Invasive Breast Carcinoma

Also known as: Invasive breast carcinoma / Invasive carcinoma of breast / Breast cancer invasive NOS

DrugDrug NameDrug Description
DB00675TamoxifenOne of the selective estrogen receptor modulators (SERM) with tissue-specific activities for the treatment and prevention of estrogen receptor positive breast cancer. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the endometrium. [PubChem]
DrugDrug NameTargetType
DB00675TamoxifenEstrogen receptor alphatarget
DB00675TamoxifenEstrogen receptor betatarget
DB00675TamoxifenCytochrome P450 2C9enzyme
DB00675TamoxifenCytochrome P450 3A4enzyme
DB00675TamoxifenCytochrome P450 2D6enzyme
DB00675TamoxifenCytochrome P450 2C8enzyme
DB00675TamoxifenCytochrome P450 2B6enzyme
DB00675TamoxifenLiver carboxylesterase 1enzyme
DB00675TamoxifenCytochrome P450 3A5enzyme
DB00675TamoxifenCytochrome P450 1A1enzyme
DB00675TamoxifenCytochrome P450 1A2enzyme
DB00675TamoxifenCytochrome P450 1B1enzyme
DB00675TamoxifenCytochrome P450 2C19enzyme
DB00675TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00675TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00675TamoxifenCytochrome P450 3A7enzyme
DB00675TamoxifenMultidrug resistance protein 1transporter
DB00675TamoxifenBile salt export pumptransporter
DB00675TamoxifenATP-binding cassette sub-family G member 2transporter
DB00675TamoxifenCytochrome P450 19A1enzyme
DB00675TamoxifenCytochrome P450 2A6enzyme
DB00675TamoxifenCytochrome P450 2E1enzyme
DB00675TamoxifenUDP-glucuronosyltransferase 1-10enzyme
DB00675TamoxifenSulfotransferase 1A1enzyme
DB00675TamoxifenCanalicular multispecific organic anion transporter 1transporter
DB00675Tamoxifen3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerasetarget
DB00675TamoxifenProtein kinase Ctarget
DB00675TamoxifenAndrogen receptortarget
DB00675TamoxifenPotassium voltage-gated channel subfamily H member 2target
DB00675TamoxifenNuclear receptor subfamily 1 group I member 2target
DB00675TamoxifenEstrogen-related receptor gammatarget
DB00675TamoxifenSex hormone-binding globulintarget
DrugDrug NamePhaseStatusCount
DB01217Anastrozole1Active Not Recruiting1
DB00307Bexarotene1Not Yet Recruiting1
DB11841Entinostat1Active Not Recruiting1
DB11841Entinostat1Recruiting1
DB00947Fulvestrant1Active Not Recruiting1
DB06186Ipilimumab1Recruiting1
DB01259Lapatinib1Active Not Recruiting1
DB09035Nivolumab1Recruiting1
DB00072Trastuzumab1Active Not Recruiting1
DB00169Cholecalciferol1 / 2Recruiting1
DB12483Copanlisib1 / 2Not Yet Recruiting1
DB01006Letrozole1 / 2Not Yet Recruiting1
DB01229Paclitaxel1 / 2Recruiting1
DB09073Palbociclib1 / 2Not Yet Recruiting1
DB13896Talimogene laherparepvec1 / 2Recruiting1
DB05220Alisertib2Recruiting1
DB11595Atezolizumab2Recruiting1
DB01101Capecitabine2Terminated1
DB00958Carboplatin2Completed1
DB00958Carboplatin2Recruiting2
DB00493Cefotaxime2Recruiting1
DB00531Cyclophosphamide2Completed1
DB00531Cyclophosphamide2Recruiting2
DB01262Decitabine2Recruiting1
DB11292Docosahexaenoate2Active Not Recruiting1
DB00997Doxorubicin2Recruiting2
DB00947Fulvestrant2Recruiting1
DB01259Lapatinib2Recruiting1
DB01229Paclitaxel2Recruiting3
DB09037Pembrolizumab2Recruiting1
DB04572Thiotepa2Completed1
DB08911Trametinib2Active Not Recruiting1
DB00072Trastuzumab2Recruiting1
DB11969Uprosertib2Active Not Recruiting1
DB01217Anastrozole3Recruiting1
DB01101Capecitabine3Recruiting1
DB00958Carboplatin3Recruiting1
DB00515Cisplatin3Recruiting1
DB00990Exemestane3Recruiting1
DB01006Letrozole3Recruiting1
DB12117Mitometh3Recruiting1
DB09037Pembrolizumab3Recruiting1
DB00675Tamoxifen3Recruiting1
DB01217Anastrozole4Not Yet Recruiting1
DB00990Exemestane4Not Yet Recruiting1
DB01006Letrozole4Not Yet Recruiting1
DB00675Tamoxifen4Not Yet Recruiting1
DB00539Toremifene4Not Yet Recruiting1