Antifungal Agents

Antibiotics inhibiting the growth of or killing fungi and used in the treatment of various fungal diseases.
DrugDrug NameDrug Indication
DB00196FluconazoleFor the treatment of fungal infections.
DB00239OxiconazoleFor treatment of dermal fungal infection.
DB00251TerconazoleFor the treatment of candidiasis (a yeast-like fungal infection) of the vulva and vagina.
DB00257ClotrimazoleFor the local treatment of oropharyngeal candidiasis and vaginal yeast infections, also used in fungal infections of the skin such as ringworm, athlete's foot, and jock itch.
DB00362AnidulafunginFor use in the treatment of the following fungal infections: Candidemia and other forms of Candida infections (intra-abdominal abscess, and peritonitis), Aspergillus infections, and esophageal candidiasis. Also considered an alternative treatment for oropharyngeal canaidiasis.
DB00400GriseofulvinFor the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.
DB00520CaspofunginFor the treatment of esophageal candidiasis and invasive aspergillosis in patients who are refractory to or intolerant of other therapies.
DB00525TolnaftateTolnaftate topical is used to treat skin infections such as athlete's foot, jock itch, and ringworm infections. Tolnaftate is also used, along with other antifungals, to treat infections of the nails, scalp, palms, and soles of the feet. The powder and powder aerosol may be used to prevent athlete's foot.
DB00582VoriconazoleFor the treatment of esophageal candidiasis, invasive pulmonary aspergillosis, and serious fungal infections caused by Scedosporium apiospermum and Fusarium spp.
DB00639ButoconazoleFor the local treatment of vulvovaginal candidiasis (infections caused by Candida)
DB00646NystatinFor treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species
DB00681Amphotericin BUsed to treat potentially life threatening fungal infections.
DB00735NaftifineFor the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum.
DB00738PentamidineFor the treatment of pneumonia due to Pneumocystis carinii.
DB00793HaloproginUsed to treat fungal (Tinea) skin infections such as athlete's foot, jock itch, ringworm, and tinea versicolor.
DB00826NatamycinFor the treatment of fungal blepharitis, conjunctivitis, and keratitis caused by susceptible organisms including Fusarium solani keratitis.
DB00857TerbinafineFor the treatment of dermatophyte infections of the toenail or fingernail caused by susceptible fungi. Also for the treatment of tinea capitis (scalp ringworm) and tinea corporis (body ringworm) or tinea cruris (jock itch).
DB00877SirolimusFor the prophylaxis of organ rejection in patients receiving renal transplants.
DB00936Salicylic acidKey additive in many skin-care products for the treatment of acne, psoriasis, callouses, corns, keratosis pilaris and warts.
DB01007TioconazoleFor the local treatment of vulvovaginal candidiasis (moniliasis).
DB01026KetoconazoleFor the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.
DB01034CeruleninFor use as a biochemical tool, Cerulenin is shown to cause dramatic weight loss in animals
DB01091ButenafineFor the topical treatment of the following dermatologic infections: tinea (pityriasis) versicolor due to M. furfur, interdigital tinea pedis (athlete’s foot), tinea corporis (ringworm) and tinea cruris (jock itch) due to E. floccosum, T. mentagrophytes, T. rubrum, and T. tonsurans.
DB01099FlucytosineFor the treatment (in combination with amphotericin B) of serious infections caused by susceptible strains of Candida (septicemia, endocarditis and urinary system infections) and/or Cryptococcus (meningitis and pulmonary infections).
DB01110MiconazoleFor topical application in the treatment of tinea pedis (athlete’s foot), tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis (moniliasis), and in the treatment of tinea versicolor.
DB01127EconazoleFor topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Microsporum gypseum, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis, and in the treatment of tinea versicolor.
DB01141MicafunginFor use in the treatment of candidemia, acute disseminated candidiasis, and certain other invasive Candida infections, as well as esophageal candidiasis, and prophylaxis of Candida infections in patients undergoing hematopoietic stem cell transplantation. Micafungin is also used as an alternative for the treatment of oropharyngeal candidiases and has been used with some success as primary or salvage therapy, alone or in combination with other antifungals, for the treatment of invasive aspergillosis.
DB01152CandicidinUsed in the topical treatment of vulvovaginal candidiasis.
DB01153SertaconazoleFor the topical treatment of interdigital tinea pedis in immunocompetent patients 12 years of age and older, caused by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum.
DB01167ItraconazoleFor the treatment of the following fungal infections in immunocompromised and non-immunocompromised patients: pulmonary and extrapulmonary blastomycosis, histoplasmosis, aspergillosis, and onychomycosis.
DB01188CiclopiroxUsed as a topical treatment in immunocompetent patients with mild to moderate onychomycosis of fingernails and toenails without lunula involvement, due to Trichophyton rubrum.
DB01243ChloroxineUsed in the treatment of dandruff and mild to moderately severe seborrheic dermatitis of the scalp.
DB01263PosaconazoleFor prophylaxis of invasive Aspergillus and Candida infections in patients, 13 years of age and older, who are at high risk of developing these infections due to being severely immunocompromised as a result of procedures such as hematopoietic stem cell transplant (HSCT) recipients with graft-versus-host disease (GVHD), or due to hematologic malignancies with prolonged neutropenia from chemotherapy. Also for the treatment of oropharyngeal candidiasis, including oropharyngeal candidiasis refractory to itraconazole and/or fluconazole. Posaconazole is used as an alternative treatment for invasive aspergillosis, Fusarium infections, and zygomycosis in patients who are intolerant of, or whose disease is refractory to, other antifungals.
DB01422NitroxolineNitroxoline is an antibiotic agent.
DB01910SinefunginNot Available
DB02513ThymolNot Available
DB03758RadicicolNot Available
DB03793Benzoic AcidNot Available
DB03819Salicylhydroxamic AcidNot Available
DB04741MyxothiazolNot Available
DB04744LawsoneNot Available
DB04794BifonazoleUsed for the treatment of various topical fungal infections, including athlete's foot (tinea pedis).
DB06693MevastatinNot used therapeutically due to its many side effects.
DB06733Bafilomycin A1Not Available
DB06820SulconazoleSulconazole solution 1.0% is indicated for the treatment of tinea cruris and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, and Microsporum canis; and for the treatment of tinea versicolor. Effectiveness has not been proven in tinea pedis (athlete’s foot).
DB08943IsoconazoleNot Available
DB08958HexetidineNot Available
DB09031MiltefosineFor the treatment of mucosal (caused by Leishmania braziliensis), cutaneous (caused by L. braziliensis, L. guyanensis, and L. panamensis), and visceral leishmaniasis (caused by L. donovani). In comparing Leishmania drug susceptibility, it has been found that L. donovani is the most susceptible to miltefosine while L. major is the least susceptible. Off-label use includes treatment of free-living amebae (FLA) infections (unlabeled use; CDC, 2013).
DB09040EfinaconazoleIndicated in the treatment of fungal infection of the nail, known as onychomycosis.
DB09041TavaboroleIndicated for the treatment of onychomycosis (a fungal infection) of the toenails due to Trichophyton rubrum or Trichophyton mentagrophytes.
DB09056AmorolfineNot Available
DB12156CordycepinNot Available
DB12939Nikkomycin ZNot Available
DB08059WortmanninNot Available
DB00091CyclosporineFor treatment of transplant (kidney, liver, and heart) rejection, rheumatoid arthritis, severe psoriasis.
DB03600Capric acidNot Available
DB12073AlbaconazoleNot Available
DB11633Isavuconazole- Indicated for patients 18 years of age and older for the treatment of invasive aspergillosis [FDA Label]. - Indicated for patients 18 years of age and older for the treatment of invasive mucormycosis [FDA Label], including patients where treatment amphotericin B is inappropriate [L1482].
DB06440RavuconazoleInvestigated for use/treatment in fungal infections, aspergillosis, candidiasis, and onychomycosis.
DB06395AbafunginInvestigated for use/treatment in fungal infections, bacterial infection, skin infections/disorders, and onychomycosis.
DB06636IsavuconazoniumIndicated in the treatment of invasive aspergillosis and invasive mucormycosis.
DB08933LuliconazoleLuliconazole is indicated in adults aged 18 years and older for the topical treatment of fungal infections caused by Trichophyton rubrum and Epidermophyton floccosum, specifically tinea pedis, cruris, and corporis.
DB14058BasifunginNot Available
DB06815PyrithioneIndicated for the treatment of dandruff and seborrheic dermatitis [A27133].
DB02756PyroquilonNot Available
DrugDrug NameTargetType
DB00196FluconazoleCytochrome P450 3A4enzyme
DB00196FluconazoleCytochrome P450 2C9enzyme
DB00196FluconazoleCytochrome P450 2C19enzyme
DB00196FluconazoleCytochrome P450 3A5enzyme
DB00196FluconazoleCytochrome P450 3A7enzyme
DB00196FluconazoleCytochrome P450 11B1, mitochondrialenzyme
DB00196FluconazoleLanosterol 14-alpha demethylasetarget
DB00196FluconazoleMultidrug resistance protein 1transporter
DB00239OxiconazoleCytochrome P450 3A4enzyme
DB00239OxiconazoleCytochrome P450 2C19enzyme
DB00239OxiconazoleLanosterol 14-alpha demethylasetarget
DB00239OxiconazoleLanosterol synthasetarget
DB00239OxiconazoleNuclear receptor subfamily 1 group I member 2target
DB00251TerconazoleLanosterol 14-alpha demethylasetarget
DB00257ClotrimazoleCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB00257ClotrimazoleCytochrome P450 2D6enzyme
DB00257ClotrimazoleCytochrome P450 2C8enzyme
DB00257ClotrimazoleCytochrome P450 3A4enzyme
DB00257ClotrimazoleCytochrome P450 2B6enzyme
DB00257ClotrimazoleCytochrome P450 11B1, mitochondrialenzyme
DB00257ClotrimazoleCytochrome P450 19A1enzyme
DB00257ClotrimazoleCytochrome P450 2A6enzyme
DB00257ClotrimazoleCytochrome P450 2C9enzyme
DB00257ClotrimazoleCytochrome P450 2E1enzyme
DB00257ClotrimazoleCytochrome P450 3A7enzyme
DB00257ClotrimazoleIntermediate conductance calcium-activated potassium channel protein 4target
DB00257ClotrimazoleLanosterol 14-alpha demethylasetarget
DB00257ClotrimazoleNuclear receptor subfamily 1 group I member 2target
DB00257ClotrimazoleNuclear receptor subfamily 1 group I member 3target
DB00257ClotrimazoleCanalicular multispecific organic anion transporter 2transporter
DB00257ClotrimazoleMultidrug resistance protein 1transporter
DB00257ClotrimazoleCanalicular multispecific organic anion transporter 1transporter
DB00257ClotrimazoleBile salt export pumptransporter
DB00362Anidulafungin1,3-beta-glucan synthase component FKS1target
DB00400GriseofulvinCytochrome P450 1A2enzyme
DB00400GriseofulvinCytochrome P450 3A4enzyme
DB00400GriseofulvinCytochrome P450 2D6enzyme
DB00400GriseofulvinTubulin beta chaintarget
DB00400GriseofulvinTubulin alpha chaintarget
DB00400GriseofulvinKeratin, type I cytoskeletal 12target
DB00520CaspofunginCytochrome P450 3A4enzyme
DB00520Caspofungin1,3-beta-glucan synthase component FKS1target
DB00520CaspofunginSolute carrier family 22 member 1transporter
DB00520CaspofunginMultidrug resistance protein 1transporter
DB00520CaspofunginSolute carrier family 22 member 6transporter
DB00520CaspofunginSolute carrier organic anion transporter family member 1B1transporter
DB00520CaspofunginSolute carrier organic anion transporter family member 1B3transporter
DB00525TolnaftateSqualene monooxygenasetarget
DB00582VoriconazoleCytochrome P450 2C19enzyme
DB00582VoriconazoleCytochrome P450 3A4enzyme
DB00582VoriconazoleCytochrome P450 2C9enzyme
DB00582VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00582VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00582VoriconazoleCytochrome P450 3A5enzyme
DB00582VoriconazoleCytochrome P450 3A7enzyme
DB00582VoriconazoleProstaglandin G/H synthase 1enzyme
DB00582VoriconazoleCytochrome P450 2B6enzyme
DB00582VoriconazoleLanosterol 14-alpha demethylasetarget
DB00639ButoconazoleErgosteroltarget
DB00646NystatinCytochrome P450 3A4enzyme
DB00646NystatinErgosteroltarget
DB00646NystatinSolute carrier organic anion transporter family member 1B1transporter
DB00646NystatinSolute carrier organic anion transporter family member 1B3transporter
DB00681Amphotericin BCytochrome P450 3A4enzyme
DB00681Amphotericin BErgosteroltarget
DB00735NaftifineSqualene monooxygenasetarget
DB00738PentamidineCytochrome P450 2C19enzyme
DB00738PentamidineCytochrome P450 2C8enzyme
DB00738PentamidineCytochrome P450 2D6enzyme
DB00738PentamidineCytochrome P450 1A1enzyme
DB00738PentamidineCytochrome P450 3A5enzyme
DB00738PentamidineCytochrome P450 4A11enzyme
DB00738PentamidineDNAtarget
DB00738PentamidinetRNA (cytosine(38)-C(5))-methyltransferasetarget
DB00826NatamycinCytochrome P450 3A4enzyme
DB00826NatamycinErgosteroltarget
DB00857TerbinafineCytochrome P450 2D6enzyme
DB00857TerbinafineCytochrome P450 2C9enzyme
DB00857TerbinafineCytochrome P450 1A2enzyme
DB00857TerbinafineCytochrome P450 3A4enzyme
DB00857TerbinafineCytochrome P450 2C8enzyme
DB00857TerbinafineCytochrome P450 2C19enzyme
DB00857TerbinafineProstaglandin G/H synthase 1enzyme
DB00857TerbinafineCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB00857TerbinafineCytochrome P450 19A1enzyme
DB00857TerbinafineSqualene monooxygenasetarget
DB00877SirolimusCytochrome P450 3A4enzyme
DB00877SirolimusCytochrome P450 3A5enzyme
DB00877SirolimusCytochrome P450 3A7enzyme
DB00877SirolimusPeptidyl-prolyl cis-trans isomerase FKBP1Atarget
DB00877SirolimusSerine/threonine-protein kinase mTORtarget
DB00877SirolimusFibroblast growth factor 2target
DB00877SirolimusMultidrug resistance protein 1transporter
DB00877SirolimusSolute carrier organic anion transporter family member 1B1transporter
DB00877SirolimusMultidrug and toxin extrusion protein 1transporter
DB00936Salicylic acidSerum albumincarrier
DB00936Salicylic acidCytochrome P450 2C9enzyme
DB00936Salicylic acidProstaglandin G/H synthase 1target
DB00936Salicylic acidProstaglandin G/H synthase 2target
DB00936Salicylic acidAldo-keto reductase family 1 member C1target
DB00936Salicylic acidSolute carrier family 22 member 6transporter
DB00936Salicylic acidSolute carrier family 22 member 10transporter
DB00936Salicylic acidSolute carrier family 22 member 8transporter
DB00936Salicylic acidSolute carrier family 22 member 11transporter
DB00936Salicylic acidSolute carrier organic anion transporter family member 2B1transporter
DB00936Salicylic acidMonocarboxylate transporter 1transporter
DB00936Salicylic acidSolute carrier family 22 member 7transporter
DB01007TioconazoleCytochrome P450 19A1enzyme
DB01007TioconazoleCytochrome P450 2C19enzyme
DB01007TioconazoleCytochrome P450 2C8enzyme
DB01007TioconazoleCytochrome P450 2E1enzyme
DB01007TioconazoleCytochrome P450 3A4enzyme
DB01007TioconazoleLanosterol 14-alpha demethylasetarget
DB01007TioconazoleLanosterol 14-alpha demethylasetarget
DB01026KetoconazoleCytochrome P450 3A4enzyme
DB01026KetoconazoleCytochrome P450 2C9enzyme
DB01026KetoconazoleCytochrome P450 2C19enzyme
DB01026KetoconazoleCytochrome P450 3A5enzyme
DB01026KetoconazoleCytochrome P450 1A2enzyme
DB01026KetoconazoleCytochrome P450 2C8enzyme
DB01026KetoconazoleCytochrome P450 1A1enzyme
DB01026KetoconazoleCytochrome P450 2D6enzyme
DB01026KetoconazoleCytochrome P450 3A7enzyme
DB01026KetoconazoleCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB01026KetoconazoleCytochrome P450 11B1, mitochondrialenzyme
DB01026KetoconazoleCytochrome P450 1B1enzyme
DB01026KetoconazoleCytochrome P450 26A1enzyme
DB01026KetoconazoleCytochrome P450 2A6enzyme
DB01026KetoconazoleCytochrome P450 2B6enzyme
DB01026KetoconazoleLanosterol 14-alpha demethylaseenzyme
DB01026KetoconazoleUDP-glucuronosyltransferase 1-1enzyme
DB01026KetoconazoleUDP-glucuronosyltransferase 2B7enzyme
DB01026KetoconazoleCytochrome P450 4F12enzyme
DB01026KetoconazoleLeukotriene-B(4) omega-hydroxylase 1enzyme
DB01026KetoconazoleLanosterol 14-alpha demethylasetarget
DB01026KetoconazoleAndrogen receptortarget
DB01026Ketoconazole17-hydroxylasetarget
DB01026KetoconazoleSteroid 21-hydroxylasetarget
DB01026Ketoconazole11-hydroxylasetarget
DB01026KetoconazoleCytochrome P450 19A1target
DB01026KetoconazolePotassium voltage-gated channel subfamily H member 2target
DB01026KetoconazoleNuclear receptor subfamily 1 group I member 2target
DB01026KetoconazoleNuclear receptor subfamily 1 group I member 3target
DB01026KetoconazoleBile salt export pumptransporter
DB01026KetoconazoleMultidrug resistance protein 1transporter
DB01026KetoconazoleSolute carrier organic anion transporter family member 1A2transporter
DB01026KetoconazoleSolute carrier organic anion transporter family member 1B1transporter
DB01034Cerulenin3-oxoacyl-[acyl-carrier-protein] synthase 3target
DB01034Cerulenin3-oxoacyl-[acyl-carrier-protein] synthase 2target
DB01034Cerulenin3-oxoacyl-[acyl-carrier-protein] synthase 1target
DB01034CeruleninFatty acid synthasetarget
DB01091ButenafineSqualene monooxygenasetarget
DB01099FlucytosineThymidylate synthasetarget
DB01099FlucytosineDNA (cytosine-5)-methyltransferase 1target
DB01099FlucytosineDNAtarget
DB01110MiconazoleCytochrome P450 2C9enzyme
DB01110MiconazoleCytochrome P450 2D6enzyme
DB01110MiconazoleCytochrome P450 3A4enzyme
DB01110MiconazoleCytochrome P450 11B1, mitochondrialenzyme
DB01110MiconazoleCytochrome P450 2A6enzyme
DB01110MiconazoleCytochrome P450 2B6enzyme
DB01110MiconazoleCytochrome P450 2C19enzyme
DB01110MiconazoleCytochrome P450 2E1enzyme
DB01110MiconazoleLanosterol 14-alpha demethylaseenzyme
DB01110MiconazoleCytochrome P450 19A1enzyme
DB01110MiconazoleLanosterol 14-alpha demethylasetarget
DB01110MiconazoleNitric oxide synthase, endothelialtarget
DB01110MiconazoleNitric oxide synthase, inducibletarget
DB01110MiconazoleCalcium-activated potassium channel subunit alpha-1target
DB01110MiconazoleCalcium-activated potassium channel subunit beta-1target
DB01110MiconazoleCalcium-activated potassium channel subunit beta-2target
DB01110MiconazoleCalcium-activated potassium channel subunit beta-3target
DB01110MiconazoleCalcium-activated potassium channel subunit beta-4target
DB01110MiconazoleIntermediate conductance calcium-activated potassium channel protein 4target
DB01110MiconazoleSmall conductance calcium-activated potassium channel protein 1target
DB01110MiconazoleSmall conductance calcium-activated potassium channel protein 2target
DB01110MiconazoleSmall conductance calcium-activated potassium channel protein 3target
DB01110MiconazolePotassium voltage-gated channel subfamily H member 2target
DB01110MiconazolePotassium voltage-gated channel subfamily H member 6target
DB01110MiconazolePotassium voltage-gated channel subfamily H member 7target
DB01110MiconazoleNuclear receptor subfamily 1 group I member 2target
DB01110MiconazoleMultidrug resistance protein 1transporter
DB01127EconazoleCytochrome P450 19A1enzyme
DB01127EconazoleCytochrome P450 2E1enzyme
DB01127EconazoleCytochrome P450 3A4enzyme
DB01127EconazoleLanosterol 14-alpha demethylasetarget
DB01127EconazoleNuclear receptor subfamily 1 group I member 2target
DB01141MicafunginArylsulfatase Aenzyme
DB01141MicafunginCatechol O-methyltransferaseenzyme
DB01141Micafungin1,3-beta-glucan synthase component FKS1target
DB01152CandicidinCytochrome P450 3A4enzyme
DB01152CandicidinErgosteroltarget
DB01153SertaconazoleLanosterol 14-alpha demethylaseenzyme
DB01153SertaconazoleLanosterol 14-alpha demethylasetarget
DB01167ItraconazoleCytochrome P450 3A4enzyme
DB01167ItraconazoleCytochrome P450 2D6enzyme
DB01167ItraconazoleCytochrome P450 3A5enzyme
DB01167ItraconazoleCytochrome P450 3A7enzyme
DB01167ItraconazoleCytochrome P450 2B6enzyme
DB01167ItraconazoleCytochrome P450 1A1enzyme
DB01167ItraconazoleCytochrome P450 2E1enzyme
DB01167ItraconazoleLanosterol 14-alpha demethylasetarget
DB01167ItraconazoleLanosterol 14-alpha demethylasetarget
DB01167ItraconazoleMultidrug resistance protein 1transporter
DB01167ItraconazoleSolute carrier organic anion transporter family member 2B1transporter
DB01188CiclopiroxSodium/potassium-transporting ATPase subunit alpha-1target
DB01263PosaconazoleCytochrome P450 3A4enzyme
DB01263PosaconazoleLanosterol 14-alpha demethylasetarget
DB01263PosaconazoleMultidrug resistance protein 1transporter
DB01422NitroxolineMethionine aminopeptidase 2target
DB01422NitroxolineMagnesium cationtarget
DB01422NitroxolineManganese cationtarget
DB01910SinefunginModification methylase RsrItarget
DB01910SinefunginRdmBtarget
DB01910SinefunginrRNA adenine N-6-methyltransferasetarget
DB01910SinefunginModification methylase TaqItarget
DB03758RadicicolHeat shock protein HSP 90-betatarget
DB03758RadicicolEndoplasmintarget
DB03758RadicicolDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrialtarget
DB03758Radicicol[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrialtarget
DB03758RadicicolVirulence sensor histidine kinase PhoQtarget
DB03793Benzoic AcidPeroxiredoxin-5, mitochondrialtarget
DB03793Benzoic AcidHeat-labile enterotoxin B chaintarget
DB03793Benzoic AcidCocaine esterasetarget
DB03793Benzoic AcidHTH-type transcriptional regulator MalTtarget
DB03793Benzoic AcidTautomerase PptAtarget
DB03793Benzoic AcidD-amino-acid oxidasetarget
DB03793Benzoic AcidRibonuclease UK114target
DB03793Benzoic AcidChlorocatechol 1,2-dioxygenasetarget
DB03793Benzoic AcidRas-related protein Rab-9Atarget
DB03793Benzoic AcidHydrogen peroxide-inducible genes activatortarget
DB03793Benzoic Acid2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolasetarget
DB03793Benzoic AcidNon-heme chloroperoxidasetarget
DB03793Benzoic AcidOxygen-insensitive NAD(P)H nitroreductasetarget
DB03793Benzoic AcidHydroxyquinol 1,2-dioxygenasetarget
DB03793Benzoic AcidReplication proteintarget
DB03793Benzoic AcidSolute carrier family 15 member 1target
DB03793Benzoic AcidSolute carrier organic anion transporter family member 2B1transporter
DB03793Benzoic AcidSolute carrier family 22 member 8transporter
DB03793Benzoic AcidMonocarboxylate transporter 1transporter
DB04741MyxothiazolCytochrome b-c1 complex subunit 1, mitochondrialtarget
DB04794BifonazoleCytochrome P450 19A1enzyme
DB04794BifonazoleCytochrome P450 2E1enzyme
DB04794BifonazoleCytochrome P450 3A4enzyme
DB04794BifonazoleCytochrome P450 2B6target
DB04794BifonazoleLanosterol 14-alpha demethylasetarget
DB06693MevastatinLiver carboxylesterase 1enzyme
DB06693Mevastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB06733Bafilomycin A1V-type proton ATPase catalytic subunit Atarget
DB06820SulconazoleCytochrome P450 1A2enzyme
DB06820SulconazoleCytochrome P450 2C9enzyme
DB06820SulconazoleCytochrome P450 2D6enzyme
DB09031MiltefosinePhospholipase D1enzyme
DB09031MiltefosineMultidrug resistance protein 1target
DB09040EfinaconazoleLanosterol 14-alpha demethylasetarget
DB09041TavaboroleCytosolic leucyl-tRNA synthetasetarget
DB08059WortmanninPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
DB08059WortmanninSerine/threonine-protein kinase PLK1target
DB08059WortmanninPhosphatidylinositol 3-kinase regulatory subunit alphatarget
DB08059WortmanninPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
DB00091CyclosporineCytochrome P450 3A5enzyme
DB00091CyclosporineCytochrome P450 3A4enzyme
DB00091CyclosporineCytochrome P450 3A7enzyme
DB00091CyclosporineCytochrome P450 2C19enzyme
DB00091CyclosporineCytochrome P450 2C8enzyme
DB00091CyclosporineCytochrome P450 2C9enzyme
DB00091CyclosporineCytochrome P450 2D6enzyme
DB00091CyclosporineCalcium signal-modulating cyclophilin ligandtarget
DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase Atarget
DB00091CyclosporineCalcineurin subunit B type 2target
DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
DB00091CyclosporineMultidrug resistance protein 1transporter
DB00091CyclosporineCanalicular multispecific organic anion transporter 2transporter
DB00091CyclosporineBile salt export pumptransporter
DB00091CyclosporineMultidrug resistance-associated protein 1transporter
DB00091CyclosporineSolute carrier organic anion transporter family member 1A2transporter
DB00091CyclosporineIleal sodium/bile acid cotransportertransporter
DB00091CyclosporineSodium/bile acid cotransportertransporter
DB00091CyclosporineSolute carrier family 22 member 6transporter
DB00091CyclosporineMultidrug resistance-associated protein 7transporter
DB00091CyclosporineCanalicular multispecific organic anion transporter 1transporter
DB00091CyclosporineATP-binding cassette sub-family G member 2transporter
DB00091CyclosporineSolute carrier organic anion transporter family member 1B1transporter
DB00091CyclosporineSolute carrier organic anion transporter family member 1B3transporter
DB03600Capric acidSerum albumincarrier
DB03600Capric acid3-oxoacyl-[acyl-carrier-protein] synthase 1target
DB03600Capric acidFurintarget
DB03600Capric acidPeptostreptococcal albumin-binding proteintarget
DB03600Capric acidGlycolipid transfer proteintarget
DB03600Capric acidOctanoyltransferasetarget
DB03600Capric acidPutative uncharacterized protein tcp14target
DB03600Capric acidPeroxisome proliferator-activated receptor gammatarget
DB11633IsavuconazoleCytochrome P450 3A4enzyme
DB11633IsavuconazoleCytochrome P450 3A5enzyme
DB11633IsavuconazoleCytochrome P450 2C8enzyme
DB11633IsavuconazoleCytochrome P450 2C9enzyme
DB11633IsavuconazoleCytochrome P450 2C19enzyme
DB11633IsavuconazoleCytochrome P450 2D6enzyme
DB11633IsavuconazoleCytochrome P450 2B6enzyme
DB11633IsavuconazoleUDP-glucuronosyltransferase 1-9enzyme
DB11633IsavuconazoleUDP-glucuronosyltransferase 1-8enzyme
DB11633IsavuconazoleLanosterol 14-alpha demethylasetarget
DB11633IsavuconazolePotassium voltage-gated channel subfamily H member 2target
DB11633IsavuconazoleVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB11633IsavuconazoleG protein-activated inward rectifier potassium channel 2target
DB11633IsavuconazoleG protein-activated inward rectifier potassium channel 3target
DB11633IsavuconazoleATP-sensitive inward rectifier potassium channel 11target
DB11633IsavuconazolePotassium voltage-gated channel subfamily A member 5target
DB11633IsavuconazolePotassium voltage-gated channel subfamily D member 3target
DB11633IsavuconazolePotassium voltage-gated channel subfamily KQT member 1target
DB11633IsavuconazoleSodium channel protein type 5 subunit alphatarget
DB11633IsavuconazoleMultidrug resistance protein 1transporter
DB11633IsavuconazoleATP-binding cassette sub-family G member 2transporter
DB11633IsavuconazoleSolute carrier family 22 member 2transporter
DB06636IsavuconazoniumCytochrome P450 3A4enzyme
DB06636IsavuconazoniumMultidrug resistance protein 1transporter
DB08933LuliconazoleCytochrome P450 3A4enzyme
DB08933LuliconazoleCytochrome P450 2C19enzyme
DB08933LuliconazoleLanosterol 14-alpha demethylasetarget
DB14058BasifunginInositol phosphorylceramide synthasetarget