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Identification
NameIron
Accession NumberDB01592
TypeSmall Molecule
GroupsApproved
Description

A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of iron stores may result in iron-deficiency anemia. Iron is used to build up the blood in anemia.

Structure
Thumb
Synonyms
Carbonyl iron
Eisen
Electrolytic iron
Fe
fer
Ferrum
Ferrum metallicum
Hierro
Iron powder
Iron, carbonyl
Iron, electrolytic
Iron, elemental
Iron, reduced
Reduced iron
External Identifiers Not Available
Approved Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Dexironliquid50 mgintramuscular; intravenousLuitpold Pharmaceuticals Inc1996-09-06Not applicableCanada
Ferahemesolution30 mgintravenousAmag Pharmaceuticals Inc2012-05-01Not applicableCanada
Ferrous Sulfate Ect 300mgtablet (enteric-coated)300 mgBionatal Drug Co1977-12-311999-07-14Canada
Ferrous Sulfate Tablets 300mgtablet300 mgPharmadex Laboratories Inc.1993-12-311999-08-28Canada
Infuferliquid50 mgintramuscular; intravenousSandoz Canada Incorporated1997-02-07Not applicableCanada
Venoferliquid20 mgintravenousLuitpold Pharmaceuticals Inc2001-06-05Not applicableCanada
Approved Generic Prescription ProductsNot Available
Approved Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Ascofer Cap 275mgcapsule33 mgoralDesbergers LtÉe, Division Of Technilab Inc.1974-12-311999-09-17Canada
Chelated Iron 25mg - Caplettablet25 mgoralHealth Wise Nutrition Inc.1995-12-312002-07-18Canada
Chelated Iron Supplement - Tabtablet18 mgoralAlbion Laboratories Inc.1996-09-062002-09-30Canada
Fe-chelate Tabtablet28 mgoralNutri West Products Ltd.1994-12-311997-08-05Canada
Fera Liq 16.7mg/15mlliquid16.7 mgoralInno Vite Incorporated1987-12-312007-07-31Canada
Ferinsol Dropsdrops125 mgoralMead Johnson Nutritionals1951-12-311996-09-30Canada
Ferion Tabtablet65 mgoralPharmetics (2011) Inc1981-12-312000-08-21Canada
Fero Grad Filmtabtablet (extended-release)105 mgoralAbbott Laboratories, Limited1961-12-312008-06-06Canada
Ferrous Fumarate Sct Tab 300mgtablet300 mgoralPharmetics (2011) Inc1978-12-312000-08-21Canada
Ferrous Fumarate Tab 200mgtablet200 mgoralShoppers Drug Mart Inc.1977-12-311998-08-14Canada
Ferrous Gluconatetablet35 mgoralWn Pharmaceuticals Ltd.2002-05-312007-08-07Canada
Ferrous Gluconate Tab 300mgtablet300 mgoralShoppers Drug Mart Inc.1977-12-311997-08-15Canada
Ferrous Gluconate Tab 300mgtablet300 mgoralPharmetics (2011) Inc1973-12-312000-08-21Canada
Ferrous Gluconate Tab 300mgtablet300 mgoralVita Health Products Inc1957-12-312005-07-20Canada
Ferrous Gluconate Tablet 300mgtablet300 mgoralD.C. Labs Limited1969-12-312005-07-19Canada
Ferrous Sulfate Tab 300mgtablet (enteric-coated)300 mgoralShoppers Drug Mart Inc.1980-12-311998-08-14Canada
Ferrous Sulfate Tab 300mgtablet (enteric-coated)300 mgoralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1957-12-312002-07-31Canada
Ferrous Sulfate Tab 325mg USPtablet325 mgoralPharmavite Llc1991-12-312000-08-24Canada
Ferrous Sulphatetablet35 mgoralWn Pharmaceuticals Ltd.2002-05-312007-08-07Canada
Fertinic Syr 35mg/5mlsyrup35 mgoralDesbergers LtÉe, Division Of Technilab Inc.1973-12-312000-09-06Canada
Fertinic Tab 300mgtablet300 mgoralDesbergers LtÉe, Division Of Technilab Inc.1939-12-311999-09-17Canada
Gnc Timed Release Womens Iron Fmla-src 30mgcapsule (sustained-release)30 mgoralGeneral Nutrition Canada Inc.2001-10-202005-08-05Canada
Ironcapsule40 mgoralSeroyal International Inc.1994-12-312008-10-09Canada
Iron 30mg Tabletstablet30 mgoralBioforce Canada Inc.1994-12-311997-04-14Canada
Iron 35mg Sustained Release Dietary Supplementtablet (extended-release)35 mgoralGarden State Nutritionals1998-09-222000-06-07Canada
Iron Amino Chelate Tab 37mgtablet37 mgoralPure Life International Prods Inc.1992-12-312000-07-27Canada
Iron Ascorbate Capscapsule50 mgoralFinlandia Consultants1990-12-311997-12-02Canada
Iron Cap 50mg Time Releasetablet (extended-release)50 mgoralSwiss Herbal Remedies Ltd.1981-12-311998-07-15Canada
Iron Chelate 25 mgtablet25 mgoralWn Pharmaceuticals Ltd.2002-03-132006-08-08Canada
Iron Dietary Supplementtablet35 mgoralGarden State Nutritionals1998-09-222000-06-07Canada
Iron Tabtablet18 mgoralShaklee Canada Inc1982-12-312001-04-01Canada
Kids Chewable Irontablet6 mgoralQuixtar Canada Corporation2001-06-242004-06-22Canada
Novo-ferrosulfa Ect 300mgtablet (enteric-coated)300 mgoralNovopharm Limited1966-12-311996-09-10Canada
Novo-ferrosulfa Tab 300mg(fct)tablet300 mgoralNovopharm Limited1991-12-311996-09-10Canada
Novo-fumar 200mgtablet200 mgoralNovopharm Limited1967-12-312005-08-10Canada
Scheinpharm Ferrous Fumarate - 300mgcapsule100 mgoralSchein Pharmaceutical Canada Inc.1997-05-272004-07-26Canada
Sulfate Ferreux 300mg Tabtablet (enteric-coated)60 mgoralPro Doc Limitee1982-12-312009-07-23Canada
Timed Release Iron 35mgtablet (extended-release)35 mgoralNutricorp International1999-11-302009-08-05Canada
Timed Release Iron 50mgtablet (extended-release)50 mgoralNutricorp International2003-09-302009-08-06Canada
Timed Release Iron 50mg Tabletstablet (extended-release)50 mgoralSwiss Herbal Remedies Ltd.1998-01-262008-08-15Canada
Usana Iron 28 Supplementtablet28 mgoralUsana Health Sciences Inc.1999-09-302001-07-18Canada
Unapproved/Other Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Ferrous Sulfatetablet, film coated325 mg/1oralCentral Texas Community Health Centers2014-07-01Not applicableUs
Ferrous Sulfatetablet, film coated325 mg/1oralSun Pharmaceutical Industries, Inc.2014-07-01Not applicableUs
Ferrous Sulfatetablet325 mg/1oralQualitest Pharmaceuticals2001-02-19Not applicableUs
Ferrous Sulfatetablet325 mg/1oralA S Medication Solutions2001-02-19Not applicableUs
Ferrous Sulfatetablet, film coated325 mg/1oralSun Pharmaceutical Industries, Inc.2014-07-01Not applicableUs
Ferrous Sulfatetablet325 mg/1oralA S Medication Solutions2001-02-19Not applicableUs
Ferrous Sulfatetablet325 mg/1oralRichmond Pharmaceuticals Inc.2008-11-05Not applicableUs
Ferrous Sulfatetablet325 mg/1oralState of Florida DOH Central Pharmacy2014-01-01Not applicableUs
Ferrous Sulfateelixir220 mg/5mLoralRij Pharmaceutical Corporation1999-03-16Not applicableUs
Ferrous Sulfatetablet325 mg/1oralPreferred Pharmaceuticals, Inc.2004-06-18Not applicableUs
Ferrous Sulfatetablet325 mg/1oralUnit Dose Services2001-02-19Not applicableUs
Ferrous Sulfatetablet65 mg/1oralBoca Pharmacal, LLC2010-09-14Not applicableUs
Ferrous Sulfatetablet325 mg/1oralUnit Dose Services2001-02-19Not applicableUs
Ferrous Sulfateelixir220 mg/5mLoralLLC Federal Solutions2013-08-12Not applicableUs
Iferex 150capsule150 mg/1oralNnodum Pharmaceuticals2007-10-28Not applicableUs
Iron Chewstablet, chewable15 mg/1oralMidlothian Laboratories2009-01-01Not applicableUs
Polysaccharide-ironcapsule150 mg/1oralAdvance Pharmaceutical Inc.2015-05-26Not applicableUs
International Brands
NameCompany
Ed-In-SolNot Available
Fe-40Not Available
FeosolGlaxoSmithkline
FeostatNot Available
Fer-In-SolNot Available
FeratabUpsher-Smith
FerateNot Available
FergonNot Available
FerraletNot Available
FerrettsNot Available
Ferro sanolNot Available
Ferro-CapsNot Available
Ferro-TimeNot Available
FerrousalNot Available
SiderolNot Available
SimronNot Available
Slow FeNot Available
Vitedyn-SloNot Available
YieroniaNot Available
Brand mixtures
NameLabellerIngredients
Active FeGm Pharmaceuticals, Inc.
ActyformTechnodiet S.E.N.C.
Alsimine W Vitamins A DAlsi Cie Ltee
AppedrineChattem Canada
B Stress C + Iron & ViteStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
BacminMarnel Pharmaceuticals, Inc.
Beautel Supplement De Vitamines Et MineralNobel Pharm Enr.
Bev 29 TabBeverly International Nutrition
Bioferr 90Biocomp Pharma, Inc.
Bugs Bunny Chew Multi Vit Plus IronMiles Canada Inc. Consumer Health Care Division
C-nate DHACenturion Labs, Llc
Calcium Et Magnesium Plus Vitamine D/fe/znLaboratoire Lalco Inc.
Calcium Vitamin D Iron MagLaboratoire Lalco Inc.
Chewable Multiple Vit Plus Iron for ChildrenRandle Pharmaceutical Inc.
Chewable Multiple Vitamins Plus Iron TabRandle Pharmaceutical Inc.
Chewable Multivitamins Plus IronWn Pharmaceuticals Ltd.
Chezyn TabStandard Process Inc.
Children's Chewable Multi Vit W IronShoppers Drug Mart Inc.
Children's Chewable Multi Vitamins With Iron TabletsVita Health Products Inc
Children's Chewable Multi-vitamin Complete With MineralsWn Pharmaceuticals Ltd.
Children's Chewable Multiple Vit.plus IronStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Children's Chewable Multiple Vitamins With Iron Tablets (chewable Tablets)Pharmetics (2011) Inc
Children's Vitamins W Iron ChewableVita Health Products Inc
Childrens Chewable Multiple Vitamins Plus FeKsl Pharmaceuticals
Childrens Chewable Multivitamins W IronRandle Labs Inc.
Childrens Multiple Vit and Min Chew TabCountry Health Laboratories Ltd.
Citranatal B-calmMission Pharmacal Company
Citranatal DHAMission Pharmacal Company
Citranatal Harmony 2.1Mission Pharmacal Company
Citranatal Harmony 3.0Mission Pharmacal Company
Citranatal RxMission Pharmacal Company
Concept DHAUs Pharmaceutical Corporation
Concept ObUs Pharmaceutical Corporation
Copper 3mg Plus Iron & Zinc TabSwiss Herbal Remedies Ltd.
Dexatrim TabletsChattem Canada
Dynam Ampoule Et TabletCardinaux Enrg Les Produits Naturels
EscaviteGm Pharmaceuticals, Inc.
Everyday Multiple Vitamins With IronD.C. Labs Limited
Extra-virt Plus DHAVirtus Pharmaceuticals LLC
Fe C TabBoca Pharmacal, LLC
Fe C Tab PlusBoca Pharmacal, LLC
Fem - ControlMetagenics, Inc.
Feminex 300 TabSantÉ Naturelle (Ag) LtÉe
Feminique W Iron and Calcium TabStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Femitab TabLe Groupe Prodeal Ltee
Feriva FaAvion Pharmaceuticals, Llc
Fero Grad 500Abbott Laboratories, Limited
Ferra Naka Plus VitaminsNaka Sales Ltd.
Ferralet 90Mission Pharmacal Company
Ferrous SulfateMartin Ekwealor Pharmaceuticals, Inc.
Fib-C MeltsApm Products Pty Ltd.
Flinstones Multiple Plus IronMiles Canada Inc. Consumer Health Care Division
Flintstones Multiple Vitamins Plus IronBayer Inc Consumer Care
Floradix Formula LiqFlora Manufacturing And Distributing Ltd.
Floravit - SyrFlora Manufacturing And Distributing Ltd.
Folcaps Care OneMidlothian Laboratories
Folcaps Omega-3Midlothian Laboratories
Folet OnePronova Corporation
Foltabs PrenatalMidlothian Laboratories
For Kids Only Chewable Multivit. Plus IronKsl Pharmaceuticals
Formula Fm Vitamins & Minerals TabMetagenics, Inc.
Formula IntBalance Plus, Inc.
Formule No 204 Profil TabPharmalab Inc.
FortiplexSantÉ Naturelle (Ag) LtÉe
Garfield Chewable Multivits Plus Iron TabWhitehall Robins Inc.
Gestamine ComprimesLab Nadeau LtÉe, Division Of Technilab Inc.
Hemarexin TabLab Bio Chimique Inc.,Division Of Technilab Pharma Inc.
HematogenNnodum Pharmaceuticals
Hematogen FaNnodum Pharmaceuticals
Hematogen ForteNnodum Pharmaceuticals
Heparos Ampoules BuvablesDesbergers LtÉe, Division Of Technilab Inc.
Hi Potency B Complex W Chelated MineralsKlaire Labs Inc.
Hormodausse Plus Calc Et D TabLaboratoires Charton Laboratories
Hypo Vites TabPharmetics (2011) Inc
Iberet 500Abbott Laboratories, Limited
Iferex 150 ForteNnodum Pharmaceuticals
Inatal AdvanceNnodum Pharmaceuticals
Inatal UltraNnodum Pharmaceuticals
Integra FUs Pharmaceutical Corporation
Integra PlusUs Pharmaceutical Corporation
Iron 25mg With Vit B-cmplx, Vit C, Cu & MoQuest Vitamins A Div Of Purity Life Health Products
Iron ComplexPremier Plus Supplements Inc.
Iron IINutrilite, A Division Of Access Business Group, Llc
Iron Plus Manganese, B12, Folic Acid & CNatural Factors Nutritional Products Ltd.
Iron Plus TabSwiss Herbal Remedies Ltd.
Iron Vitamins B6,b12,c,folic Acid TabLaboratoire Lalco Inc.
Iron W Zinc Chelated W Liver TabTrophic Canada Ltd.
Iron With Vitamins TabEnrich International
Junel Fe 24Teva Pharmaceuticals USA Inc
Kanga-kid Multi-vitamin & MineralLacombe Drugs (1992) Ltd
Kanga-kid Vitamins & IronLacombe Drugs (1992) Ltd
Kanga-V Multivitamins & MineralsLacombe Drugs (1992) Ltd
Kids Stuff With Iron TabletsVita Health Products Inc
Livron Plus AmpouleMedic Laboratory LtÉe
Lysamine Diet Supp Amp-tabWelcker Lyster Ltd., Division Of Technilab Inc.
Maltlevol 12 LiqCarter Horner Corp.
Maltlevol LiqCarter Horner Corp.
Maxaron ForteCentrix Pharmaceutical, Inc,
MaxfePronova Corporation
Menocal TabLes Aliments Nutri Source Inc.
MgkHorizon SantÉ International Inc.
Mor-vites TabPharmetics (2011) Inc
Multi RolRolmex International Inc.
Multi Vitamin & MineralsWn Pharmaceuticals Ltd.
Multi Vitamin Drops With Fluoride and IronSeton Pharmaceuticals
Multi Vitamin Drops With Fluoride With IronStratus Pharmaceuticals
Multi Vitamin Plus IronWn Pharmaceuticals Ltd.
Multi Vitamin-mineral FormulaVita Health Products Inc
Multi Vitamin, Iron and FluorideLibertas Pharma, Inc.
Multi Vitamins & MineralsWn Pharmaceuticals Ltd.
Multi-vit With Fluoride and IronQualitest Pharmaceuticals
Multi-vitamin Fluoride and Iron DropsBoca Pharmacal, LLC
Multi-vitamins With MineralsWn Pharmaceuticals Ltd.
Multimineral ChelatesW.R. Enterprises Inc.
Multiple Vitamin Plus Minerals TabHall Laboratories, Ltd.
Multiple Vitamins and Minerals TabRandle Labs Inc.
Multiple Vitamins Plus Iron for WomenPharmetics (2011) Inc
Multiple Vitamins Plus Iron TabHall Laboratories, Ltd.
Multiple Vitamins W Iron TabStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Multiple Vitamins W Minerals TabStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Multiple Vitamins With IronStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Multiple Vitamins With Minerals TabletsPharmetics (2011) Inc
Multivitamines Et MinerauxLe Groupe M. Vachon Inc.
Multivitamines Plus Fer Pour Enfants (chewable Tablets)Laboratoire Lalco Inc.
Multivitamins W IronRandle Labs Inc.
Nata KompleteWh Nutritionals, Llc
NatafortMission Pharmacal Company
NataviteSchein Pharmaceutical Canada Inc.
Natelle OneMEDA Pharmaceuticals
Neo-vites & Minerals TabNeolab Inc
Nexa PlusUpsher Smith Laboratories, Inc.
Nexa Select Rx Prenatal Vitamin With Plant-based DHAUpsher Smith Laboratories, Inc.
Niron KompleteWh Nutritionals, Llc
NuferaCar Win Pharmaceutical Associates, Llc
Nutrifer Plus TabletsWyeth Ayerst Canada Inc.
O-cal Fa MultivitaminPharmics, Inc.
O-cal Prenatal VitaminPharmics, Inc.
One A Day Advance AdultsBayer Inc Consumer Care
One A Day Advance FemBayer Inc Consumer Care
One A Day TabCountry Health Laboratories Ltd.
Orange Flavored Crystal Chews TabJeunique International Inc.
Orifer FSanofi Aventis Canada Inc
Paramettes Chewable Multivitamins Plus IronWyeth Ayerst Canada Inc.
Paramettes Chewable Multivits With Iron TabWhitehall Robins Inc.
Paramettes Multivits Plus Iron Tab (teens)Whitehall Robins Inc.
Paramettes SyrupWyeth Ayerst Canada Inc.
Permathene-12 - CapletCCA Industries, Inc.
Phosthenine Vitamines Et Fer (ampoules Buvable)Laboratoires Cortunon Inc.
Phytofortis + Calcium A-DProduits Phyto Inc.
PhytopureLaboratoire Lalco Inc.
Pnv Ferrous Fumarate Docusate Folic AcidVirtus Pharmaceuticals LLC
Pnv Prenatal Plus MultivitaminSancilio & Company Inc
Pnv Prenatal VitaminSancilio & Company Inc
Pnv Prenatal Vitamin Plus Vitamin ASancilio & Company Inc
Pnv-dhaAcella Pharmaceuticals, LLC
Pnv-selectAcella Pharmaceuticals, LLC
PregvitDuchesnay Inc
Pregvit Folic 4Duchesnay Inc
Pregvit Folic 5Duchesnay Inc
PrenaissanceAcella Pharmaceuticals, LLC
Prenaissance PlusAcella Pharmaceuticals, LLC
Prenatal 19Nationwide Laboratories, LLC
Prenatal Chelated MineralUsana Health Sciences, Inc.
Prenatal PlusBlenheim Pharmacal, Inc.
Prenatal Plus IronMajor Pharmaceuticals
Prenatal Vitamins Plusbryant ranch prepack
Prenatal Vitamins Plus Low IronPatrin Pharma, Inc.
Prenate EliteAvion Pharmaceuticals, Llc
Prenate EnhanceAvion Pharmaceuticals, Llc
Prenate RestoreAvion Pharmaceuticals, Llc
Prenavite ForteAllen & Hanburys A Glaxo Canada Ltd. Co.
Prenavite Forte TabletsRoberts Pharmaceutical Canada Inc.
Prenavite TabletsRoberts Pharmaceutical Canada Inc.
PreplusVirtus Pharmaceuticals LLC
PretabVirtus Pharmaceuticals LLC
Prevencal 600 + D Et FerLaboratoire Lalco Inc.
Purevit Dualfe PlusPure Tek Corporation
Q.T. Vitamin and Mineral Drink MixGarden State Nutritionals
Reaphirm Plant Source DHAEverett Laboratories, Inc.
Revitex Ampoules Et ComprimesLes Produits Gerbex Inc.
Revival 1 TabBio Vita
Se-care ChewableSeton Pharmaceuticals
Se-natal 19Seton Pharmaceuticals
Se-natal 19 ChewableSeton Pharmaceuticals
Se-natal OneSeton Pharmaceuticals
Se-tan DHASeton Pharmaceuticals
Se-tan PlusSeton Pharmaceuticals
Somarexin and C 1000Laboratoire Lalco Inc.
Spectrum 2 CapNf Formulas Inc.
Stress B Complex With C, E & IronPharmavite Llc
Stress Formula + IronVita Health Products Inc
Strovite Forte CapletEverett Laboratories, Inc.
Super Daily No 2W.R. Enterprises Inc.
Super Vitalex Ampoule BuvableCarmaran LtÉe
Supplement De FerLand Art Inc.
Supravite 10ml AmpouleNobel Pharm Enr.
Supravite Bouteille 250mlNobel Pharm Enr.
Supravite C 1000Nobel Pharm Enr.
Supravite Stress Avec Vit E Et FerPharmalab Inc.
Surbex-500 With IronAbbott Laboratories, Limited
Swical-energy-2Les Laboratoires Swisse Inc.
TandemUs Pharmaceutical Corporation
Tandem - FUs Pharmaceutical Corporation
Tandem DHAUs Pharmaceutical Corporation
Tandem ObUs Pharmaceutical Corporation
Tandem PlusUs Pharmaceutical Corporation
Tini-cal AmpoulesPharmetics (2011) Inc
Tl-hem 150Trigen Laboratories, Inc.
Toni Com LiqVitalab
Tonicol Et A-D-C Ampoules/comprimesDistributions Multi Pro Inc.
Tri-vit With Fluoride and Iron DropsQualitest Pharmaceuticals
TriadvanceTrigen Laboratories, Inc.
Tricare PrenatalMedecor Pharma, Llc
TriconNnodum Pharmaceuticals
Trinatal GtTrigen Laboratories, Inc.
Ultimatecare One NfTrigen Laboratories, Inc.
Ultra EnerforceNutribon (1986) Inc.
Viamon Ampoules Et ComprimesLab Nadeau LtÉe, Division Of Technilab Inc.
Vimeral TabIcn Canada Ltd.
Virt-PNVirtus Pharmaceuticals
Virt-PN DHAVirtus Pharmaceuticals
Virt-PN PlusVirtus Pharmaceuticals LLC
Vita - Gl CapsulesAnton Hubner Gmbh & Co.
Vitafer - LiqFrega Inc.
Vitafol CapletEverett Laboratories, Inc.
Vitafol NanoEverett Laboratories, Inc.
Vitafol Ob CapletEverett Laboratories, Inc.
Vitafol OneEverett Laboratories, Inc.
Vitafol PlusEverett Laboratories, Inc.
Vitafol UltraEverett Laboratories, Inc.
Vitamine Du Groupe B Plus Fer - LiqPharmalab Inc.
Vitamins W Iron ChewableStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Vp Ch PlusVirtus Pharmaceuticals LLC
Vp Ch UltraVirtus Pharmaceuticals LLC
Vp-CH-pnvVirtus Pharmaceuticals
Zatean-CHTrigen Laboratories, Inc.
Salts
Name/CASStructureProperties
ferrous ascorbate
Thumb
  • InChI Key: RFBYLSCVRUTUSB-ZZMNMWMASA-N
  • Monoisotopic Mass: 407.999118109
  • Average Mass: 408.093
DBSALT000075
ferrous fumarate
Thumb
  • InChI Key: PMVSDNDAUGGCCE-TYYBGVCCSA-L
  • Monoisotopic Mass: 169.930250685
  • Average Mass: 169.901
DBSALT000079
ferrous gluconate
299-29-6
Thumb
  • InChI Key: QDUZQOIJXPPTLY-GMBKLUGCSA-N
  • Monoisotopic Mass: 448.051547609
  • Average Mass: 448.156
DBSALT000080
ferrous glycine sulfate
14729-84-1
Thumb
  • InChI Key: YJYOLOWXCPIBSY-UHFFFAOYSA-L
  • Monoisotopic Mass: 301.950728129
  • Average Mass: 302.041
DBSALT000081
ferrous succinate
Thumb
  • InChI Key: MDXRFOWKIZPNTA-UHFFFAOYSA-N
  • Monoisotopic Mass: 173.961550813
  • Average Mass: 173.933
DBSALT000083
ferrous sulfate
Thumb
  • InChI Key: BAUYGSIQEAFULO-UHFFFAOYSA-L
  • Monoisotopic Mass: 151.886671311
  • Average Mass: 151.908
DBSALT000084
Categories
UNIIE1UOL152H7
CAS number7439-89-6
WeightAverage: 55.845
Monoisotopic: 55.934942133
Chemical FormulaFe
InChI KeyInChIKey=XEEYBQQBJWHFJM-UHFFFAOYSA-N
InChI
InChI=1S/Fe
IUPAC Name
iron
SMILES
[Fe]
Taxonomy
DescriptionThis compound belongs to the class of inorganic compounds known as homogeneous transition metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a transition metal atom.
KingdomInorganic compounds
Super ClassHomogeneous metal compounds
ClassHomogeneous transition metal compounds
Sub ClassNot Available
Direct ParentHomogeneous transition metal compounds
Alternative ParentsNot Available
Substituents
  • Homogeneous transition metal
  • Acyclic compound
Molecular FrameworkAcyclic compounds
External Descriptors
Pharmacology
IndicationUsed in preventing and treating iron-deficiency anemia.
PharmacodynamicsThe major activity of supplemental iron is in the prevention and treatment of iron deficiency anemia. Iron has putative immune-enhancing, anticarcinogenic and cognition-enhancing activities.
Mechanism of actionIron is necessary for the production of hemoglobin. Iron-deficiency can lead to decreased production of hemoglobin and a microcytic, hypochromic anemia.
Related Articles
AbsorptionThe efficiency of absorption depends on the salt form, the amount administered, the dosing regimen and the size of iron stores. Subjects with normal iron stores absorb 10% to 35% of an iron dose. Those who are iron deficient may absorb up to 95% of an iron dose.
Volume of distributionNot Available
Protein bindingNot Available
MetabolismNot Available
Route of eliminationNot Available
Half lifeNot Available
ClearanceNot Available
ToxicityAcute iron overdosage can be divided into four stages. In the first stage, which occurs up to six hours after ingestion, the principal symptoms are vomiting and diarrhea. Other symptoms include hypotension, tachycardia and CNS depression ranging from lethargy to coma. The second phase may occur at 6-24 hours after ingestion and is characterized by a temporary remission. In the third phase, gastrointestinal symptoms recur accompanied by shock, metabolic acidosis, coma, hepatic necrosis and jaundice, hypoglycemia, renal failure and pulmonary edema. The fourth phase may occur several weeks after ingestion and is characterized by gastrointestinal obstruction and liver damage. In a young child, 75 milligrams per kilogram is considered extremely dangerous. A dose of 30 milligrams per kilogram can lead to symptoms of toxicity. Estimates of a lethal dosage range from 180 milligrams per kilogram and upwards. A peak serum iron concentration of five micrograms or more per ml is associated with moderate to severe poisoning in many.
Affected organisms
  • Humans and other mammals
Pathways
PathwayCategorySMPDB ID
Nucleotide Sugars MetabolismMetabolicSMP00010
Galactose MetabolismMetabolicSMP00043
Pyrimidine MetabolismMetabolicSMP00046
Tryptophan MetabolismMetabolicSMP00063
Retinol MetabolismMetabolicSMP00074
Alendronate Action PathwayDrug actionSMP00095
Zoledronate Action PathwayDrug actionSMP00107
Tyrosinemia Type IDiseaseSMP00218
Cerebrotendinous Xanthomatosis (CTX)DiseaseSMP00315
Vitamin A DeficiencyDiseaseSMP00336
Hereditary Coproporphyria (HCP)DiseaseSMP00342
Disulfiram Action PathwayDrug actionSMP00429
Carnitine SynthesisMetabolicSMP00465
Galactosemia IIIDiseaseSMP00496
Tyrosine hydroxylase deficiencyDiseaseSMP00497
Wolman diseaseDiseaseSMP00511
Catecholamine BiosynthesisMetabolicSMP00012
Cysteine MetabolismMetabolicSMP00013
Pentose Phosphate PathwayMetabolicSMP00031
Rosuvastatin Action PathwayDrug actionSMP00092
Fluvastatin Action PathwayDrug actionSMP00119
GalactosemiaDiseaseSMP00182
Congenital Erythropoietic Porphyria (CEP) or Gunther DiseaseDiseaseSMP00345
Porphyria Variegata (PV)DiseaseSMP00346
Tyrosinemia Type 2 (or Richner-Hanhart syndrome)DiseaseSMP00369
Tyrosinemia Type 3 (TYRO3)DiseaseSMP00370
CHILD SyndromeDiseaseSMP00387
Galactosemia II (GALK)DiseaseSMP00495
Hyper-IgD syndromeDiseaseSMP00509
Transaldolase deficiencyDiseaseSMP00520
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.9838
Blood Brain Barrier+0.9733
Caco-2 permeable+0.7354
P-glycoprotein substrateNon-substrate0.885
P-glycoprotein inhibitor INon-inhibitor0.9787
P-glycoprotein inhibitor IINon-inhibitor0.9858
Renal organic cation transporterNon-inhibitor0.9108
CYP450 2C9 substrateNon-substrate0.8466
CYP450 2D6 substrateNon-substrate0.8259
CYP450 3A4 substrateNon-substrate0.8158
CYP450 1A2 substrateNon-inhibitor0.8807
CYP450 2C9 inhibitorNon-inhibitor0.9373
CYP450 2D6 inhibitorNon-inhibitor0.9708
CYP450 2C19 inhibitorNon-inhibitor0.9553
CYP450 3A4 inhibitorNon-inhibitor0.988
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.882
Ames testNon AMES toxic0.9633
CarcinogenicityCarcinogens 0.664
BiodegradationReady biodegradable0.7326
Rat acute toxicity2.0135 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9547
hERG inhibition (predictor II)Non-inhibitor0.9746
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Pharmacoeconomics
ManufacturersNot Available
Packagers
Dosage forms
FormRouteStrength
Liquid; capsuleoral
Capsuleoral33 mg
Tabletoral25 mg
Tabletoral18 mg
Tablet
Tabletoral
Liquidintramuscular; intravenous50 mg
Tablet, chewableoral
Tabletoral28 mg
Liquidoral16.7 mg
Solutionintravenous30 mg
Dropsoral125 mg
Tabletoral65 mg
Tablet (extended-release)oral
Tablet (extended-release)oral105 mg
Tablet, film coatedoral
Tabletoral200 mg
Elixiroral220 mg/5mL
Tabletoral325 mg/1
Tabletoral65 mg/1
Tablet, film coatedoral325 mg/1
Tablet (enteric-coated)300 mg
Tabletoral325 mg
Tablet300 mg
Syruporal35 mg
Syruporal
Capsule (sustained-release)oral30 mg
Capsuleoral150 mg/1
Capsuleoral40 mg
Tabletoral30 mg
Tablet (extended-release)oral35 mg
Tabletoral37 mg
Capsuleoral50 mg
Tablet (extended-release)oral50 mg
Tablet, chewableoral15 mg/1
Tabletoral35 mg
Kit
Tablet (effervescent)oral
Tabletoral6 mg
Liquid; tabletoral
Solution/ dropsoral
Liquidoral
Capsule, gelatin coatedoral
Capsuleoral
Tablet (enteric-coated)oral300 mg
Tabletoral300 mg
Powderoral
Capsuleoral100 mg
Tablet (enteric-coated)oral60 mg
Solutionoral
Liquidintravenous20 mg
Tablet, coatedoral
Capsule, liquid filledoral
Prices
Unit descriptionCostUnit
Iron chews 15 mg tablet chew0.29USD tablet
Ferrous sulfate 28 mg tablet0.04USD tablet
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
PatentsNot Available
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point1538 °CNot Available
Predicted Properties
PropertyValueSource
logP-0.77ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Not Available
SpectraNot Available
References
Synthesis Reference

Walter Lugscheider, Paul Mullner, Wilhelm Schiffer, Alois Leutgob, “Arrangement for producing metals, such as molten pig iron, steel pre-material and ferroalloys.” U.S. Patent US4617671, issued 0000.

US4617671
General ReferencesNot Available
External Links
ATC CodesA11AA01B03AA01B03AA02B03AA03B03AA06B03AA07B03AA10B03AD02B03AD03B03AE01B03AE02B03AE03B03AE04
AHFS Codes
  • 20:04.00
  • 20:04.04
  • 88:29.00*
  • 92:02.00*
PDB EntriesNot Available
FDA labelDownload (100 KB)
MSDSDownload (75.6 KB)
Interactions
Drug Interactions
Drug
BenazeprilThe risk or severity of adverse effects can be increased when Benazepril is combined with Iron.
CaptoprilThe risk or severity of adverse effects can be increased when Captopril is combined with Iron.
CilazaprilThe risk or severity of adverse effects can be increased when Cilazapril is combined with Iron.
EnalaprilThe risk or severity of adverse effects can be increased when Enalapril is combined with Iron.
EnalaprilatThe risk or severity of adverse effects can be increased when Enalaprilat is combined with Iron.
FosinoprilThe risk or severity of adverse effects can be increased when Fosinopril is combined with Iron.
LisinoprilThe risk or severity of adverse effects can be increased when Lisinopril is combined with Iron.
MoexiprilThe risk or severity of adverse effects can be increased when Moexipril is combined with Iron.
PerindoprilThe risk or severity of adverse effects can be increased when Perindopril is combined with Iron.
QuinaprilThe risk or severity of adverse effects can be increased when Quinapril is combined with Iron.
RamiprilThe risk or severity of adverse effects can be increased when Ramipril is combined with Iron.
TrandolaprilThe risk or severity of adverse effects can be increased when Trandolapril is combined with Iron.
Food InteractionsNot Available
Comments
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Drug created on August 29, 2007 10:01 / Updated on May 17, 2016 16:24