alafenamideSolute carrier family 22 member 8transporter
DB09299Tenofovir alafenamideLysosomal protective proteinenzyme
DB09299Tenofovir alafenamideLiver carboxylesterase 1enzyme
DB09299Tenofovir alafenamideATP-binding cassette sub-family G member 2transporter
DB09299Tenofovir alafenamideSolute carrier organic anion transporter family member 1B1transporter
DB09299Tenofovir alafenamideSolute carrier organic anion transporter family member 1B3transporter
DB09299Tenofovir alafenamideReverse transcriptasetarget
DB09299Tenofovir alafenamideDNA polymerasetarget
DB09299Tenofovir alafenamideSerum albumincarrier
DB09299Tenofovir alafenamideCytochrome P450 3A4enzyme
DB09299Tenofovir alafenamideAdenylate kinase isoenzyme 1enzyme
DB09299Tenofovir alafenamideAdenylate kinase 2, mitochondrialenzyme
DB09299Tenofovir alafenamideNucleoside diphosphate kinase Aenzyme
DB09299Tenofovir alafenamideNucleoside diphosphate kinase Benzyme
DB11586AsunaprevirGenome polyproteintarget
DB11586AsunaprevirCytochrome P450 3A4enzyme
DB11586AsunaprevirCytochrome P450 3A5enzyme
DB11586AsunaprevirCytochrome P450 2A6enzyme
DB11586AsunaprevirCytochrome P450 2B6enzyme
DB11586AsunaprevirCytochrome P450 2C9enzyme
DB11586AsunaprevirCytochrome P450 2C19enzyme
DB11586AsunaprevirCytochrome P450 2D6enzyme
DB11586AsunaprevirSolute carrier organic anion transporter family member 1B1transporter
DB11586AsunaprevirSolute carrier organic anion transporter family member 1B3transporter
DB11586AsunaprevirSolute carrier organic anion transporter family member 2B1transporter
DB11586AsunaprevirP-glycoprotein 1transporter
DB00194VidarabineDNAtarget
DB00194VidarabineDNA polymerase catalytic subunittarget
DB00194VidarabineThymidine kinasetarget
DB00194VidarabineThymidine kinasetarget
DB00194VidarabineAdenosine deaminaseenzyme
DB00249IdoxuridineThymidine kinasetarget
DB00249IdoxuridineDNAtarget
DB00787AcyclovirDNA polymerase catalytic subunittarget
DB00787AcyclovirDNA polymerase catalytic subunittarget
DB00787AcyclovirThymidine kinasetarget
DB00787AcyclovirSolute carrier family 22 member 1transporter
DB00787AcyclovirSolute carrier family 22 member 6transporter
DB00787AcyclovirSolute carrier family 22 member 8transporter
DB00787AcyclovirIleal sodium/bile acid cotransportertransporter
DB00787AcyclovirMultidrug and toxin extrusion protein 1transporter
DB00787AcyclovirMultidrug and toxin extrusion protein 2transporter
DB00787AcyclovirThymidine kinaseenzyme
DB00787AcyclovirGuanylate kinaseenzyme
DB00787AcyclovirNucleoside diphosphokinaseenzyme
DB00787AcyclovirPyruvate Kinasesenzyme
DB00787AcyclovirCreatine Kinasesenzyme
DB00787AcyclovirPhosphoglycerate Kinasesenzyme
DB00787AcyclovirSuccinyl-CoA Synthetasesenzyme
DB00787AcyclovirPhosphoenolpyruvate Carboxykinasesenzyme
DB00787AcyclovirAdenylosuccinate Synthetasesenzyme
DB00787AcyclovirSerum albumincarrier
DB01004GanciclovirDNA polymerase catalytic subunittarget
DB01004GanciclovirThymidine kinasetarget
DB01004GanciclovirSolute carrier family 22 member 1transporter
DB01004GanciclovirSolute carrier family 22 member 6transporter
DB01004GanciclovirSolute carrier family 22 member 8transporter
DB01004GanciclovirSolute carrier family 22 member 7transporter
DB01004GanciclovirDNAtarget
DB01004GanciclovirMultidrug and toxin extrusion protein 1transporter
DB01004GanciclovirMultidrug and toxin extrusion protein 2transporter
DB01264DarunavirHuman immunodeficiency virus type 1 proteasetarget
DB01264DarunavirCytochrome P450 3A4enzyme
DB01264DarunavirSolute carrier organic anion transporter family member 1B1transporter
DB01264DarunavirP-glycoprotein 1transporter
DB06290SimeprevirNS3 proteasetarget
DB06290SimeprevirSerum albumincarrier
DB06290SimeprevirCytochrome P450 1A2enzyme
DB06290SimeprevirP-glycoprotein 1transporter
DB06290SimeprevirSolute carrier organic anion transporter family member 1B1transporter
DB06290SimeprevirSolute carrier organic anion transporter family member 1B3transporter
DB06290SimeprevirCytochrome P450 3A4enzyme
DB06290SimeprevirCanalicular multispecific organic anion transporter 1transporter
DB06290SimeprevirATP-binding cassette sub-family G member 2transporter
DB06290SimeprevirSolute carrier organic anion transporter family member 2B1transporter
DB06290SimeprevirSodium/bile acid cotransportertransporter
DB06290SimeprevirBile salt export pumptransporter
DB13997Baloxavir marboxilATP-binding cassette sub-family B member 5transporter
DB13997Baloxavir marboxilUDP-glucuronosyltransferase 1-3enzyme
DB13997Baloxavir marboxilCytochrome P450 3A4enzyme
DB13997Baloxavir marboxilPolymerase acidic proteintarget
DB03312BrivudineThymidine kinasetarget
DB06614PeramivirNeuraminidasetarget
DB06614PeramivirNeuraminidasetarget
DB06614PeramivirNeuraminidasetarget
DB11574ElbasvirNonstructural protein 5Atarget
DB11574ElbasvirP-glycoprotein 1transporter
DB11574ElbasvirCytochrome P450 3A4enzyme
DB11574ElbasvirCytochrome P450 3A5enzyme
DB11574ElbasvirCytochrome P450 3A7enzyme
DB11574ElbasvirCytochrome P450 3A43enzyme
DB11575GrazoprevirP-glycoprotein 1transporter
DB11575GrazoprevirSolute carrier organic anion transporter family member 1B1transporter
DB11575GrazoprevirSolute carrier organic anion transporter family member 1B3transporter
DB11575GrazoprevirCytochrome P450 3A4enzyme
DB11575GrazoprevirNS3/4A proteintarget
DB11575GrazoprevirSerum albumincarrier
DB11575GrazoprevirAlpha-1-acid glycoprotein 1carrier
DB11613VelpatasvirCytochrome P450 2B6enzyme
DB11613VelpatasvirCytochrome P450 2C8enzyme
DB11613VelpatasvirCytochrome P450 3A4enzyme
DB11613VelpatasvirNonstructural protein 5Atarget
DB11613VelpatasvirP-glycoprotein 1transporter
DB11613VelpatasvirATP-binding cassette sub-family G member 2transporter
DB11613VelpatasvirSolute carrier organic anion transporter family member 1B1transporter
DB11613VelpatasvirSolute carrier organic anion transporter family member 1B3transporter
DB11613VelpatasvirSolute carrier organic anion transporter family member 2B1transporter
DB11799BictegravirReverse transcriptase/RNaseHtarget
DB11799BictegravirIntegrasetarget
DB11799BictegravirCytochrome P450 3A4enzyme
DB11799BictegravirUDP-glucuronosyltransferase 1-1enzyme
DB11799BictegravirPOU domain, class 2, transcription factor 2enzyme
DB11799BictegravirMultidrug and toxin extrusion protein 1enzyme
DB12026VoxilaprevirCytochrome P450 3A4enzyme
DB12026VoxilaprevirCytochrome P450 1A2enzyme
DB12026VoxilaprevirCytochrome P450 2C8enzyme
DB12026VoxilaprevirNS3/4A proteintarget
DB12026VoxilaprevirP-glycoprotein 1transporter
DB12026VoxilaprevirATP-binding cassette sub-family G member 2transporter
DB12026VoxilaprevirSolute carrier organic anion transporter family member 1B1transporter
DB12026VoxilaprevirSolute carrier organic anion transporter family member 1B3transporter
DB12070LetermovirUDP-glucuronosyltransferase 1-1enzyme
DB12070LetermovirUDP-glucuronosyltransferase 1-3enzyme
DB12070LetermovirSolute carrier organic anion transporter family member 1B1transporter
DB12070LetermovirSolute carrier organic anion transporter family member 1B3transporter
DB12070LetermovirTripartite terminase subunit 1target
DB12070LetermovirTripartite terminase subunit 2target
DB12070LetermovirTripartite terminase subunit 3target
DB12070LetermovirCytochrome P450 2D6enzyme
DB12070LetermovirCytochrome P450 2C8enzyme
DB12070LetermovirCytochrome P450 2C19enzyme
DB12070LetermovirCytochrome P450 2C9enzyme
DB12070LetermovirCytochrome P450 2B6enzyme
DB12070LetermovirP-glycoprotein 1transporter
DB12070LetermovirATP-binding cassette sub-family G member 2transporter
DB12070LetermovirBile salt export pumptransporter
DB12070LetermovirSolute carrier family 22 member 8transporter
DB12070LetermovirCanalicular multispecific organic anion transporter 1transporter
DB12070LetermovirCytochrome P450 3A4enzyme
DB12070LetermovirCytochrome P450 3A5enzyme
DB12070LetermovirCytochrome P450 3A7enzyme
DB12070LetermovirCytochrome P450 3A43enzyme
DB12301DoravirineCytochrome P450 3A4enzyme
DB12301DoravirineCytochrome P450 3A5enzyme
DB12301DoravirineReverse transcriptase/RNaseHtarget
DB12698IbalizumabT-cell surface glycoprotein CD4target
DB12698IbalizumabC-C chemokine receptor type 5target
DB12698IbalizumabC-X-C chemokine receptor type 4target
DB13878PibrentasvirNonstructural protein 5Atarget
DB13878PibrentasvirCytochrome P450 3A Subfamilyenzyme
DB13878PibrentasvirUDP-glucuronosyltransferase 1-1enzyme
DB13878PibrentasvirP-glycoprotein 1transporter
DB13878PibrentasvirATP-binding cassette sub-family G member 2transporter
DB13878PibrentasvirSolute carrier organic anion transporter family member 1B1transporter
DB13878PibrentasvirSolute carrier organic anion transporter family member 1B3transporter
DB13879GlecaprevirCytochrome P450 3A Subfamilyenzyme
DB13879GlecaprevirUDP-glucuronosyltransferase 1-1enzyme
DB13879GlecaprevirP-glycoprotein 1transporter
DB13879GlecaprevirATP-binding cassette sub-family G member 2transporter
DB13879GlecaprevirSolute carrier organic anion transporter family member 1B1transporter
DB13879GlecaprevirSolute carrier organic anion transporter family member 1B3transporter
DB13879GlecaprevirNS3 proteasetarget