Purpura, Thrombocytopenic, Idiopathic

Also known as: Idiopathic Thrombocytopenia Purpura / ITP / Idiopathic Thrombocytopenic Purpura (ITP) / Idiopathic Thrombocytopenic Purpura / Werlhof's disease / Immune thrombocytopenic purpura / Hemorrhagic (thrombocytopenic) purpura / Werlhof's syndrome / Idiopathic purpura

DrugDrug NameDrug Description
DB01380Cortisone acetateA steroid hormone used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and endocrine disorders associated with inadequate production of steroid hormones.
DB00091CyclosporineA steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis.
DB01234DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
DB00741HydrocortisoneA glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
DB00959MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
DB00860PrednisoloneA glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
DB00635PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
DrugDrug NameTargetType
DB01380Cortisone acetateGlucocorticoid receptortarget
DB01380Cortisone acetateCytochrome P450 3A4enzyme
DB01380Cortisone acetateCytochrome P450 3A5enzyme
DB00091CyclosporineCalcium signal-modulating cyclophilin ligandtarget
DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase Atarget
DB00091CyclosporineCalcineurin subunit B type 2target
DB00091CyclosporineCytochrome P450 3A5enzyme
DB00091CyclosporineCytochrome P450 3A4enzyme
DB00091CyclosporineCytochrome P450 3A7enzyme
DB00091CyclosporineP-glycoprotein 1transporter
DB00091CyclosporineCanalicular multispecific organic anion transporter 2transporter
DB00091CyclosporineBile salt export pumptransporter
DB00091CyclosporineSolute carrier organic anion transporter family member 1A2transporter
DB00091CyclosporineIleal sodium/bile acid cotransportertransporter
DB00091CyclosporineSodium/bile acid cotransportertransporter
DB00091CyclosporineSolute carrier family 22 member 6transporter
DB00091CyclosporineMultidrug resistance-associated protein 7transporter
DB00091CyclosporineCanalicular multispecific organic anion transporter 1transporter
DB00091CyclosporineATP-binding cassette sub-family G member 2transporter
DB00091CyclosporineSolute carrier organic anion transporter family member 1B1transporter
DB00091CyclosporineCytochrome P450 2C19enzyme
DB00091CyclosporineCytochrome P450 2C9enzyme
DB00091CyclosporineCytochrome P450 2D6enzyme
DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
DB00091CyclosporineSolute carrier organic anion transporter family member 1B3transporter
DB01234DexamethasoneGlucocorticoid receptortarget
DB01234DexamethasoneAnnexin A1target
DB01234DexamethasoneNitric oxide synthase, inducibletarget
DB01234DexamethasoneNuclear receptor subfamily 0 group B member 1target
DB01234DexamethasoneCytochrome P450 3A4enzyme
DB01234DexamethasoneCytochrome P450 3A5enzyme
DB01234DexamethasoneCytochrome P450 3A7enzyme
DB01234DexamethasoneBile salt export pumptransporter
DB01234DexamethasoneP-glycoprotein 1transporter
DB01234DexamethasoneCanalicular multispecific organic anion transporter 1transporter
DB01234DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DB01234DexamethasoneATP-binding cassette sub-family G member 2transporter
DB01234DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB01234DexamethasoneCytochrome P450 1A1enzyme
DB01234DexamethasoneCytochrome P450 2A6enzyme
DB01234DexamethasoneCytochrome P450 2B6enzyme
DB01234DexamethasoneCytochrome P450 2C19enzyme
DB01234DexamethasoneCytochrome P450 2C8enzyme
DB01234DexamethasoneCytochrome P450 2E1enzyme
DB01234DexamethasoneCytochrome P450 3A43enzyme
DB01234DexamethasoneCytochrome P450 4A11enzyme
DB01234DexamethasoneNuclear receptor subfamily 1 group I member 2target
DB01234DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DB00741HydrocortisoneAnnexin A1target
DB00741HydrocortisoneGlucocorticoid receptortarget
DB00741HydrocortisoneSex hormone-binding globulincarrier
DB00741HydrocortisoneCytochrome P450 3A4enzyme
DB00741HydrocortisoneCytochrome P450 3A5enzyme
DB00741HydrocortisoneCytochrome P450 3A7enzyme
DB00741HydrocortisoneP-glycoprotein 1transporter
DB00741HydrocortisoneSolute carrier organic anion transporter family member 1A2transporter
DB00741HydrocortisoneCytochrome P450 11B1, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 11B2, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 2C8enzyme
DB00741HydrocortisoneCorticosteroid-binding globulincarrier
DB00741HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB00741Hydrocortisone3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB00741HydrocortisoneSolute carrier family 22 member 8transporter
DB00959MethylprednisoloneGlucocorticoid receptortarget
DB00959MethylprednisoloneCytochrome P450 3A4enzyme
DB00959MethylprednisoloneP-glycoprotein 1transporter
DB00860PrednisoloneCorticosteroid-binding globulincarrier
DB00860PrednisoloneCytochrome P450 3A4enzyme
DB00860PrednisoloneGlucocorticoid receptortarget
DB00860PrednisoloneSolute carrier organic anion transporter family member 1A2transporter
DB00860PrednisoloneP-glycoprotein 1transporter
DB00860PrednisoloneSerum albumincarrier
DB00635PrednisoneGlucocorticoid receptortarget
DB00635PrednisoneCytochrome P450 3A4enzyme
DB00635PrednisoneP-glycoprotein 1transporter
DB00635PrednisoneSolute carrier organic anion transporter family member 1A2transporter
DB00635PrednisoneCytochrome P450 2C19enzyme
DB00635PrednisoneSerum albumincarrier
DB00635PrednisoneCorticosteroid 11-beta-dehydrogenase isozyme 1target
DB00635PrednisoneCytochrome P450 3A5enzyme
DrugDrug NamePhaseStatusCount
DB11995Avatrombopag1Completed4
DB15301Bevifimod1Terminated1
DB00537Ciprofloxacin1Completed1
DB00091Cyclosporine1Completed2
DB06210Eltrombopag1Completed6
DB15397GMA-1611Terminated1
DB00661Verapamil1Completed1
DB00073Rituximab1 / 2Completed1
DB05332Romiplostim1 / 2Completed1
DB00877Sirolimus1 / 2Active Not Recruiting1
DB05656Veltuzumab1 / 2Active Not Recruiting1
DB11995Avatrombopag2Completed2
DB06210Eltrombopag2Completed2
DB12010Fostamatinib2Completed1
DB00028Immune globulin human2Completed2
DB00073Rituximab2Completed3
DB00073Rituximab2Withdrawn1
DB05332Romiplostim2Completed3
DB00087Alemtuzumab2 / 3Completed1
DB12330Blisibimod2 / 3Withdrawn1
DB01234Dexamethasone2 / 3Recruiting1
DB00635Prednisone2 / 3Recruiting1
DB00073Rituximab2 / 3Completed1
DB11995Avatrombopag3Terminated1
DB00188Bortezomib3Not Yet Recruiting1
DB01262Decitabine3Not Yet Recruiting1
DB01234Dexamethasone3Completed5
DB01234Dexamethasone3Not Yet Recruiting1
DB01234Dexamethasone3Recruiting1
DB01234Dexamethasone3Withdrawn2
DB06210Eltrombopag3Completed5
DB06210Eltrombopag3Terminated1
DB00741Hydrocortisone3Not Yet Recruiting1
DB00028Immune globulin human3Completed2
DB00860Prednisolone3Completed1
DB00635Prednisone3Completed1
DB00073Rituximab3Completed4
DB00073Rituximab3Not Yet Recruiting1
DB00073Rituximab3Recruiting1
DB00073Rituximab3Withdrawn1
DB05332Romiplostim3Completed7
DB06534Thrombopoietin3Completed3
DB06534Thrombopoietin3Unknown Status1
DB06534Thrombopoietin3Withdrawn1
DB00755Tretinoin3Withdrawn1
DB01234Dexamethasone4Completed1
DB06210Eltrombopag4Completed1
DB00635Prednisone4Completed1
DB00073Rituximab4Completed1
DB05332Romiplostim4Completed1
DB00993AzathioprineNot AvailableRecruiting1
DB06210EltrombopagNot AvailableRecruiting1
DB06210EltrombopagNot AvailableTerminated1
DB00688Mycophenolate mofetilNot AvailableRecruiting1
DB00073RituximabNot AvailableRecruiting1
DB00073RituximabNot AvailableWithdrawn1