Benign Prostatic Hyperplasia (BPH)

Also known as: Benign Prostatic Hyperplasia / Prostatauxe

DrugDrug NameDrug Description
DB00346AlfuzosinAn alpha-1 adrenergic antagonist used in the management of benign prostatic hypertrophy (BPH).
DB01126DutasterideAn antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) in adult males by inhibiting 5-alpha reductase.
DB01216FinasterideAn antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) and male pattern hair loss in adult males by inhibiting Type II 5-alpha reductase.
DB00457PrazosinAn alpha-blocker that causes a decrease in total peripheral resistance and is used to treat hypertension.
DB06207SilodosinAn alpha-1 adrenergic receptor antagonist used to treat symptoms associated with benign prostatic hyperplasia (BPH).
DB00820TadalafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension.
DB00706TamsulosinAn alpha-1A and alpha-1B adrenergic receptor antagonist used to treat benign prostatic hyperplasia, ureteral stones, prostatitis, and female voiding dysfunction.
DB01162TerazosinAn alpha-1 adrenergic antagonist used in the treatment of symptomatic benign prostatic hyperplasia and management of hypertension.
DrugDrug NameTargetType
DB00346AlfuzosinAlpha-1A adrenergic receptortarget
DB00346AlfuzosinAlpha-1B adrenergic receptortarget
DB00346AlfuzosinAlpha-1D adrenergic receptortarget
DB00346AlfuzosinCytochrome P450 3A4enzyme
DB00346AlfuzosinPotassium voltage-gated channel subfamily H member 2target
DB01126Dutasteride3-oxo-5-alpha-steroid 4-dehydrogenase 1target
DB01126Dutasteride3-oxo-5-alpha-steroid 4-dehydrogenase 2target
DB01126DutasterideSodium-dependent dopamine transportertransporter
DB01126DutasterideSynaptic vesicular amine transportertransporter
DB01126DutasterideSerum albumincarrier
DB01126DutasterideAlpha-1-acid glycoprotein 1carrier
DB01126DutasterideCytochrome P450 3A5enzyme
DB01216Finasteride3-oxo-5-alpha-steroid 4-dehydrogenase 1target
DB01216FinasterideCytochrome P450 3A4enzyme
DB01216Finasteride3-oxo-5-alpha-steroid 4-dehydrogenase 2target
DB01216Finasteride3-oxo-5-beta-steroid 4-dehydrogenasetarget
DB01216FinasterideCytochrome P450 3A5enzyme
DB01216FinasterideCytochrome P450 3A7enzyme
DB01216FinasterideSolute carrier family 12 member 5transporter
DB00457PrazosinAlpha-1A adrenergic receptortarget
DB00457PrazosinAlpha-1B adrenergic receptortarget
DB00457PrazosinAlpha-1D adrenergic receptortarget
DB00457PrazosinPotassium voltage-gated channel subfamily H member 2target
DB00457PrazosinAlpha-1-acid glycoprotein 1carrier
DB00457PrazosinSolute carrier family 22 member 1transporter
DB00457PrazosinSolute carrier family 22 member 3transporter
DB00457PrazosinP-glycoprotein 1transporter
DB00457PrazosinATP-binding cassette sub-family G member 2transporter
DB00457PrazosinAlpha-2A adrenergic receptortarget
DB00457PrazosinAlpha-2B adrenergic receptortarget
DB00457PrazosinAlpha-1 adrenergic receptorstarget
DB06207SilodosinAlpha-1D adrenergic receptortarget
DB06207SilodosinCytochrome P450 3A4enzyme
DB06207SilodosinP-glycoprotein 1transporter
DB06207SilodosinMultidrug resistance protein 3transporter
DB06207SilodosinAlpha-1A adrenergic receptortarget
DB06207SilodosinAlpha-1B adrenergic receptortarget
DB06207SilodosinUDP-glucuronosyltransferase 2B7enzyme
DB00820TadalafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00820TadalafilCytochrome P450 3A4enzyme
DB00820TadalafilDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11Atarget
DB00820TadalafilCytochrome P450 3A5enzyme
DB00706TamsulosinAlpha-1A adrenergic receptortarget
DB00706TamsulosinAlpha-1D adrenergic receptortarget
DB00706TamsulosinAlpha-1B adrenergic receptortarget
DB00706TamsulosinAlpha-1-acid glycoprotein 1carrier
DB00706TamsulosinCytochrome P450 2D6enzyme
DB00706TamsulosinCytochrome P450 3A4enzyme
DB01162TerazosinAlpha-1A adrenergic receptortarget
DB01162TerazosinAlpha-1B adrenergic receptortarget
DB01162TerazosinAlpha-1D adrenergic receptortarget
DB01162TerazosinPotassium voltage-gated channel subfamily H member 2target
DB01162TerazosinPotassium voltage-gated channel subfamily H member 6target
DB01162TerazosinPotassium voltage-gated channel subfamily H member 7target
DB01162TerazosinP-glycoprotein 1transporter
DB01162TerazosinTransforming growth factor beta-1target
DrugDrug NamePhaseStatusCount
DB00083Botulinum toxin type A0Completed1
DB00083Botulinum toxin type A0Withdrawn1
DB01126Dutasteride1Completed4
DB01126Dutasteride1Unknown Status1
DB01216Finasteride1Completed1
DB14317Pomegranate1Unknown Status1
DB01591Solifenacin1Completed3
DB00820Tadalafil1Completed5
DB00820Tadalafil1Unknown Status1
DB11812Talaporfin1Completed1
DB00706Tamsulosin1Completed6
DB00706Tamsulosin1Recruiting2
DB00083Botulinum toxin type A1 / 2Completed1
DB00898Ethanol1 / 2Completed1
DB05160Topsalysin1 / 2Completed1
DB00346Alfuzosin2Completed1
DB00083Botulinum toxin type A2Completed3
DB00083Botulinum toxin type A2Recruiting1
DB00482Celecoxib2Completed1
DB00590Doxazosin2Completed1
DB01126Dutasteride2Completed1
DB11674Equol2Completed1
DB12801Erteberel2Terminated1
DB00294Etonogestrel2Terminated1
DB01216Finasteride2Completed1
DB06266Lonidamine2Terminated1
DB05493NX-12072Completed1
DB12581Ozarelix2Terminated1
DB01229Paclitaxel2Active Not Recruiting1
DB00203Sildenafil2Completed1
DB06207Silodosin2Completed1
DB00820Tadalafil2Completed3
DB11812Talaporfin2Completed2
DB00706Tamsulosin2Completed2
DB00706Tamsulosin2Recruiting1
DB04937Tertomotide2Completed1
DB12747Tertomotide2Completed1
DB05160Topsalysin2Completed1
DB06267Udenafil2Withdrawn1
DB00862Vardenafil2Completed1
DB00083Botulinum toxin type A2 / 3Completed1
DB00820Tadalafil2 / 3Completed1
DB00346Alfuzosin3Completed1
DB00346Alfuzosin3Terminated1
DB01126Dutasteride3Completed1
DB01126Dutasteride3Terminated2
DB01216Finasteride3Completed2
DB01216Finasteride3Not Yet Recruiting1
DB01216Finasteride3Terminated2
DB01216Finasteride3Withdrawn1
DB06266Lonidamine3Terminated1
DB05493NX-12073Completed4
DB14360Saw palmetto3Completed1
DB06207Silodosin3Completed4
DB01591Solifenacin3Completed3
DB01591Solifenacin3Recruiting1
DB00820Tadalafil3Completed10
DB00820Tadalafil3Recruiting1
DB00706Tamsulosin3Completed10
DB00706Tamsulosin3Recruiting2
DB00706Tamsulosin3Terminated2
DB05160Topsalysin3Completed1
DB00346Alfuzosin4Completed2
DB00346Alfuzosin4Withdrawn1
DB00297Bupivacaine4Unknown Status1
DB00482Celecoxib4Withdrawn1
DB00537Ciprofloxacin4Completed1
DB00586Diclofenac4Recruiting1
DB00590Doxazosin4Unknown Status1
DB00590Doxazosin4Withdrawn1
DB01126Dutasteride4Completed7
DB01126Dutasteride4Terminated1
DB01126Dutasteride4Unknown Status1
DB01216Finasteride4Active Not Recruiting1
DB01216Finasteride4Unknown Status1
DB00798Gentamicin4Completed1
DB01002Levobupivacaine4Completed1
DB00281Lidocaine4Completed1
DB08893Mirabegron4Completed1
DB08893Mirabegron4Not Yet Recruiting1
DB01062Oxybutynin4Completed1
DB06207Silodosin4Completed4
DB01591Solifenacin4Completed3
DB00820Tadalafil4Completed1
DB00706Tamsulosin4Active Not Recruiting1
DB00706Tamsulosin4Completed9
DB00706Tamsulosin4Not Yet Recruiting1
DB00706Tamsulosin4Withdrawn1
DB01162Terazosin4Withdrawn1
DB00624Testosterone4Completed1
DB01036Tolterodine4Completed1
DB01036Tolterodine4Unknown Status1
DB00346AlfuzosinNot AvailableCompleted2
DB00633DexmedetomidineNot AvailableCompleted1
DB00590DoxazosinNot AvailableCompleted2
DB01126DutasterideNot AvailableCompleted4
DB01126DutasterideNot AvailableUnknown Status1
DB01216FinasterideNot AvailableCompleted1
DB06207SilodosinNot AvailableCompleted1
DB00706TamsulosinNot AvailableCompleted1
DB00706TamsulosinNot AvailableUnknown Status2
DB01162TerazosinNot AvailableCompleted1