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1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol))

Palmitoyloleoyl-phosphatidylglycerol was a component of Surfaxin, discontinued in 2017, which acted as a surfactant [FDA Label]. The product was meant to compensate for alveolar surfactant deficiency and reduce to likelihood of alveolar collapse leading to acute respiratory collapse.
Approved
Experimental
Matched Synonyms: … 1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)) ... 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol ... 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol …
Matched Name: … 1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)) …
Matched Iupac: … (2,3-dihydroxypropoxy)[(2R)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propoxy]phosphinic acid …
Matched Salts name: … 1-palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)), sodium salt …

Alpha-1-proteinase inhibitor

Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.
Approved
Matched Synonyms: … 122320-05-2 ... .-1 protease inhibitor ... Alfa-1-antitripsina …
Matched Name: … Alpha-1-proteinase inhibitor …
Matched Description: … Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol …
Matched Categories: … Human alpha-1 Proteinase Inhibitor …
Matched Products: … PROLASTIN C 1000 MG IV İNFÜZYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET …

Influenza B virus B/Wisconsin/1/2010 live (attenuated) antigen

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Synonyms: … Influenza B Virus B/wisconsin/1/2010 Live(attenuated) Antigen …
Matched Name: … Influenza B virus B/Wisconsin/1/2010 live (attenuated) antigen …
Matched Description: … then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. …

Hyoscyamine

Hyoscyamine is a tropane alkaloid and the levo-isomer of atropine. It is commonly extracted from plants in the Solanaceae or nightshade family. Research into the action of hyoscyamine in published literature dates back to 1826. Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic...
Approved
Matched Synonyms: … [3(S)-endo]-α-(hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester …
Matched Iupac: … (1R,3S,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl (2S)-3-hydroxy-2-phenylpropanoate …
Matched Salts cas: … 620-61-1 ... 6835-16-1 …
Matched Mixtures name: … Me NaPhos MB Hyo 1 …

Calcium carbimide

Calcium carbimide, sold as the citrate salt, is an alcohol-sensitizing agent. Its effects are similar to the drug disulfiram (Antabuse) in that it interferes with the normal metabolism of alcohol by preventing the breakdown of the metabolic product acetaldehyde. Calcium carbimide was conceived as an alternative for the treatment of...
Approved
Withdrawn
Matched Synonyms: … Cyanamide, calcium salt (1:1) ... methanediimine, calcium salt (1:1) …

Zavegepant

Zavegepant (BHV-3500) is a calcitonin gene-related peptide (CGRP) receptor antagonist. CGRP is released from sensory nerves and acts as a strong vasodilator, and thanks to these properties, it is involved in pain pathways. CGRP receptors are expressed in the central and peripheral nervous system; however, CGRP does not cross the...
Approved
Investigational
Matched Synonyms: … 1-piperidinecarboxamide, 4-(1,2-dihydro-2-oxo-3-quinolinyl)-n-((1r)-1-((7-methyl-1h-indazol-5-yl)methyl ... )-2-(4-(1-methyl-4-piperidinyl)-1-piperazinyl)-2-oxoethyl)- …
Matched Iupac: … -(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide ... N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl]-4 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …

Propranolol

Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.
Approved
Investigational
Matched Synonyms: … 1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol ... 1-((1-Methylethyl)amino)-3-(1-naphthalenyloxy)-2-propanol …
Matched Iupac: … 1-(naphthalen-1-yloxy)-3-[(propan-2-yl)amino]propan-2-ol …
Matched Description: … Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times …
Matched Products: … HEMANGİOL 3,75 MG/ML ORAL ÇÖZELTİ, 1 ADET …

Guanethidine

An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues. [PubChem]
Approved
Matched Synonyms: … 2-(1'-Azacyclooctyl)ethylguanidine ... (2-(Octahydro-1-azocinyl)ethyl)guanidine ... (2-(hexahydro-1(2h)-azocinyl)ethyl)guanidine …
Matched Iupac: … N''-[2-(azocan-1-yl)ethyl]guanidine …
Matched Salts cas: … 645-43-2 …

Ramipril

Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII)....
Approved
Matched Synonyms: … (2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta ... (b)pyrrole-2-carboxylic acid …
Matched Iupac: … (2S,3aS,6aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydrocyclopenta[ ... b]pyrrole-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Efinaconazole

Efinaconazole is a 14 alpha-demethylase inhibitor indicated in the treatment of fungal infection of the nail, known as onychomycosis. It was approved for use in Canada and the USA in 2014 and is marketed by Valeant Pharmaceuticals North America LLC under the name Jublia.
Approved
Matched Synonyms: … (2R,3R)-2-(2,4-Difluorophenyl)-3-(4-methylene-1-piperidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol …
Matched Iupac: … (2R,3R)-2-(2,4-difluorophenyl)-3-(4-methylidenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Ciprofloxacin

Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.
Approved
Investigational
Matched Synonyms: … 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid ... 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ... 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Iupac: … 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Mixtures name: … InfectoCiproCort 3 mg/ml + 0,25 mg/ml Ohrentropfen, Lösung …
Matched Categories: … MATE 1 Inhibitors ... MATE 1 Substrates ... MATE 2 Inhibitors ... Heterocyclic Compounds, 2-Ring …
Matched Products: … NOVAFLOX EYE DROPS 3 mg/ml ... CILOXAN STERILE OPHTHALMIC OINTMENT 3 mg/g ... CIROK INJECTION 2 mg/ml …

Droperidol

A butyrophenone with general properties similar to those of haloperidol. It is used in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a...
Approved
Vet approved
Matched Synonyms: … 1-(1-(3-(p-fluorobenzoyl)propyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidazolinone ... 1-(1-(4-(p-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidazolinone ... 1-{1-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-1,2,3,6-tetrahydro-pyridin-4-yl}-1,3-dihydro-benzoimidazol-2-one …
Matched Iupac: … 1-{1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydropyridin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Adrenergic alpha-1 Receptor Antagonists …

Methohexital

An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
Approved
Matched Synonyms: … 5-Allyl-5-(3-hexyn-2-yl)-1-methylbarbituric acid ... (±)-5-allyl-1-methyl-5-(1-methyl-2-pentynyl)barbituric acid ... α-DL-1-methyl-5-allyl-5-(1'-methylpentyn-2-yl)barbituric acid …
Matched Iupac: … 5-(hex-3-yn-2-yl)-1-methyl-5-(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Mepivacaine

A local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
Approved
Vet approved
Matched Synonyms: … 1-methyl-2',6'-pipecoloxylidide ... (+-)-1-Methyl-2',6'-pipecoloxylidide ... N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide …
Matched Iupac: … N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide …
Matched Mixtures name: … 2% Polocaine Dental With Levonordefrin 1:20,000 ... Scandonest 2% L ... ODONTOCAINA ® 2% …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … MEVIPACAINE HYDROCHLORIDE NEURAL 1% * 2 ML ... Carbocaine 2% ... Carbocaine Liq 2% …

Geraniol

Geraniol is a monoterpene that is found within many essential oils of fruits, vegetables, and herbs including rose oil, citronella, lemongrass, lavender, and other aromatic plants. It is emitted from the flowers of many species of plant and is commonly used by the food, fragrance, and cosmetic industry . Geraniol...
Approved
Experimental
Matched Synonyms: … 2-trans-3,7-Dimethyl-2,6-octadien-1-ol ... (2E)-3,7-dimethylocta-2,6-dien-1-ol ... (E)-3,7-Dimethyl-2,6-octadien-1-ol …
Matched Iupac: … (2E)-3,7-dimethylocta-2,6-dien-1-ol …

Tamoxifen

Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.[A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments.[L7799,L7802] Tamoxifen may no longer be the preferred treatment for these types of cancers...
Approved
Matched Synonyms: … (Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine ... (Z)-2-(para-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine ... 1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene …
Matched Iupac: … (2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine …
Matched Salts cas: … 54965-24-1 …

Teriparatide

Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Synonyms: … PTH 1-34 ... PTH (1-34) …
Matched Products: … Teriparatide Acetate (hPTH (1-34)) …

Ferrous cysteine glycinate

Approved
Matched Synonyms: … Ferrous cysteine glycinate chelate (1:2:1) …
Matched Iupac: … lambda2-iron(2+) (2R)-2-amino-3-sulfanylpropanoic acid 2-aminoacetic acid (2R)-2-amino-3-sulfanidylpropanoate …

Astemizole

Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms. It was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice.
Approved
Withdrawn
Matched Synonyms: … 1-(p-Fluorobenzyl)-2-((1-(2-(p-methoxyphenyl)ethyl)piperid-4-yl)amino)benzimidazole ... 1-(p-Fluorobenzyl)-2-((1-(p-methoxyphenethyl)-4-piperidyl)amino)benzimidazole …
Matched Iupac: … 1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-1,3-benzodiazol-2-amine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … AZTEMIZOL SUSPENSION 1 MG/ML ... ASTEMIZOL 1 MG/ML SUSPENSION ... ASTEMIZOL SUSPENSION 1 MG./ML. …

Zileuton

Leukotrienes are substances that induce numerous biological effects including augmentation of neutrophil and eosinophil migration, neutrophil and monocyte aggregation, leukocyte adhesion, increased capillary permeability, and smooth muscle contraction. These effects contribute to inflammation, edema, mucus secretion, and bronchoconstriction in the airways of asthmatic patients. Zileuton relieves such symptoms through its...
Approved
Investigational
Withdrawn
Matched Synonyms: … (±)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea ... N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea ... N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea …
Matched Iupac: … 1-[1-(1-benzothiophen-2-yl)ethyl]-1-hydroxyurea …

Amantadine

An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and...
Approved
Matched Synonyms: … 1-adamantanamine ... 1-adamantylamine ... 1-aminoadamantane …
Matched Iupac: … adamantan-1-amine …
Matched Mixtures name: … XL-3 VR …

Itraconazole

First synthesized in the early 1980s, itraconazole is a broad-spectrum triazole antifungal agent used to treat a variety of infections. It is a 1:1:1:1 racemic mixture of four diastereomers, made up of two enantiomeric pairs, each possessing three chiral centers. Itraconazole was first approved in the US in 1992 and...
Approved
Investigational
Matched Synonyms: … 3H-1,2,4-TRIAZOL-3-ONE, 4-(4-(4-(4-((2-(2,4-DICHLOROPHENYL)-2-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1,3-DIOXOLAN ... (±)-1-SEC-BUTYL-4-(P-(4-(P-(((2R*,4S*)-2-(2,4-DICHLOROPHENYL)-2-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1,3-DIOXOLAN ... -4-YL)METHOXY)PHENYL)-1-PIPERAZINYL)PHENYL)-2,4-DIHYDRO-2-(1-METHYLPROPYL)- …
Matched Iupac: … 1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan ... -4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one …
Matched Description: … [A34257] It is a 1:1:1:1 racemic mixture of four diastereomers, made up of two enantiomeric pairs, each …
Matched Mixtures name: … Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% ... Ciclopirox 3% / Itraconazole 5% / Urea 20% …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … FUNGITRAL - ITRACONAZOL 1% SOLUCION ORAL …

Laurocapram

Approved
Matched Synonyms: … 1-dodecylazacycloheptan-2-one ... 1-n-dodecylazacycloheptan-2-one ... 1-dodecylhexahydro-2h-azepin-2-one …
Matched Iupac: … 1-dodecylazepan-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Lisinopril

Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.[L8384,L8387,L8390] Lisinopril and captopril are the only ACEIs that are not prodrugs. It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.[A184781,A184808,A184817] ACEIs are commonly used as a...
Approved
Investigational
Matched Synonyms: … (S)-1-(N(2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline ... [N2-[(S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline …
Matched Iupac: … (2S)-1-[(2S)-6-amino-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}hexanoyl]pyrrolidine-2-carboxylic acid …
Matched Products: … Lisinopril Taw Pharma 1 mg/ml Lösung zum Einnehmen …

Tegafur

Tegafur (INN, BAN, USAN) is a prodrug of DB00544 (5-FU), an antineoplastic agent used as the treatment of various cancers such as advanced gastric and colorectal cancers. It is a pyrimidine analogue used in combination therapies as an active chemotherapeutic agent in conjunction with DB09257 and DB03209, or along with...
Approved
Investigational
Matched International brands: … S-1 ... TS-1 ... NKS-1 T …
Matched Synonyms: … 1-(2-Tetrahydrofuryl)-5-fluorouracil …
Matched Iupac: … 5-fluoro-1-(oxolan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 1 - 25 of 12252 in total