Sulfonamides

A group of compounds that contain the structure SO2NH2.
DrugDrug NameDrug Description
DB00263SulfisoxazoleA sulfonamide antibiotic used with other antibiotics to prevent and treat a variety of bacterial infections.
DB00576SulfamethizoleA sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections.
DB05245Silver sulfadiazineA topical sulfonamide antibiotic that acts on the bacterial cell wall and cell membrane; approved for the treatment of burns.
DB06729SulfaphenazoleFor the treatment bacterial infections.
DB06795MafenideAn antimicrobial topical agent indicated for use as an adjunctive treatment to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds.
DB06147SulfathiazoleSulfathiazole is effective against a wide range of gram positive and gram negative pathogenic microorganisms. Although no longer used in humans, it is used in cattle.
DB13248PhthalylsulfathiazolePhthalylsulfathiazole is a broad spectrum antibiotic which is part of the drug class, sulfonamides. It was used as an antibiotic for bowel surgery, and for infections of the colon .
DB13580SuccinylsulfathiazoleNot Annotated
DB13726SulfaguanidineNot Annotated
DB00310ChlorthalidoneA diuretic used to treat hypertension or edema caused by heart failure, renal failure, hepatic cirrhosis, estrogen therapy, and other conditions.
DB00436BendroflumethiazideA diuretic used to suppress lactation and to treat hypertension and edema.
DB00524MetolazoneA thiazide-like diuretic used to treat hypertension.
DB00562BenzthiazideFor the treatment of high blood pressure and management of edema.
DB00669SumatriptanA serotonin receptor agonist used to treat migraines and cluster headaches.
DB00774HydroflumethiazideA thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure and liver cirrhosis.
DB00795SulfasalazineAn anti-inflammatory drug used to treat Crohn's disease and rheumatoid arthritis.
DB01032ProbenecidA medication used to treat gouty arthritis, tophaceous gout, and hyperuricemia.
DB01119DiazoxideA non diuretic benzothiadiazine indicated for the management of hypoglycemia in patients who produce an excess of insulin caused by a variety of conditions.
DB01264DarunavirA HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.
DB01298SulfacytineUsed orally in the treatment of acute urinary tract infections.
DB01299SulfadoxineA long acting sulfonamide used for the treatment or prevention of malaria.
DB01324PolythiazideA thiazide diuretic used in the management of hypertension and treatment of edema.
DB01582SulfamethazineAn antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections.
DB06290SimeprevirA direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4.
DB13547SulfatolamideNot Annotated
DB01015SulfamethoxazoleAn sulfonamide antibiotic is used to treat bronchitis, prostatitis, and urinary tract infections.
DB01144DiclofenamideA carbonic anhydrase inhibitor used for the management of open-angle and secondary glaucoma, as well as acute angle-closure glaucoma in delayed pre-operative setting requiring a reduction in intraocular pressure.
DB00259SulfanilamideA sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans.
DB00232MethyclothiazideA diuretic drug used to treat hypertension and edema caused by heart failure, renal conditions, treatment with corticosteroids, and estrogen therapy.
DB00695FurosemideA loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension.
DB00887BumetanideA sulfamyl diuretic used to treat edema in congestive heart failure, hepatic and renal disease, and nephrotic syndrome.
DB00999HydrochlorothiazideA thiazide diuretic used to treat edema associated with a number of conditions, and hypertension.
DB01581SulfamerazineAn antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections.
DB00203SildenafilA phosphodiesterase inhibitor used for the treatment of erectile dysfunction.
DB00606CyclothiazideCyclothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either...
DB00634SulfacetamideA corticosteroid used to treat inflammatory ocular conditions and acne vulgaris.
DB00808IndapamideA thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure.
DB00880ChlorothiazideA thiazide diuretic used to treat hypertension and edema in congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy.
DB00891SulfapyridineA sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum.
DB06821SulfameterLong acting sulfonamide used in leprosy, urinary, and respiratory tract infections.
DB08798SulfamoxoleFor the treatment of bacterial infection.
DB00482CelecoxibAn NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis.
DB00664SulfametopyrazineFor the treatment of urinary tract infection and chronic bronchitis.
DB00311EthoxzolamideFor use in the treatment of duodenal ulcers, as a diuretic, and in the treatment of glaucoma, and may also be useful in the treatment of seizures associated with epilepsy.
DB00359SulfadiazineA sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid.
DB01021TrichlormethiazideUsed in the treatment of oedema (including that associated with heart failure) and hypertension.
DB01098RosuvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
DB04707HydroxyfasudilNot Available
DB06150SulfadimethoxineFor use in the treatment of infections.
DB079965-(2-methylpiperazine-1-sulfonyl)isoquinolineNot Available
DB08961AzosemideAzosemide is a loop diuretic used to treat hypertension, edema, and ascites.
DB11389ClorsulonNot Annotated
DB11461SulfachlorpyridazineA sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.
DB11462SulfaethoxypyridazineNot Annotated
DB11463SulfanitranNot Annotated
DB11464SulfaquinoxalineSulfaquinoxaline is a veterinary medicine which can be given to cattle and sheep to treat coccidiosis.It is available in Pakistan with Sanna Laboratories in combination with Amprolium and Vitamin K...
DB12051SetrobuvirSetrobuvir has been used in trials studying the treatment of Hepatitis C, Chronic.
DB12921ChlorsulfaquinoxalineChlorsulfaquinoxaline has been used in trials studying the treatment of Lung Cancer and Colorectal Cancer.
DB13283SulfaisodimidineSulfaisodimidine also called sulfisomidine is an antibacterial product that has been studied for the treatment of urinary tract infections in the 1950s, however, it is unclear whether this drug has...
DB13405MefrusideNot Annotated
DB13430MebutizideNot Annotated
DB13532CyclopenthiazideCyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients...
DB13699SulfathioureaNot Annotated
DB13773SulfamethoxypyridazineNot Annotated
DB13792ClopamideClopamide is an oral diuretic agent with antihypertensive activity. Like thiazide diuretics, it has an aromatic sulfonamide base but with no double-ring structure.
DB13803XipamideNot Annotated
DB14033Acetyl sulfisoxazoleAcute, recurrent or chronic urinary tract infections (primarily pyelonephritis, pyelitis and cystitis) due to susceptible organisms (usually Escherichia coli, Klebsiella-Enterobacter, staphylococcus, Proteus mirabilis and, less frequently, Proteus vulgaris) in the...
DB00214TorasemideA diuretic used to treat hypertension and edema associated with heart failure, renal failure, or liver disease.
DB01382GlymidineGlycodiazine is used concomitantly with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus.
DB02925PiretanidePiretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine...
DB13214SulfadicramideNot Annotated
DB13284MeticraneMeticrane is a diuretic medication. It has been marketed in Japan under the trade name Arresten and is used to lower blood pressure .
DB13320SulfaperinNot Annotated
DB13485SulfametomidineNot Annotated
DB13556SulfamazoneNot Annotated
DB13617ClorexoloneNot Annotated
DB13663ClofenamideNot Annotated
DB13708FenquizoneNot Annotated
DB01325QuinethazoneUsed to treat hypertension.
DB00819AcetazolamideA cardiac anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma.
DB00909ZonisamideA sulfonamide anticonvulsant used to treat partial seizures.
DB14708TosylchloramideTosylchloramide, also known as chloramine-T, is a chlorinated and deprotonated sulfonamide used as a mild disinfectant. It is not stable in the water dissolved form.
DB08162FasudilFasudil has been investigated in Carotid Stenosis.
DB00559BosentanA dual endothelin receptor antagonist used to treat pulmonary arterial hypertension.
DB00706TamsulosinAn alpha-1A and alpha-1B adrenergic receptor antagonist used to treat benign prostatic hyperplasia, ureteral stones, prostatitis, and female voiding dysfunction.
DB08881VemurafenibA kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation.
DrugDrug NameTargetType
DB00263SulfisoxazoleDihydropteroate synthasetarget
DB00263SulfisoxazoleCytochrome P450 2C9enzyme
DB00576SulfamethizoleDihydropteroate synthasetarget
DB00576SulfamethizoleSerum albumincarrier
DB00576SulfamethizoleCytochrome P450 2C9enzyme
DB05245Silver sulfadiazineDNAtarget
DB06729SulfaphenazoleCytochrome P450 2C9enzyme
DB06729SulfaphenazoleCytochrome P450 2B6enzyme
DB06729SulfaphenazoleCytochrome P450 2C8enzyme
DB06729SulfaphenazoleCytochrome P450 2D6enzyme
DB06729SulfaphenazoleDihydropteroate synthasetarget
DB06795MafenideCarbonic anhydrase 6target
DB06147SulfathiazoleDihydropteroate synthetasetarget
DB06147SulfathiazoleCytochrome P450 19A1enzyme
DB00310ChlorthalidoneSolute carrier family 12 member 1target
DB00310ChlorthalidoneSerum albumincarrier
DB00310ChlorthalidoneCarbonic anhydrase 1target
DB00436BendroflumethiazideSolute carrier family 12 member 3target
DB00436BendroflumethiazideCarbonic anhydrase 1target
DB00436BendroflumethiazideCarbonic anhydrase 2target
DB00436BendroflumethiazideCarbonic anhydrase 4target
DB00436BendroflumethiazideCalcium-activated potassium channel subunit alpha-1target
DB00436BendroflumethiazideThiopurine S-methyltransferaseenzyme
DB00524MetolazoneSolute carrier family 12 member 3target
DB00562BenzthiazideSolute carrier family 12 member 3target
DB00562BenzthiazideCarbonic anhydrase 1target
DB00562BenzthiazideCarbonic anhydrase 2target
DB00562BenzthiazideCarbonic anhydrase 4target
DB00562BenzthiazideCarbonic anhydrase 9target
DB00562BenzthiazideCarbonic anhydrase 12target
DB00669Sumatriptan5-hydroxytryptamine receptor 1Dtarget
DB00669Sumatriptan5-hydroxytryptamine receptor 1Btarget
DB00669Sumatriptan5-hydroxytryptamine receptor 1Ftarget
DB00669SumatriptanAmine oxidase [flavin-containing] Aenzyme
DB00669Sumatriptan5-hydroxytryptamine receptor 1Atarget
DB00669SumatriptanSolute carrier organic anion transporter family member 1A2transporter
DB00669SumatriptanP-glycoprotein 1transporter
DB00669SumatriptanATP-binding cassette sub-family G member 2transporter
DB00669SumatriptanSolute carrier organic anion transporter family member 1B1transporter
DB00774HydroflumethiazideSolute carrier family 12 member 1target
DB00774HydroflumethiazideSodium/potassium-transporting ATPase subunit alpha-1target
DB00774HydroflumethiazideCarbonic anhydrase 4target
DB00774HydroflumethiazideCalcium-activated potassium channel subunit alpha-1target
DB00774HydroflumethiazideCarbonic anhydrase 2target
DB00774HydroflumethiazideCarbonic anhydrase 1target
DB00774HydroflumethiazideCarbonic anhydrase 9target
DB00774HydroflumethiazideCarbonic anhydrase 12target
DB00795SulfasalazineAcetyl-CoA acetyltransferase, mitochondrialtarget
DB00795SulfasalazineCystine/glutamate transportertarget
DB00795SulfasalazineATP-binding cassette sub-family G member 2transporter
DB00795SulfasalazineCanalicular multispecific organic anion transporter 1transporter
DB00795SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
DB00795SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00795SulfasalazineProstaglandin G/H synthase 2target
DB00795SulfasalazinePeroxisome proliferator-activated receptor gammatarget
DB00795SulfasalazineProstaglandin G/H synthase 1target
DB00795SulfasalazineArachidonate 5-lipoxygenasetarget
DB00795SulfasalazineProton-coupled folate transportertransporter
DB00795SulfasalazineThromboxane-A synthasetarget
DB00795SulfasalazinePhospholipase A2target
DB00795SulfasalazineSolute carrier organic anion transporter family member 1B1transporter
DB00795SulfasalazineSolute carrier organic anion transporter family member 1B3transporter
DB00795SulfasalazineSolute carrier organic anion transporter family member 2B1transporter
DB01032ProbenecidSolute carrier family 22 member 8target
DB01032ProbenecidSolute carrier family 22 member 11target
DB01032ProbenecidSerum albumincarrier
DB01032ProbenecidSolute carrier family 22 member 2transporter
DB01032ProbenecidSolute carrier family 22 member 1transporter
DB01032ProbenecidCanalicular multispecific organic anion transporter 2transporter
DB01032ProbenecidMultidrug resistance-associated protein 4transporter
DB01032ProbenecidMultidrug resistance-associated protein 5transporter
DB01032ProbenecidMonocarboxylate transporter 2transporter
DB01032ProbenecidSolute carrier family 22 member 5transporter
DB01032ProbenecidMultidrug resistance-associated protein 6transporter
DB01032ProbenecidMultidrug resistance-associated protein 1transporter
DB01032ProbenecidSolute carrier organic anion transporter family member 1A2transporter
DB01032ProbenecidMonocarboxylate transporter 1transporter
DB01032ProbenecidSodium/bile acid cotransportertransporter
DB01032ProbenecidSolute carrier family 22 member 6transporter
DB01032ProbenecidSolute carrier family 22 member 10transporter
DB01032ProbenecidSolute carrier family 22 member 8transporter
DB01032ProbenecidCanalicular multispecific organic anion transporter 1transporter
DB01032ProbenecidATP-binding cassette sub-family C member 11transporter
DB01032ProbenecidSolute carrier family 22 member 11transporter
DB01032ProbenecidSolute carrier organic anion transporter family member 1C1transporter
DB01032ProbenecidSolute carrier family 22 member 7transporter
DB01032ProbenecidSolute carrier family 22 member 6target
DB01032ProbenecidPannexin-1target
DB01032ProbenecidCytochrome P450 2C8enzyme
DB01032ProbenecidCytochrome P450 3A4enzyme
DB01032ProbenecidSolute carrier family 22 member 12transporter
DB01032ProbenecidSolute carrier family 2, facilitated glucose transporter member 9transporter
DB01032ProbenecidTaste receptor type 2 member 16target
DB01032ProbenecidUDP-glucuronosyltransferase 1-1enzyme
DB01032ProbenecidCytochrome P450 2C9enzyme
DB01119DiazoxideSolute carrier family 12 member 3target
DB01119DiazoxideCarbonic anhydrase 1target
DB01119DiazoxideCarbonic anhydrase 2target
DB01119DiazoxideCalcium-activated potassium channel subunit alpha-1target
DB01119DiazoxideSodium/potassium-transporting ATPase subunit alpha-1target
DB01119DiazoxideATP-sensitive inward rectifier potassium channel 11target
DB01119DiazoxideGlutamine synthetaseenzyme
DB01264DarunavirHuman immunodeficiency virus type 1 proteasetarget
DB01264DarunavirCytochrome P450 3A4enzyme
DB01264DarunavirSolute carrier organic anion transporter family member 1B1transporter
DB01264DarunavirP-glycoprotein 1transporter
DB01298SulfacytineDihydropteroate synthasetarget
DB01299SulfadoxineDihydropteroate synthetasetarget
DB01299SulfadoxineBifunctional dihydrofolate reductase-thymidylate synthasetarget
DB01324PolythiazideSolute carrier family 12 member 3target
DB01582SulfamethazineDihydropteroate synthasetarget
DB01582SulfamethazineSerum albumincarrier
DB01582SulfamethazineArylamine N-acetyltransferaseenzyme
DB06290SimeprevirNS3 proteasetarget
DB06290SimeprevirSerum albumincarrier
DB06290SimeprevirCytochrome P450 1A2enzyme
DB06290SimeprevirP-glycoprotein 1transporter
DB06290SimeprevirSolute carrier organic anion transporter family member 1B1transporter
DB06290SimeprevirSolute carrier organic anion transporter family member 1B3transporter
DB06290SimeprevirCytochrome P450 3A4enzyme
DB06290SimeprevirCanalicular multispecific organic anion transporter 1transporter
DB06290SimeprevirATP-binding cassette sub-family G member 2transporter
DB06290SimeprevirSolute carrier organic anion transporter family member 2B1transporter
DB06290SimeprevirSodium/bile acid cotransportertransporter
DB06290SimeprevirBile salt export pumptransporter
DB01015SulfamethoxazoleCytochrome P450 2C9enzyme
DB01015SulfamethoxazoleSerum albumincarrier
DB01015SulfamethoxazoleArylamine N-acetyltransferase 1enzyme
DB01015SulfamethoxazoleArylamine N-acetyltransferase 2enzyme
DB01015SulfamethoxazoleProstaglandin G/H synthase 1enzyme
DB01015SulfamethoxazoleUDP-glucuronosyltransferase 1-9enzyme
DB01015SulfamethoxazoleDihydropteroate synthasetarget
DB01015SulfamethoxazoleCytochrome P450 2C8enzyme
DB01015SulfamethoxazoleCytochrome P450 3A4enzyme
DB01015SulfamethoxazoleGlutathione S-transferase Ptarget
DB01015SulfamethoxazoleBile salt export pumptransporter
DB01144DiclofenamideCarbonic anhydrase 1target
DB01144DiclofenamideCarbonic anhydrase 4target
DB01144DiclofenamideCarbonic anhydrase 2target
DB01144DiclofenamideCarbonic anhydrase 7target
DB01144DiclofenamideCarbonic anhydrase 3target
DB00259SulfanilamideDihydropteroate synthasetarget
DB00259SulfanilamideCytochrome P450 2C19enzyme
DB00259SulfanilamideCytochrome P450 2D6enzyme
DB00259SulfanilamideCytochrome P450 2E1enzyme
DB00259SulfanilamideCytochrome P450 3A4enzyme
DB00232MethyclothiazideSolute carrier family 12 member 1target
DB00232MethyclothiazideCarbonic anhydrase 4target
DB00232MethyclothiazideCarbonic anhydrase 2target
DB00232MethyclothiazideCarbonic anhydrase 1target
DB00695FurosemideSolute carrier family 12 member 1target
DB00695FurosemideSerum albumincarrier
DB00695FurosemideSolute carrier family 22 member 6transporter
DB00695FurosemideSolute carrier family 22 member 5transporter
DB00695FurosemideSolute carrier family 22 member 8transporter
DB00695FurosemideCanalicular multispecific organic anion transporter 1transporter
DB00695FurosemideSolute carrier organic anion transporter family member 2A1transporter
DB00695FurosemideSolute carrier family 22 member 11transporter
DB00695Furosemide6-phosphogluconate dehydrogenase, decarboxylatingenzyme
DB00695FurosemideCarbonic anhydrase 2target
DB00695FurosemideUDP-glucuronosyltransferase 1-1enzyme
DB00695FurosemideThyroxine-binding globulincarrier
DB00887BumetanideSolute carrier family 12 member 1target
DB00887BumetanideCystic fibrosis transmembrane conductance regulatortarget
DB00887BumetanideSolute carrier family 12 member 2target
DB00887BumetanideSolute carrier family 12 member 4target
DB00887BumetanideSolute carrier family 12 member 5target
DB00887BumetanideSodium/bile acid cotransportertransporter
DB00887BumetanideSolute carrier family 22 member 6transporter
DB00887BumetanideSolute carrier family 22 member 8transporter
DB00887BumetanideSolute carrier family 22 member 11transporter
DB00887BumetanideSolute carrier family 22 member 7transporter
DB00887BumetanideSolute carrier organic anion transporter family member 1A2transporter
DB00887BumetanideProstaglandin G/H synthase 2enzyme
DB00999HydrochlorothiazideSolute carrier family 12 member 3target
DB00999HydrochlorothiazideSolute carrier family 22 member 6transporter
DB00999HydrochlorothiazideCalcium-activated potassium channel subunit alpha-1target
DB00999HydrochlorothiazideSerum albumincarrier
DB00999HydrochlorothiazideSolute carrier family 22 member 11transporter
DB00999HydrochlorothiazideMultidrug resistance-associated protein 4transporter
DB00999HydrochlorothiazideSolute carrier family 22 member 8transporter
DB01581SulfamerazineDihydropteroate synthasetarget
DB01581SulfamerazineSerum albumincarrier
DB00203SildenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00203SildenafilCytochrome P450 2C9enzyme
DB00203SildenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00203SildenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00203SildenafilCytochrome P450 3A4enzyme
DB00203SildenafilCytochrome P450 3A5enzyme
DB00203SildenafilCytochrome P450 3A7enzyme
DB00203SildenafilMultidrug resistance-associated protein 4transporter
DB00203SildenafilMultidrug resistance-associated protein 5transporter
DB00203SildenafilMultidrug resistance-associated protein 7transporter
DB00203SildenafilCytochrome P450 2C19enzyme
DB00203SildenafilCytochrome P450 2D6enzyme
DB00203SildenafilCytochrome P450 2E1enzyme
DB00203SildenafilSolute carrier organic anion transporter family member 1B1transporter
DB00203SildenafilP-glycoprotein 1transporter
DB00606CyclothiazideSodium/potassium-transporting ATPase subunit gammatarget
DB00606CyclothiazideCarbonic anhydrase 1target
DB00606CyclothiazideCarbonic anhydrase 2target
DB00606CyclothiazideCarbonic anhydrase 4target
DB00606CyclothiazideSolute carrier family 22 member 6transporter
DB00606CyclothiazideSecreted frizzled-related protein 4target
DB00634SulfacetamideDihydropteroate synthasetarget
DB00634SulfacetamideDihydropteroate synthase type-1target
DB00634SulfacetamideFolic acid synthesis protein FOL1target
DB00808IndapamideCytochrome P450 3A4enzyme
DB00808IndapamideSolute carrier family 12 member 3target
DB00880ChlorothiazideSolute carrier family 12 member 3target
DB00880ChlorothiazideCarbonic anhydrase 1target
DB00880ChlorothiazideCarbonic anhydrase 2target
DB00880ChlorothiazideSolute carrier family 22 member 6transporter
DB00891SulfapyridineDihydropteroate synthase type-1target
DB00891SulfapyridineCytochrome P450 2C9enzyme
DB06821SulfameterDihydropteroate synthasetarget
DB08798SulfamoxoleDihydropteroate synthetasetarget
DB08798SulfamoxoleCytochrome P450 2C9enzyme
DB00482CelecoxibProstaglandin G/H synthase 2target
DB00482Celecoxib3-phosphoinositide-dependent protein kinase 1target
DB00482CelecoxibCytochrome P450 2C9enzyme
DB00482CelecoxibCytochrome P450 2D6enzyme
DB00482CelecoxibMultidrug resistance-associated protein 4transporter
DB00482CelecoxibCytochrome P450 3A4enzyme
DB00482CelecoxibCytochrome P450 2C8enzyme
DB00482CelecoxibCarbonic anhydrase 2target
DB00482CelecoxibCarbonic anhydrase 3target
DB00482CelecoxibBile salt export pumptransporter
DB00482CelecoxibCadherin-11target
DB00482CelecoxibP-glycoprotein 1transporter
DB00482CelecoxibATP-binding cassette sub-family G member 2transporter
DB00664SulfametopyrazineDihydropteroate synthetasetarget
DB00311EthoxzolamideCarbonic anhydrase 1target
DB00311EthoxzolamideSolute carrier family 22 member 6transporter
DB00311EthoxzolamideCarbonic anhydrase 2target
DB00311EthoxzolamideCarbonic anhydrase 4target
DB00311EthoxzolamideCarbonic anhydrase 7target
DB00311EthoxzolamideCarbonic anhydrase 3target
DB00359SulfadiazineCytochrome P450 2C9enzyme
DB00359SulfadiazineDihydropteroate synthetasetarget
DB00359SulfadiazineCytochrome P450 2C8enzyme
DB00359SulfadiazineCytochrome P450 3A4enzyme
DB01021TrichlormethiazideSolute carrier family 12 member 3target
DB01021TrichlormethiazideSodium/potassium-transporting ATPase subunit alpha-1target
DB01021TrichlormethiazideCarbonic anhydrase 4target
DB01021TrichlormethiazideCarbonic anhydrase 2target
DB01021TrichlormethiazideCarbonic anhydrase 1target
DB01021TrichlormethiazideThiopurine S-methyltransferaseenzyme
DB01098Rosuvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB01098RosuvastatinCytochrome P450 2C9enzyme
DB01098RosuvastatinMultidrug resistance-associated protein 4transporter
DB01098RosuvastatinSolute carrier organic anion transporter family member 1A2transporter
DB01098RosuvastatinSolute carrier organic anion transporter family member 1B3transporter
DB01098RosuvastatinSolute carrier organic anion transporter family member 2B1transporter
DB01098RosuvastatinCystine/glutamate transportertransporter
DB01098RosuvastatinSolute carrier organic anion transporter family member 1B1transporter
DB01098RosuvastatinBile salt export pumptransporter
DB01098RosuvastatinATP-binding cassette sub-family G member 2transporter
DB01098RosuvastatinSerum albumincarrier
DB01098RosuvastatinCanalicular multispecific organic anion transporter 1transporter
DB01098RosuvastatinSolute carrier family 22 member 8transporter
DB01098RosuvastatinSodium/bile acid cotransportertransporter
DB01098RosuvastatinIntegrin alpha-Ltarget
DB04707HydroxyfasudilRho-associated protein kinase 1target
DB04707HydroxyfasudilcAMP-dependent protein kinase catalytic subunit alphatarget
DB04707HydroxyfasudilcAMP-dependent protein kinase inhibitor alphatarget
DB06150SulfadimethoxineCytochrome P450 2C9enzyme
DB079965-(2-methylpiperazine-1-sulfonyl)isoquinolinecAMP-dependent protein kinase catalytic subunit alphatarget
DB079965-(2-methylpiperazine-1-sulfonyl)isoquinolinecAMP-dependent protein kinase inhibitor alphatarget
DB14033Acetyl sulfisoxazoleDihydropteroate synthasetarget
DB14033Acetyl sulfisoxazoleCytochrome P450 2C9enzyme
DB00214TorasemideSolute carrier family 12 member 1target
DB00214TorasemideCytochrome P450 2C8enzyme
DB00214TorasemideCytochrome P450 2C9enzyme
DB00214TorasemideSolute carrier organic anion transporter family member 1B1transporter
DB00214TorasemideSolute carrier family 12 member 2target
DB00214TorasemideSerum albumincarrier
DB01382GlymidineATP-sensitive inward rectifier potassium channel 1target
DB01382GlymidineATP-binding cassette sub-family C member 8target
DB02925PiretanideSolute carrier family 12 member 1target
DB01325QuinethazoneCarbonic anhydrase 1target
DB01325QuinethazoneCarbonic anhydrase 2target
DB01325QuinethazoneSolute carrier family 12 member 1target
DB01325QuinethazoneSolute carrier family 12 member 2target
DB01325QuinethazoneSolute carrier family 12 member 3target
DB00819AcetazolamideCarbonic anhydrase 1target
DB00819AcetazolamideAquaporin-1target
DB00819AcetazolamideCarbonic anhydrase 14target
DB00819AcetazolamideSolute carrier family 22 member 6transporter
DB00819AcetazolamideCarbonic anhydrase 2target
DB00819AcetazolamideCarbonic anhydrase 3target
DB00819AcetazolamideCarbonic anhydrase 4target
DB00819AcetazolamideCytochrome P450 3A4enzyme
DB00819AcetazolamideCarbonic anhydrase 7target
DB00819AcetazolamideCarbonic anhydrase 12target
DB00909ZonisamideSodium channel protein type 1 subunit alphatarget
DB00909ZonisamideCarbonic anhydrase 1target
DB00909ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00909ZonisamideCytochrome P450 3A4enzyme
DB00909ZonisamideAldehyde oxidaseenzyme
DB00909ZonisamideAmine oxidase [flavin-containing] Btarget
DB00909ZonisamideCarbonic anhydrase 2target
DB00909ZonisamideCarbonic anhydrase 3target
DB00909ZonisamideCarbonic anhydrase 4target
DB00909ZonisamideCarbonic anhydrase 5A, mitochondrialtarget
DB00909ZonisamideCarbonic anhydrase 5B, mitochondrialtarget
DB00909ZonisamideCarbonic anhydrase 6target
DB00909ZonisamideCarbonic anhydrase 7target
DB00909ZonisamideCarbonic anhydrase-related proteintarget
DB00909ZonisamideCarbonic anhydrase 9target
DB00909ZonisamideCarbonic anhydrase-related protein 10target
DB00909ZonisamideCarbonic anhydrase-related protein 11target
DB00909ZonisamideCarbonic anhydrase 12target
DB00909ZonisamideCarbonic anhydrase 13target
DB00909ZonisamideCarbonic anhydrase 14target
DB00909ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB00909ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB00909ZonisamideSodium channel protein type 2 subunit alphatarget
DB00909ZonisamideSodium channel protein type 3 subunit alphatarget
DB00909ZonisamideSodium channel protein type 4 subunit alphatarget
DB00909ZonisamideSodium channel protein type 5 subunit alphatarget
DB00909ZonisamideSodium channel protein type 9 subunit alphatarget
DB00909ZonisamideSodium channel protein type 11 subunit alphatarget
DB00909ZonisamideSodium channel subunit beta-1target
DB00909ZonisamideSodium channel subunit beta-2target
DB00909ZonisamideSodium channel subunit beta-3target
DB00909ZonisamideSodium channel subunit beta-4target
DB00909ZonisamideAmine oxidase [flavin-containing] Atarget
DB00909ZonisamideCytochrome P450 2C19enzyme
DB00909ZonisamideUDP-glucuronosyltransferase 1-1enzyme
DB00909ZonisamideCytochrome P450 3A5enzyme
DB08162FasudilcAMP-dependent protein kinase inhibitor alphatarget
DB08162FasudilcAMP-dependent protein kinase catalytic subunit alphatarget
DB08162FasudilRho-associated protein kinase 1target
DB08162FasudilRho-associated protein kinase 2target
DB00559BosentanEndothelin B receptortarget
DB00559BosentanEndothelin-1 receptortarget
DB00559BosentanCytochrome P450 3A4enzyme
DB00559BosentanCytochrome P450 2C9enzyme
DB00559BosentanBile salt export pumptransporter
DB00706TamsulosinAlpha-1A adrenergic receptortarget
DB00706TamsulosinAlpha-1D adrenergic receptortarget
DB00706TamsulosinAlpha-1B adrenergic receptortarget
DB00706TamsulosinAlpha-1-acid glycoprotein 1carrier
DB00706TamsulosinCytochrome P450 2D6enzyme
DB00706TamsulosinCytochrome P450 3A4enzyme
DB08881VemurafenibSerum albumincarrier
DB08881VemurafenibAlpha-1-acid glycoprotein 1carrier
DB08881VemurafenibCytochrome P450 1A2enzyme
DB08881VemurafenibCytochrome P450 2D6enzyme
DB08881VemurafenibCytochrome P450 3A4enzyme
DB08881VemurafenibSerine/threonine-protein kinase B-raftarget
DB08881VemurafenibMultidrug resistance-associated protein 1transporter
DB08881VemurafenibATP-binding cassette sub-family G member 2transporter
DB08881VemurafenibCytochrome P450 2C9enzyme
DB08881VemurafenibCytochrome P450 2C8enzyme
DB08881VemurafenibCytochrome P450 2B6enzyme