Sulfonamides

A group of compounds that contain the structure SO2NH2.
DrugDrug NameDrug Indication
DB00263SulfisoxazoleFor the treatment of severe, repeated, or long-lasting urinary tract infections, meningococcal meningitis, acute otitis media, trachoma, inclusion conjunctivitis, nocardiosis, chancroid, toxoplasmosis, malaria and other bacterial infections.
DB00576SulfamethizoleFor the treatment of urinary tract infection
DB05245Silver sulfadiazineIndicated as an adjunct for the prevention and treatment of wound sepsis in patients with second- and third-degree burns.
DB06729SulfaphenazoleFor the treatment bacterial infections.
DB06795MafenideMafenide is indicated in the treatment of severe burns.
DB00259SulfanilamideFor the treatment of vulvovaginitis caused by Candida albicans.
DB06147SulfathiazoleSulfathiazole is effective against a wide range of gram positive and gram negative pathogenic microorganisms. Although no longer used in humans, it is used in cattle.
DB00310ChlorthalidoneFor management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension.
DB00436BendroflumethiazideFor the treatment of high blood pressure and management of edema related to heart failure.
DB00524MetolazoneFor the treatment of hypertension, alone or in combination with other antihypertensive drugs of a different class.
DB00562BenzthiazideFor the treatment of high blood pressure and management of edema.
DB00669SumatriptanFor the treatment of migraine attacks with or without aura.
DB00774HydroflumethiazideUsed as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. Also used in the management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension.
DB00795SulfasalazineFor the treatment of Crohn's disease and rheumatoid arthritis as a second-line agent.
DB01032ProbenecidFor the reduction of serum uric acid concentrations in chronic gouty arthritis and tophaceous gout in patients with frequent disabling gout attacks. Has also been effectively used to promote uric acid excretion in hyperuricemia secondary to the administration of thiazide and related diuretics.
DB01119DiazoxideUsed parentally to treat hypertensive emergencies. Also used to treat hypoglycemia secondary to insulinoma.
DB01264DarunavirDarunavir, co-administered with ritonavir, and with other antiretroviral agents, is indicated for the treatment of human immunodeficiency virus (HIV) infection in antiretroviral treatment-experienced adult patients, such as those with HIV-1 strains resistant to more than one protease inhibitor.
DB01298SulfacytineUsed orally in the treatment of acute urinary tract infections.
DB01299SulfadoxineSulfadoxine is used in combination with pyrimethamine for the treatment or prevention of malaria. It can also be used to treat various infections in livestock as well. Sulfadoxine and pyrimethamine is indicated for the treatment of Plasmodium falciparum malaria in those patients in whom chloroquine resistance is suspected.
DB01324PolythiazidePolythiazide is a thiazide diuretic used to decrease edema and decrease blood pressure.
DB01582SulfamethazineFor the treatment bacterial infections causing bronchitis, prostatitis and urinary tract infections.
DB06290SimeprevirIndicated for the treatment of adults with chronic hepatitis C virus (HCV) infection: typically in combination with sofosbuvir in patients with HCV genotype 1 without cirrhosis or with compensated cirrhosis and in combination with peginterferon alfa (Peg-IFN-alfa) and ribavirin (RBV) in patients with HCV genotype 1 or 4 without cirrhosis or with compensated cirrhosis. Resistance: Reduced susceptibility to simeprevir was most commonly associated with the viral NS3 Q80K polymorphism. Amino acid substitutions at NS3 positions S122, R155 and/or D168 are also shown to reduce susceptibility to simeprevir in genotype 1a/b patients.
DB08796PipazethateFor the treatment of cough.
DB01015SulfamethoxazoleFor the treatment bacterial infections causing bronchitis, prostatitis and urinary tract infections.
DB01144DiclofenamideFor adjunctive treatment of: chronic simple (open-angle) glaucoma, secondary glaucoma, and preoperatively in acute angle-closure glaucoma where delay of surgery is desired in order to lower intraocular pressure
DB00664SulfametopyrazineFor the treatment of urinary tract infection and chronic bronchitis.
DB00203SildenafilFor the treatment of erectile dysfunction and to relieve symptoms of pulmonary arterial hypertension (PAH).
DB00232MethyclothiazideFor use in the management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension. Also used as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy.
DB00311EthoxzolamideFor use in the treatment of duodenal ulcers, as a diuretic, and in the treatment of glaucoma, and may also be useful in the treatment of seizures associated with epilepsy.
DB00359SulfadiazineFor the treatment of rheumatic fever and meningococcal meningitis
DB00482CelecoxibFor relief and management of osteoarthritis (OA), rheumatoid arthritis (RA), juvenile rheumatoid arthritis (JRA), ankylosing spondylitis, acute pain, primary dysmenorrhea and oral adjunct to usual care for patients with familial adenomatous polyposis
DB00606CyclothiazideCyclothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of hypertension.
DB00634SulfacetamideFor the treatment of bacterial vaginitis, keratitis, acute conjunctivitis, and blepharitis.
DB00695FurosemideFor the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and renal disease, including the nephrotic syndrome. Also for the treatment of hypertension alone or in combination with other antihypertensive agents.
DB00808IndapamideFor the treatment of hypertension, alone or in combination with other antihypertensive drugs, as well as for the treatment of salt and fluid retention associated with congestive heart failure or edema from pregnancy (appropriate only in the management of edema of pathologic origin during pregnancy when clearly needed). Also used for the management of edema as a result of various causes.
DB00880ChlorothiazideChlorothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of hypertension.
DB00887BumetanideFor the treatment of edema associated with congestive heart failure, hepatic and renal disease including the nephrotic syndrome.
DB00891SulfapyridineFor the treatment of dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum
DB00999HydrochlorothiazideFor the treatment of high blood pressure and management of edema.
DB01021TrichlormethiazideUsed in the treatment of oedema (including that associated with heart failure) and hypertension.
DB01098RosuvastatinUsed as an adjunct to dietary therapy to treat primary hyperlipidemia (heterozygous familial and nonfamilial), mixed dyslipidemia and hypertriglyceridemia. Also indicated for homozygous familial hypercholesterolemia as an adjunct to other lipid-lowering therapies or when other such therapies are not available. Furthermore, it is used to slow the progression of atherosclerosis and for primary prevention of cardiovascular disease.
DB01581SulfamerazineA sulfanilamide that is used as an antibacterial agent. It can be used to treat bronchitis, prostatitis and urinary tract infections.
DB04707HydroxyfasudilNot Available
DB06150SulfadimethoxineFor use in the treatment of infections.
DB079965-(2-methylpiperazine-1-sulfonyl)isoquinolineNot Available
DB08798SulfamoxoleFor the treatment of bacterial infection.
DB08961AzosemideNot Available
DB12051SetrobuvirNot Available
DB12921ChlorsulfaquinoxalineNot Available
DB13532CyclopenthiazideNot Available
DB13792ClopamideNot Available
DrugDrug NameTargetType
DB00263SulfisoxazoleDihydropteroate synthasetarget
DB00263SulfisoxazoleCytochrome P450 2C9enzyme
DB00263SulfisoxazoleCytochrome P450 3A4enzyme
DB00576SulfamethizoleDihydropteroate synthasetarget
DB00576SulfamethizoleSerum albumincarrier
DB00576SulfamethizoleCytochrome P450 2C9enzyme
DB05245Silver sulfadiazineDNAtarget
DB06729SulfaphenazoleCytochrome P450 2C9enzyme
DB06729SulfaphenazoleCytochrome P450 2A6enzyme
DB06729SulfaphenazoleCytochrome P450 2B6enzyme
DB06729SulfaphenazoleCytochrome P450 2C8enzyme
DB06729SulfaphenazoleCytochrome P450 2D6enzyme
DB06729SulfaphenazoleDihydropteroate synthasetarget
DB06795MafenideCarbonic anhydrase 6target
DB00259SulfanilamideDihydropteroate synthasetarget
DB00259SulfanilamideCytochrome P450 2C19enzyme
DB00259SulfanilamideCytochrome P450 2C9enzyme
DB00259SulfanilamideCytochrome P450 2D6enzyme
DB00259SulfanilamideCytochrome P450 2E1enzyme
DB00259SulfanilamideCytochrome P450 3A4enzyme
DB06147SulfathiazoleDihydropteroate synthetasetarget
DB06147SulfathiazoleCytochrome P450 19A1enzyme
DB00310ChlorthalidoneSolute carrier family 12 member 1target
DB00436BendroflumethiazideSolute carrier family 12 member 3target
DB00436BendroflumethiazideCarbonic anhydrase 1target
DB00436BendroflumethiazideCarbonic anhydrase 2target
DB00436BendroflumethiazideCarbonic anhydrase 4target
DB00436BendroflumethiazideCalcium-activated potassium channel subunit alpha-1target
DB00436BendroflumethiazideThiopurine S-methyltransferaseenzyme
DB00524MetolazoneSolute carrier family 12 member 3target
DB00562BenzthiazideSolute carrier family 12 member 3target
DB00562BenzthiazideCarbonic anhydrase 1target
DB00562BenzthiazideCarbonic anhydrase 2target
DB00562BenzthiazideCarbonic anhydrase 4target
DB00562BenzthiazideCarbonic anhydrase 9target
DB00562BenzthiazideCarbonic anhydrase 12target
DB00669Sumatriptan5-hydroxytryptamine receptor 1Dtarget
DB00669Sumatriptan5-hydroxytryptamine receptor 1Btarget
DB00669Sumatriptan5-hydroxytryptamine receptor 1Ftarget
DB00669SumatriptanAmine oxidase [flavin-containing] Aenzyme
DB00669Sumatriptan5-hydroxytryptamine receptor 1Atarget
DB00669SumatriptanSolute carrier organic anion transporter family member 1A2transporter
DB00669SumatriptanMultidrug resistance protein 1transporter
DB00669SumatriptanATP-binding cassette sub-family G member 2transporter
DB00669SumatriptanSolute carrier organic anion transporter family member 1B1transporter
DB00774HydroflumethiazideSolute carrier family 12 member 1target
DB00774HydroflumethiazideSodium/potassium-transporting ATPase subunit alpha-1target
DB00774HydroflumethiazideCarbonic anhydrase 4target
DB00774HydroflumethiazideCalcium-activated potassium channel subunit alpha-1target
DB00774HydroflumethiazideCarbonic anhydrase 2target
DB00774HydroflumethiazideCarbonic anhydrase 1target
DB00774HydroflumethiazideCarbonic anhydrase 9target
DB00774HydroflumethiazideCarbonic anhydrase 12target
DB00795SulfasalazineAcetyl-CoA acetyltransferase, mitochondrialtarget
DB00795SulfasalazineCystine/glutamate transportertarget
DB00795SulfasalazineATP-binding cassette sub-family G member 2transporter
DB00795SulfasalazineCanalicular multispecific organic anion transporter 1transporter
DB00795SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
DB00795SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00795SulfasalazineProstaglandin G/H synthase 2target
DB00795SulfasalazinePeroxisome proliferator-activated receptor gammatarget
DB00795SulfasalazineProstaglandin G/H synthase 1target
DB00795SulfasalazineArachidonate 5-lipoxygenasetarget
DB00795SulfasalazineCytochrome P450 3A5enzyme
DB00795SulfasalazineProton-coupled folate transportertransporter
DB00795SulfasalazineThromboxane-A synthasetarget
DB00795SulfasalazinePhospholipase A2target
DB01032ProbenecidSolute carrier family 22 member 8target
DB01032ProbenecidSolute carrier family 22 member 11target
DB01032ProbenecidSerum albumincarrier
DB01032ProbenecidCytochrome P450 2C9enzyme
DB01032ProbenecidCytochrome P450 2C19enzyme
DB01032ProbenecidSolute carrier family 22 member 2transporter
DB01032ProbenecidSolute carrier family 22 member 1transporter
DB01032ProbenecidCanalicular multispecific organic anion transporter 2transporter
DB01032ProbenecidMultidrug resistance-associated protein 4transporter
DB01032ProbenecidMultidrug resistance-associated protein 5transporter
DB01032ProbenecidMonocarboxylate transporter 2transporter
DB01032ProbenecidSolute carrier family 22 member 5transporter
DB01032ProbenecidMultidrug resistance-associated protein 6transporter
DB01032ProbenecidMultidrug resistance protein 1transporter
DB01032ProbenecidMultidrug resistance-associated protein 1transporter
DB01032ProbenecidSolute carrier organic anion transporter family member 1A2transporter
DB01032ProbenecidMonocarboxylate transporter 1transporter
DB01032ProbenecidSodium/bile acid cotransportertransporter
DB01032ProbenecidSolute carrier family 22 member 6transporter
DB01032ProbenecidSolute carrier family 22 member 10transporter
DB01032ProbenecidSolute carrier family 22 member 8transporter
DB01032ProbenecidCanalicular multispecific organic anion transporter 1transporter
DB01032ProbenecidATP-binding cassette sub-family C member 11transporter
DB01032ProbenecidSolute carrier family 22 member 11transporter
DB01032ProbenecidSolute carrier organic anion transporter family member 1C1transporter
DB01032ProbenecidSolute carrier family 22 member 7transporter
DB01032ProbenecidSolute carrier family 22 member 6target
DB01032ProbenecidPannexin-1target
DB01032ProbenecidCytochrome P450 2C8enzyme
DB01032ProbenecidCytochrome P450 3A4enzyme
DB01032ProbenecidSolute carrier family 22 member 12transporter
DB01032ProbenecidSolute carrier family 2, facilitated glucose transporter member 9transporter
DB01032ProbenecidTaste receptor type 2 member 16target
DB01119DiazoxideSolute carrier family 12 member 3target
DB01119DiazoxideCarbonic anhydrase 1target
DB01119DiazoxideCarbonic anhydrase 2target
DB01119DiazoxideCalcium-activated potassium channel subunit alpha-1target
DB01119DiazoxideSodium/potassium-transporting ATPase subunit alpha-1target
DB01119DiazoxideATP-sensitive inward rectifier potassium channel 11target
DB01119DiazoxideGlutamine synthetaseenzyme
DB01264DarunavirHuman immunodeficiency virus type 1 proteasetarget
DB01264DarunavirCytochrome P450 3A4enzyme
DB01298SulfacytineDihydropteroate synthasetarget
DB01299SulfadoxineDihydropteroate synthetasetarget
DB01299SulfadoxineBifunctional dihydrofolate reductase-thymidylate synthasetarget
DB01324PolythiazideSolute carrier family 12 member 3target
DB01582SulfamethazineDihydropteroate synthasetarget
DB01582SulfamethazineSerum albumincarrier
DB01582SulfamethazineArylamine N-acetyltransferaseenzyme
DB06290SimeprevirNS3 proteasetarget
DB06290SimeprevirSerum albumincarrier
DB06290SimeprevirCytochrome P450 1A2enzyme
DB06290SimeprevirMultidrug resistance protein 1transporter
DB06290SimeprevirSolute carrier organic anion transporter family member 1B1transporter
DB06290SimeprevirSolute carrier organic anion transporter family member 1B3transporter
DB06290SimeprevirCYP3Aenzyme
DB06290SimeprevirCytochrome P450 3A4enzyme
DB06290SimeprevirCanalicular multispecific organic anion transporter 1transporter
DB06290SimeprevirATP-binding cassette sub-family G member 2transporter
DB06290SimeprevirSolute carrier organic anion transporter family member 2B1transporter
DB06290SimeprevirSodium/bile acid cotransportertransporter
DB06290SimeprevirBile salt export pumptransporter
DB01015SulfamethoxazoleBifunctional protein FolCtarget
DB01015SulfamethoxazoleCytochrome P450 2C9enzyme
DB01015SulfamethoxazoleSerum albumincarrier
DB01015SulfamethoxazoleArylamine N-acetyltransferase 1enzyme
DB01015SulfamethoxazoleArylamine N-acetyltransferase 2enzyme
DB01015SulfamethoxazoleProstaglandin G/H synthase 1enzyme
DB01015SulfamethoxazoleUDP-glucuronosyltransferase 1-9enzyme
DB01015SulfamethoxazoleDihydropteroate synthasetarget
DB01015SulfamethoxazoleCytochrome P450 2C8enzyme
DB01015SulfamethoxazoleCytochrome P450 3A4enzyme
DB01015SulfamethoxazoleGlutathione S-transferase Ptarget
DB01144DiclofenamideCarbonic anhydrase 1target
DB01144DiclofenamideCytochrome P450 2C9enzyme
DB01144DiclofenamideCarbonic anhydrase 4target
DB01144DiclofenamideCarbonic anhydrase 2target
DB01144DiclofenamideCarbonic anhydrase 7target
DB01144DiclofenamideCarbonic anhydrase 3target
DB00664SulfametopyrazineDihydropteroate synthetasetarget
DB00203SildenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00203SildenafilCytochrome P450 2C9enzyme
DB00203SildenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00203SildenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00203SildenafilCytochrome P450 3A4enzyme
DB00203SildenafilCytochrome P450 3A5enzyme
DB00203SildenafilCytochrome P450 3A7enzyme
DB00203SildenafilMultidrug resistance-associated protein 4transporter
DB00203SildenafilMultidrug resistance-associated protein 5transporter
DB00203SildenafilMultidrug resistance-associated protein 7transporter
DB00203SildenafilCytochrome P450 2C19enzyme
DB00203SildenafilCytochrome P450 2D6enzyme
DB00203SildenafilCytochrome P450 1A1enzyme
DB00203SildenafilCytochrome P450 2E1enzyme
DB00232MethyclothiazideSolute carrier family 12 member 1target
DB00232MethyclothiazideCarbonic anhydrase 4target
DB00232MethyclothiazideCarbonic anhydrase 2target
DB00232MethyclothiazideCarbonic anhydrase 1target
DB00311EthoxzolamideCarbonic anhydrase 1target
DB00311EthoxzolamideSolute carrier family 22 member 6transporter
DB00311EthoxzolamideCarbonic anhydrase 2target
DB00311EthoxzolamideCarbonic anhydrase 4target
DB00311EthoxzolamideCarbonic anhydrase 7target
DB00311EthoxzolamideCarbonic anhydrase 3target
DB00359SulfadiazineCytochrome P450 2C9enzyme
DB00359SulfadiazineDihydropteroate synthetasetarget
DB00359SulfadiazineCytochrome P450 2C8enzyme
DB00359SulfadiazineCytochrome P450 2E1enzyme
DB00359SulfadiazineCytochrome P450 3A4enzyme
DB00482CelecoxibProstaglandin G/H synthase 2target
DB00482Celecoxib3-phosphoinositide-dependent protein kinase 1target
DB00482CelecoxibCytochrome P450 2C9enzyme
DB00482CelecoxibCytochrome P450 2D6enzyme
DB00482CelecoxibMultidrug resistance-associated protein 4transporter
DB00482CelecoxibCytochrome P450 3A4enzyme
DB00482CelecoxibSerum albumincarrier
DB00482CelecoxibAlpha-1-acid glycoprotein 1carrier
DB00482CelecoxibCytochrome P450 2C8enzyme
DB00482CelecoxibCarbonic anhydrase 2target
DB00482CelecoxibCarbonic anhydrase 3target
DB00606CyclothiazideSodium/potassium-transporting ATPase subunit gammatarget
DB00606CyclothiazideCarbonic anhydrase 1target
DB00606CyclothiazideCarbonic anhydrase 2target
DB00606CyclothiazideCarbonic anhydrase 4target
DB00606CyclothiazideSolute carrier family 22 member 6transporter
DB00606CyclothiazideSecreted frizzled-related protein 4target
DB00634SulfacetamideDihydropteroate synthasetarget
DB00634SulfacetamideDihydropteroate synthase type-1target
DB00634SulfacetamideFolic acid synthesis protein FOL1target
DB00695FurosemideSolute carrier family 12 member 1target
DB00695FurosemideSerum albumincarrier
DB00695FurosemideSolute carrier family 22 member 6transporter
DB00695FurosemideSolute carrier family 22 member 5transporter
DB00695FurosemideSolute carrier family 22 member 8transporter
DB00695FurosemideCanalicular multispecific organic anion transporter 1transporter
DB00695FurosemideSolute carrier organic anion transporter family member 2A1transporter
DB00695FurosemideSolute carrier family 22 member 11transporter
DB00695Furosemide6-phosphogluconate dehydrogenase, decarboxylatingenzyme
DB00695FurosemideCarbonic anhydrase 2target
DB00808IndapamidePotassium voltage-gated channel subfamily KQT member 1target
DB00808IndapamidePotassium voltage-gated channel subfamily E member 1target
DB00808IndapamideCytochrome P450 3A4enzyme
DB00880ChlorothiazideSolute carrier family 12 member 3target
DB00880ChlorothiazideCarbonic anhydrase 1target
DB00880ChlorothiazideCarbonic anhydrase 2target
DB00880ChlorothiazideCarbonic anhydrase 4target
DB00880ChlorothiazideSolute carrier family 22 member 6transporter
DB00887BumetanideSolute carrier family 12 member 1target
DB00887BumetanideCystic fibrosis transmembrane conductance regulatortarget
DB00887BumetanideSolute carrier family 12 member 2target
DB00887BumetanideSolute carrier family 12 member 4target
DB00887BumetanideSolute carrier family 12 member 5target
DB00887BumetanideSodium/bile acid cotransportertransporter
DB00887BumetanideSolute carrier family 22 member 6transporter
DB00887BumetanideSolute carrier family 22 member 8transporter
DB00887BumetanideSolute carrier family 22 member 11transporter
DB00887BumetanideSolute carrier family 22 member 7transporter
DB00887BumetanideSolute carrier organic anion transporter family member 1A2transporter
DB00887BumetanideProstaglandin G/H synthase 2enzyme
DB00891SulfapyridineDihydropteroate synthase type-1target
DB00891SulfapyridineCytochrome P450 2C9enzyme
DB00999HydrochlorothiazideSolute carrier family 12 member 3target
DB00999HydrochlorothiazideCarbonic anhydrase 1target
DB00999HydrochlorothiazideCarbonic anhydrase 2target
DB00999HydrochlorothiazideCarbonic anhydrase 4target
DB00999HydrochlorothiazideCarbonic anhydrase 9target
DB00999HydrochlorothiazideCarbonic anhydrase 12target
DB00999HydrochlorothiazideSolute carrier family 22 member 6transporter
DB00999HydrochlorothiazideCalcium-activated potassium channel subunit alpha-1target
DB01021TrichlormethiazideSolute carrier family 12 member 1target
DB01021TrichlormethiazideSodium/potassium-transporting ATPase subunit alpha-1target
DB01021TrichlormethiazideCarbonic anhydrase 4target
DB01021TrichlormethiazideCarbonic anhydrase 2target
DB01021TrichlormethiazideCarbonic anhydrase 1target
DB01021TrichlormethiazideThiopurine S-methyltransferaseenzyme
DB01098Rosuvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB01098RosuvastatinCytochrome P450 2C9enzyme
DB01098RosuvastatinMultidrug resistance-associated protein 4transporter
DB01098RosuvastatinMultidrug resistance-associated protein 1transporter
DB01098RosuvastatinCytochrome P450 2C19enzyme
DB01098RosuvastatinCytochrome P450 3A4enzyme
DB01098RosuvastatinCytochrome P450 3A5enzyme
DB01098RosuvastatinSolute carrier organic anion transporter family member 1A2transporter
DB01098RosuvastatinSolute carrier organic anion transporter family member 1B3transporter
DB01098RosuvastatinSolute carrier organic anion transporter family member 2B1transporter
DB01098RosuvastatinCystine/glutamate transportertransporter
DB01098RosuvastatinSolute carrier organic anion transporter family member 1B1transporter
DB01098RosuvastatinBile salt export pumptransporter
DB01098RosuvastatinATP-binding cassette sub-family G member 2transporter
DB01098RosuvastatinSerum albumincarrier
DB01098RosuvastatinCanalicular multispecific organic anion transporter 1transporter
DB01581SulfamerazineDihydropteroate synthasetarget
DB01581SulfamerazineSerum albumincarrier
DB04707HydroxyfasudilRho-associated protein kinase 1target
DB04707HydroxyfasudilcAMP-dependent protein kinase catalytic subunit alphatarget
DB04707HydroxyfasudilcAMP-dependent protein kinase inhibitor alphatarget
DB06150SulfadimethoxineCytochrome P450 2C9enzyme
DB079965-(2-methylpiperazine-1-sulfonyl)isoquinolinecAMP-dependent protein kinase catalytic subunit alphatarget
DB079965-(2-methylpiperazine-1-sulfonyl)isoquinolinecAMP-dependent protein kinase inhibitor alphatarget
DB08798SulfamoxoleDihydropteroate synthetasetarget
DB08798SulfamoxoleCytochrome P450 2C9enzyme