Bone Metastases

Also known as: Bone metastases / Bony secondaries / Bone cancer metastatic / Bony metastases / Osteolytic bone metastases / Metastases to bone / Metastasis to bone / Secondary malignant neoplasm of bone / Secondary malignant neoplasm of bone and bone marrow

DrugDrug NameDrug Description
DB06643DenosumabA RANK ligand (RANKL) inhibitor used for the management of osteoporosis in patients at high risk for bone fractures.
DB00710IbandronateA bisphosphonate used to treat osteoporosis in postmenopausal women.
DB13944Testosterone enanthateAn androgen used to treat low or absent testosterone.
DB00399Zoledronic acidA bisphosphonate used to treat malignancy associated hypercalcemia, multiple myeloma, and bone metastasis from solid tumors.
DrugDrug NameTargetType
DB06643DenosumabTumor necrosis factor ligand superfamily member 11target
DB00710IbandronateFarnesyl pyrophosphate synthasetarget
DB00710IbandronateHydroxylapatitetarget
DB13944Testosterone enanthateAndrogen receptortarget
DB13944Testosterone enanthateCytochrome P450 3A4enzyme
DB13944Testosterone enanthateAmine oxidase [flavin-containing] Aenzyme
DB13944Testosterone enanthateCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB13944Testosterone enanthateSerum albumincarrier
DB13944Testosterone enanthateSex hormone-binding globulincarrier
DB13944Testosterone enanthateCytochrome P450 3A5enzyme
DB13944Testosterone enanthateCytochrome P450 3A7enzyme
DB13944Testosterone enanthateSolute carrier organic anion transporter family member 1A2transporter
DB13944Testosterone enanthateSolute carrier family 22 member 8transporter
DB13944Testosterone enanthateSolute carrier family 22 member 7transporter
DB13944Testosterone enanthateP-glycoprotein 1transporter
DB13944Testosterone enanthateSodium/bile acid cotransportertransporter
DB13944Testosterone enanthateSolute carrier family 22 member 3transporter
DB13944Testosterone enanthateSolute carrier family 22 member 4transporter
DB13944Testosterone enanthateATP-binding cassette sub-family G member 2transporter
DB13944Testosterone enanthateCytochrome P450 1A1enzyme
DB13944Testosterone enanthateCytochrome P450 2A13enzyme
DB13944Testosterone enanthateCytochrome P450 2B6enzyme
DB13944Testosterone enanthateCytochrome P450 2C19enzyme
DB13944Testosterone enanthateCytochrome P450 2C8enzyme
DB13944Testosterone enanthateCytochrome P450 2C9enzyme
DB13944Testosterone enanthateCytochrome P450 3A43enzyme
DB13944Testosterone enanthateEstrogen receptor alphatarget
DB13944Testosterone enanthateMineralocorticoid receptortarget
DB13944Testosterone enanthate3-oxo-5-alpha-steroid 4-dehydrogenaseenzyme
DB13944Testosterone enanthateCytochrome P450 19A1enzyme
DB00399Zoledronic acidFarnesyl pyrophosphate synthasetarget
DB00399Zoledronic acidGeranylgeranyl pyrophosphate synthasetarget
DB00399Zoledronic acidHydroxylapatitetarget
DB00399Zoledronic acidMultidrug resistance-associated protein 1transporter
DrugDrug NamePhaseStatusCount
DB00470Dronabinol0Recruiting1
DB12775Abituzumab1Completed1
DB06724Calcium carbonate1Not Yet Recruiting1
DB00958Carboplatin1Completed1
DB00099Filgrastim1Not Yet Recruiting1
DB01611Hydroxychloroquine1Terminated1
DB12381Merestinib1Recruiting1
DB01229Paclitaxel1Completed1
DB06809Plerixafor1Not Yet Recruiting1
DB12905Samarium Sm-1531Not Yet Recruiting1
DB00072Trastuzumab1Completed1
DB00399Zoledronic acid1Completed1
DB00958Carboplatin1 / 2Recruiting1
DB01254Dasatinib1 / 2Active Not Recruiting1
DB01248Docetaxel1 / 2Completed1
DB00997Doxorubicin1 / 2Recruiting1
DB00441Gemcitabine1 / 2Recruiting1
DB00762Irinotecan1 / 2Recruiting1
DB14928Lacnotuzumab1 / 2Terminated1
DB01206Lomustine1 / 2Recruiting1
DB01229Paclitaxel1 / 2Recruiting1
DB08913Radium Ra 223 Dichloride1 / 2Active Not Recruiting1
DB09566Radium Ra 223 Dichloride1 / 2Active Not Recruiting1
DB08913Radium Ra 223 Dichloride1 / 2Completed1
DB09566Radium Ra 223 Dichloride1 / 2Completed1
DB12813Radium Ra-2231 / 2Active Not Recruiting1
DB00399Zoledronic acid1 / 2Active Not Recruiting1
DB00630Alendronic acid2Terminated1
DB01128Bicalutamide2Terminated1
DB05153Cabozantinib2Completed1
DB08875Cabozantinib2Completed1
DB01101Capecitabine2Unknown Status1
DB00515Cisplatin2Completed1
DB06643Denosumab2Recruiting2
DB11714Durvalumab2Recruiting1
DB08899Enzalutamide2Recruiting3
DB00813Fentanyl2Terminated1
DB01026Ketoconazole2Terminated1
DB09035Nivolumab2Recruiting1
DB08913Radium Ra 223 Dichloride2Completed2
DB06573Rebimastat2Completed1
DB12403Samarium2Completed1
DB06688Sipuleucel-T2Active Not Recruiting1
DB12546Strontium chloride Sr-892Completed1
DB00399Zoledronic acid2Recruiting1
DB00399Zoledronic acid2 / 3Completed1
DB00316Acetaminophen3Recruiting1
DB06643Denosumab3Completed4
DB06643Denosumab3Recruiting1
DB01234Dexamethasone3Completed1
DB14649Dexamethasone acetate3Completed1
DB00441Gemcitabine3Terminated1
DB00956Hydrocodone3Recruiting1
DB00465Ketorolac3Recruiting1
DB00295Morphine3Recruiting1
DB00497Oxycodone3Recruiting1
DB08913Radium Ra 223 Dichloride3Completed1
DB09566Radium Ra 223 Dichloride3Completed1
DB00399Zoledronic acid3Completed4
DB00399Zoledronic acid4Completed1
DB00945Acetylsalicylic acidNot AvailableCompleted1
DB01225EnoxaparinNot AvailableCompleted1
DB08913Radium Ra 223 DichlorideNot AvailableRecruiting1
DB00243RanolazineNot AvailableCompleted1
DB00072TrastuzumabNot AvailableActive Not Recruiting1
DB05773Trastuzumab emtansineNot AvailableActive Not Recruiting1