You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on DrugBank.
Identification
NameRiboflavin Monophosphate
Accession NumberDB03247  (EXPT01458)
Typesmall molecule
Groupsexperimental
Description

A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues. [PubChem]

Structure
Thumb
SynonymsNot Available
SaltsNot Available
Brand namesNot Available
Brand mixturesNot Available
CategoriesNot Available
CAS number146-17-8
WeightAverage: 456.3438
Monoisotopic: 456.104614802
Chemical FormulaC17H21N4O9P
InChI KeyFVTCRASFADXXNN-YRGRVCCFSA-N
InChI
InChI=1S/C17H21N4O9P/c1-7-3-9-10(4-8(7)2)21(15-13(18-9)16(25)20-17(26)19-15)5-11(22)14(24)12(23)6-30-31(27,28)29/h3-4,11-12,14,22-24H,5-6H2,1-2H3,(H,20,25,26)(H2,27,28,29)/t11-,12-,14-/m1/s1
IUPAC Name
{[(2R,3R,4R)-5-{7,8-dimethyl-2,4-dioxo-2H,3H,4H,10H-benzo[g]pteridin-10-yl}-2,3,4-trihydroxypentyl]oxy}phosphonic acid
SMILES
CC1=CC2=C(C=C1C)N(C[C@@H](O)[C@@H](O)[C@H](O)COP(O)(O)=O)C1=NC(=O)NC(=O)C1=N2
Mass SpecNot Available
Taxonomy
KingdomOrganic Compounds
SuperclassHeterocyclic Compounds
ClassPteridines and Derivatives
SubclassAlloxazines and Isoalloxazines
Direct parentFlavins
Alternative parentsQuinoxalines; Pyrimidones; Toluenes; Pyrazines; Organophosphate Esters; Organic Phosphoric Acids; Secondary Alcohols; 1,2-Diols; Polyamines
Substituentsquinoxaline; toluene; pyrimidone; pyrimidine; pyrazine; benzene; phosphoric acid ester; organic phosphate; secondary alcohol; polyol; 1,2-diol; polyamine; alcohol; amine; organonitrogen compound
Classification descriptionThis compound belongs to the flavins. These are compounds containing a flavin (7,8-dimethyl-benzo[g]pteridine-2,4-dione) moiety, whose structure is characterized by an isoalloaxzine tricyclic ring.
Pharmacology
IndicationNot Available
PharmacodynamicsNot Available
Mechanism of actionNot Available
AbsorptionNot Available
Volume of distributionNot Available
Protein bindingNot Available
Metabolism
Route of eliminationNot Available
Half lifeNot Available
ClearanceNot Available
ToxicityNot Available
Affected organismsNot Available
Pathways
PathwayCategorySMPDB ID
UMP Synthase Deiciency (Orotic Aciduria)DiseaseSMP00219
Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency)DiseaseSMP00362
Beta-Alanine MetabolismMetabolicSMP00007
L-arginine:glycine amidinotransferase deficiencyDiseaseSMP00507
Ornithine Aminotransferase Deficiency (OAT Deficiency)DiseaseSMP00363
Arginine and Proline MetabolismMetabolicSMP00020
Pantothenate and CoA BiosynthesisMetabolicSMP00027
Hyperornithinemia with gyrate atrophy (HOGA)DiseaseSMP00505
Vitamin B6 MetabolismMetabolicSMP00017
Beta Ureidopropionase DeficiencyDiseaseSMP00172
Carnosinuria, carnosinemiaDiseaseSMP00493
Creatine deficiency, guanidinoacetate methyltransferase deficiencyDiseaseSMP00504
Dihydropyrimidinase DeficiencyDiseaseSMP00178
Prolidase Deficiency (PD)DiseaseSMP00207
Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency)DiseaseSMP00188
Ureidopropionase deficiencyDiseaseSMP00492
GABA-Transaminase DeficiencyDiseaseSMP00351
Doxorubicin Metabolism PathwayDrug metabolismSMP00650
MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy)DiseaseSMP00202
Hyperornithinemia-hyperammonemia-homocitrullinuria [HHH-syndrome]DiseaseSMP00506
Hyperprolinemia Type IIDiseaseSMP00360
Hyperprolinemia Type IDiseaseSMP00361
HypophosphatasiaDiseaseSMP00503
Prolinemia Type IIDiseaseSMP00208
Riboflavin MetabolismMetabolicSMP00070
Pyrimidine MetabolismMetabolicSMP00046
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
ADMET
Predicted ADMET features
Property Value Probability
Human Intestinal Absorption - 0.9125
Blood Brain Barrier - 0.7057
Caco-2 permeable - 0.6779
P-glycoprotein substrate Substrate 0.7661
P-glycoprotein inhibitor I Non-inhibitor 0.7188
P-glycoprotein inhibitor II Non-inhibitor 0.9704
Renal organic cation transporter Non-inhibitor 0.9373
CYP450 2C9 substrate Non-substrate 0.7163
CYP450 2D6 substrate Non-substrate 0.821
CYP450 3A4 substrate Substrate 0.523
CYP450 1A2 substrate Non-inhibitor 0.6006
CYP450 2C9 substrate Non-inhibitor 0.8359
CYP450 2D6 substrate Non-inhibitor 0.8907
CYP450 2C19 substrate Non-inhibitor 0.6667
CYP450 3A4 substrate Non-inhibitor 0.7421
CYP450 inhibitory promiscuity Low CYP Inhibitory Promiscuity 0.8922
Ames test Non AMES toxic 0.716
Carcinogenicity Non-carcinogens 0.8096
Biodegradation Not ready biodegradable 0.9737
Rat acute toxicity 2.4314 LD50, mol/kg Not applicable
hERG inhibition (predictor I) Weak inhibitor 0.9468
hERG inhibition (predictor II) Inhibitor 0.584
Pharmacoeconomics
ManufacturersNot Available
PackagersNot Available
Dosage formsNot Available
PricesNot Available
PatentsNot Available
Properties
Statesolid
Experimental PropertiesNot Available
Predicted Properties
PropertyValueSource
water solubility6.68e-01 g/lALOGPS
logP-0.78ALOGPS
logP-1.2ChemAxon
logS-2.8ALOGPS
pKa (strongest acidic)1.57ChemAxon
pKa (strongest basic)0.68ChemAxon
physiological charge-3ChemAxon
hydrogen acceptor count11ChemAxon
hydrogen donor count6ChemAxon
polar surface area201.58ChemAxon
rotatable bond count7ChemAxon
refractivity107.14ChemAxon
polarizability42.47ChemAxon
number of rings3ChemAxon
bioavailability0ChemAxon
rule of fiveNoChemAxon
Ghose filterNoChemAxon
Veber's ruleNoChemAxon
MDDR-like ruleYesChemAxon
Spectra
SpectraNot Available
References
Synthesis ReferenceNot Available
General ReferenceNot Available
External Links
ResourceLink
KEGG CompoundC00061
PubChem Compound5702760
PubChem Substance46507603
BindingDB50151057
ChEBI17621
ChEMBL
HETFMN
ATC CodesNot Available
AHFS CodesNot Available
PDB Entries
FDA labelNot Available
MSDSNot Available
Interactions
Drug InteractionsNot Available
Food InteractionsNot Available

Targets

1. Trimethylamine dehydrogenase

Kind: protein

Organism: Methylophilus methylotrophus

Pharmacological action: unknown

Components

Name UniProt ID Details
Trimethylamine dehydrogenase P16099 Details

2. Rubredoxin-oxygen oxidoreductase

Kind: protein

Organism: Desulfovibrio gigas

Pharmacological action: unknown

Components

Name UniProt ID Details
Rubredoxin-oxygen oxidoreductase Q9F0J6 Details

3. Riboflavin biosynthesis protein RibF

Kind: protein

Organism: Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

Pharmacological action: unknown

Components

Name UniProt ID Details
Riboflavin biosynthesis protein RibF Q9WZW1 Details

4. Morphinone reductase

Kind: protein

Organism: Pseudomonas putida

Pharmacological action: unknown

Components

Name UniProt ID Details
Morphinone reductase Q51990 Details

5. NADPH-flavin oxidoreductase

Kind: protein

Organism: Vibrio harveyi

Pharmacological action: unknown

Components

Name UniProt ID Details
NADPH-flavin oxidoreductase Q56691 Details

6. Ribosomal protein S6 kinase alpha-4

Kind: protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
Ribosomal protein S6 kinase alpha-4 O75676 Details

References:

  1. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. Pubmed

7. Phenazine biosynthesis protein PhzG

Kind: protein

Organism: Pseudomonas fluorescens

Pharmacological action: unknown

Components

Name UniProt ID Details
Phenazine biosynthesis protein PhzG Q51793 Details

8. Hydroxyacid oxidase 2

Kind: protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
Hydroxyacid oxidase 2 Q9NYQ3 Details

References:

  1. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. Pubmed

9. NAD(P)H dehydrogenase (quinone)

Kind: protein

Organism: Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)

Pharmacological action: unknown

Components

Name UniProt ID Details
NAD(P)H dehydrogenase (quinone) Q9RYU4 Details

10. Flavodoxin-1

Kind: protein

Organism: Escherichia coli (strain K12)

Pharmacological action: unknown

Components

Name UniProt ID Details
Flavodoxin-1 P61949 Details

11. Isopentenyl-diphosphate delta-isomerase

Kind: protein

Organism: Bacillus subtilis (strain 168)

Pharmacological action: unknown

Components

Name UniProt ID Details
Isopentenyl-diphosphate delta-isomerase P50740 Details

12. NADH dehydrogenase

Kind: protein

Organism: Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

Pharmacological action: unknown

Components

Name UniProt ID Details
NADH dehydrogenase Q60049 Details

13. FMN-binding protein

Kind: protein

Organism: Desulfovibrio vulgaris (strain Miyazaki F / DSM 19637)

Pharmacological action: unknown

Components

Name UniProt ID Details
FMN-binding protein Q46604 Details

14. Nitroreductase family protein

Kind: protein

Organism: Bacillus cereus (strain ATCC 14579 / DSM 31)

Pharmacological action: unknown

Components

Name UniProt ID Details
Nitroreductase family protein Q81EW9 Details

15. NADPH--cytochrome P450 reductase

Kind: protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
NADPH--cytochrome P450 reductase P16435 Details

References:

  1. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. Pubmed

16. Phosphopantothenoylcysteine decarboxylase

Kind: protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
Phosphopantothenoylcysteine decarboxylase Q96CD2 Details

References:

  1. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. Pubmed

17. PhzG

Kind: protein

Organism: Pseudomonas aeruginosa

Pharmacological action: unknown

Components

Name UniProt ID Details
PhzG O69755 Details

18. Ferredoxin-dependent glutamate synthase 2

Kind: protein

Organism: Synechocystis sp. (strain PCC 6803 / Kazusa)

Pharmacological action: unknown

Components

Name UniProt ID Details
Ferredoxin-dependent glutamate synthase 2 P55038 Details

19. Pyridoxine/pyridoxamine 5'-phosphate oxidase

Kind: protein

Organism: Escherichia coli (strain K12)

Pharmacological action: unknown

Components

Name UniProt ID Details
Pyridoxine/pyridoxamine 5'-phosphate oxidase P0AFI7 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed

20. Flavodoxin

Kind: protein

Organism: Clostridium beijerinckii

Pharmacological action: unknown

Components

Name UniProt ID Details
Flavodoxin P00322 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed

21. Oxygen-insensitive NAD(P)H nitroreductase

Kind: protein

Organism: Escherichia coli (strain K12)

Pharmacological action: unknown

Components

Name UniProt ID Details
Oxygen-insensitive NAD(P)H nitroreductase P38489 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed

22. Chorismate synthase

Kind: protein

Organism: Streptococcus pneumoniae (strain ATCC BAA-255 / R6)

Pharmacological action: unknown

Components

Name UniProt ID Details
Chorismate synthase P0A2Y7 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed

23. 2,4-dienoyl-CoA reductase [NADPH]

Kind: protein

Organism: Escherichia coli (strain K12)

Pharmacological action: unknown

Components

Name UniProt ID Details
2,4-dienoyl-CoA reductase [NADPH] P42593 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed

24. Dihydroorotate dehydrogenase A (fumarate)

Kind: protein

Organism: Lactococcus lactis subsp. cremoris

Pharmacological action: unknown

Components

Name UniProt ID Details
Dihydroorotate dehydrogenase A (fumarate) Q53ZE5 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed

25. Flavin reductase (NADPH)

Kind: protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
Flavin reductase (NADPH) P30043 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed

26. Hydroxyacid oxidase 1

Kind: protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
Hydroxyacid oxidase 1 Q9UJM8 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed
  3. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. Pubmed

27. Pyridoxine-5'-phosphate oxidase

Kind: protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
Pyridoxine-5'-phosphate oxidase Q9NVS9 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed
  3. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. Pubmed

28. Major NAD(P)H-flavin oxidoreductase

Kind: protein

Organism: Vibrio fischeri

Pharmacological action: unknown

Components

Name UniProt ID Details
Major NAD(P)H-flavin oxidoreductase P46072 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed

29. Riboflavin kinase

Kind: protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
Riboflavin kinase Q969G6 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed
  3. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. Pubmed

30. Oxygen-insensitive NADPH nitroreductase

Kind: protein

Organism: Escherichia coli (strain K12)

Pharmacological action: unknown

Components

Name UniProt ID Details
Oxygen-insensitive NADPH nitroreductase P17117 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed

31. Nitric oxide synthase, brain

Kind: protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
Nitric oxide synthase, brain P29475 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed
  3. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. Pubmed

32. Dihydroorotate dehydrogenase (quinone)

Kind: protein

Organism: Escherichia coli (strain K12)

Pharmacological action: unknown

Components

Name UniProt ID Details
Dihydroorotate dehydrogenase (quinone) P0A7E1 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed

33. Dihydropyrimidine dehydrogenase [NADP(+)]

Kind: protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
Dihydropyrimidine dehydrogenase [NADP(+)] Q12882 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed
  3. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. Pubmed

34. Dihydroorotate dehydrogenase (quinone), mitochondrial

Kind: protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
Dihydroorotate dehydrogenase (quinone), mitochondrial Q02127 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed
  3. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. Pubmed

35. Pentaerythritol tetranitrate reductase

Kind: protein

Organism: Enterobacter cloacae

Pharmacological action: unknown

Components

Name UniProt ID Details
Pentaerythritol tetranitrate reductase P71278 Details

36. FMN-dependent NADH-azoreductase

Kind: protein

Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

Pharmacological action: unknown

Components

Name UniProt ID Details
FMN-dependent NADH-azoreductase P63462 Details

37. Epidermin decarboxylase

Kind: protein

Organism: Staphylococcus epidermidis

Pharmacological action: unknown

Components

Name UniProt ID Details
Epidermin decarboxylase P30197 Details

38. FMN-dependent NADH-azoreductase

Kind: protein

Organism: Escherichia coli (strain K12)

Pharmacological action: unknown

Components

Name UniProt ID Details
FMN-dependent NADH-azoreductase P41407 Details

39. Chorismate synthase

Kind: protein

Organism: Helicobacter pylori (strain ATCC 700392 / 26695)

Pharmacological action: unknown

Components

Name UniProt ID Details
Chorismate synthase P56122 Details

40. Flavodoxin

Kind: protein

Organism: Nostoc sp. (strain PCC 7120 / UTEX 2576)

Pharmacological action: unknown

Components

Name UniProt ID Details
Flavodoxin P0A3D9 Details

41. Flavodoxin

Kind: protein

Organism: Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / NCIMB 8303)

Pharmacological action: unknown

Components

Name UniProt ID Details
Flavodoxin P00323 Details

42. Flavodoxin

Kind: protein

Organism: Synechococcus elongatus (strain PCC 7942)

Pharmacological action: unknown

Components

Name UniProt ID Details
Flavodoxin P10340 Details

43. Putative uncharacterized protein

Kind: protein

Organism: Streptococcus mutans serotype c (strain ATCC 700610 / UA159)

Pharmacological action: unknown

Components

Name UniProt ID Details
Putative uncharacterized protein Q8DW21 Details

44. Putative monooxygenase MoxC

Kind: protein

Organism: Bacillus subtilis (strain 168)

Pharmacological action: unknown

Components

Name UniProt ID Details
Putative monooxygenase MoxC O34974 Details

45. tRNA-dihydrouridine synthase

Kind: protein

Organism: Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

Pharmacological action: unknown

Components

Name UniProt ID Details
tRNA-dihydrouridine synthase Q9WXV1 Details

46. Protein NrdI

Kind: protein

Organism: Bacillus subtilis (strain 168)

Pharmacological action: unknown

Components

Name UniProt ID Details
Protein NrdI P50618 Details

47. Probable aromatic acid decarboxylase

Kind: protein

Organism: Escherichia coli O157:H7

Pharmacological action: unknown

Components

Name UniProt ID Details
Probable aromatic acid decarboxylase P69772 Details

48. (S)-mandelate dehydrogenase

Kind: protein

Organism: Pseudomonas putida

Pharmacological action: unknown

Components

Name UniProt ID Details
(S)-mandelate dehydrogenase P20932 Details

49. FMN-dependent NADPH-azoreductase

Kind: protein

Organism: Bacillus subtilis (strain 168)

Pharmacological action: unknown

Components

Name UniProt ID Details
FMN-dependent NADPH-azoreductase O07529 Details

50. Flavodoxin

Kind: protein

Organism: Helicobacter pylori (strain J99 / ATCC 700824)

Pharmacological action: unknown

Components

Name UniProt ID Details
Flavodoxin Q9ZK53 Details

51. Serine/threonine-protein kinase Sgk1

Kind: protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
Serine/threonine-protein kinase Sgk1 O00141 Details

References:

  1. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. Pubmed

52. Oxygen-insensitive NAD(P)H nitroreductase

Kind: protein

Organism: Enterobacter cloacae

Pharmacological action: unknown

Components

Name UniProt ID Details
Oxygen-insensitive NAD(P)H nitroreductase Q01234 Details

53. Nitric oxide reductase

Kind: protein

Organism: Moorella thermoacetica (strain ATCC 39073)

Pharmacological action: unknown

Components

Name UniProt ID Details
Nitric oxide reductase Q9FDN7 Details

54. Isopentenyl-diphosphate delta-isomerase

Kind: protein

Organism: Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)

Pharmacological action: unknown

Components

Name UniProt ID Details
Isopentenyl-diphosphate delta-isomerase Q746I8 Details

Enzymes

1. NADPH--cytochrome P450 reductase

Kind: protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
NADPH--cytochrome P450 reductase P16435 Details
Comments
comments powered by Disqus
Drug created on June 13, 2005 07:24 / Updated on September 16, 2013 17:20