Showing BioInteractions for Zinc (DB01593)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.

Target Mediated Interactions 10
Enzyme Mediated Interactions 1

	Interacting Group	Interacting Drugs
	Zinc is a Estrogen receptor alpha cofactor
1	Estrogen receptor alpha agonists	Allylestrenol, Bazedoxifene, Chlorotrianisene, Clomifene, Conjugated estrogens, Danazol, Desogestrel, Dienestrol, Diethylstilbestrol, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estramustine, Estriol, Estrone, Estrone sulfate, Ethinylestradiol, Ethynodiol diacetate, Gestrinone, Lasofoxifene, Medroxyprogesterone acetate, Mestranol, Norgestimate, Ospemifene, Phenolphthalein, Polyestradiol phosphate, Progesterone, Quinestrol, Raloxifene, Tamoxifen, Tibolone
2	Estrogen receptor alpha modulators	Quinestrol, Toremifene
3	Estrogen receptor alpha antagonists	Bazedoxifene, Clomifene, Fluoxymesterone, Fulvestrant, Gestrinone, Lasofoxifene, Melatonin, Naloxone, Ospemifene, Tamoxifen, Tibolone
4	Estrogen receptor alpha inhibitors	Progesterone, Testosterone
5	Estrogen receptor alpha negative modulators	Lasofoxifene
6	Estrogen receptor alpha binders	Fluoroestradiol F-18, Prasterone, Zinc chloride, Zinc sulfate, unspecified form
7	Estrogen receptor alpha ligands	Synthetic Conjugated Estrogens, A, Synthetic Conjugated Estrogens, B

	Interacting Group	Interacting Drugs
	Zinc is a Histone deacetylase 1 cofactor
1	Histone deacetylase 1 inhibitors	Fingolimod, Romidepsin, Vorinostat
2	Histone deacetylase 1 antagonists	Romidepsin
3	Histone deacetylase 1 cofactors	Zinc chloride, Zinc sulfate, unspecified form

	Interacting Group	Interacting Drugs
	Zinc is a Histone deacetylase 4 cofactor
1	Histone deacetylase 4 inhibitors	Romidepsin
2	Histone deacetylase 4 cofactors	Zinc chloride, Zinc sulfate, unspecified form

	Interacting Group	Interacting Drugs
	Zinc is a Histone deacetylase 8 cofactor
1	Histone deacetylase 8 cofactors	Iron, Zinc chloride, Zinc sulfate, unspecified form

	Interacting Group	Interacting Drugs
	Zinc is a Aspartoacylase cofactor
1	Aspartoacylase cofactors	Zinc chloride, Zinc sulfate, unspecified form

	Interacting Group	Interacting Drugs
	Zinc is a Tumor protein p73 cofactor

	Interacting Group	Interacting Drugs
	Zinc is a DAN domain family member 5 cofactor

	Interacting Group	Interacting Drugs
	Zinc is a Amyloid-like protein 1 cofactor
1	Amyloid-like protein 1 cofactors	Copper
2	Amyloid-like protein 1 ligands	Zinc chloride, Zinc sulfate, unspecified form

	Interacting Group	Interacting Drugs
	Zinc is a Amyloid-like protein 2 cofactor
1	Amyloid-like protein 2 ligands	Zinc chloride, Zinc sulfate, unspecified form

	Interacting Group	Interacting Drugs
	Zinc is a Amyloid beta A4 protein cofactor
1	Amyloid beta A4 protein binders	Florbetaben F-18, Florbetapir (18F), Flutemetamol (18F)
2	Amyloid beta A4 protein ligands	Zinc chloride, Zinc sulfate, unspecified form
3	Amyloid beta A4 protein inhibitors	Tromethamine

	Interacting Group	Interacting Drugs
	Zinc is a Carbonic anhydrase 1 substrate
1	Carbonic anhydrase 1 inhibitors	Acetazolamide, Amlodipine, Bendroflumethiazide, Benzthiazide, Brinzolamide, Chlorothiazide, Chlorthalidone, Cyclothiazide, Diazoxide, Diclofenamide, Dorzolamide, Ellagic acid, Ethinamate, Ethoxzolamide, Hydroflumethiazide, Methazolamide, Methocarbamol, Methyclothiazide, Quinethazone, Sodium carbonate, Sodium sulfate, Topiramate, Trichlormethiazide, Zonisamide
2	Carbonic anhydrase 1 ligands	Zinc acetate