Invasive Breast Carcinoma

Also known as: Invasive carcinoma of breast / Breast cancer invasive NOS

DrugDrug NameDrug Description
DB00675TamoxifenA selective estrogen receptor modulator used to treat estrogen receptor positive breast cancer, reduce the risk of invasive breast cancer following surgery, or reduce the risk of breast cancer in high risk women.
DrugDrug NameTargetType
DB00675TamoxifenEstrogen receptor alphatarget
DB00675TamoxifenEstrogen receptor betatarget
DB00675TamoxifenCytochrome P450 2C9enzyme
DB00675TamoxifenCytochrome P450 3A4enzyme
DB00675TamoxifenCytochrome P450 2D6enzyme
DB00675TamoxifenCytochrome P450 2C8enzyme
DB00675TamoxifenCytochrome P450 2B6enzyme
DB00675TamoxifenLiver carboxylesterase 1enzyme
DB00675TamoxifenCytochrome P450 3A5enzyme
DB00675TamoxifenCytochrome P450 1A1enzyme
DB00675TamoxifenCytochrome P450 1B1enzyme
DB00675TamoxifenCytochrome P450 2C19enzyme
DB00675TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00675TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00675TamoxifenCytochrome P450 3A7enzyme
DB00675TamoxifenP-glycoprotein 1transporter
DB00675TamoxifenATP-binding cassette sub-family G member 2transporter
DB00675TamoxifenCytochrome P450 19A1enzyme
DB00675TamoxifenCytochrome P450 2A6enzyme
DB00675TamoxifenCytochrome P450 2E1enzyme
DB00675TamoxifenUDP-glucuronosyltransferase 1-10enzyme
DB00675TamoxifenSulfotransferase 1A1enzyme
DB00675TamoxifenCanalicular multispecific organic anion transporter 1transporter
DB00675Tamoxifen3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerasetarget
DB00675TamoxifenProtein kinase Ctarget
DB00675TamoxifenAndrogen receptortarget
DB00675TamoxifenPotassium voltage-gated channel subfamily H member 2target
DB00675TamoxifenNuclear receptor subfamily 1 group I member 2target
DB00675TamoxifenEstrogen-related receptor gammatarget
DB00675TamoxifenSex hormone-binding globulintarget
DB00675TamoxifenBile salt export pumptransporter
DB00675TamoxifenThyroxine-binding globulincarrier
DB00675TamoxifenBile salt sulfotransferaseenzyme
DB00675TamoxifenCytochrome P450 1A2enzyme
DB00675TamoxifenUDP-glucuronosyltransferase 2B7enzyme
DB00675TamoxifenUDP-glucuronosyltransferase 2B17enzyme
DB00675TamoxifenEstrogen sulfotransferaseenzyme
DB00675TamoxifenATP-binding cassette sub-family A member 1transporter
DB00675TamoxifenMitogen-activated protein kinase 8target
DB00675TamoxifenSerum albumincarrier
DrugDrug NamePhaseStatusCount
DB01026Ketoconazole0Recruiting1
DB123169CUAB301Recruiting1
DB01217Anastrozole1Completed1
DB01217Anastrozole1Not Yet Recruiting1
DB00307Bexarotene1Recruiting1
DB11841Entinostat1Completed1
DB11841Entinostat1Recruiting1
DB00990Exemestane1Not Yet Recruiting1
DB00947Fulvestrant1Completed1
DB00947Fulvestrant1Not Yet Recruiting1
DB06186Ipilimumab1Recruiting1
DB01259Lapatinib1Completed1
DB01006Letrozole1Not Yet Recruiting1
DB09035Nivolumab1Recruiting1
DB01229Paclitaxel1Not Yet Recruiting1
DB05386Regramostim1Not Yet Recruiting1
DB11119Sodium iodide1Active Not Recruiting1
DB13896Talimogene laherparepvec1Not Yet Recruiting1
DB00675Tamoxifen1Not Yet Recruiting1
DB00072Trastuzumab1Completed1
DB00169Cholecalciferol1 / 2Withdrawn1
DB12483Copanlisib1 / 2Suspended1
DB01006Letrozole1 / 2Suspended1
DB01229Paclitaxel1 / 2Recruiting1
DB09073Palbociclib1 / 2Suspended1
DB13896Talimogene laherparepvec1 / 2Recruiting1
DB12001Abemaciclib2Not Yet Recruiting1
DB04468Afimoxifene2Not Yet Recruiting1
DB05220Alisertib2Recruiting1
DB11595Atezolizumab2Active Not Recruiting1
DB11595Atezolizumab2Recruiting1
DB11945Avelumab2Recruiting1
DB00112Bevacizumab2Recruiting1
DB11967Binimetinib2Recruiting1
DB01101Capecitabine2Terminated1
DB00958Carboplatin2Active Not Recruiting1
DB00958Carboplatin2Completed1
DB00958Carboplatin2Recruiting2
DB00531Cyclophosphamide2Completed1
DB00531Cyclophosphamide2Recruiting2
DB01262Decitabine2Recruiting1
DB01248Docetaxel2Recruiting1
DB03756Doconexent2Active Not Recruiting1
DB00997Doxorubicin2Recruiting3
DB08899Enzalutamide2Recruiting1
DB01590Everolimus2Recruiting1
DB00947Fulvestrant2Recruiting1
DB04845Ixabepilone2Active Not Recruiting1
DB01259Lapatinib2Active Not Recruiting1
DB01229Paclitaxel2Active Not Recruiting1
DB01229Paclitaxel2Recruiting6
DB01269Panitumumab2Recruiting1
DB03010Patupilone2Active Not Recruiting1
DB09037Pembrolizumab2Recruiting1
DB00641Simvastatin2Recruiting1
DB00877Sirolimus2Recruiting1
DB11760Talazoparib2Active Not Recruiting1
DB04572Thiotepa2Completed1
DB08911Trametinib2Completed1
DB00072Trastuzumab2Recruiting1
DB11969Uprosertib2Completed1
DB15113Utomilumab2Recruiting1
DB01217Anastrozole3Active Not Recruiting1
DB00112Bevacizumab3Active Not Recruiting1
DB01101Capecitabine3Recruiting1
DB00958Carboplatin3Recruiting1
DB14547Chloride ion3Recruiting1
DB00515Cisplatin3Recruiting1
DB08871Eribulin3Suspended1
DB00990Exemestane3Active Not Recruiting1
DB01006Letrozole3Active Not Recruiting2
DB01229Paclitaxel3Suspended1
DB09037Pembrolizumab3Recruiting1
DB12257Platinum3Recruiting1
DB00675Tamoxifen3Active Not Recruiting2
DB01217Anastrozole4Withdrawn1
DB00990Exemestane4Withdrawn1
DB01006Letrozole4Withdrawn1
DB00675Tamoxifen4Withdrawn1
DB00539Toremifene4Withdrawn1