Displaying drugs 1151 - 1175 of 2780 in total
Name | Weight | Structure | Description | Categories |
---|---|---|---|---|
Bedaquiline | 555.505 C32H31BrN2O2 | A diarylquinoline antimycobacterial used in combination with other antibacterials to treat pulmonary multidrug resistant tuberculosis (MDR-TB). | Diarylquinoline Antimycobacterial | |
Ponatinib | 532.5595 C29H27F3N6O | A kinase inhibitor used to treat patients with various types of chronic myeloid leukemia (CML). | Bcr-Abl Tyrosine Kinase Inhibitors / Protein Kinase Inhibitors | |
Enzalutamide | 464.436 C21H16F4N4O2S | A second-generation androgen receptor inhibitor used to treat castration-resistant prostate cancer and metastatic castration-sensitive prostate cancer. | Antiandrogens | |
Aclidinium | 484.651 C26H30NO4S2 | An inhaled long-acting anticholinergic used as a maintenance bronchodilator in patients with chronic obstructive pulmonary disease (COPD). | Agents producing tachycardia | |
Regorafenib | 482.815 C21H15ClF4N4O3 | A kinase inhibitor used to treat patients with metastatic colorectal cancer, unresectable, locally advanced, or metastatic gastrointestinal stromal tumors, and hepatocellular carcinoma. | Protein Kinase Inhibitors | |
Tofacitinib | 312.3696 C16H20N6O | A Janus kinase (JAK) inhibitor used to treat rheumatic conditions, such as rheumatoid arthritis and ankylosing spondylitis, and ulcerative colitis. | Selective Immunosuppressants | |
Mirabegron | 396.506 C21H24N4O2S | A beta-3 adrenergic agonist used to treat overactive bladder and neurogenic detrusor overactivity. | Drugs for Urinary Frequency and Incontinence | |
Linaclotide | 1526.736 C59H79N15O21S6 | A guanylate cyclase-C agonist used to treat different types of constipation, such as irritable bowel syndrome-related constipation, idiopathic constipation, and functional constipation. | Guanylate Cyclase-C Agonist / Guanylyl Cyclase C Agonists | |
Carfilzomib | 719.9099 C40H57N5O7 | A proteasome inhibitor used either alone or in conjunction with a chemotherapy regimen to treat patients with relapsed or refractory multiple myeloma. | Proteasome Inhibitors | |
Icosapent ethyl | 330.5042 C22H34O2 | An ethyl ester of eicosapentaenoic acid (EPA) that reduces synthesis and enhances clearance of triglycerides that is used to treat patients with severe hypertriglyceridemia. | Antiplatelet agents / Hypolipidemic Agents / Lipid Regulating Agents | |
Gadoxetic acid | 681.75 C23H30GdN3O11 | A gadolinium-based contrast agent (GBCA) used with contrasted magnetic resonance imaging (MRI) to detect and visualize the liver. | Paramagnetic Contrast Media | |
Perampanel | 349.393 C23H15N3O | A non-competitive AMPA glutamate receptor antagonist used to treat partial-onset seizures with or without secondarily generalized seizures, and as adjunctive treatment of primary generalized tonic-clonic seizures in patients with epilepsy. | Noncompetitive AMPA Glutamate Receptor Antagonist / Receptors, AMPA, antagonists & inhibitors | |
Linagliptin | 472.5422 C25H28N8O2 | A dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus. | DPP-IV Inhibitors / Incretins / Purines / Quinazolines | |
Vemurafenib | 489.922 C23H18ClF2N3O3S | A kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation. | B-Raf serine-threonine kinase (BRAF) inhibitors / Protein Kinase Inhibitors / Sulfonamides | |
Teriflunomide | 270.2073 C12H9F3N2O2 | A pyrimidine synthesis inhibitor with anti-inflammatory and immunomodulatory properties used to treat patients with the relapsing-remitting form of multiple sclerosis. | Dihydroorotate dehydrogenase (DHODH) inhibitors / Selective Immunosuppressants | |
Ruxolitinib | 306.365 C17H18N6 | A kinase inhibitor used to treat various types of myelofibrosis, polycythemia vera in patients who have not responded to or cannot tolerate hydroxyurea, and to treat graft-versus-host disease in cases that are refractory to steroid treatment. | Agents for Dermatitis, Excluding Corticosteroids / Protein Kinase Inhibitors | |
Cabozantinib | 501.514 C28H24FN3O5 | A tyrosine kinase inhibitor used to treat advanced renal cell carcinoma, hepatocellular carcinoma, and medullary thyroid cancer. | Protein Kinase Inhibitors | |
Fidaxomicin | 1058.05 C52H74Cl2O18 | A macrolide antibiotic used to treat diarrhea associated with Clostridium difficile infection. | Anti-Bacterial Agents | |
Boceprevir | 519.6767 C27H45N5O5 | A hepatitis C virus NS3/4A protease inhibitor used in combination with other medications to treat chronic hepatitis C genotype 1 infection. Boceprevir is not indicated as monotherapy. | Antivirals for treatment of HCV infections / Protease Inhibitors | |
Gabapentin enacarbil | 329.393 C16H27NO6 | A gabapentin prodrug used to treat Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN). | Anti-epileptic Agent | |
Eribulin | 729.908 C40H59NO11 | A microtubule inhibitor used to treat metastatic breast cancer and metastatic or unresectable liposarcoma. | Microtubule Inhibitors | |
Fingolimod | 307.4708 C19H33NO2 | A sphingosine 1-phosphate receptor modulator used to treat patients with the relapsing-remitting form of multiple sclerosis (MS) and studied to manage lung complications of COVID-19. | Selective Immunosuppressants | |
Ulipristal | 433.592 C28H35NO3 | A selective progesterone receptor modulator used for emergency contraception after unprotected intercourse or in a situation where a planned method of contraception has failed. | Contraceptives, Postcoital / Progesterone Receptor Modulators | |
Crizotinib | 450.337 C21H22Cl2FN5O | A receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive. | Anaplastic lymphoma kinase (ALK) inhibitors / Protein Kinase Inhibitors | |
Rilpivirine | 366.4185 C22H18N6 | A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1). | Non-Nucleoside Reverse Transcriptase Inhibitors |
Displaying drugs 1151 - 1175 of 2780 in total