Antifungal Agents

Name
Antifungal Agents
Accession Number
DBCAT000200
Description

Antibiotics inhibiting the growth of or killing fungi and used in the treatment of various fungal diseases.

Drugs
DrugDrug Description
FluconazoleA triazole antifungal used to treat various fungal infections including candidiasis.
OxiconazoleA topical antifungal used to treat a variety of dermatophyte infections.
TerconazoleAn antifungal drug used in the treatment of vulvovaginal candidiasis.
ClotrimazoleA topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
AnidulafunginAn antifungal used in the treatment of several types of candida infections.
GriseofulvinAn antifungal agent used to treat a variety of superficial tinea infections and fungal infections of the fingernails and toes.
CaspofunginAn echinocandin used to treat a variety of fungal infections.
TolnaftateAn antifungal agent used to treat various skin infections caused by fungi.
VoriconazoleA triazole compound used to treat fungal infections.
ButoconazoleAn imidazole antifungal used to treat vulvovaginal candidiasis.
NystatinA polyene ionophore antifungal used to treat cutaneous, mucocutaneous, and gastrointestinal mycotic infections, particularly those caused by Candida species.
Amphotericin BAn antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis.
NaftifineAn antifungal agent used to treat infections of the Tinea, Trichophyton, and Epidermophyton species.
PentamidineAn antifungal agent used to treat Pneumocystis pneumonia in patients infected with HIV.
HaloproginUsed to treat fungal (Tinea) skin infections such as athlete's foot, jock itch, ringworm, and tinea versicolor.
NatamycinA macrolide antifungal used to treat fungal infections of the eye.
TerbinafineAn allylamine antifungal used to treat dermatophyte infections of toenails and fingernails as well as other fungal skin infections.
SirolimusAn mTOR inhibitor immunosuppressant used to prevent organ transplant rejections, treat lymphangioleiomyomatosis, and treat adults with perivascular epithelioid cell tumors.
Salicylic acidAn acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.
TioconazoleAn imidazole antifungal used to treat vulvovaginal candidiasis.
KetoconazoleA broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.
CeruleninFor use as a biochemical tool, Cerulenin is shown to cause dramatic weight loss in animals
ButenafineA topical antifungal used to treat tinea versicolor, tinea pedis, tinea cruris, and tinea corporis.
FlucytosineAn antifungal indicated only to treat severe infections throughout the body caused by susceptible strains of Candida or Cryptococcus.
MiconazoleAn azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis.
EconazoleA topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor.
MicafunginAn antifungal agent used for the treatment of candidemia, acute disseminated candidiasis, and certain other invasive Candida infections, and for the prophylaxis of Candida infections during stem cell transplantation.
CandicidinUsed in the topical treatment of vulvovaginal candidiasis.
SertaconazoleA topical antifungal agent used in the treatment of interdigital tinea pedis in immunocompetent patients.
ItraconazoleA triazole antifungal agent used to treat various fungal infections, such as blastomycosis and onychomycosis.
CiclopiroxA broad-spectrum topical antifungal agent used to treat mild to moderate onychomycosis of fingernails and toenails in immunocompetent patients.
ChloroxineAn antibacterial agent used for the treatment of dandruff and mild to moderately severe seborrheic dermatitis of the scalp.
PosaconazoleA triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
NitroxolineNitroxoline is an antibiotic agent.
SinefunginSinefungin is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar. The proteins that adenosyl-ornithine target include...
ThymolAn essential oil found in various over-the-counter antibacterial and antifungal products.
RadicicolNot Available
Benzoic acidAn antimicrobial food additive.
Salicylhydroxamic AcidNot Available
MyxothiazolNot Available
LawsoneNot Available
BifonazoleAn azole antifungal drug used to treat fungal skin infections, such as dermatomycosis.
MevastatinNot used therapeutically due to its many side effects.
Bafilomycin A1The bafilomycins refer to a category of toxic macrolide antibiotics that are derivatives of Streptomyces griseus. These compounds all appear in the same fermentation and have similar biological activity. Bafilomycins...
SulconazoleA topical antifungal agent used for the treatment of tinea cruris, tinea corporis, and tinea versicolor caused by susceptible fungal strains.
IsoconazoleAn imidazole antifungal used for superficial skin and vaginal infections.
HexetidineAn topical antiseptic agent used for disinfection and prevention of bacterial, fungal and yeast infections of the oral and vaginal mucosa.
MiltefosineAn antileishmanial agent used to treat leishmaniasis, a group of disease caused by parasites of the Leishmania type.
EfinaconazoleAn antifungal agent used to treat onychomycosis, a fungal infection of the nail.
TavaboroleAn antifungal agent used to treat onychomycosis, a fungal infection of the nail.
AmorolfineA morpholine derivative commonly applied as a lacquer for onychomycosis but is also used for superficial dermatomycosis.
CordycepinCordycepin has been used in trials studying the treatment of Leukemia.
Nikkomycin ZNikkomycin Z has been used in trials studying the treatment and basic science of Coccidioidomycosis.
TolciclateNot Annotated
FlutrimazoleA topical antifungal used to treat pityriasis capitis and seborrheic dermatitis.
FenticonazoleAn imidazole antifungal used to treat a variety of topical fungal infections.
PyrrolnitrinNot Annotated
MepartricinA medication indicated in the treatment of benign prostatic hyperplasia, vaginal candidiasis, or trichomoniasis.
OmoconazoleNot Annotated
NifuratelA nitrofuran derivative indicated in the treatment of leucorrhea, vulvovaginal infections, and urinary tract infections.
WortmanninWortmannin is a steroid metabolite of Penicillium funiculosum and Talaromyces wortmannii fungi. This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks).
Capric acidDecanoic acid is a solid. This compound belongs to the straight chain fatty acids. These are fatty acids with a straight aliphatic chain. The proteins that decanoic acid targets include...
AlbaconazoleAlbaconazole has been used in trials studying the basic science of Onychomycosis.
IsavuconazoleIndicated for patients 18 years of age and older for the treatment of invasive aspergillosis [FDA Label]. Indicated for patients 18 years of age and older for the treatment of...
RavuconazoleInvestigated for use/treatment in fungal infections, aspergillosis, candidiasis, and onychomycosis.
AbafunginInvestigated for use/treatment in fungal infections, bacterial infection, skin infections/disorders, and onychomycosis.
IsavuconazoniumA triazole antifungal used for the treatment of invasive aspergillosis and mucormycosis.
LuliconazoleA topical antifungal agent used to treat fungal infections.
PecilocinNot Annotated
PentamycinNot Annotated
BasifunginBasifungin, also known as aureuobacidin A, is a phosphorylceramide synthase inhibitor , .
PyrithioneAn antimicrobial agent used for the treatment of dandruff and seborrheic dermatitis.
PyroquilonPyroquilon is a commercial blasticide which binds in the naphthol pocket of fungal trihydroxynaphthalene reductase active site.
OlorofimOlorofim is under investigation in clinical trial NCT03340597 (Assessment of Varying Oral Dosing Regimens for F901318 in Healthy Subjects).
Potassium iodateNot Annotated
TrocloseneNot Annotated
TriacetinAn acetylating agent indicated in the treatment of ringworm.
EfungumabEfungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel in Advanced Breast Cancer).
RezafunginAn echinocandin antifungal indicated in patients over 18 years old who have limited or no alternative options for the treatment of candidemia and invasive candidiasis.
LevoketoconazoleOne of two enantiomeric forms of racemic ketoconazole that strongly inhibits multiple steroidogenic enzymes and is used for the symptomatic treatment of endogenous Cushing's syndrome.
IbrexafungerpA triterpene antifungal indicated in the treatment of vulvovaginal candidiasis and prevention of recurrent vulvovaginal candidiasis in post-menarchal patients.
Trichostatin ANot Available
OteseconazoleAn azole antifungal used to prevent recurrent vulvovaginal candidiasis in females who are not of reproductive potential.
AjoeneNot Annotated
VL-2397Not Annotated
Drugs & Drug Targets
DrugTargetType
FluconazoleCytochrome P450 3A4enzyme
FluconazoleCytochrome P450 2C9enzyme
FluconazoleCytochrome P450 2C19enzyme
FluconazoleP-glycoprotein 1transporter
FluconazoleCytochrome P450 51target
FluconazoleCytochrome P450 3A5enzyme
OxiconazoleCytochrome P450 51target
OxiconazoleLanosterol synthasetarget
OxiconazoleCytochrome P450 3A4enzyme
OxiconazoleCytochrome P450 2C19enzyme
OxiconazoleNuclear receptor subfamily 1 group I member 2target
TerconazoleCytochrome P450 51target
ClotrimazoleIntermediate conductance calcium-activated potassium channel protein 4target
ClotrimazoleCytochrome P450 2D6enzyme
ClotrimazoleCytochrome P450 2C8enzyme
ClotrimazoleCytochrome P450 3A4enzyme
ClotrimazoleCytochrome P450 2B6enzyme
ClotrimazoleP-glycoprotein 1transporter
ClotrimazoleCytochrome P450 2A6enzyme
ClotrimazoleCytochrome P450 2C9enzyme
ClotrimazoleCytochrome P450 2E1enzyme
ClotrimazoleCytochrome P450 3A7enzyme
ClotrimazoleCytochrome P450 51target
ClotrimazoleNuclear receptor subfamily 1 group I member 2target
ClotrimazoleHydroxycarboxylic acid receptor 2target
ClotrimazoleBile salt export pumptransporter
ClotrimazoleSolute carrier organic anion transporter family member 1B1transporter
ClotrimazoleSolute carrier organic anion transporter family member 1B3transporter
ClotrimazoleErgosteroltarget
Anidulafungin1,3-beta-glucan synthase component FKS1target
GriseofulvinKeratin, type I cytoskeletal 12target
GriseofulvinCytochrome P450 1A2enzyme
GriseofulvinCytochrome P450 3A4enzyme
GriseofulvinTubulin beta chaintarget
CaspofunginSolute carrier family 22 member 1transporter
CaspofunginP-glycoprotein 1transporter
CaspofunginSolute carrier family 22 member 6transporter
CaspofunginSolute carrier organic anion transporter family member 1B1transporter
CaspofunginSolute carrier organic anion transporter family member 1B3transporter
CaspofunginCytochrome P450 3A4enzyme
Caspofungin1,3-beta-glucan synthase component FKS1target
TolnaftateSqualene monooxygenasetarget
VoriconazoleCytochrome P450 2C19enzyme
VoriconazoleCytochrome P450 3A4enzyme
VoriconazoleCytochrome P450 2C9enzyme
VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
VoriconazoleCytochrome P450 3A5enzyme
VoriconazoleCytochrome P450 3A7enzyme
VoriconazoleProstaglandin G/H synthase 1enzyme
VoriconazoleCytochrome P450 51target
VoriconazoleCytochrome P450 2B6enzyme
ButoconazoleErgosteroltarget
NystatinErgosteroltarget
NystatinSolute carrier organic anion transporter family member 1B1transporter
NystatinSolute carrier organic anion transporter family member 1B3transporter
Amphotericin BErgosteroltarget
NaftifineSqualene monooxygenasetarget
PentamidineDNAtarget
PentamidineCytochrome P450 2C19enzyme
PentamidinetRNA (cytosine(38)-C(5))-methyltransferasetarget
PentamidineCytochrome P450 2D6enzyme
PentamidineCytochrome P450 1A1enzyme
PentamidineCytochrome P450 3A5enzyme
PentamidineCytochrome P450 4A11enzyme
NatamycinErgosteroltarget
TerbinafineSqualene monooxygenasetarget
TerbinafineCytochrome P450 2D6enzyme
TerbinafineCytochrome P450 2C9enzyme
TerbinafineCytochrome P450 1A2enzyme
TerbinafineCytochrome P450 3A4enzyme
TerbinafineCytochrome P450 2C8enzyme
TerbinafineCytochrome P450 2C19enzyme
TerbinafineProstaglandin G/H synthase 1enzyme
TerbinafineSerum albumincarrier
Terbinafinealpha1-acid glycoproteincarrier
TerbinafineABC multidrug transporter MDR2transporter
TerbinafineSqualene monooxygenasetarget
SirolimusCytochrome P450 3A4enzyme
SirolimusSerine/threonine-protein kinase mTORtarget
SirolimusCytochrome P450 3A5enzyme
SirolimusCytochrome P450 3A7enzyme
SirolimusP-glycoprotein 1transporter
SirolimusSolute carrier organic anion transporter family member 1B1transporter
SirolimusMultidrug and toxin extrusion protein 1transporter
SirolimusSerum albumincarrier
SirolimusAlpha-1-acid glycoprotein 1carrier
SirolimusApolipoproteinscarrier
Salicylic acidSerum albumincarrier
Salicylic acidProstaglandin G/H synthase 1target
Salicylic acidProstaglandin G/H synthase 2target
Salicylic acidAldo-keto reductase family 1 member C1target
Salicylic acidSolute carrier family 22 member 6transporter
Salicylic acidSolute carrier family 22 member 10transporter
Salicylic acidSolute carrier family 22 member 8transporter
Salicylic acidSolute carrier family 22 member 11transporter
Salicylic acidSolute carrier organic anion transporter family member 2B1transporter
Salicylic acidMonocarboxylate transporter 1transporter
Salicylic acidSolute carrier family 22 member 7transporter
Salicylic acidCytochrome P450 2C9enzyme
TioconazoleLanosterol 14-alpha demethylasetarget
TioconazoleCytochrome P450 19A1enzyme
TioconazoleCytochrome P450 2C19enzyme
TioconazoleCytochrome P450 2E1enzyme
TioconazoleCytochrome P450 3A4enzyme
TioconazoleCytochrome P450 51target
KetoconazoleCytochrome P450 3A4enzyme
KetoconazoleCytochrome P450 2C9enzyme
KetoconazoleCytochrome P450 2C19enzyme
KetoconazoleCytochrome P450 3A5enzyme
KetoconazoleCytochrome P450 1A2enzyme
KetoconazoleCytochrome P450 2C8enzyme
KetoconazoleCytochrome P450 1A1enzyme
KetoconazoleCytochrome P450 2D6enzyme
KetoconazoleBile salt export pumptransporter
KetoconazoleP-glycoprotein 1transporter
KetoconazoleCytochrome P450 11B1, mitochondrialenzyme
KetoconazoleCytochrome P450 1B1enzyme
KetoconazoleCytochrome P450 2A6enzyme
KetoconazoleCytochrome P450 2B6enzyme
KetoconazoleLanosterol 14-alpha demethylasetarget
KetoconazoleAndrogen receptortarget
KetoconazoleSteroid 17-alpha-hydroxylase/17,20 lyasetarget
KetoconazoleSteroid 21-hydroxylasetarget
KetoconazolePotassium voltage-gated channel subfamily H member 2target
KetoconazoleNuclear receptor subfamily 1 group I member 2target
KetoconazoleNuclear receptor subfamily 1 group I member 3target
KetoconazoleUDP-glucuronosyltransferase 1-1enzyme
KetoconazoleUDP-glucuronosyltransferase 2B7enzyme
KetoconazoleSolute carrier organic anion transporter family member 1B1transporter
KetoconazoleCytochrome P450 4F12enzyme
KetoconazoleLeukotriene-B(4) omega-hydroxylase 1enzyme
KetoconazoleSerum albumincarrier
KetoconazoleSex hormone-binding globulincarrier
KetoconazoleCytochrome P450 19A1enzyme
KetoconazoleUDP-glucuronosyltransferase 1-7enzyme
Cerulenin3-oxoacyl-[acyl-carrier-protein] synthase 3target
Cerulenin3-oxoacyl-[acyl-carrier-protein] synthase 2target
Cerulenin3-oxoacyl-[acyl-carrier-protein] synthase 1target
CeruleninFatty acid synthasetarget
ButenafineSqualene monooxygenasetarget
FlucytosineThymidylate synthasetarget
FlucytosineDNA (cytosine-5)-methyltransferase 1target
FlucytosineDNAtarget
MiconazoleCytochrome P450 2C9enzyme
MiconazoleCytochrome P450 2D6enzyme
MiconazoleCytochrome P450 3A4enzyme
MiconazoleP-glycoprotein 1transporter
MiconazoleCytochrome P450 51target
MiconazoleNitric oxide synthase, endothelialtarget
MiconazoleNitric oxide synthase, inducibletarget
MiconazoleCytochrome P450 11B1, mitochondrialenzyme
MiconazoleCytochrome P450 2A6enzyme
MiconazoleCytochrome P450 2B6enzyme
MiconazoleCytochrome P450 2C19enzyme
MiconazoleCytochrome P450 2E1enzyme
MiconazoleNuclear receptor subfamily 1 group I member 2target
MiconazoleLanosterol 14-alpha demethylaseenzyme
MiconazoleCytochrome P450 19A1enzyme
MiconazoleCalcium-activated potassium channeltarget
MiconazoleVoltage-gated Potassium Channelstarget
MiconazoleInward rectifier potassium channeltarget
MiconazoleVoltage gated L-type calcium channeltarget
MiconazoleSerum albumincarrier
MiconazoleCytochrome P450 2C8enzyme
EconazoleCytochrome P450 19A1enzyme
EconazoleCytochrome P450 2E1enzyme
EconazoleCytochrome P450 3A4enzyme
EconazoleCytochrome P450 51target
EconazoleNuclear receptor subfamily 1 group I member 2target
MicafunginArylsulfatase Aenzyme
MicafunginCatechol O-methyltransferaseenzyme
Micafungin1,3-beta-glucan synthase component FKS1target
CandicidinErgosteroltarget
CandicidinCytochrome P450 3A4enzyme
SertaconazoleCytochrome P450 51target
ItraconazoleCytochrome P450 3A4enzyme
ItraconazoleCytochrome P450 3A5enzyme
ItraconazoleCytochrome P450 3A7enzyme
ItraconazoleCytochrome P450 2B6enzyme
ItraconazoleP-glycoprotein 1transporter
ItraconazoleCytochrome P450 1A1enzyme
ItraconazoleCytochrome P450 2E1enzyme
ItraconazoleSolute carrier organic anion transporter family member 2B1transporter
ItraconazoleCytochrome P450 3A Subfamilyenzyme
ItraconazoleATP-binding cassette sub-family G member 2transporter
ItraconazoleSerum albumincarrier
ItraconazoleLanosterol 14-alpha demethylasetarget
CiclopiroxSodium/potassium-transporting ATPase subunit alpha-1target
PosaconazoleCytochrome P450 3A4enzyme
PosaconazoleP-glycoprotein 1transporter
PosaconazoleCytochrome P450 51target
NitroxolineMethionine aminopeptidase 2target
NitroxolineMagnesium cationtarget
NitroxolineManganese cationtarget
SinefunginModification methylase RsrItarget
SinefunginRdmBtarget
SinefunginrRNA adenine N-6-methyltransferasetarget
SinefunginModification methylase TaqItarget
RadicicolHeat shock protein HSP 90-betatarget
RadicicolEndoplasmintarget
RadicicolDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrialtarget
Radicicol[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrialtarget
RadicicolVirulence sensor histidine kinase PhoQtarget
Benzoic acidCocaine esterasetarget
Benzoic acidD-amino-acid oxidasetarget
Benzoic acidChlorocatechol 1,2-dioxygenasetarget
Benzoic acid2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolasetarget
Benzoic acidNon-heme chloroperoxidasetarget
Benzoic acidOxygen-insensitive NAD(P)H nitroreductasetarget
Benzoic acidHydroxyquinol 1,2-dioxygenasetarget
Benzoic acidReplication proteintarget
Benzoic acidSolute carrier organic anion transporter family member 2B1transporter
Benzoic acidSolute carrier family 22 member 8transporter
Benzoic acidMonocarboxylate transporter 1transporter
Benzoic acidSolute carrier family 15 member 1target
MyxothiazolCytochrome b-c1 complex subunit 1, mitochondrialtarget
BifonazoleCytochrome P450 2B6target
BifonazoleCytochrome P450 51target
BifonazoleCytochrome P450 19A1enzyme
BifonazoleCytochrome P450 2E1enzyme
BifonazoleCytochrome P450 3A4enzyme
Mevastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
MevastatinLiver carboxylesterase 1enzyme
Bafilomycin A1V-type proton ATPase catalytic subunit Atarget
SulconazoleCytochrome P450 1A2enzyme
SulconazoleCytochrome P450 2C9enzyme
SulconazoleCytochrome P450 2D6enzyme
SulconazoleLanosterol 14-alpha demethylasetarget
MiltefosinePhospholipase D1enzyme
MiltefosineP-glycoprotein 1target
EfinaconazoleLanosterol 14-alpha demethylasetarget
Tavaboroleleucine--tRNA ligasetarget
WortmanninPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
WortmanninSerine/threonine-protein kinase PLK1target
WortmanninPhosphatidylinositol 3-kinase regulatory subunit alphatarget
WortmanninPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
Capric acidSerum albumincarrier
Capric acid3-oxoacyl-[acyl-carrier-protein] synthase 1target
Capric acidFurintarget
Capric acidPeptostreptococcal albumin-binding proteintarget
Capric acidGlycolipid transfer proteintarget
Capric acidOctanoyltransferasetarget
Capric acidPutative uncharacterized protein tcp14target
Capric acidPeroxisome proliferator-activated receptor gammatarget
IsavuconazoleCytochrome P450 3A4enzyme
IsavuconazoleCytochrome P450 3A5enzyme
IsavuconazoleCytochrome P450 2C8enzyme
IsavuconazoleCytochrome P450 2C9enzyme
IsavuconazoleCytochrome P450 2C19enzyme
IsavuconazoleCytochrome P450 2D6enzyme
IsavuconazoleCytochrome P450 2B6enzyme
IsavuconazoleUDP-glucuronosyltransferase 1-9enzyme
IsavuconazoleUDP-glucuronosyltransferase 1-8enzyme
IsavuconazoleP-glycoprotein 1transporter
IsavuconazoleATP-binding cassette sub-family G member 2transporter
IsavuconazoleSolute carrier family 22 member 2transporter
IsavuconazoleLanosterol 14-alpha demethylasetarget
IsavuconazolePotassium voltage-gated channel subfamily H member 2target
IsavuconazoleVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
IsavuconazoleG protein-activated inward rectifier potassium channel 2target
IsavuconazoleG protein-activated inward rectifier potassium channel 3target
IsavuconazoleATP-sensitive inward rectifier potassium channel 11target
IsavuconazolePotassium voltage-gated channel subfamily A member 5target
IsavuconazolePotassium voltage-gated channel subfamily D member 3target
IsavuconazolePotassium voltage-gated channel subfamily KQT member 1target
IsavuconazoleSodium channel protein type 5 subunit alphatarget
IsavuconazoniumCytochrome P450 3A4enzyme
IsavuconazoniumP-glycoprotein 1transporter
IsavuconazoniumCytochrome P450 3A5enzyme
IsavuconazoniumCholinesteraseenzyme
IsavuconazoniumCytochrome P450 2C8enzyme
IsavuconazoniumCytochrome P450 2C9enzyme
IsavuconazoniumCytochrome P450 2C19enzyme
IsavuconazoniumCytochrome P450 2D6enzyme
IsavuconazoniumCytochrome P450 2B6enzyme
IsavuconazoniumATP-binding cassette sub-family G member 2transporter
IsavuconazoniumSolute carrier family 22 member 2transporter
IsavuconazoniumLanosterol 14-alpha demethylasetarget
IsavuconazoniumSerum albumincarrier
LuliconazoleCytochrome P450 51target
LuliconazoleCytochrome P450 3A4enzyme
LuliconazoleCytochrome P450 2C19enzyme
BasifunginInositol phosphorylceramide synthasetarget
Rezafungin1,3-beta-glucan synthase component FKS1target
Rezafungin1,3-beta-glucan synthase component GSC2target
LevoketoconazoleCytochrome P450 11B1, mitochondrialtarget
LevoketoconazoleLanosterol 14-alpha demethylasetarget
LevoketoconazoleCytochrome P450 3A4enzyme
LevoketoconazoleCytochrome P450 3A5enzyme
LevoketoconazoleSteroid 21-hydroxylaseenzyme
LevoketoconazoleP-glycoprotein 1transporter
LevoketoconazoleSteroid 17-alpha-hydroxylase/17,20 lyasetarget
LevoketoconazoleCytochrome P450 11B2, mitochondrialtarget
LevoketoconazoleCholesterol side-chain cleavage enzyme, mitochondrialtarget
LevoketoconazoleSolute carrier family 22 member 2transporter
LevoketoconazoleMultidrug and toxin extrusion protein 1transporter
LevoketoconazoleCytochrome P450 2B6enzyme
LevoketoconazoleCytochrome P450 2C8enzyme
LevoketoconazoleCytochrome P450 1A2enzyme
LevoketoconazoleCytochrome P450 7A1enzyme
LevoketoconazoleCytochrome P450 19A1enzyme
IbrexafungerpCytochrome P450 3A4enzyme
IbrexafungerpUDP-glucuronosyltransferases (UGTs)enzyme
IbrexafungerpSulfotransferaseenzyme
IbrexafungerpCytochrome P450 2C8enzyme
IbrexafungerpP-glycoprotein 1transporter
IbrexafungerpSolute carrier organic anion transporter family member 1B3transporter
IbrexafungerpSerum albumincarrier
Ibrexafungerp1,3-beta-glucan synthase component GSC2target
IbrexafungerpGTP-binding protein RHO1target
Trichostatin AHistone deacetylase 8target
Trichostatin AAcetoin utilization proteintarget
Trichostatin AHistone deacetylase 7target
Trichostatin ACaspase-8target
Trichostatin AProstaglandin E2 Receptorstarget
Trichostatin ATumor necrosis factortarget
OteseconazoleCytochrome P450 51target
OteseconazoleATP-binding cassette sub-family G member 2transporter