Thrombotic events

Also known as: Thrombosis / Thrombus / Thrombosis NOS

DrugDrug NameDrug Description
DB00054AbciximabAbciximab is a Fab fragment of the chimeric human-murine monoclonal antibody 7E3. Abciximab binds to the glycoprotein (GP) IIb/IIIa receptor of human platelets and inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor, and other adhesive molecules. It also binds to vitronectin (αvβ3) receptor found on platelets and vessel wall endothelial and smooth muscle cells.
DB00278ArgatrobanArgatroban is a direct, selective thrombin inhibitor. The American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous coronary intervention. Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients with HIT and prevent the formation of thrombi. Parental anticoagulants must be stopped and a baseline activated partial thromboplastin time must be obtained prior to administering argatroban.
DB00006BivalirudinBivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously. Because it can cause blood stagnation, it is important to monitor changes in hematocrit, activated partial thromboplastin time, international normalized ratio and blood pressure.
DB00063EptifibatideSynthetic cyclic hexapeptide that binds to platelet receptor glycoprotein and inhibits platelet aggregation. Derived from venom of the Southeastern pygmy rattlesnake (Sistrurus miliarus barbouri), eptifibatide is a cyclic heptapeptide that belongs to the class of arginin-glycin-aspartat-mimetics.
DrugDrug NamePhaseStatusCount
DB00758Clopidogrel0Recruiting1
DB00203Sildenafil0Not Yet Recruiting1
DB08816Ticagrelor0Recruiting1
DB00945Acetylsalicylic acid1Completed3
DB00009Alteplase1Terminated1
DB06605Apixaban1Completed3
DB00758Clopidogrel1Completed1
DB13150Coagulation factor VII human1Completed1
DB06695Dabigatran etexilate1Completed1
DB00343Diltiazem1Completed1
DB05202Egaptivon pegol1Completed1
DB01225Enoxaparin1Completed1
DB00569Fondaparinux1Completed1
DB11728Fondaparinux1Completed1
DB01167Itraconazole1Completed2
DB11312Protein C1Completed1
DB11311Prothrombin1Completed1
DB01045Rifampicin1Completed1
DB06228Rivaroxaban1Completed2
DB09145Water1Completed1
DB00945Acetylsalicylic acid2Completed1
DB04919Alfimeprase2Completed1
DB06605Apixaban2Completed1
DB06605Apixaban2Recruiting1
DB00006Bivalirudin2Completed1
DB00091Ciclosporin2Active Not Recruiting2
DB06695Dabigatran etexilate2Terminated1
DB06779Dalteparin2Terminated1
DB09075Edoxaban2Completed2
DB01225Enoxaparin2Completed1
DB01225Enoxaparin2Recruiting1
DB01225Enoxaparin2Terminated1
DB00001Lepirudin2Completed1
DB00848Levamisole2Active Not Recruiting2
DB00946Phenprocoumon2Terminated1
DB06822Tinzaparin2Terminated1
DB00682Warfarin2Recruiting1
DB00682Warfarin2Terminated1
DB00945Acetylsalicylic acid3Completed2
DB00945Acetylsalicylic acid3Not Yet Recruiting1
DB00945Acetylsalicylic acid3Recruiting1
DB00945Acetylsalicylic acid3Unknown Status1
DB04919Alfimeprase3Completed2
DB00009Alteplase3Not Yet Recruiting1
DB01076Atorvastatin3Unknown Status1
DB09258Bemiparin3Terminated1
DB00006Bivalirudin3Completed2
DB00758Clopidogrel3Completed2
DB00758Clopidogrel3Unknown Status1
DB00286Conjugated estrogens3Completed1
DB01225Enoxaparin3Completed1
DB00603Medroxyprogesterone acetate3Completed1
DB01022Phylloquinone3Completed2
DB00396Progesterone3Completed1
DB00015Reteplase3Not Yet Recruiting1
DB06228Rivaroxaban3Completed2
DB06228Rivaroxaban3Recruiting1
DB12823Tecarfarin3Not Yet Recruiting1
DB00682Warfarin3Completed2
DB00682Warfarin3Not Yet Recruiting1
DB00945Acetylsalicylic acid4Completed3
DB00945Acetylsalicylic acid4Recruiting1
DB00945Acetylsalicylic acid4Terminated1
DB00945Acetylsalicylic acid4Unknown Status1
DB00770Alprostadil4Unknown Status1
DB00009Alteplase4Terminated1
DB00009Alteplase4Unknown Status1
DB06605Apixaban4Recruiting1
DB00278Argatroban4Completed1
DB01076Atorvastatin4Unknown Status1
DB00758Clopidogrel4Completed1
DB00758Clopidogrel4Not Yet Recruiting1
DB00758Clopidogrel4Recruiting2
DB00758Clopidogrel4Terminated1
DB06695Dabigatran etexilate4Unknown Status1
DB11095Desirudin4Completed1
DB01225Enoxaparin4Unknown Status1
DB00016Erythropoietin4Completed1
DB01109Heparin4Completed1
DB11571Human Thrombin4Unknown Status1
DB00128L-Aspartic Acid4Terminated1
DB08813Nadroparin4Completed1
DB06209Prasugrel4Terminated1
DB06228Rivaroxaban4Recruiting1
DB06228Rivaroxaban4Unknown Status1
DB08816Ticagrelor4Completed1
DB08816Ticagrelor4Not Yet Recruiting1
DB08816Ticagrelor4Recruiting2
DB06822Tinzaparin4Completed2
DB00682Warfarin4Completed1
DB00682Warfarin4Recruiting1
DB00802AlfentanilNot AvailableRecruiting1
DB00479AmikacinNot AvailableRecruiting1
DB00513Aminocaproic AcidNot AvailableRecruiting1
DB01076AtorvastatinNot AvailableUnknown Status1
DB00559BosentanNot AvailableRecruiting1
DB01413CefepimeNot AvailableRecruiting1
DB00369CidofovirNot AvailableRecruiting1
DB00537CiprofloxacinNot AvailableRecruiting1
DB00758ClopidogrelNot AvailableUnknown Status1
DB00363ClozapineNot AvailableRecruiting1
DB06695Dabigatran etexilateNot AvailableEnrolling by Invitation1
DB01225EnoxaparinNot AvailableUnknown Status1
DB00828FosfomycinNot AvailableRecruiting1
DB00502HaloperidolNot AvailableRecruiting1
DB01109HeparinNot AvailableCompleted3
DB01109HeparinNot AvailableWithdrawn1
DB00598LabetalolNot AvailableRecruiting1
DB08815LurasidoneNot AvailableRecruiting1
DB00959MethylprednisoloneNot AvailableRecruiting1
DB01618MolindoneNot AvailableRecruiting1
DB00607NafcillinNot AvailableRecruiting1
DB01115NifedipineNot AvailableRecruiting1
DB00497OxycodoneNot AvailableRecruiting1
DB00312PentobarbitalNot AvailableRecruiting1
DB00728RocuroniumNot AvailableRecruiting1
DB00658SevelamerNot AvailableRecruiting1
DB00421SpironolactoneNot AvailableRecruiting1
DB00684TobramycinNot AvailableRecruiting1
DB00302Tranexamic acidNot AvailableRecruiting1
DB00512VancomycinNot AvailableRecruiting1
DB01339VecuroniumNot AvailableRecruiting1
DB00682WarfarinNot AvailableRecruiting1
DB00682WarfarinNot AvailableUnknown Status1
DB00246ZiprasidoneNot AvailableRecruiting1
DB00425ZolpidemNot AvailableRecruiting1