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Displaying drugs 26 - 50 of 10824 in total
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual,...
Approved
Investigational
Vet approved
Matched Synonyms: … Magnesium sulfate (1:1) …
Matched Salts cas: … 14168-73-1
Matched Products: … MINOXID 20 ... OTSU - MgSO4 20 ... INFUSAN MgSO4 20% …
Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic.
Approved
Matched Synonyms: … R-(+)-ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate ... (R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic acid ethyl ester ... (+)-ethyl 1-(α-methylbenzyl)imidazole-5-carboxylate …
Matched Iupac: … ethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ETOMIDATE-LIPURO INJECTION 20 mg/10 ml …
Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms. It was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice.
Approved
Withdrawn
Matched Synonyms: … 1-(p-Fluorobenzyl)-2-((1-(2-(p-methoxyphenyl)ethyl)piperid-4-yl)amino)benzimidazole ... 1-(p-Fluorobenzyl)-2-((1-(p-methoxyphenethyl)-4-piperidyl)amino)benzimidazole …
Matched Iupac: … 1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-1,3-benzodiazol-2-amine …
Matched Products: … AZTEMIZOL SUSPENSION 1 MG/ML ... ASTEMIZOL 1 MG/ML SUSPENSION ... ASTEMIZOL SUSPENSION 1 MG./ML. …
Approved
Matched Synonyms: … Ferrous cysteine glycinate chelate (1:2:1) …
Calcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. Calcium carbonate may also...
Approved
Investigational
Matched Synonyms: … Calcium carbonate (1:1) ... Carbonic acid calcium salt (1:1) …
Matched Mixtures name: … PNV Tabs 20-1 ... PNV Tabs 29-1 ... Trinatal Rx 1
Matched Products: … EFERCAL 500 MG EFERVESAN TABLET, 20 ADET ... OSTRAM 1000 MG EFERVESAN TABLET, 20 ADET …
An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues. [PubChem]
Approved
Matched Synonyms: … 2-(1'-Azacyclooctyl)ethylguanidine ... (2-(Octahydro-1-azocinyl)ethyl)guanidine ... (2-(hexahydro-1(2h)-azocinyl)ethyl)guanidine …
Matched Iupac: … N''-[2-(azocan-1-yl)ethyl]guanidine …
Trimetazidine is a piperazine derivative indicated for the symptomatic treatment of stable angina pectoris in patients inadequately controlled or intolerant to first line therapies. Trimetazidine has been studied as a treatment for angina pectoris since the late 1960s.[A233255,A233260] Acidic conditions, caused by anaerobic metabolism and fatty acid oxidation, in response...
Approved
Investigational
Matched Synonyms: … 1-[2,3,4-trimethoxybenzyl] piperazine dihydrochloride …
Matched Iupac: … 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … วาสทินอล 20 มก. ... วาสตาเรล 20 มก. ... AXINOL TABLET 20 MG …
In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Synonyms: … 1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl) …
Matched Iupac: … 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin …
Matched Products: … VEGIRO 100 MG FILM TABLET,1 ADET ... DEGRA 50 MG FILM KAPLI TABLET, 1 ADET ... DEGRA 100 MG FILM KAPLI TABLET, 1 ADET …
Nickel sulfate is used in allergenic testing.
Approved
Experimental
Matched Synonyms: … Nickel sulfate(1:1) …
Fenoterol is an adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic.
Approved
Investigational
Matched Synonyms: … 1-(3,5-dihydroxyphenyl)-1-hydroxy-2-((4-hydroxyphenyl)isopropylamino)ethane ... 5-{1-Hydroxy-2-[2-(4-hydroxy-phenyl)-1-methyl-ethylamino]-ethyl}-benzene-1,3-diol ... 1-(p-hydroxyphenyl)-2-((β-hydroxy-β-(3',5'-dihydroxyphenyl))ethyl)aminopropane …
Matched Iupac: … 5-(1-hydroxy-2-{[1-(4-hydroxyphenyl)propan-2-yl]amino}ethyl)benzene-1,3-diol …
Matched Mixtures name: … NOTECORT 20 MCG / 50 MCG AEROSOL İNHALASYONU, ÇÖZELTİ, 1 ADET ... NOTECORT 20 MCG / 50 MCG AEROSOL İNHALASYONU, ÇÖZELTİ, 3 ADET …
First synthesized in the early 1980s, itraconazole is a broad-spectrum triazole antifungal agent used to treat a variety of infections. It is a 1:1:1:1 racemic mixture of four diastereomers, made up of two enantiomeric pairs, each possessing three chiral centers. Itraconazole was first approved in the US in 1992 and...
Approved
Investigational
Matched Synonyms: … -4-YL)METHOXY)PHENYL)-1-PIPERAZINYL)PHENYL)-2,4-DIHYDRO-2-(1-METHYLPROPYL)- ... (±)-1-SEC-BUTYL-4-(P-(4-(P-(((2R*,4S*)-2-(2,4-DICHLOROPHENYL)-2-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1,3-DIOXOLAN ... -4-YL)METHOXY)PHENYL)-1-PIPERAZINYL)PHENYL)-.DELTA. …
Matched Iupac: … 1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan ... -4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one …
Matched Description: … [A34257] It is a 1:1:1:1 racemic mixture of four diastereomers, made up of two enantiomeric pairs, each …
Matched Mixtures name: … Ciclopirox 3% / Itraconazole 5% / Urea 20% ... Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … FUNGITRAL - ITRACONAZOL 1% SOLUCION ORAL …
Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men for whom oral treatment...
Approved
Investigational
Matched Synonyms: … PGE-1 ... (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid …
Matched Iupac: … 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid …
Matched Products: … JECTERA 20 MCG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 ADET ... JECTERA 10 MCG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 ADET ... CAVERJECT 20 MCG …
A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.
Approved
Matched Synonyms: … 1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsäure ... 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ... 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid …
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Products: … N-20% w/v Oral Solution …
Aminoglycosides, many of which are derived directly from Streptomyces spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as P. aeruginosa is notoriously inherently resistant to...
Approved
Investigational
Matched Synonyms: … -(1-4))-2-deoxy-D-streptamine ... O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl …
Matched Salts cas: … 49842-07-1
Matched Mixtures name: … TOBRAZON %0.3 + %0.1 GÖZ DAMLASI, SÜSPANSİYON, 1 ADET ... TOBRALOT 5 MG+3 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET ... OFTAMYCIN-DX %0.3 + %0.1 STERİL GÖZ DAMLASI, ÇÖZELTİ, 5 ML 1 ADET …
Matched Products: … TOBEL 20 MG/2 ML AMPUL, 1 ADET ... Braun 1 mg/ml Infusionslösung ... TOBEL 20 MG/2 ML AMPUL, 3 ADET …
Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII)....
Approved
Matched Synonyms: … (2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta …
Matched Iupac: … (2S,3aS,6aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydrocyclopenta[ …
Matched Mixtures name: … Lasitace 5 mg/20 mg Kapseln ... Trinomia 100 mg/20 mg/5 mg Hartkapseln ... Trinomia 100 mg/20 mg/10 mg Hartkapseln …
Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms. It is selective for the H1 receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier - this is in contrast to previous first-generation antihistamines, such as diphenhydramine, which readily bind to off-targets...
Approved
Investigational
Matched Synonyms: … 4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethylbenzeneacetic acid …
Matched Iupac: … 2-(4-{1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid …
Matched Description: … [L4269] It is selective for the H1 receptor, carries little-to-no activity at off-targets, …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … MAYFEX 120 MG FILM TABLET, 20 ADET ... MAYFEX 180 MG FILM TABLET, 20 ADET ... FEXOFEN 60 MG FİLM TABLET, 20 ADET …
A nitroimidazole antitrichomonal agent effective against Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia infections.
Approved
Investigational
Matched Synonyms: … 1-(2-(Ethylsulfonyl)ethyl)-2-methyl-5-nitroimidazole …
Matched Iupac: … 1-[2-(ethanesulfonyl)ethyl]-2-methyl-5-nitro-1H-imidazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … TINIDAZOL 20% SUSPENSION ... TINIDAZOL 1 G ... TINIDAZOL 1 G TABLETAS …
Calcium carbimide, sold as the citrate salt, is an alcohol-sensitizing agent. Its effects are similar to the drug disulfiram (Antabuse) in that it interferes with the normal metabolism of alcohol by preventing the breakdown of the metabolic product acetaldehyde. Calcium carbimide was conceived as an alternative for the treatment of...
Approved
Withdrawn
Matched Synonyms: … Cyanamide, calcium salt (1:1) ... methanediimine, calcium salt (1:1) …
Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.[A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date,...
Approved
Investigational
Matched Synonyms: … 1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol …
Matched Iupac: … 1-[4-(2-methoxyethyl)phenoxy]-3-[(propan-2-yl)amino]propan-2-ol …
Matched Description: … Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives …
Matched Categories: … Adrenergic beta-1 Receptor Antagonists …
Matched Products: … Betaloc IV Inj 1 mg/ml ... ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL ,1 AMPUL ... MEPOLEX 5 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 1 AMPUL …
A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)
Approved
Illicit
Matched Synonyms: … 1-phenyl-2-diethylamino-1-propanone ... 2-(diethylamino)-1-phenyl-1-propanone …
Matched Iupac: … 2-(diethylamino)-1-phenylpropan-1-one …
Iron deficiency anemia is a large public health concern worldwide, especially in young children, infants, and women of childbearing age. This type of anemia occurs when iron intake, iron stores, and iron loss do not adequately support the formation of erythrocytes, also known as red blood cells. Ferrous sulfate is...
Approved
Matched Synonyms: … iron sulfate (1:1) …
Matched Mixtures name: … Revival 1 Tab …
An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
Approved
Matched Synonyms: … (±)-5-allyl-1-methyl-5-(1-methyl-2-pentynyl)barbituric acid ... 5-Allyl-1-methyl-5-(1-methyl-pent-2-ynyl)-pyrimidine-2,4,6-trione ... α-DL-1-methyl-5-allyl-5-(1'-methylpentyn-2-yl)barbituric acid …
Matched Iupac: … 5-(hex-3-yn-2-yl)-1-methyl-5-(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Approved
Matched Synonyms: … 1-dodecylazacycloheptan-2-one ... 1-n-dodecylazacycloheptan-2-one ... 1-dodecylhexahydro-2h-azepin-2-one …
Matched Iupac: … 1-dodecylazepan-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
A butyrophenone with general properties similar to those of haloperidol. It is used in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a...
Approved
Vet approved
Matched Synonyms: … 1-(1-(3-(p-fluorobenzoyl)propyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidazolinone ... 1-(1-(4-(p-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidazolinone ... 1-{1-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-1,2,3,6-tetrahydro-pyridin-4-yl}-1,3-dihydro-benzoimidazol-2-one …
Matched Iupac: … 1-{1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydropyridin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2 …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists …
Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures[A186277,A186143] - today it is also widely used to treat neuropathic...
Approved
Investigational
Matched Synonyms: … 1-(Aminomethyl)cyclohexaneacetic acid …
Matched Iupac: … 2-[1-(aminomethyl)cyclohexyl]acetic acid …
Matched Products: … GEMUDA 250MG/5ML ORAL ÇÖZELTI, 470 ML, 1 ŞIŞE ... EVEPTIN 250MG/5ML ORAL ÇÖZELTI, 470 ML, 1 ŞIŞE ... GABATEVA 100 MG KAPSUL, 20 ADET …
Displaying drugs 26 - 50 of 10824 in total