Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).
DrugDrug NameDrug Description
DB00008Peginterferon alfa-2aA modified form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses.
DB00022Peginterferon alfa-2bA purified form of human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C, genital warts, and some cancers.
DB00059PegaspargaseA modified form of L-asparagine amidohydrolase used to treat acute lymphoblastic leukemia, which is dependent on an external source of asparagine.
DB00375ColestipolA bile acid sequestrant used as an adjunct to diet and exercise to reduce LDL-C cholesterol levels in patients with primary hypercholesterolemia.
DB00638InulinHistorically used in an important medical test of renal function, specifically a measure of glomerular filtration rate. Sometimes used to help relieve symptoms of diabetes mellitus - a condition characterised...
DB00702IcodextrinAn iso-osmotic solution used for continuous peritoneal dialysis or automated peritoneal dialysis.
DB00840Hydroxypropyl celluloseA cellulose ether used to treat dry eyes.
DB00893Iron DextranAn iron supplement used to treat iron deficiency in patients who cannot take oral iron.
DB00908QuinidineA medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
DB01344TolevamerA potassium-binding resin used in the treatment of hyperkalemia.
DB01432CholestyramineA bile acid sequestrant used as an adjunct in the reduction of elevated serum cholesterol in patients with primary hypercholesterolemia, and for the relief of pruritus associated with partial biliary obstruction.
DB02061CellobioseA disaccharide consisting of two glucose units in beta (1-4) glycosidic linkage. Obtained from the partial hydrolysis of cellulose. [PubChem]
DB02237MaltotetraoseNot Available
DB02430Trehalose-6-PhosphateNot Available
DB02717CellotetraoseNot Available
DB03323MaltoseA dextrodisaccharide from malt and starch. It is used as a sweetening agent and fermentable intermediate in brewing. (Grant & Hackh's Chemical Dictionary, 5th ed)
DB04941CrofelemerAn antidiarrheal agent used for the symptomatic relief of drug-induced non-infectious diarrhea in adult patients with HIV/AIDS receiving antiretroviral therapy.
DB04978SP1049CIntended for the treatment of carcinoma of the oesophagus.
DB05321PEG-uricaseInvestigated for use/treatment in hyperuricemia.
DB05384Carbopol 974PInvestigated for use/treatment in contraception and HIV prevention.
DB05446LJP 1082Investigated for use/treatment in autoimmune diseases, strokes, and thrombosis.
DB05718Maxy-G34Investigated for use/treatment in adverse effects (chemotherapy) and neutropenics.
DB05899IT-101Investigated for use/treatment in cancer/tumors (unspecified) and solid tumors.
DB06206SugammadexA modified gamma cyclodextrin used to reverse neuromuscular blockade induced by vecuronium bromide and rocuronium bromide which are agents used for anesthesia.
DB06423EndostatinInvestigated for use/treatment in cancer/tumors (unspecified), macular degeneration, and diabetic retinopathy.
DB06439TyloxapolTyloxapol is an inhaled surfactant that assists in removing and liquefying and removing bronchopulmonary secretions with mucus and pus. Tyloxapol is administered either through nebulized solution or a stream of...
DB06611PegsunerceptInvestigated for use/treatment in rheumatoid arthritis.
DB06776Sodium cellulose phosphateSodium cellulose phosphate is used to treat hypercalcemia and hypercalciuria. It has been used to prevent kidney stones. This compound is an ion-exchange resin that can not be absorbed by...
DB06804Nonoxynol-9A vaginal spermicide used for the non-hormonal contraception in conjunction with other modes of contraception.
DB06811PolidocanolA sclerosing agent used for the treatment of uncomplicated spider veins and uncomplicated reticular veins, all less than 3 mm in diameter, in the lower extremity.
DB06812Povidone-iodineA topical antiseptic agent used for the treatment and prevention of infection in wounds.
DB08894PeginesatidePeginesatide is used for the treatment of anemia due to chronic kidney disease (CKD) in adult patients on dialysis
DB08904Certolizumab pegolA tumor necrosis factor (TNF) blocker used to treat a variety of autoimmune and autoinflammatory conditions like Crohn's disease, rheumatoid arthritis, active psoriatic arthritis, ankylosing spondylitis, axial spondyloarthritis, and plaque psoriasis.
DB08917Ferric carboxymaltoseAn iron replacement therapy used to treat iron deficiency anemia in adults with intolerance or inadequate clinical response to oral iron or those who have non-dialysis dependent chronic kidney disease.
DB09049NaloxegolA peripherally-selective opioid antagonist used to treat opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain.
DB09106Hydroxyethyl StarchA plasma volume substitute used to treat and prevent hypovolemia.
DB09107Methoxy polyethylene glycol-epoetin betaA synthetic erythropoiesis stimulating agent (ESA) used to treat anemia associated with chronic kidney disease.
DB09111PentastarchA plasma volume expander used as an adjunct in the management of shock due to hemorrhage, surgery, sepsis, burns or other trauma.
DB09122Peginterferon beta-1aAn interferon beta used to treat relapsing forms of multiple sclerosis.
DB09208PegloticaseA recombinant uricase used for the treatment of chronic gout in adult patients refractory to conventional therapy.
DB09255DextranA low molecular weight dextran used as an adjunctive treatment of shock or impending shock due to hemorrhage, burns, surgery or other trauma, as well as the prophylaxis of venous thrombosis and pulmonary embolism during high-risk medical procedures.
DB09287Polyethylene glycolA laxative used to treat constipation and used for bowel preparation before colonoscopies and other procedures.
DB09311PolycarbophilPolycarbophil is used to treat constipation and to help maintain regular bowel movements.
DB09507FerumoxsilNot Annotated
DB09508FerumoxidesNot Annotated
DB09512SimethiconeAn anti-flatulence agent used to relieve pressure, bloating, and symptoms referred to as gas.
DB10535Karaya gumAn extract from Karaya gum used in allergy testing.
DB10667TragacanthAn extract from Tragacanth used in allergy testing.
DB10852CarobAn extract from Carob used in allergy testing.
DB11059CarboxymethylcelluloseA compound used as an ophthalmic lubricant.
DB11060Polyvinyl alcoholA compound used as an ophthalmic lubricant.
DB11061PovidoneWhen in complex with iodine, indicated for inducing antisepsis for prevention of infection in minor cuts, scrapes, and burns.
DB11063Polysorbate 80It is used as a solubilizer, antimicrobial preservative and disinfectant .
DB11074DimethiconeAn ingredient used to treat dry and irritated eyes.
DB11075HypromelloseAn ingredient used in a wide variety of medications, and is not an approved medication.
DB11077Polyethylene glycol 400An ingredient used in a wide variety of medications, and is not an approved medication.
DB11120TurpentineA medication used to treat minor aches and pains of muscles and joints.
DB11158PectinPectin is used in food as a gelling agent and stabilizer. As a medical drug, it has obtained a great interest in its potential use as a source of dietary...
DB11161Polyethylene glycol 300Indicated as a lubricant in over-the-counter ophthalmic solutions to temporarily relieve redness, burning and irritation of the eyes.
DB11165RosinRosin is a solid form of resin obtained from pines and other plants, mostly conifers. It is prepared from heating fresh liquid resin to vaporize the volatile liquid terpene components....
DB11178Polysorbate 20Polysorbate 20 is a polysorbate-type nonionic surfactant used in many commercial, household and pharmaceutical products. It is composed of 20 repeated units of polyethylene glycol via ethoxylation. Polysorbate 20 is...
DB11223Tolu balsamNot Annotated
DB11228MethylcelluloseA compound used as a bulk forming laxative and is not an approved medication.
DB11234PoliglusamPoliglusam, or chitosan, is a linear polysaccharide consisting of D-glucosamine and N-acetyl-D-glucosamine. Naturally-occuring poliglusam is found in the cell walls of fungi, soil and sediments where it is produced from...
DB11252Poloxamer 407Poloxamer 407 is a polyoxyethylene polymer and hydrophilic non-ionic surfactant. It consists of a central hydrophobic block of polypropylene glycol that is flanked on each side by polyethylene glycol blocks,...
DB11333Poloxamer 188A medication used to clean wounds.
DB11417GleptoferronColloid solution of ferric hydroxide, dextran & glucoheptonic acid.
DB11451PoloxaleneEthylene oxide/propylene oxide copolymer is used as a food additive. It belongs to the family of Epoxides. These are compounds containing a cyclic ether with three ring atoms (one oxygen...
DB11482Balsam of PeruBalsam of Peru is found in diverse cosmetics and perfumes as well as a flavoring agent in cough syrups, lozenges, chewing gum, and candies. As a medical agent, balsam of...
DB11567Insulin peglisproNot Annotated
DB11585Drometrizole trisiloxaneAn UV ray absorbing agent used in sunscreens to protect skin from UV radiation.
DB11599Starch, cornCorn starch refers to the starch extracted from the corn grain that is commonly used as a food ingredient and chemical additive. Starch is any of a group of polysaccharides...
DB11602Hydroxyethyl celluloseAn ingredient used in formulations to alleviate irritation of the skin.
DB11854AstodrimerAstodrimer has been used in trials studying the treatment and prevention of Bacterial Vaginosis. It is a lysine-based dendrimer with naphthalene disulfonic acid surface groups.
DB120402-octyl cyanoacrylateDermabond has been investigated for the basic science of Wound Healing.
DB12310TrehaloseCabaletta has been used in trials studying the treatment of Oculopharyngeal Muscular Dystrophy.
DB12358EnbucrilateEnbucrilate is under investigation in clinical trial NCT02468206 (Secondary Prophylaxis of Gastric Variceal Bleed).
DB12521Methyl pyrrolidoneN Methyl Pyrrolidone is under investigation for the treatment of Multiple Myeloma.
DB12842PegamotecanPegamotecan has been used in trials studying the treatment of Cancer of Stomach, Sarcoma, Soft Tissue, and Gastroesophageal Cancer.
DB13128SizofiranA beta-D-glucan obtained from the Aphyllophoral fungus Schizophyllum commune. It is used as an immunoadjuvant in the treatment of neoplasms, especially tumors found in the stomach. Sizofiran has been used...
DB13446Guar gumNot Annotated
DB13477Sodium apolateNot Annotated
DB13480LentinanNot Annotated
DB13560DextranomerNot Annotated
DB13570Oxidized celluloseNot Annotated
DB13933Nonacog beta pegolA recombinant coagulation Factor IX derivative used to treat hemophilia B.
DB14091Carbomer homopolymer type CCarbomer homopolymer type C is a high molecular polyanionic substance tested for antiulcerogenic activity.
DB14124CyclomethiconeNot Annotated
DB14139Hydroxyethyl ethylcelluloseHydroxyethyl ethylcellulose modulates bacterial binding to salivary pellicle; moderately effective in preventing plaque formation.
DB14158Microcrystalline celluloseA polysaccharide with glucose units linked as in CELLOBIOSE. It is the chief constituent of plant fibers, cotton being the purest natural form of the substance. As a raw material,...
DB14326AmberAmber is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
DB09329Antihemophilic Factor (Recombinant), PEGylatedFor the management of hemophilia A (congenital factor VIII deficiency) [FDA label], . This medication is a human antihemophilic factor indicated in adolescent and adult patients (12 years and older)...
DB14684Calcium polycarbophilA bulk forming laxative used to treat constipation.
DB02078TriglymeTriethylene glycol dimethyl ether (also called triglyme) is a glycol ether used as a solvent.
DB02327Triethylene glycolNot Available
DB03995BetadexNot Available
DB14730Calaspargase pegolAn asparagine specific enzyme used to treat acute lymphoblastic leukemia.
DB06592PegargiminaseInvestigated for use/treatment in melanoma and hepatocellular carcinoma.
DB11313Phenyl trimethiconeNot Annotated
DB06496Dextrin 2-sulfateInvestigated for use/treatment in HIV prevention.
DB14767Peginterferon lambda-1aPeginterferon lambda-1a is under investigation in clinical trial NCT01754974 (Safety and Efficacy Study of Peginterferon Lambda-1a vs. Peginterferon Alfa-2a, Plus Ribavirin in Subjects With Genotype 1 Hepatitis C).
DB14771Polyacrylamide (crosslinked; 2 mole percent bisacrylamide)Polyacrylamide (crosslinked; 2 mole percent bisacrylamide) is under investigation in clinical trial NCT00629083 (Bulking Agents for the Treatment of Stress Urinary Incontinence in Females).
DB14832PolydioxanonePolydioxanone is under investigation in clinical trial NCT00998907 (PDS*Plus and Wound Infections After Laparotomy).
DB14836PolydextrosePolydextrose is under investigation in clinical trial NCT02258750 (Assessing a Polydextrose Containing Soup on Food Intake, Appetite and Biomarkers of Satiation and Satiety).
DB14927AmylopectinAmylopectin is under investigation in clinical trial NCT01708694 (Role of Slowly Digesible Starch on Diabetes Risk Factors).
DB14951Etirinotecan pegolEtirinotecan pegol is under investigation in clinical trial NCT01663012 (Phase II NKTR-102 In Bevacizumab-Resistant High Grade Glioma).
DB14953Firtecan pegolFirtecan pegol is under investigation in clinical trial NCT01036113 (A Phase 2 Study of EZN-2208 in Patients With Metastatic Breast Cancer).
DB15112Somatropin pegolSomatropin pegol is under investigation in clinical trial NCT00715689 (Dose Study in Growth Hormone Deficient Adults Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083).
DB15216AmyloseAmylose is under investigation in clinical trial NCT01027325 (Resistant Starch Insulin Sensitivity Trial).
DB15379Hydroxypropyl betadexHydroxypropyl betadex is under investigation in clinical trial NCT03471143 (Study of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type C).
DB15441Lulizumab pegolLulizumab pegol is under investigation in clinical trial NCT02843659 (Proof of Concept Study to Evaluate the Efficacy and Safety of BMS-931699 (Lulizumab) or BMS-986142 in Primary Sjögren's Syndrome).
DB00019PegfilgrastimA recombinant human granulocyte colony stimulating factor used to stimulate the production of neutrophils and prevent febrile neutropenia or infections after myelosuppressive chemotherapy.
DB11727EndostarEndostar is under investigation for the treatment of Nasopharyngeal Carcinoma. Endostar has been investigated for the treatment of Non-small Cell Lung Cancer.
DB11859BrexanoloneBrexanolone is a synthetic neuroactive steroid gamma-aminobutyric acid A (GABA(a)) receptor positive modulator indicated for the treatment of postpartum depression (PPD) in adult women [FDA Label][A176080, A176083, F4063, F4066, F4072].
DB13200LipegfilgrastimA medication used to reduce the duration of chemotherapy-induced neutropenia and incidence of febrile neutropenia in cytotoxic chemotherapy.
DB15037Poly(lactic acid)Poly(lactic acid) is under investigation in clinical trial NCT00126308 (Facial Lipoatrophy Trial: Immediate Versus Deferred Injections of Poly-L-Lactic Acid for HIV Facial Lipoatrophy).
DB15086OcrylateOcrylate is under investigation in clinical trial NCT01918059 (Cosmetic Outcome Study of Lid Laceration Repair With Suture Versus Tissue Adhesive).
DB15140BempegaldesleukinBempegaldesleukin is under investigation in clinical trial NCT03729245 (A Study of NKTR-214 in Combination With Nivolumab Compared With the Investigator's Choice of a Tyrosine Kinase Inhibitor (TKI) Therapy (Either Sunitinib...
DB15162PegilodecakinPegilodecakin is under investigation in clinical trial NCT03382912 (Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer).
DB15365PegbelferminPegbelfermin is under investigation in clinical trial NCT03486899 (A Study of Experimental Medication BMS-986036 in Adults With Nonalcoholic Steatohepatitis (NASH) and Stage 3 Liver Fibrosis).
DB15531Silk sericinNot Annotated
DrugDrug NameTargetType
DB00008Peginterferon alfa-2aInterferon alpha/beta receptor 2target
DB00008Peginterferon alfa-2aInterferon alpha/beta receptor 1target
DB00008Peginterferon alfa-2aCytochrome P450 1A2enzyme
DB00022Peginterferon alfa-2bInterferon alpha/beta receptor 1target
DB00022Peginterferon alfa-2bInterferon alpha/beta receptor 2target
DB00022Peginterferon alfa-2bCytochrome P450 1A2enzyme
DB00022Peginterferon alfa-2bCytochrome P450 2D6enzyme
DB00022Peginterferon alfa-2bCytochrome P450 2C9enzyme
DB00059PegaspargaseL-asparaginetarget
DB00059PegaspargaseThyroxine-binding globulincarrier
DB00375ColestipolBile acidstarget
DB00638InulinCycloinulo-oligosaccharide fructanotransferasetarget
DB00702IcodextrinPancreatic alpha-amylaseenzyme
DB00893Iron DextranHemoglobin subunit betatarget
DB00893Iron DextranHemoglobin subunit alphatarget
DB00893Iron DextranFerritin heavy chaintarget
DB00893Iron DextranFerritin light chaintarget
DB00893Iron DextranSerotransferrincarrier
DB00908QuinidineSodium channel protein type 5 subunit alphatarget
DB00908QuinidineAlpha-1-acid glycoprotein 1carrier
DB00908QuinidinePotassium voltage-gated channel subfamily H member 2target
DB00908QuinidinePotassium channel subfamily K member 1target
DB00908QuinidinePotassium channel subfamily K member 6target
DB00908QuinidineCytochrome P450 1A2enzyme
DB00908QuinidineCytochrome P450 2E1enzyme
DB00908QuinidineCytochrome P450 1A1enzyme
DB00908QuinidineCytochrome P450 2D6enzyme
DB00908QuinidineCytochrome P450 3A4enzyme
DB00908QuinidineCytochrome P450 3A7enzyme
DB00908QuinidineSolute carrier family 22 member 2transporter
DB00908QuinidineSolute carrier family 22 member 1transporter
DB00908QuinidineSolute carrier family 22 member 5transporter
DB00908QuinidineP-glycoprotein 1transporter
DB00908QuinidineSolute carrier organic anion transporter family member 1A2transporter
DB00908QuinidineSolute carrier family 22 member 8transporter
DB00908QuinidineCanalicular multispecific organic anion transporter 1transporter
DB00908QuinidineSolute carrier family 22 member 4transporter
DB00908QuinidineSolute carrier organic anion transporter family member 1B1transporter
DB00908QuinidineCytochrome P450 2B6enzyme
DB00908QuinidineCytochrome P450 2C9enzyme
DB00908QuinidineAlpha-1A adrenergic receptortarget
DB00908QuinidineAlpha-1B adrenergic receptortarget
DB00908QuinidineAlpha-1D adrenergic receptortarget
DB00908QuinidineBile salt export pumptransporter
DB00908QuinidineCytochrome P450 2C8enzyme
DB01344TolevamerPotassiumtarget
DB01432CholestyramineBile acidstarget
DB02061CellobioseEndoglucanase Gtarget
DB02061CellobioseEndoglucanase 5Atarget
DB02061CellobioseEndoglucanasetarget
DB02237MaltotetraoseGlucan 1,4-alpha-maltotetraohydrolasetarget
DB02237MaltotetraoseNeopullulanase 2target
DB02430Trehalose-6-PhosphateHTH-type transcriptional regulator TreRtarget
DB02717CellotetraoseCellulose 1,4-beta-cellobiosidasetarget
DB03323MaltoseCyclomaltodextrin glucanotransferasetarget
DB03323MaltoseAlpha-amylase 2Btarget
DB03323MaltoseBeta-amylasetarget
DB03323MaltoseMaltogenic alpha-amylasetarget
DB03323MaltoseMaltodextrin phosphorylasetarget
DB03323MaltoseMaltose-binding periplasmic proteintarget
DB03323MaltoseAlpha-glucosidasetarget
DB03323MaltoseMaltose binding proteintarget
DB03323MaltoseMalto-oligosyltrehalose trehalohydrolasetarget
DB04941CrofelemerCystic fibrosis transmembrane conductance regulatortarget
DB04941CrofelemerAnoctamin-1target
DB04978SP1049CDNA topoisomerase 2-alphatarget
DB05321PEG-uricaseUric acid degradation bifunctional proteintarget
DB05446LJP 1082Beta-2-glycoprotein 1target
DB06423Endostatin72 kDa type IV collagenasetarget
DB06423EndostatinMatrix metalloproteinase-9target
DB06423EndostatinCollagenase 3target
DB06423EndostatinFocal adhesion kinase 1target
DB06423EndostatinE-selectintarget
DB06423EndostatinCytochrome P450 19A1enzyme
DB06439TyloxapolLipoprotein lipasetarget
DB06776Sodium cellulose phosphateCalcium ionstarget
DB06804Nonoxynol-9Prostaglandin G/H synthase 2enzyme
DB08894PeginesatideErythropoietin receptortarget
DB08904Certolizumab pegolTumor necrosis factortarget
DB08904Certolizumab pegolAlcohol dehydrogenase [NADP(+)]enzyme
DB09049NaloxegolCytochrome P450 3A4enzyme
DB09049NaloxegolCytochrome P450 2D6enzyme
DB09049NaloxegolCytochrome P450 2C19enzyme
DB09049NaloxegolMu-type opioid receptortarget
DB09107Methoxy polyethylene glycol-epoetin betaErythropoietin receptortarget
DB09122Peginterferon beta-1aCytochrome P450 1A2enzyme
DB09208PegloticaseUric acidtarget
DB11059CarboxymethylcelluloseSolute carrier family 2, facilitated glucose transporter member 1target
DB11075HypromelloseEpithelial cell adhesion moleculetarget
DB11077Polyethylene glycol 400Oxidoreductase HTATIP2target
DB11077Polyethylene glycol 400Cytochrome P450 4A11enzyme
DB11077Polyethylene glycol 400Alcohol dehydrogenase class-3enzyme
DB11077Polyethylene glycol 400Sulfotransferase 1A1enzyme
DB11077Polyethylene glycol 400Ectonucleotide pyrophosphatase/phosphodiesterase family member 1target
DB11077Polyethylene glycol 400P-glycoprotein 1transporter
DB11120TurpentineMitogen-activated protein kinase 1target
DB11567Insulin peglisproCytochrome P450 1A2enzyme
DB11854AstodrimerEnvelope glycoprotein gp160target
DB13933Nonacog beta pegolCoagulation factor VIItarget
DB13933Nonacog beta pegolCoagulation factor VIIItarget
DB13933Nonacog beta pegolCoagulation factor Xtarget
DB09329Antihemophilic Factor (Recombinant), PEGylatedvon Willebrand factortarget
DB09329Antihemophilic Factor (Recombinant), PEGylatedvon Willebrand factorcarrier
DB02078TriglymeOuter-membrane lipoprotein LolBtarget
DB02078TriglymeProfilin-2target
DB02078TriglymeOuter-membrane lipoprotein LolBtarget
DB02078TriglymeUncharacterized proteintarget
DB02078TriglymeSerine acetyltransferasetarget
DB02078TriglymeTyrosine-protein kinase Fyntarget
DB02078TriglymePeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
DB02078TriglymeTranscriptional regulator, GntR familytarget
DB02078TriglymeABC transporter, periplasmic substrate-binding proteintarget
DB02078TriglymeTransketolasetarget
DB02327Triethylene glycolAcetolactate synthase, catabolictarget
DB02327Triethylene glycolArabinogalactan endo-1,4-beta-galactosidasetarget
DB02327Triethylene glycolPhosphoserine aminotransferasetarget
DB03995BetadexNeopullulanase 2target
DB03995BetadexMaltose-binding periplasmic proteintarget
DB03995BetadexMaltogenic amylasetarget
DB14730Calaspargase pegolL-asparaginetarget
DB00019PegfilgrastimGranulocyte colony-stimulating factor receptortarget
DB00019PegfilgrastimNeutrophil elastaseenzyme
DB11859BrexanoloneGABA-A receptor (anion channel)target
DB11859BrexanoloneAldose reductaseenzyme
DB13200LipegfilgrastimGranulocyte colony-stimulating factor receptortarget