Unstable Angina Pectoris

Also known as: Angina Pectoris, Unstable / Angina Unstable / Unstable Angina (UA) / Angina, Unstable / Unstable Angina / Accelerated angina / Intermediate coronary syndrome / Angina pectoris unstable / Angina at rest / Crescendo angina / Angina worsened

DrugDrug NameDrug Description
DB00945Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
DB09302AlirocumabA PCSK9 inhibitor used as an adjunct to manage heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease in patients who require additional lowering of LDL-cholesterol (LDL-C).
DB00758ClopidogrelAn antiplatelet agent used to prevent blood clots in peripheral vascular disease, coronary artery disease, and cerebrovascular disease.
DB06779DalteparinA low molecular weight heparin used for the prophylaxis of thrombotic events in certain patients and prevent acute cardiac ischemic events in patients with unstable angina and non-Q-wave myocardial infarction.
DB00569FondaparinuxAn anticoagulant used to prevent venous thromboembolism, to treat deep vein thrombosis, and to improve survival following myocardial infarction.
DB01109HeparinAn anticoagulant indicated for thromboprophylaxis and to treat thrombosis associated with a variety of conditions such as pulmonary embolism and atrial fibrillation.
DB08813NadroparinA low molecular weight heparin used for the prophylaxis of thrombotic events and deep vein thrombosis, and prevent unstable angina and non-Q-wave myocardial infarction.
DB00775TirofibanA platelet aggregation inhibitor used to prevent thrombotic events in non-ST elevated acute coronary syndrome.
DB00661VerapamilA calcium channel blocker used for the short-term treatment of angina, arrhythmia, and hypertension.
DrugDrug NameTargetType
DB00945Acetylsalicylic acidProstaglandin G/H synthase 1target
DB00945Acetylsalicylic acidProstaglandin G/H synthase 2target
DB00945Acetylsalicylic acidAldo-keto reductase family 1 member C1target
DB00945Acetylsalicylic acidSolute carrier family 22 member 6transporter
DB00945Acetylsalicylic acidP-glycoprotein 1transporter
DB00945Acetylsalicylic acidCytochrome P450 2C19enzyme
DB00945Acetylsalicylic acidCytochrome P450 2C9enzyme
DB00945Acetylsalicylic acid5'-AMP-activated protein kinasetarget
DB00945Acetylsalicylic acidEndothelin-1 receptortarget
DB00945Acetylsalicylic acidCellular tumor antigen p53target
DB00945Acetylsalicylic acid78 kDa glucose-regulated proteintarget
DB00945Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
DB00945Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
DB00945Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
DB00945Acetylsalicylic acidCaspase-1target
DB00945Acetylsalicylic acidCaspase-3target
DB00945Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00945Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
DB00945Acetylsalicylic acidG1/S-specific cyclin-D1target
DB00945Acetylsalicylic acidMyc proto-oncogene proteintarget
DB00945Acetylsalicylic acidProliferating cell nuclear antigentarget
DB00945Acetylsalicylic acidCyclin Atarget
DB00945Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
DB00945Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
DB00945Acetylsalicylic acidSolute carrier family 22 member 8transporter
DB09302AlirocumabProprotein convertase subtilisin/kexin type 9target
DB00758ClopidogrelP2Y purinoceptor 12target
DB00758ClopidogrelCytochrome P450 3A4enzyme
DB00758ClopidogrelCytochrome P450 2B6enzyme
DB00758ClopidogrelCytochrome P450 3A5enzyme
DB00758ClopidogrelCytochrome P450 2C19enzyme
DB00758ClopidogrelCytochrome P450 2C9enzyme
DB00758ClopidogrelCytochrome P450 1A2enzyme
DB00758ClopidogrelCytochrome P450 2C8enzyme
DB00758ClopidogrelLiver carboxylesterase 1enzyme
DB00758ClopidogrelP-glycoprotein 1transporter
DB00758ClopidogrelSolute carrier family 22 member 1transporter
DB00758ClopidogrelSolute carrier family 22 member 2transporter
DB06779DalteparinVascular endothelial growth factor Atarget
DB06779DalteparinTissue factor pathway inhibitortarget
DB06779DalteparinHeparanaseenzyme
DB06779DalteparinAntithrombin-IIItarget
DB06779DalteparinP-selectintarget
DB00569FondaparinuxAntithrombin-IIItarget
DB00569FondaparinuxCoagulation factor Xtarget
DB01109HeparinAntithrombin-IIItarget
DB01109HeparinCoagulation factor Xtarget
DB01109HeparinP-selectintarget
DB01109HeparinHeparanaseenzyme
DB01109HeparinFibroblast growth factor receptor 4target
DB01109HeparinFibroblast growth factor 4target
DB01109HeparinFibroblast growth factor 19target
DB01109HeparinFibroblast growth factor receptor 1target
DB01109HeparinFibroblast growth factor 1target
DB01109HeparinFibroblast growth factor receptor 2target
DB01109HeparinFibroblast growth factor 2target
DB01109HeparinPlatelet factor 4target
DB01109HeparinHepatocyte growth factortarget
DB01109HeparinThyroxine-binding globulincarrier
DB08813NadroparinProto-oncogene c-Fostarget
DB08813NadroparinMyc proto-oncogene proteintarget
DB08813NadroparinP-selectintarget
DB08813NadroparinAntithrombin-IIItarget
DB00775TirofibanIntegrin alpha-IIbtarget
DB00775TirofibanIntegrin beta-3target
DB00661VerapamilSodium channel protein type 5 subunit alphatarget
DB00661VerapamilATP-sensitive inward rectifier potassium channel 11target
DB00661VerapamilVoltage-dependent L-type calcium channel subunit beta-4target
DB00661VerapamilVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00661VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB00661VerapamilVoltage-dependent L-type calcium channel subunit beta-3target
DB00661VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00661VerapamilVoltage-dependent L-type calcium channel subunit beta-1target
DB00661VerapamilVoltage-dependent L-type calcium channel subunit beta-2target
DB00661VerapamilPotassium voltage-gated channel subfamily H member 2target
DB00661VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00661VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00661VerapamilVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB00661VerapamilCytochrome P450 1A2enzyme
DB00661VerapamilCytochrome P450 3A5enzyme
DB00661VerapamilVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB00661VerapamilVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
DB00661VerapamilSodium-dependent serotonin transportertarget
DB00661VerapamilCytochrome P450 3A4enzyme
DB00661VerapamilP-glycoprotein 1transporter
DB00661VerapamilSolute carrier family 22 member 1transporter
DB00661VerapamilCanalicular multispecific organic anion transporter 2transporter
DB00661VerapamilMultidrug resistance-associated protein 4transporter
DB00661VerapamilSolute carrier family 22 member 5transporter
DB00661VerapamilMultidrug resistance-associated protein 1transporter
DB00661VerapamilSolute carrier organic anion transporter family member 1A2transporter
DB00661VerapamilMultidrug resistance-associated protein 7transporter
DB00661VerapamilCanalicular multispecific organic anion transporter 1transporter
DB00661VerapamilSolute carrier family 22 member 4transporter
DB00661VerapamilATP-binding cassette sub-family G member 2transporter
DB00661VerapamilSolute carrier organic anion transporter family member 1B1transporter
DB00661VerapamilCytochrome P450 2C8enzyme
DB00661VerapamilCytochrome P450 2C9enzyme
DB00661VerapamilCytochrome P450 2B6enzyme
DB00661VerapamilCytochrome P450 2C19enzyme
DB00661VerapamilCytochrome P450 2D6enzyme
DB00661VerapamilAlpha-1A adrenergic receptortarget
DB00661VerapamilAlpha-1B adrenergic receptortarget
DB00661VerapamilAlpha-1D adrenergic receptortarget
DB00661VerapamilBile salt export pumptransporter
DrugDrug NamePhaseStatusCount
DB00054Abciximab2Completed1
DB00278Argatroban2Completed1
DB01076Atorvastatin2Unknown Status1
DB12795CMX-20432Completed1
DB06081Caplacizumab2Completed1
DB00758Clopidogrel2Completed1
DB00063Eptifibatide2Completed2
DB04945Hemoglobin2Completed1
DB01109Heparin2Completed1
DB09106Hydroxyethyl Starch2Completed1
DB00133Serine2Terminated1
DB08816Ticagrelor2Completed1
DB00775Tirofiban2Completed1
DB00054Abciximab3Completed2
DB00945Acetylsalicylic acid3Completed1
DB00006Bivalirudin3Completed1
DB00758Clopidogrel3Completed2
DB00758Clopidogrel3Unknown Status1
DB01225Enoxaparin3Completed1
DB01225Enoxaparin3Terminated1
DB00783Estradiol3Completed1
DB11133Omega-3 fatty acids3Completed1
DB09140Oxygen3Completed2
DB14500Potassium3Completed1
DB06209Prasugrel3Completed1
DB00396Progesterone3Completed1
DB06228Rivaroxaban3Completed1
DB01104Sertraline3Completed1
DB00775Tirofiban3Withdrawn1
DB09069Trimetazidine3Recruiting1
DB00163Vitamin E3Completed1
DB00054Abciximab4Completed1
DB00945Acetylsalicylic acid4Recruiting2
DB01076Atorvastatin4Completed2
DB01076Atorvastatin4Unknown Status1
DB01156Bupropion4Completed1
DB06441Cangrelor4Completed1
DB00758Clopidogrel4Active Not Recruiting1
DB00758Clopidogrel4Recruiting1
DB00758Clopidogrel4Unknown Status1
DB00758Clopidogrel4Withdrawn1
DB14726Dabigatran4Withdrawn1
DB06695Dabigatran etexilate4Withdrawn1
DB06779Dalteparin4Terminated1
DB01225Enoxaparin4Recruiting1
DB01225Enoxaparin4Terminated1
DB01095Fluvastatin4Completed1
DB01109Heparin4Terminated1
DB01109Heparin4Unknown Status1
DB01611Hydroxychloroquine4Recruiting1
DB00331Metformin4Recruiting1
DB01233Metoclopramide4Completed1
DB00295Morphine4Completed2
DB01183Naloxone4Completed1
DB09220Nicorandil4Unknown Status1
DB00946Phenprocoumon4Withdrawn1
DB09528Phylloquinone4Withdrawn1
DB06209Prasugrel4Active Not Recruiting1
DB06209Prasugrel4Recruiting1
DB06209Prasugrel4Unknown Status1
DB00175Pravastatin4Completed1
DB06228Rivaroxaban4Recruiting1
DB06228Rivaroxaban4Withdrawn1
DB00641Simvastatin4Completed1
DB01261Sitagliptin4Completed1
DB09153Sodium chloride4Recruiting1
DB08816Ticagrelor4Active Not Recruiting1
DB08816Ticagrelor4Completed4
DB08816Ticagrelor4Recruiting2
DB08816Ticagrelor4Unknown Status2
DB00945Acetylsalicylic acidNot AvailableNot Yet Recruiting1
DB00945Acetylsalicylic acidNot AvailableWithdrawn1
DB00009AlteplaseNot AvailableWithdrawn1
DB00758ClopidogrelNot AvailableWithdrawn1
DB00633DexmedetomidineNot AvailableCompleted1
DB01225EnoxaparinNot AvailableWithdrawn1
DB00281LidocaineNot AvailableCompleted1
DB00086StreptokinaseNot AvailableWithdrawn1