| DB00439 | Cerivastatin | A statin (or HMG CoA reductase inhibitor) used with dietary changes to decrease lipid levels and reduce the risk of cardiovascular events. |
| DB00682 | Warfarin | A vitamin K antagonist used to treat venous thromboembolism, pulmonary embolism, thromboembolism with atrial fibrillation, thromboembolism with cardiac valve replacement, and thromboembolic events post myocardial infarction. |
| DB01259 | Lapatinib | An antineoplastic agent and tyrosine kinase inhibitor used for the treatment of advanced or metastatic HER-negative breast cancer in patients who received prior chemotherapeutic treatments. |
| DB00481 | Raloxifene | A selective estrogen receptor modulator that is used to prevent and treat osteoporosis and reduce the risk of invasive breast cancer in high-risk postmenopausal women. |
| DB04216 | Quercetin | Quercetin is a flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin. |
| DB00977 | Ethinylestradiol | An estradiol used as a contraceptive. |
| DB00907 | Cocaine | An ester local anesthetic used during diagnostic procedures and surgeries in or through the nasal cavities. |
| DB01394 | Colchicine | An alkaloid used in the symptomatic relief of pain in attacks of gout and to treat the inflammatory symptoms of Familial Mediterranean Fever (FMF). |
| DB00951 | Isoniazid | An antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis. |
| DB00814 | Meloxicam | An NSAID used to treat osteoarthritis in adults, rheumatoid arthritis in adults, and juvenile rheumatoid arthritis in pediatrics. |
| DB00916 | Metronidazole | A nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections. |
| DB00665 | Nilutamide | An antineoplastic hormone used to treat prostate cancer. |
| DB00780 | Phenelzine | A monoamine oxidase inhibitor used to treat atypical, nonendogenous, or neurotic depression. |
| DB00554 | Piroxicam | An NSAID used to treat the symptoms of osteoarthritis and rheumatoid arthritis. |
| DB06729 | Sulfaphenazole | For the treatment bacterial infections. |
| DB00342 | Terfenadine | For the treatment of allergic rhinitis, hay fever, and allergic skin disorders. |
| DB00897 | Triazolam | A benzodiazepine used for short term treatment of insomnia. |
| DB00313 | Valproic acid | An anticonvulsant used to control complex partial seizures and both simple and complex absence seizures. |
| DB00255 | Diethylstilbestrol | Used in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery. |
| DB08828 | Vismodegib | A hedgehog pathway inhibitor used to treat patients with locally advanced or metastatic basal cell carcinoma. |
| DB08896 | Regorafenib | A kinase inhibitor used to treat patients with metastatic colorectal cancer, unresectable, locally advanced, or metastatic gastrointestinal stromal tumors, and hepatocellular carcinoma. |
| DB09280 | Lumacaftor | A protein chaperone used in combination with ivacaftor for the treatment of cystic fibrosis in patients who are homozygous for the F508del mutation in the CFTR gene. |
| DB06595 | Midostaurin | An antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL). |
| DB13874 | Enasidenib | An isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation. |
| DB12070 | Letermovir | An antiviral medication used to treat CMV infections and disease in adult CMV-seropositive recipients of an allogeneic hematopoietic stem cell transplant (HSCT). |
| DB06616 | Bosutinib | An antineoplastic agent used for the treatment of chronic, accelerated, or blast phase Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML) in adults with inadequate clinical response to other treatments. |
| DB01609 | Deferasirox | An iron chelator used to treat chronic iron overload caused by blood transfusions. Also used in patients with non-transfusion-dependent thalassemia syndromes, and in patients with elevated liver iron concentration and serum ferritin. |
| DB01045 | Rifampicin | An antibiotic used to treat several types of mycobacterial infections including Mycobacterium avium complex, leprosy, and in combination with other antibacterials to treat latent or active tuberculosis. |
| DB00661 | Verapamil | A calcium channel blocker used for the short-term treatment of angina, arrhythmia, and hypertension. |
| DB00641 | Simvastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular events including myocardial infarction and stroke. |
| DB01138 | Sulfinpyrazone | A platelet inhibitory and uricosuric agent used to inhibit thrombotic and embolic processes and to manage the chronic phases of gout . |
| DB00471 | Montelukast | A leukotriene receptor antagonist used as part of an asthma therapy regimen, to prevent exercise induced bronchoconstriction, and to treat seasonal allergic rhinitis. |
| DB06712 | Nilvadipine | For the management of vasospastic angina, chronic stable angina and hypertension. |
| DB01583 | Liotrix | May be used to treat primary, secondary or tertiary hypothyroidism. May also be used to suppress thyroid stimulating hormone (TSH) secretion in patients with simple (nontoxic) goiter, subacute or chronic... |
| DB00764 | Mometasone | A corticosteroid used to treat asthma and allergic rhinitis. |
| DB00834 | Mifepristone | A cortisol receptor blocker used to treat Cushing's syndrome, and to terminate pregnancies up to 70 days gestation. |
| DB08881 | Vemurafenib | A kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation. |
| DB00398 | Sorafenib | A kinase inhibitor used in the treatment of unresectable liver carcinoma and advanced renal carcinoma. |
| DB06210 | Eltrombopag | A thrombopoietin receptor agonist used to treat thrombocytopenia or aplastic anemia associated with various etiologies. |
| DB04725 | Licofelone | For the management of osteoarthritis. |
| DB01393 | Bezafibrate | A lipid-lowering fibrate used in the management of primary and secondary hyperlipidaemia, when there is a lack of clinical improvement following lifestyle modifications or correction of the underlying disorder. |
| DB01698 | Rutin | A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc. It has been used therapeutically to decrease capillary fragility. |
| DB08901 | Ponatinib | A kinase inhibitor used to treat patients with various types of chronic myeloid leukemia (CML). |
| DB09054 | Idelalisib | An antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL). |
| DB13919 | Candesartan | Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is available as a prodrug in the form of Candesartan cilexetil. |
| DB11633 | Isavuconazole | Indicated for patients 18 years of age and older for the treatment of invasive aspergillosis [FDA Label].
Indicated for patients 18 years of age and older for the treatment of... |
| DB11632 | Opicapone | A catechol-O-methyltransferase inhibitor used to treat Parkinson's disease in patients currently receiving levodopa and a dopa decarboxylase inhibitor. |
| DB11753 | Rifamycin | An antibacterial used to treat traveler's diarrhea. |
| DB12245 | Triclabendazole | An anthelmintic drug used to treat fascioliasis. |
| DB12015 | Alpelisib | Alpelisib is indicated in combination with fulvestrant to treat postmenopausal women, and men, with advanced or metastatic breast cancer.[Label] This cancer must be hormone receptor (HR)-positive, human epidermal growth factor... |
| DB12781 | Balaglitazone | Balaglitazone has been used in trials studying the treatment of Diabetes Mellitus, Type 2. |
| DB09201 | Ciglitazone | Developed by Takeda Pharmaceuticals in the early 1980s, it is considered the prototypical compound for the thiazolidinedione class.
Ciglitazone was never used as a medication, but it sparked interest in... |
| DB09198 | Lobeglitazone | Lobeglitazone was approved by the Ministry of Food and Drug Safety (South Korea) in 2013, and is being monitored by postmarketing surveillance until 2019. Lobeglitazone is not approved for use... |
| DB09199 | Netoglitazone | Netoglitazone (MCC-555) is a hypoglycemic agent. |
| DB09200 | Rivoglitazone | Rivoglitazone (INN) is a thiazolidinedione undergoing research for use in the treatment of type 2 diabetes. It is being developed by Daiichi Sankyo Co. |
| DB14512 | Mometasone furoate | A corticosteroid used to treat asthma, allergic rhinitis, nasal congestion, nasal polyps, dermatitis, and pruritus. |
| DB01124 | Tolbutamide | A sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus. |
| DB01115 | Nifedipine | A dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension. |
| DB00169 | Cholecalciferol | A form of Vitamin D used in the treatment of specific medical conditions such as refractory rickets, hypoparathyroidism, and familial hypophosphatemia, as well as osteoporosis and chronic kidney disease. |
| DB01076 | Atorvastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. |
| DB00678 | Losartan | An angiotensin receptor blocker used to treat hypertension and diabetic nephropathy, and is used to reduce the risk of stroke. |
| DB00784 | Mefenamic acid | An NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea. |
| DB13179 | Troleandomycin | For the treatment of bacterial infection. |
| DB00973 | Ezetimibe | A cholesterol absorption inhibitor used to lower total cholesterol, LDL-C, Apo B, and non-HDL-C in primary hyperlipidemia and familial cholesterolemia. |
| DB01217 | Anastrozole | A competitive, selective, non-steroidal aromatase inhibitor used as adjuvant therapy for the treatment of hormone receptor-positive breast cancer in postmenopausal women. |
| DB12001 | Abemaciclib | A medication used to treat HR+ HER2- advanced or metastatic breast cancer. |
| DB00381 | Amlodipine | A calcium channel blocker used to treat hypertension and angina. |
| DB15444 | Elexacaftor | Elexacaftor, in combination with ivacaftor and tezacaftor as the combination product TrikaftaTM, is indicated for the treatment of cystic fibrosis (CF) in patients 12 years of age and older who... |