Hospital-acquired bacterial pneumonia

Also known as: Nosocomial Pneumonia (NP) / Nosocomial penumonia / Hospital Acquired Pneumonia (HAP) / Nosocomial pneumonia / Hospital acquired pneumonia / Pneumonia / Pneumonia NOS / Pulmonitis

DrugDrug NameDrug Description
DB00479AmikacinAn aminoglycoside used to treat infections caused by more resistant strains of Gram negative bacteria and some Gram positive bacteria.
DB04918CeftobiproleA cephalosporin antibiotic used to treat both community and hospital-acquired pneumonia caused by susceptible bacteria.
DB00537CiprofloxacinA second generation fluoroquinolone used to treat various susceptible bacterial infections.
DB01137LevofloxacinA fluoroquinolone used to treat infections including the upper respiratory tract, skin and skin structure, urinary tract, as well as pneumonia, chronic bacterial prostatitis, post exposure treatment of inhaled anthrax, and the plague.
DB00601LinezolidAn oxazolidinone antibiotic used to treat susceptible strains of multidrug resistant bacterial infections.
DB09324SulbactamAn beta-lactamase inhibitor antibiotic combined with other antibiotics to treat a variety of susceptible bacterial infections.
DB06402TelavancinAn antibacterial agent used in the treatment of complicated skin and skin structure infections and types of hospital-acquired bacterial pneumonia.
DrugDrug NameTargetType
DB00479Amikacin30S ribosomal protein S12target
DB04918CeftobiproleMecAtarget
DB04918CeftobiprolePenicillin-binding protein 2xtarget
DB04918CeftobiprolePeptidoglycan synthase FtsItarget
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 2-alphatarget
DB00537CiprofloxacinCytochrome P450 1A2enzyme
DB00537CiprofloxacinCytochrome P450 3A4enzyme
DB00537CiprofloxacinCytochrome P450 3A5enzyme
DB00537CiprofloxacinCytochrome P450 3A7enzyme
DB00537CiprofloxacinP-glycoprotein 1transporter
DB00537CiprofloxacinPotassium voltage-gated channel subfamily H member 2target
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Btarget
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinMultidrug resistance protein MdtKtarget
DB00537CiprofloxacinGyrase Atarget
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinMultidrug and toxin extrusion protein 1transporter
DB00537CiprofloxacinMultidrug and toxin extrusion protein 2transporter
DB00537CiprofloxacinSerum albumincarrier
DB01137LevofloxacinDNA gyrase subunit Atarget
DB01137LevofloxacinDNA topoisomerase 4 subunit Atarget
DB01137LevofloxacinDNA topoisomerase 2-alphatarget
DB01137LevofloxacinCytochrome P450 1A2enzyme
DB01137LevofloxacinSolute carrier family 22 member 2transporter
DB01137LevofloxacinP-glycoprotein 1transporter
DB01137LevofloxacinSolute carrier family 22 member 4transporter
DB01137LevofloxacinSolute carrier family 22 member 6transporter
DB01137LevofloxacinCytochrome P450 3A4enzyme
DB01137LevofloxacinMultidrug and toxin extrusion protein 1transporter
DB01137LevofloxacinMultidrug and toxin extrusion protein 2transporter
DB01137LevofloxacinCytochrome P450 2C9enzyme
DB00601Linezolid23S ribosomal RNAtarget
DB00601LinezolidAmine oxidase [flavin-containing] Aenzyme
DB00601LinezolidAmine oxidase [flavin-containing] Benzyme
DB09324SulbactamBeta-lactamasetarget
DrugDrug NamePhaseStatusCount
DB08816Ticagrelor1Completed1
DB09060Avibactam3Completed1
DB14879Cefiderocol3Active Not Recruiting1
DB14879Cefiderocol3Completed1
DB00438Ceftazidime3Completed1
DB09050Ceftolozane3Completed1
DB01111Colistimethate3Completed1
DB00803Colistin3Completed1
DB00803Colistin3Recruiting1
DB01598Imipenem3Completed1
DB01598Imipenem3Recruiting1
DB01137Levofloxacin3Completed1
DB00601Linezolid3Completed1
DB00601Linezolid3Recruiting1
DB00760Meropenem3Completed3
DB00760Meropenem3Withdrawn1
DB00319Piperacillin3Withdrawn1
DB01045Rifampicin3Completed1
DB09324Sulbactam3Recruiting1
DB01606Tazobactam3Completed1
DB01606Tazobactam3Withdrawn1
DB12107Vaborbactam3Withdrawn1
DB00878Chlorhexidine4Completed1
DB00601Linezolid4Completed1
DB13831Potassium permanganate4Completed1
DB00512Vancomycin4Completed1
DB00802AlfentanilNot AvailableRecruiting1
DB00479AmikacinNot AvailableRecruiting1
DB00513Aminocaproic acidNot AvailableRecruiting1
DB00559BosentanNot AvailableRecruiting1
DB01413CefepimeNot AvailableRecruiting1
DB00369CidofovirNot AvailableRecruiting1
DB00537CiprofloxacinNot AvailableRecruiting1
DB00363ClozapineNot AvailableRecruiting1
DB00828FosfomycinNot AvailableRecruiting1
DB00502HaloperidolNot AvailableRecruiting1
DB00598LabetalolNot AvailableRecruiting1
DB08815LurasidoneNot AvailableRecruiting1
DB00959MethylprednisoloneNot AvailableRecruiting1
DB01618MolindoneNot AvailableRecruiting1
DB00607NafcillinNot AvailableRecruiting1
DB01115NifedipineNot AvailableRecruiting1
DB00497OxycodoneNot AvailableRecruiting1
DB00312PentobarbitalNot AvailableRecruiting1
DB00319PiperacillinNot AvailableRecruiting1
DB00728RocuroniumNot AvailableRecruiting1
DB00658SevelamerNot AvailableRecruiting1
DB00421SpironolactoneNot AvailableRecruiting1
DB01606TazobactamNot AvailableRecruiting1
DB00684TobramycinNot AvailableRecruiting1
DB00302Tranexamic acidNot AvailableRecruiting1
DB00512VancomycinNot AvailableRecruiting1
DB01339VecuroniumNot AvailableRecruiting1
DB00682WarfarinNot AvailableRecruiting1
DB00246ZiprasidoneNot AvailableRecruiting1
DB00425ZolpidemNot AvailableRecruiting1