OAT3/SLC22A8 Substrates

Name
OAT3/SLC22A8 Substrates
Accession Number
DBCAT002661
Description
Not Available
Drugs
DrugDrug Description
Aminohippuric acidA hippuric acid derivative injection utilized in the measurement of effective renal plasma flow (ERPF) and functional capacity of the renal excretory system.
Glutaric AcidNot Available
AcyclovirA guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster.
DinoprostoneA prostaglandin used to induce labor or abortion as well as to treat nonmetastatic gestational trophoblastic disease.
CefazolinA broad-spectrum cephalosporin antibiotic mainly used for the treatment of skin bacterial infections and other moderate to severe bacterial infections in the lung, bone, joint, stomach, blood, heart valve, and urinary tract.
MethotrexateAn antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis.
CephalexinA first generation cephalosporin used to treat certain susceptible bacterial infections.
Taurocholic acidThe product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats...
Conjugated estrogensA mixture of estrogens used in estrogen replacement therapy for menopause and hypoestrogenism, used in the treatment of various malignancies, and used in the treatment of postmenopausal osteoporosis.
Cyclic adenosine monophosphateCyclic adenosine monophosphate (cAMP, cyclic AMP or 3'-5'-cyclic adenosine monophosphate) is a molecule that is important in many biological processes; it is derived from adenosine triphosphate (ATP).
CefacetrileCefacetrile is a broad-spectrum first generation cephalosporin antibiotic effective in Gram-positive and Gram-negative bacterial infections.
Tenofovir disoproxilA nucleotide analog reverse transcriptase inhibitor used in the treatment of Hepatitis B infection and used in the management of HIV-1 infection.
CimetidineA histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion.
BenzylpenicillinA penicillin used for the treatment of infections caused by gram-positive cocci, in particular streptococcal infections. This form of penicillin is typically used in intravenous or long-acting injectable formulations due to poor oral absorption.
EstroneAn estrogen used to treat perimenopausal and postmenopausal symptoms.
PravastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and to reduce the risk of cardiovascular events, including myocardial infarction and stroke.
BumetanideA sulfamyl diuretic used to treat edema in congestive heart failure, hepatic and renal disease, and nephrotic syndrome.
CaptoprilAn ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy.
CefaclorA second generation cephalosporin used to treat a wide variety of infections in the body.
CefdinirA third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections.
CefotiamFor treatment of severe infections caused by susceptible bacteria.
CeftibutenA third-generation cephalosporin antibiotic commonly used in the treatment of acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsillitis.
CeftizoximeA third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including lower respiratory tract infection, urinary tract infection, and gonorrhea.
CefaloridineCephaloridine or cefaloridine is a first generation semisynthetic cephalosporin. It is derived from cephalosporin C and is a zwitterion at physiological pH.
Cholic AcidA bile acid used for the treatment of bile acid synthesis disorders due to single enzyme defects and as an adjunctive treatment of peroxisomal disorders with disrupted liver function.
HydrocortisoneA glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
EdaravoneA free radical scavenger used to delay the progression of ALS.
EstradiolAn estrogenic steroid used to treat vasomotor symptoms of vulvar and vaginal atrophy in menopause, hypoestrogenism, prevention of postmenopausal osteoporosis, treatment of breast cancer, and advanced androgen-dependent carcinoma of the prostate.
FamotidineA histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome.
FexofenadineA selective H1-antagonist for the symptomatic treatment of seasonal allergic rhinitis and chronic idiopathic urticaria.
LeucovorinA folate analog used to treat the toxic effects of methotrexate and other folate antagonists, to treat megaloblastic anemia, and to provide palliative treatment of colorectal cancer.
QuinaprilAn ACE inhibitor prodrug used to treat hypertension, congestive heart failure, and slow rate of progression of renal disease.
RanitidineA histamine H2 antagonist used to treat duodenal ulcers, Zollinger-Ellison syndrome, gastric ulcers, GERD, and erosive esophagitis.
RosuvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
SitagliptinAn oral dipeptidyl peptidase-4 (DPP-4) inhibitor used for the management of type 2 diabetes mellitus.
TetracyclineAn antibiotic used to treat a wide variety of susceptible infections.
ValaciclovirAn guanine nucleoside antiviral used to treat herpes exacerbations.
ZidovudineA dideoxynucleoside used in the treatment of HIV infection.
IndomethacinA nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
FluoresceinA dye used in angiography or angioscopy of the iris and retina.
TrifluridineA nucleoside metabolic inhibitor used to treat keratoconjunctivitis and epithelial keratitis caused by simplex virus, and as a part of chemotherapy for certain types of metastatic gastrointestinal cancers.
Ellagic acidEllagic acid is being investigated for use in follicular lymphoma, brain injury in intrauterine growth restricted babies, obese adolescents, and solar lentigines.
CitrullineUsed for nutritional supplementation, also for treating dietary shortage or imbalance.
AlprostadilA medication used to treat erectile dysfunction.
SilibininCurrently being tested as a treatment of severe intoxications with hepatotoxic substances, such as death cap (Amanita phalloides) poisoning.
PiperacillinA penicillin antibiotic combined with tazobactam to treat piperacillin-resistant, piperacillin/tazobactam­ susceptible, β-lactamase generating strains of several bacteria.
TazobactamA beta lactamase inhibitor administered with antibiotics such as piperacillin and ceftolozane to prevent their degradation, resulting in increased efficacy.
Valproic acidAn anticonvulsant used to control complex partial seizures and both simple and complex absence seizures.
MercaptopurineAn antineoplastic agent used to treat acute lymphocytic leukemia.
Succinic acidFor nutritional supplementation, also for treating dietary shortage or imbalance
Oxalic AcidA strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted...
LevocarnitineA quaternary ammonium compound used to treat carnitine deficiency or to stimulate gastric and pancreatic secretions in hyperlipoproteinemia.
AllopurinolA xanthine oxidase inhibitor used to reduce urinary and serum uric acid concentrations in patients with gout, recurrent calcium oxalate calculi, and various malignancies.
OseltamivirA neuraminidase inhibitor used in the prophylaxis and treatment of influenza.
SaxagliptinAn DPP-4 inhibitor used for the management of type 2 diabetes mellitus.
EluxadolineA mixed mu-opioid receptor agonist used to treat irritable bowel syndrome with diarrhea.
AvibactamA non-β-lactam β-lactamase inhibitor used in combination with ceftazidime for the treatment of complicated intra-abdominal infections, complicated urinary tract infections, and hospital or ventilator-acquired pneumonia.
BaricitinibA Janus kinase inhibitor used to treat moderate to severe rheumatoid arthritis that has responded poorly to at least one TNF antagonist.
PemetrexedA folate analog used to treat mesothelioma and non-small cell lung cancer.
DoripenemAn antibiotic of the penem class used to treat complicated intra-abdominal and urinary tract infections.
Tenofovir alafenamideA nucleoside analog reverse transcriptase inhibitor used for the treatment of chronic hepatitis B virus infection in adults with compensated liver disease.
TenofovirTenofovir has been shown to be effective against HIV, herpes simplex virus-2, and hepatitis B virus. To know more about the specific product indications, please visit the information in the...
RelebactamA beta-lactamase inhibitor used to prevent hydrolysis of beta-lactam antibiotics, leading to increased effectiveness.
HydrochlorothiazideA thiazide diuretic used to treat edema associated with a number of conditions, and hypertension.
BudesonideA corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis.
DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
OxytetracyclineA tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections.
MedrysoneA topical glucocorticoid applied ophthalmically for the treatment of various ocular inflammatory or allergic conditions.
HydroflumethiazideA thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure and liver cirrhosis.
PolythiazideA thiazide diuretic used in the management of hypertension and treatment of edema.
Prednisolone phosphateA corticosteroid used to treat inflammation, immune reactions, as well as endocrine or neoplastic conditions.
ClofarabineA purine nucleoside used to treat relapsed or refractory acute lymphoblastic leukemia in patients 1 to 21 years old.
EmpagliflozinAn SGLT2 inhibitor used to manage type 2 diabetes mellitus.
Betamethasone phosphateA fast acting ester prodrug of a corticosteroid used to treat inflammatory conditions.
Dexamethasone acetateCommonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is...
Drugs & Drug Targets
DrugTargetType
Aminohippuric acidSolute carrier family 22 member 2transporter
Aminohippuric acidSolute carrier family 22 member 5transporter
Aminohippuric acidSolute carrier family 22 member 6transporter
Aminohippuric acidSolute carrier family 22 member 8transporter
Aminohippuric acidCanalicular multispecific organic anion transporter 1transporter
Aminohippuric acidSolute carrier family 22 member 4transporter
Aminohippuric acidSolute carrier family 22 member 11transporter
Aminohippuric acidSolute carrier organic anion transporter family member 3A1transporter
Aminohippuric acidSolute carrier organic anion transporter family member 1B1transporter
Aminohippuric acidMultidrug resistance-associated protein 1transporter
Aminohippuric acidSolute carrier organic anion transporter family member 1A2transporter
Aminohippuric acidMonocarboxylate transporter 1transporter
Aminohippuric acidSolute carrier family 22 member 7transporter
Glutaric AcidAspartate aminotransferasetarget
Glutaric AcidBranched-chain-amino-acid aminotransferasetarget
Glutaric AcidGlutamate decarboxylase alphatarget
Glutaric AcidSolute carrier family 22 member 6transporter
Glutaric AcidSolute carrier family 22 member 8transporter
Glutaric AcidSolute carrier family 22 member 11transporter
Glutaric AcidSolute carrier family 22 member 7transporter
AcyclovirDNA polymerase catalytic subunittarget
AcyclovirDNA polymerase catalytic subunittarget
AcyclovirThymidine kinasetarget
AcyclovirSolute carrier family 22 member 1transporter
AcyclovirSolute carrier family 22 member 6transporter
AcyclovirSolute carrier family 22 member 8transporter
AcyclovirIleal sodium/bile acid cotransportertransporter
AcyclovirMultidrug and toxin extrusion protein 1transporter
AcyclovirMultidrug and toxin extrusion protein 2transporter
AcyclovirThymidine kinaseenzyme
AcyclovirGuanylate kinaseenzyme
AcyclovirNucleoside diphosphokinaseenzyme
AcyclovirPyruvate Kinasesenzyme
AcyclovirCreatine Kinasesenzyme
AcyclovirPhosphoglycerate Kinasesenzyme
AcyclovirSuccinyl-CoA Synthetasesenzyme
AcyclovirPhosphoenolpyruvate Carboxykinasesenzyme
AcyclovirAdenylosuccinate Synthetasesenzyme
AcyclovirSerum albumincarrier
DinoprostoneProstaglandin E2 receptor EP2 subtypetarget
DinoprostoneProstaglandin E2 receptor EP1 subtypetarget
DinoprostoneProstaglandin E2 receptor EP4 subtypetarget
DinoprostoneProstaglandin E2 receptor EP3 subtypetarget
DinoprostoneSolute carrier family 22 member 2transporter
DinoprostoneMultidrug resistance-associated protein 5transporter
DinoprostoneSolute carrier family 22 member 6transporter
DinoprostoneSolute carrier family 22 member 8transporter
DinoprostoneSolute carrier family 22 member 11transporter
DinoprostoneSolute carrier family 22 member 7transporter
DinoprostoneMultidrug resistance-associated protein 4transporter
DinoprostoneSolute carrier organic anion transporter family member 2B1transporter
DinoprostoneSolute carrier organic anion transporter family member 1A2transporter
DinoprostoneOrganic solute transporter subunit alphatransporter
DinoprostoneOrganic solute transporter subunit betatransporter
DinoprostoneSolute carrier organic anion transporter family member 2A1transporter
DinoprostoneSolute carrier organic anion transporter family member 4A1transporter
DinoprostoneSolute carrier organic anion transporter family member 1C1transporter
DinoprostoneSolute carrier organic anion transporter family member 3A1transporter
DinoprostoneSolute carrier organic anion transporter family member 1B1transporter
DinoprostoneProstaglandin D2 receptor 2target
CefazolinSerum paraoxonase/arylesterase 1target
CefazolinSerum albumincarrier
CefazolinSolute carrier family 22 member 6transporter
CefazolinSolute carrier family 22 member 8transporter
CefazolinSolute carrier family 22 member 11transporter
CefazolinPenicillin-binding protein 1Atarget
CefazolinPenicillin-binding protein 1Btarget
CefazolinPenicillin-binding protein 2target
CefazolinPenicillin-binding protein 1Ctarget
CefazolinPeptidoglycan synthase FtsItarget
CefazolinMultidrug resistance-associated protein 4transporter
CefazolinThiopurine S-methyltransferaseenzyme
CefazolinInterleukin-15target
CefazolinInterleukin-2target
MethotrexateDihydrofolate reductasetarget
MethotrexateAldehyde oxidaseenzyme
MethotrexateMethylenetetrahydrofolate reductaseenzyme
MethotrexateSerum albumincarrier
MethotrexateCanalicular multispecific organic anion transporter 2transporter
MethotrexateMultidrug resistance-associated protein 4transporter
MethotrexateMultidrug resistance-associated protein 1transporter
MethotrexateSolute carrier family 22 member 6transporter
MethotrexateMultidrug resistance-associated protein 7transporter
MethotrexateSolute carrier family 22 member 8transporter
MethotrexateCanalicular multispecific organic anion transporter 1transporter
MethotrexateP-glycoprotein 1transporter
MethotrexateSolute carrier organic anion transporter family member 1A2transporter
MethotrexateMonocarboxylate transporter 1transporter
MethotrexateATP-binding cassette sub-family C member 11transporter
MethotrexateSolute carrier organic anion transporter family member 1B3transporter
MethotrexateSolute carrier family 22 member 11transporter
MethotrexateSolute carrier organic anion transporter family member 1C1transporter
MethotrexateSolute carrier organic anion transporter family member 3A1transporter
MethotrexateATP-binding cassette sub-family G member 2transporter
MethotrexateSolute carrier family 22 member 7transporter
MethotrexateSolute carrier organic anion transporter family member 1B1transporter
Methotrexate6-phosphogluconate dehydrogenase, decarboxylatingenzyme
MethotrexateProton-coupled folate transportertransporter
MethotrexateFolylpolyglutamate synthase, mitochondrialenzyme
MethotrexateGamma-glutamyl hydrolaseenzyme
MethotrexateDihydrofolate reductaseenzyme
MethotrexateThymidylate synthaseenzyme
MethotrexateBifunctional purine biosynthesis protein PURHenzyme
MethotrexateSolute carrier organic anion transporter family member 4C1transporter
MethotrexateFolate transporter 1transporter
MethotrexateFolate receptor alphatransporter
MethotrexateCytochrome P450 3A4enzyme
MethotrexateThymidylate synthasetarget
MethotrexateBifunctional purine biosynthesis protein PURHtarget
MethotrexateFolate receptor betatransporter
MethotrexateSolute carrier family 15 member 1transporter
MethotrexateProton-coupled amino acid transporter 1transporter
CephalexinSerum albumincarrier
CephalexinSolute carrier family 22 member 5transporter
CephalexinSolute carrier family 15 member 1transporter
CephalexinSolute carrier family 15 member 2transporter
CephalexinSolute carrier family 22 member 6transporter
CephalexinSolute carrier family 22 member 8transporter
CephalexinMultidrug and toxin extrusion protein 1transporter
CephalexinPenicillin-binding protein 3target
CephalexinPenicillin-binding protein 2atarget
CephalexinPenicillin-binding protein 1btarget
CephalexinPenicillin-binding protein 1Atarget
CephalexinPenicillin-binding protein 2Btarget
Taurocholic acidBile salt-activated lipasetarget
Taurocholic acidGastrotropintarget
Taurocholic acidBile salt export pumptransporter
Taurocholic acidMultidrug resistance-associated protein 1transporter
Taurocholic acidSolute carrier organic anion transporter family member 1A2transporter
Taurocholic acidIleal sodium/bile acid cotransportertransporter
Taurocholic acidCanalicular multispecific organic anion transporter 1transporter
Taurocholic acidSolute carrier organic anion transporter family member 1B1transporter
Taurocholic acidCanalicular multispecific organic anion transporter 2transporter
Taurocholic acidMultidrug resistance-associated protein 4transporter
Taurocholic acidP-glycoprotein 1transporter
Taurocholic acidSolute carrier family 22 member 6transporter
Taurocholic acidMultidrug resistance-associated protein 7transporter
Taurocholic acidSolute carrier family 22 member 8transporter
Taurocholic acidSolute carrier organic anion transporter family member 4A1transporter
Taurocholic acidATP-binding cassette sub-family C member 11transporter
Taurocholic acidSolute carrier organic anion transporter family member 1C1transporter
Taurocholic acidSolute carrier organic anion transporter family member 3A1transporter
Taurocholic acidATP-binding cassette sub-family G member 2transporter
Taurocholic acidSolute carrier organic anion transporter family member 2B1transporter
Taurocholic acidMonocarboxylate transporter 1transporter
Taurocholic acidSodium/bile acid cotransportertransporter
Taurocholic acidOrganic solute transporter subunit alphatransporter
Taurocholic acidOrganic solute transporter subunit betatransporter
Taurocholic acidSolute carrier organic anion transporter family member 1B3transporter
Taurocholic acidCystine/glutamate transportertransporter
Taurocholic acidBile acid receptortarget
Conjugated estrogensEstrogen receptor alphatarget
Conjugated estrogensCytochrome P450 3A4enzyme
Conjugated estrogensCytochrome P450 1A2enzyme
Conjugated estrogensCatechol O-methyltransferaseenzyme
Conjugated estrogensCanalicular multispecific organic anion transporter 2transporter
Conjugated estrogensMultidrug resistance-associated protein 4transporter
Conjugated estrogensMultidrug resistance-associated protein 1transporter
Conjugated estrogensSolute carrier organic anion transporter family member 1A2transporter
Conjugated estrogensSodium/bile acid cotransportertransporter
Conjugated estrogensSolute carrier family 22 member 10transporter
Conjugated estrogensSolute carrier family 22 member 8transporter
Conjugated estrogensSolute carrier organic anion transporter family member 1C1transporter
Conjugated estrogensSolute carrier organic anion transporter family member 1B1transporter
Conjugated estrogensSolute carrier organic anion transporter family member 2B1transporter
Conjugated estrogensP-glycoprotein 1transporter
Conjugated estrogensSolute carrier family 22 member 6transporter
Conjugated estrogensOrganic solute transporter subunit alphatransporter
Conjugated estrogensOrganic solute transporter subunit betatransporter
Conjugated estrogensCanalicular multispecific organic anion transporter 1transporter
Conjugated estrogensSolute carrier organic anion transporter family member 4A1transporter
Conjugated estrogensATP-binding cassette sub-family C member 11transporter
Conjugated estrogensSolute carrier organic anion transporter family member 1B3transporter
Conjugated estrogensSolute carrier family 22 member 11transporter
Conjugated estrogensSolute carrier organic anion transporter family member 3A1transporter
Conjugated estrogensATP-binding cassette sub-family G member 2transporter
Conjugated estrogensThyroxine-binding globulincarrier
Conjugated estrogensSex hormone-binding globulincarrier
Conjugated estrogensSerum albumincarrier
Conjugated estrogensEstrogen receptor betatarget
Cyclic adenosine monophosphatePotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2target
Cyclic adenosine monophosphatecAMP-dependent protein kinase type I-alpha regulatory subunittarget
Cyclic adenosine monophosphatecAMP-dependent protein kinase type II-beta regulatory subunittarget
Cyclic adenosine monophosphatecAMP-activated global transcriptional regulator CRPtarget
Cyclic adenosine monophosphateAdenylate cyclasetarget
Cyclic adenosine monophosphateCyclic nucleotide-gated potassium channel mll3241target
Cyclic adenosine monophosphateMultidrug resistance-associated protein 4transporter
Cyclic adenosine monophosphateMultidrug resistance-associated protein 5transporter
Cyclic adenosine monophosphateATP-binding cassette sub-family C member 11transporter
Cyclic adenosine monophosphateSolute carrier family 22 member 6transporter
Cyclic adenosine monophosphateSolute carrier family 22 member 8transporter
Cyclic adenosine monophosphateSolute carrier family 22 member 7transporter
CefacetrilePenicillin-binding protein 1Atarget
CefacetrilePenicillin-binding protein 1Btarget
CefacetrileSolute carrier family 22 member 6transporter
CefacetrileSolute carrier family 22 member 8transporter
Tenofovir disoproxilReverse transcriptase/RNaseHtarget
Tenofovir disoproxilSolute carrier family 22 member 6transporter
Tenofovir disoproxilSolute carrier family 22 member 8transporter
Tenofovir disoproxilMultidrug resistance-associated protein 7transporter
Tenofovir disoproxilMultidrug resistance-associated protein 4transporter
Tenofovir disoproxilCanalicular multispecific organic anion transporter 1transporter
Tenofovir disoproxilAdenylate kinase 2, mitochondrialenzyme
Tenofovir disoproxilAdenylate kinase 4, mitochondrialenzyme
Tenofovir disoproxilP-glycoprotein 1transporter
Tenofovir disoproxilNucleoside diphosphokinaseenzyme
Tenofovir disoproxilCreatine Kinasesenzyme
Tenofovir disoproxilDNA polymerase/reverse transcriptasetarget
CimetidineHistamine H2 receptortarget
CimetidineCytochrome P450 1A2enzyme
CimetidineCytochrome P450 2D6enzyme
CimetidineCytochrome P450 2C19enzyme
CimetidineCytochrome P450 3A4enzyme
CimetidineCytochrome P450 3A5enzyme
CimetidineP-glycoprotein 1transporter
CimetidineSolute carrier family 22 member 2transporter
CimetidineSolute carrier family 22 member 1transporter
CimetidineSolute carrier family 22 member 3transporter
CimetidineSolute carrier family 22 member 5transporter
CimetidineSolute carrier family 22 member 6transporter
CimetidineSolute carrier family 22 member 8transporter
CimetidineMultidrug and toxin extrusion protein 1transporter
CimetidineSolute carrier family 22 member 4transporter
CimetidineSolute carrier family 22 member 11transporter
CimetidineSolute carrier family 22 member 7transporter
CimetidineCytochrome P450 11B1, mitochondrialenzyme
CimetidineCytochrome P450 2C8enzyme
CimetidineCytochrome P450 2C9enzyme
CimetidineCytochrome P450 2E1enzyme
CimetidineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
CimetidineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
CimetidineBile salt export pumptransporter
CimetidineMultidrug and toxin extrusion protein 2transporter
BenzylpenicillinSolute carrier family 22 member 5transporter
BenzylpenicillinSolute carrier family 15 member 1transporter
BenzylpenicillinSolute carrier family 15 member 2transporter
BenzylpenicillinSolute carrier family 22 member 6transporter
BenzylpenicillinSolute carrier family 22 member 8transporter
BenzylpenicillinSolute carrier family 22 member 4transporter
BenzylpenicillinSolute carrier family 22 member 11transporter
BenzylpenicillinSolute carrier organic anion transporter family member 2B1transporter
BenzylpenicillinSolute carrier organic anion transporter family member 4A1transporter
BenzylpenicillinSolute carrier organic anion transporter family member 3A1transporter
BenzylpenicillinSolute carrier organic anion transporter family member 1B1transporter
BenzylpenicillinPenicillin-binding protein 3target
BenzylpenicillinSolute carrier family 22 member 8target
BenzylpenicillinSolute carrier family 15 member 1target
BenzylpenicillinSolute carrier family 15 member 2target
BenzylpenicillinBeta-lactamase TEMenzyme
BenzylpenicillinSerum albumincarrier
EstroneEstrogen receptor alphatarget
EstroneCytochrome P450 1A2enzyme
EstroneCytochrome P450 1A1enzyme
EstroneSerum albumincarrier
EstroneSolute carrier organic anion transporter family member 2B1transporter
EstroneP-glycoprotein 1transporter
EstroneSolute carrier organic anion transporter family member 1A2transporter
EstroneATP-binding cassette sub-family G member 2transporter
EstroneSolute carrier organic anion transporter family member 1B1transporter
EstroneCytochrome P450 3A4enzyme
EstroneCytochrome P450 1B1enzyme
EstroneCytochrome P450 2B6enzyme
EstroneCytochrome P450 2C9enzyme
EstroneCytochrome P450 2E1enzyme
EstroneCytochrome P450 3A5enzyme
EstroneEstrogen receptor betatarget
EstroneAndrogen receptortarget
EstroneCytochrome P450 19A1target
EstroneSex hormone-binding globulintarget
EstroneSolute carrier family 22 member 8transporter
Pravastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
PravastatinSolute carrier organic anion transporter family member 2B1transporter
PravastatinP-glycoprotein 1transporter
PravastatinSolute carrier organic anion transporter family member 1A2transporter
PravastatinSolute carrier family 22 member 6transporter
PravastatinSolute carrier family 22 member 8transporter
PravastatinCanalicular multispecific organic anion transporter 1transporter
PravastatinSolute carrier family 22 member 11transporter
PravastatinATP-binding cassette sub-family G member 2transporter
PravastatinSolute carrier family 22 member 7transporter
PravastatinSolute carrier organic anion transporter family member 1B1transporter
PravastatinMonocarboxylate transporter 1transporter
PravastatinBile salt export pumptransporter
PravastatinSolute carrier organic anion transporter family member 1B3transporter
PravastatinHistone deacetylase 2target
BumetanideSolute carrier family 12 member 1target
BumetanideCystic fibrosis transmembrane conductance regulatortarget
BumetanideSolute carrier family 12 member 2target
BumetanideSolute carrier family 12 member 4target
BumetanideSolute carrier family 12 member 5target
BumetanideSodium/bile acid cotransportertransporter
BumetanideSolute carrier family 22 member 6transporter
BumetanideSolute carrier family 22 member 8transporter
BumetanideSolute carrier family 22 member 11transporter
BumetanideSolute carrier family 22 member 7transporter
BumetanideSolute carrier organic anion transporter family member 1A2transporter
BumetanideProstaglandin G/H synthase 2enzyme
CaptoprilAngiotensin-converting enzymetarget
CaptoprilSerum albumincarrier
Captopril72 kDa type IV collagenasetarget
CaptoprilMatrix metalloproteinase-9target
CaptoprilP-glycoprotein 1transporter
CaptoprilSolute carrier family 15 member 1transporter
CaptoprilSolute carrier family 22 member 6transporter
CaptoprilLeukotriene A-4 hydrolasetarget
CaptoprilB1 bradykinin receptortarget
CefaclorPenicillin-binding protein 1Atarget
CefaclorSolute carrier family 15 member 1transporter
CefaclorSolute carrier family 15 member 2transporter
CefaclorPenicillin-binding protein 3target
CefaclorMyeloperoxidaseenzyme
CefaclorSolute carrier family 22 member 8transporter
CefaclorBile salt export pumptransporter
CefdinirMyeloperoxidasetarget
CefdinirPenicillin-binding protein 2target
CefdinirPBP3target
CefdinirSolute carrier family 22 member 5transporter
CefdinirSolute carrier family 15 member 1transporter
CefdinirSolute carrier family 15 member 2transporter
CefdinirSolute carrier family 22 member 6transporter
CefdinirSolute carrier family 22 member 8transporter
CefdinirPeptidoglycan transpeptidasetarget
CefotiamPenicillin-binding protein 1Atarget
CefotiamSolute carrier family 22 member 6transporter
CefotiamSolute carrier family 22 member 8transporter
CeftibutenSolute carrier family 15 member 1transporter
CeftibutenSolute carrier family 15 member 2transporter
CeftibutenPeptidoglycan synthase FtsItarget
CeftibutenPenicillin-binding protein 1Atarget
CeftibutenPenicillin-binding protein 1Btarget
CeftibutenPenicillin-binding protein 2target
CeftibutenSolute carrier family 22 member 6transporter
CeftibutenSolute carrier family 22 member 8transporter
CeftizoximeSolute carrier family 15 member 1transporter
CeftizoximePenicillin-binding protein 1Atarget
CeftizoximePenicillin-binding protein 1Btarget
CeftizoximeSolute carrier family 22 member 6transporter
CeftizoximeSolute carrier family 22 member 8transporter
CeftizoximePeptidoglycan transpeptidasetarget
CeftizoximeD-alanyl-D-alanine carboxypeptidase DacCtarget
CefaloridineSolute carrier family 22 member 6transporter
CefaloridineSolute carrier family 22 member 8transporter
Cholic AcidFerrochelatase, mitochondrialtarget
Cholic AcidBile salt export pumptransporter
Cholic AcidP-glycoprotein 1transporter
Cholic AcidMultidrug resistance-associated protein 1transporter
Cholic AcidSolute carrier organic anion transporter family member 1A2transporter
Cholic AcidIleal sodium/bile acid cotransportertransporter
Cholic AcidCanalicular multispecific organic anion transporter 1transporter
Cholic AcidSolute carrier organic anion transporter family member 1B1transporter
Cholic AcidCanalicular multispecific organic anion transporter 2transporter
Cholic AcidMultidrug resistance-associated protein 4transporter
Cholic AcidSodium/bile acid cotransportertransporter
Cholic AcidSolute carrier family 22 member 8transporter
Cholic AcidSolute carrier family 22 member 7transporter
Cholic AcidSolute carrier organic anion transporter family member 1B3transporter
Cholic AcidAlcohol dehydrogenase 1Ctarget
Cholic AcidEstrogen-related receptor gammatarget
Cholic AcidGastrotropintarget
Cholic AcidCytochrome c oxidase subunit 4 isoform 1, mitochondrialtarget
Cholic AcidCytochrome c oxidase subunit 1target
Cholic AcidCytochrome c oxidase subunit 2target
Cholic AcidCytochrome c oxidase subunit 3target
Cholic AcidCytochrome c oxidase subunit 5A, mitochondrialtarget
Cholic AcidCytochrome c oxidase subunit 5B, mitochondrialtarget
Cholic AcidCytochrome c oxidase subunit 6Ctarget
Cholic AcidCytochrome c oxidase subunit 7B, mitochondrialtarget
Cholic AcidCytochrome c oxidase subunit 7C, mitochondrialtarget
Cholic AcidCytochrome c oxidase subunit 8A, mitochondrialtarget
Cholic AcidCytochrome c oxidase subunit 6A2, mitochondrialtarget
Cholic AcidCytochrome c oxidase subunit 6B1target
Cholic AcidCytochrome c oxidase subunit 7A1, mitochondrialtarget
Cholic AcidPhospholipase A2target
Cholic AcidLiver carboxylesterase 1target
Cholic AcidFatty acid-binding protein, livercarrier
Cholic AcidFerrochelatasetarget
Cholic AcidCholoylglycine hydrolasetarget
Cholic AcidBile acid receptortarget
Cholic AcidG-protein coupled bile acid receptor 1target
HydrocortisoneAnnexin A1target
HydrocortisoneGlucocorticoid receptortarget
HydrocortisoneSex hormone-binding globulincarrier
HydrocortisoneCytochrome P450 3A4enzyme
HydrocortisoneCytochrome P450 3A5enzyme
HydrocortisoneCytochrome P450 3A7enzyme
HydrocortisoneP-glycoprotein 1transporter
HydrocortisoneSolute carrier organic anion transporter family member 1A2transporter
HydrocortisoneCytochrome P450 11B1, mitochondrialenzyme
HydrocortisoneCytochrome P450 11B2, mitochondrialenzyme
HydrocortisoneCytochrome P450 2C8enzyme
HydrocortisoneCorticosteroid-binding globulincarrier
HydrocortisoneSolute carrier family 22 member 8transporter
Hydrocortisone3-oxo-5-beta-steroid 4-dehydrogenaseenzyme
Hydrocortisone3-oxo-5-alpha-steroid 4-dehydrogenase 2enzyme
HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
HydrocortisoneCytochrome P450 2A6enzyme
HydrocortisoneCytochrome P450 1B1enzyme
HydrocortisoneCytochrome P450 2B6enzyme
HydrocortisoneCytochrome P450 2C9enzyme
HydrocortisoneCytochrome P450 2C19enzyme
EdaravoneSolute carrier family 22 member 6transporter
EdaravoneSolute carrier family 22 member 8transporter
EstradiolEstrogen receptor alphatarget
EstradiolNuclear receptor subfamily 1 group I member 2target
EstradiolSex hormone-binding globulincarrier
EstradiolEstrogen receptor betatarget
EstradiolCytochrome P450 1A2enzyme
EstradiolUDP-glucuronosyltransferase 1-1enzyme
EstradiolSerum albumincarrier
EstradiolFatty acid-binding protein, intestinalcarrier
EstradiolCytochrome P450 3A4enzyme
EstradiolCytochrome P450 3A5enzyme
EstradiolCytochrome P450 3A7enzyme
EstradiolSolute carrier family 22 member 2transporter
EstradiolSolute carrier family 22 member 3transporter
EstradiolMultidrug resistance-associated protein 7transporter
EstradiolSolute carrier family 22 member 11transporter
EstradiolATP-binding cassette sub-family G member 2transporter
EstradiolSolute carrier organic anion transporter family member 1B1transporter
EstradiolP-glycoprotein 1transporter
EstradiolCytochrome P450 1A1enzyme
EstradiolCytochrome P450 1B1enzyme
EstradiolCytochrome P450 2C19enzyme
EstradiolCytochrome P450 2C8enzyme
EstradiolCytochrome P450 2C9enzyme
EstradiolSolute carrier family 22 member 8transporter
EstradiolSolute carrier organic anion transporter family member 1B3transporter
EstradiolSolute carrier organic anion transporter family member 1C1transporter
EstradiolNeuronal acetylcholine receptor subunit alpha-4target
EstradiolG-protein coupled estrogen receptor 1target
EstradiolATP synthase subunit atarget
EstradiolBeclin-1target
EstradiolUDP-glucuronosyltransferase 2B15enzyme
EstradiolCatechol O-methyltransferaseenzyme
EstradiolUDP-glucuronosyltransferases (UGTs)enzyme
FamotidineHistamine H2 receptortarget
FamotidineSolute carrier family 22 member 2transporter
FamotidineSolute carrier family 22 member 8transporter
FamotidineMultidrug and toxin extrusion protein 1transporter
FamotidineCytochrome P450 1A2enzyme
FamotidineSolute carrier family 22 member 6transporter
FexofenadineHistamine H1 receptortarget
FexofenadineP-glycoprotein 1transporter
FexofenadineSolute carrier organic anion transporter family member 2B1transporter
FexofenadineSolute carrier organic anion transporter family member 1A2transporter
FexofenadineSolute carrier organic anion transporter family member 1B1transporter
FexofenadineSolute carrier organic anion transporter family member 1B3transporter
FexofenadineSolute carrier family 22 member 8transporter
FexofenadineCanalicular multispecific organic anion transporter 1transporter
FexofenadineCanalicular multispecific organic anion transporter 2transporter
FexofenadineSerum albumincarrier
Fexofenadinealpha1-acid glycoproteincarrier
LeucovorinSolute carrier family 22 member 8transporter
QuinaprilAngiotensin-converting enzymetarget
QuinaprilSolute carrier family 15 member 1transporter
QuinaprilSolute carrier family 15 member 2transporter
QuinaprilSolute carrier family 22 member 8transporter
QuinaprilLiver carboxylesterase 1enzyme
QuinaprilSerum albumincarrier
RanitidineHistamine H2 receptortarget
RanitidineCytochrome P450 1A2enzyme
RanitidineCytochrome P450 2D6enzyme
RanitidineSolute carrier family 22 member 1transporter
RanitidineP-glycoprotein 1transporter
RanitidineSolute carrier family 22 member 8transporter
RanitidineCytochrome P450 3A4enzyme
RanitidineAcetylcholinesterasetarget
RanitidineSolute carrier family 22 member 2transporter
RanitidineAcetylcholinesteraseenzyme
Rosuvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
RosuvastatinCytochrome P450 2C9enzyme
RosuvastatinMultidrug resistance-associated protein 4transporter
RosuvastatinSolute carrier organic anion transporter family member 1A2transporter
RosuvastatinSolute carrier organic anion transporter family member 1B3transporter
RosuvastatinSolute carrier organic anion transporter family member 2B1transporter
RosuvastatinCystine/glutamate transportertransporter
RosuvastatinSolute carrier organic anion transporter family member 1B1transporter
RosuvastatinBile salt export pumptransporter
RosuvastatinATP-binding cassette sub-family G member 2transporter
RosuvastatinSerum albumincarrier
RosuvastatinCanalicular multispecific organic anion transporter 1transporter
RosuvastatinSolute carrier family 22 member 8transporter
RosuvastatinSodium/bile acid cotransportertransporter
RosuvastatinIntegrin alpha-Ltarget
SitagliptinDipeptidyl peptidase 4target
SitagliptinCytochrome P450 3A4enzyme
SitagliptinCytochrome P450 2C8enzyme
SitagliptinP-glycoprotein 1transporter
SitagliptinSolute carrier family 22 member 8transporter
Tetracycline16S ribosomal RNAtarget
TetracyclineMajor prion proteintarget
TetracyclineSerum albumincarrier
TetracyclineCytochrome P450 3A4enzyme
TetracyclineSolute carrier family 22 member 6transporter
TetracyclineSolute carrier family 22 member 8transporter
TetracyclineSolute carrier family 22 member 11transporter
TetracyclineSolute carrier family 22 member 7transporter
Tetracycline30S ribosomal protein S3target
Tetracycline30S ribosomal protein S8target
Tetracycline30S ribosomal protein S19target
Tetracycline30S ribosomal protein S14target
Tetracycline30S ribosomal protein S7target
TetracyclineMultidrug translocase MdfAtarget
TetracyclineProtein-arginine deiminase type-4target
TetracyclineSolute carrier organic anion transporter family member 2B1transporter
ValaciclovirThymidine kinasetarget
ValaciclovirDNA polymerase catalytic subunittarget
ValaciclovirSolute carrier family 15 member 1transporter
ValaciclovirSolute carrier family 15 member 2transporter
ValaciclovirSolute carrier family 22 member 8transporter
ValaciclovirSolute carrier family 22 member 6transporter
ValaciclovirSodium- and chloride-dependent neutral and basic amino acid transporter B(0+)transporter
ValaciclovirIleal sodium/bile acid cotransportertransporter
ValaciclovirGuanylate kinaseenzyme
ValaciclovirThymidine kinaseenzyme
ZidovudineSerum albumincarrier
ZidovudineCytochrome P450 2A6enzyme
ZidovudineCytochrome P450 2C9enzyme
ZidovudineCytochrome P450 3A4enzyme
ZidovudineReverse transcriptase/RNaseHtarget
ZidovudineSolute carrier family 22 member 2transporter
ZidovudineSolute carrier family 22 member 6transporter
ZidovudineSolute carrier family 22 member 7transporter
ZidovudineSolute carrier family 22 member 8transporter
ZidovudineSolute carrier family 22 member 11transporter
ZidovudineSodium/nucleoside cotransporter 1transporter
ZidovudineEquilibrative nucleoside transporter 2transporter
ZidovudineP-glycoprotein 1transporter
ZidovudineMultidrug resistance-associated protein 4transporter
ZidovudineMultidrug resistance-associated protein 5transporter
ZidovudineATP-binding cassette sub-family G member 2transporter
ZidovudineTelomerase reverse transcriptasetarget
ZidovudineThymidine kinase, cytosolicenzyme
ZidovudineUDP-glucuronosyltransferase 2B7enzyme
ZidovudineUDP-glucuronosyltransferase 1-1enzyme
IndomethacinProstaglandin G/H synthase 1target
IndomethacinProstaglandin G/H synthase 2target
IndomethacinCytochrome P450 2C19enzyme
IndomethacinUDP-glucuronosyltransferase 1-9enzyme
IndomethacinPhospholipase A2, membrane associatedtarget
IndomethacinProstaglandin reductase 2target
IndomethacinLactoylglutathione lyasetarget
IndomethacinProstaglandin D2 receptor 2target
IndomethacinPeroxisome proliferator-activated receptor gammatarget
IndomethacinSerum albumincarrier
IndomethacinCanalicular multispecific organic anion transporter 2transporter
IndomethacinMultidrug resistance-associated protein 4transporter
IndomethacinMultidrug resistance-associated protein 6transporter
IndomethacinP-glycoprotein 1transporter
IndomethacinMultidrug resistance-associated protein 1transporter
IndomethacinSolute carrier organic anion transporter family member 1A2transporter
IndomethacinSolute carrier family 22 member 6transporter
IndomethacinSolute carrier family 22 member 8transporter
IndomethacinCanalicular multispecific organic anion transporter 1transporter
IndomethacinATP-binding cassette sub-family C member 11transporter
IndomethacinSolute carrier family 22 member 11transporter
IndomethacinSodium/bile acid cotransportertransporter
IndomethacinSolute carrier family 22 member 7transporter
IndomethacinCytochrome P450 2C9enzyme
IndomethacinUDP-glucuronosyltransferase 1-1enzyme
IndomethacinLiver carboxylesterase 1enzyme
IndomethacinUDP-glucuronosyltransferase 2B7enzyme
IndomethacinPeroxisome proliferator-activated receptor alphatarget
IndomethacinAldo-keto reductase family 1 member C3target
IndomethacinSolute carrier organic anion transporter family member 1B1transporter
IndomethacinBile salt export pumptransporter
FluoresceinIg kappa chain V-II region RPMI 6410target
FluoresceinDNAtarget
FluoresceinSolute carrier family 22 member 6transporter
FluoresceinBile salt export pumptransporter
FluoresceinMultidrug resistance-associated protein 1transporter
TrifluridineThymidylate synthasetarget
TrifluridineDNAtarget
TrifluridineThymidine kinase, cytosolicenzyme
TrifluridineThymidine phosphorylaseenzyme
TrifluridineSolute carrier family 22 member 6transporter
TrifluridineSodium/nucleoside cotransporter 1transporter
TrifluridineEquilibrative nucleoside transporter 1transporter
TrifluridineEquilibrative nucleoside transporter 2transporter
TrifluridineSerum albumincarrier
Ellagic acidSolute carrier family 22 member 6transporter
Ellagic acidSolute carrier family 22 member 11transporter
Ellagic acidCytochrome P450 1A1enzyme
Ellagic acidCytochrome P450 2E1enzyme
Ellagic acidCarbonic anhydrase 1target
Ellagic acidCarbonic anhydrase 2target
Ellagic acidCarbonic anhydrase 3target
Ellagic acidCarbonic anhydrase 4target
Ellagic acidCarbonic anhydrase 5A, mitochondrialtarget
Ellagic acidCarbonic anhydrase 5B, mitochondrialtarget
Ellagic acidCarbonic anhydrase 6target
Ellagic acidCarbonic anhydrase 7target
Ellagic acidCarbonic anhydrase 9target
Ellagic acidCarbonic anhydrase 12target
Ellagic acidCarbonic anhydrase 14target
Ellagic acidCasein kinase II subunit alphatarget
Ellagic acidcAMP-dependent protein kinase catalytic subunit alphatarget
Ellagic acidProtein kinase C alpha typetarget
Ellagic acidProtein kinase C beta typetarget
Ellagic acidTyrosine-protein kinase SYKtarget
Ellagic acidSqualene monooxygenasetarget
CitrullineNitric oxide synthase, endothelialtarget
CitrullineArgininosuccinate synthasetarget
CitrullineN(G),N(G)-dimethylarginine dimethylaminohydrolase 2target
CitrullineArgininosuccinate synthetase, isoform CRA_atarget
CitrullineN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
CitrullineOrnithine carbamoyltransferase, mitochondrialtarget
CitrullineNitric oxide synthase, braintarget
CitrullineNitric oxide synthase, inducibletarget
CitrullineProtein-arginine deiminase type-4target
CitrullineProtein-arginine deiminase type-6target
CitrullineProtein-arginine deiminase type-1target
CitrullineProtein-arginine deiminase type-3target
CitrullineProtein-arginine deiminase type-2target
CitrullineSolute carrier family 22 member 6transporter
AlprostadilProstaglandin E2 receptor EP2 subtypetarget
AlprostadilProstaglandin E2 receptor EP1 subtypetarget
AlprostadilMultidrug resistance-associated protein 5transporter
AlprostadilSolute carrier organic anion transporter family member 2B1transporter
AlprostadilSolute carrier organic anion transporter family member 3A1transporter
AlprostadilMultidrug resistance-associated protein 4transporter
AlprostadilSolute carrier organic anion transporter family member 2A1transporter
AlprostadilProstaglandin D2 receptor 2target
AlprostadilSolute carrier family 22 member 6transporter
SilibininSolute carrier family 22 member 6transporter
SilibininUDP-glucuronosyltransferase 1-1enzyme
SilibininSolute carrier organic anion transporter family member 1B1transporter
SilibininSolute carrier organic anion transporter family member 1B3transporter
SilibininSolute carrier organic anion transporter family member 2B1transporter
PiperacillinSolute carrier family 22 member 6transporter
PiperacillinPenicillin-binding protein 3target
PiperacillinPenicillin-binding protein 2Btarget
PiperacillinPenicillin-binding protein 2atarget
PiperacillinPenicillin-binding protein 1btarget
PiperacillinSolute carrier family 22 member 8transporter
TazobactamBeta-lactamase TEMtarget
TazobactamSolute carrier family 22 member 6transporter
TazobactamSolute carrier family 22 member 8transporter
TazobactamBeta-lactamase Ohio-1target
TazobactamBeta-lactamase SHV-1target
Valproic acidHistone deacetylase 9target
Valproic acidShort/branched chain specific acyl-CoA dehydrogenase, mitochondrialtarget
Valproic acidCytochrome P450 2A6enzyme
Valproic acidCytochrome P450 2B6enzyme
Valproic acidCytochrome P450 2C9enzyme
Valproic acidSolute carrier family 22 member 5transporter
Valproic acidSolute carrier family 22 member 6transporter
Valproic acidSolute carrier family 22 member 8transporter
Valproic acidMonocarboxylate transporter 1transporter
Valproic acidSolute carrier family 22 member 7transporter
Valproic acidCytochrome P450 3A5enzyme
Valproic acidUDP-glucuronosyltransferase 1-9enzyme
Valproic acidProstaglandin G/H synthase 1enzyme
Valproic acidCytochrome P450 1A2enzyme
Valproic acidCytochrome P450 2C19enzyme
Valproic acidCytochrome P450 3A4enzyme
Valproic acidUDP-glucuronosyltransferase 1-4enzyme
Valproic acidUDP-glucuronosyltransferase 1-8enzyme
Valproic acidUDP-glucuronosyltransferase 1-10enzyme
Valproic acidUDP-glucuronosyltransferase 1-6enzyme
Valproic acidUDP-glucuronosyltransferase 1-3enzyme
Valproic acidUDP-glucuronosyltransferase 2B7enzyme
Valproic acidUDP-glucuronosyltransferase 2B15enzyme
Valproic acid2-oxoglutarate dehydrogenase, mitochondrialtarget
Valproic acidSuccinate-semialdehyde dehydrogenase, mitochondrialtarget
Valproic acidSodium channel proteintarget
Valproic acidHistone deacetylase 2target
Valproic acidPeroxisome proliferator-activated receptor alphatarget
Valproic acidPeroxisome proliferator-activated receptor deltatarget
Valproic acidPeroxisome proliferator-activated receptor gammatarget
Valproic acidSerum albumincarrier
Valproic acidUDP-glucuronosyltransferase 1-1enzyme
Valproic acidSolute carrier organic anion transporter family member 2B1transporter
MercaptopurineThiopurine S-methyltransferaseenzyme
MercaptopurineXanthine dehydrogenase/oxidaseenzyme
MercaptopurineHypoxanthine-guanine phosphoribosyltransferasetarget
MercaptopurineSolute carrier family 22 member 8transporter
MercaptopurineMultidrug resistance-associated protein 4transporter
MercaptopurineMultidrug resistance-associated protein 5transporter
MercaptopurineSodium/nucleoside cotransporter 2transporter
MercaptopurineSolute carrier family 28 member 3transporter
MercaptopurineEquilibrative nucleoside transporter 1transporter
MercaptopurineEquilibrative nucleoside transporter 2transporter
MercaptopurineAldehyde oxidaseenzyme
MercaptopurineAmidophosphoribosyltransferasetarget
MercaptopurineInosine-5'-monophosphate dehydrogenasetarget
Succinic acidSuccinate-semialdehyde dehydrogenase, mitochondrialtarget
Succinic acidSuccinate receptor 1target
Succinic acidSolute carrier family 22 member 8transporter
Succinic acidSuccinate dehydrogenase cytochrome b560 subunit, mitochondrialenzyme
Succinic acidSuccinyl-CoA ligase [GDP-forming] subunit beta, mitochondrialenzyme
Succinic acidSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialenzyme
Succinic acidMitochondrial dicarboxylate carriertransporter
Succinic acidProlyl 4-hydroxylaseenzyme
Succinic acidProcollagen-lysine,2-oxoglutarate 5-dioxygenase 3enzyme
Succinic acidSolute carrier family 13 member 1transporter
Succinic acidSolute carrier family 13 member 2transporter
Succinic acidSolute carrier family 13 member 3transporter
Succinic acidProlyl 3-hydroxylase 1enzyme
Succinic acidProlyl 3-hydroxylase 2enzyme
Succinic acidProlyl 3-hydroxylase 3enzyme
Succinic acidSuccinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrialenzyme
Succinic acidAspartyl/asparaginyl beta-hydroxylaseenzyme
Oxalic AcidProto-oncogene tyrosine-protein kinase Srctarget
Oxalic AcidSolute carrier organic anion transporter family member 2B1transporter
Oxalic AcidSolute carrier family 22 member 8transporter
LevocarnitineCarnitine O-palmitoyltransferase 1, liver isoformtarget
LevocarnitineSolute carrier family 22 member 4target
LevocarnitineSolute carrier family 22 member 5target
LevocarnitineCarnitine O-acetyltransferasetarget
LevocarnitineMitochondrial carnitine/acylcarnitine carrier protein CACLtarget
LevocarnitineMitochondrial carnitine/acylcarnitine carrier proteintarget
LevocarnitinePeroxisomal carnitine O-octanoyltransferasetarget
LevocarnitineCarnitine O-palmitoyltransferase 2, mitochondrialtarget
LevocarnitineSolute carrier family 22 member 4transporter
LevocarnitineSolute carrier organic anion transporter family member 1B1transporter
LevocarnitineSolute carrier family 22 member 5transporter
LevocarnitineSolute carrier family 22 member 16transporter
LevocarnitineSolute carrier family 22 member 8transporter
LevocarnitineXanthine dehydrogenase/oxidasetarget
LevocarnitineLiver carboxylesterase 1target
LevocarnitineMyeloperoxidasetarget
AllopurinolXanthine dehydrogenase/oxidasetarget
AllopurinolSolute carrier family 22 member 8transporter
AllopurinolSolute carrier family 22 member 7transporter
AllopurinolAldehyde oxidaseenzyme
AllopurinolXanthine dehydrogenase/oxidaseenzyme
AllopurinolATP-binding cassette sub-family G member 2transporter
AllopurinolSolute carrier family 22 member 2transporter
OseltamivirNeuraminidasetarget
OseltamivirSialidase-1target
OseltamivirSialidase-2target
OseltamivirMultidrug resistance-associated protein 4transporter
OseltamivirSolute carrier family 15 member 1transporter
OseltamivirSolute carrier family 22 member 8transporter
OseltamivirLiver carboxylesterase 1enzyme
SaxagliptinDipeptidyl peptidase 4target
SaxagliptinCytochrome P450 3A4enzyme
SaxagliptinCytochrome P450 3A5enzyme
SaxagliptinMultidrug resistance-associated protein 1transporter
SaxagliptinSolute carrier organic anion transporter family member 4C1transporter
SaxagliptinSolute carrier family 22 member 8transporter
EluxadolineMu-type opioid receptortarget
EluxadolineDelta-type opioid receptortarget
EluxadolineKappa-type opioid receptortarget
EluxadolineSolute carrier organic anion transporter family member 1B1transporter
EluxadolineCanalicular multispecific organic anion transporter 1transporter
EluxadolineSolute carrier family 22 member 8transporter
AvibactamCanalicular multispecific organic anion transporter 1transporter
AvibactamSolute carrier family 22 member 8transporter
AvibactamBeta-lactamase TEMtarget
AvibactamBeta-lactamase CTX-Mtarget
AvibactamBeta-lactamasetarget
AvibactamBeta-lactamase SHV-1target
AvibactamBeta-lactamase SHV-2target
AvibactamBeta-lactamase SHV-1target
AvibactamClass D OXA-48 carbapenemasetarget
AvibactamCarbapenem-hydrolyzing beta-lactamase KPCtarget
AvibactamBeta-lactamase CTX-M-15target
AvibactamExtended-spectrum beta-lactamase PER-1target
BaricitinibSolute carrier family 22 member 8transporter
BaricitinibATP-binding cassette sub-family G member 2transporter
BaricitinibMultidrug and toxin extrusion protein 2transporter
BaricitinibCytochrome P450 3A4enzyme
BaricitinibTyrosine-protein kinase JAK1target
BaricitinibTyrosine-protein kinase JAK2target
BaricitinibSolute carrier family 22 member 6transporter
BaricitinibSolute carrier family 22 member 2transporter
BaricitinibSolute carrier organic anion transporter family member 1B3transporter
BaricitinibProtein-tyrosine kinase 2-betatarget
BaricitinibTyrosine-protein kinase JAK3target
BaricitinibP-glycoprotein 1transporter
PemetrexedThymidylate synthasetarget
PemetrexedDihydrofolate reductasetarget
PemetrexedTrifunctional purine biosynthetic protein adenosine-3target
PemetrexedDeoxycytidine kinaseenzyme
PemetrexedBifunctional purine biosynthesis protein PURHtarget
PemetrexedEquilibrative nucleoside transporter 1enzyme
PemetrexedSolute carrier family 22 member 8transporter
DoripenemDipeptidase 1enzyme
DoripenemPenicillin-binding protein 1Atarget
DoripenemPenicillin-binding protein 1Btarget
DoripenemPenicillin-binding protein 2target
DoripenemPenicillin-binding protein 3target
DoripenemPenicillin-binding protein 4target
DoripenemSolute carrier family 22 member 8transporter
Tenofovir alafenamideReverse transcriptase/RNaseHtarget
Tenofovir alafenamideP-glycoprotein 1transporter
Tenofovir alafenamideMultidrug resistance-associated protein 4transporter
Tenofovir alafenamideSolute carrier family 22 member 6transporter
Tenofovir alafenamideSolute carrier family 22 member 8transporter
Tenofovir alafenamideLysosomal protective proteinenzyme
Tenofovir alafenamideLiver carboxylesterase 1enzyme
Tenofovir alafenamideATP-binding cassette sub-family G member 2transporter
Tenofovir alafenamideSolute carrier organic anion transporter family member 1B1transporter
Tenofovir alafenamideSolute carrier organic anion transporter family member 1B3transporter
Tenofovir alafenamideReverse transcriptasetarget
Tenofovir alafenamideDNA polymerasetarget
Tenofovir alafenamideSerum albumincarrier
Tenofovir alafenamideCytochrome P450 3A4enzyme
Tenofovir alafenamideAdenylate kinase isoenzyme 1enzyme
Tenofovir alafenamideAdenylate kinase 2, mitochondrialenzyme
Tenofovir alafenamideNucleoside diphosphate kinase Aenzyme
Tenofovir alafenamideNucleoside diphosphate kinase Benzyme
TenofovirP-glycoprotein 1transporter
TenofovirSolute carrier family 22 member 6transporter
TenofovirSolute carrier family 22 member 8transporter
TenofovirMultidrug resistance-associated protein 4transporter
TenofovirCytochrome P450 3A4enzyme
TenofovirNucleoside diphosphate kinase Aenzyme
TenofovirNucleoside diphosphate kinase Benzyme
TenofovirAdenylate kinase isoenzyme 1enzyme
TenofovirAdenylate kinase 2, mitochondrialenzyme
TenofovirReverse transcriptase/RNaseHtarget
TenofovirReverse transcriptasetarget
TenofovirDNA polymerasetarget
TenofovirSerum albumincarrier
RelebactamSolute carrier family 22 member 8transporter
RelebactamSolute carrier family 22 member 11transporter
RelebactamMultidrug and toxin extrusion protein 1transporter
RelebactamMultidrug and toxin extrusion protein 2transporter
RelebactamBeta-lactamase TEMtarget
RelebactamBeta-lactamase SHV-1target
RelebactamBeta-lactamase CTX-Mtarget
RelebactamBeta-lactamase (KPC-2)target
RelebactamBeta-lactamasetarget
HydrochlorothiazideSolute carrier family 12 member 3target
HydrochlorothiazideSolute carrier family 22 member 6transporter
HydrochlorothiazideCalcium-activated potassium channel subunit alpha-1target
HydrochlorothiazideSerum albumincarrier
HydrochlorothiazideSolute carrier family 22 member 11transporter
HydrochlorothiazideMultidrug resistance-associated protein 4transporter
HydrochlorothiazideSolute carrier family 22 member 8transporter
BudesonideGlucocorticoid receptortarget
BudesonideCytochrome P450 3A4enzyme
BudesonideCytochrome P450 3A5enzyme
BudesonideBile salt export pumptransporter
BudesonideP-glycoprotein 1transporter
BudesonideAnnexin A1target
BudesonideCytochrome P450 3A Subfamilyenzyme
BudesonideCytochrome P450 2A6enzyme
BudesonideCytochrome P450 1B1enzyme
BudesonideCytochrome P450 2B6enzyme
BudesonideCytochrome P450 2C8enzyme
BudesonideCytochrome P450 2C9enzyme
BudesonideCytochrome P450 2C19enzyme
BudesonideCorticosteroid-binding globulincarrier
BudesonideSolute carrier organic anion transporter family member 1A2transporter
BudesonideSolute carrier family 22 member 8transporter
BudesonideSerum albumincarrier
DexamethasoneGlucocorticoid receptortarget
DexamethasoneAnnexin A1target
DexamethasoneNitric oxide synthase, inducibletarget
DexamethasoneNuclear receptor subfamily 0 group B member 1target
DexamethasoneCytochrome P450 3A4enzyme
DexamethasoneCytochrome P450 3A5enzyme
DexamethasoneCytochrome P450 3A7enzyme
DexamethasoneBile salt export pumptransporter
DexamethasoneP-glycoprotein 1transporter
DexamethasoneCanalicular multispecific organic anion transporter 1transporter
DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DexamethasoneATP-binding cassette sub-family G member 2transporter
DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DexamethasoneCytochrome P450 1A1enzyme
DexamethasoneCytochrome P450 2A6enzyme
DexamethasoneCytochrome P450 2B6enzyme
DexamethasoneCytochrome P450 2C19enzyme
DexamethasoneCytochrome P450 2C8enzyme
DexamethasoneCytochrome P450 2E1enzyme
DexamethasoneCytochrome P450 3A43enzyme
DexamethasoneCytochrome P450 4A11enzyme
DexamethasoneNuclear receptor subfamily 1 group I member 2target
DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DexamethasoneSerum albumincarrier
DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DexamethasoneSolute carrier family 22 member 8transporter
Oxytetracycline30S ribosomal protein S4target
Oxytetracycline30S ribosomal protein S9target
Oxytetracycline16S ribosomal RNAtarget
OxytetracyclineSolute carrier family 22 member 6transporter
OxytetracyclineSolute carrier family 22 member 8transporter
OxytetracyclineSolute carrier family 22 member 11transporter
OxytetracyclineSolute carrier family 22 member 7transporter
OxytetracyclineSerum albumincarrier
MedrysoneCorticosteroid-binding globulincarrier
MedrysoneGlucocorticoid receptortarget
MedrysoneCytochrome P450 3A4enzyme
MedrysoneCytochrome P450 3A5enzyme
MedrysoneSolute carrier organic anion transporter family member 1A2transporter
MedrysoneP-glycoprotein 1transporter
MedrysoneSolute carrier family 22 member 8transporter
HydroflumethiazideSolute carrier family 12 member 1target
HydroflumethiazideSodium/potassium-transporting ATPase subunit alpha-1target
HydroflumethiazideCarbonic anhydrase 4target
HydroflumethiazideCalcium-activated potassium channel subunit alpha-1target
HydroflumethiazideCarbonic anhydrase 2target
HydroflumethiazideCarbonic anhydrase 1target
HydroflumethiazideCarbonic anhydrase 9target
HydroflumethiazideCarbonic anhydrase 12target
HydroflumethiazideSerum albumincarrier
HydroflumethiazideSolute carrier family 22 member 6transporter
HydroflumethiazideSolute carrier family 22 member 8transporter
HydroflumethiazideCarbonic anhydrase 7target
PolythiazideSolute carrier family 12 member 3target
PolythiazideSolute carrier family 22 member 6transporter
PolythiazideSolute carrier family 22 member 8transporter
PolythiazideSerum albumincarrier
Prednisolone phosphateCytochrome P450 3A4enzyme
Prednisolone phosphateCytochrome P450 3A5enzyme
Prednisolone phosphateCytochrome P450 3A Subfamilyenzyme
Prednisolone phosphateCytochrome P450 2A6enzyme
Prednisolone phosphateCytochrome P450 1B1enzyme
Prednisolone phosphateCytochrome P450 2B6enzyme
Prednisolone phosphateCytochrome P450 2C8enzyme
Prednisolone phosphateCytochrome P450 2C9enzyme
Prednisolone phosphateCytochrome P450 2C19enzyme
Prednisolone phosphateCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
Prednisolone phosphateCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
Prednisolone phosphateGlucocorticoid receptortarget
Prednisolone phosphateAnnexin A1target
Prednisolone phosphateSolute carrier organic anion transporter family member 1A2transporter
Prednisolone phosphateP-glycoprotein 1transporter
Prednisolone phosphateSolute carrier family 22 member 8transporter
Prednisolone phosphateCorticosteroid-binding globulincarrier
Prednisolone phosphateSerum albumincarrier
ClofarabineDNA polymerase alpha catalytic subunittarget
ClofarabineRibonucleoside-diphosphate reductase large subunittarget
ClofarabineDeoxycytidine kinaseenzyme
ClofarabineDNAtarget
ClofarabineATP-binding cassette sub-family G member 2transporter
EmpagliflozinSodium/glucose cotransporter 2target
EmpagliflozinUDP-glucuronosyltransferase 2B7enzyme
EmpagliflozinUDP-glucuronosyltransferase 1-3enzyme
EmpagliflozinUDP-glucuronosyltransferase 1-8enzyme
EmpagliflozinUDP-glucuronosyltransferase 1-9enzyme
EmpagliflozinP-glycoprotein 1transporter
EmpagliflozinATP-binding cassette sub-family G member 2transporter
EmpagliflozinSolute carrier family 22 member 8transporter
EmpagliflozinSolute carrier organic anion transporter family member 1B1transporter
EmpagliflozinSolute carrier organic anion transporter family member 1B3transporter
Betamethasone phosphateCytochrome P450 3A4enzyme
Betamethasone phosphateCytochrome P450 3A5enzyme
Betamethasone phosphateGlucocorticoid receptortarget
Betamethasone phosphateAnnexin A1target
Betamethasone phosphateCorticosteroid-binding globulincarrier
Betamethasone phosphateSerum albumincarrier
Betamethasone phosphateSolute carrier organic anion transporter family member 1A2transporter
Betamethasone phosphateP-glycoprotein 1transporter
Betamethasone phosphateSolute carrier family 22 member 8transporter
Dexamethasone acetateGlucocorticoid receptortarget
Dexamethasone acetateAnnexin A1target
Dexamethasone acetateNitric oxide synthase, inducibletarget
Dexamethasone acetateNuclear receptor subfamily 0 group B member 1target
Dexamethasone acetateCytochrome P450 3A4enzyme
Dexamethasone acetateCytochrome P450 3A5enzyme
Dexamethasone acetateCytochrome P450 3A7enzyme
Dexamethasone acetateBile salt export pumptransporter
Dexamethasone acetateP-glycoprotein 1transporter
Dexamethasone acetateCanalicular multispecific organic anion transporter 1transporter
Dexamethasone acetateSolute carrier organic anion transporter family member 1A2transporter
Dexamethasone acetateATP-binding cassette sub-family G member 2transporter
Dexamethasone acetateSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
Dexamethasone acetateCytochrome P450 1A1enzyme
Dexamethasone acetateCytochrome P450 2A6enzyme
Dexamethasone acetateCytochrome P450 2B6enzyme
Dexamethasone acetateCytochrome P450 2C19enzyme
Dexamethasone acetateCytochrome P450 2C8enzyme
Dexamethasone acetateCytochrome P450 2E1enzyme
Dexamethasone acetateCytochrome P450 3A43enzyme
Dexamethasone acetateCytochrome P450 4A11enzyme
Dexamethasone acetateNuclear receptor subfamily 1 group I member 2target
Dexamethasone acetateCytochrome P450 11B1, mitochondrialenzyme
Dexamethasone acetateSerum albumincarrier
Dexamethasone acetateCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
Dexamethasone acetateCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
Dexamethasone acetateSolute carrier family 22 member 8transporter