Hypermenorrhea

Also known as: Menorrhagia / Heavy periods NOS / Menstrual flow excessive / Hypermenorrhoea / Heavy periods / Excessive menstruation / Bleeding menstrual heavy / Menses regular with excessive bleeding / Prolonged heavy periods / Menstruation increased

DrugDrug NameDrug Description
DB09123DienogestAn oral progestin used for the treatment of endometriosis as monotherapy or contraception in combination with ethinylestradiol.
DB01395DrospirenoneA progestin used in oral contraceptive pills for the prevention of pregnancy and other conditions.
DB00977EthinylestradiolAn estradiol used as a contraceptive.
DB00823Ethynodiol diacetateAn oral contraceptive used to prevent pregnancy.
DB00367LevonorgestrelA progestin found in oral and IUD contraceptives and at higher doses in emergency contraceptives.
DB00939Meclofenamic acidAn NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis.
DB01357MestranolA synthetic estradiol found in oral contraceptive pills for contraception and the treatment of other conditions in the female reproductive system, such as dysmenorrhea and dysfunctional uterine bleeding.
DB00957NorgestimateA progesterone used as a contraceptive and to treat acne vulgaris.
DB09389NorgestrelA progestin used in combination with ethinyl estradiol for oral contraception and prevention of pregnancy in women.
DrugDrug NameTargetType
DB09123DienogestCytochrome P450 3A4enzyme
DB09123DienogestProgesterone receptortarget
DB09123DienogestAndrogen receptortarget
DB01395DrospirenoneProgesterone receptortarget
DB01395DrospirenoneMineralocorticoid receptortarget
DB01395DrospirenoneAndrogen receptortarget
DB01395DrospirenoneProstaglandin G/H synthase 2enzyme
DB01395DrospirenoneSerum paraoxonase/arylesterase 1enzyme
DB01395DrospirenoneGlucocorticoid receptortarget
DB01395DrospirenoneCytochrome P450 3A4enzyme
DB00977EthinylestradiolEstrogen receptor alphatarget
DB00977EthinylestradiolNuclear receptor subfamily 1 group I member 2target
DB00977EthinylestradiolCytochrome P450 3A4enzyme
DB00977EthinylestradiolCytochrome P450 2C8enzyme
DB00977EthinylestradiolBile salt export pumptransporter
DB00977EthinylestradiolSodium/bile acid cotransportertransporter
DB00977EthinylestradiolCanalicular multispecific organic anion transporter 1transporter
DB00977EthinylestradiolP-glycoprotein 1transporter
DB00977EthinylestradiolSex hormone-binding globulintarget
DB00977EthinylestradiolUDP-glucuronosyltransferase 1-1enzyme
DB00977EthinylestradiolCytochrome P450 2C19enzyme
DB00823Ethynodiol diacetateEstrogen receptor alphatarget
DB00823Ethynodiol diacetateProgesterone receptortarget
DB00823Ethynodiol diacetateCytochrome P450 3A4enzyme
DB00367LevonorgestrelProgesterone receptortarget
DB00367LevonorgestrelEstrogen receptor alphatarget
DB00367Levonorgestrel3-oxo-5-alpha-steroid 4-dehydrogenase 1target
DB00367LevonorgestrelCytochrome P450 3A4enzyme
DB00367LevonorgestrelAndrogen receptortarget
DB00367LevonorgestrelSex hormone-binding globulintarget
DB00367LevonorgestrelGlucocorticoid receptortarget
DB00367LevonorgestrelCytochrome P450 3A5enzyme
DB00939Meclofenamic acidProstaglandin G/H synthase 1target
DB00939Meclofenamic acidProstaglandin G/H synthase 2target
DB00939Meclofenamic acidArachidonate 5-lipoxygenasetarget
DB00939Meclofenamic acidSolute carrier family 22 member 6transporter
DB00939Meclofenamic acidSolute carrier organic anion transporter family member 1C1transporter
DB00939Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 2target
DB00939Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 3target
DB00939Meclofenamic acidThyroxine-binding globulincarrier
DB01357MestranolEstrogen receptor alphatarget
DB01357MestranolCytochrome P450 2C9enzyme
DB01357MestranolCytochrome P450 3A4enzyme
DB01357MestranolCytochrome P450 2C8enzyme
DB00957NorgestimateProgesterone receptortarget
DB00957NorgestimateEstrogen receptor alphatarget
DB00957NorgestimateCanalicular multispecific organic anion transporter 1transporter
DB00957NorgestimateCytochrome P450 3A4enzyme
DB00957NorgestimateAndrogen receptortarget
DB09389NorgestrelProgesterone receptortarget
DB09389Norgestrel3-oxo-5-alpha-steroid 4-dehydrogenase 1target
DB09389NorgestrelAndrogen receptortarget
DB09389NorgestrelCytochrome P450 3A4enzyme
DB09389NorgestrelCytochrome P450 19A1enzyme
DrugDrug NamePhaseStatusCount
DB08995Diosmin1 / 2Recruiting1
DB00302Tranexamic acid1 / 2Recruiting1
DB06680Asoprisnil2Completed1
DB06680Asoprisnil3Completed6
DB13529Dobesilic acid3Recruiting1
DB00367Levonorgestrel3Completed2
DB00367Levonorgestrel3Recruiting1
DB00603Medroxyprogesterone acetate3Completed1
DB00603Medroxyprogesterone acetate3Recruiting1
DB00929Misoprostol3Withdrawn1
DB00302Tranexamic acid3Completed4
DB00302Tranexamic acid3Recruiting1
DB04928XP12B3Completed4
DB00783Estradiol4Completed1
DB00977Ethinylestradiol4Completed1
DB00367Levonorgestrel4Completed2
DB00367Levonorgestrel4Recruiting1
DB00929Misoprostol4Completed1
DB00788Naproxen4Completed2
DB00717Norethisterone4Unknown Status1
DB00675Tamoxifen4Completed1
DB00302Tranexamic acid4Completed2
DB00302Tranexamic acid4Recruiting1
DB00035DesmopressinNot AvailableCompleted1
DB09123DienogestNot AvailableRecruiting1
DB13956Estradiol valerateNot AvailableRecruiting1
DB00977EthinylestradiolNot AvailableCompleted1
DB00294EtonogestrelNot AvailableCompleted1
DB00367LevonorgestrelNot AvailableCompleted3
DB00367LevonorgestrelNot AvailableRecruiting1
DB00603Medroxyprogesterone acetateNot AvailableCompleted1
DB00603Medroxyprogesterone acetateNot AvailableRecruiting1
DB00717NorethisteroneNot AvailableCompleted1
DB00302Tranexamic acidNot AvailableCompleted2