Hypogonadism

DrugDrug NameDrug Description
DB00286Conjugated estrogensA mixture of estrogens used in estrogen replacement therapy for menopause and hypoestrogenism, used in the treatment of various malignancies, and used in the treatment of postmenopausal osteoporosis.
DB09381Esterified estrogensA female hormone used to treat conditions related to estrogen deficiency and moderate to severe vasomotor menopausal symptoms in women.
DB13954Estradiol cypionateAn estradiol prodrug used to treat vasomotor symptoms and hypoestrogenisms from hypogonadism.
DB13956Estradiol valerateAn estradiol prodrug used to treat some effects of menopause, hypoestrogenism, androgen dependant carcinoma of the prostate, and in combination products for endometriosis and contraception.
DB04574Estrone sulfateAn estrogen used as monotherapy or in several combination hormone replacement products for managing menopause symptoms and hormone disorders.
DB00044Lutropin alfaA form of recombinant human luteinizing hormone used to treat female infertility due to hypothalamic or pituitary insufficiency, or due to profound luteinizing hormone deficiency.
DB06285TeriparatideA recombinant parathyroid hormone used for the treatment of osteoporosis.
DrugDrug NameTargetType
DB00286Conjugated estrogensEstrogen receptor alphatarget
DB00286Conjugated estrogensCytochrome P450 3A4enzyme
DB00286Conjugated estrogensCytochrome P450 1A2enzyme
DB00286Conjugated estrogensCatechol O-methyltransferaseenzyme
DB00286Conjugated estrogensCanalicular multispecific organic anion transporter 2transporter
DB00286Conjugated estrogensMultidrug resistance-associated protein 4transporter
DB00286Conjugated estrogensMultidrug resistance-associated protein 1transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 1A2transporter
DB00286Conjugated estrogensSodium/bile acid cotransportertransporter
DB00286Conjugated estrogensSolute carrier family 22 member 10transporter
DB00286Conjugated estrogensSolute carrier family 22 member 8transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 1C1transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 1B1transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 2B1transporter
DB00286Conjugated estrogensP-glycoprotein 1transporter
DB00286Conjugated estrogensSolute carrier family 22 member 6transporter
DB00286Conjugated estrogensOrganic solute transporter subunit alphatransporter
DB00286Conjugated estrogensOrganic solute transporter subunit betatransporter
DB00286Conjugated estrogensCanalicular multispecific organic anion transporter 1transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 4A1transporter
DB00286Conjugated estrogensATP-binding cassette sub-family C member 11transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 1B3transporter
DB00286Conjugated estrogensSolute carrier family 22 member 11transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 3A1transporter
DB00286Conjugated estrogensATP-binding cassette sub-family G member 2transporter
DB00286Conjugated estrogensThyroxine-binding globulincarrier
DB00286Conjugated estrogensSex hormone-binding globulincarrier
DB00286Conjugated estrogensSerum albumincarrier
DB00286Conjugated estrogensEstrogen receptor betatarget
DB09381Esterified estrogensCytochrome P450 3A4enzyme
DB09381Esterified estrogensThyroxine-binding globulincarrier
DB13954Estradiol cypionateEstrogen receptor alphatarget
DB13954Estradiol cypionateNuclear receptor subfamily 1 group I member 2target
DB13954Estradiol cypionateSex hormone-binding globulincarrier
DB13954Estradiol cypionateEstrogen receptor betatarget
DB13954Estradiol cypionateCytochrome P450 1A2enzyme
DB13954Estradiol cypionateUDP-glucuronosyltransferase 1-1enzyme
DB13954Estradiol cypionateSerum albumincarrier
DB13954Estradiol cypionateFatty acid-binding protein, intestinalcarrier
DB13954Estradiol cypionateCytochrome P450 3A4enzyme
DB13954Estradiol cypionateCytochrome P450 3A5enzyme
DB13954Estradiol cypionateCytochrome P450 3A7enzyme
DB13954Estradiol cypionateSolute carrier family 22 member 2transporter
DB13954Estradiol cypionateSolute carrier family 22 member 1transporter
DB13954Estradiol cypionateSolute carrier family 22 member 3transporter
DB13954Estradiol cypionateSolute carrier organic anion transporter family member 2B1transporter
DB13954Estradiol cypionateSolute carrier organic anion transporter family member 1A2transporter
DB13954Estradiol cypionateMultidrug resistance-associated protein 7transporter
DB13954Estradiol cypionateSolute carrier family 22 member 11transporter
DB13954Estradiol cypionateATP-binding cassette sub-family G member 2transporter
DB13954Estradiol cypionateSolute carrier organic anion transporter family member 1B1transporter
DB13954Estradiol cypionateP-glycoprotein 1transporter
DB13954Estradiol cypionateCytochrome P450 1A1enzyme
DB13954Estradiol cypionateCytochrome P450 1B1enzyme
DB13954Estradiol cypionateCytochrome P450 2C19enzyme
DB13954Estradiol cypionateCytochrome P450 2C8enzyme
DB13954Estradiol cypionateCytochrome P450 2C9enzyme
DB13954Estradiol cypionateSolute carrier family 22 member 8transporter
DB13954Estradiol cypionateSolute carrier organic anion transporter family member 1B3transporter
DB13954Estradiol cypionateSolute carrier organic anion transporter family member 1C1transporter
DB13954Estradiol cypionateSolute carrier organic anion transporter family member 4A1transporter
DB13954Estradiol cypionateNeuronal acetylcholine receptor subunit alpha-4target
DB13954Estradiol cypionateNuclear receptor coactivator 2target
DB13954Estradiol cypionateG-protein coupled estrogen receptor 1target
DB13954Estradiol cypionateATP synthase subunit atarget
DB13954Estradiol cypionateBeclin-1target
DB13954Estradiol cypionateEstradiol 17-beta-dehydrogenase 2target
DB13954Estradiol cypionateEstrogen-related receptor gammatarget
DB13956Estradiol valerateEstrogen receptor alphatarget
DB13956Estradiol valerateNuclear receptor subfamily 1 group I member 2target
DB13956Estradiol valerateSex hormone-binding globulincarrier
DB13956Estradiol valerateEstrogen receptor betatarget
DB13956Estradiol valerateCytochrome P450 1A2enzyme
DB13956Estradiol valerateUDP-glucuronosyltransferase 1-1enzyme
DB13956Estradiol valerateSerum albumincarrier
DB13956Estradiol valerateFatty acid-binding protein, intestinalcarrier
DB13956Estradiol valerateCytochrome P450 3A4enzyme
DB13956Estradiol valerateCytochrome P450 3A5enzyme
DB13956Estradiol valerateCytochrome P450 3A7enzyme
DB13956Estradiol valerateSolute carrier family 22 member 2transporter
DB13956Estradiol valerateSolute carrier family 22 member 1transporter
DB13956Estradiol valerateSolute carrier family 22 member 3transporter
DB13956Estradiol valerateSolute carrier organic anion transporter family member 2B1transporter
DB13956Estradiol valerateSolute carrier organic anion transporter family member 1A2transporter
DB13956Estradiol valerateMultidrug resistance-associated protein 7transporter
DB13956Estradiol valerateSolute carrier family 22 member 11transporter
DB13956Estradiol valerateATP-binding cassette sub-family G member 2transporter
DB13956Estradiol valerateSolute carrier organic anion transporter family member 1B1transporter
DB13956Estradiol valerateP-glycoprotein 1transporter
DB13956Estradiol valerateCytochrome P450 1A1enzyme
DB13956Estradiol valerateCytochrome P450 1B1enzyme
DB13956Estradiol valerateCytochrome P450 2C19enzyme
DB13956Estradiol valerateCytochrome P450 2C8enzyme
DB13956Estradiol valerateCytochrome P450 2C9enzyme
DB13956Estradiol valerateSolute carrier family 22 member 8transporter
DB13956Estradiol valerateSolute carrier organic anion transporter family member 1B3transporter
DB13956Estradiol valerateSolute carrier organic anion transporter family member 1C1transporter
DB13956Estradiol valerateSolute carrier organic anion transporter family member 4A1transporter
DB13956Estradiol valerateNeuronal acetylcholine receptor subunit alpha-4target
DB13956Estradiol valerateNuclear receptor coactivator 2target
DB13956Estradiol valerateG-protein coupled estrogen receptor 1target
DB13956Estradiol valerateATP synthase subunit atarget
DB13956Estradiol valerateBeclin-1target
DB13956Estradiol valerateEstradiol 17-beta-dehydrogenase 2target
DB13956Estradiol valerateEstrogen-related receptor gammatarget
DB04574Estrone sulfateCytochrome P450 1A2enzyme
DB04574Estrone sulfateCytochrome P450 3A4enzyme
DB04574Estrone sulfateEstrogen receptor alphatarget
DB04574Estrone sulfateEstrogen receptor betatarget
DB04574Estrone sulfateSex hormone-binding globulincarrier
DB04574Estrone sulfateSerum albumincarrier
DB04574Estrone sulfateCytochrome P450 2C9enzyme
DB04574Estrone sulfateMultidrug and toxin extrusion protein 1transporter
DB04574Estrone sulfateMultidrug and toxin extrusion protein 2transporter
DB00044Lutropin alfaLutropin-choriogonadotropic hormone receptortarget
DB06285TeriparatideParathyroid hormone/parathyroid hormone-related peptide receptortarget
DrugDrug NamePhaseStatusCount
DB00203Sildenafil0Terminated1
DB00624Testosterone0Terminated1
DB00624Testosterone0Withdrawn1
DB11906Acyline1Completed2
DB01126Dutasteride1Completed1
DB01216Finasteride1Completed1
DB00644Gonadorelin1Completed1
DB01026Ketoconazole1Completed1
DB11172Sesame oil1Completed1
DB00624Testosterone1Completed9
DB05720Testosterone1Completed1
DB00624Testosterone1Recruiting1
DB00624Testosterone1Terminated1
DB00624Testosterone1Withdrawn1
DB13943Testosterone cypionate1Completed1
DB13944Testosterone enanthate1Completed2
DB00624Testosterone1 / 2Completed1
DB13944Testosterone enanthate1 / 2Completed1
DB13946Testosterone undecanoate1 / 2Completed1
DB00630Alendronic acid2Suspended1
DB01217Anastrozole2Completed3
DB00882Clomifene2Completed2
DB01126Dutasteride2Completed2
DB06735Enclomiphene2Completed1
DB01216Finasteride2Recruiting1
DB06640Fispemifene2Completed3
DB09024Follitropin2Terminated1
DB00644Gonadorelin2Recruiting1
DB00644Gonadorelin2Terminated1
DB00007Leuprolide2Completed1
DB00052Somatotropin2Completed1
DB02901Stanolone2Unknown Status1
DB00624Testosterone2Completed19
DB05720Testosterone2Completed1
DB00624Testosterone2Suspended1
DB00624Testosterone2Terminated1
DB00624Testosterone2Unknown Status1
DB13944Testosterone enanthate2Completed3
DB13944Testosterone enanthate2Recruiting1
DB13946Testosterone undecanoate2Completed6
DB00624Testosterone2 / 3Completed1
DB00624Testosterone2 / 3Recruiting1
DB13943Testosterone cypionate2 / 3Recruiting1
DB13946Testosterone undecanoate2 / 3Completed1
DB00630Alendronic acid3Completed1
DB00026Anakinra3Completed1
DB00169Cholecalciferol3Recruiting1
DB09126Chorionic Gonadotropin (Human)3Completed2
DB09066Corifollitropin alfa3Completed1
DB00783Estradiol3Completed2
DB09024Follitropin3Completed1
DB14741Luteinizing hormone3Completed1
DB00044Lutropin alfa3Completed1
DB00331Metformin3Completed1
DB09153Sodium chloride3Completed1
DB00624Testosterone3Completed12
DB05720Testosterone3Completed2
DB00624Testosterone3Not Yet Recruiting1
DB00624Testosterone3Recruiting1
DB00624Testosterone3Unknown Status3
DB13944Testosterone enanthate3Completed2
DB13946Testosterone undecanoate3Completed4
DB13946Testosterone undecanoate3Unknown Status1
DB01217Anastrozole4Recruiting1
DB00169Cholecalciferol4Completed1
DB01126Dutasteride4Completed2
DB00783Estradiol4Completed1
DB06655Liraglutide4Completed1
DB00624Testosterone4Completed15
DB00624Testosterone4Recruiting3
DB00624Testosterone4Terminated3
DB00624Testosterone4Unknown Status3
DB00624Testosterone4Withdrawn4
DB13946Testosterone undecanoate4Completed1
DB13946Testosterone undecanoate4Terminated1
DB06825Triptorelin4Completed1
DB00862Vardenafil4Terminated1
DB11094Vitamin D4Completed1
DB11906AcylineNot AvailableCompleted1
DB11906AcylineNot AvailableRecruiting1
DB01217AnastrozoleNot AvailableRecruiting1
DB09126Chorionic Gonadotropin (Human)Not AvailableActive Not Recruiting1
DB09126Chorionic Gonadotropin (Human)Not AvailableCompleted1
DB00882ClomifeneNot AvailableRecruiting1
DB00644GonadorelinNot AvailableCompleted2
DB01026KetoconazoleNot AvailableCompleted1
DB00007LeuprolideNot AvailableCompleted2
DB14741Luteinizing hormoneNot AvailableCompleted1
DB01132PioglitazoneNot AvailableTerminated1
DB00624TestosteroneNot AvailableCompleted7
DB05720TestosteroneNot AvailableCompleted2
DB00624TestosteroneNot AvailableRecruiting1
DB00624TestosteroneNot AvailableUnknown Status2
DB13946Testosterone undecanoateNot AvailableCompleted4
DB13946Testosterone undecanoateNot AvailableUnknown Status1