- Accession Number
- DBCAT001927 (DBCAT001403, DBCAT003703)
Agents that produce a soft formed stool, stimulate intestinal motility, or otherwise promote emptying of the bowel. Typically used to relieve CONSTIPATION or to prepare the bowel for surgical procedures.
Drug Drug Description Sorbitol A product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener. Dantron Withdrawn from the Canadian, US, and UK markets in 1998 due to genotoxicity. Oxyphenisatin A laxative that undergoes enterohepatic circulation. It may cause jaundice. Bisacodyl A stimulant laxative used for the temporary relief of occasional constipation and cleansing of the colon as a preparation for colonoscopy in adults. Picosulfuric acid A stimulant laxative used for cleansing of the colon as a preparation for colonoscopy in adults. Polyethylene glycol A laxative used to treat constipation and used for bowel preparation before colonoscopies and other procedures. Polycarbophil Polycarbophil is used to treat constipation and to help maintain regular bowel movements. Sodium sulfate An agent used for bowel cleansing prior to colonoscopy or barium enema X-ray examination. Carboxymethylcellulose A compound used as an ophthalmic lubricant. Plantago seed An ingredient used in a variety of natural health products. Castor oil An ingredient used in a variety of natural health products. Sennosides A laxative used to treat constipation. Lactitol An orally administered osmotic laxative used to treat chronic idiopathic constipation. Lactulose A disaccharide derivative of lactose used to treat constipation and portal systemic encephalopathy. Glycerin It is used as a solvent, emollient, pharmaceutical agent, and sweetening agent. Mineral oil Mineral oil is not considered an active pharmacological ingredient in pharmaceutical preparations and so has no official indication. It is typically present in topical formulations as an emollient and occlusive... Docusate A medication used to treat constipation associated with dry, hard stools, or opioid induced constipation. Methylcellulose A compound used as a bulk forming laxative and is not an approved medication. Magnesium citrate A laxative used in bowel preparation for colonoscopy or as a magnesium supplement. Magnesium hydroxide An inorganic compound used as a laxative and antacid. Magnesium oxide A compound commonly used as a laxative for the symptomatic relief of acid indigestion and upset stomach, and in health supplements for cardiovascular and neuromuscular health. Magnesium sulfate A drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany. Magnesium carbonate An antacid used for symptomatic relief of heartburn, indigestion, and upset stomach. Pentaerithrityl Not Annotated Sodium tartrate It acts as an emulsifier and pH control agent in food products , . In the laboratory, it is used while performing the Karl Fischer equation, which is used to... Mannitol A sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, and to measure glomerular filtration rate. Sodium phosphate, monobasic A source of phosphorus used prevent or correct hypophosphatemia in patients with restricted or no oral intake. Magnesium peroxide Not Annotated Phenolphthalein Used for over a century as a laxative. Bisoxatin For use in the treatment of constipation in the absence of bowel obstruction and for surgical preparation of the colon . Lubiprostone A prostaglandin derivative used to treat constipation caused by irritable bowel syndrome and opioid-use. Linaclotide A guanylate cyclase-C agonist used to treat constipation associated with irritable bowel syndrome or that is idiopathic in nature. Prucalopride A P2Y12 platelet receptor antagonist used during percutaneous coronary intervention to reduce the risk for periprocedural myocardial infarction (MI), repeat coronary revascularization, and stent thrombosis (ST). Tegaserod A serotonin-4 (5-HT4) receptor agonist indicated for the treatment of constipation predominant irritable bowel syndrome (IBS-C) specifically in women under the age of 65. There is currently no safety or efficacy data for use of tegaserol in men. Plecanatide A laxative used to treat chronic idiopathic constipation and IBS with constipation. Deacetylbisacodyl Not Annotated Magnesium cation Magnesium hydroxide is used primarily in "Milk of Magnesia", a white aqueous, mildly alkaline suspension of magnesium hydroxide formulated at about 8%w/v. Milk of magnesia is primarily used to alleviate... Zinc An essential element commonly used for the treatment of patients with documented zinc deficiency. Sodium cation Not Annotated Sulfate ion Not Annotated Plantago ovata seed Not Annotated Phenylacetic acid An agent used as an adjunct to treat acute hyperammonemia and associated encephalopathy in adult and pediatric patients with deficiencies in enzymes of the urea cycle. Magnesium trisilicate An antacid used for the symptomatic treatment of peptic ulcers. Magnesium acetate tetrahydrate An ionic compound used for electrolyte replenishment and total parenteral nutrition (TPN) therapy. Monopotassium phosphate An ionic compound used for electrolyte replenishment and total parenteral nutrition (TPN) therapy. Dipotassium phosphate An ionic compound used for electrolyte replenishment and total parenteral nutrition (TPN) therapy. Sodium fluorophosphate A fluoride anticaries agent used to prevent and treat dental cavities. Magnesium glycinate Magnesium glycinate is a magnesium salt of glycine that is available as dietary supplements as a source of magnesium. It is used in the treatment of magnesium deficiency. Gluconic Acid An electrolyte supplement used in total parenteral nutrition. Sodium aurotiosulfate Not Annotated Magnesium acetate Not Available Sodium ascorbate Not Available Potassium sulfate An osmotic laxative used to cleanse the colon before a colonoscopy. Sodium phosphate, dibasic An osmotic laxative used to cleanse the colon before a colonoscopy. Sodium phosphate, monobasic, unspecified form An osmotic laxative used to cleanse the colon before a colonoscopy. Sodium phosphate, dibasic, unspecified form An osmotic laxative used to cleanse the colon before a colonoscopy. Magnesium A medication used for many purposes including constipation, indigestion, magnesium deficiency, and pre-eclampsia. Oxyphenisatin acetate Not Annotated Calcium polycarbophil A bulk forming laxative used to treat constipation. Emodin Emodin has been investigated for the treatment of Polycystic Kidney. Konjac mannan Konjac mannan is under investigation in clinical trial NCT01709955 (The Effects of Glucomannan on Weight Loss). Potassium lactate Not Annotated Alloin Not Annotated Frangula purshiana bark Not Annotated Dehydrocholic acid No approved therapeutic indications. Karaya gum An extract from Karaya gum used in allergy testing.
- Drugs & Drug Targets