OAT3/SLC22A8 Inhibitors

Name
OAT3/SLC22A8 Inhibitors
Accession Number
DBCAT003946
Description

Drugs which inhibit organic anion transporter 3.

Drugs
DrugDrug Description
IvosidenibAn isocitrate dehydrogenase-1 inhibitor used to treat acute myeloid leukemia with a susceptible mutation.
LenvatinibA receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma.
TeriflunomideA pyrimidine synthesis inhibitor with anti-inflammatory and immunomodulatory properties used to treat patients with the relapsing-remitting form of multiple sclerosis.
ProbenecidA medication used to treat gouty arthritis, tophaceous gout, and hyperuricemia.
Taurocholic acidThe product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats...
Salicylic acidAn acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.
QuinidineA medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
BenzylpenicillinA penicillin used for the treatment of infections caused by gram-positive cocci, in particular streptococcal infections. This form of penicillin is typically used in intravenous or long-acting injectable formulations due to poor oral absorption.
OuabainFor the treatment of atrial fibrillation and flutter and heart failure
IndomethacinA nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
IbuprofenAn NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.
GuanidineA strong organic base used to treat muscle weakness and fatigue associated with the myasthenic complications of Eaton-Lambert syndrome.
Glutaric AcidNot Available
FurosemideA loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension.
DiclofenacAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
Cholic AcidA bile acid used for the treatment of bile acid synthesis disorders due to single enzyme defects and as an adjunctive treatment of peroxisomal disorders with disrupted liver function.
BumetanideA sulfamyl diuretic used to treat edema in congestive heart failure, hepatic and renal disease, and nephrotic syndrome.
CilastatinA renal dehydropeptidase inhibitor used to prevent degradation of imipenem. Both medications are used together to treat a variety of infections.
PiroxicamAn NSAID used to treat the symptoms of osteoarthritis and rheumatoid arthritis.
Aminohippuric acidA hippuric acid derivative injection utilized in the measurement of effective renal plasma flow (ERPF) and functional capacity of the renal excretory system.
Caprylic acidCaprylic acid is an eight-carbon chain fatty acid, also known systematically as octanoic acid. It is found naturally in coconuts and breast milk. It is an oily liquid with a...
CimetidineA histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion.
AspartameUsed as a diet supplement and sugar substitute.
TetracyclineAn antibiotic used to treat a wide variety of susceptible infections.
OxytetracyclineA tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections.
MinocyclineA tetracycline analog used to treat a wide variety of infections in the body.
GanciclovirA DNA polymerase inhibitor used to treat cytomegalovirus and herpetic keratitis of the eye.
AcyclovirA guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster.
DinoprostoneA prostaglandin used to induce labor or abortion as well as to treat nonmetastatic gestational trophoblastic disease.
CefalotinA broad-spectrum cephalosporin antibiotic used for the treatment of serious bacterial infections in various locations, such as the urinary tract, skin, bone, and lower respiratory tract.
CefoperazoneA broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, including the respiratory tract, abdomen, skin, and female genital tracts.
CefazolinA broad-spectrum cephalosporin antibiotic mainly used for the treatment of skin bacterial infections and other moderate to severe bacterial infections in the lung, bone, joint, stomach, blood, heart valve, and urinary tract.
CefamandoleA beta-lactam antibiotic used in the treatment of various infections caused by susceptible strains of bacteria, such as lower respiratory infections, urinary tract infections, skin infections, and bone and joint infections.
CefadroxilA cephalosporin antibiotic used in the treatment of various bacterial infections, such as urinary tract infections, skin and skin structure infections, and tonsillitis.
CeftriaxoneA broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections at various locations, such as in the respiratory tract, skin, soft tissue, and urinary tract.
CefotaximeA third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections.
PhenylbutazoneAn NSAID used to treat backache and ankylosing spondylitis.
KetoprofenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain.
FamotidineA histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome.
LiothyronineA thyroid hormone replacement therapy used to treat hypothyroidism, to suppress TSH, and to help in the diagnosis of hyperthyroidism.
MethotrexateAn antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis.
Conjugated estrogensA mixture of estrogens used in estrogen replacement therapy for menopause and hypoestrogenism, used in the treatment of various malignancies, and used in the treatment of postmenopausal osteoporosis.
TenoxicamAn anti inflammatory analgesic used to treat mild to moderate pain as well as the signs and symptoms of rheumatoid arthritis and osteoarthritis.
EnalaprilA prodrug of an ACE inhibitor used to treat hypertension and congestive heart failure.
trans-2-hydroxycinnamic acidNot Available
CephalexinA first generation cephalosporin used to treat certain susceptible bacterial infections.
Valproic acidAn anticonvulsant used to control complex partial seizures and both simple and complex absence seizures.
MelatoninAn endogenous hormone produced by the pineal gland that regulates sleep-wake cycles and when provided exogenously has beneficial effects on sleep-onset latency; available as an over-the-counter supplement.
Benzoic acidAn antimicrobial food additive.
MercaptopurineAn antineoplastic agent used to treat acute lymphocytic leukemia.
NovobiocinFor the treatment of infections due to staphylococci and other susceptible organisms
LiotrixMay be used to treat primary, secondary or tertiary hypothyroidism. May also be used to suppress thyroid stimulating hormone (TSH) secretion in patients with simple (nontoxic) goiter, subacute or chronic...
CefacetrileCefacetrile is a broad-spectrum first generation cephalosporin antibiotic effective in Gram-positive and Gram-negative bacterial infections.
ZidovudineA dideoxynucleoside used in the treatment of HIV infection.
DabrafenibA kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.
TopiroxostatIndicated for the treatment of gout and hyperurcemia in Japan.
AtalurenA medication used for the treatment of Duchenne muscular dystrophy.
EnasidenibAn isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation.
LetermovirAn antiviral medication used to treat CMV infections and disease in adult CMV-seropositive recipients of an allogeneic hematopoietic stem cell transplant (HSCT).
DolutegravirAn antiviral agent used for the treatment of HIV-1 infections in combination with other antiretroviral agents.
RucaparibAn anti-cancer agent used to treat recurrent ovarian, fallopian tube, or peritoneal cancer.
BaricitinibA Janus kinase inhibitor used to treat moderate to severe rheumatoid arthritis that has responded poorly to at least one TNF antagonist.
ApalutamideAn androgen receptor inhibitor used to treat non metastatic, castration resistant prostate cancer.
AvatrombopagA thrombopoietin receptor agonist used to treat thrombocytopenia in patients with chronic liver disease who are scheduled to undergo a procedure.
CefaclorA second generation cephalosporin used to treat a wide variety of infections in the body.
CefotiamFor treatment of severe infections caused by susceptible bacteria.
CeftibutenA third-generation cephalosporin antibiotic commonly used in the treatment of acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsillitis.
CeftizoximeA third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including lower respiratory tract infection, urinary tract infection, and gonorrhea.
CefaloridineCephaloridine or cefaloridine is a first generation semisynthetic cephalosporin. It is derived from cephalosporin C and is a zwitterion at physiological pH.
LeucovorinA folate analog used to treat the toxic effects of methotrexate and other folate antagonists, to treat megaloblastic anemia, and to provide palliative treatment of colorectal cancer.
RosuvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
RifampicinAn antibiotic used to treat several types of mycobacterial infections including Mycobacterium avium complex, leprosy, and in combination with other antibacterials to treat latent or active tuberculosis.
CabotegravirCabotegravir has been investigated for the treatment of Acquired Immunodeficiency Syndrome.
PradigastatPradigastat has been used in trials studying the treatment of Non-alcoholic Fatty Liver Disease (NAFLD).
LansoprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
PantoprazoleA proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid.
EsomeprazoleA proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion.
PravastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and to reduce the risk of cardiovascular events, including myocardial infarction and stroke.
TazobactamA beta lactamase inhibitor administered with antibiotics such as piperacillin and ceftolozane to prevent their degradation, resulting in increased efficacy.
PretomanidPart of a three-drug regimen used for the treatment of extensively drug-resistant and multidrug-resistant pulmonary tuberculosis.
LatanoprostAn isopropyl ester prodrug used to treat increased intraocular pressure.
GemfibrozilA lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia.
DronedaroneAn antiarrhythmic agent used in the reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation.
TafamidisA medication used to treat transthyretin-mediated amyloidosis.
RimegepantAn oral CGRP receptor antagonist used for the acute treatment of migraines with or without aura in adults.
FavipiravirAn antiviral used to manage influenza, and that has the potential to target other viral infections.
OsilodrostatAn oral inhibitor of cortisol synthesis used to treat Cushing's disease by normalizing hypercortisolism.
HydroflumethiazideA thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure and liver cirrhosis.
ArtesunateArtesunate is an artemesinin derivative indicated for the initial treatment of severe malaria.
Drugs & Drug Targets
DrugTargetType
IvosidenibIsocitrate dehydrogenase [NADP] cytoplasmictarget
IvosidenibCytochrome P450 3A4enzyme
IvosidenibCytochrome P450 2B6enzyme
IvosidenibCytochrome P450 2C9enzyme
IvosidenibCytochrome P450 2C8enzyme
IvosidenibSolute carrier family 22 member 8transporter
IvosidenibP-glycoprotein 1transporter
LenvatinibVascular endothelial growth factor receptor 1target
LenvatinibVascular endothelial growth factor receptor 2target
LenvatinibVascular endothelial growth factor receptor 3target
LenvatinibFibroblast growth factor receptor 1target
LenvatinibFibroblast growth factor receptor 2target
LenvatinibFibroblast growth factor receptor 3target
LenvatinibFibroblast growth factor receptor 4target
LenvatinibPlatelet-derived growth factor receptor alphatarget
LenvatinibProto-oncogene tyrosine-protein kinase receptor Rettarget
LenvatinibMast/stem cell growth factor receptor Kittarget
LenvatinibP-glycoprotein 1transporter
LenvatinibATP-binding cassette sub-family G member 2transporter
LenvatinibCytochrome P450 3A4enzyme
LenvatinibAldehyde oxidaseenzyme
LenvatinibCytochrome P450 2C8enzyme
LenvatinibCytochrome P450 2C9enzyme
LenvatinibCytochrome P450 1A2enzyme
LenvatinibCytochrome P450 2B6enzyme
LenvatinibCytochrome P450 2C19enzyme
LenvatinibSolute carrier family 22 member 6transporter
LenvatinibSolute carrier family 22 member 8transporter
LenvatinibSolute carrier family 22 member 2transporter
LenvatinibSolute carrier organic anion transporter family member 1B1transporter
LenvatinibBile salt export pumptransporter
LenvatinibCytochrome P450 2D6enzyme
TeriflunomideATP-binding cassette sub-family G member 2transporter
TeriflunomideDihydroorotate dehydrogenase (quinone), mitochondrialtarget
TeriflunomideCytochrome P450 2C8enzyme
TeriflunomideSolute carrier organic anion transporter family member 1B1transporter
TeriflunomideCytochrome P450 1A2enzyme
ProbenecidSolute carrier family 22 member 8target
ProbenecidSolute carrier family 22 member 11target
ProbenecidSerum albumincarrier
ProbenecidSolute carrier family 22 member 2transporter
ProbenecidSolute carrier family 22 member 1transporter
ProbenecidCanalicular multispecific organic anion transporter 2transporter
ProbenecidMultidrug resistance-associated protein 4transporter
ProbenecidMultidrug resistance-associated protein 5transporter
ProbenecidMonocarboxylate transporter 2transporter
ProbenecidSolute carrier family 22 member 5transporter
ProbenecidMultidrug resistance-associated protein 6transporter
ProbenecidMultidrug resistance-associated protein 1transporter
ProbenecidSolute carrier organic anion transporter family member 1A2transporter
ProbenecidMonocarboxylate transporter 1transporter
ProbenecidSodium/bile acid cotransportertransporter
ProbenecidSolute carrier family 22 member 6transporter
ProbenecidSolute carrier family 22 member 10transporter
ProbenecidSolute carrier family 22 member 8transporter
ProbenecidCanalicular multispecific organic anion transporter 1transporter
ProbenecidATP-binding cassette sub-family C member 11transporter
ProbenecidSolute carrier family 22 member 11transporter
ProbenecidSolute carrier organic anion transporter family member 1C1transporter
ProbenecidSolute carrier family 22 member 7transporter
ProbenecidSolute carrier family 22 member 6target
ProbenecidPannexin-1target
ProbenecidCytochrome P450 2C8enzyme
ProbenecidCytochrome P450 3A4enzyme
ProbenecidSolute carrier family 22 member 12transporter
ProbenecidSolute carrier family 2, facilitated glucose transporter member 9transporter
ProbenecidTaste receptor type 2 member 16target
ProbenecidUDP-glucuronosyltransferase 1-1enzyme
ProbenecidCytochrome P450 2C9enzyme
Taurocholic acidBile salt-activated lipasetarget
Taurocholic acidGastrotropintarget
Taurocholic acidBile salt export pumptransporter
Taurocholic acidMultidrug resistance-associated protein 1transporter
Taurocholic acidSolute carrier organic anion transporter family member 1A2transporter
Taurocholic acidIleal sodium/bile acid cotransportertransporter
Taurocholic acidCanalicular multispecific organic anion transporter 1transporter
Taurocholic acidSolute carrier organic anion transporter family member 1B1transporter
Taurocholic acidCanalicular multispecific organic anion transporter 2transporter
Taurocholic acidMultidrug resistance-associated protein 4transporter
Taurocholic acidP-glycoprotein 1transporter
Taurocholic acidSolute carrier family 22 member 6transporter
Taurocholic acidMultidrug resistance-associated protein 7transporter
Taurocholic acidSolute carrier family 22 member 8transporter
Taurocholic acidSolute carrier organic anion transporter family member 4A1transporter
Taurocholic acidATP-binding cassette sub-family C member 11transporter
Taurocholic acidSolute carrier organic anion transporter family member 1C1transporter
Taurocholic acidSolute carrier organic anion transporter family member 3A1transporter
Taurocholic acidATP-binding cassette sub-family G member 2transporter
Taurocholic acidSolute carrier organic anion transporter family member 2B1transporter
Taurocholic acidMonocarboxylate transporter 1transporter
Taurocholic acidSodium/bile acid cotransportertransporter
Taurocholic acidOrganic solute transporter subunit alphatransporter
Taurocholic acidOrganic solute transporter subunit betatransporter
Taurocholic acidSolute carrier organic anion transporter family member 1B3transporter
Taurocholic acidCystine/glutamate transportertransporter
Taurocholic acidBile acid receptortarget
Salicylic acidSerum albumincarrier
Salicylic acidProstaglandin G/H synthase 1target
Salicylic acidProstaglandin G/H synthase 2target
Salicylic acidAldo-keto reductase family 1 member C1target
Salicylic acidSolute carrier family 22 member 6transporter
Salicylic acidSolute carrier family 22 member 10transporter
Salicylic acidSolute carrier family 22 member 8transporter
Salicylic acidSolute carrier family 22 member 11transporter
Salicylic acidSolute carrier organic anion transporter family member 2B1transporter
Salicylic acidMonocarboxylate transporter 1transporter
Salicylic acidSolute carrier family 22 member 7transporter
Salicylic acidCytochrome P450 2C9enzyme
QuinidineSodium channel protein type 5 subunit alphatarget
QuinidineAlpha-1-acid glycoprotein 1carrier
QuinidinePotassium voltage-gated channel subfamily H member 2target
QuinidinePotassium channel subfamily K member 1target
QuinidinePotassium channel subfamily K member 6target
QuinidineCytochrome P450 1A2enzyme
QuinidineCytochrome P450 2E1enzyme
QuinidineCytochrome P450 1A1enzyme
QuinidineCytochrome P450 2D6enzyme
QuinidineCytochrome P450 3A4enzyme
QuinidineCytochrome P450 3A7enzyme
QuinidineSolute carrier family 22 member 2transporter
QuinidineSolute carrier family 22 member 1transporter
QuinidineSolute carrier family 22 member 5transporter
QuinidineP-glycoprotein 1transporter
QuinidineSolute carrier organic anion transporter family member 1A2transporter
QuinidineSolute carrier family 22 member 8transporter
QuinidineCanalicular multispecific organic anion transporter 1transporter
QuinidineSolute carrier family 22 member 4transporter
QuinidineSolute carrier organic anion transporter family member 1B1transporter
QuinidineCytochrome P450 2B6enzyme
QuinidineCytochrome P450 2C9enzyme
QuinidineAlpha-1A adrenergic receptortarget
QuinidineAlpha-1B adrenergic receptortarget
QuinidineAlpha-1D adrenergic receptortarget
QuinidineBile salt export pumptransporter
QuinidineCytochrome P450 2C8enzyme
BenzylpenicillinSolute carrier family 22 member 5transporter
BenzylpenicillinSolute carrier family 15 member 1transporter
BenzylpenicillinSolute carrier family 15 member 2transporter
BenzylpenicillinSolute carrier family 22 member 6transporter
BenzylpenicillinSolute carrier family 22 member 8transporter
BenzylpenicillinSolute carrier family 22 member 4transporter
BenzylpenicillinSolute carrier family 22 member 11transporter
BenzylpenicillinSolute carrier organic anion transporter family member 2B1transporter
BenzylpenicillinSolute carrier organic anion transporter family member 4A1transporter
BenzylpenicillinSolute carrier organic anion transporter family member 3A1transporter
BenzylpenicillinSolute carrier organic anion transporter family member 1B1transporter
BenzylpenicillinPenicillin-binding protein 3target
BenzylpenicillinSolute carrier family 22 member 8target
BenzylpenicillinSolute carrier family 15 member 1target
BenzylpenicillinSolute carrier family 15 member 2target
BenzylpenicillinBeta-lactamase TEMenzyme
BenzylpenicillinSerum albumincarrier
OuabainSodium/potassium-transporting ATPase subunit alpha-1target
OuabainSolute carrier organic anion transporter family member 1A2transporter
OuabainSolute carrier family 22 member 8transporter
OuabainSolute carrier organic anion transporter family member 4C1transporter
OuabainSolute carrier organic anion transporter family member 1B3transporter
OuabainSolute carrier organic anion transporter family member 1C1transporter
OuabainSolute carrier organic anion transporter family member 1B1transporter
OuabainSodium/potassium-transporting ATPase subunit alpha-2target
OuabainSodium/potassium-transporting ATPase subunit alpha-3target
IndomethacinProstaglandin G/H synthase 1target
IndomethacinProstaglandin G/H synthase 2target
IndomethacinCytochrome P450 2C19enzyme
IndomethacinUDP-glucuronosyltransferase 1-9enzyme
IndomethacinPhospholipase A2, membrane associatedtarget
IndomethacinProstaglandin reductase 2target
IndomethacinLactoylglutathione lyasetarget
IndomethacinProstaglandin D2 receptor 2target
IndomethacinPeroxisome proliferator-activated receptor gammatarget
IndomethacinSerum albumincarrier
IndomethacinCanalicular multispecific organic anion transporter 2transporter
IndomethacinMultidrug resistance-associated protein 4transporter
IndomethacinMultidrug resistance-associated protein 6transporter
IndomethacinP-glycoprotein 1transporter
IndomethacinMultidrug resistance-associated protein 1transporter
IndomethacinSolute carrier organic anion transporter family member 1A2transporter
IndomethacinSolute carrier family 22 member 6transporter
IndomethacinSolute carrier family 22 member 8transporter
IndomethacinCanalicular multispecific organic anion transporter 1transporter
IndomethacinATP-binding cassette sub-family C member 11transporter
IndomethacinSolute carrier family 22 member 11transporter
IndomethacinSodium/bile acid cotransportertransporter
IndomethacinSolute carrier family 22 member 7transporter
IndomethacinCytochrome P450 2C9enzyme
IndomethacinUDP-glucuronosyltransferase 1-1enzyme
IndomethacinLiver carboxylesterase 1enzyme
IndomethacinUDP-glucuronosyltransferase 2B7enzyme
IndomethacinPeroxisome proliferator-activated receptor alphatarget
IndomethacinAldo-keto reductase family 1 member C3target
IndomethacinSolute carrier organic anion transporter family member 1B1transporter
IndomethacinBile salt export pumptransporter
IbuprofenProstaglandin G/H synthase 1target
IbuprofenProstaglandin G/H synthase 2target
IbuprofenCytochrome P450 2C9enzyme
IbuprofenSerum albumincarrier
IbuprofenMultidrug resistance-associated protein 4transporter
IbuprofenMultidrug resistance-associated protein 1transporter
IbuprofenSolute carrier organic anion transporter family member 1A2transporter
IbuprofenSolute carrier family 22 member 6transporter
IbuprofenSolute carrier family 22 member 8transporter
IbuprofenSolute carrier family 22 member 11transporter
IbuprofenSolute carrier organic anion transporter family member 2B1transporter
IbuprofenP-glycoprotein 1transporter
IbuprofenUDP-glucuronosyltransferase 1-3enzyme
IbuprofenUDP-glucuronosyltransferase 1-9enzyme
IbuprofenUDP-glucuronosyltransferase 2B4enzyme
IbuprofenUDP-glucuronosyltransferase 2B7enzyme
IbuprofenCytochrome P450 2C8enzyme
IbuprofenCytochrome P450 2C19enzyme
IbuprofenApoptosis regulator Bcl-2target
IbuprofenThrombomodulintarget
IbuprofenFatty acid-binding protein, intestinaltarget
IbuprofenPeroxisome proliferator-activated receptor gammatarget
IbuprofenCystic fibrosis transmembrane conductance regulatortarget
IbuprofenPeroxisome proliferator-activated receptor alphatarget
IbuprofenPlatelet glycoprotein Ib alpha chaintarget
IbuprofenProtein S100-A7target
IbuprofenAlpha-methylacyl-CoA racemaseenzyme
IbuprofenCytochrome P450 3A4enzyme
GuanidineRibonuclease pancreatictarget
GuanidineDNAtarget
GuanidineDisks large homolog 4target
GuanidineLysozymetarget
GuanidineAldehyde dehydrogenase, mitochondrialtarget
GuanidineGuanidinoacetate N-methyltransferasetarget
GuanidineArginasetarget
GuanidineSolute carrier family 22 member 2transporter
GuanidineSolute carrier family 22 member 1transporter
GuanidineSolute carrier family 22 member 3transporter
GuanidineSolute carrier family 22 member 5transporter
GuanidineSolute carrier family 22 member 8transporter
GuanidineSolute carrier family 22 member 4transporter
GuanidineMultidrug and toxin extrusion protein 1transporter
GuanidineMultidrug and toxin extrusion protein 2transporter
Glutaric AcidAspartate aminotransferasetarget
Glutaric AcidBranched-chain-amino-acid aminotransferasetarget
Glutaric AcidGlutamate decarboxylase alphatarget
Glutaric AcidSolute carrier family 22 member 6transporter
Glutaric AcidSolute carrier family 22 member 8transporter
Glutaric AcidSolute carrier family 22 member 11transporter
Glutaric AcidSolute carrier family 22 member 7transporter
FurosemideSolute carrier family 12 member 1target
FurosemideSerum albumincarrier
FurosemideSolute carrier family 22 member 6transporter
FurosemideSolute carrier family 22 member 5transporter
FurosemideSolute carrier family 22 member 8transporter
FurosemideCanalicular multispecific organic anion transporter 1transporter
FurosemideSolute carrier organic anion transporter family member 2A1transporter
FurosemideSolute carrier family 22 member 11transporter
Furosemide6-phosphogluconate dehydrogenase, decarboxylatingenzyme
FurosemideCarbonic anhydrase 2target
FurosemideUDP-glucuronosyltransferase 1-1enzyme
FurosemideThyroxine-binding globulincarrier
FurosemideG-protein coupled receptor 35target
DiclofenacProstaglandin G/H synthase 1target
DiclofenacProstaglandin G/H synthase 2target
DiclofenacTransthyretincarrier
DiclofenacCytochrome P450 2C9enzyme
DiclofenacCytochrome P450 2C19enzyme
DiclofenacCytochrome P450 1A2enzyme
DiclofenacCytochrome P450 2C8enzyme
DiclofenacSerum albumincarrier
DiclofenacMultidrug resistance-associated protein 4transporter
DiclofenacMultidrug resistance-associated protein 1transporter
DiclofenacSolute carrier family 22 member 6transporter
DiclofenacSolute carrier family 22 member 8transporter
DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DiclofenacSolute carrier family 22 member 11transporter
DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DiclofenacCytochrome P450 3A4enzyme
DiclofenacCytochrome P450 2B6enzyme
DiclofenacCytochrome P450 2C18enzyme
DiclofenacCytochrome P450 2E1enzyme
DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DiclofenacBile salt export pumptransporter
DiclofenacUDP-glucuronosyltransferase 1-3enzyme
DiclofenacUDP-glucuronosyltransferase 1-9enzyme
DiclofenacUDP-glucuronosyltransferase 2B4enzyme
DiclofenacArachidonate 5-lipoxygenaseenzyme
DiclofenacSodium channel protein type 4 subunit alphatransporter
DiclofenacAcid-sensing ion channel 1transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 2transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 3transporter
DiclofenacPhospholipase A2, membrane associatedenzyme
DiclofenacP-glycoprotein 1transporter
Cholic AcidFerrochelatase, mitochondrialtarget
Cholic AcidBile salt export pumptransporter
Cholic AcidP-glycoprotein 1transporter
Cholic AcidMultidrug resistance-associated protein 1transporter
Cholic AcidSolute carrier organic anion transporter family member 1A2transporter
Cholic AcidIleal sodium/bile acid cotransportertransporter
Cholic AcidCanalicular multispecific organic anion transporter 1transporter
Cholic AcidSolute carrier organic anion transporter family member 1B1transporter
Cholic AcidCanalicular multispecific organic anion transporter 2transporter
Cholic AcidMultidrug resistance-associated protein 4transporter
Cholic AcidSodium/bile acid cotransportertransporter
Cholic AcidSolute carrier family 22 member 8transporter
Cholic AcidSolute carrier family 22 member 7transporter
Cholic AcidSolute carrier organic anion transporter family member 1B3transporter
Cholic AcidAlcohol dehydrogenase 1Ctarget
Cholic AcidEstrogen-related receptor gammatarget
Cholic AcidGastrotropintarget
Cholic AcidCytochrome c oxidase subunit 4 isoform 1, mitochondrialtarget
Cholic AcidCytochrome c oxidase subunit 1target
Cholic AcidCytochrome c oxidase subunit 2target
Cholic AcidCytochrome c oxidase subunit 3target
Cholic AcidCytochrome c oxidase subunit 5A, mitochondrialtarget
Cholic AcidCytochrome c oxidase subunit 5B, mitochondrialtarget
Cholic AcidCytochrome c oxidase subunit 6Ctarget
Cholic AcidCytochrome c oxidase subunit 7B, mitochondrialtarget
Cholic AcidCytochrome c oxidase subunit 7C, mitochondrialtarget
Cholic AcidCytochrome c oxidase subunit 8A, mitochondrialtarget
Cholic AcidCytochrome c oxidase subunit 6A2, mitochondrialtarget
Cholic AcidCytochrome c oxidase subunit 6B1target
Cholic AcidCytochrome c oxidase subunit 7A1, mitochondrialtarget
Cholic AcidPhospholipase A2target
Cholic AcidLiver carboxylesterase 1target
Cholic AcidFatty acid-binding protein, livercarrier
Cholic AcidFerrochelatasetarget
Cholic AcidCholoylglycine hydrolasetarget
Cholic AcidBile acid receptortarget
Cholic AcidG-protein coupled bile acid receptor 1target
BumetanideSolute carrier family 12 member 1target
BumetanideCystic fibrosis transmembrane conductance regulatortarget
BumetanideSolute carrier family 12 member 2target
BumetanideSolute carrier family 12 member 4target
BumetanideSolute carrier family 12 member 5target
BumetanideSodium/bile acid cotransportertransporter
BumetanideSolute carrier family 22 member 6transporter
BumetanideSolute carrier family 22 member 8transporter
BumetanideSolute carrier family 22 member 11transporter
BumetanideSolute carrier family 22 member 7transporter
BumetanideSolute carrier organic anion transporter family member 1A2transporter
BumetanideProstaglandin G/H synthase 2enzyme
CilastatinDipeptidase 1target
CilastatinSolute carrier family 22 member 6transporter
CilastatinSolute carrier family 22 member 8transporter
PiroxicamProstaglandin G/H synthase 1target
PiroxicamProstaglandin G/H synthase 2target
PiroxicamSerum albumincarrier
PiroxicamCytochrome P450 2C9enzyme
PiroxicamSolute carrier family 22 member 6transporter
PiroxicamSolute carrier family 22 member 8transporter
PiroxicamSolute carrier family 22 member 11transporter
PiroxicamCytochrome P450 2C8enzyme
PiroxicamSolute carrier organic anion transporter family member 2B1transporter
Aminohippuric acidSolute carrier family 22 member 2transporter
Aminohippuric acidSolute carrier family 22 member 5transporter
Aminohippuric acidSolute carrier family 22 member 6transporter
Aminohippuric acidSolute carrier family 22 member 8transporter
Aminohippuric acidCanalicular multispecific organic anion transporter 1transporter
Aminohippuric acidSolute carrier family 22 member 4transporter
Aminohippuric acidSolute carrier family 22 member 11transporter
Aminohippuric acidSolute carrier organic anion transporter family member 3A1transporter
Aminohippuric acidSolute carrier organic anion transporter family member 1B1transporter
Aminohippuric acidMultidrug resistance-associated protein 1transporter
Aminohippuric acidSolute carrier organic anion transporter family member 1A2transporter
Aminohippuric acidMonocarboxylate transporter 1transporter
Aminohippuric acidSolute carrier family 22 member 7transporter
Caprylic acid3-oxoacyl-[acyl-carrier-protein] synthase 1target
Caprylic acidAcyl-CoA thioesterase Itarget
Caprylic acidSolute carrier family 22 member 6transporter
Caprylic acidSolute carrier family 22 member 8transporter
Caprylic acidSolute carrier family 22 member 11transporter
Caprylic acidPeroxisome proliferator-activated receptor alphatarget
CimetidineHistamine H2 receptortarget
CimetidineCytochrome P450 1A2enzyme
CimetidineCytochrome P450 2D6enzyme
CimetidineCytochrome P450 2C19enzyme
CimetidineCytochrome P450 3A4enzyme
CimetidineCytochrome P450 3A5enzyme
CimetidineP-glycoprotein 1transporter
CimetidineSolute carrier family 22 member 2transporter
CimetidineSolute carrier family 22 member 1transporter
CimetidineSolute carrier family 22 member 3transporter
CimetidineSolute carrier family 22 member 5transporter
CimetidineSolute carrier family 22 member 6transporter
CimetidineSolute carrier family 22 member 8transporter
CimetidineMultidrug and toxin extrusion protein 1transporter
CimetidineSolute carrier family 22 member 4transporter
CimetidineSolute carrier family 22 member 11transporter
CimetidineSolute carrier family 22 member 7transporter
CimetidineCytochrome P450 11B1, mitochondrialenzyme
CimetidineCytochrome P450 2C8enzyme
CimetidineCytochrome P450 2C9enzyme
CimetidineCytochrome P450 2E1enzyme
CimetidineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
CimetidineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
CimetidineBile salt export pumptransporter
CimetidineMultidrug and toxin extrusion protein 2transporter
AspartameTaste receptor type 1 member 2target
AspartameTransient receptor potential cation channel subfamily V member 1target
AspartameSolute carrier family 22 member 6transporter
AspartameSolute carrier family 22 member 8transporter
AspartameSolute carrier family 22 member 11transporter
AspartameTaste receptor type 1 member 3target
Tetracycline16S ribosomal RNAtarget
TetracyclineMajor prion proteintarget
TetracyclineSerum albumincarrier
TetracyclineCytochrome P450 3A4enzyme
TetracyclineSolute carrier family 22 member 6transporter
TetracyclineSolute carrier family 22 member 8transporter
TetracyclineSolute carrier family 22 member 11transporter
TetracyclineSolute carrier family 22 member 7transporter
Tetracycline30S ribosomal protein S3target
Tetracycline30S ribosomal protein S8target
Tetracycline30S ribosomal protein S19target
Tetracycline30S ribosomal protein S14target
Tetracycline30S ribosomal protein S7target
TetracyclineMultidrug translocase MdfAtarget
TetracyclineProtein-arginine deiminase type-4target
TetracyclineSolute carrier organic anion transporter family member 2B1transporter
Oxytetracycline30S ribosomal protein S4target
Oxytetracycline30S ribosomal protein S9target
Oxytetracycline16S ribosomal RNAtarget
OxytetracyclineSolute carrier family 22 member 6transporter
OxytetracyclineSolute carrier family 22 member 8transporter
OxytetracyclineSolute carrier family 22 member 11transporter
OxytetracyclineSolute carrier family 22 member 7transporter
OxytetracyclineSerum albumincarrier
Minocycline30S ribosomal protein S4target
Minocycline30S ribosomal protein S9target
Minocycline16S ribosomal RNAtarget
MinocyclineInterleukin-1 betatarget
MinocyclineArachidonate 5-lipoxygenasetarget
MinocyclineMatrix metalloproteinase-9target
MinocyclineVascular endothelial growth factor Atarget
MinocyclineCaspase-1target
MinocyclineCaspase-3target
MinocyclineCytochrome ctarget
MinocyclineSolute carrier family 22 member 6transporter
MinocyclineSolute carrier family 22 member 7transporter
MinocyclineOuter membrane protein Ftransporter
MinocyclineOuter membrane porin Ctransporter
MinocyclineMitogen-activated Protein Kinasestarget
MinocyclineNitric oxide synthase, inducibletarget
GanciclovirDNA polymerase catalytic subunittarget
GanciclovirThymidine kinasetarget
GanciclovirSolute carrier family 22 member 1transporter
GanciclovirSolute carrier family 22 member 6transporter
GanciclovirSolute carrier family 22 member 8transporter
GanciclovirSolute carrier family 22 member 7transporter
GanciclovirDNAtarget
GanciclovirMultidrug and toxin extrusion protein 1transporter
GanciclovirMultidrug and toxin extrusion protein 2transporter
AcyclovirDNA polymerase catalytic subunittarget
AcyclovirDNA polymerase catalytic subunittarget
AcyclovirThymidine kinasetarget
AcyclovirSolute carrier family 22 member 1transporter
AcyclovirSolute carrier family 22 member 6transporter
AcyclovirSolute carrier family 22 member 8transporter
AcyclovirIleal sodium/bile acid cotransportertransporter
AcyclovirMultidrug and toxin extrusion protein 1transporter
AcyclovirMultidrug and toxin extrusion protein 2transporter
AcyclovirThymidine kinaseenzyme
AcyclovirGuanylate kinaseenzyme
AcyclovirNucleoside diphosphokinaseenzyme
AcyclovirPyruvate Kinasesenzyme
AcyclovirCreatine Kinasesenzyme
AcyclovirPhosphoglycerate Kinasesenzyme
AcyclovirSuccinyl-CoA Synthetasesenzyme
AcyclovirPhosphoenolpyruvate Carboxykinasesenzyme
AcyclovirAdenylosuccinate Synthetasesenzyme
AcyclovirSerum albumincarrier
DinoprostoneProstaglandin E2 receptor EP2 subtypetarget
DinoprostoneProstaglandin E2 receptor EP1 subtypetarget
DinoprostoneProstaglandin E2 receptor EP4 subtypetarget
DinoprostoneProstaglandin E2 receptor EP3 subtypetarget
DinoprostoneSolute carrier family 22 member 2transporter
DinoprostoneMultidrug resistance-associated protein 5transporter
DinoprostoneSolute carrier family 22 member 6transporter
DinoprostoneSolute carrier family 22 member 8transporter
DinoprostoneSolute carrier family 22 member 11transporter
DinoprostoneSolute carrier family 22 member 7transporter
DinoprostoneMultidrug resistance-associated protein 4transporter
DinoprostoneSolute carrier organic anion transporter family member 2B1transporter
DinoprostoneSolute carrier organic anion transporter family member 1A2transporter
DinoprostoneOrganic solute transporter subunit alphatransporter
DinoprostoneOrganic solute transporter subunit betatransporter
DinoprostoneSolute carrier organic anion transporter family member 2A1transporter
DinoprostoneSolute carrier organic anion transporter family member 4A1transporter
DinoprostoneSolute carrier organic anion transporter family member 1C1transporter
DinoprostoneSolute carrier organic anion transporter family member 3A1transporter
DinoprostoneSolute carrier organic anion transporter family member 1B1transporter
DinoprostoneProstaglandin D2 receptor 2target
CefalotinPenicillin-binding protein 1Atarget
CefalotinD-alanyl-D-alanine carboxypeptidasetarget
CefalotinBeta-lactamasetarget
CefalotinSolute carrier family 22 member 5transporter
CefalotinSolute carrier family 15 member 1transporter
CefalotinSolute carrier family 15 member 2transporter
CefalotinSolute carrier family 22 member 6transporter
CefalotinSolute carrier family 22 member 8transporter
CefalotinSolute carrier family 22 member 11transporter
CefalotinSolute carrier family 22 member 7transporter
CefalotinPenicillin-binding protein 1Atarget
CefalotinPenicillin-binding protein 1btarget
CefalotinPenicillin-binding protein 3target
CefalotinPenicillin-binding protein 2atarget
CefalotinPenicillin-binding protein 2Btarget
CefalotinSerum albumincarrier
CefoperazoneSerum albumincarrier
CefoperazoneSolute carrier family 22 member 6transporter
CefoperazoneSolute carrier family 22 member 8transporter
CefoperazoneSolute carrier family 22 member 11transporter
CefoperazoneSolute carrier family 22 member 7transporter
CefoperazonePeptidoglycan synthase FtsItarget
CefoperazonePenicillin-binding protein 1Btarget
CefoperazonePenicillin-binding protein 2target
CefoperazonePenicillin-binding protein 1Atarget
CefoperazoneD-alanyl-D-alanine carboxypeptidase DacCtarget
CefoperazoneD-alanyl-D-alanine carboxypeptidase DacAtarget
CefoperazoneD-alanyl-D-alanine carboxypeptidase DacBtarget
CefoperazonePenicillin-binding protein 1Atarget
CefoperazonePenicillin-binding protein 1Btarget
CefazolinSerum paraoxonase/arylesterase 1target
CefazolinSerum albumincarrier
CefazolinSolute carrier family 22 member 6transporter
CefazolinSolute carrier family 22 member 8transporter
CefazolinSolute carrier family 22 member 11transporter
CefazolinPenicillin-binding protein 1Atarget
CefazolinPenicillin-binding protein 1Btarget
CefazolinPenicillin-binding protein 2target
CefazolinPenicillin-binding protein 1Ctarget
CefazolinPeptidoglycan synthase FtsItarget
CefazolinMultidrug resistance-associated protein 4transporter
CefazolinThiopurine S-methyltransferaseenzyme
CefazolinInterleukin-15target
CefazolinInterleukin-2target
CefamandoleSolute carrier family 22 member 6transporter
CefamandoleSolute carrier family 22 member 8transporter
CefamandoleSolute carrier family 22 member 11transporter
CefamandoleSolute carrier family 22 member 7transporter
CefamandolePenicillin-binding protein 2target
CefadroxilSolute carrier family 22 member 5transporter
CefadroxilSolute carrier family 15 member 1transporter
CefadroxilSolute carrier family 15 member 2transporter
CefadroxilSolute carrier family 22 member 6transporter
CefadroxilSolute carrier family 22 member 8transporter
CefadroxilPenicillin-binding protein 3target
CefadroxilPenicillin-binding protein 1Atarget
CefadroxilPenicillin-binding protein 1btarget
CefadroxilPenicillin-binding protein 2Btarget
CeftriaxoneSerum albumincarrier
CeftriaxoneSolute carrier family 15 member 1transporter
CeftriaxoneSolute carrier family 15 member 2transporter
CeftriaxoneSolute carrier family 22 member 6transporter
CeftriaxoneSolute carrier family 22 member 8transporter
CeftriaxoneSolute carrier family 22 member 11transporter
CeftriaxonePenicillin-binding protein 2Btarget
CeftriaxoneGlutamine synthetaseenzyme
CeftriaxoneSolute carrier family 22 member 11target
CeftriaxoneSolute carrier family 22 member 6target
CeftriaxoneSolute carrier family 22 member 8target
CeftriaxoneSolute carrier family 15 member 1target
CeftriaxoneP-glycoprotein 1transporter
CefotaximePenicillin-binding protein 3target
CefotaximeSolute carrier family 15 member 1transporter
CefotaximeSolute carrier family 15 member 2transporter
CefotaximeSolute carrier family 22 member 6transporter
CefotaximeSolute carrier family 22 member 8transporter
CefotaximeSolute carrier family 22 member 11transporter
CefotaximeSolute carrier family 22 member 7transporter
CefotaximePenicillin-binding protein 1btarget
CefotaximePenicillin-binding protein 2atarget
CefotaximePenicillin-binding protein 1Atarget
CefotaximePenicillin-binding protein 2Btarget
CefotaximeSolute carrier family 22 member 6target
CefotaximeSolute carrier family 22 member 8target
CefotaximeSolute carrier family 22 member 11target
CefotaximeSolute carrier family 22 member 7target
CefotaximeSolute carrier family 15 member 1target
CefotaximeSerum albumintarget
CefotaximeBeta-lactamasetarget
CefotaximeSolute carrier family 15 member 2target
PhenylbutazoneProstaglandin G/H synthase 2target
PhenylbutazoneProstacyclin synthasetarget
PhenylbutazoneCytochrome P450 2C9enzyme
PhenylbutazoneSolute carrier family 22 member 6transporter
PhenylbutazoneSolute carrier family 22 member 8transporter
PhenylbutazoneSolute carrier family 22 member 11transporter
PhenylbutazoneProstaglandin G/H synthase 1target
PhenylbutazoneCytochrome P450 3A4enzyme
KetoprofenProstaglandin G/H synthase 1target
KetoprofenProstaglandin G/H synthase 2target
KetoprofenC-X-C chemokine receptor type 1target
KetoprofenSerum albumincarrier
KetoprofenMultidrug resistance-associated protein 4transporter
KetoprofenSolute carrier organic anion transporter family member 1A2transporter
KetoprofenSolute carrier family 22 member 6transporter
KetoprofenSolute carrier family 22 member 8transporter
KetoprofenSolute carrier family 22 member 11transporter
KetoprofenSolute carrier family 22 member 7transporter
KetoprofenCytochrome P450 2C9enzyme
KetoprofenCytochrome P450 2C8enzyme
KetoprofenUDP-glucuronosyltransferase 1-1enzyme
FamotidineHistamine H2 receptortarget
FamotidineSolute carrier family 22 member 2transporter
FamotidineSolute carrier family 22 member 8transporter
FamotidineMultidrug and toxin extrusion protein 1transporter
FamotidineCytochrome P450 1A2enzyme
FamotidineSolute carrier family 22 member 6transporter
LiothyronineThyroid hormone receptor betatarget
LiothyronineThyroid hormone receptor alphatarget
LiothyronineThyroxine-binding globulincarrier
LiothyronineTransthyretincarrier
LiothyronineSerum albumincarrier
LiothyronineP-glycoprotein 1transporter
LiothyronineSolute carrier family 22 member 8transporter
LiothyronineMonocarboxylate transporter 10transporter
LiothyronineSolute carrier organic anion transporter family member 4A1transporter
LiothyronineSolute carrier organic anion transporter family member 1C1transporter
LiothyronineSolute carrier organic anion transporter family member 1A2transporter
LiothyronineSodium/bile acid cotransportertransporter
LiothyronineSolute carrier organic anion transporter family member 4C1transporter
LiothyronineSolute carrier organic anion transporter family member 1B3transporter
LiothyronineSolute carrier organic anion transporter family member 1B1transporter
LiothyronineLarge neutral amino acids transporter small subunit 1transporter
LiothyronineProliferating cell nuclear antigentarget
LiothyronineUDP-glucuronosyltransferase 1-1enzyme
MethotrexateDihydrofolate reductasetarget
MethotrexateAldehyde oxidaseenzyme
MethotrexateMethylenetetrahydrofolate reductaseenzyme
MethotrexateSerum albumincarrier
MethotrexateCanalicular multispecific organic anion transporter 2transporter
MethotrexateMultidrug resistance-associated protein 4transporter
MethotrexateMultidrug resistance-associated protein 1transporter
MethotrexateSolute carrier family 22 member 6transporter
MethotrexateMultidrug resistance-associated protein 7transporter
MethotrexateSolute carrier family 22 member 8transporter
MethotrexateCanalicular multispecific organic anion transporter 1transporter
MethotrexateP-glycoprotein 1transporter
MethotrexateSolute carrier organic anion transporter family member 1A2transporter
MethotrexateMonocarboxylate transporter 1transporter
MethotrexateATP-binding cassette sub-family C member 11transporter
MethotrexateSolute carrier organic anion transporter family member 1B3transporter
MethotrexateSolute carrier family 22 member 11transporter
MethotrexateSolute carrier organic anion transporter family member 1C1transporter
MethotrexateSolute carrier organic anion transporter family member 3A1transporter
MethotrexateATP-binding cassette sub-family G member 2transporter
MethotrexateSolute carrier family 22 member 7transporter
MethotrexateSolute carrier organic anion transporter family member 1B1transporter
Methotrexate6-phosphogluconate dehydrogenase, decarboxylatingenzyme
MethotrexateProton-coupled folate transportertransporter
MethotrexateFolylpolyglutamate synthase, mitochondrialenzyme
MethotrexateGamma-glutamyl hydrolaseenzyme
MethotrexateDihydrofolate reductaseenzyme
MethotrexateThymidylate synthaseenzyme
MethotrexateBifunctional purine biosynthesis protein PURHenzyme
MethotrexateSolute carrier organic anion transporter family member 4C1transporter
MethotrexateFolate transporter 1transporter
MethotrexateFolate receptor alphatransporter
MethotrexateCytochrome P450 3A4enzyme
MethotrexateThymidylate synthasetarget
MethotrexateBifunctional purine biosynthesis protein PURHtarget
MethotrexateFolate receptor betatransporter
MethotrexateSolute carrier family 15 member 1transporter
MethotrexateProton-coupled amino acid transporter 1transporter
Conjugated estrogensEstrogen receptor alphatarget
Conjugated estrogensCytochrome P450 3A4enzyme
Conjugated estrogensCytochrome P450 1A2enzyme
Conjugated estrogensCatechol O-methyltransferaseenzyme
Conjugated estrogensCanalicular multispecific organic anion transporter 2transporter
Conjugated estrogensMultidrug resistance-associated protein 4transporter
Conjugated estrogensMultidrug resistance-associated protein 1transporter
Conjugated estrogensSolute carrier organic anion transporter family member 1A2transporter
Conjugated estrogensSodium/bile acid cotransportertransporter
Conjugated estrogensSolute carrier family 22 member 10transporter
Conjugated estrogensSolute carrier family 22 member 8transporter
Conjugated estrogensSolute carrier organic anion transporter family member 1C1transporter
Conjugated estrogensSolute carrier organic anion transporter family member 1B1transporter
Conjugated estrogensSolute carrier organic anion transporter family member 2B1transporter
Conjugated estrogensP-glycoprotein 1transporter
Conjugated estrogensSolute carrier family 22 member 6transporter
Conjugated estrogensOrganic solute transporter subunit alphatransporter
Conjugated estrogensOrganic solute transporter subunit betatransporter
Conjugated estrogensCanalicular multispecific organic anion transporter 1transporter
Conjugated estrogensSolute carrier organic anion transporter family member 4A1transporter
Conjugated estrogensATP-binding cassette sub-family C member 11transporter
Conjugated estrogensSolute carrier organic anion transporter family member 1B3transporter
Conjugated estrogensSolute carrier family 22 member 11transporter
Conjugated estrogensSolute carrier organic anion transporter family member 3A1transporter
Conjugated estrogensATP-binding cassette sub-family G member 2transporter
Conjugated estrogensThyroxine-binding globulincarrier
Conjugated estrogensSex hormone-binding globulincarrier
Conjugated estrogensSerum albumincarrier
Conjugated estrogensEstrogen receptor betatarget
TenoxicamProstaglandin G/H synthase 1target
TenoxicamProstaglandin G/H synthase 2target
TenoxicamCytochrome P450 2C9enzyme
TenoxicamSolute carrier family 22 member 8transporter
EnalaprilAngiotensin-converting enzymetarget
EnalaprilP-glycoprotein 1transporter
EnalaprilSolute carrier family 15 member 1transporter
EnalaprilSolute carrier family 22 member 6transporter
EnalaprilSolute carrier family 22 member 8transporter
EnalaprilSolute carrier family 22 member 7transporter
EnalaprilSolute carrier organic anion transporter family member 1A2transporter
EnalaprilSerum albumincarrier
trans-2-hydroxycinnamic acidMajor NAD(P)H-flavin oxidoreductasetarget
trans-2-hydroxycinnamic acidSolute carrier family 22 member 8transporter
CephalexinSerum albumincarrier
CephalexinSolute carrier family 22 member 5transporter
CephalexinSolute carrier family 15 member 1transporter
CephalexinSolute carrier family 15 member 2transporter
CephalexinSolute carrier family 22 member 6transporter
CephalexinSolute carrier family 22 member 8transporter
CephalexinMultidrug and toxin extrusion protein 1transporter
CephalexinPenicillin-binding protein 3target
CephalexinPenicillin-binding protein 2atarget
CephalexinPenicillin-binding protein 1btarget
CephalexinPenicillin-binding protein 1Atarget
CephalexinPenicillin-binding protein 2Btarget
Valproic acidHistone deacetylase 9target
Valproic acidShort/branched chain specific acyl-CoA dehydrogenase, mitochondrialtarget
Valproic acidCytochrome P450 2A6enzyme
Valproic acidCytochrome P450 2B6enzyme
Valproic acidCytochrome P450 2C9enzyme
Valproic acidSolute carrier family 22 member 5transporter
Valproic acidSolute carrier family 22 member 6transporter
Valproic acidSolute carrier family 22 member 8transporter
Valproic acidMonocarboxylate transporter 1transporter
Valproic acidSolute carrier family 22 member 7transporter
Valproic acidCytochrome P450 3A5enzyme
Valproic acidUDP-glucuronosyltransferase 1-9enzyme
Valproic acidProstaglandin G/H synthase 1enzyme
Valproic acidCytochrome P450 1A2enzyme
Valproic acidCytochrome P450 2C19enzyme
Valproic acidCytochrome P450 3A4enzyme
Valproic acidUDP-glucuronosyltransferase 1-4enzyme
Valproic acidUDP-glucuronosyltransferase 1-8enzyme
Valproic acidUDP-glucuronosyltransferase 1-10enzyme
Valproic acidUDP-glucuronosyltransferase 1-6enzyme
Valproic acidUDP-glucuronosyltransferase 1-3enzyme
Valproic acidUDP-glucuronosyltransferase 2B7enzyme
Valproic acidUDP-glucuronosyltransferase 2B15enzyme
Valproic acid2-oxoglutarate dehydrogenase, mitochondrialtarget
Valproic acidSuccinate-semialdehyde dehydrogenase, mitochondrialtarget
Valproic acidSodium channel proteintarget
Valproic acidHistone deacetylase 2target
Valproic acidPeroxisome proliferator-activated receptor alphatarget
Valproic acidPeroxisome proliferator-activated receptor deltatarget
Valproic acidPeroxisome proliferator-activated receptor gammatarget
Valproic acidSerum albumincarrier
Valproic acidUDP-glucuronosyltransferase 1-1enzyme
Valproic acidSolute carrier organic anion transporter family member 2B1transporter
MelatoninAcetylserotonin O-methyltransferasetarget
MelatoninMelatonin receptor type 1Atarget
MelatoninMelatonin receptor type 1Btarget
MelatoninNuclear receptor ROR-betatarget
MelatoninCalmodulintarget
MelatoninCalreticulintarget
MelatoninRibosyldihydronicotinamide dehydrogenase [quinone]target
MelatoninMyeloperoxidasetarget
MelatoninEstrogen receptor alphatarget
MelatoninEosinophil peroxidasetarget
MelatoninCytochrome P450 1A1enzyme
MelatoninCytochrome P450 1A2enzyme
MelatoninCytochrome P450 2C19enzyme
MelatoninCytochrome P450 2C9enzyme
MelatoninAcetylserotonin O-methyltransferaseenzyme
MelatoninIndoleamine 2,3-dioxygenase 1enzyme
MelatoninMyeloperoxidaseenzyme
MelatoninCytochrome P450 1B1enzyme
MelatoninSolute carrier family 22 member 8transporter
MelatoninCytochrome P450 19A1enzyme
Benzoic acidCocaine esterasetarget
Benzoic acidD-amino-acid oxidasetarget
Benzoic acidChlorocatechol 1,2-dioxygenasetarget
Benzoic acid2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolasetarget
Benzoic acidNon-heme chloroperoxidasetarget
Benzoic acidOxygen-insensitive NAD(P)H nitroreductasetarget
Benzoic acidHydroxyquinol 1,2-dioxygenasetarget
Benzoic acidReplication proteintarget
Benzoic acidSolute carrier organic anion transporter family member 2B1transporter
Benzoic acidSolute carrier family 22 member 8transporter
Benzoic acidMonocarboxylate transporter 1transporter
Benzoic acidSolute carrier family 15 member 1target
MercaptopurineThiopurine S-methyltransferaseenzyme
MercaptopurineXanthine dehydrogenase/oxidaseenzyme
MercaptopurineHypoxanthine-guanine phosphoribosyltransferasetarget
MercaptopurineSolute carrier family 22 member 8transporter
MercaptopurineMultidrug resistance-associated protein 4transporter
MercaptopurineMultidrug resistance-associated protein 5transporter
MercaptopurineSodium/nucleoside cotransporter 2transporter
MercaptopurineSolute carrier family 28 member 3transporter
MercaptopurineEquilibrative nucleoside transporter 1transporter
MercaptopurineEquilibrative nucleoside transporter 2transporter
MercaptopurineAldehyde oxidaseenzyme
MercaptopurineAmidophosphoribosyltransferasetarget
MercaptopurineInosine-5'-monophosphate dehydrogenasetarget
NovobiocinDNA gyrase subunit Btarget
NovobiocinSolute carrier family 22 member 6transporter
NovobiocinSolute carrier family 22 member 8transporter
NovobiocinSolute carrier family 22 member 11transporter
NovobiocinATP-binding cassette sub-family G member 2transporter
NovobiocinDNA topoisomerase 1target
NovobiocinSolute carrier organic anion transporter family member 1B1transporter
NovobiocinSolute carrier organic anion transporter family member 1B3transporter
NovobiocinSolute carrier organic anion transporter family member 2B1transporter
LiotrixThyroid hormone receptor alphatarget
LiotrixThyroid hormone receptor betatarget
LiotrixCytochrome P450 2C8enzyme
LiotrixSolute carrier organic anion transporter family member 1A2transporter
LiotrixSolute carrier organic anion transporter family member 1B1transporter
LiotrixSolute carrier organic anion transporter family member 1B3transporter
LiotrixSolute carrier organic anion transporter family member 4C1transporter
LiotrixSodium/bile acid cotransportertransporter
LiotrixSolute carrier organic anion transporter family member 1C1transporter
LiotrixSolute carrier organic anion transporter family member 4A1transporter
LiotrixSolute carrier family 22 member 8transporter
LiotrixMonocarboxylate transporter 8transporter
LiotrixMonocarboxylate transporter 10transporter
LiotrixP-glycoprotein 1transporter
LiotrixTransthyretincarrier
LiotrixThyroxine-binding globulincarrier
LiotrixSerum albumincarrier
LiotrixCytochrome P450 3A4enzyme
CefacetrilePenicillin-binding protein 1Atarget
CefacetrilePenicillin-binding protein 1Btarget
CefacetrileSolute carrier family 22 member 6transporter
CefacetrileSolute carrier family 22 member 8transporter
ZidovudineSerum albumincarrier
ZidovudineCytochrome P450 2A6enzyme
ZidovudineCytochrome P450 2C9enzyme
ZidovudineCytochrome P450 3A4enzyme
ZidovudineReverse transcriptase/RNaseHtarget
ZidovudineSolute carrier family 22 member 2transporter
ZidovudineSolute carrier family 22 member 6transporter
ZidovudineSolute carrier family 22 member 7transporter
ZidovudineSolute carrier family 22 member 8transporter
ZidovudineSolute carrier family 22 member 11transporter
ZidovudineSodium/nucleoside cotransporter 1transporter
ZidovudineEquilibrative nucleoside transporter 2transporter
ZidovudineP-glycoprotein 1transporter
ZidovudineMultidrug resistance-associated protein 4transporter
ZidovudineMultidrug resistance-associated protein 5transporter
ZidovudineATP-binding cassette sub-family G member 2transporter
ZidovudineTelomerase reverse transcriptasetarget
ZidovudineThymidine kinase, cytosolicenzyme
ZidovudineUDP-glucuronosyltransferase 2B7enzyme
ZidovudineUDP-glucuronosyltransferase 1-1enzyme
DabrafenibCytochrome P450 3A4enzyme
DabrafenibCytochrome P450 2C8enzyme
DabrafenibP-glycoprotein 1transporter
DabrafenibATP-binding cassette sub-family G member 2transporter
DabrafenibSolute carrier organic anion transporter family member 1B1transporter
DabrafenibSolute carrier organic anion transporter family member 1B3transporter
DabrafenibSolute carrier family 22 member 6transporter
DabrafenibSolute carrier family 22 member 8transporter
DabrafenibSerine/threonine-protein kinase B-raftarget
DabrafenibRAF proto-oncogene serine/threonine-protein kinasetarget
DabrafenibSerine/threonine-protein kinase SIK1target
DabrafenibSerine/threonine-protein kinase Nek11target
DabrafenibLIM domain kinase 1target
DabrafenibCytochrome P450 2B6enzyme
DabrafenibCytochrome P450 2C9enzyme
TopiroxostatXanthine dehydrogenase/oxidasetarget
TopiroxostatATP-binding cassette sub-family G member 2transporter
TopiroxostatSerum albumincarrier
TopiroxostatAlpha-1-acid glycoprotein 1carrier
TopiroxostatCytochrome P450 2C8enzyme
TopiroxostatCytochrome P450 2C9enzyme
TopiroxostatCytochrome P450 1A1enzyme
TopiroxostatCytochrome P450 3A4enzyme
TopiroxostatCytochrome P450 2C19enzyme
TopiroxostatSolute carrier family 22 member 8transporter
TopiroxostatSolute carrier family 22 member 6transporter
TopiroxostatUDP-glucuronosyltransferase 1-9enzyme
AtalurenUDP-glucuronosyltransferase 1-9enzyme
AtalurenSolute carrier family 22 member 6enzyme
AtalurenSolute carrier family 22 member 8enzyme
AtalurenSolute carrier organic anion transporter family member 1B3enzyme
EnasidenibCytochrome P450 1A2enzyme
EnasidenibCytochrome P450 2B6enzyme
EnasidenibIsocitrate dehydrogenase [NADP], mitochondrialtarget
EnasidenibCytochrome P450 2C8enzyme
EnasidenibCytochrome P450 2C9enzyme
EnasidenibCytochrome P450 2C19enzyme
EnasidenibCytochrome P450 2D6enzyme
EnasidenibCytochrome P450 3A4enzyme
EnasidenibUDP-glucuronosyltransferase 1-1enzyme
EnasidenibUDP-glucuronosyltransferase 1-3enzyme
EnasidenibUDP-glucuronosyltransferase 1-4enzyme
EnasidenibUDP-glucuronosyltransferase 1-9enzyme
EnasidenibUDP-glucuronosyltransferase 2B7enzyme
EnasidenibUDP-glucuronosyltransferase 2B15enzyme
EnasidenibP-glycoprotein 1transporter
EnasidenibATP-binding cassette sub-family G member 2transporter
EnasidenibSolute carrier family 22 member 6transporter
EnasidenibSolute carrier organic anion transporter family member 1B1transporter
EnasidenibSolute carrier family 22 member 2transporter
EnasidenibSolute carrier organic anion transporter family member 1B3transporter
EnasidenibSolute carrier family 22 member 8transporter
LetermovirUDP-glucuronosyltransferase 1-1enzyme
LetermovirUDP-glucuronosyltransferase 1-3enzyme
LetermovirSolute carrier organic anion transporter family member 1B1transporter
LetermovirSolute carrier organic anion transporter family member 1B3transporter
LetermovirTripartite terminase subunit 1target
LetermovirTripartite terminase subunit 2target
LetermovirTripartite terminase subunit 3target
LetermovirCytochrome P450 2D6enzyme
LetermovirCytochrome P450 2C8enzyme
LetermovirCytochrome P450 2C19enzyme
LetermovirCytochrome P450 2C9enzyme
LetermovirCytochrome P450 2B6enzyme
LetermovirP-glycoprotein 1transporter
LetermovirATP-binding cassette sub-family G member 2transporter
LetermovirBile salt export pumptransporter
LetermovirSolute carrier family 22 member 8transporter
LetermovirCanalicular multispecific organic anion transporter 1transporter
LetermovirCytochrome P450 3A4enzyme
LetermovirCytochrome P450 3A5enzyme
LetermovirCytochrome P450 3A7enzyme
LetermovirCytochrome P450 3A43enzyme
DolutegravirUDP-glucuronosyltransferase 1-1enzyme
DolutegravirCytochrome P450 3A Subfamilyenzyme
DolutegravirIntegrasetarget
DolutegravirSolute carrier family 22 member 2transporter
DolutegravirUDP-glucuronosyltransferase 1-3enzyme
DolutegravirUDP-glucuronosyltransferase 1-9enzyme
DolutegravirATP-binding cassette sub-family G member 2transporter
DolutegravirSolute carrier family 22 member 6transporter
DolutegravirSolute carrier family 22 member 8transporter
DolutegravirP-glycoprotein 1transporter
RucaparibPoly [ADP-ribose] polymerase 1target
RucaparibPoly [ADP-ribose] polymerase 2target
RucaparibPoly [ADP-ribose] polymerase 3target
RucaparibCytochrome P450 2D6enzyme
RucaparibCytochrome P450 1A2enzyme
RucaparibCytochrome P450 3A4enzyme
RucaparibP-glycoprotein 1transporter
RucaparibATP-binding cassette sub-family G member 2transporter
RucaparibMultidrug and toxin extrusion protein 1transporter
RucaparibMultidrug and toxin extrusion protein 2transporter
RucaparibSolute carrier family 22 member 1transporter
RucaparibMultidrug resistance-associated protein 4transporter
RucaparibSolute carrier organic anion transporter family member 1B1transporter
RucaparibSolute carrier organic anion transporter family member 1B3transporter
RucaparibSolute carrier family 22 member 6transporter
RucaparibSolute carrier family 22 member 8transporter
RucaparibCytochrome P450 3A5enzyme
RucaparibCytochrome P450 3A7enzyme
RucaparibCytochrome P450 3A43enzyme
RucaparibCytochrome P450 2C19enzyme
RucaparibCytochrome P450 2C9enzyme
RucaparibCytochrome P450 2C8enzyme
RucaparibUDP-glucuronosyltransferase 1-1enzyme
BaricitinibSolute carrier family 22 member 8transporter
BaricitinibATP-binding cassette sub-family G member 2transporter
BaricitinibMultidrug and toxin extrusion protein 2transporter
BaricitinibCytochrome P450 3A4enzyme
BaricitinibTyrosine-protein kinase JAK1target
BaricitinibTyrosine-protein kinase JAK2target
BaricitinibSolute carrier family 22 member 6transporter
BaricitinibSolute carrier family 22 member 2transporter
BaricitinibSolute carrier organic anion transporter family member 1B3transporter
BaricitinibProtein-tyrosine kinase 2-betatarget
BaricitinibTyrosine-protein kinase JAK3target
BaricitinibP-glycoprotein 1transporter
ApalutamideAndrogen receptortarget
ApalutamideCytochrome P450 3A4enzyme
ApalutamideCytochrome P450 2C8enzyme
ApalutamideCytochrome P450 2C19enzyme
ApalutamideCytochrome P450 2C9enzyme
ApalutamideP-glycoprotein 1transporter
ApalutamideATP-binding cassette sub-family G member 2transporter
ApalutamideSolute carrier organic anion transporter family member 1B1transporter
ApalutamideSolute carrier family 22 member 2transporter
ApalutamideSolute carrier family 22 member 8transporter
ApalutamideMultidrug and toxin extrusion protein 2transporter
ApalutamideGABA(A) Receptortarget
ApalutamideMultidrug and toxin extrusion protein 1transporter
AvatrombopagATP-binding cassette sub-family G member 2target
AvatrombopagCytochrome P450 2C8enzyme
AvatrombopagCytochrome P450 2C9enzyme
AvatrombopagThrombopoietin receptortarget
AvatrombopagP-glycoprotein 1transporter
AvatrombopagSolute carrier family 22 member 8target
CefaclorPenicillin-binding protein 1Atarget
CefaclorSolute carrier family 15 member 1transporter
CefaclorSolute carrier family 15 member 2transporter
CefaclorPenicillin-binding protein 3target
CefaclorMyeloperoxidaseenzyme
CefaclorSolute carrier family 22 member 8transporter
CefaclorBile salt export pumptransporter
CefotiamPenicillin-binding protein 1Atarget
CefotiamSolute carrier family 22 member 6transporter
CefotiamSolute carrier family 22 member 8transporter
CeftibutenSolute carrier family 15 member 1transporter
CeftibutenSolute carrier family 15 member 2transporter
CeftibutenPeptidoglycan synthase FtsItarget
CeftibutenPenicillin-binding protein 1Atarget
CeftibutenPenicillin-binding protein 1Btarget
CeftibutenPenicillin-binding protein 2target
CeftibutenSolute carrier family 22 member 6transporter
CeftibutenSolute carrier family 22 member 8transporter
CeftizoximeSolute carrier family 15 member 1transporter
CeftizoximePenicillin-binding protein 1Atarget
CeftizoximePenicillin-binding protein 1Btarget
CeftizoximeSolute carrier family 22 member 6transporter
CeftizoximeSolute carrier family 22 member 8transporter
CeftizoximePeptidoglycan transpeptidasetarget
CeftizoximeD-alanyl-D-alanine carboxypeptidase DacCtarget
CefaloridineSolute carrier family 22 member 6transporter
CefaloridineSolute carrier family 22 member 8transporter
LeucovorinSolute carrier family 22 member 8transporter
Rosuvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
RosuvastatinCytochrome P450 2C9enzyme
RosuvastatinMultidrug resistance-associated protein 4transporter
RosuvastatinSolute carrier organic anion transporter family member 1A2transporter
RosuvastatinSolute carrier organic anion transporter family member 1B3transporter
RosuvastatinSolute carrier organic anion transporter family member 2B1transporter
RosuvastatinCystine/glutamate transportertransporter
RosuvastatinSolute carrier organic anion transporter family member 1B1transporter
RosuvastatinBile salt export pumptransporter
RosuvastatinATP-binding cassette sub-family G member 2transporter
RosuvastatinSerum albumincarrier
RosuvastatinCanalicular multispecific organic anion transporter 1transporter
RosuvastatinSolute carrier family 22 member 8transporter
RosuvastatinSodium/bile acid cotransportertransporter
RosuvastatinIntegrin alpha-Ltarget
RifampicinDNA-directed RNA polymerase subunit betatarget
RifampicinNuclear receptor subfamily 1 group I member 2target
RifampicinCytochrome P450 3A4enzyme
RifampicinCytochrome P450 1A2enzyme
RifampicinCytochrome P450 2C8enzyme
RifampicinUDP-glucuronosyltransferase 1-1enzyme
RifampicinCytochrome P450 2C9enzyme
RifampicinCytochrome P450 2B6enzyme
RifampicinCytochrome P450 2C19enzyme
RifampicinCanalicular multispecific organic anion transporter 2transporter
RifampicinMultidrug resistance-associated protein 5transporter
RifampicinP-glycoprotein 1transporter
RifampicinCanalicular multispecific organic anion transporter 1transporter
RifampicinSolute carrier organic anion transporter family member 2B1transporter
RifampicinBile salt export pumptransporter
RifampicinMultidrug resistance-associated protein 1transporter
RifampicinSolute carrier organic anion transporter family member 1A2transporter
RifampicinSolute carrier organic anion transporter family member 1B3transporter
RifampicinSolute carrier family 22 member 7transporter
RifampicinSolute carrier organic anion transporter family member 1B1transporter
RifampicinCytochrome P450 2A6enzyme
RifampicinCytochrome P450 2E1enzyme
RifampicinCytochrome P450 3A43enzyme
RifampicinCytochrome P450 3A7enzyme
RifampicinSolute carrier family 22 member 6transporter
RifampicinSolute carrier family 22 member 8transporter
RifampicinUDP-glucuronosyltransferase 1-9enzyme
RifampicinCytochrome P450 3A5enzyme
RifampicinSerum albumincarrier
Rifampicinalpha1-acid glycoproteincarrier
CabotegravirSolute carrier family 22 member 6transporter
CabotegravirSolute carrier family 22 member 8transporter
PradigastatSolute carrier family 22 member 8transporter
LansoprazolePotassium-transporting ATPase alpha chain 1target
LansoprazoleCytochrome P450 2C19enzyme
LansoprazoleCytochrome P450 2C9enzyme
LansoprazoleCytochrome P450 3A4enzyme
LansoprazoleP-glycoprotein 1transporter
LansoprazoleATP-binding cassette sub-family G member 2transporter
LansoprazoleCytochrome P450 1A1enzyme
LansoprazoleCytochrome P450 1B1enzyme
LansoprazoleCytochrome P450 2C18enzyme
LansoprazoleCytochrome P450 2C8enzyme
LansoprazoleCytochrome P450 2D6enzyme
LansoprazoleMicrotubule-associated protein tautarget
LansoprazoleSolute carrier family 22 member 8transporter
LansoprazoleSolute carrier family 22 member 1transporter
LansoprazoleSolute carrier family 22 member 2transporter
LansoprazoleSolute carrier family 22 member 3transporter
Acetylsalicylic acidProstaglandin G/H synthase 1target
Acetylsalicylic acidProstaglandin G/H synthase 2target
Acetylsalicylic acidAldo-keto reductase family 1 member C1target
Acetylsalicylic acidSolute carrier family 22 member 6transporter
Acetylsalicylic acidP-glycoprotein 1transporter
Acetylsalicylic acidCytochrome P450 2C19enzyme
Acetylsalicylic acidCytochrome P450 2C9enzyme
Acetylsalicylic acid5'-AMP-activated protein kinasetarget
Acetylsalicylic acidEndothelin-1 receptortarget
Acetylsalicylic acidCellular tumor antigen p53target
Acetylsalicylic acid78 kDa glucose-regulated proteintarget
Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
Acetylsalicylic acidCaspase-1target
Acetylsalicylic acidCaspase-3target
Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
Acetylsalicylic acidG1/S-specific cyclin-D1target
Acetylsalicylic acidMyc proto-oncogene proteintarget
Acetylsalicylic acidProliferating cell nuclear antigentarget
Acetylsalicylic acidCyclin Atarget
Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
Acetylsalicylic acidSolute carrier family 22 member 8transporter
PantoprazolePotassium-transporting ATPase alpha chain 1target
PantoprazoleCytochrome P450 2C19enzyme
PantoprazoleCytochrome P450 3A4enzyme
PantoprazoleP-glycoprotein 1transporter
PantoprazoleATP-binding cassette sub-family G member 2transporter
PantoprazoleSolute carrier family 22 member 8transporter
PantoprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
EsomeprazolePotassium-transporting ATPase alpha chain 1target
EsomeprazoleCytochrome P450 2C19enzyme
EsomeprazoleCytochrome P450 3A4enzyme
EsomeprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
EsomeprazoleP-glycoprotein 1transporter
EsomeprazoleSolute carrier family 22 member 8transporter
Pravastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
PravastatinSolute carrier organic anion transporter family member 2B1transporter
PravastatinP-glycoprotein 1transporter
PravastatinSolute carrier organic anion transporter family member 1A2transporter
PravastatinSolute carrier family 22 member 6transporter
PravastatinSolute carrier family 22 member 8transporter
PravastatinCanalicular multispecific organic anion transporter 1transporter
PravastatinSolute carrier family 22 member 11transporter
PravastatinATP-binding cassette sub-family G member 2transporter
PravastatinSolute carrier family 22 member 7transporter
PravastatinSolute carrier organic anion transporter family member 1B1transporter
PravastatinMonocarboxylate transporter 1transporter
PravastatinBile salt export pumptransporter
PravastatinSolute carrier organic anion transporter family member 1B3transporter
PravastatinHistone deacetylase 2target
TazobactamBeta-lactamase TEMtarget
TazobactamSolute carrier family 22 member 6transporter
TazobactamSolute carrier family 22 member 8transporter
TazobactamBeta-lactamase Ohio-1target
TazobactamBeta-lactamase SHV-1target
PretomanidDeazaflavin-dependent nitroreductaseenzyme
PretomanidSolute carrier family 22 member 8transporter
PretomanidCytochrome P450 3A4enzyme
PretomanidFatty acid synthetasetarget
PretomanidUncharacterized MFS-type transporter EfpAtarget
PretomanidNucleoid-associated protein Lsr2target
PretomanidCyd operon, Mycobacterium tuberculosistarget
PretomanidEnoyl-[acyl-carrier-protein] reductase [NADH]target
LatanoprostProstaglandin F2-alpha receptortarget
LatanoprostSolute carrier organic anion transporter family member 2A1transporter
LatanoprostSolute carrier family 22 member 6transporter
LatanoprostSolute carrier family 22 member 8transporter
LatanoprostCorneal esterasesenzyme
GemfibrozilPeroxisome proliferator-activated receptor alphatarget
GemfibrozilCytochrome P450 2C9enzyme
GemfibrozilCytochrome P450 2C8enzyme
GemfibrozilCytochrome P450 1A2enzyme
GemfibrozilCytochrome P450 2C19enzyme
GemfibrozilUDP-glucuronosyltransferase 1-1enzyme
GemfibrozilCytochrome P450 3A4enzyme
GemfibrozilUDP-glucuronosyltransferase 1-3enzyme
GemfibrozilSolute carrier organic anion transporter family member 1B1target
GemfibrozilUDP-glucuronosyltransferase 2B7enzyme
GemfibrozilUDP-glucuronosyltransferase 1-9enzyme
GemfibrozilUDP-glucuronosyltransferase 2B4enzyme
GemfibrozilUDP-glucuronosyltransferase 2B17enzyme
GemfibrozilSerum albumincarrier
GemfibrozilSolute carrier family 22 member 8target
GemfibrozilSolute carrier organic anion transporter family member 2B1target
GemfibrozilSolute carrier organic anion transporter family member 1B3target
DronedaroneAlpha-1A adrenergic receptortarget
DronedaroneBeta-1 adrenergic receptortarget
DronedaroneAlpha-1B adrenergic receptortarget
DronedaroneAlpha-1D adrenergic receptortarget
DronedaroneAlpha-2A adrenergic receptortarget
DronedaroneAlpha-2B adrenergic receptortarget
DronedaroneAlpha-2C adrenergic receptortarget
DronedaronePotassium voltage-gated channel subfamily H member 2target
DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Starget
DronedaroneVoltage-dependent L-type calcium channel subunit beta-1target
DronedaroneVoltage-dependent L-type calcium channel subunit beta-2target
DronedaroneVoltage-dependent L-type calcium channel subunit beta-3target
DronedaroneVoltage-dependent L-type calcium channel subunit beta-4target
DronedaroneCytochrome P450 2D6enzyme
DronedaroneCytochrome P450 3A4enzyme
DronedaroneP-glycoprotein 1transporter
DronedaronePotassium channel subfamily K member 2target
DronedaroneSerum albumincarrier
DronedaroneSolute carrier family 22 member 2transporter
DronedaroneSolute carrier family 22 member 1transporter
DronedaroneSolute carrier organic anion transporter family member 1B1transporter
DronedaroneSolute carrier organic anion transporter family member 1B3transporter
DronedaroneSolute carrier family 22 member 8transporter
DronedaroneCytochrome P450 3A5enzyme
DronedaroneCytochrome P450 2J2enzyme
DronedaroneThyroid hormone receptor alphatarget
DronedaroneSodium channel protein type 5 subunit alphatarget
DronedaroneG protein-activated inward rectifier potassium channel 1target
DronedaronePotassium voltage-gated channel subfamily KQT member 1target
DronedaroneInward rectifier potassium channeltarget
DronedaroneSodium/calcium exchanger 1target
DronedaronePotassium voltage-gated channel subfamily D member 3target
TafamidisTransthyretintarget
TafamidisSolute carrier family 22 member 6transporter
TafamidisSolute carrier family 22 member 8transporter
TafamidisATP-binding cassette sub-family G member 2transporter
RimegepantCalcitonin gene-related peptide type 1 receptortarget
RimegepantP-glycoprotein 1transporter
RimegepantATP-binding cassette sub-family G member 2transporter
RimegepantSolute carrier organic anion transporter family member 1B1transporter
RimegepantSolute carrier family 22 member 8transporter
RimegepantSolute carrier organic anion transporter family member 1B3transporter
RimegepantSolute carrier family 22 member 2transporter
RimegepantMultidrug and toxin extrusion protein 1transporter
RimegepantCytochrome P450 3A4enzyme
RimegepantCytochrome P450 2C9enzyme
FavipiravirRNA-directed RNA polymerase catalytic subunittarget
FavipiravirAldehyde oxidaseenzyme
FavipiravirXanthine dehydrogenase/oxidaseenzyme
FavipiravirCytochrome P450 2C8enzyme
FavipiravirSerum albumincarrier
Favipiraviralpha1-acid glycoproteincarrier
FavipiravirP-glycoprotein 1transporter
FavipiravirSolute carrier family 22 member 6transporter
FavipiravirSolute carrier family 22 member 8transporter
FavipiravirSolute carrier family 22 member 12transporter
FavipiravirCytochrome P450 2E1enzyme
OsilodrostatCytochrome P450 11B1, mitochondrialtarget
OsilodrostatCytochrome P450 11B2, mitochondrialtarget
OsilodrostatCytochrome P450 3A4enzyme
OsilodrostatCytochrome P450 2B6enzyme
OsilodrostatCytochrome P450 2D6enzyme
OsilodrostatUDP-glucuronosyltransferase 1-4enzyme
OsilodrostatUDP-glucuronosyltransferase 2B7enzyme
OsilodrostatUDP-glucuronosyltransferase 2B10enzyme
OsilodrostatCytochrome P450 3A5enzyme
OsilodrostatCytochrome P450 1A2enzyme
OsilodrostatCytochrome P450 2C19enzyme
OsilodrostatCytochrome P450 2E1enzyme
OsilodrostatUDP-glucuronosyltransferase 1A1enzyme
OsilodrostatSolute carrier organic anion transporter family member 1B1transporter
OsilodrostatSolute carrier family 22 member 1transporter
OsilodrostatSolute carrier family 22 member 2transporter
OsilodrostatSolute carrier family 22 member 6transporter
OsilodrostatSolute carrier family 22 member 8transporter
OsilodrostatMultidrug and toxin extrusion protein 1transporter
HydroflumethiazideSolute carrier family 12 member 1target
HydroflumethiazideSodium/potassium-transporting ATPase subunit alpha-1target
HydroflumethiazideCarbonic anhydrase 4target
HydroflumethiazideCalcium-activated potassium channel subunit alpha-1target
HydroflumethiazideCarbonic anhydrase 2target
HydroflumethiazideCarbonic anhydrase 1target
HydroflumethiazideCarbonic anhydrase 9target
HydroflumethiazideCarbonic anhydrase 12target
HydroflumethiazideSerum albumincarrier
HydroflumethiazideSolute carrier family 22 member 6transporter
HydroflumethiazideSolute carrier family 22 member 8transporter
HydroflumethiazideCarbonic anhydrase 7target
ArtesunateMalaria protein EXP-1target
ArtesunateCytochrome P450 2A6enzyme
ArtesunateUDP-glucuronosyltransferase 2B7enzyme
ArtesunateUDP-glucuronosyltransferase 1-9enzyme
ArtesunateATP-binding cassette sub-family G member 2transporter
ArtesunateP-glycoprotein 1transporter
ArtesunateSolute carrier organic anion transporter family member 1B1transporter
ArtesunateSolute carrier family 22 member 8transporter
ArtesunateSerum albumincarrier