Gastrointestinal Agents

Name
Gastrointestinal Agents
Accession Number
DBCAT000048
Description

Drugs used for their effects on the gastrointestinal system, as to control gastric acidity, regulate gastrointestinal motility and water flow, and improve digestion.

Drugs
DrugDrug Description
Glycine betaineA methyl group donor used for the treatment of homocystinuria to decrease elevated homocysteine blood levels.
Peppermint oilAn ingredient used in a variety of natural health products and is not an approved medication.
PancrelipaseA purified form of porcine pancreatic lipase, amylase, and protease enzymes used to treat malabsorption associated with pancreatic insufficiency resulting from cystic fibrosis and pancreatitis.
GlucagonA form of recombinant glucagon used to treat hypoglycemia in diabetes mellitus and as a part of gastrointestinal imaging procedures.
InfliximabA monoclonal anti tumor necrosis factor alpha antibody used in the treatment of a wide variety of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, and ankylosing spondylitis.
OctreotideA peptide drug used to treat acromegaly as well as diarrhea associated with metastatic carcinoid tumors and vasoactive intestinal peptide secreting tumors.
CholineA nutrient found in a wide variety of vitamins including pre-natal formulations.
LorazepamA long-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and seizures.
ErythromycinA macrolide antibiotic used to treat and prevent a variety of bacterial infections.
PantoprazoleA proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid.
BetazoleFor use clinically to test gastric secretory function.
OlanzapineAn antipsychotic drug used in the management of schizophrenia, bipolar 1 disorder, and agitation associated with these disorders.
OmeprazoleA proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection.
SucralfateA gastro-duodenal protective agent used in the treatment of gastric and duodenal ulcers and to prevent duodenal ulcer recurrence.
DoxylamineAn antihistamine used to treat insomnia and allergy symptoms and is used with pyridoxine in the treatment of nausea and vomiting in pregnancy.
ThiethylperazineFor the treatment or relief of nausea and vomiting.
PromazineA phenothiazine used to manage schizophrenia.
ProchlorperazineA phenothiazine derivative used in the treatment of schizophrenia and anxiety and to relieve severe nausea and vomiting.
CyproheptadineA serotonin and histamine antagonist used in the treatment of allergy symptoms and in combination with epinephrine in the treatment of anaphylaxis.
LansoprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
DroperidolA butyrophenone derivative and dopamine antagonist used to prevent and treat postoperative nausea and vomiting.
ChlorpromazineA phenothiazine antipsychotic used to treat nausea, vomiting, preoperative anxiety, schizophrenia, bipolar disorder, and severe behavioral problems in children.
NabiloneA synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy.
CimetidineA histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion.
HaloperidolAn antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium.
TriflupromazineUsed mainly in the management of psychoses. Also used to control nausea and vomiting.
LactuloseA disaccharide derivative of lactose used to treat constipation and portal systemic encephalopathy.
NizatidineAn H2 receptor antagonist used to treat GERD and a variety of ulcers.
CisaprideA medication used to treat heartburn associated with GERD.
TrimethobenzamideAn antiemetic used to treat postoperative nausea and vomiting and nausea associated with gastroenteritis.
PirenzepineAn antimuscarinic agent used to treat peptic ulcers, gastric ulcers, and duodenal ulcers.
AprepitantA substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery.
ApomorphineA morphine derivative D2 dopamine agonist used to treat hypomobile "off" episodes of advanced Parkinson's disease.
EsomeprazoleA proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion.
MeclizineA histamine H1 antagonist used to treat nausea, vomiting, and dizziness associated with motion sickness.
DolasetronAn antinauseant and antiemetic used in chemotherapy and postoperatively.
PropanthelineAn antimuscarinic agent used to treat urinary incontinence, hyperhidrosis, as well as cramps and spasms of the stomach, intestines, and bladder.
SulfasalazineAn anti-inflammatory drug used to treat Crohn's disease and rheumatoid arthritis.
TrifluoperazineA phenothiazine used to treat depression, anxiety, and agitation.
LoperamideA long acting antidiarrheal used to control nonspecific diarrhea and chronic diarrhea caused by inflammatory bowel disease, or gastroenteritis.
RanitidineA histamine H2 antagonist used to treat duodenal ulcers, Zollinger-Ellison syndrome, gastric ulcers, GERD, and erosive esophagitis.
GranisetronA 5HT3 antagonist used to treat nausea and vomiting in cancer therapy and postoperatively.
FamotidineA histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome.
MisoprostolA prostaglandin E1 analogue used to reduce the risk of NSAID-induced gastric ulcers.
MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
AlosetronA 5-HT3 antagonist used to treat diarrhea-predominant IBS.
DimenhydrinateA medication used to prevent and treat nausea, vomiting, vertigo, and motion sickness.
BalsalazideAn aminosalicylate used to treat ulcerative colitis.
DiphenhydramineA H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes.
TegaserodA serotonin-4 (5-HT4) receptor agonist indicated for the treatment of constipation predominant irritable bowel syndrome (IBS-C) specifically in women under the age of 65. There is currently no safety or efficacy data for use of tegaserol in men.
DiphenoxylateAn antidiarrheal medication used with atropine to manage diarrhea.
RabeprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
CyclizineAn antihistamine and antiemetic drug used for the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness, and vertigo.
DomperidoneA dopamine receptor antagonist used as a peristaltic stimulant and anti-emetic agent for dyspepsia, indigestion, epigastric pain, nausea, and vomiting.
RidogrelUsed as an adjunctive therapy to induce thrombolysis in patients suffering acute myocardial infarction.
RifaximinA rifamycin-based non-systemic antibiotic used for the treatment of gastrointestinal bacterial infections, such as traveler's diarrhea and irritable bowel syndrome, and reduction of overt hepatic encephalopathy recurrence in adults.
DiphenidolAn antiemetic agent used for the prevention and symptomatic treatment of nausea and vomiting associated with various conditions as Meniere's disease and surgery of the middle and inner ear.
MetoclopramideAn antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying.
DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
OlsalazineAn anti-inflammatory agent used in the treatment of inflammatory bowel disease and ulcerative colitis.
Bismuth subsalicylateAn antidiarrheal and anti-inflammatory agent used for symptomatic treatment of nausea, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract.
Magnesium oxideA compound commonly used as a laxative for the symptomatic relief of acid indigestion and upset stomach, and in health supplements for cardiovascular and neuromuscular health.
AlizaprideAlizapride is used in the treatment of nausea and vomiting, including postoperative nausea and vomiting.
KaolinA natural ingredient used for the short-term symptomatic treatment of various conditions including diarrhea, skin dryness, and minor skin bleeding.
Ursodeoxycholic acidA bile acid used for the treatment of primary biliary cirrhosis (PBC), dissolution of radiolucent gallstones in patients with a functioning gallbladder, and treatment of hepatobiliary disorders associated with cystic fibrosis in pediatric patients.
SorbitolA product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener.
SucrosofateNot Available
CarbenoxoloneAn agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise the drug is...
NaringeninNot Available
Deoxycholic acidA cytolytic agent injected subcutaneously to improve the appearance submental fat.
Taurocholic acidThe product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats...
DantronWithdrawn from the Canadian, US, and UK markets in 1998 due to genotoxicity.
OxyphenisatinA laxative that undergoes enterohepatic circulation. It may cause jaundice.
SofalconeInvestigated for use/treatment in gastroenteritis and ulcers.
EcabetFor the treatment of reflux oesophagitis and peptic ulcer disease.
DexlansoprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
AZD 3355Investigated for use/treatment in gastroesophageal reflux disease (GERD).
AlicaforsenInvestigated for use/treatment in crohn's disease and ulcerative colitis.
AlvimopanAn opioid antagonist used to reduce healing time of the upper and lower gastrointestinal tract following surgical procedures that involve bowel resection with primary anastomosis.
DexanabinolInvestigated for use/treatment in traumatic brain injuries and neurologic disorders.
CasopitantInvestigated for use/treatment in urinary incontinence and adverse effects (chemotherapy).
FosaprepitantAn antiemetic drug used in combination with other antiemetic agents for the prevention of acute and delayed nausea and vomiting caused by chemotherapy.
Aluminum hydroxideAn antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach.
Calcium carbonateAn ionic compound used as a calcium supplement or antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach.
Chenodeoxycholic acidA bile acid used for the treatment of primary biliary cirrhosis.
Cupric sulfateA compound used as an intravenous copper supplement for Total Parenteral Nutrition (TPN).
Ferulic acidNot Available
MetiamidePotential in the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion.
Roxatidine acetateFor the treatment of disorders of the upper gastro-intestinal region that are due to an excess of hydrochloric acid in the gastric juice, i.e. duodenal ulcers, benign gastric ulcers. Also...
Taurochenodeoxycholic acidTaurochenodeoxycholic acid is likely indicated as a choleretic and cholagogue. It is also being investigated for its role in inflammation and cancer therapy.
Tauroursodeoxycholic acidUsed in the treatment of cholesterol gallstones. Tauroursodeoxycholic acid is also being investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis,...
CholecystokininFor use as a diagnostic aid for evaluation of gallbladder disorders. It is also used in conjunction with secretin in pancreatic insufficiency .
TeduglutideA glucagon-like peptide-2 (GLP-2) analog used to treat patients with Short Bowel Syndrome (SBS) who require parenteral nutritional support.
MagaldrateAn antacid used to treat various conditions in the GI tract, such as esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux.
BromoprideBromopride in indicated in the treatment of nausea and vomiting, including PONV (post-operative nausea and vomiting), gastroesophageal reflux disease (GERD/GORD), as well as endoscopy preparation and radiographic studies of the...
BisacodylA stimulant laxative used for the temporary relief of occasional constipation and cleansing of the colon as a preparation for colonoscopy in adults.
VedolizumabAn integrin blocker and anti-inflammatory agent used to manage ulcerative colitis and Crohn's disease in adults with inadequate clinical response to immunomodulators.
TrimebutineA spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery.
Magnesium hydroxideAn inorganic compound used as a laxative and antacid.
PolaprezincPeptic ulcer disease, dyspepsia .
Picosulfuric acidA stimulant laxative used for cleansing of the colon as a preparation for colonoscopy in adults.
EluxadolineA mixed mu-opioid receptor agonist used to treat irritable bowel syndrome with diarrhea.
Magnesium trisilicateAn antacid used for the symptomatic treatment of peptic ulcers.
Polyethylene glycolA laxative used to treat constipation and used for bowel preparation before colonoscopies and other procedures.
RamosetronFor the treatment of nausea and vomiting and diarrhea-predominant irritable bowel syndrome in males.
PolycarbophilPolycarbophil is used to treat constipation and to help maintain regular bowel movements.
Sodium sulfateAn agent used for bowel cleansing prior to colonoscopy or barium enema X-ray examination.
Secretin porcineA secretin hormone used to stimulate pancreatic or gastric secretions to diagnose exocrine pancreas dysfunction, gastrinoma, and abnormalities in the bile and pancreatic ducts.
CarobAn extract from Carob used in allergy testing.
CarboxymethylcelluloseA compound used as an ophthalmic lubricant.
Plantago seedAn ingredient used in a variety of natural health products.
Magnesium citrateA laxative used in bowel preparation for colonoscopy or as a magnesium supplement.
Castor oilAn ingredient used in a variety of natural health products.
OpiumA medication used to treat moderate to severe pain.
SennosidesA laxative used to treat constipation.
PoloxaleneEthylene oxide/propylene oxide copolymer is used as a food additive. It belongs to the family of Epoxides. These are compounds containing a cyclic ether with three ring atoms (one oxygen...
Dehydrocholic acidNo approved therapeutic indications.
RebamipideRebamipide has been investigated for the treatment of Stomach Ulcer, Keratoconjunctivitis Sicca, and Gastric Adenoma and Early Gastric Cancer.
MosaprideMosapride is under investigation for the treatment and prevention of Postoperative Ileus and Gastric Peroral Endoscopic Pyloromyotomy (G-POEM). Mosapride has been investigated for the treatment and diagnostic of Constipation, Type...
RacecadotrilRacecadotril has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and Acute Gastroenteritis.
TropisetronFor the prevention of nausea and vomiting induced by cytotoxic therapy and postoperative.
AnisodamineAnisodamine has been investigated for the treatment of Intestinal Diseases.
BPC-157Bepecin is under investigation in clinical trial NCT02637284 (PCO-02 - Safety and Pharmacokinetics Trial).
LesogaberanLesogaberan has been used in trials studying the treatment and basic science of GERD, Reflux, Heartburn, Regurgitation, and Reflux Disease, among others.
GefarnateGefarnate has been investigated for the treatment and prevention of Stomach Ulcer, Duodenal Ulcer, and Cardio-cerebrovascular Disease.
VofopitantVofopitant has been used in trials studying the treatment of PTSD, Primary Insomnia, and Sleep Initiation and Maintenance Disorders.
LafutidineLafutidine has been investigated in Peptic Ulcer, Community-acquired Pneumonia, and Gastroesophageal Reflux Disease (GERD).
Pancreatic PolypeptidePancreatic Polypeptide has been investigated for the treatment of Diabetes Mellitus, Type 1.
LactitolAn orally administered osmotic laxative used to treat chronic idiopathic constipation.
IrsogladineIrsogladine is under investigation in clinical trial NCT02581696 (The Drug-drug Interaction and Safety of Lafutidine and Irsogladine Maleate in Healthy Adult Volunteers).
PepsinUsed as a pancreatic enzyme replacement in pancreatic insufficiency . It is intended to mimic naturally produced human pepsin . Pepsin powder is prepared from the gastric mucosa of pigs,...
Bismuth subnitrateA medication used as an antacid.
IpecacAn emetic agent used to induce vomiting in poisoning.
SulglicotideNot Annotated
HydrotalciteNot Annotated
EmetineNot Annotated
ProglumideNot Annotated
OtiloniumNot Annotated
CleboprideNot Annotated
MetopimazineNot Annotated
DexrabeprazoleNot Annotated
DixyrazineNot Annotated
EpomediolNot Annotated
EnprostilNot Annotated
Glutamic acidAn amino acid commonly found as a component in total parenteral nutrition.
PapainNo FDA-approved therapeutic indications.
BromelainsBromelain is a protease enzyme derived from the stems of pineapples that is composed of a mixture of different thiol endopeptidases and other components like phosphatase, glucosidase, peroxidase, cellulase, escharase,...
TilactaseA beta-D-galactosidase use to treat lactose intolerance.
Anethole trithioneA medication used to treat dry mouth associated with medication or radiotherapy of the head and neck.
Aluminium phosphateNot Available
Secretin humanA secretin hormone used to stimulate pancreatic or gastric secretions to diagnose exocrine pancreas dysfunction, gastrinoma, and abnormalities in the bile and pancreatic ducts.
Plantago ovata seedNot Annotated
Oxyphenisatin acetateNot Annotated
Calcium polycarbophilA bulk forming laxative used to treat constipation.
Glycocholic acidThe glycine conjugate of cholic acid. It acts as a detergent to solubilize fats for absorption and is itself absorbed.
EmodinEmodin has been investigated for the treatment of Polycystic Kidney.
EbselenEbselen has been investigated for the treatment and basic science of Meniere's Disease, Type 2 Diabetes Mellitus, and Type 1 Diabetes Mellitus.
Konjac mannanKonjac mannan is under investigation in clinical trial NCT01709955 (The Effects of Glucomannan on Weight Loss).
Gastric inhibitory polypeptideGastric inhibitory polypeptide is under investigation in clinical trial NCT03081676 (The Effect of GIP and GLP-1 on Insulin and Glucagon Secretion in Patients With HNF1A-diabetes Treated With or Without Sulphonylurea).
PalonosetronA serotonin antagonist used in the prophylaxis or management of vomiting that results from emetogenic chemotherapy, and for the management of postoperative nausea and vomiting.
ScopolamineAn anticholinergic used to treat excessive salivation, colicky abdominal pain, bradycardia, diverticulitis, IBS, and motion sickness.
PrucaloprideA P2Y12 platelet receptor antagonist used during percutaneous coronary intervention to reduce the risk for periprocedural myocardial infarction (MI), repeat coronary revascularization, and stent thrombosis (ST).
CatumaxomabFor use in the management of malignant ascites tumours via intraperitoneal infusion where standard therapy is not available or feasible [FDA Label].
CinitaprideIt is indicated to treat gastrointestinal disorders associated with motility disturbances like gastroesophageal reflux disease (GERD), non-ulcer dyspepsia and delayed gastric emptying.
LinaclotideA guanylate cyclase-C agonist used to treat constipation associated with irritable bowel syndrome or that is idiopathic in nature.
MaropitantMaropitant, used as maropitant citrate, is a neurokinin receptor antagonist, which was developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by...
EtrolizumabEtrolizumab has been used in trials studying the treatment of Crohn Disease and Ulcerative Colitis.
AcotiamideAcotiamide has been used in trials studying the treatment of Dyspepsia and Functional Dyspepsia.
PirnabinePirnabine has been used in trials studying the treatment of Chronic Idiopathic Constipation.
DolcanatideDolcanatide has been investigated in Exposure.
PlecanatideA laxative used to treat chronic idiopathic constipation and IBS with constipation.
Loperamide oxideNot Annotated
AlloinNot Annotated
Frangula purshiana barkNot Annotated
Pancrelipase lipaseA lipase used to treat pancreatic exocrine insufficiency.
Drugs & Drug Targets
DrugTargetType
Glycine betaineCholinesteraseenzyme
Glycine betaineProline dehydrogenase 1, mitochondrialenzyme
Glycine betaineApoptosis regulator Bcl-2target
Peppermint oilCytochrome P450 1A2enzyme
Peppermint oilCytochrome P450 3A4enzyme
PancrelipaseDietary fattarget
PancrelipaseDietary proteintarget
PancrelipaseDietary starchtarget
GlucagonGlucagon receptortarget
GlucagonGlucagon-like peptide 2 receptortarget
GlucagonGlucagon-like peptide 1 receptortarget
InfliximabTumor necrosis factortarget
OctreotideSomatostatin receptor type 1target
OctreotideSomatostatin receptor type 5target
OctreotideSomatostatin receptor type 2target
OctreotideMyeloperoxidaseenzyme
OctreotideCytochrome P450 3A4enzyme
CholineCholine-phosphate cytidylyltransferase Btarget
CholineAcetylcholinesterasetarget
CholineCholine-phosphate cytidylyltransferase Atarget
CholinePhospholipase D2target
CholineCholinesterasetarget
CholinePhospholipase D1target
CholinePhosphoethanolamine/phosphocholine phosphatasetarget
CholineSolute carrier family 22 member 2transporter
CholineSolute carrier family 22 member 1transporter
CholineSolute carrier family 22 member 3transporter
CholineSolute carrier family 22 member 5transporter
CholineSolute carrier family 22 member 4transporter
CholineCholine/ethanolaminephosphotransferase 1enzyme
CholineCholine transporter-like protein 1transporter
CholineCholine transporter-like protein 4transporter
CholineCholine transporter-like protein 2transporter
CholineCholine transporter-like protein 3transporter
CholineCholine/ethanolamine kinaseenzyme
CholineCholine O-acetyltransferaseenzyme
CholineCholine kinase alphaenzyme
CholineCholine dehydrogenase, mitochondrialenzyme
CholineHigh affinity choline transporter 1transporter
CholineNeuronal acetylcholine receptor subunit alpha-7target
LorazepamUDP-glucuronosyltransferase 2B15enzyme
LorazepamGABA(A) Receptortarget
LorazepamCytochrome P450 3A4enzyme
LorazepamGABA(A) Receptor Benzodiazepine Binding Sitetarget
Erythromycin23S ribosomal RNAtarget
ErythromycinCytochrome P450 3A4enzyme
ErythromycinCytochrome P450 3A7enzyme
ErythromycinP-glycoprotein 1transporter
ErythromycinSolute carrier organic anion transporter family member 1B1transporter
ErythromycinMotilin receptortarget
ErythromycinPotassium voltage-gated channel subfamily H member 2target
ErythromycinCytochrome P450 3A5enzyme
ErythromycinSolute carrier organic anion transporter family member 1B3transporter
ErythromycinBile salt export pumptransporter
ErythromycinCanalicular multispecific organic anion transporter 1transporter
ErythromycinSolute carrier organic anion transporter family member 1A2transporter
PantoprazolePotassium-transporting ATPase alpha chain 1target
PantoprazoleCytochrome P450 2C19enzyme
PantoprazoleCytochrome P450 3A4enzyme
PantoprazoleP-glycoprotein 1transporter
PantoprazoleATP-binding cassette sub-family G member 2transporter
PantoprazoleSolute carrier family 22 member 8transporter
PantoprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
BetazoleHistamine H2 receptortarget
OlanzapineDopamine D1 receptortarget
OlanzapineMuscarinic acetylcholine receptor M1target
OlanzapineMuscarinic acetylcholine receptor M3target
Olanzapine5-hydroxytryptamine receptor 2Atarget
OlanzapineDopamine D4 receptortarget
OlanzapineHistamine H1 receptortarget
OlanzapineMuscarinic acetylcholine receptor M4target
OlanzapineMuscarinic acetylcholine receptor M2target
OlanzapineDopamine D2 receptortarget
Olanzapine5-hydroxytryptamine receptor 2Ctarget
OlanzapineDopamine D3 receptortarget
OlanzapineAlpha-1B adrenergic receptortarget
OlanzapineCytochrome P450 1A2enzyme
Olanzapine5-hydroxytryptamine receptor 3Atarget
Olanzapine5-hydroxytryptamine receptor 6target
OlanzapineAlpha-1A adrenergic receptortarget
OlanzapineDopamine D5 receptortarget
OlanzapineSerum albumincarrier
OlanzapineAlpha-1-acid glycoprotein 1carrier
OlanzapineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
OlanzapineCytochrome P450 2D6enzyme
OlanzapineP-glycoprotein 1transporter
OlanzapineCytochrome P450 2C19enzyme
OlanzapineD(1) dopamine receptortarget
OlanzapineBeta adrenergic receptortarget
Olanzapine5-hydroxytryptamine receptor 1target
OlanzapineGABA(A) Receptor Benzodiazepine Binding Sitetarget
OlanzapineCytochrome P450 2C9enzyme
OlanzapineUDP-glucuronosyltransferase 1-4enzyme
OlanzapineCytochrome P450 3A4enzyme
OlanzapineCytochrome P450 3A Subfamilyenzyme
OmeprazolePotassium-transporting ATPase alpha chain 1target
OmeprazoleCytochrome P450 2C19enzyme
OmeprazoleCytochrome P450 3A4enzyme
OmeprazoleCytochrome P450 2C9enzyme
OmeprazoleCytochrome P450 1A2enzyme
OmeprazoleCanalicular multispecific organic anion transporter 2transporter
OmeprazoleP-glycoprotein 1transporter
OmeprazoleATP-binding cassette sub-family G member 2transporter
OmeprazoleCytochrome P450 1A1enzyme
OmeprazoleCytochrome P450 1B1enzyme
OmeprazoleCytochrome P450 2C18enzyme
OmeprazoleCytochrome P450 2C8enzyme
OmeprazoleCytochrome P450 2D6enzyme
OmeprazoleAryl hydrocarbon receptortarget
SucralfateFibrinogentarget
SucralfatePepsin A-5target
SucralfatePro-epidermal growth factortarget
SucralfateFibroblast growth factor 2target
DoxylamineHistamine H1 receptortarget
DoxylamineMuscarinic acetylcholine receptor M1target
DoxylamineCYP2B proteinenzyme
DoxylamineNuclear receptor subfamily 1 group I member 3target
ThiethylperazineDopamine D2 receptortarget
PromazineDopamine D2 receptortarget
Promazine5-hydroxytryptamine receptor 2Atarget
Promazine5-hydroxytryptamine receptor 2Ctarget
PromazineAlpha-1A adrenergic receptortarget
PromazineMuscarinic acetylcholine receptor M1target
PromazineHistamine H1 receptortarget
PromazineCytochrome P450 2C19enzyme
PromazineCytochrome P450 1A2enzyme
PromazineCytochrome P450 3A4enzyme
PromazineCytochrome P450 2C9enzyme
PromazineCytochrome P450 2D6enzyme
ProchlorperazineDopamine D2 receptortarget
ProchlorperazineCytochrome P450 2D6enzyme
ProchlorperazineHistamine H1 receptortarget
ProchlorperazineAlpha-1 adrenergic receptorstarget
ProchlorperazineAlpha-2 adrenergic receptorstarget
Cyproheptadine5-hydroxytryptamine receptor 2Atarget
CyproheptadineHistamine H1 receptortarget
CyproheptadineMuscarinic acetylcholine receptor M1target
CyproheptadineMuscarinic acetylcholine receptor M2target
CyproheptadineMuscarinic acetylcholine receptor M3target
Cyproheptadine5-hydroxytryptamine receptor 2Ctarget
CyproheptadineUDP-glucuronosyltransferase 1-3enzyme
Cyproheptadine5-hydroxytryptamine receptor 7target
LansoprazolePotassium-transporting ATPase alpha chain 1target
LansoprazoleCytochrome P450 2C19enzyme
LansoprazoleCytochrome P450 2C9enzyme
LansoprazoleCytochrome P450 3A4enzyme
LansoprazoleP-glycoprotein 1transporter
LansoprazoleATP-binding cassette sub-family G member 2transporter
LansoprazoleCytochrome P450 1A1enzyme
LansoprazoleCytochrome P450 1B1enzyme
LansoprazoleCytochrome P450 2C18enzyme
LansoprazoleCytochrome P450 2C8enzyme
LansoprazoleCytochrome P450 2D6enzyme
LansoprazoleMicrotubule-associated protein tautarget
LansoprazoleSolute carrier family 22 member 8transporter
LansoprazoleSolute carrier family 22 member 1transporter
LansoprazoleSolute carrier family 22 member 2transporter
LansoprazoleSolute carrier family 22 member 3transporter
DroperidolDopamine D2 receptortarget
DroperidolAlpha-1A adrenergic receptortarget
ChlorpromazineDopamine D2 receptortarget
Chlorpromazine5-hydroxytryptamine receptor 2Atarget
ChlorpromazineCytochrome P450 2D6enzyme
ChlorpromazineCholinesteraseenzyme
ChlorpromazineCytochrome P450 1A2enzyme
ChlorpromazineSerum albumincarrier
ChlorpromazineP-glycoprotein 1transporter
ChlorpromazineDopamine D1 receptortarget
Chlorpromazine5-hydroxytryptamine receptor 1Atarget
ChlorpromazineAlpha-1A adrenergic receptortarget
ChlorpromazineAlpha-1B adrenergic receptortarget
ChlorpromazineCytochrome P450 2E1enzyme
ChlorpromazineCytochrome P450 3A4enzyme
ChlorpromazineHistamine H1 receptortarget
ChlorpromazinePotassium voltage-gated channel subfamily H member 2target
ChlorpromazineD(1) dopamine receptortarget
ChlorpromazineDopamine D3 receptortarget
ChlorpromazineDopamine D4 receptortarget
ChlorpromazineDopamine D5 receptortarget
Chlorpromazine5-hydroxytryptamine receptor 2Ctarget
Chlorpromazine5-hydroxytryptamine 2 receptortarget
ChlorpromazineAlpha-1 adrenergic receptorstarget
ChlorpromazineAlpha-2 adrenergic receptorstarget
ChlorpromazineMuscarinic acetylcholine receptor M1target
ChlorpromazineMuscarinic acetylcholine receptor M3target
ChlorpromazineSphingomyelin phosphodiesterasetarget
ChlorpromazineCalmodulintarget
Chlorpromazinealpha1-acid glycoproteintarget
Chlorpromazine5-hydroxytryptamine receptor 6target
Chlorpromazine5-hydroxytryptamine receptor 7target
ChlorpromazineHistamine H4 receptortarget
ChlorpromazineBile salt export pumptransporter
NabiloneCannabinoid receptor 2target
NabiloneCannabinoid receptor 1target
NabiloneCytochrome P450 2E1enzyme
NabiloneCytochrome P450 2C8enzyme
NabiloneCytochrome P450 2C9enzyme
CimetidineHistamine H2 receptortarget
CimetidineCytochrome P450 1A2enzyme
CimetidineCytochrome P450 2D6enzyme
CimetidineCytochrome P450 2C19enzyme
CimetidineCytochrome P450 3A4enzyme
CimetidineCytochrome P450 3A5enzyme
CimetidineP-glycoprotein 1transporter
CimetidineSolute carrier family 22 member 2transporter
CimetidineSolute carrier family 22 member 1transporter
CimetidineSolute carrier family 22 member 3transporter
CimetidineSolute carrier family 22 member 5transporter
CimetidineSolute carrier family 22 member 6transporter
CimetidineSolute carrier family 22 member 8transporter
CimetidineMultidrug and toxin extrusion protein 1transporter
CimetidineSolute carrier family 22 member 4transporter
CimetidineSolute carrier family 22 member 11transporter
CimetidineSolute carrier family 22 member 7transporter
CimetidineCytochrome P450 11B1, mitochondrialenzyme
CimetidineCytochrome P450 2C8enzyme
CimetidineCytochrome P450 2C9enzyme
CimetidineCytochrome P450 2E1enzyme
CimetidineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
CimetidineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
CimetidineBile salt export pumptransporter
CimetidineMultidrug and toxin extrusion protein 2transporter
HaloperidolDopamine D2 receptortarget
HaloperidolGlutamate receptor ionotropic, NMDA 2Btarget
HaloperidolDopamine D1 receptortarget
HaloperidolCytochrome P450 1A2enzyme
HaloperidolCytochrome P450 2D6enzyme
Haloperidol5-hydroxytryptamine receptor 2Atarget
HaloperidolDopamine D3 receptortarget
HaloperidolCytochrome P450 3A4enzyme
HaloperidolCytochrome P450 3A5enzyme
HaloperidolCytochrome P450 3A7enzyme
HaloperidolP-glycoprotein 1transporter
HaloperidolCarbonyl reductase [NADPH] 1enzyme
HaloperidolUDP-glucuronosyltransferase 1-9enzyme
HaloperidolCytochrome P450 2C19enzyme
HaloperidolCytochrome P450 2C9enzyme
HaloperidolMelanin-concentrating hormone receptor 1target
HaloperidolSynaptic vesicular amine transportertarget
Haloperidol5-hydroxytryptamine receptor 2Ctarget
HaloperidolSigma non-opioid intracellular receptor 1target
HaloperidolHistamine H1 receptortarget
HaloperidolMuscarinic acetylcholine receptor M3target
HaloperidolAlpha-1A adrenergic receptortarget
HaloperidolAlpha-2A adrenergic receptortarget
HaloperidolAlpha-2B adrenergic receptortarget
HaloperidolAlpha-2C adrenergic receptortarget
Haloperidol5-hydroxytryptamine receptor 1Atarget
Haloperidol5-hydroxytryptamine receptor 6target
Haloperidol5-hydroxytryptamine receptor 7target
HaloperidolCytochrome P450 1A1enzyme
TriflupromazineDopamine D1 receptortarget
TriflupromazineDopamine D2 receptortarget
TriflupromazineMuscarinic acetylcholine receptor M1target
TriflupromazineMuscarinic acetylcholine receptor M2target
Triflupromazine5-hydroxytryptamine receptor 2Btarget
TriflupromazineP-glycoprotein 1transporter
TriflupromazineCholinesteraseenzyme
LactuloseEvolved beta-galactosidase subunit alphatarget
NizatidineHistamine H2 receptortarget
NizatidineP-glycoprotein 1transporter
NizatidineCholinesteraseenzyme
Cisapride5-hydroxytryptamine receptor 4target
Cisapride5-hydroxytryptamine receptor 3Atarget
CisapridePotassium voltage-gated channel subfamily H member 2target
Cisapride5-hydroxytryptamine receptor 2Atarget
CisaprideCytochrome P450 3A4enzyme
CisaprideCytochrome P450 3A5enzyme
CisaprideCytochrome P450 3A7enzyme
CisaprideCytochrome P450 2A6enzyme
CisaprideCytochrome P450 2B6enzyme
CisaprideCytochrome P450 2C19enzyme
CisaprideCytochrome P450 2C8enzyme
CisaprideCytochrome P450 2C9enzyme
CisaprideCytochrome P450 2D6enzyme
PirenzepineMuscarinic acetylcholine receptor M1target
AprepitantNeurokinin 1 receptortarget
AprepitantCytochrome P450 3A4enzyme
AprepitantCytochrome P450 2C9enzyme
AprepitantCytochrome P450 2C19enzyme
ApomorphineDopamine D2 receptortarget
ApomorphineDopamine D1 receptortarget
ApomorphineDopamine D4 receptortarget
ApomorphineDopamine D3 receptortarget
ApomorphineDopamine D5 receptortarget
ApomorphineNeuron-specific vesicular protein calcyontarget
ApomorphineAlpha-2C adrenergic receptortarget
ApomorphineAlpha-2B adrenergic receptortarget
Apomorphine5-hydroxytryptamine receptor 2Ctarget
Apomorphine5-hydroxytryptamine receptor 1Atarget
Apomorphine5-hydroxytryptamine receptor 2Atarget
Apomorphine5-hydroxytryptamine receptor 2Btarget
ApomorphineAlpha-2A adrenergic receptortarget
Apomorphine5-hydroxytryptamine receptor 1Dtarget
Apomorphine5-hydroxytryptamine receptor 1Btarget
EsomeprazolePotassium-transporting ATPase alpha chain 1target
EsomeprazoleCytochrome P450 2C19enzyme
EsomeprazoleCytochrome P450 3A4enzyme
EsomeprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
EsomeprazoleP-glycoprotein 1transporter
EsomeprazoleSolute carrier family 22 member 8transporter
MeclizineHistamine H1 receptortarget
MeclizineNuclear receptor subfamily 1 group I member 3target
MeclizineCytochrome P450 2D6enzyme
MeclizineSerum albumincarrier
Dolasetron5-hydroxytryptamine receptor 3Atarget
DolasetronCytochrome P450 3A4enzyme
DolasetronCytochrome P450 2D6enzyme
DolasetronCytochrome P450 2C9enzyme
PropanthelineMuscarinic acetylcholine receptor M1target
SulfasalazineAcetyl-CoA acetyltransferase, mitochondrialtarget
SulfasalazineCystine/glutamate transportertarget
SulfasalazineATP-binding cassette sub-family G member 2transporter
SulfasalazineCanalicular multispecific organic anion transporter 1transporter
SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit betatarget
SulfasalazineProstaglandin G/H synthase 2target
SulfasalazinePeroxisome proliferator-activated receptor gammatarget
SulfasalazineProstaglandin G/H synthase 1target
SulfasalazineArachidonate 5-lipoxygenasetarget
SulfasalazineProton-coupled folate transportertransporter
SulfasalazineThromboxane-A synthasetarget
SulfasalazinePhospholipase A2target
SulfasalazineSolute carrier organic anion transporter family member 1B1transporter
SulfasalazineSolute carrier organic anion transporter family member 1B3transporter
SulfasalazineSolute carrier organic anion transporter family member 2B1transporter
TrifluoperazineDopamine D2 receptortarget
TrifluoperazineAlpha-1A adrenergic receptortarget
TrifluoperazineNeuron-specific vesicular protein calcyontarget
TrifluoperazineXanthine dehydrogenase/oxidaseenzyme
TrifluoperazineUDP-glucuronosyltransferase 1-4enzyme
TrifluoperazineCytochrome P450 1A2enzyme
TrifluoperazineP-glycoprotein 1transporter
TrifluoperazineCalmodulintarget
TrifluoperazineTroponin C, slow skeletal and cardiac musclestarget
TrifluoperazineProtein S100-A4target
LoperamideVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
LoperamideMu-type opioid receptortarget
LoperamideCalmodulintarget
LoperamidePro-opiomelanocortintarget
LoperamideDelta-type opioid receptortarget
LoperamideCytochrome P450 3A4enzyme
LoperamideP-glycoprotein 1transporter
LoperamideKappa-type opioid receptortarget
LoperamideCytochrome P450 2C8enzyme
LoperamideCytochrome P450 2B6enzyme
LoperamideCytochrome P450 2D6enzyme
LoperamideNuclear receptor subfamily 1 group I member 3target
RanitidineHistamine H2 receptortarget
RanitidineCytochrome P450 1A2enzyme
RanitidineCytochrome P450 2D6enzyme
RanitidineSolute carrier family 22 member 1transporter
RanitidineP-glycoprotein 1transporter
RanitidineSolute carrier family 22 member 8transporter
RanitidineCytochrome P450 3A4enzyme
RanitidineAcetylcholinesterasetarget
RanitidineSolute carrier family 22 member 2transporter
RanitidineAcetylcholinesteraseenzyme
Granisetron5-hydroxytryptamine receptor 3Atarget
GranisetronCytochrome P450 3A4enzyme
GranisetronCytochrome P450 1A1enzyme
FamotidineHistamine H2 receptortarget
FamotidineSolute carrier family 22 member 2transporter
FamotidineSolute carrier family 22 member 8transporter
FamotidineMultidrug and toxin extrusion protein 1transporter
FamotidineCytochrome P450 1A2enzyme
FamotidineSolute carrier family 22 member 6transporter
MisoprostolProstaglandin E2 receptor EP2 subtypetarget
MisoprostolProstaglandin E2 receptor EP3 subtypetarget
MisoprostolProstaglandin E2 receptor EP4 subtypetarget
MisoprostolProstaglandin E2 receptor EP1 subtypetarget
MethylprednisoloneGlucocorticoid receptortarget
MethylprednisoloneCytochrome P450 3A4enzyme
MethylprednisoloneP-glycoprotein 1transporter
MethylprednisoloneCytochrome P450 3A Subfamilyenzyme
MethylprednisoloneCytochrome P450 2A6enzyme
MethylprednisoloneCytochrome P450 1B1enzyme
MethylprednisoloneCytochrome P450 2B6enzyme
MethylprednisoloneCytochrome P450 2C8enzyme
MethylprednisoloneCytochrome P450 2C9enzyme
MethylprednisoloneCytochrome P450 2C19enzyme
MethylprednisoloneAnnexin A1target
Methylprednisolone20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)enzyme
Methylprednisolone11beta-hydroxysteroid dehydrogenaseenzyme
MethylprednisoloneSerum albumincarrier
Alosetron5-hydroxytryptamine receptor 3Atarget
AlosetronCytochrome P450 1A2enzyme
AlosetronCytochrome P450 2C9enzyme
AlosetronCytochrome P450 3A4enzyme
AlosetronCytochrome P450 2E1enzyme
DimenhydrinateHistamine H1 receptortarget
BalsalazideProstaglandin G/H synthase 1target
BalsalazideProstaglandin G/H synthase 2target
BalsalazideArachidonate 5-lipoxygenasetarget
BalsalazidePeroxisome proliferator-activated receptor gammatarget
BalsalazideNADPH azoreductaseenzyme
DiphenhydramineHistamine H1 receptortarget
DiphenhydramineCytochrome P450 2D6enzyme
DiphenhydramineCytochrome P450 2C9enzyme
DiphenhydramineCytochrome P450 2C19enzyme
DiphenhydramineSolute carrier family 22 member 2transporter
DiphenhydramineSolute carrier family 22 member 5transporter
DiphenhydramineProstaglandin G/H synthase 1enzyme
DiphenhydramineMuscarinic acetylcholine receptor M2target
Tegaserod5-hydroxytryptamine receptor 4target
Tegaserod5-hydroxytryptamine receptor 2Btarget
Tegaserod5-hydroxytryptamine receptor 2Ctarget
Tegaserod5-hydroxytryptamine receptor 2Atarget
TegaserodSodium-dependent serotonin transportertransporter
TegaserodCytochrome P450 1A2enzyme
TegaserodCytochrome P450 2C8enzyme
TegaserodCytochrome P450 2D6enzyme
TegaserodCytochrome P450 2E1enzyme
TegaserodATP-binding cassette sub-family G member 2transporter
TegaserodP-glycoprotein 1transporter
DiphenoxylateMu-type opioid receptortarget
DiphenoxylateDelta-type opioid receptortarget
RabeprazolePotassium-transporting ATPase alpha chain 1target
RabeprazoleCytochrome P450 3A4enzyme
RabeprazoleCytochrome P450 2C19enzyme
RabeprazoleATP-binding cassette sub-family G member 2transporter
RabeprazoleCytochrome P450 1A1enzyme
RabeprazoleCytochrome P450 1A2enzyme
RabeprazoleCytochrome P450 2C9enzyme
RabeprazoleCytochrome P450 2D6enzyme
RabeprazoleCytochrome P450 2C8enzyme
CyclizineHistamine H1 receptortarget
CyclizineEstrogen sulfotransferasetarget
CyclizineCytochrome P450 2C9enzyme
DomperidoneDopamine D2 receptortarget
DomperidoneCytochrome P450 3A4enzyme
DomperidoneCytochrome P450 3A5enzyme
DomperidoneCytochrome P450 3A7enzyme
DomperidoneP-glycoprotein 1transporter
DomperidoneCytochrome P450 1A2enzyme
DomperidoneCytochrome P450 2B6enzyme
DomperidoneCytochrome P450 2C8enzyme
DomperidoneCytochrome P450 2D6enzyme
DomperidoneDopamine D3 receptortarget
RidogrelThromboxane-A synthasetarget
RidogrelThromboxane A2 receptortarget
RifaximinDNA-directed RNA polymerase subunit betatarget
RifaximinNuclear receptor subfamily 1 group I member 2target
RifaximinCytochrome P450 3A4enzyme
RifaximinCytochrome P450 2C19enzyme
RifaximinCytochrome P450 2C8enzyme
DiphenidolMuscarinic acetylcholine receptor M2target
DiphenidolMuscarinic acetylcholine receptor M1target
DiphenidolMuscarinic acetylcholine receptor M3target
MetoclopramideMuscarinic acetylcholine receptor M1target
MetoclopramideDopamine D2 receptortarget
MetoclopramideCytochrome P450 2D6enzyme
Metoclopramide5-hydroxytryptamine receptor 4target
Metoclopramide5-hydroxytryptamine receptor 3Atarget
MetoclopramideCytochrome P450 3A4enzyme
MetoclopramideCytochrome P450 1A2enzyme
MetoclopramideP-glycoprotein 1transporter
MetoclopramideAlpha-1-acid glycoprotein 1carrier
DexamethasoneGlucocorticoid receptortarget
DexamethasoneAnnexin A1target
DexamethasoneNitric oxide synthase, inducibletarget
DexamethasoneNuclear receptor subfamily 0 group B member 1target
DexamethasoneCytochrome P450 3A4enzyme
DexamethasoneCytochrome P450 3A5enzyme
DexamethasoneCytochrome P450 3A7enzyme
DexamethasoneBile salt export pumptransporter
DexamethasoneP-glycoprotein 1transporter
DexamethasoneCanalicular multispecific organic anion transporter 1transporter
DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DexamethasoneATP-binding cassette sub-family G member 2transporter
DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DexamethasoneCytochrome P450 1A1enzyme
DexamethasoneCytochrome P450 2A6enzyme
DexamethasoneCytochrome P450 2B6enzyme
DexamethasoneCytochrome P450 2C19enzyme
DexamethasoneCytochrome P450 2C8enzyme
DexamethasoneCytochrome P450 2E1enzyme
DexamethasoneCytochrome P450 3A43enzyme
DexamethasoneCytochrome P450 4A11enzyme
DexamethasoneNuclear receptor subfamily 1 group I member 2target
DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DexamethasoneSerum albumincarrier
DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DexamethasoneSolute carrier family 22 member 8transporter
OlsalazineInterferon gammatarget
OlsalazineThiopurine S-methyltransferasetarget
Bismuth subsalicylateSerum albumincarrier
Bismuth subsalicylateSerotransferrincarrier
AlizaprideDopamine D2 receptortarget
Ursodeoxycholic acidAldo-keto reductase family 1 member C2target
Ursodeoxycholic acidBile salt export pumptransporter
Ursodeoxycholic acidSolute carrier organic anion transporter family member 1A2transporter
Ursodeoxycholic acidCanalicular multispecific organic anion transporter 1transporter
Ursodeoxycholic acidMultidrug resistance-associated protein 4transporter
Ursodeoxycholic acidIleal sodium/bile acid cotransportertransporter
Ursodeoxycholic acidSodium/bile acid cotransportertransporter
Ursodeoxycholic acidCytochrome P450 2E1enzyme
Ursodeoxycholic acidBile acid receptortarget
SucrosofateFibroblast growth factor 1target
SucrosofateFibroblast growth factor receptor 2target
Carbenoxolone3-alpha-(or 20-beta)-hydroxysteroid dehydrogenasetarget
CarbenoxoloneCorticosteroid 11-beta-dehydrogenase isozyme 1target
NaringeninSolute carrier organic anion transporter family member 2B1transporter
NaringeninP-glycoprotein 1transporter
NaringeninMultidrug resistance-associated protein 1transporter
NaringeninATP-binding cassette sub-family G member 2transporter
NaringeninHTH-type transcriptional regulator TtgRtarget
NaringeninEstrogen receptor alphatarget
NaringeninAldo-keto reductase family 1 member C1target
NaringeninCytochrome P450 1B1target
NaringeninKAT8 regulatory NSL complex subunit 3target
NaringeninSex hormone-binding globulintarget
NaringeninCytochrome P450 19A1target
NaringeninEstrogen receptor betatarget
Deoxycholic acidBile salt export pumptransporter
Deoxycholic acidSolute carrier organic anion transporter family member 1A2transporter
Deoxycholic acidIleal sodium/bile acid cotransportertransporter
Deoxycholic acidSodium/bile acid cotransportertransporter
Deoxycholic acidSteroid Delta-isomerasetarget
Deoxycholic acidPpcAtarget
Deoxycholic acidElongation factor Tu GTP-binding domain-containing protein 1target
Deoxycholic acidCholoylglycine hydrolasetarget
Deoxycholic acidLactaldehyde dehydrogenasetarget
Deoxycholic acidAcriflavine resistance protein Btarget
Deoxycholic acidCytochrome c oxidase subunit 1target
Deoxycholic acidCytochrome c oxidase subunit 2target
Deoxycholic acidBile acid receptortarget
Deoxycholic acidGlutathione S-transferase Ptarget
Deoxycholic acidG-protein coupled bile acid receptor 1target
Taurocholic acidBile salt-activated lipasetarget
Taurocholic acidGastrotropintarget
Taurocholic acidBile salt export pumptransporter
Taurocholic acidMultidrug resistance-associated protein 1transporter
Taurocholic acidSolute carrier organic anion transporter family member 1A2transporter
Taurocholic acidIleal sodium/bile acid cotransportertransporter
Taurocholic acidCanalicular multispecific organic anion transporter 1transporter
Taurocholic acidSolute carrier organic anion transporter family member 1B1transporter
Taurocholic acidCanalicular multispecific organic anion transporter 2transporter
Taurocholic acidMultidrug resistance-associated protein 4transporter
Taurocholic acidP-glycoprotein 1transporter
Taurocholic acidSolute carrier family 22 member 6transporter
Taurocholic acidMultidrug resistance-associated protein 7transporter
Taurocholic acidSolute carrier family 22 member 8transporter
Taurocholic acidSolute carrier organic anion transporter family member 4A1transporter
Taurocholic acidATP-binding cassette sub-family C member 11transporter
Taurocholic acidSolute carrier organic anion transporter family member 1C1transporter
Taurocholic acidSolute carrier organic anion transporter family member 3A1transporter
Taurocholic acidATP-binding cassette sub-family G member 2transporter
Taurocholic acidSolute carrier organic anion transporter family member 2B1transporter
Taurocholic acidMonocarboxylate transporter 1transporter
Taurocholic acidSodium/bile acid cotransportertransporter
Taurocholic acidOrganic solute transporter subunit alphatransporter
Taurocholic acidOrganic solute transporter subunit betatransporter
Taurocholic acidSolute carrier organic anion transporter family member 1B3transporter
Taurocholic acidCystine/glutamate transportertransporter
Taurocholic acidBile acid receptortarget
DantronSerum albumincarrier
SofalconeCarbonyl reductase [NADPH] 1enzyme
EcabetNADPH oxidase organizer 1target
EcabetUrease subunit alphatarget
DexlansoprazolePotassium-transporting ATPase alpha chain 1target
DexlansoprazoleCytochrome P450 2C19enzyme
DexlansoprazoleCytochrome P450 3A4enzyme
DexlansoprazolePotassium-transporting ATPase subunit betatarget
DexlansoprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
AZD 3355Cellular tumor antigen p53target
AlvimopanMu-type opioid receptortarget
AlvimopanKappa-type opioid receptortarget
AlvimopanDelta-type opioid receptortarget
DexanabinolTumor necrosis factortarget
CasopitantCytochrome P450 3A4target
CasopitantNeurokinin 1 receptortarget
FosaprepitantCytochrome P450 3A4enzyme
FosaprepitantCytochrome P450 2C9enzyme
Chenodeoxycholic acidBile acid receptortarget
Chenodeoxycholic acidSterol 26-hydroxylase, mitochondrialenzyme
Chenodeoxycholic acidCytochrome P450 3A4enzyme
Chenodeoxycholic acidUDP-glucuronosyltransferase 2B7enzyme
Chenodeoxycholic acidNuclear receptor subfamily 1 group I member 2target
Chenodeoxycholic acidG-protein coupled bile acid receptor 1target
Chenodeoxycholic acidAldo-keto reductase family 1 member C2target
Cupric sulfateSerum albumintransporter
Cupric sulfateCeruloplasmintransporter
Cupric sulfatePhenylalanine-4-hydroxylaseenzyme
Cupric sulfateProtein-lysine 6-oxidaseenzyme
Cupric sulfateCytochrome c oxidase subunit 1enzyme
Ferulic acidEndo-1,4-beta-xylanase Ytarget
Ferulic acidEndo-1,4-beta-xylanase Ztarget
Ferulic acidEst1etarget
Ferulic acidO-methyltransferasetarget
MetiamideHistamine H2 receptortarget
Roxatidine acetateHistamine H2 receptortarget
Taurochenodeoxycholic acidSolute carrier organic anion transporter family member 1A2transporter
Taurochenodeoxycholic acidCystine/glutamate transportertransporter
Taurochenodeoxycholic acidCytochrome P450 3A4enzyme
Tauroursodeoxycholic acidSolute carrier organic anion transporter family member 1A2transporter
Tauroursodeoxycholic acidCystine/glutamate transportertransporter
Tauroursodeoxycholic acidCytochrome P450 3A1enzyme
Tauroursodeoxycholic acidCytochrome P450 3A2enzyme
Tauroursodeoxycholic acidCytochrome P450 2A1enzyme
Tauroursodeoxycholic acidCytochrome P450 2A2enzyme
Tauroursodeoxycholic acidCytochrome P450 2B1enzyme
Tauroursodeoxycholic acidCytochrome P450 2B2enzyme
Tauroursodeoxycholic acidCytochrome P450 2B9enzyme
CholecystokininSolute carrier organic anion transporter family member 1B3transporter
CholecystokininCholecystokinin receptor type Atarget
CholecystokininRAF proto-oncogene serine/threonine-protein kinasetarget
CholecystokininMitogen-activated protein kinase 3target
CholecystokininPro-epidermal growth factortarget
CholecystokininProtein kinase C beta typetarget
CholecystokininGastrin/cholecystokinin type B receptortarget
CholecystokininSolute carrier organic anion transporter family member 1B1transporter
CholecystokininSolute carrier organic anion transporter family member 2B1transporter
TeduglutideGlucagon-like peptide 2 receptortarget
BromoprideDopamine D2 receptortarget
VedolizumabIntegrin alpha-4target
VedolizumabIntegrin beta-7target
TrimebutineMu-type opioid receptortarget
TrimebutineVoltage-dependent L-type calcium channeltarget
TrimebutineCalcium-activated potassium channeltarget
TrimebutineVoltage-dependent T-type calcium channeltarget
TrimebutineMuscarinic acetylcholine receptor M1target
TrimebutineMuscarinic acetylcholine receptor M2target
TrimebutineMuscarinic acetylcholine receptor M3target
TrimebutineMuscarinic acetylcholine receptor M4target
TrimebutineCytochrome P450 3A4enzyme
PolaprezincTumor necrosis factortarget
PolaprezincInterleukin-6target
PolaprezincInterleukin-3target
PolaprezincSuperoxide dismutase [Cu-Zn]enzyme
PolaprezincHeme oxygenase 1enzyme
PolaprezincSuperoxide dismutase [Mn], mitochondrialenzyme
PolaprezincGlutathione S-transferase theta-1enzyme
PolaprezincGlutathione peroxidase 1enzyme
PolaprezincPeroxiredoxin-1enzyme
PolaprezincPeroxiredoxin-5, mitochondrialenzyme
PolaprezincVascular endothelial growth factor receptor 1target
PolaprezincBeta-nerve growth factortarget
PolaprezincPlatelet-derived growth factor receptor betatarget
PolaprezincHeat shock protein HSP 90-alphatarget
PolaprezincHeat shock protein HSP 90-betatarget
Picosulfuric acidArylsulfate sulfotransferaseenzyme
EluxadolineMu-type opioid receptortarget
EluxadolineDelta-type opioid receptortarget
EluxadolineKappa-type opioid receptortarget
EluxadolineSolute carrier organic anion transporter family member 1B1transporter
EluxadolineCanalicular multispecific organic anion transporter 1transporter
EluxadolineSolute carrier family 22 member 8transporter
Polyethylene glycolP-glycoprotein 1transporter
Ramosetron5-hydroxytryptamine receptor 3Atarget
RamosetronCytochrome P450 1A2enzyme
Sodium sulfateCarbonic anhydrase 2target
Sodium sulfateCarbonic anhydrase 1target
CarboxymethylcelluloseSolute carrier family 2, facilitated glucose transporter member 1target
Castor oilProstaglandin E2 receptor EP3 subtypetarget
Castor oilProstaglandin E2 receptor EP4 subtypetarget
OpiumDelta-type opioid receptortarget
OpiumKappa-type opioid receptortarget
OpiumMu-type opioid receptortarget
OpiumSerum albumincarrier
OpiumBeta-2-microglobulincarrier
OpiumCytochrome P450 2D6enzyme
OpiumCytochrome P450 3A4enzyme
SennosidesReverse transcriptase/RNaseHtarget
SennosidesAquaporin-3target
Tropisetron5-hydroxytryptamine receptor 3Atarget
AnisodamineCytochrome P450 2D6enzyme
VofopitantNeurokinin 1 receptortarget
IpecacCytochrome P450 2D6enzyme
IpecacCytochrome P450 3A4enzyme
OtiloniumCytochrome P450 3A4enzyme
DexrabeprazoleCytochrome P450 2C19enzyme
Glutamic acidGlutamate dehydrogenase 1, mitochondrialtarget
Glutamic acidGlutamate receptor ionotropic, kainate 1target
Glutamic acidGlutamate receptor 1target
Glutamic acidGlutamate--cysteine ligase regulatory subunittarget
Glutamic acidGlutamate carboxypeptidase 2target
Glutamic acidGlutamate decarboxylase 2target
Glutamic acidGlutamate decarboxylase 1target
Glutamic acidFormimidoyltransferase-cyclodeaminasetarget
Glutamic acidGlutamate receptor 2target
Glutamic acidGlutamate receptor 3target
Glutamic acidGlutamate receptor 4target
Glutamic acidDelta-1-pyrroline-5-carboxylate synthasetarget
Glutamic acidGlutamate receptor ionotropic, kainate 2target
Glutamic acidGlutamate receptor ionotropic, kainate 3target
Glutamic acidMetabotropic glutamate receptor 1target
Glutamic acidMetabotropic glutamate receptor 4target
Glutamic acidGlutamate receptor ionotropic, kainate 4target
Glutamic acidGlutamate receptor ionotropic, kainate 5target
Glutamic acidMetabotropic glutamate receptor 7target
Glutamic acidMetabotropic glutamate receptor 8target
Glutamic acidExcitatory amino acid transporter 5target
Glutamic acid5-oxoprolinasetarget
Glutamic acidPhosphoribosylformylglycinamidine synthasetarget
Glutamic acidBranched-chain-amino-acid aminotransferase, mitochondrialtarget
Glutamic acidGlutamate receptor ionotropic, NMDA 2Dtarget
Glutamic acidGlutamate receptor ionotropic, delta-2target
Glutamic acidGlutamate receptor ionotropic, NMDA 3Btarget
Glutamic acidGlutaminase kidney isoform, mitochondrialtarget
Glutamic acidAspartate aminotransferase, mitochondrialtarget
Glutamic acidBifunctional glutamate/proline--tRNA ligasetarget
Glutamic acidAsparagine synthetase [glutamine-hydrolyzing]target
Glutamic acidGlutamine synthetasetarget
Glutamic acidAspartate aminotransferase, cytoplasmictarget
Glutamic acidTyrosine aminotransferasetarget
Glutamic acidAlanine aminotransferase 1target
Glutamic acidVitamin K-dependent gamma-carboxylasetarget
Glutamic acidExcitatory amino acid transporter 1target
Glutamic acidExcitatory amino acid transporter 2target
Glutamic acidExcitatory amino acid transporter 3target
Glutamic acidGlutamate--cysteine ligase catalytic subunittarget
Glutamic acidExcitatory amino acid transporter 4target
Glutamic acidGlutamate dehydrogenase 2, mitochondrialtarget
Glutamic acidGMP synthase [glutamine-hydrolyzing]target
Glutamic acidBranched-chain-amino-acid aminotransferase, cytosolictarget
Glutamic acid4-aminobutyrate aminotransferase, mitochondrialtarget
Glutamic acidGlutamate receptor ionotropic, NMDA 1target
Glutamic acidFolylpolyglutamate synthase, mitochondrialtarget
Glutamic acidGlutamyl aminopeptidasetarget
Glutamic acidGlutamate receptor ionotropic, NMDA 2Atarget
Glutamic acidGlutamate receptor ionotropic, NMDA 2Btarget
Glutamic acidGlutamate receptor ionotropic, NMDA 2Ctarget
Glutamic acidAspartate aminotransferasetarget
Glutamic acidProbable glutamate--tRNA ligase, mitochondrialtarget
Glutamic acidGlutamine-dependent NAD(+) synthetasetarget
Glutamic acidN-acetylglutamate synthase, mitochondrialtarget
Glutamic acidKynurenine/alpha-aminoadipate aminotransferase, mitochondrialtarget
Glutamic acidGlutamate receptor ionotropic, NMDA 3Atarget
Glutamic acidAlanine aminotransferase 2target
Glutamic acidMitochondrial glutamate carrier 2target
Glutamic acidMitochondrial glutamate carrier 1target
Glutamic acidAlpha-aminoadipic semialdehyde synthase, mitochondrialtarget
Glutamic acidGlutaminase liver isoform, mitochondrialtarget
Glutamic acidAspartyl aminopeptidasetarget
Glutamic acidCystine/glutamate transportertarget
Glutamic acidCarboxypeptidase Qtarget
Glutamic acidPhosphoserine aminotransferasetarget
Glutamic acidMonocarboxylate transporter 10transporter
Glutamic acidMonocarboxylate transporter 1transporter
PapainToll-like receptor 4target
TilactaseLactosetarget
Aluminium phosphateSerotransferrintarget
Aluminium phosphateSodium/potassium-transporting ATPase subunit alpha-1target
Aluminium phosphateSerum albumincarrier
Aluminium phosphateKallikrein-1target
Aluminium phosphateAmyloid beta A4 proteintarget
Secretin humanSecretin receptortarget
Glycocholic acidGastrotropintarget
Glycocholic acidSolute carrier organic anion transporter family member 1A2transporter
Glycocholic acidSolute carrier organic anion transporter family member 1B1transporter
Glycocholic acidSolute carrier organic anion transporter family member 1B3transporter
EmodinCasein kinase II subunit alphatarget
EmodinPutative ketoacyl reductasetarget
Emodin3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZtarget
EmodinAryl hydrocarbon receptortarget
EbselenBifunctional epoxide hydrolase 2target
Palonosetron5-hydroxytryptamine receptor 3Atarget
PalonosetronCytochrome P450 2D6enzyme
PalonosetronCytochrome P450 3A4enzyme
PalonosetronCytochrome P450 1A2enzyme
ScopolamineMuscarinic acetylcholine receptor M1target
ScopolamineSucrase-isomaltase, intestinaltarget
ScopolamineMuscarinic acetylcholine receptor M2target
ScopolamineMuscarinic acetylcholine receptor M3target
ScopolamineMuscarinic acetylcholine receptor M4target
ScopolamineMuscarinic acetylcholine receptor M5target
ScopolamineP-glycoprotein 1transporter
ScopolamineNeuronal acetylcholine receptor subunit alpha-4target
ScopolamineNeuronal acetylcholine receptor subunit beta-2target
Prucalopride5-hydroxytryptamine receptor 4target
PrucaloprideCytochrome P450 3A4enzyme
PrucaloprideSerum albumincarrier
PrucaloprideP-glycoprotein 1transporter
CatumaxomabEpithelial cell adhesion moleculetarget
CatumaxomabLow affinity immunoglobulin gamma Fc region receptor II-atarget
CatumaxomabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
CatumaxomabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
CatumaxomabT-cell surface glycoprotein CD3 epsilon chaintarget
CatumaxomabHigh affinity immunoglobulin gamma Fc receptor Itarget
Cinitapride5-hydroxytryptamine receptor 1Atarget
Cinitapride5-hydroxytryptamine receptor 4target
Cinitapride5-hydroxytryptamine receptor 2Atarget
LinaclotideHeat-stable enterotoxin receptortarget
PlecanatideGuanylate cyclase soluble subunit alpha-2target
Pancrelipase lipaseDietary fattarget