Showing BioInteractions for Moxisylyte (DB09205)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.

Target Mediated Interactions 1
Enzyme Mediated Interactions 2

	Interacting Group	Interacting Drugs
	Moxisylyte is a Alpha adrenergic receptor antagonist
1	Alpha adrenergic receptor agonists	Amphetamine, Aranidipine, Dihydroergocornine, Dihydroergocristine, DL-Methylephedrine, Ergoloid mesylate, Indigotindisulfonic acid, Mephentermine
2	Alpha adrenergic receptor antagonists	Dihydroergocornine, Dihydroergocristine, Ergoloid mesylate, Promethazine, Ropinirole
3	Alpha adrenergic receptor inhibitors	Dextroamphetamine
4	Alpha adrenergic receptor inducers	Dextroamphetamine

	Interacting Group	Interacting Drugs
	Moxisylyte is a Cholinesterase substrate
1	Cholinesterase inhibitors	Ambenonium, Aprotinin, Bambuterol, Betaine, Capsaicin, Chlorpromazine, Cinchocaine, Cisplatin, Decamethonium, Demecarium, Diethylcarbamazine, Echothiophate, Edrophonium, Galantamine, Hexafluronium, Isoflurophate, Ketamine, Malathion, Mechlorethamine, Mefloquine, Methylphosphinic Acid, Neostigmine, Nizatidine, Pancuronium, Pegvisomant, Perindopril, Phenserine, Pipecuronium, Procainamide, Procaine, Profenamine, Ramipril, Regramostim, Rivastigmine, Sulpiride, Tacrine, Terbutaline, Thiotepa, Tretamine, Triflupromazine
2	Cholinesterase substrates	Aclidinium, Bambuterol, Benzonatate, Butamben, Butyrylthiocholine, Chloroprocaine, Clevidipine, Cocaine, Cyclopentolate, Dipivefrin, Doxacurium, Ephedrine, Irinotecan, Mirabegron, Oxybuprocaine, Procaine, Propacetamol, Sar9, Met (O2)11-Substance P, Succinylcholine, Trimethaphan, Tubocurarine
3	Cholinesterase ligands	Butyric Acid, Ethyl dihydrogen phosphate, Phosphorylisopropane
4	Cholinesterase antagonists	Pyridostigmine
5	Cholinesterase activators	Pralidoxime
6	Cholinesterase inducers	Chlorphenesin, Donepezil, Pentagastrin, Triamcinolone

	Interacting Group	Interacting Drugs
	Moxisylyte is a Cytochrome P450 3A Subfamily substrate
1	Cytochrome P450 3A Subfamily inhibitors	Crizotinib, Diacerein, Fluvoxamine, Glecaprevir, Istradefylline, Lemborexant, Lonafarnib, Lopinavir, Lorlatinib, Midostaurin, Nefazodone, Olanzapine, Phenelzine, Pibrentasvir, Remoxipride, Rhein, Risdiplam, Selpercatinib
2	Cytochrome P450 3A Subfamily substrates	Acalabrutinib, Ambroxol acefyllinate, Budesonide, Dolutegravir, Elagolix, Ethosuximide, Foretinib, Glecaprevir, Lonafarnib, Lorlatinib, Loxoprofen, Mebendazole, Methylprednisolone, Midostaurin, Mirodenafil, Naldemedine, Omega-3-carboxylic acids, Relugolix, Tazemetostat, Thiopental, Tucatinib, Zanubrutinib
3	Cytochrome P450 3A Subfamily inducers	Brigatinib, Budesonide, Lemborexant, Methylprednisolone, Midostaurin, Myrrh, Prednisolone phosphate, Prednisone, Relugolix, Rifapentine