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Displaying drugs 951 - 975 of 1070 in total

Lemborexant

Lemborexant is a novel dual orexin receptor antagonist used in the treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance. Recent research in the field of sleep disorders has revealed that insomnia is likely driven not by the inability of the brain to "switch on" sleep-related circuits,...
Approved
Investigational
Matched Description: … receptors, lemborexant and other orexin antagonists (e.g. ... receptor antagonist used in the treatment of insomnia characterized by difficulties with sleep onset and ... [zopiclone], [zolpidem], benzodiazepines) focus on enhancing sleep drive via modulation of GABA and melatonin …
Matched Categories: … Hypnotics and Sedatives ... Sleep Initiation and Maintenance Disorders …
Matched Products: … DAYVIGO FILM-COATED TABLET 5MG ... DAYVIGO FILM-COATED TABLET 10MG …

Albendazole

A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Approved
Vet approved
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Products: … DENZOL 200mg Film Coated Tablets ... ALZOL 200 MG FİLM KAPLI TABLET ... HELMADOL 200 MG FİLM KAPLI TABLET, 6 ADET …

Linezolid

Linezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. Its effects are bacteriostatic against both enterococci and staphylococci and bactericidal against most isolates of streptococci. Linezolid exerts its antibacterial activity by inhibiting the initiation of bacterial protein synthesis - more specifically,...
Approved
Investigational
Matched Description: … Its effects are bacteriostatic against both enterococci and staphylococci and bactericidal against most ... generally more effective and tolerable than its predecessor. ... synthesis - more specifically, it binds to the 23S ribosomal RNA of the 50S subunit[A11227,A199050] and …
Matched Products: … LYNOZID 600 MG FILM TABLET ,2 FILM TABLET ... LYNOZID 600 MG FILM TABLET ,FILM TABLET, 10 ADET ... LIMEXID 600 MG FILM TABLET, 2 ADET …

Gilteritinib

Gilteritinib, also known as ASP2215, is a small molecule part of the FLT3 tyrosine kinase inhibitors that presented a greater selectivity and potency when compared with other agents from this group. It is a pyrazinecarboxamide derivative that showed high selectivity to FLT3 preventing the c-Kit -driven myelosuppression observed in other...
Approved
Investigational
Matched Description: … is a small molecule part of the FLT3 tyrosine kinase inhibitors that presented a greater selectivity and ... [A40044] Gilteritinib was developed by Astellas Pharma and FDA approved on November 28, 2018. ... This drug was approved after being designed as an orphan drug with a fast track and priority review status …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … XOSPATA® FILM-COATED TABLETS 40MG ... XOSPATA 40 MG FİLM KAPLI TABLET, 84 ADET …

Granisetron

A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Approved
Investigational
Matched Description: … A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant …
Matched Categories: … Alimentary Tract and Metabolism ... Antiemetics and Antinauseants …
Matched Products: … SETRON 1 MG FILM TABLET, 10 ADET ... KYTRIL 2 MG FİLM KAPLI TABLET, 10 ADET ... GRANITRON 2 MG FILM TABLET ,5 TABLET …

Apalutamide

Apalutamide is a potent androgen receptor (AR) antagonist that selectively binds to the ligand-binding domain of AR and blocks AR nuclear translocation or binding to androgen response elements . It has been used in trials studying the treatment of Prostate Cancer, Hepatic Impairment, Prostatic Neoplasms, Castration-Resistant Prostate Cancer, and Prostatic...
Approved
Investigational
Matched Description: … It targets the AR ligand-binding domain and prevents AR nuclear translocation, DNA binding, and transcription ... potent androgen receptor (AR) antagonist that selectively binds to the ligand-binding domain of AR and ... risk for metastases and death [A31846]. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Products: … Erleada 60mg Film-Coated Tablets ... ERLEADA FILM-COATED TABLET 60MG …

Sirolimus

Sirolimus, also known as rapamycin, is a macrocyclic lactone antibiotic produced by bacteria Streptomyces hygroscopicus, which was isolated from the soil of the Vai Atari region of Rapa Nui (Easter Island). It was first isolated and identified as an antifungal agent with potent anticandida activity; however, after its potent antitumor...
Approved
Investigational
Matched Description: … extensively investigated as an immunosuppressive and antitumour agent. ... [A242412] It was first isolated and identified as an antifungal agent with potent anticandida activity ... ; however, after its potent antitumor and immunosuppressive activities were later discovered, it was …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Sirolimus and Prodrugs …
Matched Products: … RAPAMUNE 1 MG 100 FILM DRAJE ... RAPAMUNE 1 MG FILM DRAJE, 30 ADET …

Benfotiamine

Benfotiamine has been investigated for the treatment and prevention of Diabetic Nephropathy and Diabetes Mellitus, Type 2.
Approved
Experimental
Matched Description: … Benfotiamine has been investigated for the treatment and prevention of Diabetic Nephropathy and Diabetes …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … NEVRALON B 300 MG FİLM KAPLI TABLET, 30 TABLET ... NEVRALON B 150 MG FİLM KAPLI TABLET, 30 TABLET …

Trazodone

Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants. It is used in adults and has been shown to be comparable in efficacy to other drugs such as tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine receptor inhibitor (SNRIs) in the...
Approved
Investigational
Matched Description: … Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors ... [A181180] It is used in adults and has been shown to be comparable in efficacy to other drugs such as ... tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine …
Matched Categories: … Serotonin antagonist and reuptake inhibitors (SARIs) …
Matched Products: … DESYREL XL 150 MG UZATILMIŞ SALIMLI FİLM TABLET , 10 TABLET ... DESYREL XL 150 MG UZATILMIŞ SALIMLI FİLM TABLET , 14 TABLET ... DESYREL XL 150 MG UZATILMIŞ SALIMLI FİLM TABLET , 20 TABLET …

Pioglitazone

Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus.[L11416,L11419,L11422,L11425] It is administered as a racemic mixture, though there is no pharmacologic difference between the enantiomers and they appear to interconvert in vivo with little consequence. The thiazolidinedione class...
Approved
Investigational
Matched Description: … Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications ... affect numerous metabolic processes, most notably lipid and glucose homeostasis. ... administered as a racemic mixture, though there is no pharmacologic difference between the enantiomers and …
Matched Mixtures name: … Pioglitazone and metformin ... Pioglitazone and Metformin Hydrocholride ... Pioglitazone and Metformin Hydrocholride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and pioglitazone ... pioglitazone and alogliptin ... glimepiride and pioglitazone ... pioglitazone and sitagliptin …
Matched Products: … PIONDIA 15 MG FILM TABLET, 60 ADET ... PIONDIA 30 MG FILM TABLET, 60 ADET ... PIONDIA 45 MG FILM TABLET, 60 ADET …

Cephalexin

Cephalexin is the first of the first generation cephalosporins.[A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,Label] Cephalexin was approved by the FDA on 4 January 1971.
Approved
Investigational
Vet approved
Matched Description: … [A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. …
Matched Products: … IELEXIN 500 MG FILM TABLET ... MAKSIPOR 1 GR FILM TABLET, 10 ADET ... MAKSIPOR 1 GR FILM TABLET, 20 ADET …

Sorafenib

Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also...
Approved
Investigational
Matched Description: … Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. ... in tumour cell proliferation and tumour angiogenesis. ... It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … NEXAVAR FILM-COATED TABLETS 200 MG ... NEXAVAR 200 MG FILM KAPLI TABLET, 112 ADET …

Rufinamide

Rufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy. Clinical trials suggest its efficacy in the treatment of partial seizures.
Approved
Matched Description: … Rufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like …
Matched Products: … Inovelon 200 mg film-coated tablets ... INOVELON FILM-COATED TABLET 200 MG …

Regorafenib

Regorafenib is an orally-administered inhibitor of multiple kinases. It is used for the treatment of metastatic colorectal cancer, advanced gastrointestinal stromal tumours, and hepatocellular carcinoma. FDA approved on September 27, 2012. Approved use of Regorafenib was expanded to treat Hepatocellular Carcinoma in April 2017.
Approved
Matched Description: … used for the treatment of metastatic colorectal cancer, advanced gastrointestinal stromal tumours, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … STIVARGA 40MG FILM-COATED TABLETS ... STIVARGA 40 MG FILM KAPLI TABLET ,84 ADET …

Naltrexone

Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
Approved
Investigational
Vet approved
Matched Description: … It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and …
Matched Mixtures name: … Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release …
Matched Categories: … Alimentary Tract and Metabolism ... oxycodone and naltrexone ... bupropion and naltrexone …
Matched Products: … ETHYLEX 50 MG FILM TABLET, 28 ADET ... NOKREV 50 MG FİLM KAPLI TABLET, 28 ADET …

Gentamicin

Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from Micromonospora purpurea in 1963. It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability.[A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but is particularly useful for the treatment...
Approved
Vet approved
Matched Description: … Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea_ ... is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and ... [A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but …
Matched Mixtures name: … Garasone Ophthalmic and Otic Solution ... Diprogenta - Salbe …
Matched Categories: … Ophthalmological and Otological Preparations …
Matched Products: … INFECTOGENTA SALBE 0.1% …

Cyclobenzaprine

Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from Amitriptyline by only a single double bond.[A185039,A184982] Since its approval, it has...
Approved
Matched Description: … Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been …
Matched Products: … FLESSİ 5 MG FİLM KAPLI TABLET, 30 ADET ... FLESSİ 10 MG FİLM KAPLI TABLET, 30 ADET ... SPAZBEN 5 MG FİLM KAPLI TABLET, 30 ADET …

Amitriptyline

Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.
Approved
Matched Mixtures name: … Perphenazine and Amitriptyline Hydrochloride ... Perphenazine and Amitriptyline Hydrochloride ... Chlordiazepoxide and Amitriptyline Hydrochloride …
Matched Categories: … amitriptyline and psycholeptics ... Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … TRIPTILIN 10 MG FİLM TABLET (30 TABLET) ... TRIPTILIN 25 MG FİLM TABLET (40 TABLET) ... LAROXYL 10 MG FİLM KAPLI TABLET, 30 ADET …

Ketorolac

Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution. It's analgesic properties make it a useful pain management tool across many settings including postoperative pain, rheumatoid arthritis, osteoarthritis, menstrual disorders, headaches, spinal and soft tissue pain,...
Approved
Matched Description: … tablet, injectable, nasal spray and as an ophthalmic solution. ... soft tissue pain, and ankylosing spondylitis. ... Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Mydriatics and Cycloplegics ... Antiinflammatory and Antirheumatic Products ... phenylephrine and ketorolac ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … KETO FILM COATED TABLET 10MG ... KETO FILM COATED TABLET 10 mg ... YSP KETO FILM COATED TABLET 10MG …

Ibandronate

Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to zoledronic acid, minodronic acid, and risedronic acid.[A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs. Ibandronate was granted FDA...
Approved
Investigational
Matched Description: … [A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis. ... third generation, nitrogen containing bisphosphonate similar to [zoledronic acid], [minodronic acid], and …
Matched Mixtures name: … IBAMIN D3 150 MG/2800 IU FİLM KAPLI TABLET, 3 ADET …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... ibandronic acid and colecalciferol …
Matched Products: … Bonviva Film-Coated Tablets 150mg ... BONVIVA FILM-COATED TABLETS 150 MG ... IBAMAX 150 MG FILM TABLET, 3 ADET …

Secnidazole

Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. It is structurally related to other 5-nitroimidazoles, including DB00916 and DB00911, but displays improved oral absorption and a longer terminal elimination half-life than other drugs in this class. Secnidazole is selective against many anaerobic Gram-positive and Gram-negative bacteria as well as protozoa. Once...
Approved
Matched Description: … It is structurally related to other 5-nitroimidazoles, including [DB00916] and [DB00911], but displays ... to form a radical anion, thereby damaging and killing the target pathogen. ... improved oral absorption and a longer terminal elimination half-life than other drugs in this class. …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... azithromycin, fluconazole and secnidazole …
Matched Products: … SECNIDOX 500 MG FILM TABLET ,2 FILM TABLET ... SECNIDOX 500 MG FILM TABLET ,4 FILM TABLET ... SECNIDOX 1000 MG FILM TABLET,2 ADET …

Ulipristal

Ulipristal is a selective progesterone receptor modulator used for the purposes of emergency contraception (Ella) and for the treatment of uterine fibroids (Fibristal). It is a derivative of 19-norprogesterone and has both antagonistic and partial agonist activity at the progesterone receptor. It also binds to glucocorticoid receptor, however compared to...
Approved
Matched Description: … It is a derivative of 19-norprogesterone and has both antagonistic and partial agonist activity at the ... a selective progesterone receptor modulator used for the purposes of emergency contraception (Ella) and ... has lower glucocorticoid activity and better binding affinity. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System …
Matched Products: … ELLA 30 MG FİLM KAPLI TABLET, 1 TABLET ... ULPİSAD 30 MG FİLM KAPLI TABLET, 1 ADET …

Zuclopenthixol

Zuclopenthixol, also known as Zuclopentixol or Zuclopenthixolum, is an antipsychotic agent. Zuclopenthixol is a thioxanthene-based neuroleptic with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors. Major brands of zuclopenthixol are Cisordinol, Acuphase, and Clopixol. This drug is a liquid. This compound...
Approved
Investigational
Matched Description: … Major brands of zuclopenthixol are Cisordinol, Acuphase, and Clopixol. This drug is a liquid. ... It is an antagonist at D1 and D2 dopamine receptors. ... hydroxytryptamine receptor 2A, D(1B) dopamine receptor, D(2) dopamine receptor, D(1A) dopamine receptor, and …
Matched Products: … CLOPIXOL 2 MG FILM TABLET, 50 ADET ... CLOPİXOL 25 MG FİLM KAPLI TABLET, 20 ADET ... CLOPİXOL 10 MG FİLM KAPLI TABLET, 100 ADET …

Ritonavir

Ritonavir is an HIV protease inhibitor that interferes with the reproductive cycle of HIV. Although it was initially developed as an independent antiviral agent, it has been shown to possess advantageous properties in combination regimens with low-dose ritonavir and other protease inhibitors. It is now more commonly used as a...
Approved
Investigational
Matched Description: … formulations and as capsules. ... - and Health Canada-approved product Technivie. ... protease inhibitors such as [DB09297] and overall drug exposure. …
Matched Mixtures name: … Lopinavir and Ritonavir ... Lopinavir and ritonavir ... Lopinavir and ritonavir …
Matched Categories: … lopinavir and ritonavir ... darunavir and ritonavir ... atazanavir and ritonavir ... nirmatrelvir and ritonavir ... ombitasvir, paritaprevir and ritonavir …
Matched Products: … Ritonavir film coated ... NORVIR 100 MG FILM TABLET, 30 ADET …

Chloroquine

Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine and its derivative hydroxychloroquine have since been repurposed for the treatment of a...
Approved
Investigational
Vet approved
Matched Description: … treat malaria until the development of newer antimalarials such as [pyrimethamine], [artemisinin], and ... [A191787] Chloroquine and its derivative [hydroxychloroquine] have since been repurposed for the treatment ... of a number of other conditions including HIV, systemic lupus erythematosus, and rheumatoid arthritis …
Matched Categories: … chloroquine and proguanil ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … KUTLU 250 MG FİLM KAPLI TABLET, 30 ADET ... KUTLU 250 MG FİLM KAPLI TABLET, 10 ADET ... KUTLU 250 MG FİLM KAPLI TABLET, 1000 ADET …
Displaying drugs 951 - 975 of 1070 in total