Organic nitrogenous bases. Many alkaloids of medical importance occur in the animal and vegetable kingdoms, and some have been synthesized. (Grant & Hackh's Chemical Dictionary, 5th ed)
DrugDrug NameDrug Description
DB00184NicotineA stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation.
DB00201CaffeineA stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth.
DB00206ReserpineFoe the treatment of hypertension
DB00209TrospiumAn antimuscarinic agent used to treat the symptoms of overactive bladder (OAB).
DB00245BenzatropineAn anticholinergic drug used to treat Parkinson's disease (PD) and extrapyramidal symptoms, except tardive dyskinesia.
DB00247MethysergideAn ergot alkaloid used for the prophylaxis of migraine and cluster headaches.
DB00248CabergolineA dopamine receptor agonist used for the treatment of hyperprolactinemic conditions due to various causes.
DB00277TheophyllineA xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction.
DB00295MorphineAn opioid agonist used for the relief of moderate to severe acute and chronic pain.
DB00309VindesineA vinca alkaloid derived from vinblastine used for various types of malignancies, but mainly acute lymphocytic leukemia (ALL).
DB00318CodeineAn opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated.
DB00320DihydroergotamineAn ergot alkaloid used in the acute treatment of migraine headache and cluster headache.
DB00327HydromorphoneAn opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated.
DB00332IpratropiumAn anticholinergic drug used in the control of symptoms related to bronchospasm in chronic obstructive pulmonary disease (COPD).
DB00353MethylergometrineAn ergot alkaloid used to prevent and control uterine atony and hemorrhage before and after delivery.
DB00361VinorelbineA vinca alkaloid used in the treatment of metastatic non-small cell lung carcinoma (NSLC) and in conjunction with other drugs in locally advanced NSCLC.
DB00416Metocurine iodideFor use as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy.
DB00419MiglustatA glucosylceramide synthase inhibitor used for the management of mild to moderate type I Gaucher disease for patients who are not candidates for whole enzyme replacement.
DB00424HyoscyamineFor treatment of bladder spasms, peptic ulcer disease, diverticulitis, colic, irritable bowel syndrome, cystitis, and pancreatitis. Also used to treat certain heart conditions, to control the symptoms of Parkinson's disease...
DB00468QuinineAn alkaloid used to treat uncomplicated Plasmodium falciparum malaria.
DB00491MiglitolAn oral alpha-glucosidase inhibitor used to improve glycemic control by delaying the digestion of carbohydrates.
DB00497OxycodoneAn opioid used in the management of moderate to severe pain.
DB00504LevallorphanFor the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids.
DB00514DextromethorphanAn NMDA receptor antagonist used to treat cases of dry cough.
DB00517Anisotropine methylbromideFor use in conjunction with antacids or histamine H2-receptor antagonists in the treatment of peptic ulcer, to reduce further gastric acid secretion and delay gastric emptying.
DB00541VincristineA vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis.
DB00565CisatracuriumA skeletal muscle relaxant used to facilitate tracheal intubation, muscle relaxation in surgery, or mechanical ventilation.
DB00570VinblastineA vinca alkaloid used to treat breast cancer, testicular cancer, neuroblastoma, Hodgkin's and non-Hodgkins lymphoma, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.
DB00572AtropineA muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs.
DB00589LisurideFor the management of Parkinson's Disease
DB00611ButorphanolAn opioid agonist-antagonist used to treat moderate to severe pain.
DB00651DyphyllineA theophylline derivative used to treat asthma, bronchospasm, and COPD.
DB00652PentazocineAn analgesic used to treat moderate to severe pain.
DB00674GalantamineA benzazepine derivative used to treat mild to moderate dementia associated with Alzheimer's Disease.
DB00696ErgotamineA alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches.
DB00699NicergolineFor the treatment of senile dementia, migraines of vascular origin, transient ischemia, platelet hyper-aggregability, and macular degeneration.
DB00704NaltrexoneA narcotic antagonist used in opioid overdose.
DB00714ApomorphineA morphine derivative D2 dopamine agonist used to treat hypomobile "off" episodes of advanced Parkinson's disease.
DB00725Homatropine methylbromideA muscarinic receptor antagonist used to treat peptic ulcers, gastric ulcers, and duodenal ulcers.
DB00732Atracurium besylateA non-depolarizing neuromuscular blocker used to facilitate endotracheal intubation and relax skeletal muscles during surgery.
DB00747ScopolamineAn anticholinergic used to treat excessive salivation, colicky abdominal pain, bradycardia, diverticulitis, IBS, and motion sickness.
DB00762IrinotecanAn antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum.
DB00785CryptenamineFor the treatment of hypertension.
DB00806PentoxifyllineA methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs.
DB00824EnprofyllineUsed in the management of symptoms of asthma. Also used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.
DB00844NalbuphineAn opioid agonist-antagonist used to treat pain, for pre and postoperative analgesia, and for analgesia in labor and delivery.
DB00854LevorphanolAn opioid analgesic used to treat moderate to severe pain.
DB00907CocaineAn ester local anesthetic used during diagnostic procedures and surgeries in or through the nasal cavities.
DB00908QuinidineA medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
DB00921BuprenorphineA partial opioid agonist used for management of severe pain that is not responsive to alternative treatments. Also used for maintenance treatment of opioid addiction.
DB00956HydrocodoneAn opioid agonist used as an analgesic and antitussive agent.
DB00981PhysostigmineA cholinesterase inhibitor used to treat glaucoma and anticholinergic toxicity.
DB00985DimenhydrinateA medication used to prevent and treat nausea, vomiting, vertigo, and motion sickness.
DB01030TopotecanAn antineoplastic agent used to treat ovarian cancer, small cell lung cancer, or cervical cancer.
DB01049Ergoloid mesylateA nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity.
DB01085PilocarpineA muscarinic cholinergic agonist used on the eye to treat elevated intraocular pressure, various types of glaucoma, and to induce miosis. Also available orally to treat symptoms of dry mouth associated with Sjogren's syndrome and radiotherapy.
DB01089DeserpidineAn alkaloid that has been used to manage hypertension.
DB01113PapaverineAn alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms".
DB01180RescinnamineFor the treatment of hypertension.
DB01183NaloxoneAn opioid receptor antagonist used to rapidly reverse an opioid overdose. Also included in some drug formulations as an abuse deterrent to prevent injection.
DB01186PergolideA long-acting dopamine agonist that is uncommonly used for the management of Parkinson's disease, due to the risk for cardiac valvulopathy.
DB01192OxymorphoneAn opioid analgesic used in the management of moderate-to-severe pain and for analgesic therapies.
DB01199TubocurarineA neuromuscular blocker used for the diagnosis of and facilitation of intubation after induction of anesthesia during surgical procedures.
DB01200BromocriptineA dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome.
DB01223AminophyllineA bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.
DB01253ErgometrineAn ergot alkaloid used for the treatment of postpartum haemorrhage and post abortion hemorrhage in patients with uterine atony.
DB01303OxtriphyllineA bronchodilator used for the treatment of asthma, bronchitis, COPD, and emphysema.
DB01336MetocurineMetocurine is a muscle relaxant.
DB01392YohimbineAn alpha-2-adrenergic blocker and sympatholytic found in supplements used to.
DB01394ColchicineAn alkaloid used in the symptomatic relief of pain in attacks of gout and to treat the inflammatory symptoms of Familial Mediterranean Fever (FMF).
DB01409TiotropiumA long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD).
DB01412Theobrominetheobromine is used as a vasodilator, a diuretic, and heart stimulant. And similar to caffeine, it may be useful in management of fatigue and orthostatic hypotension.
DB01426AjmalineFor use as an antiarrhythmic agent.
DB014415-Methoxy-N,N-diisopropyltryptamine5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) is a tryptamine derivative and shares many similarities with schedule I tryptamine hallucinogens such as alpha-ethyltryptamine, N,N-dimethyltryptamine, N,N-diethyltryptamine, bufotenine, psilocybin and psilocin. Since 1999, there has been a...
DB01450DihydroetorphineNot Available
DB01452DiamorphineAn opioid analgesic agent used in the relief of severe pain associated with surgical procedures, myocardial infarction or pain in the terminally ill and for the relief of dyspnea in acute pulmonary edema.
DB01466EthylmorphineEthylmorphine is an analgesic used for pain relief.
DB01480CyprenorphineNot Available
DB01482FenethyllineNot Available
DB01497EtorphineEtorphine is only available for its use in veterinary. This main usage is related to the immobilization of large mammals.
DB01515BenzoylecgonineBenzoylecgonine is the major metabolite of cocaine. It is formed by hydrolysis of cocaine in the liver, catalysed by carboxylesterases. It is excreted in the urine of cocaine users after...
DB01525EcgonineNot Available
DB01531DesomorphineNot Available
DB01547DrotebanolNot Available
DB01548DiprenorphineDiprenorphine is indicated to reverse the effects of powerful opioids including etorphine and carfentanil, often used for tranquilizing large animals. This drug is not approved for use in humans.
DB01551DihydrocodeineAn opioid analgesic agent used for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.
DB01565DihydromorphineDihydromorphine is an opioid analgesic used for moderate to severe pain relief.
DB01874TropinoneNot Available
DB018758-AzaxanthineNot Available
DB019337-HydroxystaurosporineNot Available
DB02010StaurosporineAn indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)
DB02134XanthineA purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is an intermediate in the degradation of adenosine monophosphate to uric acid, being...
DB02152K-252aNot Available
DB03206DuvoglustatAn alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
DB04026PseudotropineNot Available
DB04115BerberineAn alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal...
DB04365ArecolineAn alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the...
DB04688MethylecgonineNot Available
DB04690CamptothecinInvestigated for the treatment of cancer.
DB04829Lysergic acid diethylamideDebate continues over the nature and causes of chronic flashbacks. Explanations in terms of LSD physically remaining in the body for months or years after consumption have been discounted by...
DB04865Omacetaxine mepesuccinateA cephalotaxine used in the treatment of Chronic Myeloid Leukemia (CML) that is intolerant to or resistant to two or more tyrosine kinase inhibitors.
DB04877VoacamineFor the treatment of malaria. Also under investigation for the modulation of multidrug resistance in cancer cells.
DB04892PhenserineFor the treatment of Alzheimer's disease (AD).
DB04947AltropaneInvestigated for use/treatment in attention deficit/hyperactivity disorder (ADHD), parkinson's disease, and pediatric indications.
DB05018MigalastatAn alpha-galactosidase A chaperone used for the treatment of Fabry disease in patients with an amenable galactosidase alpha gene (GLA) variant.
DB05137LobelineInvestigated for use/treatment in addictions.
DB05168VintafolideInvestigated for use/treatment in solid tumors.
DB05805NS-2359Investigated for use/treatment in addictions, attention deficit/hyperactivity disorder (ADHD), and depression.
DB05806CositecanInvestigated for use/treatment in brain cancer, lung cancer, and melanoma.
DB05855RivaniclineInvestigated for use/treatment in ulcerative colitis.
DB05899IT-101Investigated for use/treatment in cancer/tumors (unspecified) and solid tumors.
DB06069XMT-1001Investigated for use/treatment in solid tumors.
DB06159RubitecanInvestigated for use/treatment in pancreatic cancer, leukemia (unspecified), melanoma, ovarian cancer, and cancer/tumors (unspecified).
DB06174NoscapineInvestigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), cancer/tumors (unspecified), and multiple myeloma.
DB06230NalmefeneAn opioid antagonist used in conjunction with psychosocial support to help adults with alcohol dependence reduce alcohol consumption.
DB06471NaxifyllineInvestigated for use/treatment in congestive heart failure.
DB06479PropentofyllineInvestigated for use/treatment in alzheimer's disease.
DB06595MidostaurinAn antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL).
DB06721GimatecanGimatecan is an orally available 7-t-butoxyiminomethyl-substituted lipophilic camptothecin derivative.
DB06727SparteineSparteine is a plant alkaloid derived from Cytisus scoparius and Lupinus mutabilis which may chelate calcium and magnesium. It is a sodium channel blocker so it falls under the category...
DB06751DrotaverineUsed in the treatment of functional bowel disorders and alleviating pain in renal colic.
DB06774CapsaicinA topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain.
DB06800MethylnaltrexoneA ╬╝-opioid antagonist used for the treatment of opioid-induced constipation in palliative patients that are inadequately responding to laxative therapy.
DB079543-isobutyl-1-methyl-7H-xanthineNot Available
DB08824Ioflupane I-123A radiopharmaceutical used in single photon emission computed tomography (SPECT) brain imaging to help diagnose patients with suspected Parkinsonian syndromes.
DB08844Uric acidAt present (August 2013), there is no approved indication for uric acid. The potential therapeutic use for uric acid is as an adjunct in acute ischemic stroke.
DB08897AclidiniumAn inhaled long-acting anticholinergic used as a maintenance bronchodilator in patients with chronic obstructive pulmonary disease (COPD).
DB08978FentoniumFentonium is an atropine derivative.
DB09049NaloxegolA peripherally-selective opioid antagonist used to treat opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain.
DB09092XanthinolA vasodilatory niacin found in diet supplements.
DB09120ZucapsaicinA topical analgesic used as an adjunct to relieve severe pain of osteoarthritis of the knee in selected adult patients.
DB09209PholcodinePholcodine is indicated as a cough suppressant for the temporary relief of non-productive dry cough. It is stated to present a required label indication of "temporary relief of dry cough."...
DB09271CimetropiumCimetropium is a semi-synthetic belladonna alkaloid and derivative of scopolamine. It is a potent antimuscarinic and an effective antispasmodic drug. It is also endowed of a direct myolitic action which...
DB09273DoxofyllineIndicated for the treatment of chronic obstructive pulmonary disease (COPD), bronchial asthma and pulmonary disease with spastic bronchial component.
DB09300ButylscopolamineAn antispasmodic and anticholinergic agent used for the symptomatic treatment of abdominal cramping and pain.
DB11181HomatropineAn anticholinergic agent used to dilate the pupil, treat inflammation of the uveal tract, and suppress a cough.
DB11273DihydroergocornineA nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity.
DB11275EpicriptineA nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity.
DB11315MethscopolamineMethscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The...
DB11324NonivamideNonivamide is used as a topical analgesic and is also used as a flavoring ingredient , , .
DB11490NalorphineUsed to reverse opioid overdose.
DB11562BicucullineBicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and...
DB11582ThiocolchicosideThiocolchicoside is a skeletal muscle-relaxant drug used in the treatment of orthopedic, traumatic and rheumatologic disorders . It is indicated as an adjuvant drug in the treatment of painful muscle...
DB11641VinflunineA vinca alkaloid used to treat advanced or metastatic transitional cell carcinoma of the urothelial tract after a platinum containing treatment has failed.
DB11664PsilocybinePsilocybin has been investigated for the treatment of Anxiety and Stage IV Melanoma.
DB11785AnisodamineAnisodamine has been investigated for the treatment of Intestinal Diseases.
DB12013AxelopranAxelopran has been used in trials studying the treatment of OIC and Opioid-induced Constipation.
DB12086OxitropiumOxitropium has been investigated for the treatment of Pulmonary Disease, Chronic Obstructive.
DB12093TetrahydropalmatineTetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity).
DB12124NamitecanNamitecan has been used in trials studying the treatment of Solid Tumors.
DB12131VinpocetineVinpocetine has been investigated for the treatment of Epilepsy.
DB12185ExatecanExatecan has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Lung Cancer, and Liver Cancer, among others.
DB12222LurtotecanLurtotecan is under investigation in clinical trial NCT00022594 (Liposomal Lurtotecan in Treating Patients With Metastatic or Locally Recurrent Head and Neck Cancer).
DB12251MoxaverineMoxaverine has been investigated for the treatment of Retina, Ocular Physiology, and Regional Blood Flow.
DB12384AR-67AR-67 has been used in trials studying the treatment of GBM, Tumors, Gliosarcoma, Solid Malignancies, and Glioblastoma Multiforme, among others.
DB1238510-hydroxycamptothecin10-hydroxycamptothecin is under investigation in clinical trial NCT00956787 (Study of AR-67 (DB-67) in Myelodysplastic Syndrome (MDS)).
DB12406LisofyllineLisofylline has been investigated for the treatment of Type 1 Diabetes Mellitus.
DB12454ZalypsisZalypsis has been used in trials studying the treatment of Lymphoma, Solid Tumors, Ewing's Sarcoma, Endometrial Cancer, and Uterine Cervical Cancer, among others.
DB12459BelotecanBelotecan has been investigated for the treatment of Epithelial Ovarian Cancer.
DB125159-aminocamptothecinAminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian Cancer, Esophageal Cancer, and Ovarian Neoplasms, among others.
DB12543SamidorphanSamidorphan has been used in trials studying the treatment of Schizophrenia, Alcohol Dependence, and Binge Eating Disorder.
DB12569TonapofyllineTonapofylline has been used in trials studying the treatment of Heart Failure, Renal Insufficiency, and Congestive Heart Failure.
DB12655PatidegibPatidegib has been investigated for the treatment of Conventional Chondrosarcoma.
DB12670RolofyllineRolofylline is under clinical development by pharmaceutical company NovaCardia for the treatment of congestive heart failure.
DB12700SolamargineSolamargine has been used in trials studying the treatment of Actinic Keratosis.
DB12842PegamotecanPegamotecan has been used in trials studying the treatment of Cancer of Stomach, Sarcoma, Soft Tissue, and Gastroesophageal Cancer.
DB12846ReproterolReproterol has been used in trials studying the treatment of Asthma, Exercise-Induced.
DB12893Sacituzumab govitecanSacituzumab govitecan has been used in trials studying the treatment of Breast Cancer, Cervical Cancer, Renal Cell Cancer, Colorectal Cancer, and Esophageal Cancer, among others.
DB12926CafedrineCafedrine is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
DB12927TheodrenalineTheodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
DB129468-cyclopentyl-1,3-dipropylxanthineCPX has been used in trials studying the treatment of Cystic Fibrosis.
DB13098CT-2584CT-2584 has been used in trials studying the treatment of Prostate Cancer.
DB13141Ambroxol acefyllinateNot Annotated
DB13203BamifyllineBamifylline is a selective A1 adenosine receptor antagonist.
DB13295AtracuriumNot Annotated
DB13318DemecolcineNot Annotated
DB13345DihydroergocristineAn ergot alkaloid used to delay progressive mental decline in conditions like Alzheimer's.
DB13374VincamineVincamine is a monoterpenoid indole alkaloid obtained from the leaves of Vinca minor with a vasodilatory property. Studies indicate that vincamine increases the regional cerebral blood flow.
DB13385DihydroergocryptineNot Annotated
DB13393EmetineNot Annotated
DB13399TergurideNot Annotated
DB13449ProxyphyllineNot Annotated
DB13454NicomorphineNot Annotated
DB13468EtybenzatropineNot Annotated
DB13471NalfurafineNot Annotated
DB13520MetergolineMetergoline is an ergot-derived psychoactive drug that acts as a ligand for serotonin and dopamine receptors. Metergoline is an antagonist at various 5-HT receptor subtypes at a relatively low concentration...
DB13555PrajmalineNot Annotated
DB13573AcefyllineNot Annotated
DB13575BietaserpineNot Annotated
DB13592EtamiphyllineNot Annotated
DB13606PhenazocineNot Annotated
DB13634PentifyllineNot Annotated
DB13648AlcuroniumA non-depolarizing skeletal muscle relaxant similar to tubocurarine. It is used as an anesthesia adjuvant.
DB13651LorajmineNot Annotated
DB13692TretoquinolNot Annotated
DB13718HydroquinineNot Annotated
DB13793VinburnineNot Annotated
DB13810DimemorfanNot Annotated
DB13812BufyllineNot Annotated
DB13833MethylatropineNot Annotated
DB13865DehydroemetineNot Annotated
DB13875HarmalineNot Annotated
DB14018BromotheophyllineBromotheophylline is used as a diuretic and also, in combination with DB00316, it is used for the relief of temporary water weight gain, bloating, swelling and full feeling associated with...
DB14029FurafyllineFurafylline is a derivative of methylxanthine derivative. It was developed on the context of asthma as a long-acting alternative for theophylline.
DB14066TetrandrineNot Annotated
DB141328-chlorotheophyllineWhen used in combination with DB01075 as the antiemetic DB00985, 8-chlorotheophylline is indicated for the prevention and treatment of nausea, vomiting, or vertigo of motion sickness.
DB14682DextrorphanNot Annotated
DB054827-ethyl-10-hydroxycamptothecinInvestigated for use/treatment in colorectal cancer.
DB09363Rauwolfia serpentina rootRauwolfia alkaloids are indicated in the treatment of hypertension . Rauwolfia alkaloids have been used for relief of symptoms in agitated psychotic states such as schizophrenia; however, use as antipsychotics...
DB01430AlmitrineFor the treatment of chronic obstructive pulmonary disease.
DB06409Morphine glucuronideInvestigated for use/treatment in pain (acute or chronic).
DB14953Firtecan pegolFirtecan pegol is under investigation in clinical trial NCT01036113 (A Phase 2 Study of EZN-2208 in Patients With Metastatic Breast Cancer).
DB1509618-methoxycoronaridine18-methoxycoronaridine is under investigation in clinical trial NCT03084952 (Phase 2 Trial to Evaluate 18-Methoxycoronaridine Efficacy, Safety and Tolerability in Cutaneous Leishmaniasis Patients).
DB15300HydroquinidineHydroquinidine is under investigation in clinical trial NCT00927732 (Hydroquinidine Versus Placebo in Patients With Brugada Syndrome).
DB15317PosiphenPosiphen is under investigation in clinical trial NCT02925650 (Safety, Tolerability, PK and PD of Posiphen® in Subjects With Early Alzheimer's Disease).
DB15398DihydrocapsiateDihydrocapsiate is under investigation in clinical trial NCT00999297 (Effect of 4-week Dihydrocapsiate Ingestion on Resting Metabolic Rate).
DB11691NaldemedineAn opioid antagonist used to to treat opioid-induced constipation.
DB13466DeptropineNot Annotated
DB13481TenidapNot Annotated
DB14146LoxicodegolLoxicodegol was developed as an opioid analgesic with low abuse potential for use in treating chronic pain . An application has been filed for FDA approval of Loxicodegol for use...
DB14872LucerastatLucerastat is under investigation in clinical trial NCT03425539 (Efficacy and Safety of Lucerastat Oral Monotherapy in Adult Subjects With Fabry Disease).
DB14962Trastuzumab deruxtecanTrastuzumab deruxtecan is under investigation in clinical trial NCT02564900 (Study of DS-8201a in Subjects With Advanced Solid Malignant Tumors).
DB15122PCS-499PCS-499 is under investigation in clinical trial NCT01487109 (A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-499 in Type 2 Diabetic Nephropathy Patients).
DB15534ColchiceineNot Annotated
DrugDrug NameTargetType
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-2target
DB00184NicotineNeuronal acetylcholine receptor subunit beta-2target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-7target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-4target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-10target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-9target
DB00184NicotineCytochrome P450 2A6enzyme
DB00184NicotineCytochrome P450 2E1enzyme
DB00184NicotineCytochrome P450 2A13enzyme
DB00184NicotineCytochrome P450 2B6enzyme
DB00184NicotineNeuronal acetylcholine receptor subunit beta-4target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-3target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-5target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-6target
DB00184NicotineNeuronal acetylcholine receptor subunit beta-3target
DB00184NicotineSolute carrier family 22 member 2transporter
DB00184NicotineSolute carrier family 22 member 1transporter
DB00184NicotineSolute carrier family 22 member 3transporter
DB00184NicotineSolute carrier family 22 member 5transporter
DB00184NicotineSolute carrier family 22 member 4transporter
DB00184NicotineCytochrome P450 1A1enzyme
DB00184NicotineCytochrome P450 1A2enzyme
DB00184NicotineCytochrome P450 2C19enzyme
DB00184NicotineCytochrome P450 2C8enzyme
DB00184NicotineCytochrome P450 2C9enzyme
DB00184NicotineCytochrome P450 2D6enzyme
DB00184NicotineCytochrome P450 3A4enzyme
DB00184NicotineAmine oxidase [flavin-containing] Aenzyme
DB00184NicotineAmine oxidase [flavin-containing] Benzyme
DB00184NicotineCytochrome P450 19A1target
DB00184NicotineCholine O-acetyltransferasetarget
DB00201CaffeineAdenosine receptor A1target
DB00201CaffeinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB00201CaffeineAdenosine receptor A2atarget
DB00201CaffeineCytochrome P450 1A2enzyme
DB00201CaffeineRyanodine receptor 1target
DB00201CaffeineCytochrome P450 3A4enzyme
DB00201CaffeineCytochrome P450 2E1enzyme
DB00201CaffeineCytochrome P450 2C8enzyme
DB00201CaffeineCytochrome P450 2C9enzyme
DB00201CaffeineCytochrome P450 1A1enzyme
DB00201CaffeineCytochrome P450 1B1enzyme
DB00201CaffeineCytochrome P450 2D6enzyme
DB00201CaffeineCyclic nucleotide phosphodiesterasetarget
DB00201CaffeineDNA-dependent protein kinase catalytic subunittarget
DB00201CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
DB00201CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
DB00201CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformtarget
DB00201CaffeineInositol 1,4,5-trisphosphate receptortarget
DB00201CaffeineSerine-protein kinase ATMtarget
DB00201CaffeineATP-binding cassette sub-family G member 2transporter
DB00201CaffeineAdenosine receptor A2btarget
DB00201CaffeineAdenosine receptor A3target
DB00201CaffeinePhosphodiesterase enzymestarget
DB00206ReserpineSynaptic vesicular amine transportertarget
DB00206ReserpineP-glycoprotein 1transporter
DB00206ReserpineSolute carrier family 22 member 1transporter
DB00206ReserpineBile salt export pumptransporter
DB00206ReserpineCanalicular multispecific organic anion transporter 1transporter
DB00206ReserpineSolute carrier family 22 member 2transporter
DB00206ReserpineCytochrome P450 3A5enzyme
DB00206ReserpineChromaffin granule amine transportertarget
DB00206ReserpineBaculoviral IAP repeat-containing protein 5target
DB00206ReserpineSolute carrier organic anion transporter family member 1B1transporter
DB00206ReserpineSolute carrier organic anion transporter family member 2B1transporter
DB00209TrospiumMuscarinic acetylcholine receptor M1target
DB00209TrospiumCytochrome P450 2D6enzyme
DB00245BenzatropineMuscarinic acetylcholine receptor M1target
DB00245BenzatropineSodium-dependent dopamine transportertarget
DB00245BenzatropineHistamine H1 receptortarget
DB00245BenzatropineSerum albumincarrier
DB00245BenzatropineSodium-dependent serotonin transportertarget
DB00245BenzatropineSodium-dependent noradrenaline transportertarget
DB00247Methysergide5-hydroxytryptamine receptor 2Atarget
DB00247Methysergide5-hydroxytryptamine receptor 1Atarget
DB00247Methysergide5-hydroxytryptamine receptor 7target
DB00247Methysergide5-hydroxytryptamine receptor 2Ctarget
DB00247Methysergide5-hydroxytryptamine receptor 2Btarget
DB00247Methysergide5-hydroxytryptamine receptor 1Btarget
DB00247Methysergide5-hydroxytryptamine receptor 1Ftarget
DB00247Methysergide5-hydroxytryptamine receptor 1Etarget
DB00247MethysergideCytochrome P450 3A4enzyme
DB00248CabergolineDopamine D2 receptortarget
DB00248Cabergoline5-hydroxytryptamine receptor 2Btarget
DB00248CabergolineDopamine D3 receptortarget
DB00248Cabergoline5-hydroxytryptamine receptor 2Atarget
DB00248CabergolineAlpha-2B adrenergic receptortarget
DB00248Cabergoline5-hydroxytryptamine receptor 1Dtarget
DB00248CabergolineDopamine D4 receptortarget
DB00248CabergolineAlpha-2A adrenergic receptortarget
DB00248Cabergoline5-hydroxytryptamine receptor 1Atarget
DB00248CabergolineAlpha-2C adrenergic receptortarget
DB00248CabergolineDopamine D5 receptortarget
DB00248CabergolineDopamine D1 receptortarget
DB00248Cabergoline5-hydroxytryptamine receptor 1Btarget
DB00248Cabergoline5-hydroxytryptamine receptor 2Ctarget
DB00248CabergolineCytochrome P450 3A4enzyme
DB00248Cabergoline5-hydroxytryptamine receptor 7target
DB00248CabergolineAlpha-1A adrenergic receptortarget
DB00248CabergolineAlpha-1B adrenergic receptortarget
DB00248CabergolineAlpha-1D adrenergic receptortarget
DB00248CabergolineBeta-1 adrenergic receptortarget
DB00248CabergolineBeta-2 adrenergic receptortarget
DB00248CabergolineD(1) dopamine receptortarget
DB00248CabergolineP-glycoprotein 1transporter
DB00277TheophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB00277TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB00277TheophyllineAdenosine receptor A2btarget
DB00277TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB00277TheophyllinecGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00277TheophyllineAdenosine receptor A1target
DB00277TheophyllineAdenosine receptor A2atarget
DB00277TheophyllineCytochrome P450 1A2enzyme
DB00277TheophyllineAdenosine deaminaseenzyme
DB00277TheophyllineCytochrome P450 2E1enzyme
DB00277TheophyllineCytochrome P450 3A4enzyme
DB00277TheophyllineSolute carrier family 22 member 7transporter
DB00277TheophyllineCytochrome P450 1A1enzyme
DB00277TheophyllineCytochrome P450 1B1enzyme
DB00277TheophyllineCytochrome P450 2D6enzyme
DB00277TheophyllineHistone deacetylase 2target
DB00277TheophyllineCopine-1target
DB00277TheophyllineMinor histocompatibility antigen H13target
DB00277TheophyllineNodal modulator 1target
DB00277TheophyllinePoly [ADP-ribose] polymerase 1target
DB00277TheophyllineProtein RIC-3target
DB00277TheophyllineTubulin monoglycylase TTLL3target
DB00295MorphineMu-type opioid receptortarget
DB00295MorphineDelta-type opioid receptortarget
DB00295MorphineKappa-type opioid receptortarget
DB00295MorphineP-glycoprotein 1transporter
DB00295MorphineCytochrome P450 2C8enzyme
DB00295MorphineCytochrome P450 3A4enzyme
DB00295MorphineUDP-glucuronosyltransferase 2B7enzyme
DB00295MorphineUDP-glucuronosyltransferase 1-1enzyme
DB00295MorphineUDP-glucuronosyltransferase 1-8enzyme
DB00295MorphineUDP-glucuronosyltransferase 2B15enzyme
DB00295MorphineUDP-glucuronosyltransferase 2B4enzyme
DB00295MorphineUDP-glucuronosyltransferase 1-3enzyme
DB00295MorphineLymphocyte antigen 96target
DB00295MorphineSerum albumincarrier
DB00309VindesineTubulin beta-1 chaintarget
DB00309VindesineCytochrome P450 3A4enzyme
DB00318CodeineMu-type opioid receptortarget
DB00318CodeineDelta-type opioid receptortarget
DB00318CodeineKappa-type opioid receptortarget
DB00318CodeineCytochrome P450 2D6enzyme
DB00318CodeineCytochrome P450 3A4enzyme
DB00318CodeineSolute carrier family 22 member 1transporter
DB00318CodeineUDP-glucuronosyltransferase 2B7enzyme
DB00318CodeineUDP-glucuronosyltransferase 2B4enzyme
DB00320Dihydroergotamine5-hydroxytryptamine receptor 1Dtarget
DB00320Dihydroergotamine5-hydroxytryptamine receptor 1Btarget
DB00320DihydroergotamineCytochrome P450 3A4enzyme
DB00320DihydroergotamineAlpha-2A adrenergic receptortarget
DB00320Dihydroergotamine5-hydroxytryptamine receptor 2Btarget
DB00320DihydroergotamineP-glycoprotein 1transporter
DB00327HydromorphoneMu-type opioid receptortarget
DB00327HydromorphoneDelta-type opioid receptortarget
DB00327HydromorphoneKappa-type opioid receptortarget
DB00327HydromorphoneCytochrome P450 2C9enzyme
DB00327HydromorphoneUDP-glucuronosyltransferase 1-3enzyme
DB00327HydromorphoneUDP-glucuronosyltransferase 2B7enzyme
DB00327HydromorphoneSerum albumincarrier
DB00332IpratropiumMuscarinic acetylcholine receptor M1target
DB00332IpratropiumMuscarinic acetylcholine receptor M2target
DB00332IpratropiumMuscarinic acetylcholine receptor M3target
DB00332IpratropiumSolute carrier family 22 member 5transporter
DB00332IpratropiumSolute carrier family 22 member 4transporter
DB00332IpratropiumSerum albumincarrier
DB00332Ipratropiumalpha1-acid glycoproteincarrier
DB00353MethylergometrineDopamine D1 receptortarget
DB00353MethylergometrineCytochrome P450 3A4enzyme
DB00353Methylergometrine5-hydroxytryptamine receptor 2Btarget
DB00361VinorelbineTubulin beta chaintarget
DB00361VinorelbineCytochrome P450 3A4enzyme
DB00361VinorelbineP-glycoprotein 1transporter
DB00361VinorelbineCytochrome P450 2D6enzyme
DB00416Metocurine iodideNeuronal acetylcholine receptor subunit alpha-2target
DB00419MiglustatCeramide glucosyltransferasetarget
DB00424HyoscyamineMuscarinic acetylcholine receptor M1target
DB00424HyoscyamineMuscarinic acetylcholine receptor M2target
DB00424HyoscyamineMuscarinic acetylcholine receptor M3target
DB00424HyoscyamineMuscarinic acetylcholine receptor M4target
DB00468QuininePlatelet glycoprotein IXtarget
DB00468QuinineIntermediate conductance calcium-activated potassium channel protein 4target
DB00468QuinineCytochrome P450 3A4enzyme
DB00468QuinineCytochrome P450 3A5enzyme
DB00468QuinineCytochrome P450 1A1enzyme
DB00468QuinineCytochrome P450 2D6enzyme
DB00468QuinineCytochrome P450 1A2enzyme
DB00468QuinineCytochrome P450 2C8enzyme
DB00468QuinineCytochrome P450 2C9enzyme
DB00468QuinineCytochrome P450 2C19enzyme
DB00468QuinineCytochrome P450 2E1enzyme
DB00468QuinineCytochrome P450 3A7enzyme
DB00468QuinineSolute carrier family 22 member 2transporter
DB00468QuinineSolute carrier family 22 member 1transporter
DB00468QuinineSolute carrier family 22 member 5transporter
DB00468QuinineP-glycoprotein 1transporter
DB00468QuinineSolute carrier organic anion transporter family member 1A2transporter
DB00468QuinineSolute carrier family 22 member 4transporter
DB00468QuinineFe(II)-protoporphyrin IXtarget
DB00468QuinineSolute carrier organic anion transporter family member 1B1transporter
DB00491MiglitolMaltase-glucoamylase, intestinaltarget
DB00491MiglitolPancreatic alpha-amylaseenzyme
DB00491MiglitolLysosomal alpha-glucosidasetarget
DB00491MiglitolNeutral alpha-glucosidase ABtarget
DB00491MiglitolNeutral alpha-glucosidase Ctarget
DB00497OxycodoneMu-type opioid receptortarget
DB00497OxycodoneKappa-type opioid receptortarget
DB00497OxycodoneDelta-type opioid receptortarget
DB00497OxycodoneCytochrome P450 2D6enzyme
DB00497OxycodoneCytochrome P450 3A4enzyme
DB00497OxycodoneCytochrome P450 3A5enzyme
DB00497OxycodoneSerum albumincarrier
DB00497Oxycodonealpha1-acid glycoproteincarrier
DB00504LevallorphanMu-type opioid receptortarget
DB00514DextromethorphanSigma non-opioid intracellular receptor 1target
DB00514DextromethorphanHCG20471, isoform CRA_ctarget
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-2target
DB00514DextromethorphanSodium-dependent serotonin transportertarget
DB00514DextromethorphanGlutamate receptor ionotropic, NMDA 3Atarget
DB00514DextromethorphanCytochrome P450 2D6enzyme
DB00514DextromethorphanCytochrome P450 3A4enzyme
DB00514DextromethorphanCytochrome P450 3A7enzyme
DB00514DextromethorphanCytochrome P450 2C9enzyme
DB00514DextromethorphanCytochrome P450 2B6enzyme
DB00514DextromethorphanCytochrome P450 2C19enzyme
DB00514DextromethorphanMembrane-associated progesterone receptor component 1target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-3target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-4target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit beta-4target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit beta-2target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-7target
DB00514DextromethorphanMu-type opioid receptortarget
DB00514DextromethorphanDelta-type opioid receptortarget
DB00514DextromethorphanKappa-type opioid receptortarget
DB00514DextromethorphanNADPH oxidasetarget
DB00514DextromethorphanSodium-dependent noradrenaline transportertarget
DB00517Anisotropine methylbromideMuscarinic acetylcholine receptor M1target
DB00517Anisotropine methylbromideMuscarinic acetylcholine receptor M2target
DB00517Anisotropine methylbromideMuscarinic acetylcholine receptor M3target
DB00541VincristineTubulin beta chaintarget
DB00541VincristineCytochrome P450 3A4enzyme
DB00541VincristineCytochrome P450 3A5enzyme
DB00541VincristineCytochrome P450 3A7enzyme
DB00541VincristineP-glycoprotein 1transporter
DB00541VincristineCanalicular multispecific organic anion transporter 2transporter
DB00541VincristineSolute carrier family 22 member 3transporter
DB00541VincristineMultidrug resistance-associated protein 1transporter
DB00541VincristineMultidrug resistance-associated protein 7transporter
DB00541VincristineCanalicular multispecific organic anion transporter 1transporter
DB00541VincristineBile salt export pumptransporter
DB00541VincristineATP-binding cassette sub-family G member 2transporter
DB00541VincristineTubulin alpha-4A chaintarget
DB00541VincristineRalA-binding protein 1transporter
DB00541VincristineSolute carrier organic anion transporter family member 1B1transporter
DB00541VincristineSolute carrier organic anion transporter family member 1B3transporter
DB00565CisatracuriumNeuronal acetylcholine receptor subunit alpha-2target
DB00570VinblastineTubulin beta chaintarget
DB00570VinblastineTranscription factor AP-1target
DB00570VinblastineCytochrome P450 3A4enzyme
DB00570VinblastineP-glycoprotein 1transporter
DB00570VinblastineMultidrug resistance-associated protein 1transporter
DB00570VinblastineCanalicular multispecific organic anion transporter 1transporter
DB00570VinblastineMultidrug resistance-associated protein 6transporter
DB00570VinblastineBile salt export pumptransporter
DB00570VinblastineTubulin alpha-1A chaintarget
DB00570VinblastineTubulin delta chaintarget
DB00570VinblastineTubulin epsilon chaintarget
DB00570VinblastineTubulin gamma-1 chaintarget
DB00570VinblastineCytochrome P450 2D6enzyme
DB00570VinblastineSolute carrier organic anion transporter family member 1B1transporter
DB00572AtropineMuscarinic acetylcholine receptor M2target
DB00572AtropineMuscarinic acetylcholine receptor M1target
DB00572AtropineMuscarinic acetylcholine receptor M4target
DB00572AtropineMuscarinic acetylcholine receptor M5target
DB00572AtropineMuscarinic acetylcholine receptor M3target
DB00572AtropineGlycine receptor subunit alpha-1target
DB00572AtropineNeuronal acetylcholine receptor subunit alpha-4target
DB00572AtropineNeuronal acetylcholine receptor subunit beta-2target
DB00572AtropineBile salt export pumptransporter
DB00589LisurideDopamine D1 receptortarget
DB00589Lisuride5-hydroxytryptamine receptor 1Atarget
DB00589LisurideDopamine D2 receptortarget
DB00589LisurideAlpha-2A adrenergic receptortarget
DB00589LisurideAlpha-2B adrenergic receptortarget
DB00589LisurideAlpha-2C adrenergic receptortarget
DB00589LisurideDopamine D3 receptortarget
DB00589Lisuride5-hydroxytryptamine receptor 1Dtarget
DB00589Lisuride5-hydroxytryptamine receptor 2Btarget
DB00589Lisuride5-hydroxytryptamine receptor 2Atarget
DB00589LisurideDopamine D4 receptortarget
DB00589Lisuride5-hydroxytryptamine receptor 2Ctarget
DB00589LisurideDopamine D5 receptortarget
DB00589Lisuride5-hydroxytryptamine receptor 1Btarget
DB00589LisurideCytochrome P450 3A4enzyme
DB00589Lisuride5-hydroxytryptamine receptor 7target
DB00611ButorphanolKappa-type opioid receptortarget
DB00611ButorphanolMu-type opioid receptortarget
DB00611ButorphanolDelta-type opioid receptortarget
DB00651DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB00651DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB00651DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
DB00651DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB00651DyphyllineHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7Atarget
DB00651DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 7Btarget
DB00651DyphyllineAdenosine receptor A1target
DB00651DyphyllineAdenosine receptor A2atarget
DB00652PentazocineMu-type opioid receptortarget
DB00652PentazocineKappa-type opioid receptortarget
DB00652PentazocineSigma non-opioid intracellular receptor 1target
DB00674GalantamineAcetylcholinesterasetarget
DB00674GalantamineCytochrome P450 3A4enzyme
DB00674GalantamineCytochrome P450 2D6enzyme
DB00674GalantamineAcetylcholine receptor subunit alphatarget
DB00674GalantamineAcetylcholine receptor subunit betatarget
DB00674GalantamineAcetylcholine receptor subunit deltatarget
DB00674GalantamineAcetylcholine receptor subunit gammatarget
DB00674GalantamineAcetylcholine receptor subunit epsilontarget
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-2target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-3target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-4target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-5target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-6target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-7target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-9target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-10target
DB00674GalantamineNeuronal acetylcholine receptor subunit beta-2target
DB00674GalantamineNeuronal acetylcholine receptor subunit beta-3target
DB00674GalantamineNeuronal acetylcholine receptor subunit beta-4target
DB00674GalantamineCholinesterasetarget
DB00696ErgotamineAlpha-1A adrenergic receptortarget
DB00696Ergotamine5-hydroxytryptamine receptor 1Dtarget
DB00696Ergotamine5-hydroxytryptamine receptor 1Btarget
DB00696Ergotamine5-hydroxytryptamine receptor 2Atarget
DB00696ErgotamineAlpha-2A adrenergic receptortarget
DB00696ErgotamineDopamine D2 receptortarget
DB00696ErgotamineAlpha-2B adrenergic receptortarget
DB00696ErgotamineSodium-dependent noradrenaline transportertarget
DB00696ErgotamineCytochrome P450 3A4enzyme
DB00696ErgotamineAlpha-1B adrenergic receptortarget
DB00696ErgotamineAlpha-1D adrenergic receptortarget
DB00696ErgotamineP-glycoprotein 1transporter
DB00696ErgotamineD(1) dopamine receptortarget
DB00696Ergotamine5-hydroxytryptamine receptor 1Atarget
DB00696Ergotamine5-hydroxytryptamine receptor 1Ftarget
DB00696Ergotamine5-hydroxytryptamine receptor 2Ctarget
DB00696Ergotamine5-hydroxytryptamine receptor 2Btarget
DB00699NicergolineAlpha-1A adrenergic receptortarget
DB00699NicergolineCytochrome P450 2D6enzyme
DB00704NaltrexoneMu-type opioid receptortarget
DB00704NaltrexoneKappa-type opioid receptortarget
DB00704NaltrexoneDelta-type opioid receptortarget
DB00704NaltrexoneHCG20471, isoform CRA_ctarget
DB00704NaltrexoneUDP-glucuronosyltransferase 1-1enzyme
DB00714ApomorphineDopamine D2 receptortarget
DB00714ApomorphineDopamine D1 receptortarget
DB00714ApomorphineDopamine D4 receptortarget
DB00714ApomorphineDopamine D3 receptortarget
DB00714ApomorphineDopamine D5 receptortarget
DB00714ApomorphineNeuron-specific vesicular protein calcyontarget
DB00714ApomorphineAlpha-2C adrenergic receptortarget
DB00714ApomorphineAlpha-2B adrenergic receptortarget
DB00714Apomorphine5-hydroxytryptamine receptor 2Ctarget
DB00714Apomorphine5-hydroxytryptamine receptor 1Atarget
DB00714Apomorphine5-hydroxytryptamine receptor 2Atarget
DB00714Apomorphine5-hydroxytryptamine receptor 2Btarget
DB00714ApomorphineAlpha-2A adrenergic receptortarget
DB00714Apomorphine5-hydroxytryptamine receptor 1Dtarget
DB00714Apomorphine5-hydroxytryptamine receptor 1Btarget
DB00725Homatropine methylbromideMuscarinic acetylcholine receptor M2target
DB00725Homatropine methylbromideMuscarinic acetylcholine receptor M1target
DB00725Homatropine methylbromideMuscarinic acetylcholine receptor M4target
DB00725Homatropine methylbromideMuscarinic acetylcholine receptor M5target
DB00725Homatropine methylbromideMuscarinic acetylcholine receptor M3target
DB00732Atracurium besylateNeuronal acetylcholine receptor subunit alpha-2target
DB00747ScopolamineMuscarinic acetylcholine receptor M1target
DB00747ScopolamineSucrase-isomaltase, intestinaltarget
DB00747ScopolamineMuscarinic acetylcholine receptor M2target
DB00747ScopolamineMuscarinic acetylcholine receptor M3target
DB00747ScopolamineMuscarinic acetylcholine receptor M4target
DB00747ScopolamineMuscarinic acetylcholine receptor M5target
DB00747ScopolamineP-glycoprotein 1transporter
DB00747ScopolamineNeuronal acetylcholine receptor subunit alpha-4target
DB00747ScopolamineNeuronal acetylcholine receptor subunit beta-2target
DB00762IrinotecanDNA topoisomerase I, mitochondrialtarget
DB00762IrinotecanDNA topoisomerase 1target
DB00762IrinotecanCytochrome P450 3A4enzyme
DB00762IrinotecanCytochrome P450 3A5enzyme
DB00762IrinotecanUDP-glucuronosyltransferase 1-1enzyme
DB00762IrinotecanUDP-glucuronosyltransferase 1-9enzyme
DB00762IrinotecanLiver carboxylesterase 1enzyme
DB00762IrinotecanCytochrome P450 3A7enzyme
DB00762IrinotecanCytochrome P450 2B6enzyme
DB00762IrinotecanSolute carrier family 22 member 3transporter
DB00762IrinotecanSolute carrier organic anion transporter family member 1B1transporter
DB00762IrinotecanMultidrug resistance-associated protein 1transporter
DB00762IrinotecanATP-binding cassette sub-family G member 2transporter
DB00762IrinotecanSerum albumincarrier
DB00762IrinotecanCocaine esteraseenzyme
DB00762IrinotecanCholinesteraseenzyme
DB00762IrinotecanP-glycoprotein 1transporter
DB00762IrinotecanCanalicular multispecific organic anion transporter 1transporter
DB00785CryptenamineMuscarinic acetylcholine receptor M2target
DB00785CryptenamineMuscarinic acetylcholine receptor M1target
DB00785CryptenamineMuscarinic acetylcholine receptor M4target
DB00785CryptenamineMuscarinic acetylcholine receptor M5target
DB00785CryptenamineMuscarinic acetylcholine receptor M3target
DB00806PentoxifyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB00806PentoxifyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB00806Pentoxifylline5'-nucleotidasetarget
DB00806PentoxifyllinecGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00806PentoxifyllineAdenosine receptor A1target
DB00806PentoxifyllineAdenosine receptor A2atarget
DB00806PentoxifyllineCytochrome P450 1A2enzyme
DB00824EnprofyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB00824EnprofyllineAdenosine receptor A2btarget
DB00824EnprofyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB00824EnprofyllineAdenosine receptor A1target
DB00824EnprofyllineAdenosine receptor A2atarget
DB00824EnprofyllineAdenosine receptor A3target
DB00844NalbuphineKappa-type opioid receptortarget
DB00844NalbuphineMu-type opioid receptortarget
DB00844NalbuphineDelta-type opioid receptortarget
DB00854LevorphanolMu-type opioid receptortarget
DB00854LevorphanolDelta-type opioid receptortarget
DB00854LevorphanolKappa-type opioid receptortarget
DB00907CocaineSodium-dependent noradrenaline transportertarget
DB00907CocaineSodium channel protein type 5 subunit alphatarget
DB00907CocaineSodium channel protein type 11 subunit alphatarget
DB00907CocaineSodium channel protein type 10 subunit alphatarget
DB00907CocaineSodium-dependent serotonin transportertarget
DB00907CocaineSodium-dependent dopamine transportertarget
DB00907CocaineCytochrome P450 3A4enzyme
DB00907CocaineMuscarinic acetylcholine receptor M1target
DB00907CocaineMuscarinic acetylcholine receptor M2target
DB00907CocaineCytochrome P450 3A5enzyme
DB00907CocaineCytochrome P450 3A7enzyme
DB00907CocaineCytochrome P450 2D6enzyme
DB00907CocaineSolute carrier family 22 member 2transporter
DB00907CocaineCytochrome P450 2C8enzyme
DB00907CocaineSigma non-opioid intracellular receptor 1target
DB00907CocaineLiver carboxylesterase 1target
DB00907CocaineCholinesteraseenzyme
DB00908QuinidineSodium channel protein type 5 subunit alphatarget
DB00908QuinidineAlpha-1-acid glycoprotein 1carrier
DB00908QuinidinePotassium voltage-gated channel subfamily H member 2target
DB00908QuinidinePotassium channel subfamily K member 1target
DB00908QuinidinePotassium channel subfamily K member 6target
DB00908QuinidineCytochrome P450 1A2enzyme
DB00908QuinidineCytochrome P450 2E1enzyme
DB00908QuinidineCytochrome P450 1A1enzyme
DB00908QuinidineCytochrome P450 2D6enzyme
DB00908QuinidineCytochrome P450 3A4enzyme
DB00908QuinidineCytochrome P450 3A7enzyme
DB00908QuinidineSolute carrier family 22 member 2transporter
DB00908QuinidineSolute carrier family 22 member 1transporter
DB00908QuinidineSolute carrier family 22 member 5transporter
DB00908QuinidineP-glycoprotein 1transporter
DB00908QuinidineSolute carrier organic anion transporter family member 1A2transporter
DB00908QuinidineSolute carrier family 22 member 8transporter
DB00908QuinidineCanalicular multispecific organic anion transporter 1transporter
DB00908QuinidineSolute carrier family 22 member 4transporter
DB00908QuinidineSolute carrier organic anion transporter family member 1B1transporter
DB00908QuinidineCytochrome P450 2B6enzyme
DB00908QuinidineCytochrome P450 2C9enzyme
DB00908QuinidineAlpha-1A adrenergic receptortarget
DB00908QuinidineAlpha-1B adrenergic receptortarget
DB00908QuinidineAlpha-1D adrenergic receptortarget
DB00908QuinidineBile salt export pumptransporter
DB00908QuinidineCytochrome P450 2C8enzyme
DB00921BuprenorphineKappa-type opioid receptortarget
DB00921BuprenorphineMu-type opioid receptortarget
DB00921BuprenorphineCytochrome P450 3A4enzyme
DB00921BuprenorphineCytochrome P450 2D6enzyme
DB00921BuprenorphineP-glycoprotein 1transporter
DB00921BuprenorphineATP-binding cassette sub-family G member 2transporter
DB00921BuprenorphineCytochrome P450 2C9enzyme
DB00921BuprenorphineCytochrome P450 3A5enzyme
DB00921BuprenorphineCytochrome P450 2C8enzyme
DB00921BuprenorphineCytochrome P450 3A7enzyme
DB00921BuprenorphineDelta-type opioid receptortarget
DB00921BuprenorphineCytochrome P450 2C18enzyme
DB00921BuprenorphineCytochrome P450 2C19enzyme
DB00921BuprenorphineNociceptin receptortarget
DB00956HydrocodoneMu-type opioid receptortarget
DB00956HydrocodoneDelta-type opioid receptortarget
DB00956HydrocodoneCytochrome P450 3A4enzyme
DB00956HydrocodoneCytochrome P450 2D6enzyme
DB00956HydrocodoneCytochrome P450 2B6enzyme
DB00956HydrocodoneCytochrome P450 2C19enzyme
DB00956HydrocodoneSigma non-opioid intracellular receptor 1target
DB00981PhysostigmineAcetylcholinesterasetarget
DB00981PhysostigmineNeuronal acetylcholine receptor subunit alpha-4target
DB00981PhysostigmineNeuronal acetylcholine receptor subunit beta-2target
DB00985DimenhydrinateHistamine H1 receptortarget
DB01030TopotecanDNA topoisomerase I, mitochondrialtarget
DB01030TopotecanDNA topoisomerase 1target
DB01030TopotecanATP-binding cassette sub-family G member 2transporter
DB01030TopotecanP-glycoprotein 1transporter
DB01030TopotecanCytochrome P450 3A4enzyme
DB01030TopotecanDNAtarget
DB01030TopotecanMultidrug and toxin extrusion protein 1transporter
DB01030TopotecanMultidrug and toxin extrusion protein 2transporter
DB01049Ergoloid mesylateDopamine receptortarget
DB01049Ergoloid mesylateAlpha adrenergic receptortarget
DB01049Ergoloid mesylateBeta adrenergic receptortarget
DB01049Ergoloid mesylateSerotonin Receptorstarget
DB01049Ergoloid mesylateCytochrome P450 3A4enzyme
DB01085PilocarpineMuscarinic acetylcholine receptor M1target
DB01085PilocarpineMuscarinic acetylcholine receptor M2target
DB01085PilocarpineCytochrome P450 2A6enzyme
DB01085PilocarpineMuscarinic acetylcholine receptor M3target
DB01085PilocarpineCytochrome P450 3A4enzyme
DB01085PilocarpineMuscarinic acetylcholine receptor M4target
DB01089DeserpidineSynaptic vesicular amine transportertarget
DB01113PapaverinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB01113PapaverinecAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
DB01180RescinnamineAngiotensin-converting enzymetarget
DB01183NaloxoneMu-type opioid receptortarget
DB01183NaloxoneEstrogen receptor alphatarget
DB01183NaloxoneCyclic AMP-responsive element-binding protein 1target
DB01183NaloxoneDelta-type opioid receptortarget
DB01183NaloxoneSolute carrier organic anion transporter family member 1A2transporter
DB01183NaloxoneP-glycoprotein 1transporter
DB01183NaloxoneKappa-type opioid receptortarget
DB01183NaloxoneCytochrome P450 3A4enzyme
DB01183NaloxoneSerum albumincarrier
DB01183NaloxoneToll-like receptor 4target
DB01183NaloxoneLiver carboxylesterase 1target
DB01183NaloxoneUDP-glucuronosyltransferase 1-1enzyme
DB01186PergolideDopamine D2 receptortarget
DB01186PergolideDopamine D1 receptortarget
DB01186PergolideDopamine D3 receptortarget
DB01186Pergolide5-hydroxytryptamine receptor 1Atarget
DB01186PergolideAlpha-1A adrenergic receptortarget
DB01186PergolideAlpha-2A adrenergic receptortarget
DB01186PergolideAlpha-2B adrenergic receptortarget
DB01186PergolideAlpha-2C adrenergic receptortarget
DB01186PergolideAlpha-1B adrenergic receptortarget
DB01186PergolideAlpha-1D adrenergic receptortarget
DB01186PergolideDopamine D4 receptortarget
DB01186PergolideDopamine D5 receptortarget
DB01186Pergolide5-hydroxytryptamine receptor 1Btarget
DB01186Pergolide5-hydroxytryptamine receptor 1Dtarget
DB01186Pergolide5-hydroxytryptamine receptor 2Atarget
DB01186Pergolide5-hydroxytryptamine receptor 2Btarget
DB01186Pergolide5-hydroxytryptamine receptor 2Ctarget
DB01186PergolideCytochrome P450 2D6enzyme
DB01186PergolideCytochrome P450 3A4enzyme
DB01192OxymorphoneMu-type opioid receptortarget
DB01192OxymorphoneCytochrome P450 2D6enzyme
DB01192OxymorphoneDelta-type opioid receptortarget
DB01192OxymorphoneCytochrome P450 3A4enzyme
DB01199TubocurarineNeuronal acetylcholine receptor subunit alpha-2target
DB01199TubocurarineAcetylcholinesterasetarget
DB01199Tubocurarine5-hydroxytryptamine receptor 3Atarget
DB01199TubocurarineSolute carrier family 22 member 1transporter
DB01199TubocurarineSolute carrier family 22 member 2transporter
DB01199TubocurarineNeuronal acetylcholine receptor subunit alpha-7target
DB01199TubocurarineCholinesteraseenzyme
DB01200BromocriptineDopamine D2 receptortarget
DB01200BromocriptineCytochrome P450 3A4enzyme
DB01200Bromocriptine5-hydroxytryptamine receptor 1Dtarget
DB01200BromocriptineAlpha-2A adrenergic receptortarget
DB01200BromocriptineDopamine D3 receptortarget
DB01200Bromocriptine5-hydroxytryptamine receptor 1Atarget
DB01200BromocriptineAlpha-2C adrenergic receptortarget
DB01200BromocriptineAlpha-2B adrenergic receptortarget
DB01200Bromocriptine5-hydroxytryptamine receptor 2Btarget
DB01200BromocriptineDopamine D4 receptortarget
DB01200Bromocriptine5-hydroxytryptamine receptor 2Atarget
DB01200Bromocriptine5-hydroxytryptamine receptor 1Btarget
DB01200Bromocriptine5-hydroxytryptamine receptor 2Ctarget
DB01200BromocriptineDopamine D5 receptortarget
DB01200BromocriptineDopamine D1 receptortarget
DB01200BromocriptineAlpha-1A adrenergic receptortarget
DB01200BromocriptineAlpha-1B adrenergic receptortarget
DB01200BromocriptineAlpha-1D adrenergic receptortarget
DB01200Bromocriptine5-hydroxytryptamine receptor 7target
DB01200BromocriptineP-glycoprotein 1transporter
DB01223AminophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB01223AminophyllineAdenosine receptor A3target
DB01223AminophyllineAdenosine receptor A1target
DB01223AminophyllineCytochrome P450 1A2enzyme
DB01223AminophyllineCytochrome P450 2E1enzyme
DB01223AminophyllineCytochrome P450 3A4enzyme
DB01223AminophyllineHistone deacetylase 2target
DB01253ErgometrineCytochrome P450 3A4enzyme
DB01253ErgometrineP-glycoprotein 1transporter
DB01253ErgometrineAlpha-1A adrenergic receptortarget
DB01303OxtriphyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB01303OxtriphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB01303OxtriphyllineAdenosine receptor A2atarget
DB01303OxtriphyllineAdenosine receptor A1target
DB01303OxtriphyllineCytochrome P450 1A2enzyme
DB01303OxtriphyllineSolute carrier family 22 member 7transporter
DB01303OxtriphyllineHistone deacetylase 2target
DB01336MetocurineNeuronal acetylcholine receptor subunit alpha-2target
DB01336MetocurineMuscarinic acetylcholine receptor M2target
DB01392YohimbineAlpha-2A adrenergic receptortarget
DB01392YohimbineAlpha-2B adrenergic receptortarget
DB01392YohimbineAlpha-2C adrenergic receptortarget
DB01392Yohimbine5-hydroxytryptamine receptor 1Atarget
DB01392Yohimbine5-hydroxytryptamine receptor 1Btarget
DB01392Yohimbine5-hydroxytryptamine receptor 1Dtarget
DB01392YohimbineDopamine D2 receptortarget
DB01392YohimbineDopamine D3 receptortarget
DB01392Yohimbine5-hydroxytryptamine receptor 2Atarget
DB01392Yohimbine5-hydroxytryptamine receptor 2Ctarget
DB01392YohimbineCytochrome P450 2D6enzyme
DB01392YohimbineCytochrome P450 3A4enzyme
DB01392YohimbineATP-sensitive potassium channeltarget
DB01392Yohimbine5-hydroxytryptamine receptor 2Btarget
DB01394ColchicineTubulin beta chaintarget
DB01394ColchicineCytochrome P450 3A4enzyme
DB01394ColchicineP-glycoprotein 1transporter
DB01394ColchicineCytochrome P450 2B6enzyme
DB01394ColchicineCytochrome P450 2C8enzyme
DB01394ColchicineCytochrome P450 2E1enzyme
DB01394ColchicineSerum albumincarrier
DB01409TiotropiumMuscarinic acetylcholine receptor M3target
DB01409TiotropiumCytochrome P450 2D6enzyme
DB01409TiotropiumCytochrome P450 3A4enzyme
DB01409TiotropiumMuscarinic acetylcholine receptor M1target
DB01409TiotropiumMuscarinic acetylcholine receptor M2target
DB01409TiotropiumSolute carrier family 22 member 5transporter
DB01409TiotropiumSolute carrier family 22 member 4transporter
DB01409TiotropiumMuscarinic acetylcholine receptor M4target
DB01409TiotropiumMuscarinic acetylcholine receptor M5target
DB01412TheobromineCytochrome P450 1A2enzyme
DB01412TheobromineCytochrome P450 2E1enzyme
DB01412TheobromineAdenosine receptor A1target
DB01412TheobromineAdenosine receptor A2atarget
DB01412TheobrominecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB01426AjmalineAlpha-1-acid glycoprotein 1carrier
DB01426AjmalineSodium channel protein type 5 subunit alphatarget
DB01452DiamorphineMu-type opioid receptortarget
DB01452DiamorphineKappa-type opioid receptortarget
DB01452DiamorphineDelta-type opioid receptortarget
DB01452DiamorphineLiver carboxylesterase 1target
DB01452DiamorphineThyroxine-binding globulincarrier
DB01466EthylmorphineCytochrome P450 2D6enzyme
DB01466EthylmorphineNADPH--cytochrome P450 reductaseenzyme
DB01466EthylmorphineMu-type opioid receptortarget
DB01466EthylmorphineCytochrome P450 2B6enzyme
DB01466EthylmorphineCytochrome P450 3A4enzyme
DB01482FenethyllineCytochrome P450 1A2enzyme
DB01497EtorphineE3 ubiquitin-protein ligase TRIM13target
DB01497EtorphinePro-opiomelanocortintarget
DB01497EtorphineMu-type opioid receptortarget
DB01497EtorphineDelta-type opioid receptortarget
DB01497EtorphineKappa-type opioid receptortarget
DB01497EtorphineNociceptin receptortarget
DB01548DiprenorphineE3 ubiquitin-protein ligase TRIM13target
DB01548DiprenorphineDelta-type opioid receptortarget
DB01548DiprenorphineKappa-type opioid receptortarget
DB01548DiprenorphineMu-type opioid receptortarget
DB01551DihydrocodeineCytochrome P450 2D6enzyme
DB01551DihydrocodeineCytochrome P450 3A4enzyme
DB01565DihydromorphineE3 ubiquitin-protein ligase TRIM13target
DB01565DihydromorphinePro-opiomelanocortintarget
DB01565DihydromorphineMu-type opioid receptortarget
DB01565DihydromorphineDelta-type opioid receptortarget
DB01565DihydromorphineKappa-type opioid receptortarget
DB018758-AzaxanthineUric acid degradation bifunctional proteintarget
DB019337-Hydroxystaurosporine3-phosphoinositide-dependent protein kinase 1target
DB02010StaurosporineTyrosine-protein kinase Lcktarget
DB02010StaurosporineSerine/threonine-protein kinase pim-1target
DB02010StaurosporineTyrosine-protein kinase ITK/TSKtarget
DB02010StaurosporineTyrosine-protein kinase SYKtarget
DB02010StaurosporineMAP kinase-activated protein kinase 2target
DB02010StaurosporineGlycogen synthase kinase-3 betatarget
DB02010StaurosporineTyrosine-protein kinase CSKtarget
DB02010StaurosporineCyclin-dependent kinase 2target
DB02010StaurosporinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
DB02010Staurosporine3-phosphoinositide-dependent protein kinase 1target
DB02010StaurosporineProtein kinase C theta typetarget
DB02010StaurosporineTyrosine-protein kinase ZAP-70target
DB02010StaurosporineP-glycoprotein 1transporter
DB02010StaurosporineMuscarinic acetylcholine receptor M1target
DB02134XanthinePurine nucleoside phosphorylase 2target
DB02134XanthineXanthine phosphoribosyltransferasetarget
DB02134XanthineCytochrome P450 1A2enzyme
DB02152K-252aHepatocyte growth factor receptortarget
DB02152K-252aDual specificity mitogen-activated protein kinase kinase 1target
DB03206DuvoglustatCyclomaltodextrin glucanotransferasetarget
DB03206DuvoglustatBeta-glucosidase Atarget
DB03206DuvoglustatEndoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidasetarget
DB03206DuvoglustatMannosyl-oligosaccharide alpha-1,2-mannosidasetarget
DB03206DuvoglustatXylose isomerasetarget
DB04115BerberineHTH-type transcriptional regulator QacRtarget
DB04115BerberineBaculoviral IAP repeat-containing protein 5target
DB04365ArecolineMuscarinic acetylcholine receptor M1target
DB04365ArecolineMuscarinic acetylcholine receptor M3target
DB04688MethylecgonineIg gamma-2 chain C regiontarget
DB04688MethylecgonineIg kappa chain C regiontarget
DB04690CamptothecinDNA topoisomerase 1target
DB04690CamptothecinP-glycoprotein 1transporter
DB04690CamptothecinATP-binding cassette sub-family G member 2transporter
DB04690CamptothecinSerum albumincarrier
DB04829Lysergic acid diethylamide5-hydroxytryptamine receptor 1Atarget
DB04829Lysergic acid diethylamide5-hydroxytryptamine receptor 2Btarget
DB04829Lysergic acid diethylamide5-hydroxytryptamine receptor 6target
DB04829Lysergic acid diethylamideCytochrome P450 3A4enzyme
DB04829Lysergic acid diethylamideCytochrome P450 2D6enzyme
DB04865Omacetaxine mepesuccinate50S ribosomal protein L2target
DB04865Omacetaxine mepesuccinate60S ribosomal protein L3target
DB04877VoacamineP-glycoprotein 1target
DB04892PhenserineAcetylcholinesterasetarget
DB04892PhenserineCholinesterasetarget
DB04892PhenserineAmyloid beta A4 proteintarget
DB04947AltropaneSodium-dependent dopamine transportertarget
DB05018MigalastatAlpha-galactosidase Atarget
DB05018MigalastatUDP-glucuronosyltransferase 1-1enzyme
DB05137LobelineNeuronal acetylcholine receptor subunit alpha-9target
DB05137LobelineNeuronal acetylcholine receptor subunit alpha-10target
DB05137LobelineNeuronal acetylcholine receptor subunit alpha-7target
DB05168VintafolideFolate receptor betatarget
DB05168VintafolideFolate receptor gammatarget
DB05168VintafolideFolate receptor alphatarget
DB05806CositecanDNA topoisomerase 1target
DB05855RivaniclineNeuronal acetylcholine receptor subunit beta-2target
DB05855RivaniclineInterleukin-8target
DB06069XMT-1001DNA topoisomerase 1target
DB06159RubitecanDNA topoisomerase 1target
DB06174NoscapineSigma non-opioid intracellular receptor 1target
DB06174NoscapineCytochrome P450 2C9enzyme
DB06174NoscapineCytochrome P450 3A4enzyme
DB06230NalmefeneMu-type opioid receptortarget
DB06230NalmefeneKappa-type opioid receptortarget
DB06230NalmefeneDelta-type opioid receptortarget
DB06230NalmefeneUDP-glucuronosyltransferase 2B7enzyme
DB06230NalmefeneUDP-glucuronosyltransferase 1-3enzyme
DB06230NalmefeneUDP-glucuronosyltransferase 1-8enzyme
DB06471NaxifyllineAdenosine receptor A1target
DB06479PropentofyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB06479PropentofyllineCytochrome P450 1A2enzyme
DB06595MidostaurinProtein kinase C alpha typetarget
DB06595MidostaurinVascular endothelial growth factor receptor 2target
DB06595MidostaurinMast/stem cell growth factor receptor Kittarget
DB06595MidostaurinPlatelet-derived growth factor receptor alphatarget
DB06595MidostaurinPlatelet-derived growth factor receptor betatarget
DB06595MidostaurinReceptor-type tyrosine-protein kinase FLT3target
DB06595MidostaurinCytochrome P450 3A Subfamilyenzyme
DB06595MidostaurinCytochrome P450 1A2enzyme
DB06595MidostaurinCytochrome P450 2B6enzyme
DB06595MidostaurinCytochrome P450 2C8enzyme
DB06595MidostaurinCytochrome P450 2C9enzyme
DB06595MidostaurinCytochrome P450 2C19enzyme
DB06595MidostaurinCytochrome P450 2D6enzyme
DB06595MidostaurinCytochrome P450 2E1enzyme
DB06595MidostaurinCytochrome P450 3A4enzyme
DB06595MidostaurinCytochrome P450 3A5enzyme
DB06595MidostaurinCytochrome P450 3A7enzyme
DB06595MidostaurinCytochrome P450 3A43enzyme
DB06721GimatecanSolute carrier organic anion transporter family member 1B1transporter
DB06727SparteineCytochrome P450 2D6enzyme
DB06751DrotaverinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB06751DrotaverineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB06774CapsaicinCytochrome P450 3A4enzyme
DB06774CapsaicinProstaglandin G/H synthase 2enzyme
DB06774CapsaicinMyeloperoxidaseenzyme
DB06774CapsaicinCytochrome P450 1A2enzyme
DB06774CapsaicinCytochrome P450 2E1enzyme
DB06774CapsaicinAmine oxidase [flavin-containing] Aenzyme
DB06774CapsaicinDopamine beta-hydroxylaseenzyme
DB06774CapsaicinGlutamine synthetaseenzyme
DB06774CapsaicinCholinesteraseenzyme
DB06774CapsaicinTransient receptor potential cation channel subfamily V member 1target
DB06774CapsaicinProhibitin-2target
DB06800MethylnaltrexoneMu-type opioid receptortarget
DB06800MethylnaltrexoneKappa-type opioid receptortarget
DB079543-isobutyl-1-methyl-7H-xanthinecGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB079543-isobutyl-1-methyl-7H-xanthinecGMP-inhibited 3',5'-cyclic phosphodiesterase Btarget
DB079543-isobutyl-1-methyl-7H-xanthineHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7Atarget
DB079543-isobutyl-1-methyl-7H-xanthinecAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB079543-isobutyl-1-methyl-7H-xanthineHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9Atarget
DB079543-isobutyl-1-methyl-7H-xanthineHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8Atarget
DB079543-isobutyl-1-methyl-7H-xanthinecGMP-dependent 3',5'-cyclic phosphodiesterasetarget
DB079543-isobutyl-1-methyl-7H-xanthineRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB08824Ioflupane I-123Sodium-dependent dopamine transportertransporter
DB08844Uric acidSolute carrier family 22 member 6transporter
DB08844Uric acidSolute carrier family 22 member 8transporter
DB08844Uric acidGlycogen phosphorylase, liver formtarget
DB08844Uric acidSolute carrier family 2, facilitated glucose transporter member 9transporter
DB08897AclidiniumMuscarinic acetylcholine receptor M1target
DB08897AclidiniumMuscarinic acetylcholine receptor M2target
DB08897AclidiniumMuscarinic acetylcholine receptor M3target
DB08897AclidiniumMuscarinic acetylcholine receptor M4target
DB08897AclidiniumMuscarinic acetylcholine receptor M5target
DB08897AclidiniumCholinesteraseenzyme
DB09049NaloxegolCytochrome P450 3A4enzyme
DB09049NaloxegolCytochrome P450 2D6enzyme
DB09049NaloxegolCytochrome P450 2C19enzyme
DB09049NaloxegolMu-type opioid receptortarget
DB09092Xanthinol60S ribosomal protein L3target
DB09092XanthinolNAD(P) transhydrogenase, mitochondrialtarget
DB09092XanthinolGlyceraldehyde-3-phosphate dehydrogenasetarget
DB09092XanthinolIsocitrate dehydrogenase [NAD] subunit alpha, mitochondrialtarget
DB09092Xanthinol2-oxoglutarate dehydrogenase, mitochondrialtarget
DB09092XanthinolMalate dehydrogenase, mitochondrialtarget
DB09120ZucapsaicinTransient receptor potential cation channel subfamily V member 1target
DB09120ZucapsaicinCytochrome P450 1A2enzyme
DB09120ZucapsaicinCytochrome P450 2C19enzyme
DB09120ZucapsaicinCytochrome P450 2C9enzyme
DB09120ZucapsaicinCytochrome P450 2E1enzyme
DB09209PholcodineMu-type opioid receptortarget
DB09209PholcodineKappa-type opioid receptortarget
DB09209PholcodineDelta-type opioid receptortarget
DB09273DoxofyllinePhosphodiesterase 2A, cGMP-stimulatedtarget
DB09273DoxofyllineAdenosine receptor A2atarget
DB09273DoxofyllineBeta-2 adrenergic receptortarget
DB09273DoxofyllineCytochrome P450 1A2enzyme
DB09300ButylscopolamineMuscarinic acetylcholine receptor M3target
DB09300ButylscopolamineMuscarinic acetylcholine receptor M2target
DB11181HomatropineLiver carboxylesterase 1enzyme
DB11181HomatropineMuscarinic acetylcholine receptor M1target
DB11181HomatropineMuscarinic acetylcholine receptor M2target
DB11181HomatropineMuscarinic acetylcholine receptor M3target
DB11181HomatropineMuscarinic acetylcholine receptor M4target
DB11181HomatropineMuscarinic acetylcholine receptor M5target
DB11273DihydroergocornineSerotonin Receptorstarget
DB11273DihydroergocornineBeta adrenergic receptortarget
DB11273DihydroergocornineAlpha adrenergic receptortarget
DB11273DihydroergocornineCytochrome P450 3A4enzyme
DB11275EpicriptineDopamine receptortarget
DB11324NonivamideTransient receptor potential cation channel subfamily V member 1target
DB11582ThiocolchicosideGABA-A receptor (anion channel)target
DB11582ThiocolchicosideGlycine receptor subunit alpha-1target
DB11582ThiocolchicosideTumor necrosis factor ligand superfamily member 11target
DB11641VinflunineATP-binding cassette sub-family B member 5transporter
DB11641VinflunineP-glycoprotein 1transporter
DB11641VinflunineSerum albumincarrier
DB11641Vinfluninealpha1-acid glycoproteincarrier
DB11641VinflunineCytochrome P450 3A4enzyme
DB11641VinflunineTubulin beta chaintarget
DB11785AnisodamineCytochrome P450 2D6enzyme
DB12093TetrahydropalmatineDopamine D1 receptortarget
DB12093TetrahydropalmatineDopamine D2 receptortarget
DB12093TetrahydropalmatineCytochrome P450 3A4enzyme
DB12131VinpocetineCytochrome P450 3A4enzyme
DB12406LisofyllineCytochrome P450 1A2enzyme
DB125159-aminocamptothecinCytochrome P450 3A4enzyme
DB12569TonapofyllineAdenosine receptor A1target
DB12670RolofyllineAdenosine receptor A1target
DB13141Ambroxol acefyllinateCytochrome P450 3A Subfamilyenzyme
DB13203BamifyllineCytochrome P450 1A2enzyme
DB13345DihydroergocristineSerotonin Receptorstarget
DB13345DihydroergocristineBeta adrenergic receptortarget
DB13345DihydroergocristineAlpha adrenergic receptortarget
DB13345DihydroergocristineDopamine receptortarget
DB13345DihydroergocristineBile salt export pumptransporter
DB13345DihydroergocristineCytochrome P450 3A4enzyme
DB13385DihydroergocryptineCytochrome P450 3A4enzyme
DB13399TergurideCytochrome P450 3A4enzyme
DB13449ProxyphyllineCytochrome P450 1A2enzyme
DB13520MetergolineSodium channel protein type 2 subunit alphatarget
DB13573AcefyllineCytochrome P450 1A2enzyme
DB13592EtamiphyllineCytochrome P450 1A2enzyme
DB13634PentifyllineCytochrome P450 1A2enzyme
DB13812BufyllineCytochrome P450 1A2enzyme
DB13875HarmalineHistamine N-methyltransferasetarget
DB14018BromotheophyllineCytochrome P450 1A2enzyme
DB14029FurafyllineCytochrome P450 1A2enzyme
DB14066TetrandrineP-glycoprotein 1target
DB14066TetrandrineCytochrome P450 3A4enzyme
DB141328-chlorotheophyllineAdenosine receptor A2atarget
DB141328-chlorotheophyllineCytochrome P450 1A2enzyme
DB054827-ethyl-10-hydroxycamptothecinDNA topoisomerase 1target
DB054827-ethyl-10-hydroxycamptothecinCytochrome P450 3A4enzyme
DB09363Rauwolfia serpentina rootSynaptic vesicular amine transportertarget
DB09363Rauwolfia serpentina rootMonoamine oxidaseenzyme
DB09363Rauwolfia serpentina rootSodium-dependent noradrenaline transportertransporter
DB09363Rauwolfia serpentina rootvesicular monoamine transporter 2 (VMAT2)transporter
DB01430AlmitrineSodium/potassium-transporting ATPase subunit alpha-1target
DB06409Morphine glucuronideMu-type opioid receptortarget
DB06409Morphine glucuronideDelta-type opioid receptortarget
DB06409Morphine glucuronideKappa-type opioid receptortarget
DB11691NaldemedineCytochrome P450 3A Subfamilyenzyme
DB11691NaldemedineUDP-glucuronosyltransferase 1-3enzyme
DB11691NaldemedineMu-type opioid receptortarget
DB11691NaldemedineDelta-type opioid receptortarget
DB11691NaldemedineKappa-type opioid receptortarget
DB11691NaldemedineATP-binding cassette sub-family B member 5transporter
DB14146LoxicodegolMu-type opioid receptortarget
DB14146LoxicodegolDelta-type opioid receptortarget
DB14146LoxicodegolKappa-type opioid receptortarget
DB14146LoxicodegolP-glycoprotein 1transporter