Cupric oxide

Identification

Name
Cupric oxide
Accession Number
DB11134
Type
Small Molecule
Groups
Approved
Description

Cupric oxide, or copper (II) oxide, is an inorganic compound with the chemical formula CuO. Cupric oxide is used as a precursor in many copper-containing products such as wood preservatives and ceramics. Cupric oxide may be found in over-the-counter vitamin-mineral supplements as a source of Copper. The mean daily dietary intake of copper in adults ranges between 0.9 and 2.2 mg [3]. Common routes of cupric oxide exposure include ingestion, dermal exposure and inhalation. Copper(II) oxide nanoparticles (NPCuO) have industrial applications as antimicrobial agents in textiles and paints, and catalysts in organic synthesis [1]. They may also be produced from electronic wastes. Cupric oxide poses potential health and environmental concern due to toxic and mutagenic particles generating reactive oxygen species [1].

Structure
Thumb
Synonyms
  • Cuprous Oxide
  • Cuprum oxydatum nigrum
External IDs
NSC-83537
Active Moieties
NameKindUNIICASInChI Key
Copperunknown789U1901C57440-50-8RYGMFSIKBFXOCR-UHFFFAOYSA-N
Cupric cationionicFV4Y0JO2CX15158-11-9JPVYNHNXODAKFH-UHFFFAOYSA-N
Product Images
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Balance Ace - CapCupric oxide (1 mg) + Ascorbic acid (250 mg) + Beta carotene (10000 unit) + DL-alpha tocopheryl acetate (200 unit) + Manganese (1.5 mg) + Sodium selenate (15 mcg) + Zinc (7.5 mg)CapsuleOralPharmavite1996-09-062002-07-25Canada
Calcium PlusCupric oxide (1 mg) + Calcium (600 mg) + Cholecalciferol (200 unit) + Magnesium (50 mg) + Manganese (1.8 mg) + Zinc (7.5 mg)TabletOralLaboratoire Riva IncNot applicableNot applicableCanada
Cell-wise Natural SourceCupric oxide (1 mg) + Ascorbic acid (200 mg) + Beta carotene (5000 unit) + Calcium (82.5 mg) + Manganese (1.5 mg) + Sodium selenate (25 mcg) + Vitamin E (200 unit) + Zinc (7.5 mg)TabletOralMelaleuca, Inc.1998-05-262005-06-28Canada
Central-vite 18 EssentialCupric oxide (2 mg) + Ascorbic acid (90 mg) + Beta carotene (3000 unit) + Biotin (45 mcg) + Calcium (175 mg) + Calcium Phosphate (125 mg) + Cholecalciferol (400 unit) + Cyanocobalamin (9 mcg) + Ferrous fumarate (10 mg) + Folic Acid (0.4 mg) + Magnesium (100 mg) + Nicotinamide (40 mg) + Calcium pantothenate (10 mg) + Potassium Iodide (0.15 mg) + Pyridoxine hydrochloride (3 mg) + Riboflavin (3.2 mg) + Thiamine mononitrate (2.25 mg) + Vitamin A (2000 unit) + alpha-Tocopherol acetate (25 unit)TabletOralVita Health Products Inc1998-04-242002-07-31Canada
Century CompleteCupric oxide (2 mg) + Ascorbic acid (90 mg) + Beta carotene (3000 unit) + Biotin (45 mcg) + Calcium (175 mg) + Calcium Phosphate (125 mg) + Cyanocobalamin (9 mcg) + Ferrous fumarate (10 mg) + Folic Acid (.4 mg) + Magnesium (100 mg) + Nicotinamide (40 mg) + Calcium pantothenate (10 mg) + Potassium Iodide (.15 mg) + Pyridoxine hydrochloride (3 mg) + Riboflavin (3.2 mg) + Thiamine mononitrate (2.25 mg) + Vitamin A (2000 unit) + Vitamin D (400 unit) + alpha-Tocopherol acetate (25 unit)TabletOralVita Health Products Inc1998-03-172002-07-31Canada
Children's Chewable Multivitamin and MultimineralCupric oxide (2 mg) + Ascorbic acid (60 mg) + Beta carotene (250 unit) + Biotin (20 mcg) + Calcium (162 mg) + Calcium Phosphate (125 mg) + Cyanocobalamin (5 mcg) + Ferrous fumarate (4 mg) + Folic Acid (0.3 mg) + Nicotinamide (15 mg) + Calcium pantothenate (5 mg) + Potassium Iodide (0.15 mg) + Pyridoxine hydrochloride (1.7 mg) + Riboflavin (1.4 mg) + Thiamine mononitrate (1.2 mg) + Vitamin A (2750 unit) + Vitamin D (400 unit) + Vitamin E (15 unit)TabletOralJamieson Laboratories Ltd2006-09-202009-07-29Canada
CitraNatal 90 DHACupric oxide (2 mg/1) + Ascorbic acid (120 mg/1) + Calcium citrate tetrahydrate (160 mg/1) + Docusate sodium (50 mg/1) + Folic Acid (1 mg/1) + Iron (90 mg/1) + Nicotinamide (20 mg/1) + Potassium triiodide (150 ug/1) + Pyridoxine hydrochloride (20 mg/1) + Riboprine (3.4 mg/1) + Thiamine chloride (3 mg/1) + Vitamin D (400 [iU]/1) + Zinc oxide (25 mg/1) + alpha-Tocopherol acetate (30 [iU]/1)TabletOralMission Pharmacal2010-02-01Not applicableUs
CitraNatal DHACupric oxide (2 mg/1) + Ascorbic acid (120 mg/1) + Calcium citrate tetrahydrate (125 mg/1) + Docusate sodium (50 mg/1) + Folic Acid (1 mg/1) + Iron (27 mg/1) + Nicotinamide (20 mg/1) + Potassium Iodide (150 mg/1) + Pyridoxine hydrochloride (20 mg/1) + Riboflavin (3.4 mg/1) + Thiamine chloride (3 mg/1) + Vitamin D (400 [iU]/1) + Zinc oxide (25 mg/1) + alpha-Tocopherol acetate (30 [iU]/1)TabletOralMission Pharmacal2007-11-20Not applicableUs
Complete Multivitamins and Minerals for ChildrenCupric oxide (1 mg) + Biotin (30 mcg) + Calcium (160 mg) + Calcium Phosphate (125 mg) + Cholecalciferol (400 unit) + Cyanocobalamin (3 mcg) + Ferrous fumarate (4 mg) + Folic Acid (0.1 mg) + Nicotinamide (15 mg) + Calcium pantothenate (10 mg) + Pyridoxine hydrochloride (1 mg) + Riboflavin (1.5 mg) + Sodium ascorbate (50 mg) + Thiamine mononitrate (1.5 mg) + Vitamin A palmitate (5000 unit) + alpha-Tocopherol acetate (10 unit)TabletOralQuest Vitamins A Div Of Purity Life Health Products2001-01-312004-06-29Canada
Coppermagic Pain Relief BalmCupric oxide (.4 g/100g) + Eucalyptus globulus leaf (.5 g/100g) + Urea (1 g/100g)CreamTopicalShanghai Weierya Daily Chemicals Factory2017-02-172017-04-17Us
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Active FECupric oxide (1 mg/1) + Ascorbic acid (160 mg/1) + Beta carotene (2100 [iU]/1) + Cholecalciferol (400 [iU]/1) + Cyanocobalamin (30 ug/1) + DL-alpha tocopheryl acetate (40 [iU]/1) + Folic Acid (1250 ug/1) + Iron (75 mg/1) + Magnesium oxide (30 mg/1) + Nicotinamide (20 mg/1) + Pyridoxine hydrochloride (20 mg/1) + Riboflavin (4 mg/1) + Thiamine hydrochloride (4 mg/1) + Zinc oxide (20 mg/1)TabletOralGm Pharmaceuticals2013-11-11Not applicableUs
BacminCupric oxide (3 mg/1) + Ascorbic acid (500 mg/1) + Biotin (150 ug/1) + Chromium Cr-51 chloride (0.1 mg/1) + Cyanocobalamin (50 ug/1) + Ferrous fumarate (27 mg/1) + Flavone (50 mg/1) + Folic Acid (1 mg/1) + Magnesium oxide (50 mg/1) + Manganese gluconate (5 mg/1) + Nicotinamide (100 mg/1) + Calcium pantothenate (25 mg/1) + Pyridoxine hydrochloride (25 mg/1) + Riboflavin (20 mg/1) + Selenomethionine (50 ug/1) + Thiamine mononitrate (20 mg/1) + Vitamin A acetate (2000 [iU]/1) + Zinc oxide (22.5 mg/1) + alpha-Tocopherol acetate (30 [iU]/1)Tablet, coatedOralMarnel Pharmaceuticals, Llc2000-04-01Not applicableUs
Bal-Care DHACupric oxide (2 mg/1) + Ascorbic acid (120 mg/1) + Beta carotene (2850 [iU]/1) + Calcium Carbonate (219 mg/1) + Cholecalciferol (840 [iU]/1) + Cyanocobalamin (.012 mg/1) + DL-alpha tocopheryl acetate (3 mg/1) + Folic Acid (1 mg/1) + Iodine (.223 mg/1) + Iron saccharate (1.35 mg/1) + Magnesium oxide (25 mg/1) + Nicotinamide (20 mg/1) + Omega-3 fatty acids (430 mg/1) + Pyridoxine hydrochloride (50 mg/1) + Riboflavin (4 mg/1) + Sodium feredetate (25.65 mg/1) + Thiamine mononitrate (1.8 mg/1) + Zinc oxide (25 mg/1)KitPru Gen Pharmaceuticals2012-05-01Not applicableUs
Bal-Care DHA EssentialCupric oxide (2 mg/1) + Ascorbic acid (120 mg/1) + Beta carotene (2850 [iU]/1) + Calcium Carbonate (219 mg/1) + Cholecalciferol (840 [iU]/1) + Cyanocobalamin (.012 mg/1) + DL-alpha tocopheryl acetate (3 mg/1) + Folic Acid (1 mg/1) + Iodine (.223 mg/1) + Iron saccharate (1.35 mg/1) + Magnesium oxide (25 mg/1) + Nicotinamide (20 mg/1) + Omega-3 fatty acids (374 mg/1) + Pyridoxine hydrochloride (50 mg/1) + Riboflavin (4 mg/1) + Sodium feredetate (25.65 mg/1) + Thiamine mononitrate (1.8 mg/1) + Zinc oxide (25 mg/1)KitPru Gen Pharmaceuticals2012-05-01Not applicableUs
Cavan AlphaCupric oxide (2 mg/1) + Ascorbic acid (120 mg/1) + Beta carotene (3000 [iU]/1) + Calcium Carbonate (230 mg/1) + Cholecalciferol (800 [iU]/1) + Cyanocobalamin (12 ug/1) + DL-alpha tocopheryl acetate (3 mg/1) + Folic Acid (1 mg/1) + Iodine (220 ug/1) + Iron (27 mg/1) + Magnesium oxide (25 mg/1) + Nicotinamide (20 mg/1) + Omega-3 fatty acids (300 mg/1) + Pyridoxine hydrochloride (50 mg/1) + Riboflavin (4 mg/1) + Thiamine mononitrate (1.8 mg/1) + Zinc oxide (25 mg/1)KitOralSeton Pharmaceuticals2010-07-012013-09-30Us
Cavan Folate DHACupric oxide (2 mg/1) + Cupric oxide (2 mg/1) + Ascorbic acid (70 mg/1) + Ascorbic acid (70 mg/1) + Beta carotene (2700 [iU]/1) + Beta carotene (2700 [iU]/1) + Calcium Carbonate (100 mg/1) + Calcium Carbonate (100 mg/1) + Cholecalciferol (400 [iU]/1) + Cholecalciferol (400 [iU]/1) + Cyanocobalamin (12 ug/1) + Cyanocobalamin (12 ug/1) + DL-alpha tocopheryl acetate (30 [iU]/1) + DL-alpha tocopheryl acetate (30 [iU]/1) + Doconexent (250 mg/1) + Doconexent (250 mg/1) + Ferrous fumarate (65 mg/1) + Ferrous fumarate (65 mg/1) + Folic Acid (1 mg/1) + Folic Acid (1 mg/1) + Magnesium oxide (25 mg/1) + Magnesium oxide (25 mg/1) + Nicotinamide (18 mg/1) + Nicotinamide (18 mg/1) + Pyridoxine hydrochloride (2.5 mg/1) + Pyridoxine hydrochloride (2.5 mg/1) + Riboflavin (1.8 mg/1) + Riboflavin (1.8 mg/1) + Thiamine mononitrate (1.6 mg/1) + Thiamine mononitrate (1.6 mg/1) + Zinc oxide (25 mg/1) + Zinc oxide (25 mg/1)KitSeton Pharmaceuticals2010-06-042012-03-31Us
Cavan Folate DHACupric oxide (2 mg/1) + Cupric oxide (2 mg/1) + Ascorbic acid (70 mg/1) + Ascorbic acid (70 mg/1) + Beta carotene (2700 [iU]/1) + Beta carotene (2700 [iU]/1) + Calcium Carbonate (100 mg/1) + Calcium Carbonate (100 mg/1) + Cholecalciferol (400 [iU]/1) + Cholecalciferol (400 [iU]/1) + Cyanocobalamin (12 ug/1) + Cyanocobalamin (12 ug/1) + DL-alpha tocopheryl acetate (30 [iU]/1) + DL-alpha tocopheryl acetate (30 [iU]/1) + Doconexent (250 mg/1) + Doconexent (250 mg/1) + Ferrous fumarate (65 mg/1) + Ferrous fumarate (65 mg/1) + Folic Acid (1 mg/1) + Folic Acid (1 mg/1) + Magnesium oxide (25 mg/1) + Magnesium oxide (25 mg/1) + Nicotinamide (18 mg/1) + Nicotinamide (18 mg/1) + Pyridoxine hydrochloride (2.5 mg/1) + Pyridoxine hydrochloride (2.5 mg/1) + Riboflavin (1.8 mg/1) + Riboflavin (1.8 mg/1) + Thiamine mononitrate (1.6 mg/1) + Thiamine mononitrate (1.6 mg/1) + Zinc oxide (25 mg/1) + Zinc oxide (25 mg/1)KitSeton Pharmaceuticals2010-06-042012-03-31Us
Cavan Folate OBCupric oxide (2 mg/1) + Ascorbic acid (70 mg/1) + Beta carotene (2700 [iU]/1) + Calcium Carbonate (100 mg/1) + Cholecalciferol (400 [iU]/1) + Cyanocobalamin (12 ug/1) + DL-alpha tocopheryl acetate (30 [iU]/1) + Ferrous fumarate (65 mg/1) + Folic Acid (1 mg/1) + Magnesium oxide (25 mg/1) + Nicotinamide (18 mg/1) + Pyridoxine hydrochloride (2.5 mg/1) + Riboflavin (1.8 mg/1) + Thiamine mononitrate (1.6 mg/1) + Zinc oxide (25 mg/1)TabletOralSeton Pharmaceuticals2010-08-232012-05-31Us
CitraNatal 90 DHACupric oxide (2 mg/1) + Ascorbic acid (120 mg/1) + Calcium citrate tetrahydrate (159 mg/1) + Docusate sodium (50 mg/1) + Ferrous gluconate dihydrate (5 mg/1) + Folic Acid (1 mg/1) + Iron (85 mg/1) + Nicotinamide (20 mg/1) + Potassium Iodide (150 ug/1) + Pyridoxine hydrochloride (20 mg/1) + Riboflavin (3.4 mg/1) + Thiamine chloride (3 mg/1) + Thiamine mononitrate (4.54 mg/1) + Vitamin D (400 [iU]/1) + Zinc oxide (25 mg/1) + alpha-Tocopherol acetate (30 [iU]/1)TabletOralMission Pharmacal Company2014-04-11Not applicableUs
CitraNatal DHACupric oxide (2 mg/1) + Ascorbic acid (120 mg/1) + Calcium citrate tetrahydrate (124 mg/1) + Doconexent (250 mg/1) + Docusate sodium (50 mg/1) + Folic Acid (1 mg/1) + Icosapent (0.625 mg/1) + Iron (27 mg/1) + Nicotinamide (20 mg/1) + Potassium Iodide (150 mg/1) + Pyridoxine hydrochloride (20 mg/1) + Riboflavin (3.4 mg/1) + Thiamine chloride (3 mg/1) + Vitamin D (400 [iU]/1) + Zinc oxide (25 mg/1) + alpha-Tocopherol acetate (30 [iU]/1)KitMission Pharmacal Company2014-05-22Not applicableUs
Categories
UNII
V1XJQ704R4
CAS number
1317-38-0
Weight
Average: 79.545
Monoisotopic: 78.924513
Chemical Formula
CuO
InChI Key
KKCXRELNMOYFLS-UHFFFAOYSA-N
InChI
InChI=1S/Cu.O/q+2;-2
IUPAC Name
copper(2+) ion oxidandiide
SMILES
[O--].[Cu++]

Pharmacology

Indication

No FDA- or EMA-approved therapeutic indications.

Pharmacodynamics

For pharmacodynamic information of copper, refer to drug entry for Copper. Copper(II) oxide nanoparticles are known to generate reactive oxygen species (ROS), leading to cytotoxicity [1]. In a comparative toxicity assay, nanoparticles caused significant mitochondrial depolarization leading to DNA damage [1]. In the human skin organ culture study, topical application of copper oxide (CuO) nanoparticles induced inflammatory cytokine secretion and necrosis in vitro, indicating that the nanoparticles may adhere to the skin surface and react with the local acidic environment [2].

Mechanism of action

For pharmacodynamic information of copper, refer to drug entry for Copper. Copper(II) oxide nanoparticles generate DNA-damaging reactive oxygen species at the nanoparticle surface or in solution by copper dissolved from the nanoparticle surface via Fenton-like reactions [1]. In presence of H2O2, ascorbate, or both, copper (II) oxide generates hydroxyl radical, ascorbyl radical, and superoxide anion that interact with DNA, proteins, and lipids cause oxidative damage and cell death [1].

Absorption

Following oral administration, copper is mainly absorbed through the gastrointestinal tract from the stomach, duodenum, and jejunum. All other intakes of copper (inhalation and dermal) are insignificant in comparison to the oral route. The bioavailability of copper from cupric oxide depends on the solubilization of the oxide in the gastrointestinal tract [4]. According to studies on cattle and swine, copper oxide displays low absorption rate and high excretion rate [3]. In rats exposed to aerosols containing 50-80 mg/m^3, pulmonary uptake of copper oxide occurred [3].

Volume of distribution

Following exposure to cupric oxide aerosols containing 50-80 mg/m^3 in rats, particles were found in plasma 6 hours post-exposure and copper oxide was also observed in the proximal convoluted tubules of the kidney [3].

Protein binding

Once dissociated, copper is known to bind to serum albumin, ceruloplasmin, and other low-molecular weight complexes [3].

Metabolism

Cupric oxide may dissolve in acids including hydrochloric acid to form copper (II) chloride [4]. As an inorganic compound, cupric oxide is unlikely to undergo biological degradation.

Route of elimination

Copper undergoes biliary excretion [3].

Half life

No pharmacokinetic data available.

Clearance

No pharmacokinetic data available.

Toxicity

Copper toxicity involves gastrointestinal irritation and liver and kidney toxicity. Reported No-Observed-Adverse-Effect-Levels (NOAELs) of copper are in the range of 23-104 mg/kg bw/day, but kidney effects have been shown in male rats at levels as low as 10 mg/kg bw/day [4]. Severe intoxication is associated with serum copper levels greater than 500 mcg/dL. The estimated lethal dose in an untreated adult is 10 to 20 g copper [3].

Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
  1. Angele-Martinez C, Nguyen KV, Ameer FS, Anker JN, Brumaghim JL: Reactive oxygen species generation by copper(II) oxide nanoparticles determined by DNA damage assays and EPR spectroscopy. Nanotoxicology. 2017 Mar;11(2):278-288. doi: 10.1080/17435390.2017.1293750. [PubMed:28248593]
  2. Cohen D, Soroka Y, Ma'or Z, Oron M, Portugal-Cohen M, Bregegere FM, Berhanu D, Valsami-Jones E, Hai N, Milner Y: Evaluation of topically applied copper(II) oxide nanoparticle cytotoxicity in human skin organ culture. Toxicol In Vitro. 2013 Feb;27(1):292-8. doi: 10.1016/j.tiv.2012.08.026. Epub 2012 Aug 29. [PubMed:22954531]
  3. COPPER(II) OXIDE - National Library of Medicine HSDB Database - Toxnet [Link]
  4. European Food Safety Authority (EFSA): Copper(II) oxide as a source of copper added for nutritional purposes [Link]
External Links
PubChem Compound
164827
PubChem Substance
347827912
ChemSpider
144499
ChEBI
75955
ChEMBL
CHEMBL1909057
Wikipedia
Copper(II)_oxide
MSDS
Download (47.2 KB)

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedTreatmentHyperemesis Gravidarum / Morning Sickness / Nausea / Pregnancy / Vomiting1
4CompletedTreatmentHyperpigmentation1
4CompletedTreatmentPregnancy1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
CreamTopical
Capsule, gelatin coatedOral
Tablet, coatedOral
CapsuleOral
TabletOral
Kit100 mg/1
Tablet, film coatedOral
KitOral
Tablet, chewableOral
Capsule, liquid filledOral
Kit
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
PropertyValueSource
melting point (°C)Decomposes at 1326MSDS, National Library of Medicine HSDB Database
boiling point (°C)Decomposes at 1026National Library of Medicine HSDB Database
water solubilityInsolubleMSDS
Predicted Properties
PropertyValueSource
Water Solubility270.0 mg/mLALOGPS
logP-1.3ALOGPS
logP-0.65ChemAxon
logS0.53ALOGPS
pKa (Strongest Acidic)15.7ChemAxon
pKa (Strongest Basic)-1.8ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count1ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity13.11 m3·mol-1ChemAxon
Polarizability0.95 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Taxonomy

Description
This compound belongs to the class of inorganic compounds known as transition metal oxides. These are inorganic compounds containing an oxygen atom of an oxidation state of -2, in which the heaviest atom bonded to the oxygen is a transition metal.
Kingdom
Inorganic compounds
Super Class
Mixed metal/non-metal compounds
Class
Transition metal organides
Sub Class
Transition metal oxides
Direct Parent
Transition metal oxides
Alternative Parents
Inorganic oxides / Inorganic copper salts
Substituents
Transition metal oxide / Inorganic copper salt / Inorganic oxide / Inorganic salt
Molecular Framework
Not Available
External Descriptors
inorganic oxide (CHEBI:75955)

Carriers

Kind
Protein
Organism
Human
Pharmacological action
Unknown
Actions
Binder
General Function
Toxic substance binding
Specific Function
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloid...
Gene Name
ALB
Uniprot ID
P02768
Uniprot Name
Serum albumin
Molecular Weight
69365.94 Da
References
  1. COPPER(II) OXIDE - National Library of Medicine HSDB Database - Toxnet [Link]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
Actions
Binder
General Function
Ferroxidase activity
Specific Function
Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iro...
Gene Name
CP
Uniprot ID
P00450
Uniprot Name
Ceruloplasmin
Molecular Weight
122204.45 Da
References
  1. COPPER(II) OXIDE - National Library of Medicine HSDB Database - Toxnet [Link]

Drug created on December 03, 2015 09:51 / Updated on November 02, 2018 07:07