Cytochrome P-450 CYP2C8 Inducers

Drugs and compounds that induce the synthesis of CYTOCHROME P-450 CYP2C8.
DrugDrug NameDrug Description
DB01045RifampicinAn antibiotic used to treat several types of mycobacterial infections including Mycobacterium avium complex, leprosy, and in combination with other antibacterials to treat latent or active tuberculosis.
DB00418SecobarbitalA barbiturate used for the short-term treatment of insomnia.
DB14568IvosidenibAn isocitrate dehydrogenase-1 inhibitor used to treat acute myeloid leukemia with a susceptible mutation.
DB00741HydrocortisoneA glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
DB14538Hydrocortisone aceponateFor the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many...
DB14539Hydrocortisone acetateA corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses and ulcerative colitis.
DB14540Hydrocortisone butyrateA corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
DB14541Hydrocortisone cypionateFor the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many...
DB14542Hydrocortisone phosphateFor the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many...
DB14543Hydrocortisone probutateA corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
DB14545Hydrocortisone succinateA corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders.
DB14544Hydrocortisone valerateA corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
DB00615RifabutinAn antibiotic used to treat mycobacterium avium complex disease in patients with HIV.
DB11753RifamycinAn antibacterial used to treat traveler's diarrhea.
DB01201RifapentineAn antibiotic agent used in the treatment of pulmonary tuberculosis.
DB00400GriseofulvinAn antifungal agent used to treat a variety of superficial tinea infections and fungal infections of the fingernails and toes.
DB00503RitonavirAn HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.
DB08912DabrafenibA kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.
DB01241GemfibrozilA lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia.
DB01181IfosfamideAn alkylating and immunosuppressive agent used in chemotherapy for the treatment of cancers, including testicular cancer, ovarian cancer, cervical cancer, osteocarcinoma, bladder cancer, small cell lung cancer, and non-Hodgkin's lymphoma.
DB04868NilotinibA kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib.
DB00531CyclophosphamideA nitrogen mustard used to treat lymphomas, myelomas, leukemia, mycosis fungoides, neuroblastoma, ovarian adenocarcinoma, retinoblastoma, and breast carcinoma.
DB01234DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
DB01032ProbenecidA medication used to treat gouty arthritis, tophaceous gout, and hyperuricemia.
DB09280LumacaftorA protein chaperone used in combination with ivacaftor for the treatment of cystic fibrosis in patients who are homozygous for the F508del mutation in the CFTR gene.
DB06595MidostaurinAn antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL).
DB11633IsavuconazoleIndicated for patients 18 years of age and older for the treatment of invasive aspergillosis [FDA Label]. Indicated for patients 18 years of age and older for the treatment of...
DB00252PhenytoinAn anticonvulsant drug used in the prophylaxis and control of various types of seizures.
DB00908QuinidineA medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
DB01174PhenobarbitalA long-lasting barbiturate and anticonvulsant used in the treatment of all types of seizures, except for absent seizures.
DB11995AvatrombopagA thrombopoietin receptor agonist used to treat thrombocytopenia in patients with chronic liver disease who are scheduled to undergo a procedure.
DB00564CarbamazepineAn anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia.
DB01220RifaximinA rifamycin-based non-systemic antibiotic used for the treatment of gastrointestinal bacterial infections, such as traveler's diarrhea and irritable bowel syndrome, and reduction of overt hepatic encephalopathy recurrence in adults.
DB00635PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
DB06119CenobamateA small molecule drug indicated to treat partial onset seizures in adults.
DB01222BudesonideA corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis.
DB00959MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
DrugDrug NameTargetType
DB01045RifampicinDNA-directed RNA polymerase subunit betatarget
DB01045RifampicinNuclear receptor subfamily 1 group I member 2target
DB01045RifampicinCytochrome P450 3A4enzyme
DB01045RifampicinCytochrome P450 1A2enzyme
DB01045RifampicinCytochrome P450 2C8enzyme
DB01045RifampicinUDP-glucuronosyltransferase 1-1enzyme
DB01045RifampicinCytochrome P450 2C9enzyme
DB01045RifampicinCytochrome P450 2B6enzyme
DB01045RifampicinCytochrome P450 2C19enzyme
DB01045RifampicinCanalicular multispecific organic anion transporter 2transporter
DB01045RifampicinMultidrug resistance-associated protein 5transporter
DB01045RifampicinP-glycoprotein 1transporter
DB01045RifampicinCanalicular multispecific organic anion transporter 1transporter
DB01045RifampicinSolute carrier organic anion transporter family member 2B1transporter
DB01045RifampicinBile salt export pumptransporter
DB01045RifampicinMultidrug resistance-associated protein 1transporter
DB01045RifampicinSolute carrier organic anion transporter family member 1A2transporter
DB01045RifampicinSolute carrier organic anion transporter family member 1B3transporter
DB01045RifampicinSolute carrier family 22 member 7transporter
DB01045RifampicinSolute carrier organic anion transporter family member 1B1transporter
DB01045RifampicinCytochrome P450 2A6enzyme
DB01045RifampicinCytochrome P450 2E1enzyme
DB01045RifampicinCytochrome P450 3A43enzyme
DB01045RifampicinCytochrome P450 3A7enzyme
DB01045RifampicinSolute carrier family 22 member 6transporter
DB01045RifampicinSolute carrier family 22 member 8transporter
DB01045RifampicinUDP-glucuronosyltransferase 1-9enzyme
DB01045RifampicinCytochrome P450 3A5enzyme
DB01045RifampicinSerum albumincarrier
DB01045Rifampicinalpha1-acid glycoproteincarrier
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB00418SecobarbitalCytochrome P450 2C8enzyme
DB00418SecobarbitalCytochrome P450 2C9enzyme
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB00418SecobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB00418SecobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB00418SecobarbitalGlutamate receptor 2target
DB00418SecobarbitalGlutamate receptor ionotropic, kainate 2target
DB00418SecobarbitalCytochrome P450 1A2enzyme
DB00418SecobarbitalNMDA receptortarget
DB00418SecobarbitalCytochrome P450 2C19enzyme
DB14568IvosidenibIsocitrate dehydrogenase [NADP] cytoplasmictarget
DB14568IvosidenibCytochrome P450 3A4enzyme
DB14568IvosidenibCytochrome P450 2B6enzyme
DB14568IvosidenibCytochrome P450 2C9enzyme
DB14568IvosidenibCytochrome P450 2C8enzyme
DB14568IvosidenibSolute carrier family 22 member 8transporter
DB14568IvosidenibP-glycoprotein 1transporter
DB00741HydrocortisoneAnnexin A1target
DB00741HydrocortisoneGlucocorticoid receptortarget
DB00741HydrocortisoneSex hormone-binding globulincarrier
DB00741HydrocortisoneCytochrome P450 3A4enzyme
DB00741HydrocortisoneCytochrome P450 3A5enzyme
DB00741HydrocortisoneCytochrome P450 3A7enzyme
DB00741HydrocortisoneP-glycoprotein 1transporter
DB00741HydrocortisoneSolute carrier organic anion transporter family member 1A2transporter
DB00741HydrocortisoneCytochrome P450 11B1, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 11B2, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 2C8enzyme
DB00741HydrocortisoneCorticosteroid-binding globulincarrier
DB00741HydrocortisoneSolute carrier family 22 member 8transporter
DB00741Hydrocortisone3-oxo-5-beta-steroid 4-dehydrogenaseenzyme
DB00741Hydrocortisone3-oxo-5-alpha-steroid 4-dehydrogenase 2enzyme
DB00741HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DB00741HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB00741HydrocortisoneCytochrome P450 2A6enzyme
DB00741HydrocortisoneCytochrome P450 1B1enzyme
DB00741HydrocortisoneCytochrome P450 2B6enzyme
DB00741HydrocortisoneCytochrome P450 2C9enzyme
DB00741HydrocortisoneCytochrome P450 2C19enzyme
DB14538Hydrocortisone aceponateAnnexin A1target
DB14538Hydrocortisone aceponateGlucocorticoid receptortarget
DB14538Hydrocortisone aceponateSex hormone-binding globulincarrier
DB14538Hydrocortisone aceponateCytochrome P450 3A4enzyme
DB14538Hydrocortisone aceponateCytochrome P450 3A5enzyme
DB14538Hydrocortisone aceponateCytochrome P450 3A7enzyme
DB14538Hydrocortisone aceponateP-glycoprotein 1transporter
DB14538Hydrocortisone aceponateSolute carrier organic anion transporter family member 1A2transporter
DB14538Hydrocortisone aceponateATP-binding cassette sub-family G member 2transporter
DB14538Hydrocortisone aceponateCytochrome P450 2C8enzyme
DB14538Hydrocortisone aceponateCorticosteroid-binding globulincarrier
DB14538Hydrocortisone aceponateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14538Hydrocortisone aceponate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14538Hydrocortisone aceponateSolute carrier family 22 member 8transporter
DB14539Hydrocortisone acetateAnnexin A1target
DB14539Hydrocortisone acetateGlucocorticoid receptortarget
DB14539Hydrocortisone acetateSex hormone-binding globulincarrier
DB14539Hydrocortisone acetateCytochrome P450 3A4enzyme
DB14539Hydrocortisone acetateCytochrome P450 3A5enzyme
DB14539Hydrocortisone acetateCytochrome P450 3A7enzyme
DB14539Hydrocortisone acetateP-glycoprotein 1transporter
DB14539Hydrocortisone acetateSolute carrier organic anion transporter family member 1A2transporter
DB14539Hydrocortisone acetateATP-binding cassette sub-family G member 2transporter
DB14539Hydrocortisone acetateCytochrome P450 11B1, mitochondrialenzyme
DB14539Hydrocortisone acetateCytochrome P450 11B2, mitochondrialenzyme
DB14539Hydrocortisone acetateCytochrome P450 2C8enzyme
DB14539Hydrocortisone acetateCorticosteroid-binding globulincarrier
DB14539Hydrocortisone acetateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14539Hydrocortisone acetate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14539Hydrocortisone acetateSolute carrier family 22 member 8transporter
DB14540Hydrocortisone butyrateAnnexin A1target
DB14540Hydrocortisone butyrateGlucocorticoid receptortarget
DB14540Hydrocortisone butyrateSex hormone-binding globulincarrier
DB14540Hydrocortisone butyrateCytochrome P450 3A4enzyme
DB14540Hydrocortisone butyrateCytochrome P450 3A5enzyme
DB14540Hydrocortisone butyrateCytochrome P450 3A7enzyme
DB14540Hydrocortisone butyrateP-glycoprotein 1transporter
DB14540Hydrocortisone butyrateSolute carrier organic anion transporter family member 1A2transporter
DB14540Hydrocortisone butyrateATP-binding cassette sub-family G member 2transporter
DB14540Hydrocortisone butyrateCytochrome P450 11B1, mitochondrialenzyme
DB14540Hydrocortisone butyrateCytochrome P450 11B2, mitochondrialenzyme
DB14540Hydrocortisone butyrateCytochrome P450 2C8enzyme
DB14540Hydrocortisone butyrateCorticosteroid-binding globulincarrier
DB14540Hydrocortisone butyrateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14540Hydrocortisone butyrate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14540Hydrocortisone butyrateSolute carrier family 22 member 8transporter
DB14541Hydrocortisone cypionateAnnexin A1target
DB14541Hydrocortisone cypionateGlucocorticoid receptortarget
DB14541Hydrocortisone cypionateSex hormone-binding globulincarrier
DB14541Hydrocortisone cypionateCytochrome P450 3A4enzyme
DB14541Hydrocortisone cypionateCytochrome P450 3A5enzyme
DB14541Hydrocortisone cypionateCytochrome P450 3A7enzyme
DB14541Hydrocortisone cypionateP-glycoprotein 1transporter
DB14541Hydrocortisone cypionateSolute carrier organic anion transporter family member 1A2transporter
DB14541Hydrocortisone cypionateATP-binding cassette sub-family G member 2transporter
DB14541Hydrocortisone cypionateCytochrome P450 2C8enzyme
DB14541Hydrocortisone cypionateCorticosteroid-binding globulincarrier
DB14541Hydrocortisone cypionateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14541Hydrocortisone cypionate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14541Hydrocortisone cypionateSolute carrier family 22 member 8transporter
DB14542Hydrocortisone phosphateAnnexin A1target
DB14542Hydrocortisone phosphateGlucocorticoid receptortarget
DB14542Hydrocortisone phosphateSex hormone-binding globulincarrier
DB14542Hydrocortisone phosphateCytochrome P450 3A4enzyme
DB14542Hydrocortisone phosphateCytochrome P450 3A5enzyme
DB14542Hydrocortisone phosphateCytochrome P450 3A7enzyme
DB14542Hydrocortisone phosphateP-glycoprotein 1transporter
DB14542Hydrocortisone phosphateSolute carrier organic anion transporter family member 1A2transporter
DB14542Hydrocortisone phosphateATP-binding cassette sub-family G member 2transporter
DB14542Hydrocortisone phosphateCytochrome P450 2C8enzyme
DB14542Hydrocortisone phosphateCorticosteroid-binding globulincarrier
DB14542Hydrocortisone phosphateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14542Hydrocortisone phosphate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14542Hydrocortisone phosphateSolute carrier family 22 member 8transporter
DB14543Hydrocortisone probutateAnnexin A1target
DB14543Hydrocortisone probutateGlucocorticoid receptortarget
DB14543Hydrocortisone probutateSex hormone-binding globulincarrier
DB14543Hydrocortisone probutateCytochrome P450 3A4enzyme
DB14543Hydrocortisone probutateCytochrome P450 3A5enzyme
DB14543Hydrocortisone probutateCytochrome P450 3A7enzyme
DB14543Hydrocortisone probutateP-glycoprotein 1transporter
DB14543Hydrocortisone probutateSolute carrier organic anion transporter family member 1A2transporter
DB14543Hydrocortisone probutateATP-binding cassette sub-family G member 2transporter
DB14543Hydrocortisone probutateCytochrome P450 11B1, mitochondrialenzyme
DB14543Hydrocortisone probutateCytochrome P450 11B2, mitochondrialenzyme
DB14543Hydrocortisone probutateCytochrome P450 2C8enzyme
DB14543Hydrocortisone probutateCorticosteroid-binding globulincarrier
DB14543Hydrocortisone probutateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14543Hydrocortisone probutate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14543Hydrocortisone probutateSolute carrier family 22 member 8transporter
DB14545Hydrocortisone succinateCytochrome P450 3A4enzyme
DB14545Hydrocortisone succinateCytochrome P450 2C8enzyme
DB14545Hydrocortisone succinateCytochrome P450 11B1, mitochondrialenzyme
DB14545Hydrocortisone succinateCytochrome P450 11B2, mitochondrialenzyme
DB14544Hydrocortisone valerateAnnexin A1target
DB14544Hydrocortisone valerateGlucocorticoid receptortarget
DB14544Hydrocortisone valerateSex hormone-binding globulincarrier
DB14544Hydrocortisone valerateCytochrome P450 3A4enzyme
DB14544Hydrocortisone valerateCytochrome P450 3A5enzyme
DB14544Hydrocortisone valerateCytochrome P450 3A7enzyme
DB14544Hydrocortisone valerateP-glycoprotein 1transporter
DB14544Hydrocortisone valerateSolute carrier organic anion transporter family member 1A2transporter
DB14544Hydrocortisone valerateATP-binding cassette sub-family G member 2transporter
DB14544Hydrocortisone valerateCytochrome P450 11B1, mitochondrialenzyme
DB14544Hydrocortisone valerateCytochrome P450 11B2, mitochondrialenzyme
DB14544Hydrocortisone valerateCytochrome P450 2C8enzyme
DB14544Hydrocortisone valerateCorticosteroid-binding globulincarrier
DB14544Hydrocortisone valerateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14544Hydrocortisone valerate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14544Hydrocortisone valerateSolute carrier family 22 member 8transporter
DB00615RifabutinDNA-directed RNA polymerase subunit alphatarget
DB00615RifabutinHeat shock protein HSP 90-alphatarget
DB00615RifabutinEndoplasmintarget
DB00615RifabutinCytochrome P450 3A4enzyme
DB00615RifabutinDNA-directed RNA polymerase subunit betatarget
DB00615RifabutinDNA-directed RNA polymerase subunit beta'target
DB00615RifabutinCytochrome P450 2C19enzyme
DB00615RifabutinCytochrome P450 2B6enzyme
DB00615RifabutinCytochrome P450 2C8enzyme
DB00615RifabutinCytochrome P450 2C9enzyme
DB00615RifabutinP-glycoprotein 1transporter
DB11753RifamycinCytochrome P450 3A4enzyme
DB11753RifamycinCytochrome P450 2C19enzyme
DB11753RifamycinCytochrome P450 2B6enzyme
DB11753RifamycinCytochrome P450 2C8enzyme
DB11753RifamycinCytochrome P450 2C9enzyme
DB11753RifamycinSolute carrier organic anion transporter family member 1A2transporter
DB11753RifamycinSolute carrier organic anion transporter family member 1B1transporter
DB11753RifamycinSolute carrier organic anion transporter family member 1B3transporter
DB11753RifamycinSolute carrier organic anion transporter family member 2A1transporter
DB11753RifamycinSolute carrier organic anion transporter family member 2B1transporter
DB11753RifamycinSerum albumincarrier
DB11753RifamycinDNA-directed RNA polymerase subunit betatarget
DB11753RifamycinDNA-directed RNA polymerase subunit alphatarget
DB11753RifamycinDNA-directed RNA polymerase subunit beta'target
DB11753RifamycinMultidrug and toxin extrusion protein 1transporter
DB11753RifamycinCytochrome P450 1A2enzyme
DB11753RifamycinP-glycoprotein 1transporter
DB01201RifapentineDNA-directed RNA polymerase subunit beta'target
DB01201RifapentineCytochrome P450 2C8enzyme
DB01201RifapentineCytochrome P450 2C9enzyme
DB01201RifapentineCytochrome P450 3A4enzyme
DB01201RifapentineCytochrome P450 2C19enzyme
DB01201RifapentineCytochrome P450 2B6enzyme
DB01201RifapentineCytochrome P450 3A Subfamilyenzyme
DB00400GriseofulvinTubulin beta chaintarget
DB00400GriseofulvinTubulin alpha chaintarget
DB00400GriseofulvinKeratin, type I cytoskeletal 12target
DB00400GriseofulvinCytochrome P450 1A2enzyme
DB00400GriseofulvinCytochrome P450 3A4enzyme
DB00503RitonavirHuman immunodeficiency virus type 1 proteasetarget
DB00503RitonavirCytochrome P450 2D6enzyme
DB00503RitonavirCytochrome P450 2C9enzyme
DB00503RitonavirCytochrome P450 2C19enzyme
DB00503RitonavirCytochrome P450 2B6enzyme
DB00503RitonavirCytochrome P450 2C8enzyme
DB00503RitonavirP-glycoprotein 1transporter
DB00503RitonavirMultidrug resistance-associated protein 1transporter
DB00503RitonavirCanalicular multispecific organic anion transporter 1transporter
DB00503RitonavirSolute carrier organic anion transporter family member 1A2transporter
DB00503RitonavirATP-binding cassette sub-family G member 2transporter
DB00503RitonavirSolute carrier organic anion transporter family member 1B1transporter
DB00503RitonavirCytochrome P450 1A2enzyme
DB00503RitonavirCytochrome P450 2E1enzyme
DB00503RitonavirNuclear receptor subfamily 1 group I member 2target
DB00503RitonavirSerum albumincarrier
DB00503RitonavirCytochrome P450 3A4enzyme
DB00503RitonavirCytochrome P450 3A5enzyme
DB00503RitonavirCytochrome P450 3A7enzyme
DB00503RitonavirCytochrome P450 3A43enzyme
DB00503RitonavirUDP-glucuronosyltransferase 1-1enzyme
DB00503RitonavirSolute carrier organic anion transporter family member 2B1transporter
DB00503RitonavirBile salt export pumptransporter
DB08912DabrafenibCytochrome P450 3A4enzyme
DB08912DabrafenibCytochrome P450 2C8enzyme
DB08912DabrafenibP-glycoprotein 1transporter
DB08912DabrafenibATP-binding cassette sub-family G member 2transporter
DB08912DabrafenibSolute carrier organic anion transporter family member 1B1transporter
DB08912DabrafenibSolute carrier organic anion transporter family member 1B3transporter
DB08912DabrafenibSolute carrier family 22 member 6transporter
DB08912DabrafenibSolute carrier family 22 member 8transporter
DB08912DabrafenibSerine/threonine-protein kinase B-raftarget
DB08912DabrafenibRAF proto-oncogene serine/threonine-protein kinasetarget
DB08912DabrafenibSerine/threonine-protein kinase SIK1target
DB08912DabrafenibSerine/threonine-protein kinase Nek11target
DB08912DabrafenibLIM domain kinase 1target
DB08912DabrafenibCytochrome P450 2B6enzyme
DB08912DabrafenibCytochrome P450 2C9enzyme
DB01241GemfibrozilPeroxisome proliferator-activated receptor alphatarget
DB01241GemfibrozilCytochrome P450 2C9enzyme
DB01241GemfibrozilCytochrome P450 2C8enzyme
DB01241GemfibrozilCytochrome P450 1A2enzyme
DB01241GemfibrozilCytochrome P450 2C19enzyme
DB01241GemfibrozilUDP-glucuronosyltransferase 1-1enzyme
DB01241GemfibrozilCytochrome P450 3A4enzyme
DB01241GemfibrozilUDP-glucuronosyltransferase 1-3enzyme
DB01241GemfibrozilSolute carrier organic anion transporter family member 1B1target
DB01241GemfibrozilUDP-glucuronosyltransferase 2B7enzyme
DB01241GemfibrozilUDP-glucuronosyltransferase 1-9enzyme
DB01241GemfibrozilUDP-glucuronosyltransferase 2B4enzyme
DB01241GemfibrozilUDP-glucuronosyltransferase 2B17enzyme
DB01241GemfibrozilSerum albumincarrier
DB01241GemfibrozilSolute carrier family 22 member 8target
DB01241GemfibrozilSolute carrier organic anion transporter family member 2B1target
DB01241GemfibrozilSolute carrier organic anion transporter family member 1B3target
DB01181IfosfamideCytochrome P450 2B6enzyme
DB01181IfosfamideDNAtarget
DB01181IfosfamideCytochrome P450 3A4enzyme
DB01181IfosfamideCytochrome P450 3A5enzyme
DB01181IfosfamideCytochrome P450 2C9enzyme
DB01181IfosfamideCytochrome P450 2C8enzyme
DB01181IfosfamideCytochrome P450 2A6enzyme
DB01181IfosfamideCytochrome P450 2C19enzyme
DB01181IfosfamideCytochrome P450 2C18enzyme
DB01181IfosfamideProstaglandin G/H synthase 1enzyme
DB01181IfosfamideNuclear receptor subfamily 1 group I member 2target
DB04868NilotinibTyrosine-protein kinase ABL1target
DB04868NilotinibMast/stem cell growth factor receptor Kittarget
DB04868NilotinibCytochrome P450 2D6enzyme
DB04868NilotinibCytochrome P450 2C8enzyme
DB04868NilotinibCytochrome P450 2C9enzyme
DB04868NilotinibCytochrome P450 3A4enzyme
DB04868NilotinibP-glycoprotein 1transporter
DB04868NilotinibATP-binding cassette sub-family G member 2transporter
DB04868NilotinibUDP-glucuronosyltransferase 1-1transporter
DB04868NilotinibCytochrome P450 2B6enzyme
DB04868NilotinibSolute carrier organic anion transporter family member 1B1transporter
DB00531CyclophosphamideDNAtarget
DB00531CyclophosphamideCytochrome P450 2B6enzyme
DB00531CyclophosphamideCytochrome P450 2C9enzyme
DB00531CyclophosphamideCytochrome P450 3A4enzyme
DB00531CyclophosphamideCytochrome P450 2C19enzyme
DB00531CyclophosphamideCytochrome P450 2A6enzyme
DB00531CyclophosphamideCytochrome P450 2C18enzyme
DB00531CyclophosphamideCytochrome P450 2C8enzyme
DB00531CyclophosphamideCytochrome P450 3A5enzyme
DB00531CyclophosphamideNuclear receptor subfamily 1 group I member 2target
DB01234DexamethasoneGlucocorticoid receptortarget
DB01234DexamethasoneAnnexin A1target
DB01234DexamethasoneNitric oxide synthase, inducibletarget
DB01234DexamethasoneNuclear receptor subfamily 0 group B member 1target
DB01234DexamethasoneCytochrome P450 3A4enzyme
DB01234DexamethasoneCytochrome P450 3A5enzyme
DB01234DexamethasoneCytochrome P450 3A7enzyme
DB01234DexamethasoneBile salt export pumptransporter
DB01234DexamethasoneP-glycoprotein 1transporter
DB01234DexamethasoneCanalicular multispecific organic anion transporter 1transporter
DB01234DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DB01234DexamethasoneATP-binding cassette sub-family G member 2transporter
DB01234DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB01234DexamethasoneCytochrome P450 1A1enzyme
DB01234DexamethasoneCytochrome P450 2A6enzyme
DB01234DexamethasoneCytochrome P450 2B6enzyme
DB01234DexamethasoneCytochrome P450 2C19enzyme
DB01234DexamethasoneCytochrome P450 2C8enzyme
DB01234DexamethasoneCytochrome P450 2E1enzyme
DB01234DexamethasoneCytochrome P450 3A43enzyme
DB01234DexamethasoneCytochrome P450 4A11enzyme
DB01234DexamethasoneNuclear receptor subfamily 1 group I member 2target
DB01234DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DB01234DexamethasoneSerum albumincarrier
DB01234DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DB01234DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB01234DexamethasoneSolute carrier family 22 member 8transporter
DB01032ProbenecidSolute carrier family 22 member 8target
DB01032ProbenecidSolute carrier family 22 member 11target
DB01032ProbenecidSerum albumincarrier
DB01032ProbenecidSolute carrier family 22 member 2transporter
DB01032ProbenecidSolute carrier family 22 member 1transporter
DB01032ProbenecidCanalicular multispecific organic anion transporter 2transporter
DB01032ProbenecidMultidrug resistance-associated protein 4transporter
DB01032ProbenecidMultidrug resistance-associated protein 5transporter
DB01032ProbenecidMonocarboxylate transporter 2transporter
DB01032ProbenecidSolute carrier family 22 member 5transporter
DB01032ProbenecidMultidrug resistance-associated protein 6transporter
DB01032ProbenecidMultidrug resistance-associated protein 1transporter
DB01032ProbenecidSolute carrier organic anion transporter family member 1A2transporter
DB01032ProbenecidMonocarboxylate transporter 1transporter
DB01032ProbenecidSodium/bile acid cotransportertransporter
DB01032ProbenecidSolute carrier family 22 member 6transporter
DB01032ProbenecidSolute carrier family 22 member 10transporter
DB01032ProbenecidSolute carrier family 22 member 8transporter
DB01032ProbenecidCanalicular multispecific organic anion transporter 1transporter
DB01032ProbenecidATP-binding cassette sub-family C member 11transporter
DB01032ProbenecidSolute carrier family 22 member 11transporter
DB01032ProbenecidSolute carrier organic anion transporter family member 1C1transporter
DB01032ProbenecidSolute carrier family 22 member 7transporter
DB01032ProbenecidSolute carrier family 22 member 6target
DB01032ProbenecidPannexin-1target
DB01032ProbenecidCytochrome P450 2C8enzyme
DB01032ProbenecidCytochrome P450 3A4enzyme
DB01032ProbenecidSolute carrier family 22 member 12transporter
DB01032ProbenecidSolute carrier family 2, facilitated glucose transporter member 9transporter
DB01032ProbenecidTaste receptor type 2 member 16target
DB01032ProbenecidUDP-glucuronosyltransferase 1-1enzyme
DB01032ProbenecidCytochrome P450 2C9enzyme
DB09280LumacaftorCytochrome P450 2B6enzyme
DB09280LumacaftorCytochrome P450 2C8enzyme
DB09280LumacaftorCytochrome P450 2C9enzyme
DB09280LumacaftorCytochrome P450 2C19enzyme
DB09280LumacaftorSerum albumincarrier
DB09280LumacaftorCystic fibrosis transmembrane conductance regulatortarget
DB09280LumacaftorCytochrome P450 3A4enzyme
DB09280LumacaftorP-glycoprotein 1transporter
DB06595MidostaurinProtein kinase C alpha typetarget
DB06595MidostaurinVascular endothelial growth factor receptor 2target
DB06595MidostaurinMast/stem cell growth factor receptor Kittarget
DB06595MidostaurinPlatelet-derived growth factor receptor alphatarget
DB06595MidostaurinPlatelet-derived growth factor receptor betatarget
DB06595MidostaurinReceptor-type tyrosine-protein kinase FLT3target
DB06595MidostaurinCytochrome P450 3A Subfamilyenzyme
DB06595MidostaurinCytochrome P450 1A2enzyme
DB06595MidostaurinCytochrome P450 2B6enzyme
DB06595MidostaurinCytochrome P450 2C8enzyme
DB06595MidostaurinCytochrome P450 2C9enzyme
DB06595MidostaurinCytochrome P450 2C19enzyme
DB06595MidostaurinCytochrome P450 2D6enzyme
DB06595MidostaurinCytochrome P450 2E1enzyme
DB06595MidostaurinCytochrome P450 3A4enzyme
DB06595MidostaurinCytochrome P450 3A5enzyme
DB06595MidostaurinCytochrome P450 3A7enzyme
DB06595MidostaurinCytochrome P450 3A43enzyme
DB11633IsavuconazoleCytochrome P450 3A4enzyme
DB11633IsavuconazoleCytochrome P450 3A5enzyme
DB11633IsavuconazoleCytochrome P450 2C8enzyme
DB11633IsavuconazoleCytochrome P450 2C9enzyme
DB11633IsavuconazoleCytochrome P450 2C19enzyme
DB11633IsavuconazoleCytochrome P450 2D6enzyme
DB11633IsavuconazoleCytochrome P450 2B6enzyme
DB11633IsavuconazoleUDP-glucuronosyltransferase 1-9enzyme
DB11633IsavuconazoleUDP-glucuronosyltransferase 1-8enzyme
DB11633IsavuconazoleP-glycoprotein 1transporter
DB11633IsavuconazoleATP-binding cassette sub-family G member 2transporter
DB11633IsavuconazoleSolute carrier family 22 member 2transporter
DB11633IsavuconazoleLanosterol 14-alpha demethylasetarget
DB11633IsavuconazolePotassium voltage-gated channel subfamily H member 2target
DB11633IsavuconazoleVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB11633IsavuconazoleG protein-activated inward rectifier potassium channel 2target
DB11633IsavuconazoleG protein-activated inward rectifier potassium channel 3target
DB11633IsavuconazoleATP-sensitive inward rectifier potassium channel 11target
DB11633IsavuconazolePotassium voltage-gated channel subfamily A member 5target
DB11633IsavuconazolePotassium voltage-gated channel subfamily D member 3target
DB11633IsavuconazolePotassium voltage-gated channel subfamily KQT member 1target
DB11633IsavuconazoleSodium channel protein type 5 subunit alphatarget
DB00252PhenytoinSodium channel protein type 5 subunit alphatarget
DB00252PhenytoinSodium channel protein type 1 subunit alphatarget
DB00252PhenytoinCytochrome P450 2C8enzyme
DB00252PhenytoinCytochrome P450 2C19enzyme
DB00252PhenytoinCytochrome P450 2C9enzyme
DB00252PhenytoinCytochrome P450 2B6enzyme
DB00252PhenytoinCytochrome P450 3A5enzyme
DB00252PhenytoinSerum albumincarrier
DB00252PhenytoinCytochrome P450 3A4enzyme
DB00252PhenytoinSolute carrier organic anion transporter family member 1C1transporter
DB00252PhenytoinP-glycoprotein 1transporter
DB00252PhenytoinCanalicular multispecific organic anion transporter 1transporter
DB00252PhenytoinCytochrome P450 11B1, mitochondrialenzyme
DB00252PhenytoinCytochrome P450 3A7enzyme
DB00252PhenytoinNuclear receptor subfamily 1 group I member 2target
DB00252PhenytoinSodium channel subunit beta-1target
DB00252PhenytoinSodium channel protein type 3 subunit alphatarget
DB00252PhenytoinUDP-glucuronosyltransferase 1-1enzyme
DB00252PhenytoinUDP-glucuronosyltransferase 1-6enzyme
DB00252PhenytoinUDP-glucuronosyltransferase 1-9enzyme
DB00252PhenytoinThyroxine-binding globulincarrier
DB00252PhenytoinPotassium voltage-gated channel subfamily H member 2target
DB00252PhenytoinVoltage-dependent L-type calcium channeltarget
DB00252PhenytoinSodium channel protein type 2 subunit alphatarget
DB00252PhenytoinSodium channel protein type 8 subunit alphatarget
DB00252PhenytoinGABA-A receptor (anion channel)target
DB00252PhenytoinCytochrome P450 1A2enzyme
DB00252PhenytoinCytochrome P450 2A6enzyme
DB00252PhenytoinCytochrome P450 2D6enzyme
DB00252PhenytoinCytochrome P450 2E1enzyme
DB00252PhenytoinEpoxide hydrolase 1enzyme
DB00252PhenytoinUDP-glucuronosyltransferase 1-4enzyme
DB00252PhenytoinCatechol O-methyltransferaseenzyme
DB00252PhenytoinNAD(P)H dehydrogenase [quinone] 1enzyme
DB00252PhenytoinCytochrome P450 2C18enzyme
DB00908QuinidineSodium channel protein type 5 subunit alphatarget
DB00908QuinidineAlpha-1-acid glycoprotein 1carrier
DB00908QuinidinePotassium voltage-gated channel subfamily H member 2target
DB00908QuinidinePotassium channel subfamily K member 1target
DB00908QuinidinePotassium channel subfamily K member 6target
DB00908QuinidineCytochrome P450 1A2enzyme
DB00908QuinidineCytochrome P450 2E1enzyme
DB00908QuinidineCytochrome P450 1A1enzyme
DB00908QuinidineCytochrome P450 2D6enzyme
DB00908QuinidineCytochrome P450 3A4enzyme
DB00908QuinidineCytochrome P450 3A7enzyme
DB00908QuinidineSolute carrier family 22 member 2transporter
DB00908QuinidineSolute carrier family 22 member 1transporter
DB00908QuinidineSolute carrier family 22 member 5transporter
DB00908QuinidineP-glycoprotein 1transporter
DB00908QuinidineSolute carrier organic anion transporter family member 1A2transporter
DB00908QuinidineSolute carrier family 22 member 8transporter
DB00908QuinidineCanalicular multispecific organic anion transporter 1transporter
DB00908QuinidineSolute carrier family 22 member 4transporter
DB00908QuinidineSolute carrier organic anion transporter family member 1B1transporter
DB00908QuinidineCytochrome P450 2B6enzyme
DB00908QuinidineCytochrome P450 2C9enzyme
DB00908QuinidineAlpha-1A adrenergic receptortarget
DB00908QuinidineAlpha-1B adrenergic receptortarget
DB00908QuinidineAlpha-1D adrenergic receptortarget
DB00908QuinidineBile salt export pumptransporter
DB00908QuinidineCytochrome P450 2C8enzyme
DB01174PhenobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB01174PhenobarbitalCytochrome P450 2C19enzyme
DB01174PhenobarbitalCytochrome P450 2C9enzyme
DB01174PhenobarbitalCytochrome P450 2B6enzyme
DB01174PhenobarbitalCytochrome P450 2C8enzyme
DB01174PhenobarbitalCytochrome P450 1A2enzyme
DB01174PhenobarbitalCytochrome P450 3A4enzyme
DB01174PhenobarbitalCanalicular multispecific organic anion transporter 2transporter
DB01174PhenobarbitalBile salt export pumptransporter
DB01174PhenobarbitalP-glycoprotein 1transporter
DB01174PhenobarbitalMultidrug resistance-associated protein 1transporter
DB01174PhenobarbitalSolute carrier organic anion transporter family member 2A1transporter
DB01174PhenobarbitalCanalicular multispecific organic anion transporter 1transporter
DB01174PhenobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB01174PhenobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB01174PhenobarbitalGlutamate receptor 2target
DB01174PhenobarbitalGlutamate receptor ionotropic, kainate 2target
DB01174PhenobarbitalCytochrome P450 2A6enzyme
DB01174PhenobarbitalCytochrome P450 2E1enzyme
DB01174PhenobarbitalCytochrome P450 3A5enzyme
DB01174PhenobarbitalCytochrome P450 1A1enzyme
DB01174PhenobarbitalCytochrome P450 2C18enzyme
DB01174PhenobarbitalCytochrome P450 3A7enzyme
DB01174PhenobarbitalCytochrome P450 4B1enzyme
DB01174PhenobarbitalNMDA receptortarget
DB01174PhenobarbitalNuclear receptor subfamily 1 group I member 2target
DB01174PhenobarbitalUDP-glucuronosyltransferase 1-1enzyme
DB01174PhenobarbitalUDP-glucuronosyltransferase 2B7enzyme
DB11995AvatrombopagATP-binding cassette sub-family G member 2target
DB11995AvatrombopagCytochrome P450 2C8enzyme
DB11995AvatrombopagCytochrome P450 2C9enzyme
DB11995AvatrombopagThrombopoietin receptortarget
DB11995AvatrombopagP-glycoprotein 1transporter
DB11995AvatrombopagSolute carrier family 22 member 8target
DB00564CarbamazepineVoltage-gated sodium channel alpha subunittarget
DB00564CarbamazepineCytochrome P450 2C8enzyme
DB00564CarbamazepineCytochrome P450 2B6enzyme
DB00564CarbamazepineCytochrome P450 3A4enzyme
DB00564CarbamazepineCytochrome P450 1A2enzyme
DB00564CarbamazepineCytochrome P450 2C19enzyme
DB00564CarbamazepineCytochrome P450 2C9enzyme
DB00564CarbamazepineP-glycoprotein 1transporter
DB00564CarbamazepineCytochrome P450 3A5enzyme
DB00564CarbamazepineUDP-glucuronosyltransferase 2B7enzyme
DB00564CarbamazepineRalA-binding protein 1transporter
DB00564CarbamazepineCanalicular multispecific organic anion transporter 1transporter
DB00564CarbamazepineNeuronal acetylcholine receptor subunit alpha-4target
DB00564CarbamazepineNuclear receptor subfamily 1 group I member 2target
DB00564CarbamazepineUDP-glucuronosyltransferase 1-1enzyme
DB00564CarbamazepineUDP-glucuronosyltransferase 1-6enzyme
DB00564CarbamazepineUDP-glucuronosyltransferase 1-7enzyme
DB01220RifaximinDNA-directed RNA polymerase subunit betatarget
DB01220RifaximinNuclear receptor subfamily 1 group I member 2target
DB01220RifaximinCytochrome P450 3A4enzyme
DB01220RifaximinCytochrome P450 2C19enzyme
DB01220RifaximinCytochrome P450 2C8enzyme
DB00635PrednisoneGlucocorticoid receptortarget
DB00635PrednisoneCytochrome P450 3A4enzyme
DB00635PrednisoneP-glycoprotein 1transporter
DB00635PrednisoneSolute carrier organic anion transporter family member 1A2transporter
DB00635PrednisoneCytochrome P450 2C19enzyme
DB00635PrednisoneSerum albumincarrier
DB00635PrednisoneCytochrome P450 3A5enzyme
DB00635PrednisoneCorticosteroid-binding globulincarrier
DB00635PrednisoneCytochrome P450 3A Subfamilyenzyme
DB00635PrednisoneCytochrome P450 2A6enzyme
DB00635PrednisoneCytochrome P450 1B1enzyme
DB00635PrednisoneCytochrome P450 2B6enzyme
DB00635PrednisoneCytochrome P450 2C8enzyme
DB00635PrednisoneCytochrome P450 2C9enzyme
DB00635PrednisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB06119CenobamateUDP-glucuronosyltransferase 2B7enzyme
DB06119CenobamateUDP-glucuronosyltransferase 2B4enzyme
DB06119CenobamateCytochrome P450 2E1enzyme
DB06119CenobamateCytochrome P450 2A6enzyme
DB06119CenobamateCytochrome P450 2B6enzyme
DB06119CenobamateCytochrome P450 2C19enzyme
DB06119CenobamateCytochrome P450 3A4enzyme
DB06119CenobamateCytochrome P450 3A5enzyme
DB06119CenobamateSerum albumincarrier
DB06119CenobamateCytochrome P450 2C8enzyme
DB01222BudesonideGlucocorticoid receptortarget
DB01222BudesonideCytochrome P450 3A4enzyme
DB01222BudesonideCytochrome P450 3A5enzyme
DB01222BudesonideBile salt export pumptransporter
DB01222BudesonideP-glycoprotein 1transporter
DB01222BudesonideAnnexin A1target
DB01222BudesonideCytochrome P450 3A Subfamilyenzyme
DB01222BudesonideCytochrome P450 2A6enzyme
DB01222BudesonideCytochrome P450 1B1enzyme
DB01222BudesonideCytochrome P450 2B6enzyme
DB01222BudesonideCytochrome P450 2C8enzyme
DB01222BudesonideCytochrome P450 2C9enzyme
DB01222BudesonideCytochrome P450 2C19enzyme
DB01222BudesonideCorticosteroid-binding globulincarrier
DB01222BudesonideSolute carrier organic anion transporter family member 1A2transporter
DB01222BudesonideSolute carrier family 22 member 8transporter
DB01222BudesonideSerum albumincarrier
DB00959MethylprednisoloneGlucocorticoid receptortarget
DB00959MethylprednisoloneCytochrome P450 3A4enzyme
DB00959MethylprednisoloneP-glycoprotein 1transporter
DB00959MethylprednisoloneCytochrome P450 3A Subfamilyenzyme
DB00959MethylprednisoloneCytochrome P450 2A6enzyme
DB00959MethylprednisoloneCytochrome P450 1B1enzyme
DB00959MethylprednisoloneCytochrome P450 2B6enzyme
DB00959MethylprednisoloneCytochrome P450 2C8enzyme
DB00959MethylprednisoloneCytochrome P450 2C9enzyme
DB00959MethylprednisoloneCytochrome P450 2C19enzyme
DB00959MethylprednisoloneAnnexin A1target
DB00959Methylprednisolone20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)enzyme
DB00959Methylprednisolone11beta-hydroxysteroid dehydrogenaseenzyme
DB00959MethylprednisoloneSerum albumincarrier