Constipation

Also known as: Constipations / Constipation, unspecified / Constipation (& symptom)

DrugDrug NameDrug Description
DB09020BisacodylA stimulant laxative used for the temporary relief of occasional constipation and cleansing of the colon as a preparation for colonoscopy in adults.
DB11089DocusateA medication used to treat constipation associated with dry, hard stools, or opioid induced constipation.
DB09462GlycerinIt is used as a solvent, emollient, pharmaceutical agent, and sweetening agent.
DB00581LactuloseA disaccharide derivative of lactose used to treat constipation and portal systemic encephalopathy.
DB01046LubiprostoneA prostaglandin derivative used to treat constipation caused by irritable bowel syndrome and opioid-use.
DB09104Magnesium hydroxideAn inorganic compound used as a laxative and antacid.
DB00653Magnesium sulfateA drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany.
DB11228MethylcelluloseA compound used as a bulk forming laxative and is not an approved medication.
DB09287Polyethylene glycolA laxative used to treat constipation and used for bowel preparation before colonoscopies and other procedures.
DB00545PyridostigmineA cholinesterase inhibitor used to treat myasthenia gravis.
DB11365SennosidesA laxative used to treat constipation.
DB13157Sodium lauryl sulfoacetateSodium lauryl sulfoacetate is not an active pharmacological ingredient in pharmaceutical preparations and so has no official indication.
DB14503Sodium phosphate, monobasic, unspecified formAn osmotic laxative used to cleanse the colon before a colonoscopy.
DB01638SorbitolA product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener.
DrugDrug NameTargetType
DB09462GlycerinGroup IIE secretory phospholipase A2target
DB09462GlycerinInositol-3-phosphate synthase 1target
DB09462GlycerinAlcohol dehydrogenase 1Btarget
DB09462GlycerinInositol 1,4,5-trisphosphate receptor type 1target
DB09462GlycerinGlycodelintarget
DB09462GlycerinAlpha-N-acetylgalactosaminidasetarget
DB09462GlycerinADP-ribosylation factor 1target
DB09462GlycerinBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1target
DB09462GlycerinDNA mismatch repair protein MutLtarget
DB09462GlycerinRibonucleoside-diphosphate reductase 1 subunit betatarget
DB09462GlycerinA/G-specific adenine glycosylasetarget
DB09462GlycerintRNA (cytosine(38)-C(5))-methyltransferasetarget
DB09462GlycerinCytochrome P450 2E1enzyme
DB09462GlycerinRetinal dehydrogenase 1enzyme
DB09462GlycerinPeroxisome proliferator-activated receptor deltatarget
DB09462GlycerinMaleylacetoacetate isomerasetarget
DB09462GlycerinAquaporin-7transporter
DB09462GlycerinAquaporin-9transporter
DB09462GlycerinGlycerol uptake facilitator proteintransporter
DB00581LactuloseEvolved beta-galactosidase subunit alphatarget
DB01046LubiprostoneChloride channel protein 2target
DB01046LubiprostoneCarbonyl reductase [NADPH] 1enzyme
DB00653Magnesium sulfateVoltage-dependent L-type calcium channeltarget
DB09287Polyethylene glycolP-glycoprotein 1transporter
DB00545PyridostigmineAcetylcholinesterasetarget
DB00545PyridostigmineCholinesterasetarget
DB00545PyridostigmineSerum albumintarget
DB11365SennosidesReverse transcriptase/RNaseHtarget
DB11365SennosidesAquaporin-3target
DB14503Sodium phosphate, monobasic, unspecified formSodium-dependent phosphate transporter 1transporter
DB14503Sodium phosphate, monobasic, unspecified formSodium-dependent phosphate transporter 2transporter
DB14503Sodium phosphate, monobasic, unspecified formSodium-dependent phosphate transport protein 2Atransporter
DB14503Sodium phosphate, monobasic, unspecified formSodium-dependent phosphate transport protein 2Btransporter
DB14503Sodium phosphate, monobasic, unspecified formSodium-dependent phosphate transport protein 2Ctransporter
DrugDrug NamePhaseStatusCount
DB12013Axelopran1Completed1
DB08890Linaclotide1Completed1
DB12583Maltodextrin1Completed1
DB00218Moxifloxacin1Completed1
DB06480Prucalopride1Completed5
DB00545Pyridostigmine1 / 2Completed1
DB00346Alfuzosin2Completed1
DB06274Alvimopan2Completed1
DB06274Alvimopan2Terminated1
DB12464Bevenopran2Completed1
DB09020Bisacodyl2Completed1
DB09020Bisacodyl2Terminated1
DB11089Docusate2Recruiting1
DB13112Dolcanatide2Completed1
DB12486Elobixibat2Completed1
DB00898Ethanol2Completed1
DB09462Glycerin2Completed1
DB14811Isatuximab2Active Not Recruiting1
DB04924Itopride2Completed1
DB00581Lactulose2Completed1
DB08890Linaclotide2Completed1
DB06800Methylnaltrexone2Completed2
DB09049Naloxegol2Terminated1
DB01183Naloxone2Completed2
DB00497Oxycodone2Completed1
DB09287Polyethylene glycol2Completed2
DB09287Polyethylene glycol2Recruiting2
DB01839Propylene glycol2Recruiting1
DB06480Prucalopride2Completed5
DB12798Relenopride2Completed1
DB00512Vancomycin2Recruiting1
DB11089Docusate2 / 3Completed1
DB00327Hydromorphone2 / 3Completed1
DB01046Lubiprostone2 / 3Completed1
DB09049Naloxegol2 / 3Recruiting1
DB01183Naloxone2 / 3Completed1
DB11365Sennosides2 / 3Completed1
DB01079Tegaserod2 / 3Terminated1
DB06274Alvimopan3Completed3
DB09020Bisacodyl3Completed2
DB15648Calcium oxide3Completed1
DB01151Desipramine3Completed1
DB11089Docusate3Completed1
DB09462Glycerin3Completed1
DB08890Linaclotide3Completed1
DB01046Lubiprostone3Completed4
DB06800Methylnaltrexone3Completed3
DB11675Mosapride3Completed1
DB09049Naloxegol3Not Yet Recruiting1
DB01183Naloxone3Completed1
DB01183Naloxone3Terminated1
DB00497Oxycodone3Completed1
DB00497Oxycodone3Terminated1
DB11158Pectin3Completed1
DB09268Picosulfuric acid3Completed1
DB09287Polyethylene glycol3Completed1
DB09287Polyethylene glycol3Not Yet Recruiting1
DB09287Polyethylene glycol3Withdrawn1
DB00761Potassium chloride3Completed1
DB06480Prucalopride3Completed8
DB11365Sennosides3Completed2
DB11365Sennosides3Suspended1
DB09512Simethicone3Completed1
DB01390Sodium bicarbonate3Completed1
DB09153Sodium chloride3Completed1
DB01638Sorbitol3Completed1
DB02772Sucrose3Completed1
DB01079Tegaserod3Completed1
DB00316Acetaminophen4Completed1
DB00316Acetaminophen4Recruiting1
DB06274Alvimopan4Recruiting1
DB00181Baclofen4Terminated1
DB09020Bisacodyl4Completed3
DB09020Bisacodyl4Not Yet Recruiting2
DB09020Bisacodyl4Recruiting1
DB00297Bupivacaine4Recruiting1
DB00482Celecoxib4Completed1
DB01234Dexamethasone4Completed1
DB11089Docusate4Completed2
DB11089Docusate4Recruiting2
DB11089Docusate4Terminated1
DB00187Esmolol4Terminated1
DB00813Fentanyl4Recruiting1
DB00996Gabapentin4Completed1
DB00996Gabapentin4Recruiting1
DB00956Hydrocodone4Completed1
DB00956Hydrocodone4Recruiting1
DB00327Hydromorphone4Completed1
DB00327Hydromorphone4Recruiting1
DB01050Ibuprofen4Completed1
DB01221Ketamine4Recruiting1
DB00465Ketorolac4Recruiting1
DB00581Lactulose4Completed2
DB00581Lactulose4Recruiting2
DB00281Lidocaine4Recruiting1
DB00281Lidocaine4Terminated1
DB01046Lubiprostone4Completed4
DB01046Lubiprostone4Unknown Status1
DB11110Magnesium citrate4Recruiting1
DB09104Magnesium hydroxide4Completed1
DB00333Methadone4Recruiting1
DB06800Methylnaltrexone4Completed1
DB06800Methylnaltrexone4Recruiting1
DB00295Morphine4Recruiting1
DB09049Naloxegol4Recruiting1
DB09049Naloxegol4Terminated2
DB01183Naloxone4Completed1
DB01183Naloxone4Recruiting1
DB01183Naloxone4Terminated1
DB00104Octreotide4Completed1
DB00904Ondansetron4Completed1
DB01173Orphenadrine4Recruiting1
DB00497Oxycodone4Completed2
DB00497Oxycodone4Recruiting1
DB11097Plantago seed4Completed1
DB09287Polyethylene glycol4Completed4
DB09287Polyethylene glycol4Recruiting3
DB09287Polyethylene glycol4Terminated1
DB09287Polyethylene glycol4Unknown Status1
DB06480Prucalopride4Completed3
DB11365Sennosides4Completed1
DB11365Sennosides4Recruiting2
DB11365Sennosides4Terminated1
DB01638Sorbitol4Completed1
DB01079Tegaserod4Completed1
DB00193Tramadol4Recruiting1
DB00829DiazepamNot AvailableCompleted1
DB11089DocusateNot AvailableCompleted1
DB00581LactuloseNot AvailableUnknown Status2
DB01046LubiprostoneNot AvailableCompleted3
DB01046LubiprostoneNot AvailableTerminated1
DB06800MethylnaltrexoneNot AvailableTerminated1
DB11097Plantago seedNot AvailableCompleted1
DB09287Polyethylene glycolNot AvailableCompleted1
DB09287Polyethylene glycolNot AvailableTerminated1
DB06480PrucaloprideNot AvailableCompleted1
DB06480PrucaloprideNot AvailableWithdrawn1
DB11365SennosidesNot AvailableCompleted2
DB08839SerotoninNot AvailableCompleted1
DB01079TegaserodNot AvailableTerminated1
DB01079TegaserodNot AvailableUnknown Status1