Community Acquired Pneumonia (CAP)

Also known as: Community-Acquired Pneumonia (CAP) / Pneumonia, Community-Acquired / Community Aquired Pneumonia / Community Acquired Pneumonia / Community-Acquired Pneumonia / Pneumonia / Pneumonia NOS / Pulmonitis

DrugDrug NameDrug Description
DB01060AmoxicillinA penicillin derivative used for the treatment of infections caused by gram-positive bacteria, in particular streptococcal bacteria causing upper respiratory tract infections.
DB00207AzithromycinA macrolide antibiotic used to treat a variety of bacterial infections.
DB01327CefazolinA broad-spectrum cephalosporin antibiotic mainly used for the treatment of skin bacterial infections and other moderate to severe bacterial infections in the lung, bone, joint, stomach, blood, heart valve, and urinary tract.
DB01066CefditorenA broad-spectrum third-generation cephalosporin antibiotic typically used to treat bacterial infections of the skin and respiratory tract.
DB00671CefiximeA third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections.
DB00493CefotaximeA third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections.
DB01416CefpodoximeA third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including gonorrhea, community acquired pneumonia, and sinusitis.
DB01150CefprozilA cephalosporin antibiotic used in the treatment of various bacterial infections, such as pharyngitis, tonsillitis, otitis media, and uncomplicated skin infections.
DB06590Ceftaroline fosamilAn antibacterial agent used to treat various bacterial infections, such as acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia.
DB04918CeftobiproleA cephalosporin antibiotic used to treat both community and hospital-acquired pneumonia caused by susceptible bacteria.
DB01212CeftriaxoneA broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections at various locations, such as in the respiratory tract, skin, soft tissue, and urinary tract.
DB01211ClarithromycinA macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection.
DB01190ClindamycinAn antibiotic used to treat serious infections caused by susceptible anaerobic bacteria, such as intra-abdominal or pelvic infections, osteomyelitis, diabetic foot ulcers, and dental infections.
DB00303ErtapenemA carbapenem antibiotic used for the treatment of moderate to severe bacterial infections caused by specific sensitive organisms.
DB00199ErythromycinA macrolide antibiotic used to treat and prevent a variety of bacterial infections.
DB01155GemifloxacinA quinolone antibacterial agent used for the treatment of acute bacterial exacerbation of chronic bronchitis and mild to moderate community-acquired pneumonia caused by susceptible bacteria.
DB01137LevofloxacinA fluoroquinolone used to treat infections including the upper respiratory tract, skin and skin structure, urinary tract, as well as pneumonia, chronic bacterial prostatitis, post exposure treatment of inhaled anthrax, and the plague.
DB00601LinezolidAn oxazolidinone antibiotic used to treat susceptible strains of multidrug resistant bacterial infections.
DB00218MoxifloxacinA fluoroquinolone antibiotic used to treat various bacterial infections.
DB01165OfloxacinAn antibacterial agent used for the treatment of bacterial infections in many parts of the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract.
DB00713OxacillinA penicillin antibiotic used to treat a number of susceptible bacterial infections.
DB00417PhenoxymethylpenicillinA penicillin antibiotic used to prevent and treat mild to moderately severe infections in the respiratory tract, skin, and soft tissues.
DB09324SulbactamAn beta-lactamase inhibitor antibiotic combined with other antibiotics to treat a variety of susceptible bacterial infections.
DB00560TigecyclineA glycylcycline antibiotic used to treat a number of susceptible bacterial infections.
DrugDrug NameTargetType
DB01060AmoxicillinPenicillin-binding protein 1Atarget
DB01060AmoxicillinSolute carrier family 15 member 1transporter
DB01060AmoxicillinSolute carrier family 15 member 2transporter
DB01060AmoxicillinSolute carrier family 22 member 6transporter
DB00207Azithromycin23S ribosomal RNAtarget
DB00207AzithromycinP-glycoprotein 1transporter
DB00207AzithromycinCytochrome P450 3A4enzyme
DB00207AzithromycinProtein-arginine deiminase type-4target
DB00207AzithromycinCanalicular multispecific organic anion transporter 1transporter
DB01327CefazolinSerum paraoxonase/arylesterase 1target
DB01327CefazolinSerum albumincarrier
DB01327CefazolinSolute carrier family 22 member 6transporter
DB01327CefazolinSolute carrier family 22 member 8transporter
DB01327CefazolinSolute carrier family 22 member 11transporter
DB01327CefazolinPenicillin-binding protein 1Atarget
DB01327CefazolinPenicillin-binding protein 1Btarget
DB01327CefazolinPenicillin-binding protein 2target
DB01327CefazolinPenicillin-binding protein 1Ctarget
DB01327CefazolinPeptidoglycan synthase FtsItarget
DB01327CefazolinMultidrug resistance-associated protein 4transporter
DB01327CefazolinThiopurine S-methyltransferaseenzyme
DB01327CefazolinInterleukin-15target
DB01327CefazolinInterleukin-2target
DB01066CefditorenPenicillin-binding protein 1Atarget
DB01066CefditorenPenicillin-binding protein 2Btarget
DB00671CefiximePenicillin-binding protein 2target
DB00671CefiximeSolute carrier family 22 member 5transporter
DB00671CefiximeSolute carrier family 15 member 1transporter
DB00671CefiximeSolute carrier family 15 member 2transporter
DB00493CefotaximePenicillin-binding protein 3target
DB00493CefotaximeSolute carrier family 15 member 1transporter
DB00493CefotaximeSolute carrier family 15 member 2transporter
DB00493CefotaximeSolute carrier family 22 member 6transporter
DB00493CefotaximeSolute carrier family 22 member 8transporter
DB00493CefotaximeSolute carrier family 22 member 11transporter
DB00493CefotaximeSolute carrier family 22 member 7transporter
DB00493CefotaximePenicillin-binding protein 1btarget
DB00493CefotaximePenicillin-binding protein 2atarget
DB00493CefotaximePenicillin-binding protein 1Atarget
DB00493CefotaximePenicillin-binding protein 2Btarget
DB00493CefotaximeSolute carrier family 22 member 6target
DB00493CefotaximeSolute carrier family 22 member 8target
DB00493CefotaximeSolute carrier family 22 member 11target
DB00493CefotaximeSolute carrier family 22 member 7target
DB00493CefotaximeSolute carrier family 15 member 1target
DB00493CefotaximeSerum albumintarget
DB00493CefotaximeBeta-lactamasetarget
DB00493CefotaximeSolute carrier family 15 member 2target
DB01416CefpodoximePeptidoglycan synthase FtsItarget
DB01150CefprozilPenicillin-binding protein 1Atarget
DB01150CefprozilPenicillin-binding protein 2xtarget
DB01150CefprozilPenicillin-binding protein 2Btarget
DB04918CeftobiproleMecAtarget
DB04918CeftobiprolePenicillin-binding protein 2xtarget
DB04918CeftobiprolePeptidoglycan synthase FtsItarget
DB01212CeftriaxoneSerum albumincarrier
DB01212CeftriaxoneSolute carrier family 15 member 1transporter
DB01212CeftriaxoneSolute carrier family 15 member 2transporter
DB01212CeftriaxoneSolute carrier family 22 member 6transporter
DB01212CeftriaxoneSolute carrier family 22 member 8transporter
DB01212CeftriaxoneSolute carrier family 22 member 11transporter
DB01212CeftriaxonePenicillin-binding protein 2Btarget
DB01212CeftriaxoneGlutamine synthetaseenzyme
DB01212CeftriaxoneSolute carrier family 22 member 11target
DB01212CeftriaxoneSolute carrier family 22 member 6target
DB01212CeftriaxoneSolute carrier family 22 member 8target
DB01212CeftriaxoneSolute carrier family 15 member 1target
DB01211Clarithromycin50S ribosomal protein L10target
DB01211ClarithromycinCytochrome P450 3A4enzyme
DB01211ClarithromycinCytochrome P450 3A5enzyme
DB01211ClarithromycinP-glycoprotein 1transporter
DB01211ClarithromycinSolute carrier family 22 member 7transporter
DB01211ClarithromycinPotassium voltage-gated channel subfamily H member 2target
DB01211ClarithromycinSolute carrier organic anion transporter family member 1B1target
DB01211ClarithromycinSolute carrier organic anion transporter family member 1B3target
DB01211ClarithromycinBile salt export pumptransporter
DB01190Clindamycin50S ribosomal protein L10target
DB01190ClindamycinCytochrome P450 3A4enzyme
DB01190Clindamycin23S ribosomal RNAtarget
DB00303ErtapenemPenicillin-binding protein 2target
DB00303ErtapenemPeptidoglycan synthase FtsItarget
DB00303ErtapenemPenicillin-binding protein 1Atarget
DB00303ErtapenemD-alanyl-D-alanine carboxypeptidase DacCtarget
DB00303ErtapenemD-alanyl-D-alanine carboxypeptidase DacBtarget
DB00303ErtapenemPenicillin-binding protein 1Btarget
DB00303ErtapenemPeptidoglycan synthase FtsItarget
DB00303ErtapenemPenicillin-binding protein 2target
DB00199Erythromycin23S ribosomal RNAtarget
DB00199ErythromycinCytochrome P450 3A4enzyme
DB00199ErythromycinCytochrome P450 3A7enzyme
DB00199ErythromycinP-glycoprotein 1transporter
DB00199ErythromycinSolute carrier organic anion transporter family member 1B1transporter
DB00199ErythromycinMotilin receptortarget
DB00199ErythromycinPotassium voltage-gated channel subfamily H member 2target
DB00199ErythromycinCytochrome P450 3A5enzyme
DB00199ErythromycinSolute carrier organic anion transporter family member 1B3transporter
DB00199ErythromycinBile salt export pumptransporter
DB00199ErythromycinCanalicular multispecific organic anion transporter 1transporter
DB00199ErythromycinSolute carrier organic anion transporter family member 1A2transporter
DB01155GemifloxacinDNA gyrase subunit Atarget
DB01155GemifloxacinDNA topoisomerase 4 subunit Atarget
DB01155GemifloxacinCytochrome P450 1A2enzyme
DB01137LevofloxacinDNA gyrase subunit Atarget
DB01137LevofloxacinDNA topoisomerase 4 subunit Atarget
DB01137LevofloxacinDNA topoisomerase 2-alphatarget
DB01137LevofloxacinCytochrome P450 1A2enzyme
DB01137LevofloxacinSolute carrier family 22 member 2transporter
DB01137LevofloxacinP-glycoprotein 1transporter
DB01137LevofloxacinSolute carrier family 22 member 4transporter
DB01137LevofloxacinSolute carrier family 22 member 6transporter
DB01137LevofloxacinCytochrome P450 3A4enzyme
DB01137LevofloxacinMultidrug and toxin extrusion protein 1transporter
DB01137LevofloxacinMultidrug and toxin extrusion protein 2transporter
DB01137LevofloxacinCytochrome P450 2C9enzyme
DB00601Linezolid23S ribosomal RNAtarget
DB00601LinezolidAmine oxidase [flavin-containing] Aenzyme
DB00601LinezolidAmine oxidase [flavin-containing] Benzyme
DB00218MoxifloxacinDNA gyrase subunit Atarget
DB00218MoxifloxacinDNA topoisomerase 4 subunit Atarget
DB00218MoxifloxacinDNA topoisomerase 2-alphatarget
DB00218MoxifloxacinCytochrome P450 1A2enzyme
DB01165OfloxacinDNA gyrase subunit Atarget
DB01165OfloxacinDNA topoisomerase 4 subunit Atarget
DB01165OfloxacinDNA topoisomerase 2-alphatarget
DB01165OfloxacinCytochrome P450 1A2enzyme
DB01165OfloxacinSolute carrier family 22 member 5transporter
DB01165OfloxacinMultidrug resistance-associated protein 1transporter
DB01165OfloxacinSolute carrier family 22 member 6transporter
DB01165OfloxacinCanalicular multispecific organic anion transporter 1transporter
DB01165OfloxacinSolute carrier family 22 member 4transporter
DB01165OfloxacinBile salt export pumptransporter
DB00713OxacillinPenicillin-binding protein 1Atarget
DB00713OxacillinSolute carrier family 15 member 1transporter
DB00713OxacillinSolute carrier family 15 member 2transporter
DB00713OxacillinPenicillin-binding protein 3target
DB00713OxacillinPenicillin-binding protein 2atarget
DB00713OxacillinPenicillin-binding protein 1Atarget
DB00713OxacillinPenicillin-binding protein 2Btarget
DB00713OxacillinPenicillin-binding protein 1btarget
DB00713OxacillinSolute carrier family 15 member 1target
DB00713OxacillinPenicillin-binding protein 2target
DB00713OxacillinSolute carrier family 15 member 2target
DB00417PhenoxymethylpenicillinPenicillin-binding protein 1Atarget
DB00417PhenoxymethylpenicillinMecA PBP2' (penicillin binding protein 2')target
DB00417PhenoxymethylpenicillinD-alanyl-D-alanine carboxypeptidase DacBtarget
DB00417PhenoxymethylpenicillinPenicillin acylasetarget
DB00417PhenoxymethylpenicillinSolute carrier family 15 member 1target
DB09324SulbactamBeta-lactamasetarget
DB00560Tigecycline30S ribosomal protein S9target
DB00560Tigecycline16S ribosomal RNAtarget
DB00560Tigecycline30S ribosomal protein S14target
DB00560Tigecycline30S ribosomal protein S13target
DB00560Tigecycline30S ribosomal protein S19target
DB00560Tigecycline30S ribosomal protein S12target
DrugDrug NamePhaseStatusCount
DB06087Friulimicin B1Terminated1
DB08816Ticagrelor1Completed1
DB01060Amoxicillin2Recruiting1
DB00766Clavulanic acid2Recruiting1
DB00303Ertapenem2Completed1
DB12190Faropenem2Completed1
DB00062Human Serum Albumin2Completed1
DB01137Levofloxacin2Completed1
DB01137Levofloxacin2Terminated1
DB06600Nemonoxacin2Completed2
DB12339Radezolid2Completed1
DB00976Telithromycin2Unknown Status1
DB12479Zabofloxacin2Terminated1
DB01060Amoxicillin2 / 3Completed1
DB01060Amoxicillin2 / 3Recruiting1
DB06590Ceftaroline fosamil2 / 3Completed1
DB01212Ceftriaxone2 / 3Completed1
DB00766Clavulanic acid2 / 3Completed1
DB00207Azithromycin3Completed3
DB00207Azithromycin3Withdrawn1
DB12430BC-37813Completed2
DB00443Betamethasone3Recruiting1
DB00438Ceftazidime3Recruiting1
DB14733Ceftobiprole medocaril3Recruiting1
DB01212Ceftriaxone3Recruiting1
DB06219Dalbavancin3Withdrawn1
DB11943Delafloxacin3Completed1
DB00303Ertapenem3Unknown Status1
DB12190Faropenem3Unknown Status1
DB00062Human Serum Albumin3Not Yet Recruiting1
DB00741Hydrocortisone3Recruiting1
DB12825Lefamulin3Completed2
DB01137Levofloxacin3Completed1
DB00601Linezolid3Completed2
DB00601Linezolid3Withdrawn1
DB14644Methylprednisolone hemisuccinate3Not Yet Recruiting1
DB00218Moxifloxacin3Completed3
DB06600Nemonoxacin3Completed1
DB00635Prednisone3Completed1
DB00641Simvastatin3Unknown Status1
DB00560Tigecycline3Completed1
DB01060Amoxicillin4Completed3
DB01060Amoxicillin4Recruiting3
DB01060Amoxicillin4Terminated1
DB00415Ampicillin4Terminated1
DB00207Azithromycin4Completed1
DB00207Azithromycin4Recruiting2
DB06590Ceftaroline fosamil4Recruiting1
DB01212Ceftriaxone4Completed2
DB01212Ceftriaxone4Not Yet Recruiting1
DB01212Ceftriaxone4Recruiting1
DB01112Cefuroxime4Completed1
DB01211Clarithromycin4Completed1
DB00766Clavulanic acid4Completed2
DB00766Clavulanic acid4Recruiting1
DB01234Dexamethasone4Terminated1
DB00254Doxycycline4Recruiting1
DB00741Hydrocortisone4Recruiting1
DB01137Levofloxacin4Completed2
DB01137Levofloxacin4Recruiting2
DB01137Levofloxacin4Unknown Status1
DB00959Methylprednisolone4Completed1
DB00959Methylprednisolone4Recruiting1
DB00916Metronidazole4Unknown Status1
DB01017Minocycline4Recruiting1
DB00218Moxifloxacin4Recruiting2
DB00218Moxifloxacin4Terminated1
DB00218Moxifloxacin4Unknown Status1
DB00713Oxacillin4Completed1
DB00319Piperacillin4Recruiting1
DB00641Simvastatin4Withdrawn1
DB09153Sodium chloride4Completed1
DB09153Sodium chloride4Recruiting1
DB01606Tazobactam4Recruiting1
DB00976Telithromycin4Completed1
DB01273Varenicline4Completed1
DB00802AlfentanilNot AvailableRecruiting1
DB00479AmikacinNot AvailableRecruiting1
DB00513Aminocaproic acidNot AvailableRecruiting1
DB00207AzithromycinNot AvailableCompleted1
DB00207AzithromycinNot AvailableNot Yet Recruiting1
DB00207AzithromycinNot AvailableTerminated1
DB00559BosentanNot AvailableRecruiting1
DB01326CefamandoleNot AvailableNot Yet Recruiting1
DB01413CefepimeNot AvailableRecruiting1
DB01212CeftriaxoneNot AvailableNot Yet Recruiting1
DB00369CidofovirNot AvailableRecruiting1
DB00501CimetidineNot AvailableCompleted1
DB00537CiprofloxacinNot AvailableRecruiting1
DB00363ClozapineNot AvailableRecruiting1
DB00199ErythromycinNot AvailableNot Yet Recruiting1
DB00736EsomeprazoleNot AvailableCompleted1
DB00927FamotidineNot AvailableCompleted1
DB00828FosfomycinNot AvailableRecruiting1
DB00502HaloperidolNot AvailableRecruiting1
DB05381HistamineNot AvailableCompleted1
DB00598LabetalolNot AvailableRecruiting1
DB12770LafutidineNot AvailableCompleted1
DB00448LansoprazoleNot AvailableCompleted1
DB04570LatamoxefNot AvailableNot Yet Recruiting1
DB08815LurasidoneNot AvailableRecruiting1
DB00959MethylprednisoloneNot AvailableRecruiting1
DB01618MolindoneNot AvailableRecruiting1
DB00218MoxifloxacinNot AvailableRecruiting1
DB00607NafcillinNot AvailableRecruiting1
DB01115NifedipineNot AvailableRecruiting1
DB13760NiperotidineNot AvailableCompleted1
DB00585NizatidineNot AvailableCompleted1
DB00338OmeprazoleNot AvailableCompleted1
DB00497OxycodoneNot AvailableRecruiting1
DB00213PantoprazoleNot AvailableCompleted1
DB00312PentobarbitalNot AvailableRecruiting1
DB00319PiperacillinNot AvailableRecruiting1
DB01129RabeprazoleNot AvailableCompleted1
DB00863RanitidineNot AvailableCompleted1
DB00728RocuroniumNot AvailableRecruiting1
DB08806Roxatidine acetateNot AvailableCompleted1
DB00658SevelamerNot AvailableRecruiting1
DB09153Sodium chlorideNot AvailableRecruiting1
DB00421SpironolactoneNot AvailableRecruiting1
DB01606TazobactamNot AvailableRecruiting1
DB00684TobramycinNot AvailableRecruiting1
DB00302Tranexamic acidNot AvailableRecruiting1
DB00512VancomycinNot AvailableRecruiting1
DB01339VecuroniumNot AvailableRecruiting1
DB00682WarfarinNot AvailableRecruiting1
DB00246ZiprasidoneNot AvailableRecruiting1
DB00425ZolpidemNot AvailableRecruiting1