Pain Management

Also known as: Managing pain

DrugDrug NameDrug Description
DB00316AcetaminophenAcetaminophen (paracetamol), also commonly known as _Tylenol_, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO) [A176318]. It is also used for its antipyretic effects, helping to reduce fever [F4124]. This drug was initially approved by the U.S. FDA in 1951 [FDA label] and is available in a variety of forms including syrup form, regular tablets, effervescent tablets, injection, suppository, and other forms [L5756, L5774, F4124], [FDA label]. Acetaminophen is often found combined with other drugs in more than 600 over the counter (OTC) allergy medications, cold medications, sleep medications, pain relievers, and other products [L5783]. Confusion about dosing of this drug may be caused by the availability of different formulas, strengths, and dosage instructions for children of different ages [L5783]. Due to the possibility of fatal overdose and liver failure associated with the incorrect use of acetaminophen, it is important to follow current and available national and manufacturer dosing guidelines while this drug is taken or prescribed [L5786, L5789], [FDA label].
DrugDrug NamePhaseStatusCount
DB00297Bupivacaine1Completed1
DB00668Epinephrine1Completed1
DB00281Lidocaine1Completed1
DB00316Acetaminophen1 / 2Completed1
DB00788Naproxen1 / 2Completed1
DB00193Tramadol1 / 2Completed1
DB00316Acetaminophen2Recruiting2
DB01050Ibuprofen2Recruiting1
DB00295Morphine2Recruiting1
DB00497Oxycodone2Recruiting1
DB00297Bupivacaine2 / 3Active Not Recruiting1
DB00633Dexmedetomidine2 / 3Active Not Recruiting1
DB01221Ketamine2 / 3Active Not Recruiting1
DB11121Chloroxylenol3Recruiting1
DB00575Clonidine3Recruiting1
DB00633Dexmedetomidine3Recruiting1
DB00668Epinephrine3Recruiting1
DB01221Ketamine3Recruiting1
DB00465Ketorolac3Recruiting1
DB00295Morphine3Active Not Recruiting1
DB00295Morphine3Recruiting2
DB00296Ropivacaine3Recruiting1
DB09153Sodium chloride3Recruiting1
DB00193Tramadol3Active Not Recruiting2
DB00193Tramadol3Recruiting1
DB00316Acetaminophen4Completed1
DB00316Acetaminophen4Not Yet Recruiting1
DB00316Acetaminophen4Recruiting3
DB00297Bupivacaine4Completed3
DB00297Bupivacaine4Recruiting3
DB00297Bupivacaine4Withdrawn1
DB00482Celecoxib4Completed1
DB00482Celecoxib4Recruiting1
DB00575Clonidine4Withdrawn1
DB01234Dexamethasone4Recruiting1
DB00586Diclofenac4Recruiting1
DB00668Epinephrine4Recruiting1
DB00668Epinephrine4Withdrawn1
DB00996Gabapentin4Recruiting1
DB00996Gabapentin4Withdrawn1
DB00956Hydrocodone4Recruiting1
DB01050Ibuprofen4Completed1
DB01050Ibuprofen4Not Yet Recruiting1
DB01221Ketamine4Recruiting1
DB01009Ketoprofen4Recruiting1
DB00465Ketorolac4Withdrawn1
DB01002Levobupivacaine4Recruiting1
DB00961Mepivacaine4Completed1
DB04817Metamizole4Recruiting1
DB00295Morphine4Completed1
DB00295Morphine4Recruiting2
DB00497Oxycodone4Not Yet Recruiting1
DB00497Oxycodone4Recruiting1
DB00296Ropivacaine4Withdrawn1
DB09153Sodium chloride4Completed1
DB13913BelladonnaNot AvailableCompleted1
DB00297BupivacaineNot AvailableRecruiting1
DB00586DiclofenacNot AvailableRecruiting1
DB00281LidocaineNot AvailableNot Yet Recruiting1
DB06802NepafenacNot AvailableRecruiting1
DB00296RopivacaineNot AvailableCompleted1
DB00296RopivacaineNot AvailableNot Yet Recruiting2
DB09153Sodium chlorideNot AvailableNot Yet Recruiting2
DB00193TramadolNot AvailableCompleted1