Cytochrome P-450 CYP2E1 Inhibitors

DrugDrug NameDrug Description
DB00822DisulfiramA carbamate derivative used to treat alcohol addiction.
DB06595MidostaurinAn antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL).
DB00951IsoniazidAn antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis.
DB00257ClotrimazoleA topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
DB13174RheinNo approved indication.
DB09120ZucapsaicinA topical analgesic used as an adjunct to relieve severe pain of osteoarthritis of the knee in selected adult patients.
DB00486NabiloneA synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy.
DB00208TiclopidineA platelet aggregation inhibitor used in the prevention of conditions associated with thrombi, such as stroke and transient ischemic attacks (TIA).
DB01115NifedipineA dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension.
DB06201RufinamideAn antiepileptic drug used as adjunctive therapy to treat seizures associated with Lennox-Gastaut Syndrome (LGS).
DB01127EconazoleA topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor.
DB00503RitonavirAn HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.
DB01110MiconazoleAn antifungal used to treat fungal infections affecting the vagina, mouth and skin.
DB00184NicotineA stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation.
DB00356ChlorzoxazoneA drug with muscle relaxant properties that is used as an adjunct to physical therapy and analgesics to treat stiffness and pain caused by a variety of musculoskeletal conditions.
DB01213FomepizoleAn inhibitor of alcohol dehydrogenase used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning.
DB00118AdemetionineS-Adenosylmethionine (SAMe) is used as a drug in Europe for the treatment of depression, liver disorders, fibromyalgia, and osteoarthritis. It has also been introduced into the United States market as...
DB00818PropofolA medication used in general anesthesia and for sedation.
DB00969AlosetronA 5-HT3 antagonist used to treat diarrhea-predominant IBS.
DB04794BifonazoleUsed for the treatment of various topical fungal infections, including athlete's foot (tinea pedis).
DB01558BromazepamA short-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and severe anxiety.
DB00477ChlorpromazineA phenothiazine antipsychotic used to treat nausea, vomiting, preoperative anxiety, schizophrenia, bipolar disorder, and severe behavioral problems in children.
DB00501CimetidineA histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion.
DB01151DesipramineA tricyclic antidepressant used in the treatment of depression.
DB00586DiclofenacAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
DB01628EtoricoxibFor the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout.
DB00623FluphenazineA phenothiazine used to treat patients requiring long-term neuroleptic therapy.
DB00690FlurazepamA long-acting benzodiazepine with a rapid onset of action that is commonly used to treat insomnia.
DB00458ImipramineA tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis.
DB00883Isosorbide dinitrateA vasodilator used to treat angina in coronary artery disease.
DB01167ItraconazoleAn antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis.
DB01011MetyraponeA steroid 11-beta-monooxygenase inhibitor used to test hypothalamic-pituitary ACTH function.
DB02701NicotinamideAn ingredient found in a variety of cosmetic products.
DB00540NortriptylineA tricyclic antidepressant used in the treatment of depression.
DB01037SelegilineA monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's.
DB00203SildenafilA phosphodiesterase inhibitor used for the treatment of erectile dysfunction.
DB00259SulfanilamideA sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans.
DB01079TegaserodA serotonin-4 (5-HT4) receptor agonist indicated for the treatment of constipation predominant irritable bowel syndrome (IBS-C) specifically in women under the age of 65. There is currently no safety or efficacy data for use of tegaserol in men.
DB00763MethimazoleA thionamide antithyroid agent that inhibits the actions of thyroid peroxidase, leading to a reduction in thyroid hormone synthesis and amelioration of hyperthyroidism.
DB00679ThioridazineA phenothiazine antipsychotic used to treat schizophrenia and generalized anxiety disorder.
DB01007TioconazoleAn imidazole antifungal used to treat vulvovaginal candidiasis.
DB00752TranylcypromineA monoamine oxidase inhibitor used to treat major depressive disorder.
DB01586Ursodeoxycholic acidA bile acid used for the treatment of primary biliary cirrhosis (PBC), dissolution of radiolucent gallstones in patients with a functioning gallbladder, and treatment of hepatobiliary disorders associated with cystic fibrosis in pediatric patients.
DB00549ZafirlukastA leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma.
DB00255DiethylstilbestrolUsed in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery.
DB06370IndisulamInvestigated for use/treatment in lung cancer.
DB00041AldesleukinA recombinant analog of interleukin-2 used to induce an adaptive immune response in the treatment of renal cell carcinoma.
DB01068ClonazepamA long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, and seizures.
DB00829DiazepamA long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures.
DB01544FlunitrazepamFor short-term treatment of severe insomnias, that are not responsive to other hypnotics.
DB01595NitrazepamA long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, insomnia, and seizures.
DB08846Ellagic acidEllagic acid is being investigated for use in follicular lymphoma, brain injury in intrauterine growth restricted babies, obese adolescents, and solar lentigines.
DB11994DiacereinFor the treatment of osteoarthritis affecting the hip or knee .
DB06654SafinamideA MAO-B inhibitor used as an add-on treatment to levodopa/carbidopa for Parkinson's disease during "off" episodes.
DB00972AzelastineA histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis.
DB01191DexfenfluramineFor the management of obesity including weight loss and maintenance of weight loss in patients on a reduced calorie diet
DB01403MethotrimeprazineA phenothiazine used in the management of psychosis, particular those of schizophrenia, and manic phases of bipolar disorder.
DB09328VayarinADHD in children, hypertriglyceridemia [L1502, L1503].
DB02520DitiocarbA chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM.
DB00627NiacinA B vitamin used to treat hypertriglyceridemia and pellagra.
DB01173OrphenadrineA muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort.
DrugDrug NameTargetType
DB00822DisulfiramAldehyde dehydrogenase, mitochondrialtarget
DB00822DisulfiramCytochrome P450 2E1enzyme
DB00822DisulfiramDopamine beta-hydroxylasetarget
DB00822DisulfiramCytochrome P450 3A4enzyme
DB00822DisulfiramCytochrome P450 3A5enzyme
DB00822DisulfiramBile salt export pumptransporter
DB06595MidostaurinProtein kinase C alpha typetarget
DB06595MidostaurinVascular endothelial growth factor receptor 2target
DB06595MidostaurinMast/stem cell growth factor receptor Kittarget
DB06595MidostaurinPlatelet-derived growth factor receptor alphatarget
DB06595MidostaurinPlatelet-derived growth factor receptor betatarget
DB06595MidostaurinReceptor-type tyrosine-protein kinase FLT3target
DB06595MidostaurinCytochrome P450 3A Subfamilyenzyme
DB06595MidostaurinCytochrome P450 1A2enzyme
DB06595MidostaurinCytochrome P450 2B6enzyme
DB06595MidostaurinCytochrome P450 2C8enzyme
DB06595MidostaurinCytochrome P450 2C9enzyme
DB06595MidostaurinCytochrome P450 2C19enzyme
DB06595MidostaurinCytochrome P450 2D6enzyme
DB06595MidostaurinCytochrome P450 2E1enzyme
DB06595MidostaurinCytochrome P450 3A4enzyme
DB06595MidostaurinCytochrome P450 3A5enzyme
DB06595MidostaurinCytochrome P450 3A7enzyme
DB06595MidostaurinCytochrome P450 3A43enzyme
DB00951IsoniazidCatalase-peroxidasetarget
DB00951IsoniazidEnoyl-[acyl-carrier-protein] reductase [NADH]target
DB00951IsoniazidCytochrome P450 2E1enzyme
DB00951IsoniazidCytochrome P450 1A2enzyme
DB00951IsoniazidCytochrome P450 2C9enzyme
DB00951IsoniazidCytochrome P450 2D6enzyme
DB00951IsoniazidCytochrome P450 2C19enzyme
DB00951IsoniazidCytochrome P450 3A4enzyme
DB00951IsoniazidArylamine N-acetyltransferase 2enzyme
DB00951IsoniazidArylamine N-acetyltransferaseenzyme
DB00951IsoniazidCytochrome P450 2A6enzyme
DB00951IsoniazidCytochrome P450 2C8enzyme
DB00951IsoniazidCytochrome P450 2C8target
DB00951IsoniazidCytochrome P450 1A2target
DB00951IsoniazidCytochrome P450 3A4target
DB00951IsoniazidCytochrome P450 2C19target
DB00951IsoniazidDihydrofolate reductasetarget
DB00951IsoniazidSerum albumincarrier
DB00257ClotrimazoleIntermediate conductance calcium-activated potassium channel protein 4target
DB00257ClotrimazoleCytochrome P450 2D6enzyme
DB00257ClotrimazoleCytochrome P450 2C8enzyme
DB00257ClotrimazoleCytochrome P450 3A4enzyme
DB00257ClotrimazoleCytochrome P450 2B6enzyme
DB00257ClotrimazoleP-glycoprotein 1transporter
DB00257ClotrimazoleCytochrome P450 2A6enzyme
DB00257ClotrimazoleCytochrome P450 2C9enzyme
DB00257ClotrimazoleCytochrome P450 2E1enzyme
DB00257ClotrimazoleCytochrome P450 3A7enzyme
DB00257ClotrimazoleCytochrome P450 51target
DB00257ClotrimazoleNuclear receptor subfamily 1 group I member 2target
DB00257ClotrimazoleHydroxycarboxylic acid receptor 2target
DB00257ClotrimazoleBile salt export pumptransporter
DB00257ClotrimazoleSolute carrier organic anion transporter family member 1B1transporter
DB00257ClotrimazoleSolute carrier organic anion transporter family member 1B3transporter
DB00257ClotrimazoleErgosteroltarget
DB13174RheinOxysterols receptor LXR-alphatarget
DB13174RheinOxysterols receptor LXR-betatarget
DB13174RheinArylamine N-acetyltransferasetarget
DB13174RheinArachidonate 5-lipoxygenasetarget
DB13174RheinCytochrome P450 1A2enzyme
DB13174RheinCytochrome P450 3A Subfamilyenzyme
DB13174RheinCytochrome P450 2E1enzyme
DB13174RheinCytochrome P450 2C9enzyme
DB13174RheinCytochrome P450 2D6enzyme
DB09120ZucapsaicinTransient receptor potential cation channel subfamily V member 1target
DB09120ZucapsaicinCytochrome P450 1A2enzyme
DB09120ZucapsaicinCytochrome P450 2C19enzyme
DB09120ZucapsaicinCytochrome P450 2C9enzyme
DB09120ZucapsaicinCytochrome P450 2E1enzyme
DB00486NabiloneCannabinoid receptor 2target
DB00486NabiloneCannabinoid receptor 1target
DB00486NabiloneCytochrome P450 2E1enzyme
DB00486NabiloneCytochrome P450 2C8enzyme
DB00486NabiloneCytochrome P450 2C9enzyme
DB00208TiclopidineP2Y purinoceptor 12target
DB00208TiclopidineCytochrome P450 2C19enzyme
DB00208TiclopidineCytochrome P450 2B6enzyme
DB00208TiclopidineCytochrome P450 2C9enzyme
DB00208TiclopidineCytochrome P450 2D6enzyme
DB00208TiclopidineMyeloperoxidaseenzyme
DB00208TiclopidineCytochrome P450 1A2enzyme
DB00208TiclopidineCytochrome P450 2C8enzyme
DB00208TiclopidineCytochrome P450 2E1enzyme
DB01115NifedipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB01115NifedipineCytochrome P450 3A4enzyme
DB01115NifedipineCytochrome P450 2E1enzyme
DB01115NifedipineCytochrome P450 2D6enzyme
DB01115NifedipineCalmodulintarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit beta-2target
DB01115NifedipinePotassium voltage-gated channel subfamily A member 1target
DB01115NifedipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01115NifedipineCytochrome P450 1A2enzyme
DB01115NifedipineCytochrome P450 2A6enzyme
DB01115NifedipineCytochrome P450 2C8enzyme
DB01115NifedipineCanalicular multispecific organic anion transporter 2transporter
DB01115NifedipineP-glycoprotein 1transporter
DB01115NifedipineCanalicular multispecific organic anion transporter 1transporter
DB01115NifedipineCytochrome P450 1A1enzyme
DB01115NifedipineCytochrome P450 2B6enzyme
DB01115NifedipineNuclear receptor subfamily 1 group I member 2target
DB01115NifedipineSolute carrier organic anion transporter family member 1B1transporter
DB01115NifedipineBile salt export pumptransporter
DB06201RufinamideMetabotropic glutamate receptor 5target
DB06201RufinamideLiver carboxylesterase 1enzyme
DB06201RufinamideSodium channel protein type 9 subunit alphatarget
DB06201RufinamideSerum albumincarrier
DB06201RufinamideCytochrome P450 2E1enzyme
DB06201RufinamideCytochrome P450 3A4enzyme
DB01127EconazoleCytochrome P450 19A1enzyme
DB01127EconazoleCytochrome P450 2E1enzyme
DB01127EconazoleCytochrome P450 3A4enzyme
DB01127EconazoleCytochrome P450 51target
DB01127EconazoleNuclear receptor subfamily 1 group I member 2target
DB00503RitonavirHuman immunodeficiency virus type 1 proteasetarget
DB00503RitonavirCytochrome P450 2D6enzyme
DB00503RitonavirCytochrome P450 2C9enzyme
DB00503RitonavirCytochrome P450 2C19enzyme
DB00503RitonavirCytochrome P450 2B6enzyme
DB00503RitonavirCytochrome P450 2C8enzyme
DB00503RitonavirP-glycoprotein 1transporter
DB00503RitonavirMultidrug resistance-associated protein 1transporter
DB00503RitonavirCanalicular multispecific organic anion transporter 1transporter
DB00503RitonavirSolute carrier organic anion transporter family member 1A2transporter
DB00503RitonavirATP-binding cassette sub-family G member 2transporter
DB00503RitonavirSolute carrier organic anion transporter family member 1B1transporter
DB00503RitonavirCytochrome P450 1A2enzyme
DB00503RitonavirCytochrome P450 2E1enzyme
DB00503RitonavirNuclear receptor subfamily 1 group I member 2target
DB00503RitonavirSerum albumincarrier
DB00503RitonavirCytochrome P450 3A4enzyme
DB00503RitonavirCytochrome P450 3A5enzyme
DB00503RitonavirCytochrome P450 3A7enzyme
DB00503RitonavirCytochrome P450 3A43enzyme
DB00503RitonavirUDP-glucuronosyltransferase 1-1enzyme
DB00503RitonavirSolute carrier organic anion transporter family member 2B1transporter
DB00503RitonavirBile salt export pumptransporter
DB01110MiconazoleCytochrome P450 2C9enzyme
DB01110MiconazoleCytochrome P450 2D6enzyme
DB01110MiconazoleCytochrome P450 3A4enzyme
DB01110MiconazoleP-glycoprotein 1transporter
DB01110MiconazoleCytochrome P450 51target
DB01110MiconazoleNitric oxide synthase, endothelialtarget
DB01110MiconazoleNitric oxide synthase, inducibletarget
DB01110MiconazoleCalcium-activated potassium channel subunit alpha-1target
DB01110MiconazoleCalcium-activated potassium channel subunit beta-1target
DB01110MiconazoleCalcium-activated potassium channel subunit beta-2target
DB01110MiconazoleCalcium-activated potassium channel subunit beta-3target
DB01110MiconazoleCalcium-activated potassium channel subunit beta-4target
DB01110MiconazoleIntermediate conductance calcium-activated potassium channel protein 4target
DB01110MiconazoleSmall conductance calcium-activated potassium channel protein 1target
DB01110MiconazoleSmall conductance calcium-activated potassium channel protein 2target
DB01110MiconazoleSmall conductance calcium-activated potassium channel protein 3target
DB01110MiconazolePotassium voltage-gated channel subfamily H member 2target
DB01110MiconazolePotassium voltage-gated channel subfamily H member 6target
DB01110MiconazolePotassium voltage-gated channel subfamily H member 7target
DB01110MiconazoleCytochrome P450 11B1, mitochondrialenzyme
DB01110MiconazoleCytochrome P450 2A6enzyme
DB01110MiconazoleCytochrome P450 2B6enzyme
DB01110MiconazoleCytochrome P450 2C19enzyme
DB01110MiconazoleCytochrome P450 2E1enzyme
DB01110MiconazoleNuclear receptor subfamily 1 group I member 2target
DB01110MiconazoleLanosterol 14-alpha demethylaseenzyme
DB01110MiconazoleCytochrome P450 19A1enzyme
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-2target
DB00184NicotineNeuronal acetylcholine receptor subunit beta-2target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-7target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-4target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-10target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-9target
DB00184NicotineCytochrome P450 2A6enzyme
DB00184NicotineCytochrome P450 2E1enzyme
DB00184NicotineCytochrome P450 2A13enzyme
DB00184NicotineCytochrome P450 2B6enzyme
DB00184NicotineNeuronal acetylcholine receptor subunit beta-4target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-3target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-5target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-6target
DB00184NicotineNeuronal acetylcholine receptor subunit beta-3target
DB00184NicotineSolute carrier family 22 member 2transporter
DB00184NicotineSolute carrier family 22 member 1transporter
DB00184NicotineSolute carrier family 22 member 3transporter
DB00184NicotineSolute carrier family 22 member 5transporter
DB00184NicotineSolute carrier family 22 member 4transporter
DB00184NicotineCytochrome P450 1A1enzyme
DB00184NicotineCytochrome P450 1A2enzyme
DB00184NicotineCytochrome P450 2C19enzyme
DB00184NicotineCytochrome P450 2C8enzyme
DB00184NicotineCytochrome P450 2C9enzyme
DB00184NicotineCytochrome P450 2D6enzyme
DB00184NicotineCytochrome P450 3A4enzyme
DB00184NicotineAmine oxidase [flavin-containing] Aenzyme
DB00184NicotineAmine oxidase [flavin-containing] Benzyme
DB00184NicotineCytochrome P450 19A1target
DB00184NicotineCholine O-acetyltransferasetarget
DB00356ChlorzoxazoneCalcium-activated potassium channel subunit alpha-1target
DB00356ChlorzoxazoneCytochrome P450 2E1enzyme
DB00356ChlorzoxazoneCytochrome P450 1A2enzyme
DB00356ChlorzoxazoneCytochrome P450 2A6enzyme
DB00356ChlorzoxazoneCytochrome P450 1A1enzyme
DB00356ChlorzoxazoneCytochrome P450 2D6enzyme
DB00356ChlorzoxazoneCytochrome P450 3A4enzyme
DB01213FomepizoleAlcohol dehydrogenase 1Atarget
DB01213FomepizoleAlcohol dehydrogenase 1Btarget
DB01213FomepizoleAlcohol dehydrogenase 1Ctarget
DB01213FomepizoleCatalasetarget
DB01213FomepizoleCytochrome P450 2E1enzyme
DB01213FomepizoleCytochrome P450 2A6enzyme
DB00118AdemetionineGlycine N-methyltransferasetarget
DB00118AdemetionineS-adenosylmethionine decarboxylase proenzymetarget
DB00118AdemetionineS-adenosylmethionine synthase isoform type-2target
DB00118AdemetionineCystathionine beta-synthasetarget
DB00118AdemetionineS-adenosylmethionine synthase isoform type-1target
DB00118AdemetionineCytochrome P450 2E1enzyme
DB00118AdemetionineCatechol O-methyltransferasetarget
DB00118AdemetionineSpermidine synthaseenzyme
DB00118AdemetionineCap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1target
DB00118AdemetionineArsenite methyltransferasetarget
DB00818PropofolCytochrome P450 2B6enzyme
DB00818PropofolUDP-glucuronosyltransferase 1-1enzyme
DB00818PropofolUDP-glucuronosyltransferase 1-9enzyme
DB00818PropofolGamma-aminobutyric acid receptor subunit beta-2target
DB00818PropofolGamma-aminobutyric acid receptor subunit beta-3target
DB00818PropofolSerum albumincarrier
DB00818PropofolSodium channel protein type 4 subunit alphatarget
DB00818PropofolSodium channel protein type 2 subunit alphatarget
DB00818PropofolFatty-acid amide hydrolase 1enzyme
DB00818PropofolCytochrome P450 2C9enzyme
DB00818PropofolUDP-glucuronosyltransferase 1-8enzyme
DB00818PropofolCytochrome P450 2E1enzyme
DB00818PropofolCytochrome P450 1B1enzyme
DB00818PropofolCytochrome P450 1A1enzyme
DB00818PropofolCytochrome P450 1A2enzyme
DB00818PropofolCytochrome P450 2C18enzyme
DB00818PropofolCytochrome P450 2C19enzyme
DB00818PropofolCytochrome P450 2C8enzyme
DB00818PropofolUDP-glucuronosyltransferase 1-6enzyme
DB00818PropofolGABA-A receptor (anion channel)target
DB00969Alosetron5-hydroxytryptamine receptor 3Atarget
DB00969AlosetronCytochrome P450 1A2enzyme
DB00969AlosetronCytochrome P450 2C9enzyme
DB00969AlosetronCytochrome P450 3A4enzyme
DB00969AlosetronCytochrome P450 2E1enzyme
DB04794BifonazoleCytochrome P450 2B6target
DB04794BifonazoleCytochrome P450 51target
DB04794BifonazoleCytochrome P450 19A1enzyme
DB04794BifonazoleCytochrome P450 2E1enzyme
DB04794BifonazoleCytochrome P450 3A4enzyme
DB01558BromazepamGamma-aminobutyric acid receptor subunit alpha-2target
DB01558BromazepamGamma-aminobutyric acid receptor subunit alpha-1target
DB01558BromazepamGamma-aminobutyric acid receptor subunit alpha-3target
DB01558BromazepamGamma-aminobutyric acid receptor subunit alpha-4target
DB01558BromazepamGamma-aminobutyric acid receptor subunit alpha-5target
DB01558BromazepamGamma-aminobutyric acid receptor subunit alpha-6target
DB01558BromazepamGamma-aminobutyric acid receptor subunit beta-1target
DB01558BromazepamGamma-aminobutyric acid receptor subunit beta-2target
DB01558BromazepamGamma-aminobutyric acid receptor subunit beta-3target
DB01558BromazepamGamma-aminobutyric acid receptor subunit gamma-1target
DB01558BromazepamGamma-aminobutyric acid receptor subunit gamma-2target
DB01558BromazepamGamma-aminobutyric acid receptor subunit gamma-3target
DB01558BromazepamGamma-aminobutyric acid receptor subunit deltatarget
DB01558BromazepamGamma-aminobutyric acid receptor subunit epsilontarget
DB01558BromazepamGamma-aminobutyric acid receptor subunit pitarget
DB01558BromazepamGamma-aminobutyric acid receptor subunit rho-1target
DB01558BromazepamGamma-aminobutyric acid receptor subunit rho-2target
DB01558BromazepamGamma-aminobutyric acid receptor subunit thetatarget
DB01558BromazepamGamma-aminobutyric acid receptor subunit rho-3target
DB01558BromazepamCytochrome P450 1A2enzyme
DB01558BromazepamCytochrome P450 2C19enzyme
DB01558BromazepamCytochrome P450 2E1enzyme
DB00477ChlorpromazineDopamine D2 receptortarget
DB00477Chlorpromazine5-hydroxytryptamine receptor 2Atarget
DB00477ChlorpromazineCytochrome P450 2D6enzyme
DB00477ChlorpromazineCholinesteraseenzyme
DB00477ChlorpromazineCytochrome P450 1A2enzyme
DB00477ChlorpromazineSerum albumincarrier
DB00477ChlorpromazineP-glycoprotein 1transporter
DB00477ChlorpromazineDopamine D1 receptortarget
DB00477Chlorpromazine5-hydroxytryptamine receptor 1Atarget
DB00477ChlorpromazineAlpha-1A adrenergic receptortarget
DB00477ChlorpromazineAlpha-1B adrenergic receptortarget
DB00477ChlorpromazineCytochrome P450 2E1enzyme
DB00477ChlorpromazineCytochrome P450 3A4enzyme
DB00477ChlorpromazineHistamine H1 receptortarget
DB00477ChlorpromazinePotassium voltage-gated channel subfamily H member 2target
DB00477ChlorpromazineD(1) dopamine receptortarget
DB00477ChlorpromazineDopamine D3 receptortarget
DB00477ChlorpromazineDopamine D4 receptortarget
DB00477ChlorpromazineDopamine D5 receptortarget
DB00477Chlorpromazine5-hydroxytryptamine receptor 2Ctarget
DB00477Chlorpromazine5-hydroxytryptamine 2 receptortarget
DB00477ChlorpromazineAlpha-1 adrenergic receptorstarget
DB00477ChlorpromazineAlpha-2 adrenergic receptorstarget
DB00477ChlorpromazineMuscarinic acetylcholine receptor M1target
DB00477ChlorpromazineMuscarinic acetylcholine receptor M3target
DB00477ChlorpromazineSphingomyelin phosphodiesterasetarget
DB00477ChlorpromazineCalmodulintarget
DB00477Chlorpromazinealpha1-acid glycoproteintarget
DB00477Chlorpromazine5-hydroxytryptamine receptor 6target
DB00477Chlorpromazine5-hydroxytryptamine receptor 7target
DB00477ChlorpromazineHistamine H4 receptortarget
DB00477ChlorpromazineBile salt export pumptransporter
DB00501CimetidineHistamine H2 receptortarget
DB00501CimetidineCytochrome P450 1A2enzyme
DB00501CimetidineCytochrome P450 2D6enzyme
DB00501CimetidineCytochrome P450 2C19enzyme
DB00501CimetidineCytochrome P450 3A4enzyme
DB00501CimetidineCytochrome P450 3A5enzyme
DB00501CimetidineP-glycoprotein 1transporter
DB00501CimetidineSolute carrier family 22 member 2transporter
DB00501CimetidineSolute carrier family 22 member 1transporter
DB00501CimetidineSolute carrier family 22 member 3transporter
DB00501CimetidineSolute carrier family 22 member 5transporter
DB00501CimetidineSolute carrier family 22 member 6transporter
DB00501CimetidineSolute carrier family 22 member 8transporter
DB00501CimetidineMultidrug and toxin extrusion protein 1transporter
DB00501CimetidineSolute carrier family 22 member 4transporter
DB00501CimetidineSolute carrier family 22 member 11transporter
DB00501CimetidineSolute carrier family 22 member 7transporter
DB00501CimetidineCytochrome P450 11B1, mitochondrialenzyme
DB00501CimetidineCytochrome P450 2C8enzyme
DB00501CimetidineCytochrome P450 2C9enzyme
DB00501CimetidineCytochrome P450 2E1enzyme
DB00501CimetidineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00501CimetidineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00501CimetidineBile salt export pumptransporter
DB00501CimetidineMultidrug and toxin extrusion protein 2transporter
DB01151DesipramineMuscarinic acetylcholine receptor M1target
DB01151DesipramineSodium-dependent noradrenaline transportertarget
DB01151DesipramineBeta-2 adrenergic receptortarget
DB01151DesipramineMuscarinic acetylcholine receptor M2target
DB01151DesipramineSodium-dependent serotonin transportertarget
DB01151DesipramineHistamine H1 receptortarget
DB01151DesipramineBeta-1 adrenergic receptortarget
DB01151DesipramineCytochrome P450 2D6enzyme
DB01151DesipramineMuscarinic acetylcholine receptor M3target
DB01151DesipramineMuscarinic acetylcholine receptor M4target
DB01151DesipramineMuscarinic acetylcholine receptor M5target
DB01151DesipramineAlpha-1 adrenergic receptorstarget
DB01151Desipramine5-hydroxytryptamine receptor 2Atarget
DB01151DesipramineAlpha-1-acid glycoprotein 1carrier
DB01151DesipramineCytochrome P450 2B6enzyme
DB01151DesipramineCytochrome P450 3A4enzyme
DB01151DesipramineSolute carrier family 22 member 2transporter
DB01151DesipramineSolute carrier family 22 member 1transporter
DB01151DesipramineSolute carrier family 22 member 3transporter
DB01151DesipramineSolute carrier family 22 member 5transporter
DB01151DesipramineP-glycoprotein 1transporter
DB01151DesipramineSolute carrier family 22 member 4transporter
DB01151DesipramineCytochrome P450 1A2enzyme
DB01151DesipramineCytochrome P450 2E1enzyme
DB01151DesipramineSphingomyelin phosphodiesterasetarget
DB01151Desipramine5-hydroxytryptamine receptor 1Atarget
DB01151Desipramine5-hydroxytryptamine receptor 2Ctarget
DB01151DesipramineDopamine D2 receptortarget
DB01151DesipramineAlpha-2 adrenergic receptorstarget
DB00586DiclofenacProstaglandin G/H synthase 1target
DB00586DiclofenacProstaglandin G/H synthase 2target
DB00586DiclofenacTransthyretincarrier
DB00586DiclofenacCytochrome P450 2C9enzyme
DB00586DiclofenacCytochrome P450 2C19enzyme
DB00586DiclofenacCytochrome P450 1A2enzyme
DB00586DiclofenacCytochrome P450 2C8enzyme
DB00586DiclofenacSerum albumincarrier
DB00586DiclofenacMultidrug resistance-associated protein 4transporter
DB00586DiclofenacMultidrug resistance-associated protein 1transporter
DB00586DiclofenacSolute carrier family 22 member 6transporter
DB00586DiclofenacSolute carrier family 22 member 8transporter
DB00586DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DB00586DiclofenacSolute carrier family 22 member 11transporter
DB00586DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DB00586DiclofenacCytochrome P450 3A4enzyme
DB00586DiclofenacCytochrome P450 2B6enzyme
DB00586DiclofenacCytochrome P450 2C18enzyme
DB00586DiclofenacCytochrome P450 2E1enzyme
DB00586DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DB00586DiclofenacBile salt export pumptransporter
DB00586DiclofenacUDP-glucuronosyltransferase 1-3enzyme
DB00586DiclofenacUDP-glucuronosyltransferase 1-9enzyme
DB00586DiclofenacUDP-glucuronosyltransferase 2B4enzyme
DB00586DiclofenacArachidonate 5-lipoxygenaseenzyme
DB00586DiclofenacSodium channel protein type 4 subunit alphatransporter
DB00586DiclofenacAcid-sensing ion channel 1transporter
DB00586DiclofenacPotassium voltage-gated channel subfamily KQT member 2transporter
DB00586DiclofenacPotassium voltage-gated channel subfamily KQT member 3transporter
DB00586DiclofenacPhospholipase A2, membrane associatedenzyme
DB01628EtoricoxibProstaglandin G/H synthase 2target
DB01628EtoricoxibCytochrome P450 3A4enzyme
DB01628EtoricoxibCytochrome P450 2C9enzyme
DB01628EtoricoxibCytochrome P450 2D6enzyme
DB01628EtoricoxibCytochrome P450 1A2enzyme
DB01628EtoricoxibCytochrome P450 2C19enzyme
DB01628EtoricoxibCytochrome P450 2E1enzyme
DB00623FluphenazineDopamine D2 receptortarget
DB00623FluphenazineCalmodulintarget
DB00623FluphenazineDopamine D1 receptortarget
DB00623FluphenazineCytochrome P450 2D6enzyme
DB00623FluphenazineP-glycoprotein 1transporter
DB00623FluphenazineCytochrome P450 2E1enzyme
DB00623FluphenazineAndrogen receptortarget
DB00623Fluphenazine5-hydroxytryptamine receptor 2Atarget
DB00623Fluphenazine5-hydroxytryptamine receptor 2Ctarget
DB00690FlurazepamGamma-aminobutyric acid receptor subunit alpha-1target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit beta-1target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit beta-3target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit alpha-5target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit alpha-3target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit alpha-2target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit beta-2target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit alpha-4target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit alpha-6target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit gamma-1target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit gamma-2target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit gamma-3target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit deltatarget
DB00690FlurazepamGamma-aminobutyric acid receptor subunit epsilontarget
DB00690FlurazepamGamma-aminobutyric acid receptor subunit pitarget
DB00690FlurazepamGamma-aminobutyric acid receptor subunit rho-2target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit thetatarget
DB00690FlurazepamGamma-aminobutyric acid receptor subunit rho-1target
DB00690FlurazepamCytochrome P450 3A4enzyme
DB00690FlurazepamGamma-aminobutyric acid receptor subunit rho-3target
DB00690FlurazepamP-glycoprotein 1transporter
DB00690FlurazepamCytochrome P450 2E1enzyme
DB00690FlurazepamCytochrome P450 2A6enzyme
DB00690FlurazepamSolute carrier family 22 member 2transporter
DB00458ImipramineSodium-dependent noradrenaline transportertarget
DB00458ImipramineSodium-dependent serotonin transportertarget
DB00458ImipramineCytochrome P450 1A2enzyme
DB00458ImipramineCytochrome P450 2C19enzyme
DB00458ImipramineCytochrome P450 2D6enzyme
DB00458ImipramineHistamine H1 receptortarget
DB00458ImipramineAlpha-1A adrenergic receptortarget
DB00458Imipramine5-hydroxytryptamine receptor 2Atarget
DB00458ImipramineMuscarinic acetylcholine receptor M1target
DB00458ImipramineMuscarinic acetylcholine receptor M2target
DB00458ImipramineMuscarinic acetylcholine receptor M3target
DB00458ImipramineMuscarinic acetylcholine receptor M4target
DB00458ImipramineMuscarinic acetylcholine receptor M5target
DB00458ImipraminePotassium voltage-gated channel subfamily D member 2target
DB00458ImipraminePotassium voltage-gated channel subfamily D member 3target
DB00458ImipramineAlpha-1D adrenergic receptortarget
DB00458ImipramineAlpha-1-acid glycoprotein 1carrier
DB00458ImipramineSolute carrier family 22 member 2transporter
DB00458ImipramineSolute carrier family 22 member 3transporter
DB00458ImipramineP-glycoprotein 1transporter
DB00458ImipramineSolute carrier family 22 member 4transporter
DB00458ImipramineCytochrome P450 3A4enzyme
DB00458ImipramineCytochrome P450 2B6enzyme
DB00458ImipramineCytochrome P450 2C18enzyme
DB00458ImipramineCytochrome P450 2E1enzyme
DB00458ImipramineCytochrome P450 3A7enzyme
DB00458Imipramine5-hydroxytryptamine receptor 2Ctarget
DB00458ImipramineAlpha-1B adrenergic receptortarget
DB00458Imipramine5-hydroxytryptamine receptor 7target
DB00458ImipramineD(1) dopamine receptortarget
DB00458ImipramineDopamine D2 receptortarget
DB00458ImipraminePotassium voltage-gated channel subfamily H member 2target
DB00458ImipramineSodium-dependent dopamine transportertarget
DB00458Imipramine5-hydroxytryptamine receptor 1Atarget
DB00458Imipramine5-hydroxytryptamine receptor 6target
DB00458ImipraminePotassium voltage-gated channel subfamily H member 1target
DB00458ImipramineSerum albumincarrier
DB00458ImipramineAlpha-1-acid glycoprotein 2target
DB00883Isosorbide dinitrateAtrial natriuretic peptide receptor 1target
DB00883Isosorbide dinitrateCytochrome P450 2E1enzyme
DB01167ItraconazoleLanosterol 14-alpha demethylasetarget
DB01167ItraconazoleLanosterol 14-alpha demethylasetarget
DB01167ItraconazoleCytochrome P450 3A4enzyme
DB01167ItraconazoleCytochrome P450 3A5enzyme
DB01167ItraconazoleCytochrome P450 3A7enzyme
DB01167ItraconazoleCytochrome P450 2B6enzyme
DB01167ItraconazoleP-glycoprotein 1transporter
DB01167ItraconazoleCytochrome P450 1A1enzyme
DB01167ItraconazoleCytochrome P450 2E1enzyme
DB01167ItraconazoleSolute carrier organic anion transporter family member 2B1transporter
DB01011MetyraponeCamphor 5-monooxygenasetarget
DB01011MetyraponeCytochrome P450 11B2, mitochondrialenzyme
DB01011MetyraponeCytochrome P450 2A6enzyme
DB01011MetyraponeCytochrome P450 3A4enzyme
DB01011MetyraponeCanalicular multispecific organic anion transporter 2transporter
DB01011MetyraponeCytochrome P450 11B1, mitochondrialtarget
DB01011MetyraponeCytochrome P450 11B1, mitochondrialenzyme
DB01011MetyraponeCytochrome P450 2E1enzyme
DB02701NicotinamideNAD-dependent protein deacylase sirtuin-5, mitochondrialtarget
DB02701NicotinamideADP-ribosyl cyclase 2target
DB02701NicotinamideExotoxin Atarget
DB02701NicotinamideL-lactate dehydrogenase A chaintarget
DB02701NicotinamidePoly [ADP-ribose] polymerase 1target
DB02701NicotinamideCytochrome P450 2D6enzyme
DB02701NicotinamideCytochrome P450 2E1enzyme
DB02701NicotinamideCytochrome P450 3A4enzyme
DB00540NortriptylineSodium-dependent serotonin transportertarget
DB00540NortriptylineSodium-dependent noradrenaline transportertarget
DB00540NortriptylineCytochrome P450 1A2enzyme
DB00540NortriptylineCytochrome P450 2D6enzyme
DB00540NortriptylineSerum albumincarrier
DB00540NortriptylineAlpha-1-acid glycoprotein 1carrier
DB00540NortriptylineHistamine H1 receptortarget
DB00540NortriptylineMuscarinic acetylcholine receptor M1target
DB00540NortriptylineMuscarinic acetylcholine receptor M2target
DB00540NortriptylineMuscarinic acetylcholine receptor M3target
DB00540NortriptylineMuscarinic acetylcholine receptor M4target
DB00540NortriptylineMuscarinic acetylcholine receptor M5target
DB00540Nortriptyline5-hydroxytryptamine receptor 2Atarget
DB00540NortriptylineAlpha-1A adrenergic receptortarget
DB00540Nortriptyline5-hydroxytryptamine receptor 1Atarget
DB00540NortriptylineCytochrome P450 3A4enzyme
DB00540NortriptylineCytochrome P450 3A5enzyme
DB00540NortriptylineAlpha-1D adrenergic receptortarget
DB00540NortriptylineCytochrome P450 2C19enzyme
DB00540NortriptylineProstaglandin G/H synthase 1enzyme
DB00540NortriptylineCytochrome P450 2E1enzyme
DB00540Nortriptyline5-hydroxytryptamine receptor 2Ctarget
DB00540Nortriptyline5-hydroxytryptamine receptor 6target
DB00540NortriptylineAlpha-1B adrenergic receptortarget
DB00540NortriptylineAlpha-2 adrenergic receptorstarget
DB00540NortriptylineBeta adrenergic receptortarget
DB00540NortriptylineDopamine D2 receptortarget
DB00540NortriptylineSigma receptortarget
DB00540Nortriptyline5-hydroxytryptamine receptor 1Ctarget
DB01037SelegilineAmine oxidase [flavin-containing] Btarget
DB01037SelegilineCytochrome P450 2B6enzyme
DB01037SelegilineAmine oxidase [flavin-containing] Atarget
DB01037SelegilineCytochrome P450 2A6enzyme
DB01037SelegilineCytochrome P450 3A4enzyme
DB01037SelegilineP-glycoprotein 1transporter
DB01037SelegilineCytochrome P450 1A2enzyme
DB01037SelegilineCytochrome P450 2C19enzyme
DB01037SelegilineCytochrome P450 2C8enzyme
DB01037SelegilineCytochrome P450 2C9enzyme
DB01037SelegilineCytochrome P450 2D6enzyme
DB01037SelegilineCytochrome P450 2E1enzyme
DB00203SildenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00203SildenafilCytochrome P450 2C9enzyme
DB00203SildenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00203SildenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00203SildenafilCytochrome P450 3A4enzyme
DB00203SildenafilCytochrome P450 3A5enzyme
DB00203SildenafilCytochrome P450 3A7enzyme
DB00203SildenafilMultidrug resistance-associated protein 4transporter
DB00203SildenafilMultidrug resistance-associated protein 5transporter
DB00203SildenafilMultidrug resistance-associated protein 7transporter
DB00203SildenafilCytochrome P450 2C19enzyme
DB00203SildenafilCytochrome P450 2D6enzyme
DB00203SildenafilCytochrome P450 2E1enzyme
DB00203SildenafilSolute carrier organic anion transporter family member 1B1transporter
DB00203SildenafilP-glycoprotein 1transporter
DB00259SulfanilamideDihydropteroate synthasetarget
DB00259SulfanilamideCytochrome P450 2C19enzyme
DB00259SulfanilamideCytochrome P450 2D6enzyme
DB00259SulfanilamideCytochrome P450 2E1enzyme
DB00259SulfanilamideCytochrome P450 3A4enzyme
DB01079Tegaserod5-hydroxytryptamine receptor 4target
DB01079Tegaserod5-hydroxytryptamine receptor 2Btarget
DB01079Tegaserod5-hydroxytryptamine receptor 2Ctarget
DB01079Tegaserod5-hydroxytryptamine receptor 2Atarget
DB01079TegaserodSodium-dependent serotonin transportertransporter
DB01079TegaserodCytochrome P450 1A2enzyme
DB01079TegaserodCytochrome P450 2C8enzyme
DB01079TegaserodCytochrome P450 2D6enzyme
DB01079TegaserodCytochrome P450 2E1enzyme
DB01079TegaserodATP-binding cassette sub-family G member 2transporter
DB01079TegaserodP-glycoprotein 1transporter
DB00763MethimazoleThyroid peroxidasetarget
DB00763MethimazoleCytochrome P450 1A2enzyme
DB00763MethimazoleCytochrome P450 2A6enzyme
DB00763MethimazoleCytochrome P450 2B6enzyme
DB00763MethimazoleCytochrome P450 2C19enzyme
DB00763MethimazoleCytochrome P450 2C9enzyme
DB00763MethimazoleCytochrome P450 2D6enzyme
DB00763MethimazoleCytochrome P450 2E1enzyme
DB00763MethimazoleCytochrome P450 3A4enzyme
DB00763MethimazoleDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00679ThioridazineAlpha-1A adrenergic receptortarget
DB00679ThioridazineDopamine D2 receptortarget
DB00679Thioridazine5-hydroxytryptamine receptor 2Atarget
DB00679ThioridazineDopamine D1 receptortarget
DB00679ThioridazineCytochrome P450 2C19enzyme
DB00679ThioridazineCytochrome P450 2D6enzyme
DB00679ThioridazineAlpha-1B adrenergic receptortarget
DB00679ThioridazinePotassium voltage-gated channel subfamily H member 2target
DB00679ThioridazineCytochrome P450 2E1enzyme
DB01007TioconazoleLanosterol 14-alpha demethylasetarget
DB01007TioconazoleCytochrome P450 19A1enzyme
DB01007TioconazoleCytochrome P450 2C19enzyme
DB01007TioconazoleCytochrome P450 2E1enzyme
DB01007TioconazoleCytochrome P450 3A4enzyme
DB01007TioconazoleCytochrome P450 51target
DB00752TranylcypromineAmine oxidase [flavin-containing] Btarget
DB00752TranylcypromineAmine oxidase [flavin-containing] Atarget
DB00752TranylcypromineCytochrome P450 2C19enzyme
DB00752TranylcypromineCytochrome P450 2A6enzyme
DB00752TranylcypromineCytochrome P450 2D6enzyme
DB00752TranylcypromineCytochrome P450 1A2enzyme
DB00752TranylcypromineCytochrome P450 2C9enzyme
DB00752TranylcypromineCytochrome P450 2E1enzyme
DB01586Ursodeoxycholic acidAldo-keto reductase family 1 member C2target
DB01586Ursodeoxycholic acidBile salt export pumptransporter
DB01586Ursodeoxycholic acidSolute carrier organic anion transporter family member 1A2transporter
DB01586Ursodeoxycholic acidCanalicular multispecific organic anion transporter 1transporter
DB01586Ursodeoxycholic acidMultidrug resistance-associated protein 4transporter
DB01586Ursodeoxycholic acidIleal sodium/bile acid cotransportertransporter
DB01586Ursodeoxycholic acidSodium/bile acid cotransportertransporter
DB01586Ursodeoxycholic acidCytochrome P450 2E1enzyme
DB01586Ursodeoxycholic acidBile acid receptortarget
DB00549ZafirlukastCysteinyl leukotriene receptor 1target
DB00549ZafirlukastCytochrome P450 2C9enzyme
DB00549ZafirlukastCytochrome P450 2C8enzyme
DB00549ZafirlukastProstaglandin G/H synthase 1enzyme
DB00549ZafirlukastCytochrome P450 3A4enzyme
DB00549ZafirlukastCytochrome P450 1A2enzyme
DB00549ZafirlukastCytochrome P450 2C19enzyme
DB00549ZafirlukastCytochrome P450 2E1enzyme
DB00549ZafirlukastATP-binding cassette sub-family G member 2transporter
DB00255DiethylstilbestrolEstrogen receptor alphatarget
DB00255DiethylstilbestrolEstrogen-related receptor gammatarget
DB00255DiethylstilbestrolTransthyretincarrier
DB00255DiethylstilbestrolCatechol O-methyltransferaseenzyme
DB00255DiethylstilbestrolCytochrome P450 19A1enzyme
DB00255DiethylstilbestrolATP-binding cassette sub-family G member 2transporter
DB00255DiethylstilbestrolP-glycoprotein 1transporter
DB00255DiethylstilbestrolEstrogen receptor betatarget
DB00255DiethylstilbestrolCytochrome P450 3A4enzyme
DB00255DiethylstilbestrolCytochrome P450 2C8enzyme
DB00255DiethylstilbestrolCytochrome P450 2C9enzyme
DB00255DiethylstilbestrolCytochrome P450 2E1enzyme
DB00255DiethylstilbestrolSteroid hormone receptor ERR1target
DB00255DiethylstilbestrolSteroid hormone receptor ERR2target
DB00255DiethylstilbestrolNuclear receptor coactivator 2target
DB00255DiethylstilbestrolNuclear receptor subfamily 1 group I member 2target
DB00255DiethylstilbestrolAndrogen receptortarget
DB00255DiethylstilbestrolSex hormone-binding globulintarget
DB00255DiethylstilbestrolSolute carrier organic anion transporter family member 1B1transporter
DB00255DiethylstilbestrolSolute carrier organic anion transporter family member 2B1transporter
DB00255DiethylstilbestrolBile salt export pumptransporter
DB06370IndisulamCytochrome P450 2C9enzyme
DB06370IndisulamCytochrome P450 3A4enzyme
DB06370IndisulamCytochrome P450 2E1enzyme
DB06370IndisulamCytochrome P450 2D6enzyme
DB00041AldesleukinInterleukin-2 receptor subunit betatarget
DB00041AldesleukinInterleukin-2 receptor subunit alphatarget
DB00041AldesleukinCytokine receptor common subunit gammatarget
DB00041AldesleukinProstaglandin G/H synthase 2enzyme
DB00041AldesleukinCytosolic phospholipase A2enzyme
DB00041AldesleukinCytochrome P450 3A4enzyme
DB00041AldesleukinXanthine dehydrogenase/oxidaseenzyme
DB00041AldesleukinCytochrome P450 2E1enzyme
DB01068ClonazepamTranslocator proteintarget
DB01068ClonazepamCytochrome P450 3A4enzyme
DB01068ClonazepamSerum albumincarrier
DB01068ClonazepamCytochrome P450 2E1enzyme
DB01068ClonazepamArylamine N-acetyltransferase 2enzyme
DB01068ClonazepamGABA-A receptor (anion channel)target
DB01068ClonazepamNuclear receptor subfamily 1 group I member 2target
DB00829DiazepamTranslocator proteintarget
DB00829DiazepamGamma-aminobutyric acid receptor subunit alpha-1target
DB00829DiazepamGamma-aminobutyric acid receptor subunit alpha-2target
DB00829DiazepamGamma-aminobutyric acid receptor subunit alpha-3target
DB00829DiazepamCytochrome P450 3A4enzyme
DB00829DiazepamSerum albumincarrier
DB00829DiazepamCytochrome P450 2C9enzyme
DB00829DiazepamCytochrome P450 2C19enzyme
DB00829DiazepamCytochrome P450 3A5enzyme
DB00829DiazepamCytochrome P450 3A7enzyme
DB00829DiazepamGamma-aminobutyric acid receptor subunit alpha-5target
DB00829DiazepamGamma-aminobutyric acid receptor subunit beta-1target
DB00829DiazepamGamma-aminobutyric acid receptor subunit beta-2target
DB00829DiazepamGamma-aminobutyric acid receptor subunit beta-3target
DB00829DiazepamGamma-aminobutyric acid receptor subunit gamma-1target
DB00829DiazepamGamma-aminobutyric acid receptor subunit gamma-2target
DB00829DiazepamGamma-aminobutyric acid receptor subunit gamma-3target
DB00829DiazepamGamma-aminobutyric acid receptor subunit deltatarget
DB00829DiazepamGamma-aminobutyric acid receptor subunit epsilontarget
DB00829DiazepamGamma-aminobutyric acid receptor subunit pitarget
DB00829DiazepamGamma-aminobutyric acid receptor subunit rho-1target
DB00829DiazepamGamma-aminobutyric acid receptor subunit rho-2target
DB00829DiazepamGamma-aminobutyric acid receptor subunit rho-3target
DB00829DiazepamGamma-aminobutyric acid receptor subunit thetatarget
DB00829DiazepamP-glycoprotein 1transporter
DB00829DiazepamCytochrome P450 2B6enzyme
DB00829DiazepamProstaglandin G/H synthase 1enzyme
DB00829DiazepamCytochrome P450 2C18enzyme
DB00829DiazepamCytochrome P450 2C8enzyme
DB00829DiazepamCytochrome P450 2E1enzyme
DB00829DiazepamGABA-A receptor (anion channel)target
DB01544FlunitrazepamGamma-aminobutyric acid receptor subunit alpha-2target
DB01544FlunitrazepamGamma-aminobutyric acid receptor subunit alpha-4target
DB01544FlunitrazepamGamma-aminobutyric acid receptor subunit alpha-5target
DB01544FlunitrazepamGamma-aminobutyric acid receptor subunit alpha-6target
DB01544FlunitrazepamGamma-aminobutyric acid receptor subunit alpha-3target
DB01544FlunitrazepamTranslocator proteintarget
DB01544FlunitrazepamCytochrome P450 2C19enzyme
DB01544FlunitrazepamUDP-glucuronosyltransferase 2B7enzyme
DB01544FlunitrazepamCytochrome P450 2A6enzyme
DB01544FlunitrazepamCytochrome P450 2B6enzyme
DB01544FlunitrazepamCytochrome P450 2C9enzyme
DB01544FlunitrazepamCytochrome P450 3A4enzyme
DB01544FlunitrazepamCytochrome P450 2E1enzyme
DB01544FlunitrazepamUDP-glucuronosyltransferase 1-1enzyme
DB01544FlunitrazepamUDP-glucuronosyltransferase 1-3enzyme
DB01544FlunitrazepamGamma-aminobutyric acid receptor subunit alpha-1target
DB01544FlunitrazepamGamma-aminobutyric acid receptor subunit beta-3target
DB01544FlunitrazepamGamma-aminobutyric acid receptor subunit gamma-2target
DB01595NitrazepamGamma-aminobutyric acid receptor subunit alpha-1target
DB01595NitrazepamSodium channel protein type 1 subunit alphatarget
DB01595NitrazepamGamma-aminobutyric acid receptor subunit alpha-2target
DB01595NitrazepamGamma-aminobutyric acid receptor subunit alpha-3target
DB01595NitrazepamGamma-aminobutyric acid receptor subunit alpha-4target
DB01595NitrazepamGamma-aminobutyric acid receptor subunit alpha-5target
DB01595NitrazepamGamma-aminobutyric acid receptor subunit alpha-6target
DB01595NitrazepamGamma-aminobutyric acid receptor subunit beta-1target
DB01595NitrazepamGamma-aminobutyric acid receptor subunit beta-2target
DB01595NitrazepamGamma-aminobutyric acid receptor subunit beta-3target
DB01595NitrazepamGamma-aminobutyric acid receptor subunit gamma-1target
DB01595NitrazepamGamma-aminobutyric acid receptor subunit gamma-2target
DB01595NitrazepamGamma-aminobutyric acid receptor subunit gamma-3target
DB01595NitrazepamGamma-aminobutyric acid receptor subunit deltatarget
DB01595NitrazepamGamma-aminobutyric acid receptor subunit epsilontarget
DB01595NitrazepamGamma-aminobutyric acid receptor subunit pitarget
DB01595NitrazepamGamma-aminobutyric acid receptor subunit rho-1target
DB01595NitrazepamGamma-aminobutyric acid receptor subunit rho-2target
DB01595NitrazepamGamma-aminobutyric acid receptor subunit rho-3target
DB01595NitrazepamGamma-aminobutyric acid receptor subunit thetatarget
DB01595NitrazepamCytochrome P450 3A4enzyme
DB01595NitrazepamCytochrome P450 2E1enzyme
DB08846Ellagic acidSolute carrier family 22 member 6transporter
DB08846Ellagic acidSolute carrier family 22 member 11transporter
DB08846Ellagic acidCytochrome P450 1A1enzyme
DB08846Ellagic acidCytochrome P450 2E1enzyme
DB08846Ellagic acidCarbonic anhydrase 1target
DB08846Ellagic acidCarbonic anhydrase 2target
DB08846Ellagic acidCarbonic anhydrase 3target
DB08846Ellagic acidCarbonic anhydrase 4target
DB08846Ellagic acidCarbonic anhydrase 5A, mitochondrialtarget
DB08846Ellagic acidCarbonic anhydrase 5B, mitochondrialtarget
DB08846Ellagic acidCarbonic anhydrase 6target
DB08846Ellagic acidCarbonic anhydrase 7target
DB08846Ellagic acidCarbonic anhydrase 9target
DB08846Ellagic acidCarbonic anhydrase 12target
DB08846Ellagic acidCarbonic anhydrase 14target
DB08846Ellagic acidCasein kinase II subunit alphatarget
DB08846Ellagic acidcAMP-dependent protein kinase catalytic subunit alphatarget
DB08846Ellagic acidProtein kinase C alpha typetarget
DB08846Ellagic acidProtein kinase C beta typetarget
DB08846Ellagic acidTyrosine-protein kinase SYKtarget
DB08846Ellagic acidSqualene monooxygenasetarget
DB11994DiacereinOxysterols receptor LXR-alphatarget
DB11994DiacereinOxysterols receptor LXR-betatarget
DB11994DiacereinArylamine N-acetyltransferasetarget
DB11994DiacereinArachidonate 5-lipoxygenasetarget
DB11994DiacereinCytochrome P450 1A2target
DB11994DiacereinCytochrome P450 3A Subfamilytarget
DB11994DiacereinCytochrome P450 2E1target
DB11994DiacereinCytochrome P450 2C9target
DB11994DiacereinCytochrome P450 2D6target
DB06654SafinamideAmine oxidase [flavin-containing] Btarget
DB06654SafinamideAmine oxidase [flavin-containing] Aenzyme
DB06654SafinamideATP-binding cassette sub-family G member 2transporter
DB06654SafinamideSolute carrier organic anion transporter family member 3A1transporter
DB06654SafinamideCytochrome P450 3A4enzyme
DB06654SafinamideCytochrome P450 1A1enzyme
DB06654SafinamideCytochrome P450 1A2enzyme
DB06654SafinamideCytochrome P450 2B6enzyme
DB06654SafinamideCytochrome P450 2C9enzyme
DB06654SafinamideCytochrome P450 2D6enzyme
DB06654SafinamideCytochrome P450 2C19enzyme
DB06654SafinamideCytochrome P450 2E1enzyme
DB06654SafinamideCytochrome P450 3A5enzyme
DB00972AzelastineHistamine H1 receptortarget
DB00972AzelastineCytochrome P450 1A2enzyme
DB00972AzelastineCytochrome P450 2D6enzyme
DB00972AzelastineCytochrome P450 3A4enzyme
DB00972AzelastineCytochrome P450 2C19enzyme
DB00972AzelastineCytochrome P450 1A1enzyme
DB00972AzelastineCytochrome P450 3A5enzyme
DB00972AzelastineCytochrome P450 2C9enzyme
DB00972AzelastineCytochrome P450 2C8enzyme
DB00972AzelastineP-glycoprotein 1transporter
DB00972AzelastineCytochrome P450 2A6enzyme
DB00972AzelastineCytochrome P450 2E1enzyme
DB00972AzelastineHistamine H2 receptortarget
DB00972AzelastinePhospholipase A2target
DB00972AzelastineLeukotriene C4 synthasetarget
DB00972AzelastineCytochrome P450 2B6enzyme
DB01191DexfenfluramineSodium-dependent serotonin transportertarget
DB01191Dexfenfluramine5-hydroxytryptamine receptor 2Ctarget
DB01191DexfenfluramineCytochrome P450 2D6enzyme
DB01191DexfenfluramineCytochrome P450 1A2enzyme
DB01191DexfenfluramineCytochrome P450 2E1enzyme
DB01403MethotrimeprazineDopamine D3 receptortarget
DB01403MethotrimeprazineHistamine H1 receptortarget
DB01403MethotrimeprazineMuscarinic acetylcholine receptor M1target
DB01403MethotrimeprazineMuscarinic acetylcholine receptor M2target
DB01403MethotrimeprazineMuscarinic acetylcholine receptor M3target
DB01403MethotrimeprazineMuscarinic acetylcholine receptor M4target
DB01403MethotrimeprazineMuscarinic acetylcholine receptor M5target
DB01403MethotrimeprazineAlpha-1A adrenergic receptortarget
DB01403MethotrimeprazineAlpha-1B adrenergic receptortarget
DB01403MethotrimeprazineAlpha-1D adrenergic receptortarget
DB01403MethotrimeprazineCytochrome P450 2D6enzyme
DB01403MethotrimeprazineDopamine D2 receptortarget
DB01403MethotrimeprazineDopamine D1 receptortarget
DB01403MethotrimeprazineDopamine D5 receptortarget
DB01403MethotrimeprazineDopamine D4 receptortarget
DB01403MethotrimeprazineAlpha-2A adrenergic receptortarget
DB01403MethotrimeprazineAlpha-2B adrenergic receptortarget
DB01403MethotrimeprazineAlpha-2C adrenergic receptortarget
DB01403Methotrimeprazine5-hydroxytryptamine receptor 2Atarget
DB01403Methotrimeprazine5-hydroxytryptamine receptor 2Ctarget
DB01403MethotrimeprazineCytochrome P450 2E1enzyme
DB09328VayarinCytochrome P450 2E1enzyme
DB09328VayarinFatty acid desaturase 1enzyme
DB09328VayarinElongation of very long chain fatty acids protein 4enzyme
DB09328VayarinPeroxisomal acyl-coenzyme A oxidase 1enzyme
DB02520DitiocarbCytochrome P450 2E1enzyme
DB02520DitiocarbCytochrome P450 3A4enzyme
DB02520DitiocarbCytochrome P450 3A5enzyme
DB00627NiacinHydroxycarboxylic acid receptor 2target
DB00627NiacinNicotinamide N-methyltransferasetarget
DB00627NiacinNicotinate-nucleotide pyrophosphorylase [carboxylating]target
DB00627NiacinHydroxycarboxylic acid receptor 3target
DB00627NiacinSolute carrier family 22 member 5transporter
DB00627NiacinSolute carrier organic anion transporter family member 2B1transporter
DB00627NiacinMonocarboxylate transporter 1transporter
DB00627NiacinCytochrome P450 2D6enzyme
DB00627NiacinSodium-coupled monocarboxylate transporter 1transporter
DB00627NiacinMonocarboxylate transporter 4transporter
DB00627NiacinThyroxine-binding globulincarrier
DB00627NiacinCytochrome P450 3A4enzyme
DB00627NiacinCytochrome P450 2E1enzyme
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 1target
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 2Dtarget
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 3Btarget
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 3Atarget
DB01173OrphenadrineHistamine H1 receptortarget
DB01173OrphenadrineCytochrome P450 2B6enzyme
DB01173OrphenadrineCytochrome P450 2E1enzyme
DB01173OrphenadrineCytochrome P450 3A4enzyme
DB01173OrphenadrineSodium-dependent noradrenaline transportertarget
DB01173OrphenadrineSodium channel protein type 10 subunit alphatarget
DB01173OrphenadrineCytochrome P450 1A2enzyme
DB01173OrphenadrineCytochrome P450 2D6enzyme