Name
Sulfones
Accession Number
DBCAT000515
Description
Not Available
Drugs
DrugDrug Description
DapsoneA sulfone drug used to treat acne vulgaris, Hansen's disease, and dermatitis herpetiformis.
SildenafilA phosphodiesterase inhibitor used for the treatment of erectile dysfunction.
DofetilideA class III antiarrhythmic drug used for the maintenance of normal sinus rhythm and cardioversion in cases of atrial fibrillation and atrial flutter.
TorasemideA diuretic used to treat hypertension and edema associated with heart failure, renal failure, or liver disease.
GlimepirideA sulfonylurea drug used to treat type 2 diabetes mellitus.
MethyclothiazideA diuretic drug used to treat hypertension and edema caused by heart failure, renal conditions, treatment with corticosteroids, and estrogen therapy.
SulfanilamideA sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans.
SulfisoxazoleA sulfonamide antibiotic used with other antibiotics to prevent and treat a variety of bacterial infections.
IbutilideA class III antiarrhythmic agent used to correct atrial fibrillation and atrial flutter, which can be considered as an alternative to cardioversion.
ChlorthalidoneA diuretic used to treat hypertension or edema caused by heart failure, renal failure, hepatic cirrhosis, estrogen therapy, and other conditions.
EthoxzolamideFor use in the treatment of duodenal ulcers, as a diuretic, and in the treatment of glaucoma, and may also be useful in the treatment of seizures associated with epilepsy.
SulfadiazineA sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid.
AcetohexamideUsed in the management of diabetes mellitus type 2 (adult-onset).
BendroflumethiazideA diuretic used to suppress lactation and to treat hypertension and edema.
CelecoxibAn NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis.
MetolazoneA thiazide-like diuretic used to treat hypertension.
ZafirlukastA leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma.
BosentanA dual endothelin receptor antagonist used to treat pulmonary arterial hypertension.
BenzthiazideFor the treatment of high blood pressure and management of edema.
SulfamethizoleA sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections.
ValdecoxibA COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea.
CyclothiazideCyclothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either...
SulfacetamideA corticosteroid used to treat inflammatory ocular conditions and acne vulgaris.
SulfametopyrazineFor the treatment of urinary tract infection and chronic bronchitis.
SumatriptanA serotonin receptor agonist used to treat migraines and cluster headaches.
ChlorpropamideA sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.
FurosemideA loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension.
AmprenavirA protease inhibitor used to treat HIV infection.
TamsulosinAn alpha-1A and alpha-1B adrenergic receptor antagonist used to treat benign prostatic hyperplasia, ureteral stones, prostatitis, and female voiding dysfunction.
HydroflumethiazideA thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure and liver cirrhosis.
SulfasalazineAn anti-inflammatory drug used to treat Crohn's disease and rheumatoid arthritis.
IndapamideA thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure.
Sodium lauryl sulfateAn anionic surfactant used in cosmetics and pharmaceuticals as a fat emulsifier, wetting agent, and detergent.
TolazamideA sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.
DorzolamideA carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma.
ChlorothiazideA thiazide diuretic used to treat hypertension and edema in congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy.
BumetanideA sulfamyl diuretic used to treat edema in congestive heart failure, hepatic and renal disease, and nephrotic syndrome.
SulfapyridineA sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum.
HydrochlorothiazideA thiazide diuretic used to treat edema associated with a number of conditions, and hypertension.
SulfamethoxazoleAn oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract.
GlyburideA sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.
TrichlormethiazideUsed in the treatment of oedema (including that associated with heart failure) and hypertension.
ProbenecidA medication used to treat gouty arthritis, tophaceous gout, and hyperuricemia.
GlipizideA sulfonylurea medication used in Type 2 Diabetes to sensitize pancreatic beta cells and stimulate insulin release.
RosuvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
DiazoxideA non diuretic benzothiadiazine indicated for the management of hypoglycemia in patients who produce an excess of insulin caused by a variety of conditions.
GliclazideA sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus.
TolbutamideA sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus.
BicalutamideAn androgen receptor inhibitor used to treat Stage D2 metastatic carcinoma of the prostate.
DiclofenamideA carbonic anhydrase inhibitor used for the management of open-angle and secondary glaucoma, as well as acute angle-closure glaucoma in delayed pre-operative setting requiring a reduction in intraocular pressure.
SulfoxoneFor the treatment of leprosy and dermatitis herpetiformis
BrinzolamideA carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
GliquidoneUsed in the treatment of diabetes mellitus type 2.
DarunavirA HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.
GlisoxepideFor the treatment of diabetes mellitus type 2.
SulfacytineUsed orally in the treatment of acute urinary tract infections.
SulfadoxineA long acting sulfonamide used for the treatment or prevention of malaria.
FosamprenavirAn antiretroviral agent used for the treatment and postexposure prophylaxis of human immunodeficiency virus (HIV-1) infection.
PolythiazideA thiazide diuretic used in the management of hypertension and treatment of edema.
QuinethazoneUsed to treat hypertension.
GlymidineGlycodiazine is used concomitantly with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus.
SulfamerazineAn antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections.
SulfamethazineAn antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections.
SC-74020Not Available
WAY-151693Not Available
DansylamideNot Available
PiretanidePiretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine...
N,O-Didansyl-L-TyrosineNot Available
N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideNot Available
HydroxyfasudilNot Available
NimesulideFor the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old.
BelinostatA histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL).
INCB13739Investigated for use/treatment in diabetes mellitus type 2 and diabetes prevention.
SLV319Investigated for use/treatment in obesity.
CimicoxibInvestigated for use/treatment in depression.
KD3010Investigated for use/treatment in metabolic disease and obesity.
XL765For the treatment of various forms of cancer.
Silver sulfadiazineA topical sulfonamide antibiotic that acts on the bacterial cell wall and cell membrane; approved for the treatment of burns.
Actelion-1Investigated for use/treatment in cardiovascular disorders, hypertension, and pulmonary hypertension.
AMG-131Investigated for use/treatment in diabetes mellitus type 2.
NaluzotanInvestigated for use/treatment in anxiety disorders and depression.
LaromustineInvestigated for use/treatment in brain cancer, cancer/tumors (unspecified), colorectal cancer, leukemia (lymphoid), leukemia (myeloid), lung cancer, myelodysplastic syndrome, pediatric indications, and solid tumors.
ResatorvidInvestigated for use/treatment in sepsis and septicemia.
SulfathiazoleSulfathiazole is effective against a wide range of gram positive and gram negative pathogenic microorganisms. Although no longer used in humans, it is used in cattle.
SulfadimethoxineFor use in the treatment of infections.
UdenafilInvestigated for use/treatment in erectile dysfunction and hypertension.
SimeprevirA direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4.
RefametinibInvestigated for use/treatment in cancer/tumors (unspecified).
ElinogrelInvestigated for use/treatment in cardiovascular disorders and myocardial infarction.
IndisulamInvestigated for use/treatment in lung cancer.
PazopanibAn antineoplastic agent used in the treatment of advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy.
ClazosentanInvestigated for use/treatment in strokes.
SulfaphenazoleFor the treatment bacterial infections.
MafenideAn antimicrobial topical agent indicated for use as an adjunctive treatment to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds.
SulfameterLong acting sulfonamide used in leprosy, urinary, and respiratory tract infections.
TO-901317TO-901317 is an LXRalpha and LXRbeta agonist.
5-(2-methylpiperazine-1-sulfonyl)isoquinolineNot Available
4-(2-AMINOETHYL)BENZENESULFONAMIDENot Available
PipazethateFor the treatment of cough.
SulfamoxoleFor the treatment of bacterial infection.
VemurafenibA kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation.
MacitentanAn endothelin receptor antagonist used to manage pulmonary arterial hypertension to delay disease progression.
AzosemideAzosemide is a loop diuretic used to treat hypertension, edema, and ascites.
GlibornurideGlibornuride is a sulfonylurea-type anti-diabetic drug.
BlinatumomabAn antineoplastic antibody used to treat Philadelphia chromosome-negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL).
DasabuvirA direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
SulfabenzamideA sulfonamide antibacterial used as an ingredient in various topical and vaginal preparations to treat certain infections, but has been discontinued by the FDA.
ClorsulonNot Annotated
DeracoxibDeracoxib is a non-steroidal anti-inflammatory drug of the coxib class, used in veterinary medicine to treat osteoarthritis in dogs. It is sold in tablets, which have added beefy flavour to...
SulfachlorpyridazineA sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.
SulfaethoxypyridazineNot Annotated
SulfanitranNot Annotated
SulfaquinoxalineSulfaquinoxaline is a veterinary medicine which can be given to cattle and sheep to treat coccidiosis.It is available in Pakistan with Sanna Laboratories in combination with Amprolium and Vitamin K...
AsunaprevirAsunaprevir is indicated in combination with other agents for the treatment of chronic hepatitis C in adult patients with hepatitis C virus genotypes 1 or 4 and compensated liver cirrhosis....
PictilisibPictilisib has been used in trials studying the treatment of Solid Cancers, Breast Cancer, Advanced Solid Tumours, Metastatic Breast Cancer, and Non-Hodgkin's Lymphoma, Solid Cancers, among others.
PavinetantPavinetant has been used in trials studying the basic science and treatment of Safety and Schizophrenia.
EncorafenibA kinase inhibitor used to treat unresectable or metastatic melanoma with specific mutations.
VonoprazanVonoprazan has been used in trials studying the treatment of Erosive Esophagitis.
PilaralisibPilaralisib is an orally available small molecule that selectively inhibits the activity of phosphoinositide-3 kinase (PI3K). Pilaralisib has been used in trials studying the treatment of Cancer, Lymphoma, Solid Tumors,...
DanoprevirDanoprevir has been used in trials studying the treatment of Hepatitis C, Chronic.
MirodenafilMirodenafil has been used in trials studying the treatment and supportive care of Kidney Diseases, Urologic Diseases, Renal Insufficiency, Erectile Dysfunction, and Male Erectile Dysfunction.
AZD-5672Azd5672 has been used in trials studying the basic science and treatment of Pharmacokinetics, Renal Impairment, and Rheumatoid Arthritis.
BaricitinibA Janus kinase inhibitor used to treat moderate to severe rheumatoid arthritis that has responded poorly to at least one TNF antagonist.
TMC-647055TMC647055 has been used in trials studying the treatment of Hepatitis C, Chronic Hepatitis C, Hepatitis C, Chronic, and Chronic Hepatitis C Virus.
PF-04958242PF-04958242 has been used in trials studying the basic science and treatment of Schizophrenia and Hearing Loss, Sensorineural.
LitronesibLitronesib has been used in trials studying the treatment of Solid Tumors, Ovarian Cancer, Gastric Cancer, Prostate Cancer, and Acute Leukaemia, among others.
PF-00610355PF-00610355 has been used in trials studying the treatment of Lung Disease, Moxifloxacin, Pulmonary Disease, Asthma, Bronchial, and Bronchial Diseases, among others.
AvagacestatAvagacestat has been investigated for the basic science and treatment of Alzheimer Disease.
GisadenafilGisadenafil has been investigated for the treatment of Prostatic Hyperplasia.
TasisulamTasisulam has been used in trials studying the treatment and basic science of Melanoma, Lymphoma, Solid Tumors, Breast Cancer, and Ovarian Cancer, among others.
SetrobuvirSetrobuvir has been used in trials studying the treatment of Hepatitis C, Chronic.
T-900607T900607 has been used in trials studying the treatment of Liver Cancer and Gastric Cancer.
ElubrixinElubrixin has been used in trials studying the treatment of Cystic Fibrosis, Colitis, Ulcerative, and Chronic Obstructive Pulmonary Disease (COPD).
PresatovirPresatovir has been used in trials studying the treatment of RSV Infection, Respiratory Syncytial Virus (RSV), Respiratory Syncytial Virus Infections, and Respiratory Syncytial Virus (RSV) Infections.
IguratimodIguratimod is under investigation in Rheumatoid Arthritis.
ABT-751ABT-751 has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.
BegacestatBegacestat has been used in trials studying the treatment and basic science of Alzheimer Disease.
VidupiprantVidupiprant has been used in trials studying the treatment and basic science of Asthma.
NavitoclaxNavitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, among others. Navitoclax is...
ApricoxibApricoxib has been used in trials studying the treatment and prevention of Lung Cancer, Breast Cancer, Pancreatic Cancer, Non Small Cell Lung Cancer, and Metastatic Pancreatic Cancer, among others.
ResminostatResminostat has been used in trials studying the treatment of Sezary Syndrome, Mycosis fungoides, Hodgkin's Lymphoma, Hepatocellular Carcinoma, and Lymphoma, T-Cell, Cutaneous, among others.
PolmacoxibPolmacoxib has been used in trials studying the treatment of Osteoarthritis, Osteoarthritis, Hip, Osteoarthritis, Knee, Localized Primary Osteoarthritis of Hip, and Localized Primary Osteoarthritis of Knee.
VoxtalisibVoxtalisib has been used in trials studying the treatment of Cancer, Melanoma, Lymphoma, Glioblastoma, and Breast Cancer, among others.
FedratinibFedratinib is indicated to treat adults with primary or secondary myelofibrosis that is either intermediate-2 or high risk.
E-7820E7820 has been investigated for the treatment of Colon Cancer and Rectal Cancer.
ReparixinReparixin has been used in trials studying the treatment and prevention of Breast Cancer, Metastatic Breast Cancer, Pancreatectomy for Chronic Pancreatitis, Islet Transplantation in Diabetes Mellitus Type 1, and Pancreatic...
TaprenepagTaprenepag has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle.
IbipinabantIbipinabant has been used in trials studying the treatment of Obesity and Obesity and Type 2 Diabetes.
OmipalisibOmipalisib has been used in trials studying the treatment of CANCER, Solid Tumours, and Idiopathic Pulmonary Fibrosis.
MibampatorMibampator has been used in trials studying the treatment of Alzheimer's Disease.
CHF-6001CHF6001 has been used in trials studying the treatment of Asthma and Chronic Obstructive Pulmonary Disease.
AtaciguatAtaciguat has been investigated for the basic science of Aortic Valve Stenosis.
GrapiprantThe effects of grapiprant have been investigated in the area of analgesia and anti-inflammation due to the effects that have been reported about this molecule. This molecule has been approved...
SivelestatSivelestat has been used in trials studying the treatment of Acute Lung Injury and Respiratory Distress Syndrome, Adult.
ChlorsulfaquinoxalineChlorsulfaquinoxaline has been used in trials studying the treatment of Lung Cancer and Colorectal Cancer.
RamatrobanRamatroban has been used in trials studying the treatment of Asthma.
CH-5132799CH5132799 has been used in trials studying the treatment of Solid Tumors.
UpamostatUpamostat has been used in trials studying the treatment of Pancreatic Cancer.
RipasudilRipasudil has been proven to be effective in the twice daily treatment of glaucoma and ocular hypertension. It is currently in studies to be approved for both diabetic retinopathy and...
PhthalylsulfathiazolePhthalylsulfathiazole is a broad spectrum antibiotic which is part of the drug class, sulfonamides. It was used as an antibiotic for bowel surgery, and for infections of the colon .
SulfaisodimidineSulfaisodimidine also called sulfisomidine is an antibacterial product that has been studied for the treatment of urinary tract infections in the 1950s, however, it is unclear whether this drug has...
MefrusideNot Annotated
CarbutamideNot Annotated
MebutizideNot Annotated
CyclopenthiazideCyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients...
SulfatolamideNot Annotated
SuccinylsulfathiazoleNot Annotated
ClorexoloneNot Annotated
MetahexamideNot Annotated
SulfathioureaNot Annotated
SulfaguanidineNot Annotated
SulfamethoxypyridazineNot Annotated
ClopamideClopamide is an oral diuretic agent with antihypertensive activity. Like thiazide diuretics, it has an aromatic sulfonamide base but with no double-ring structure.
XipamideNot Annotated
SB-269970SB-269970 is an experimental drug developed by GlaxoSmithKline. In the studies performed with this agent, it has been suggested that SB-269970 acts either as a selective antagonist or inverse agonist...
Acetyl sulfisoxazoleAcute, recurrent or chronic urinary tract infections (primarily pyelonephritis, pyelitis and cystitis) due to susceptible organisms (usually Escherichia coli, Klebsiella-Enterobacter, staphylococcus, Proteus mirabilis and, less frequently, Proteus vulgaris) in the...
SC-236SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) that has been studied in cancer therapy , lower back pain , and inflammation , , , .
NS-398NS-398 is a COX-2 inhibitor. It was developed as part of the mechanistic study of the cyclooxygenases.
Estradiol sulfamateInvestigated for use/treatment in endometriosis.
TosylchloramideTosylchloramide, also known as chloramine-T, is a chlorinated and deprotonated sulfonamide used as a mild disinfectant. It is not stable in the water dissolved form.
NesbuvirNesbuvir has been investigated for the treatment of Hepatitis C.
FasudilFasudil has been investigated in Carotid Stenosis.
VenetoclaxA BCL-2 inhibitor used to treat chronic lymphocytic leukemia, small lymphocytic lymphoma, or acute myeloid leukemia.
ABT-639ABT-639 is under investigation in clinical trial NCT01345045 (A Multicenter Study Comparing the Analgesic Effects and Safety of ABT-639 Compared to Placebo in Subjects With Diabetic Neuropathic Pain).
AprocitentanAprocitentan is under investigation in clinical trial NCT03541174 (A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and...
DubermatinibDubermatinib is under investigation in clinical trial NCT03572634 (Phase 1/2 Study of TP-0903 (an Inhibitor of AXL Kinase) in Patients With Previously Treated CLL).
JNJ-26489112JNJ-26489112 is under investigation in clinical trial NCT00579384 (A Study of the Effects of JNJ-26489112 on the Photic Induced Paroxysmal Electroencephalogram (EEG) Response in Patients With Photosensitive Epilepsy).
VercirnonVercirnon is a novel, orally active anti-inflammatory agent that targets a chemokine receptor protein implicated in both Crohn's disease and ulcerative colitis, the two principal forms of IBD. It is...
FlorasulamFlorasulam is under investigation in clinical trial NCT01193465 (Temperature and Humidity Among Different Anesthesia Work-station).
VM4-037VM4-037 is under investigation in clinical trial NCT00884520 (An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037).
GiripladibGiripladib is under investigation in clinical trial NCT00396955 (A Study Comparing 4 Dose Regimens of PLA-695, Naproxen, and Placebo In Subjects With Osteoarthritis Of The Knee).
ZonisamideA sulfonamide anticonvulsant used to treat partial seizures.
TazobactamA beta lactamase inhibitor administered with antibiotics such as piperacillin and ceftolozane to prevent their degradation, resulting in increased efficacy.
EtoricoxibFor the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout.
EpacadostatEpacadostat has been used in trials studying the treatment of HL, Melanoma, Glioblastoma, Mucosal Melanoma, and Ovarian Carcinoma, among others.
PF-00489791PF-00489791 has been used in trials studying the treatment of Hypertension, Raynaud's Disease, Diabetic Nephropathies, Hypertension, Pulmonary, and Peripheral Vascular Disease.
VoxilaprevirA nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections.
DefactinibDefactinib has been investigated for the treatment of Malignant Pleural Mesothelioma.
GLPG-0187GLPG0187 has been used in trials studying the treatment of Solid Tumors.
GlecaprevirA Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C.
LanifibranorLanifibranor is under investigation in clinical trial NCT03008070 (Phase 2b Study in NASH to Assess IVA337).
PF-05089771PF-05089771 is under investigation in clinical trial NCT01529671 (A Safety And Tolerability Study Of PF-05089771 In Healthy Subjects And In Subjects With Otseoarthritis Of The Knee).
TAK-243TAK-243 is under investigation in clinical trial NCT03816319 (TAK-243 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Refractory Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia).
ABT-072ABT-072 is under investigation in clinical trial NCT00890318 (A Study in Healthy Adult Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetic Profiles of Multiple Doses of ABT-072 Used to Treat...
PLX-4720Not Available
GW-813893Not Available
CGS-27023Not Available
H-89Not Available
FasitibantFasitibant is under investigation in clinical trial NCT02205814 (Fasitibant Intra-articular Injection in Patients With Symptomatic Osteoarthritis of the Knee).
Drugs & Drug Targets
DrugTargetType
DapsoneInactive dihydropteroate synthase 2target
DapsoneDihydropteroate synthase 1target
DapsoneCytochrome P450 2C9enzyme
DapsoneCytochrome P450 2E1enzyme
DapsoneCytochrome P450 3A4enzyme
DapsoneDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DapsoneProstaglandin G/H synthase 1enzyme
DapsoneProstaglandin G/H synthase 2enzyme
DapsoneCytochrome P450 2C8enzyme
DapsoneCytochrome P450 2C19enzyme
DapsoneArylamine N-acetyltransferase 2enzyme
DapsoneCytochrome P450 3A5enzyme
DapsoneCytochrome P450 3A7enzyme
DapsoneMyeloperoxidaseenzyme
DapsoneCytochrome P450 2C18enzyme
SildenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
SildenafilCytochrome P450 2C9enzyme
SildenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
SildenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
SildenafilCytochrome P450 3A4enzyme
SildenafilCytochrome P450 3A5enzyme
SildenafilCytochrome P450 3A7enzyme
SildenafilMultidrug resistance-associated protein 4transporter
SildenafilMultidrug resistance-associated protein 5transporter
SildenafilMultidrug resistance-associated protein 7transporter
SildenafilCytochrome P450 2C19enzyme
SildenafilCytochrome P450 2D6enzyme
SildenafilCytochrome P450 2E1enzyme
SildenafilSolute carrier organic anion transporter family member 1B1transporter
SildenafilP-glycoprotein 1transporter
DofetilidePotassium channel subfamily K member 2target
DofetilidePotassium voltage-gated channel subfamily H member 2target
DofetilideATP-sensitive inward rectifier potassium channel 12target
DofetilideCytochrome P450 3A4enzyme
DofetilideSolute carrier family 22 member 2transporter
TorasemideSolute carrier family 12 member 1target
TorasemideCytochrome P450 2C8enzyme
TorasemideCytochrome P450 2C9enzyme
TorasemideSolute carrier organic anion transporter family member 1B1transporter
TorasemideSolute carrier family 12 member 2target
TorasemideSerum albumincarrier
GlimepirideATP-sensitive inward rectifier potassium channel 1target
GlimepirideATP-sensitive inward rectifier potassium channel 11target
GlimepirideCytochrome P450 2C9enzyme
GlimepirideATP-binding cassette sub-family C member 8target
GlimepirideBile salt export pumptransporter
MethyclothiazideSolute carrier family 12 member 1target
MethyclothiazideCarbonic anhydrase 4target
MethyclothiazideCarbonic anhydrase 2target
MethyclothiazideCarbonic anhydrase 1target
SulfanilamideDihydropteroate synthasetarget
SulfanilamideCytochrome P450 2C19enzyme
SulfanilamideCytochrome P450 2D6enzyme
SulfanilamideCytochrome P450 2E1enzyme
SulfanilamideCytochrome P450 3A4enzyme
SulfisoxazoleDihydropteroate synthasetarget
SulfisoxazoleCytochrome P450 2C9enzyme
IbutilidePotassium voltage-gated channel subfamily H member 6target
IbutilideVoltage-dependent L-type calcium channel subunit beta-1target
IbutilideVoltage-dependent calcium channel gamma-1 subunittarget
IbutilideVoltage-dependent calcium channel subunit alpha-2/delta-1target
IbutilidePotassium voltage-gated channel subfamily H member 2target
IbutilideVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
IbutilidePotassium channel subfamily K member 1target
IbutilidePotassium channel subfamily K member 6target
IbutilideATP-sensitive inward rectifier potassium channel 11target
IbutilidePotassium voltage-gated channel subfamily H member 7target
ChlorthalidoneSolute carrier family 12 member 1target
ChlorthalidoneSerum albumincarrier
ChlorthalidoneCarbonic anhydrase 1target
EthoxzolamideCarbonic anhydrase 1target
EthoxzolamideSolute carrier family 22 member 6transporter
EthoxzolamideCarbonic anhydrase 2target
EthoxzolamideCarbonic anhydrase 4target
EthoxzolamideCarbonic anhydrase 7target
EthoxzolamideCarbonic anhydrase 3target
SulfadiazineCytochrome P450 2C9enzyme
SulfadiazineDihydropteroate synthetasetarget
SulfadiazineCytochrome P450 2C8enzyme
SulfadiazineCytochrome P450 3A4enzyme
AcetohexamideATP-sensitive inward rectifier potassium channel 1target
AcetohexamideCarbonyl reductase [NADPH] 1enzyme
AcetohexamideSerum albumincarrier
AcetohexamideCytochrome P450 2C9enzyme
BendroflumethiazideSolute carrier family 12 member 3target
BendroflumethiazideCarbonic anhydrase 1target
BendroflumethiazideCarbonic anhydrase 2target
BendroflumethiazideCarbonic anhydrase 4target
BendroflumethiazideCalcium-activated potassium channel subunit alpha-1target
BendroflumethiazideThiopurine S-methyltransferaseenzyme
CelecoxibProstaglandin G/H synthase 2target
Celecoxib3-phosphoinositide-dependent protein kinase 1target
CelecoxibCytochrome P450 2C9enzyme
CelecoxibCytochrome P450 2D6enzyme
CelecoxibMultidrug resistance-associated protein 4transporter
CelecoxibCytochrome P450 3A4enzyme
CelecoxibCytochrome P450 2C8enzyme
CelecoxibCarbonic anhydrase 2target
CelecoxibCarbonic anhydrase 3target
CelecoxibBile salt export pumptransporter
CelecoxibCadherin-11target
CelecoxibP-glycoprotein 1transporter
CelecoxibATP-binding cassette sub-family G member 2transporter
MetolazoneSolute carrier family 12 member 3target
ZafirlukastCysteinyl leukotriene receptor 1target
ZafirlukastCytochrome P450 2C9enzyme
ZafirlukastCytochrome P450 2C8enzyme
ZafirlukastProstaglandin G/H synthase 1enzyme
ZafirlukastCytochrome P450 3A4enzyme
ZafirlukastCytochrome P450 1A2enzyme
ZafirlukastCytochrome P450 2C19enzyme
ZafirlukastCytochrome P450 2E1enzyme
ZafirlukastATP-binding cassette sub-family G member 2transporter
BosentanEndothelin B receptortarget
BosentanEndothelin-1 receptortarget
BosentanCytochrome P450 3A4enzyme
BosentanCytochrome P450 2C9enzyme
BosentanBile salt export pumptransporter
BenzthiazideSolute carrier family 12 member 3target
BenzthiazideCarbonic anhydrase 1target
BenzthiazideCarbonic anhydrase 2target
BenzthiazideCarbonic anhydrase 4target
BenzthiazideCarbonic anhydrase 9target
BenzthiazideCarbonic anhydrase 12target
BenzthiazideCarbonic anhydrasetarget
SulfamethizoleDihydropteroate synthasetarget
SulfamethizoleSerum albumincarrier
SulfamethizoleCytochrome P450 2C9enzyme
ValdecoxibProstaglandin G/H synthase 2target
ValdecoxibCytochrome P450 2C9enzyme
ValdecoxibCytochrome P450 3A4enzyme
ValdecoxibUDP-glucuronosyltransferase 1-9enzyme
ValdecoxibCarbonic anhydrase 2target
ValdecoxibCarbonic anhydrase 3target
CyclothiazideSodium/potassium-transporting ATPase subunit gammatarget
CyclothiazideCarbonic anhydrase 1target
CyclothiazideCarbonic anhydrase 2target
CyclothiazideSolute carrier family 22 member 6transporter
CyclothiazideSecreted frizzled-related protein 4target
CyclothiazideCarbonic anhydrasetarget
SulfacetamideDihydropteroate synthasetarget
SulfacetamideDihydropteroate synthase type-1target
SulfacetamideFolic acid synthesis protein FOL1target
SulfametopyrazineDihydropteroate synthetasetarget
Sumatriptan5-hydroxytryptamine receptor 1Dtarget
Sumatriptan5-hydroxytryptamine receptor 1Btarget
Sumatriptan5-hydroxytryptamine receptor 1Ftarget
SumatriptanAmine oxidase [flavin-containing] Aenzyme
Sumatriptan5-hydroxytryptamine receptor 1Atarget
SumatriptanSolute carrier organic anion transporter family member 1A2transporter
SumatriptanP-glycoprotein 1transporter
SumatriptanATP-binding cassette sub-family G member 2transporter
SumatriptanSolute carrier organic anion transporter family member 1B1transporter
ChlorpropamideATP-binding cassette sub-family C member 8target
ChlorpropamideSolute carrier family 15 member 1transporter
ChlorpropamideSolute carrier family 15 member 2transporter
ChlorpropamideSolute carrier family 22 member 6transporter
ChlorpropamideCytochrome P450 2C9enzyme
ChlorpropamideCytochrome P450 2C19enzyme
ChlorpropamideProstaglandin G/H synthase 1enzyme
FurosemideSolute carrier family 12 member 1target
FurosemideSerum albumincarrier
FurosemideSolute carrier family 22 member 6transporter
FurosemideSolute carrier family 22 member 5transporter
FurosemideSolute carrier family 22 member 8transporter
FurosemideCanalicular multispecific organic anion transporter 1transporter
FurosemideSolute carrier organic anion transporter family member 2A1transporter
FurosemideSolute carrier family 22 member 11transporter
Furosemide6-phosphogluconate dehydrogenase, decarboxylatingenzyme
FurosemideCarbonic anhydrase 2target
FurosemideUDP-glucuronosyltransferase 1-1enzyme
FurosemideThyroxine-binding globulincarrier
FurosemideG-protein coupled receptor 35target
AmprenavirHuman immunodeficiency virus type 1 proteasetarget
AmprenavirCytochrome P450 3A4enzyme
AmprenavirP-glycoprotein 1transporter
AmprenavirMultidrug resistance-associated protein 1transporter
AmprenavirCytochrome P450 2B6enzyme
AmprenavirCytochrome P450 2C19enzyme
AmprenavirCytochrome P450 2C9enzyme
AmprenavirCytochrome P450 2D6enzyme
AmprenavirCytochrome P450 3A5enzyme
AmprenavirSolute carrier organic anion transporter family member 1B1transporter
TamsulosinAlpha-1A adrenergic receptortarget
TamsulosinAlpha-1D adrenergic receptortarget
TamsulosinAlpha-1B adrenergic receptortarget
TamsulosinAlpha-1-acid glycoprotein 1carrier
TamsulosinCytochrome P450 2D6enzyme
TamsulosinCytochrome P450 3A4enzyme
HydroflumethiazideSolute carrier family 12 member 1target
HydroflumethiazideSodium/potassium-transporting ATPase subunit alpha-1target
HydroflumethiazideCarbonic anhydrase 4target
HydroflumethiazideCalcium-activated potassium channel subunit alpha-1target
HydroflumethiazideCarbonic anhydrase 2target
HydroflumethiazideCarbonic anhydrase 1target
HydroflumethiazideCarbonic anhydrase 9target
HydroflumethiazideCarbonic anhydrase 12target
HydroflumethiazideSerum albumincarrier
HydroflumethiazideSolute carrier family 22 member 6transporter
HydroflumethiazideSolute carrier family 22 member 8transporter
HydroflumethiazideCarbonic anhydrase 7target
SulfasalazineAcetyl-CoA acetyltransferase, mitochondrialtarget
SulfasalazineCystine/glutamate transportertarget
SulfasalazineATP-binding cassette sub-family G member 2transporter
SulfasalazineCanalicular multispecific organic anion transporter 1transporter
SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit betatarget
SulfasalazineProstaglandin G/H synthase 2target
SulfasalazinePeroxisome proliferator-activated receptor gammatarget
SulfasalazineProstaglandin G/H synthase 1target
SulfasalazineArachidonate 5-lipoxygenasetarget
SulfasalazineProton-coupled folate transportertransporter
SulfasalazineThromboxane-A synthasetarget
SulfasalazinePhospholipase A2target
SulfasalazineSolute carrier organic anion transporter family member 1B1transporter
SulfasalazineSolute carrier organic anion transporter family member 1B3transporter
SulfasalazineSolute carrier organic anion transporter family member 2B1transporter
IndapamideCytochrome P450 3A4enzyme
IndapamideSolute carrier family 12 member 3target
IndapamideEpoxide hydrolase 1enzyme
Indapamidealpha1-acid glycoproteincarrier
IndapamideSerum albumincarrier
IndapamideErythrocytecarrier
Sodium lauryl sulfateSerum albumincarrier
TolazamideSulfonylurea receptor 1, Kir6.2target
TolazamideCytochrome P450 2C9enzyme
DorzolamideCarbonic anhydrase 2target
DorzolamideCarbonic anhydrase 1target
DorzolamideCarbonic anhydrase 4target
DorzolamideCytochrome P450 2C9enzyme
DorzolamideCarbonic anhydrase 3target
DorzolamideCytochrome P450 2B1enzyme
DorzolamideCytochrome P450 2E1enzyme
DorzolamideCytochrome P450 3A2enzyme
ChlorothiazideSolute carrier family 12 member 3target
ChlorothiazideCarbonic anhydrase 1target
ChlorothiazideCarbonic anhydrase 2target
ChlorothiazideSolute carrier family 22 member 6transporter
BumetanideSolute carrier family 12 member 1target
BumetanideCystic fibrosis transmembrane conductance regulatortarget
BumetanideSolute carrier family 12 member 2target
BumetanideSolute carrier family 12 member 4target
BumetanideSolute carrier family 12 member 5target
BumetanideSodium/bile acid cotransportertransporter
BumetanideSolute carrier family 22 member 6transporter
BumetanideSolute carrier family 22 member 8transporter
BumetanideSolute carrier family 22 member 11transporter
BumetanideSolute carrier family 22 member 7transporter
BumetanideSolute carrier organic anion transporter family member 1A2transporter
BumetanideProstaglandin G/H synthase 2enzyme
SulfapyridineDihydropteroate synthase type-1target
SulfapyridineCytochrome P450 2C9enzyme
HydrochlorothiazideSolute carrier family 12 member 3target
HydrochlorothiazideSolute carrier family 22 member 6transporter
HydrochlorothiazideCalcium-activated potassium channel subunit alpha-1target
HydrochlorothiazideSerum albumincarrier
HydrochlorothiazideSolute carrier family 22 member 11transporter
HydrochlorothiazideMultidrug resistance-associated protein 4transporter
HydrochlorothiazideSolute carrier family 22 member 8transporter
SulfamethoxazoleCytochrome P450 2C9enzyme
SulfamethoxazoleSerum albumincarrier
SulfamethoxazoleArylamine N-acetyltransferase 1enzyme
SulfamethoxazoleArylamine N-acetyltransferase 2enzyme
SulfamethoxazoleDihydropteroate synthasetarget
SulfamethoxazoleCytochrome P450 3A4enzyme
SulfamethoxazoleBile salt export pumptransporter
GlyburideATP-binding cassette sub-family C member 9target
GlyburideBile salt export pumptarget
GlyburideATP-binding cassette sub-family A member 1target
GlyburideCystic fibrosis transmembrane conductance regulatortarget
GlyburideSulfonylurea receptor 1, Kir6.2target
GlyburideCytochrome P450 2C9enzyme
GlyburideCanalicular multispecific organic anion transporter 2transporter
GlyburideBile salt export pumptransporter
GlyburideP-glycoprotein 1transporter
GlyburideMultidrug resistance-associated protein 1transporter
GlyburideSolute carrier family 15 member 1transporter
GlyburideSolute carrier organic anion transporter family member 1A2transporter
GlyburideSolute carrier family 15 member 2transporter
GlyburideSolute carrier family 22 member 6transporter
GlyburideCanalicular multispecific organic anion transporter 1transporter
GlyburideATP-binding cassette sub-family G member 2transporter
GlyburideSolute carrier family 22 member 7transporter
GlyburideSolute carrier organic anion transporter family member 2B1transporter
GlyburideCytochrome P450 2C19enzyme
GlyburideCytochrome P450 3A4enzyme
GlyburideSerum albumincarrier
GlyburideMitochondrial ATP-sensitive potassium channeltarget
GlyburideCarnitine O-palmitoyltransferase 1, liver isoformtarget
GlyburideCytochrome P450 3A7enzyme
GlyburideCytochrome P450 3A5enzyme
GlyburideTransient receptor potential cation channel subfamily M member 4target
TrichlormethiazideSolute carrier family 12 member 3target
TrichlormethiazideSodium/potassium-transporting ATPase subunit alpha-1target
TrichlormethiazideCarbonic anhydrase 4target
TrichlormethiazideCarbonic anhydrase 2target
TrichlormethiazideCarbonic anhydrase 1target
TrichlormethiazideThiopurine S-methyltransferaseenzyme
ProbenecidSolute carrier family 22 member 8target
ProbenecidSolute carrier family 22 member 11target
ProbenecidSerum albumincarrier
ProbenecidSolute carrier family 22 member 2transporter
ProbenecidSolute carrier family 22 member 1transporter
ProbenecidCanalicular multispecific organic anion transporter 2transporter
ProbenecidMultidrug resistance-associated protein 4transporter
ProbenecidMultidrug resistance-associated protein 5transporter
ProbenecidMonocarboxylate transporter 2transporter
ProbenecidSolute carrier family 22 member 5transporter
ProbenecidMultidrug resistance-associated protein 6transporter
ProbenecidMultidrug resistance-associated protein 1transporter
ProbenecidSolute carrier organic anion transporter family member 1A2transporter
ProbenecidMonocarboxylate transporter 1transporter
ProbenecidSodium/bile acid cotransportertransporter
ProbenecidSolute carrier family 22 member 6transporter
ProbenecidSolute carrier family 22 member 10transporter
ProbenecidSolute carrier family 22 member 8transporter
ProbenecidCanalicular multispecific organic anion transporter 1transporter
ProbenecidATP-binding cassette sub-family C member 11transporter
ProbenecidSolute carrier family 22 member 11transporter
ProbenecidSolute carrier organic anion transporter family member 1C1transporter
ProbenecidSolute carrier family 22 member 7transporter
ProbenecidSolute carrier family 22 member 6target
ProbenecidPannexin-1target
ProbenecidCytochrome P450 2C8enzyme
ProbenecidCytochrome P450 3A4enzyme
ProbenecidSolute carrier family 22 member 12transporter
ProbenecidSolute carrier family 2, facilitated glucose transporter member 9transporter
ProbenecidTaste receptor type 2 member 16target
ProbenecidUDP-glucuronosyltransferase 1-1enzyme
ProbenecidCytochrome P450 2C9enzyme
GlipizideCytochrome P450 2C9enzyme
GlipizidePeroxisome proliferator-activated receptor gammatarget
GlipizideATP-binding cassette sub-family C member 8target
GlipizideUDP-glucuronosyltransferase 1-1enzyme
GlipizideBile salt export pumptransporter
GlipizideSerum albumincarrier
Rosuvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
RosuvastatinCytochrome P450 2C9enzyme
RosuvastatinMultidrug resistance-associated protein 4transporter
RosuvastatinSolute carrier organic anion transporter family member 1A2transporter
RosuvastatinSolute carrier organic anion transporter family member 1B3transporter
RosuvastatinSolute carrier organic anion transporter family member 2B1transporter
RosuvastatinCystine/glutamate transportertransporter
RosuvastatinSolute carrier organic anion transporter family member 1B1transporter
RosuvastatinBile salt export pumptransporter
RosuvastatinATP-binding cassette sub-family G member 2transporter
RosuvastatinSerum albumincarrier
RosuvastatinCanalicular multispecific organic anion transporter 1transporter
RosuvastatinSolute carrier family 22 member 8transporter
RosuvastatinSodium/bile acid cotransportertransporter
RosuvastatinIntegrin alpha-Ltarget
DiazoxideCarbonic anhydrase 1target
DiazoxideCarbonic anhydrase 2target
DiazoxideCalcium-activated potassium channel subunit alpha-1target
DiazoxideSodium/potassium-transporting ATPase subunit alpha-1target
DiazoxideATP-sensitive inward rectifier potassium channel 11target
DiazoxideGlutamine synthetaseenzyme
GliclazideATP-binding cassette sub-family C member 8target
GliclazideSerum albumincarrier
GliclazideVascular endothelial growth factor Atarget
GliclazideCytochrome P450 2C9enzyme
GliclazideCytochrome P450 2C19enzyme
TolbutamideATP-sensitive inward rectifier potassium channel 1target
TolbutamideCytochrome P450 2C19enzyme
TolbutamideCytochrome P450 2C9enzyme
TolbutamideCytochrome P450 2C8enzyme
TolbutamideATP-binding cassette sub-family C member 8target
TolbutamideSolute carrier family 15 member 1transporter
TolbutamideSolute carrier organic anion transporter family member 1A2transporter
TolbutamideSolute carrier family 15 member 2transporter
TolbutamideSolute carrier family 22 member 6transporter
TolbutamideSolute carrier organic anion transporter family member 2B1transporter
TolbutamideCytochrome P450 2C18enzyme
TolbutamideSerum albumincarrier
BicalutamideAndrogen receptortarget
BicalutamideCytochrome P450 3A4enzyme
BicalutamideCytochrome P450 2C19enzyme
BicalutamideCytochrome P450 2C9enzyme
BicalutamideCytochrome P450 2D6enzyme
BicalutamideP-glycoprotein 1transporter
DiclofenamideCarbonic anhydrase 1target
DiclofenamideCarbonic anhydrase 4target
DiclofenamideCarbonic anhydrase 2target
DiclofenamideCarbonic anhydrase 7target
DiclofenamideCarbonic anhydrase 3target
SulfoxoneDihydropteroate synthetasetarget
BrinzolamideCarbonic anhydrase 1target
BrinzolamideCarbonic anhydrase 2target
BrinzolamideCytochrome P450 3A4enzyme
BrinzolamideCarbonic anhydrase 5A, mitochondrialtarget
BrinzolamideCarbonic anhydrase 4target
BrinzolamideCarbonic anhydrase 3target
GliquidoneATP-binding cassette sub-family C member 8target
GliquidoneATP-sensitive inward rectifier potassium channel 8target
GliquidoneCytochrome P450 2C9enzyme
DarunavirHuman immunodeficiency virus type 1 proteasetarget
DarunavirCytochrome P450 3A4enzyme
DarunavirSolute carrier organic anion transporter family member 1B1transporter
DarunavirP-glycoprotein 1transporter
DarunavirSerum albumincarrier
DarunavirAlpha-1-acid glycoprotein 1carrier
DarunavirCytochrome P450 2D6enzyme
GlisoxepideATP-sensitive inward rectifier potassium channel 8target
GlisoxepideCytochrome P450 2C9enzyme
SulfacytineDihydropteroate synthasetarget
SulfadoxineDihydropteroate synthetasetarget
SulfadoxineBifunctional dihydrofolate reductase-thymidylate synthasetarget
FosamprenavirHuman immunodeficiency virus type 1 proteasetarget
FosamprenavirCytochrome P450 3A4enzyme
PolythiazideSolute carrier family 12 member 3target
PolythiazideSolute carrier family 22 member 6transporter
PolythiazideSolute carrier family 22 member 8transporter
PolythiazideSerum albumincarrier
QuinethazoneCarbonic anhydrase 1target
QuinethazoneCarbonic anhydrase 2target
QuinethazoneSolute carrier family 12 member 1target
QuinethazoneSolute carrier family 12 member 2target
QuinethazoneSolute carrier family 12 member 3target
GlymidineATP-sensitive inward rectifier potassium channel 1target
GlymidineATP-binding cassette sub-family C member 8target
SulfamerazineDihydropteroate synthasetarget
SulfamerazineSerum albumincarrier
SulfamethazineDihydropteroate synthasetarget
SulfamethazineSerum albumincarrier
SulfamethazineArylamine N-acetyltransferaseenzyme
SC-7402072 kDa type IV collagenasetarget
WAY-151693Collagenase 3target
DansylamideCarbonic anhydrase 2target
PiretanideSolute carrier family 12 member 1target
N,O-Didansyl-L-TyrosineThymidylate synthasetarget
N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideCalmodulintarget
N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideTroponin C, slow skeletal and cardiac musclestarget
N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideTroponin I, cardiac muscletarget
HydroxyfasudilRho-associated protein kinase 1target
HydroxyfasudilcAMP-dependent protein kinase catalytic subunit alphatarget
HydroxyfasudilcAMP-dependent protein kinase inhibitor alphatarget
NimesulideProstaglandin G/H synthase 2target
NimesulideGroup IIE secretory phospholipase A2target
NimesulideLactotransferrintarget
NimesulideCytochrome P450 3A4enzyme
BelinostatHistone deacetylasetarget
BelinostatCytochrome P450 1A2enzyme
BelinostatUDP-glucuronosyltransferase 1-4enzyme
BelinostatCytochrome P450 2C8enzyme
BelinostatCytochrome P450 2C9enzyme
BelinostatP-glycoprotein 1transporter
BelinostatCytochrome P450 3A4enzyme
INCB13739Corticosteroid 11-beta-dehydrogenase isozyme 1target
SLV319Cannabinoid receptor 1target
CimicoxibProstaglandin G/H synthase 2target
CimicoxibProstaglandin G/H synthase 2enzyme
KD3010Peroxisome proliferator-activated receptor deltatarget
XL765Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
XL765Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
XL765Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
XL765Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformtarget
XL765Serine/threonine-protein kinase mTORtarget
Silver sulfadiazineDNAtarget
Actelion-1Endothelin-1 receptortarget
AMG-131Peroxisome proliferator-activated receptor gammatarget
Naluzotan5-hydroxytryptamine receptor 1Atarget
ResatorvidCytokine receptor common subunit betatarget
ResatorvidCytokine receptor common subunit gammatarget
SulfathiazoleDihydropteroate synthetasetarget
SulfathiazoleCytochrome P450 19A1enzyme
SulfadimethoxineCytochrome P450 2C9enzyme
UdenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
UdenafilCytochrome P450 3A4enzyme
UdenafilCytochrome P450 3A5enzyme
SimeprevirNS3 proteasetarget
SimeprevirSerum albumincarrier
SimeprevirCytochrome P450 1A2enzyme
SimeprevirP-glycoprotein 1transporter
SimeprevirSolute carrier organic anion transporter family member 1B1transporter
SimeprevirSolute carrier organic anion transporter family member 1B3transporter
SimeprevirCytochrome P450 3A4enzyme
SimeprevirCanalicular multispecific organic anion transporter 1transporter
SimeprevirATP-binding cassette sub-family G member 2transporter
SimeprevirSolute carrier organic anion transporter family member 2B1transporter
SimeprevirSodium/bile acid cotransportertransporter
SimeprevirBile salt export pumptransporter
ElinogrelP2Y purinoceptor 12target
IndisulamCytochrome P450 2C9enzyme
IndisulamCytochrome P450 3A4enzyme
IndisulamCytochrome P450 2E1enzyme
IndisulamCytochrome P450 2D6enzyme
PazopanibVascular endothelial growth factor receptor 1target
PazopanibVascular endothelial growth factor receptor 2target
PazopanibVascular endothelial growth factor receptor 3target
PazopanibPlatelet-derived growth factor receptor alphatarget
PazopanibPlatelet-derived growth factor receptor betatarget
PazopanibMast/stem cell growth factor receptor Kittarget
PazopanibCytochrome P450 3A4enzyme
PazopanibCytochrome P450 2D6enzyme
PazopanibCytochrome P450 2C8enzyme
PazopanibCytochrome P450 1A2enzyme
PazopanibP-glycoprotein 1transporter
PazopanibATP-binding cassette sub-family G member 2transporter
PazopanibSolute carrier organic anion transporter family member 1B1transporter
PazopanibUDP-glucuronosyltransferase 1-1transporter
PazopanibFibroblast growth factor receptor 3target
PazopanibTyrosine-protein kinase ITK/TSKtarget
PazopanibFibroblast growth factor 1target
PazopanibSH2B adapter protein 3target
ClazosentanEndothelin-1 receptortarget
SulfaphenazoleCytochrome P450 2C9enzyme
SulfaphenazoleCytochrome P450 2B6enzyme
SulfaphenazoleCytochrome P450 2C8enzyme
SulfaphenazoleCytochrome P450 2D6enzyme
SulfaphenazoleDihydropteroate synthasetarget
MafenideCarbonic anhydrase 6target
SulfameterDihydropteroate synthasetarget
TO-901317Oxysterols receptor LXR-betatarget
TO-901317Nuclear receptor coactivator 2target
TO-901317Retinoic acid receptor RXR-betatarget
TO-901317Oxysterols receptor LXR-alphatarget
TO-901317Nuclear receptor coactivator 1target
TO-901317Nuclear receptor subfamily 1 group I member 2target
5-(2-methylpiperazine-1-sulfonyl)isoquinolinecAMP-dependent protein kinase catalytic subunit alphatarget
5-(2-methylpiperazine-1-sulfonyl)isoquinolinecAMP-dependent protein kinase inhibitor alphatarget
4-(2-AMINOETHYL)BENZENESULFONAMIDECarbonic anhydrase 2target
SulfamoxoleDihydropteroate synthetasetarget
SulfamoxoleCytochrome P450 2C9enzyme
VemurafenibSerum albumincarrier
VemurafenibAlpha-1-acid glycoprotein 1carrier
VemurafenibCytochrome P450 1A2enzyme
VemurafenibCytochrome P450 2D6enzyme
VemurafenibCytochrome P450 3A4enzyme
VemurafenibSerine/threonine-protein kinase B-raftarget
VemurafenibMultidrug resistance-associated protein 1transporter
VemurafenibATP-binding cassette sub-family G member 2transporter
VemurafenibCytochrome P450 2C9enzyme
VemurafenibCytochrome P450 2C8enzyme
VemurafenibCytochrome P450 2B6enzyme
VemurafenibP-glycoprotein 1transporter
MacitentanCytochrome P450 3A4enzyme
MacitentanCytochrome P450 2C19enzyme
MacitentanEndothelin-1 receptortarget
MacitentanEndothelin B receptortarget
MacitentanSerum albumincarrier
GlibornurideCytochrome P450 2C9enzyme
BlinatumomabB-lymphocyte antigen CD19target
BlinatumomabT-cell surface glycoprotein CD3 delta chaintarget
DasabuvirNonstructural protein 5B (NS5B)target
DasabuvirCytochrome P450 2C8enzyme
DasabuvirCytochrome P450 3A4enzyme
DasabuvirCytochrome P450 2D6enzyme
DasabuvirUDP-glucuronosyltransferase 1-4enzyme
DasabuvirATP-binding cassette sub-family G member 2transporter
DasabuvirATP-binding cassette sub-family B member 5transporter
DasabuvirP-glycoprotein 1transporter
AsunaprevirGenome polyproteintarget
AsunaprevirCytochrome P450 3A4enzyme
AsunaprevirCytochrome P450 3A5enzyme
AsunaprevirCytochrome P450 2A6enzyme
AsunaprevirCytochrome P450 2B6enzyme
AsunaprevirCytochrome P450 2C9enzyme
AsunaprevirCytochrome P450 2C19enzyme
AsunaprevirCytochrome P450 2D6enzyme
AsunaprevirSolute carrier organic anion transporter family member 1B1transporter
AsunaprevirSolute carrier organic anion transporter family member 1B3transporter
AsunaprevirSolute carrier organic anion transporter family member 2B1transporter
AsunaprevirP-glycoprotein 1transporter
PavinetantNeuromedin-K receptortarget
EncorafenibCytochrome P450 3A4enzyme
EncorafenibCytochrome P450 2C19enzyme
EncorafenibCytochrome P450 2D6enzyme
EncorafenibSerine/threonine-protein kinase B-raftarget
EncorafenibG1/S-specific cyclin-D1target
PilaralisibPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
DanoprevirGenome polyproteintarget
DanoprevirCytochrome P450 3A4enzyme
MirodenafilCytochrome P450 3A Subfamilyenzyme
BaricitinibSolute carrier family 22 member 8transporter
BaricitinibATP-binding cassette sub-family G member 2transporter
BaricitinibMultidrug and toxin extrusion protein 2transporter
BaricitinibCytochrome P450 3A4enzyme
BaricitinibTyrosine-protein kinase JAK1target
BaricitinibTyrosine-protein kinase JAK2target
BaricitinibSolute carrier family 22 member 6transporter
BaricitinibSolute carrier family 22 member 2transporter
BaricitinibSolute carrier organic anion transporter family member 1B3transporter
BaricitinibProtein-tyrosine kinase 2-betatarget
BaricitinibTyrosine-protein kinase JAK3target
BaricitinibP-glycoprotein 1transporter
NavitoclaxApoptosis regulator Bcl-2target
NavitoclaxBcl-2-like protein 2target
NavitoclaxBcl2 antagonist of cell deathtarget
FedratinibP-glycoprotein 1transporter
FedratinibATP-binding cassette sub-family G member 2transporter
FedratinibSolute carrier organic anion transporter family member 1B1transporter
FedratinibSolute carrier organic anion transporter family member 1B3transporter
FedratinibPOU domain, class 2, transcription factor 2transporter
FedratinibMultidrug and toxin extrusion protein 1transporter
FedratinibMultidrug and toxin extrusion protein 2transporter
FedratinibCytochrome P450 3A4enzyme
FedratinibCytochrome P450 2C19enzyme
FedratinibDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
FedratinibTyrosine-protein kinase JAK2target
FedratinibReceptor-type tyrosine-protein kinase FLT3target
FedratinibTyrosine-protein kinase JAK1target
FedratinibCytochrome P450 2D6enzyme
GrapiprantProstaglandin E2 receptor EP4 subtypetarget
GrapiprantP-glycoprotein 1transporter
GrapiprantSerum albumincarrier
RamatrobanProstaglandin D2 receptor 2target
RipasudilRho-associated protein kinase 1target
RipasudilRho-associated protein kinase 2target
CarbutamideCytochrome P450 2C9enzyme
MetahexamideCytochrome P450 2C9enzyme
SB-2699705-hydroxytryptamine receptor 7target
Acetyl sulfisoxazoleDihydropteroate synthasetarget
Acetyl sulfisoxazoleCytochrome P450 2C9enzyme
SC-236Cyclooxygenase 2target
SC-236Nuclear factor NF-kappa-B complextarget
NS-398Cyclooxygenase 2target
NesbuvirGenome polyproteintarget
NesbuvirGenome polyproteintarget
FasudilcAMP-dependent protein kinase inhibitor alphatarget
FasudilcAMP-dependent protein kinase catalytic subunit alphatarget
FasudilRho-associated protein kinase 1target
FasudilRho-associated protein kinase 2target
VenetoclaxApoptosis regulator Bcl-2target
VenetoclaxCytochrome P450 3A4enzyme
VenetoclaxP-glycoprotein 1transporter
VenetoclaxATP-binding cassette sub-family G member 2transporter
VenetoclaxSolute carrier organic anion transporter family member 1B1transporter
VercirnonC-C chemokine receptor type 9target
ZonisamideSodium channel protein type 1 subunit alphatarget
ZonisamideCarbonic anhydrase 1target
ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
ZonisamideCytochrome P450 3A4enzyme
ZonisamideAldehyde oxidaseenzyme
ZonisamideAmine oxidase [flavin-containing] Btarget
ZonisamideCarbonic anhydrase 2target
ZonisamideCarbonic anhydrase 3target
ZonisamideCarbonic anhydrase 4target
ZonisamideCarbonic anhydrase 5A, mitochondrialtarget
ZonisamideCarbonic anhydrase 5B, mitochondrialtarget
ZonisamideCarbonic anhydrase 6target
ZonisamideCarbonic anhydrase 7target
ZonisamideCarbonic anhydrase-related proteintarget
ZonisamideCarbonic anhydrase 9target
ZonisamideCarbonic anhydrase-related protein 10target
ZonisamideCarbonic anhydrase-related protein 11target
ZonisamideCarbonic anhydrase 12target
ZonisamideCarbonic anhydrase 13target
ZonisamideCarbonic anhydrase 14target
ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Htarget
ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Itarget
ZonisamideSodium channel protein type 2 subunit alphatarget
ZonisamideSodium channel protein type 3 subunit alphatarget
ZonisamideSodium channel protein type 4 subunit alphatarget
ZonisamideSodium channel protein type 5 subunit alphatarget
ZonisamideSodium channel protein type 9 subunit alphatarget
ZonisamideSodium channel protein type 11 subunit alphatarget
ZonisamideSodium channel subunit beta-1target
ZonisamideSodium channel subunit beta-2target
ZonisamideSodium channel subunit beta-3target
ZonisamideSodium channel subunit beta-4target
ZonisamideAmine oxidase [flavin-containing] Atarget
ZonisamideCytochrome P450 2C19enzyme
ZonisamideUDP-glucuronosyltransferase 1-1enzyme
ZonisamideCytochrome P450 3A5enzyme
ZonisamideP-glycoprotein 1transporter
TazobactamBeta-lactamase TEMtarget
TazobactamSolute carrier family 22 member 6transporter
TazobactamSolute carrier family 22 member 8transporter
TazobactamBeta-lactamase Ohio-1target
TazobactamBeta-lactamase SHV-1target
EtoricoxibProstaglandin G/H synthase 2target
EtoricoxibCytochrome P450 3A4enzyme
EtoricoxibCytochrome P450 2C9enzyme
EtoricoxibCytochrome P450 2D6enzyme
EtoricoxibCytochrome P450 1A2enzyme
EtoricoxibCytochrome P450 2C19enzyme
EtoricoxibCytochrome P450 2E1enzyme
VoxilaprevirCytochrome P450 3A4enzyme
VoxilaprevirCytochrome P450 1A2enzyme
VoxilaprevirCytochrome P450 2C8enzyme
VoxilaprevirNS3/4A proteintarget
VoxilaprevirP-glycoprotein 1transporter
VoxilaprevirATP-binding cassette sub-family G member 2transporter
VoxilaprevirSolute carrier organic anion transporter family member 1B1transporter
VoxilaprevirSolute carrier organic anion transporter family member 1B3transporter
GlecaprevirCytochrome P450 3A Subfamilyenzyme
GlecaprevirUDP-glucuronosyltransferase 1-1enzyme
GlecaprevirP-glycoprotein 1transporter
GlecaprevirATP-binding cassette sub-family G member 2transporter
GlecaprevirSolute carrier organic anion transporter family member 1B1transporter
GlecaprevirSolute carrier organic anion transporter family member 1B3transporter
GlecaprevirNS3 proteasetarget
GlecaprevirCytochrome P450 3A4enzyme
PLX-4720Serine/threonine-protein kinase B-raftarget
GW-813893Prothrombintarget
GW-813893Coagulation factor Xtarget
CGS-27023Macrophage metalloelastasetarget
CGS-27023Interstitial collagenasetarget
H-89cAMP-dependent protein kinase catalytic subunit alphatarget
H-89cAMP-dependent protein kinase inhibitor alphatarget
H-89Serine/threonine-protein kinase haspintarget