Infections, Fungal

Also known as: Fungal Infection / Fungal infections / Infection, Fungal / Mycoses / Mycosis / Fungal infection NOS / Infection fungal / Fungemia NOS / Infection mycotic / Fungal infectious disorders / Infection fungal (mycotic)

DrugDrug NameDrug Description
DB00681Amphotericin BAn antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis.
DB00520CaspofunginAn echinocandin used to treat a variety of fungal infections.
DB00196FluconazoleA triazole antifungal used to treat various fungal infections including candidiasis.
DB01099FlucytosineAn antifungal indicated only to treat severe infections throughout the body caused by susceptible strains of Candida or Cryptococcus.
DB00406Gentian violet cationAn antiseptic violet dye used to prevent various infections, including fungal and bacterial infections.
DB01167ItraconazoleAn antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis.
DB01141MicafunginAn antifungal agent used for the treatment of candidemia, acute disseminated candidiasis, and certain other invasive Candida infections, and for the prophylaxis of Candida infections during stem cell transplantation.
DB01263PosaconazoleA triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
DB00582VoriconazoleA triazole compound used to treat fungal infections.
DrugDrug NameTargetType
DB00681Amphotericin BErgosteroltarget
DB00681Amphotericin BCytochrome P450 3A4enzyme
DB00520CaspofunginSolute carrier family 22 member 1transporter
DB00520CaspofunginP-glycoprotein 1transporter
DB00520CaspofunginSolute carrier family 22 member 6transporter
DB00520CaspofunginSolute carrier organic anion transporter family member 1B1transporter
DB00520CaspofunginSolute carrier organic anion transporter family member 1B3transporter
DB00520CaspofunginCytochrome P450 3A4enzyme
DB00520Caspofungin1,3-beta-glucan synthase component FKS1target
DB00196FluconazoleCytochrome P450 3A4enzyme
DB00196FluconazoleCytochrome P450 2C9enzyme
DB00196FluconazoleCytochrome P450 2C19enzyme
DB00196FluconazoleP-glycoprotein 1transporter
DB00196FluconazoleCytochrome P450 51target
DB00196FluconazoleCytochrome P450 3A5enzyme
DB01099FlucytosineThymidylate synthasetarget
DB01099FlucytosineDNA (cytosine-5)-methyltransferase 1target
DB01099FlucytosineDNAtarget
DB00406Gentian violet cationDNAtarget
DB00406Gentian violet cationSolute carrier family 22 member 1transporter
DB01167ItraconazoleLanosterol 14-alpha demethylasetarget
DB01167ItraconazoleLanosterol 14-alpha demethylasetarget
DB01167ItraconazoleCytochrome P450 3A4enzyme
DB01167ItraconazoleCytochrome P450 3A5enzyme
DB01167ItraconazoleCytochrome P450 3A7enzyme
DB01167ItraconazoleCytochrome P450 2B6enzyme
DB01167ItraconazoleP-glycoprotein 1transporter
DB01167ItraconazoleCytochrome P450 1A1enzyme
DB01167ItraconazoleCytochrome P450 2E1enzyme
DB01167ItraconazoleSolute carrier organic anion transporter family member 2B1transporter
DB01141MicafunginArylsulfatase Aenzyme
DB01141MicafunginCatechol O-methyltransferaseenzyme
DB01141Micafungin1,3-beta-glucan synthase component FKS1target
DB01263PosaconazoleCytochrome P450 3A4enzyme
DB01263PosaconazoleP-glycoprotein 1transporter
DB01263PosaconazoleCytochrome P450 51target
DB00582VoriconazoleCytochrome P450 2C19enzyme
DB00582VoriconazoleCytochrome P450 3A4enzyme
DB00582VoriconazoleCytochrome P450 2C9enzyme
DB00582VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00582VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00582VoriconazoleCytochrome P450 3A5enzyme
DB00582VoriconazoleCytochrome P450 3A7enzyme
DB00582VoriconazoleProstaglandin G/H synthase 1enzyme
DB00582VoriconazoleCytochrome P450 51target
DB00582VoriconazoleCytochrome P450 2B6enzyme
DrugDrug NamePhaseStatusCount
DB00254Doxycycline1Completed1
DB06414Etravirine1Completed1
DB00196Fluconazole1Completed1
DB01319Fosamprenavir1Completed1
DB15183Fosmanogepix1Completed2
DB01141Micafungin1Completed2
DB01263Posaconazole1Active Not Recruiting2
DB01263Posaconazole1Completed4
DB01263Posaconazole1Terminated1
DB00503Ritonavir1Completed1
DB00582Voriconazole1Completed5
DB00520Caspofungin2Completed3
DB00520Caspofungin2Recruiting1
DB00520Caspofungin2Unknown Status1
DB00196Fluconazole2Completed1
DB01073Fludarabine2Recruiting1
DB14158Microcrystalline cellulose2Completed1
DB01263Posaconazole2Completed1
DB01263Posaconazole2Recruiting1
DB04572Thiotepa2Recruiting1
DB11678Treosulfan2Recruiting1
DB00257Clotrimazole2 / 3Recruiting1
DB01167Itraconazole2 / 3Recruiting1
DB01110Miconazole2 / 3Recruiting1
DB00681Amphotericin B3Completed2
DB00520Caspofungin3Active Not Recruiting3
DB00520Caspofungin3Completed4
DB00520Caspofungin3Recruiting1
DB00257Clotrimazole3Unknown Status1
DB00196Fluconazole3Active Not Recruiting2
DB00196Fluconazole3Recruiting1
DB01167Itraconazole3Completed1
DB01137Levofloxacin3Completed1
DB01141Micafungin3Completed2
DB14158Microcrystalline cellulose3Recruiting1
DB01263Posaconazole3Completed2
DB00582Voriconazole3Active Not Recruiting1
DB00582Voriconazole3Completed2
DB00681Amphotericin B4Completed1
DB00681Amphotericin B4Recruiting1
DB00681Amphotericin B4Terminated1
DB00362Anidulafungin4Completed1
DB00520Caspofungin4Completed1
DB01167Itraconazole4Not Yet Recruiting1
DB01263Posaconazole4Completed1
DB01263Posaconazole4Recruiting1
DB01263Posaconazole4Terminated2
DB00582Voriconazole4Completed3
DB00520CaspofunginNot AvailableNot Yet Recruiting1
DB00196FluconazoleNot AvailableRecruiting1
DB01263PosaconazoleNot AvailableCompleted1
DB01263PosaconazoleNot AvailableRecruiting1
DB00582VoriconazoleNot AvailableActive Not Recruiting1