Allergic Rhinitis (AR)

Also known as: Rhinitis,Allergic / Rhinitis, Allergic / Allergic rhinitis / Rhinitis Allergic / Allergic rhinitis, cause unspecified / Allergic rhinitis, unspecified / Rhinallergosis / Rhinitis allergic NOS / Hay fever

DrugDrug NameDrug Description
DB00835BrompheniramineA histamine H1 antagonist used to treat coughs, upper respiratory symptoms, and nasal congestion associated with allergies and the common cold.
DB01222BudesonideA corticosteroid used in the management of asthma, nasal polyposis, and rhinitis via inhalation, as well as mild to moderate active Crohn's disease and ulcerative colitis via ingestion.
DB00748CarbinoxamineA first generation antihistamine used to treat allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, allergic reactions, and mild allergic reactions.
DB08936ChlorcyclizineChlorcyclizine is a first generation phenylpiperazine class antihistamine used to treat urticaria, rhinitis, pruritus, and other allergy symptoms. Chlorcyclizine also has some local anesthetic, anticholinergic, and antiserotonergic properties, and can...
DB01114ChlorpheniramineA histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies.
DB00283ClemastineAn antihistamine with sedative and anticholinergic effects used to treat the symptoms of allergic rhinitis.
DB00405DexbrompheniramineAn antihistamine used to treat allergy symptoms including upper respiratory tract symptoms.
DB09555Dexchlorpheniramine maleateA first generation antihistamine used to treat allergic and vasomotor rhinitis, allergic conjunctivitis, and mild urticaria and angioedema.
DB01075DiphenhydramineA H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes.
DB01146DiphenylpyralineAn antihistamine used for the treatment of allergic rhinitis, hay fever, and allergic skin disorders.
DB00180FlunisolideAn inhaled corticosteroid used as a prophylactic therapy in the maintenance treatment of asthma.
DB00588Fluticasone propionateA glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis.
DB00741HydrocortisoneA glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
DB01106LevocabastineA selective histamine H1 receptor antagonist indicated for the management of seasonal allergic conjunctivitis symptoms.
DB06691MepyramineAn antihistamine agent used for the symptomatic treatment of allergy, hypersensitivity reactions, and pruritic skin disorders.
DB00764MometasoneA corticosteroid used to treat asthma and allergic rhinitis.
DB14512Mometasone furoateA corticosteroid used to treat asthma, allergic rhinitis, nasal congestion, nasal polyps, dermatitis, and pruritus.
DB00635PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
DB11614RupatadineA selective histamine H1 receptor antagonist and platelet activating factor (PAF) antagonist used to treat allergic rhinitis.
DB00620TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
DrugDrug NameTargetType
DB00835BrompheniramineHistamine H1 receptortarget
DB00835BrompheniramineMuscarinic acetylcholine receptor M1target
DB00835BrompheniramineMuscarinic acetylcholine receptor M2target
DB00835BrompheniramineMuscarinic acetylcholine receptor M3target
DB00835BrompheniramineMuscarinic acetylcholine receptor M4target
DB00835BrompheniramineMuscarinic acetylcholine receptor M5target
DB01222BudesonideGlucocorticoid receptortarget
DB01222BudesonideCytochrome P450 3A4enzyme
DB01222BudesonideCytochrome P450 3A5enzyme
DB01222BudesonideBile salt export pumptransporter
DB01222BudesonideP-glycoprotein 1transporter
DB00748CarbinoxamineHistamine H1 receptortarget
DB08936ChlorcyclizineHistamine H1 receptortarget
DB01114ChlorpheniramineHistamine H1 receptortarget
DB01114ChlorpheniramineCytochrome P450 3A4enzyme
DB01114ChlorpheniramineCytochrome P450 2D6enzyme
DB01114ChlorpheniramineSodium-dependent serotonin transportertarget
DB01114ChlorpheniramineSodium-dependent noradrenaline transportertarget
DB01114ChlorpheniramineSodium-dependent dopamine transportertarget
DB01114ChlorpheniramineCytochrome P450 3A5enzyme
DB01114ChlorpheniramineCytochrome P450 3A7enzyme
DB01114ChlorpheniramineSolute carrier family 22 member 2transporter
DB01114ChlorpheniramineSolute carrier family 22 member 1transporter
DB00283ClemastineHistamine H1 receptortarget
DB00283ClemastineCytochrome P450 2D6enzyme
DB00405DexbrompheniramineHistamine H1 receptortarget
DB09555Dexchlorpheniramine maleateCytochrome P450 2D6enzyme
DB09555Dexchlorpheniramine maleateHistamine H1 receptortarget
DB09555Dexchlorpheniramine maleateSolute carrier family 22 member 1carrier
DB09555Dexchlorpheniramine maleateSolute carrier family 22 member 2carrier
DB09555Dexchlorpheniramine maleateCytochrome P450 3A4enzyme
DB01075DiphenhydramineHistamine H1 receptortarget
DB01075DiphenhydramineCytochrome P450 2D6enzyme
DB01075DiphenhydramineCytochrome P450 2C9enzyme
DB01075DiphenhydramineCytochrome P450 2C19enzyme
DB01075DiphenhydramineSolute carrier family 22 member 2transporter
DB01075DiphenhydramineSolute carrier family 22 member 5transporter
DB01075DiphenhydramineProstaglandin G/H synthase 1enzyme
DB01075DiphenhydramineMuscarinic acetylcholine receptor M2target
DB01146DiphenylpyralineHistamine H1 receptortarget
DB01146DiphenylpyralineSodium-dependent dopamine transportertarget
DB00180FlunisolideCorticosteroid-binding globulincarrier
DB00180FlunisolideGlucocorticoid receptortarget
DB00180FlunisolideCytochrome P450 3A4enzyme
DB00588Fluticasone propionateCorticosteroid-binding globulincarrier
DB00588Fluticasone propionateCytosolic phospholipase A2target
DB00588Fluticasone propionateGlucocorticoid receptortarget
DB00588Fluticasone propionateCytochrome P450 3A4enzyme
DB00588Fluticasone propionateProgesterone receptortarget
DB00588Fluticasone propionateMineralocorticoid receptortarget
DB00588Fluticasone propionateCytochrome P450 3A5enzyme
DB00588Fluticasone propionateCytochrome P450 3A7enzyme
DB00588Fluticasone propionateCytochrome P450 2C8enzyme
DB00588Fluticasone propionateP-glycoprotein 1carrier
DB00588Fluticasone propionateSolute carrier organic anion transporter family member 1B1carrier
DB00741HydrocortisoneAnnexin A1target
DB00741HydrocortisoneGlucocorticoid receptortarget
DB00741HydrocortisoneSex hormone-binding globulincarrier
DB00741HydrocortisoneCytochrome P450 3A4enzyme
DB00741HydrocortisoneCytochrome P450 3A5enzyme
DB00741HydrocortisoneCytochrome P450 3A7enzyme
DB00741HydrocortisoneP-glycoprotein 1transporter
DB00741HydrocortisoneSolute carrier organic anion transporter family member 1A2transporter
DB00741HydrocortisoneCytochrome P450 11B1, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 11B2, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 2C8enzyme
DB00741HydrocortisoneCorticosteroid-binding globulincarrier
DB00741HydrocortisoneSolute carrier family 22 member 8transporter
DB00741Hydrocortisone3-oxo-5-beta-steroid 4-dehydrogenaseenzyme
DB00741Hydrocortisone3-oxo-5-alpha-steroid 4-dehydrogenase 2enzyme
DB00741HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DB00741HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB00741HydrocortisoneCytochrome P450 2A6enzyme
DB00741HydrocortisoneCytochrome P450 1B1enzyme
DB00741HydrocortisoneCytochrome P450 2B6enzyme
DB00741HydrocortisoneCytochrome P450 2C9enzyme
DB00741HydrocortisoneCytochrome P450 2C19enzyme
DB00741HydrocortisoneP-glycoprotein 1enzyme
DB01106LevocabastineNeurotensin receptor type 2target
DB01106LevocabastineHistamine H1 receptortarget
DB06691MepyramineCytochrome P450 2D6enzyme
DB06691MepyramineHistamine H1 receptortarget
DB06691MepyramineSolute carrier family 22 member 4transporter
DB06691MepyramineSolute carrier family 22 member 5transporter
DB00764MometasoneGlucocorticoid receptortarget
DB00764MometasoneCytochrome P450 2C8enzyme
DB00764MometasoneProgesterone receptortarget
DB00764MometasoneCytochrome P450 3A4enzyme
DB00764MometasoneCytochrome P450 3A5enzyme
DB14512Mometasone furoateGlucocorticoid receptortarget
DB14512Mometasone furoateCytochrome P450 2C8enzyme
DB14512Mometasone furoateProgesterone receptortarget
DB14512Mometasone furoateCytochrome P450 3A4enzyme
DB14512Mometasone furoateCytochrome P450 3A5enzyme
DB00635PrednisoneGlucocorticoid receptortarget
DB00635PrednisoneCytochrome P450 3A4enzyme
DB00635PrednisoneP-glycoprotein 1transporter
DB00635PrednisoneSolute carrier organic anion transporter family member 1A2transporter
DB00635PrednisoneCytochrome P450 2C19enzyme
DB00635PrednisoneSerum albumincarrier
DB00635PrednisoneCytochrome P450 3A5enzyme
DB00635PrednisoneCorticosteroid-binding globulincarrier
DB00635PrednisoneCytochrome P450 3A Subfamilyenzyme
DB00635PrednisoneCytochrome P450 2A6enzyme
DB00635PrednisoneCytochrome P450 1B1enzyme
DB00635PrednisoneCytochrome P450 2B6enzyme
DB00635PrednisoneCytochrome P450 2C8enzyme
DB00635PrednisoneCytochrome P450 2C9enzyme
DB00635PrednisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB11614RupatadineCytochrome P450 3A4enzyme
DB11614RupatadineCytochrome P450 2C9enzyme
DB11614RupatadineCytochrome P450 2C19enzyme
DB11614RupatadineCytochrome P450 2D6enzyme
DB11614RupatadinePlatelet-activating factor receptortarget
DB11614RupatadineHistamine H1 receptortarget
DB00620TriamcinoloneCorticosteroid-binding globulincarrier
DB00620TriamcinoloneGlucocorticoid receptortarget
DB00620TriamcinoloneCytochrome P450 3A4enzyme
DB00620TriamcinoloneProstaglandin G/H synthase 2enzyme
DB00620TriamcinoloneCholinesteraseenzyme
DB00620TriamcinoloneCytochrome P450 3A5enzyme
DB00620TriamcinoloneCytochrome P450 3A7enzyme
DB00620TriamcinoloneSerum albumincarrier
DrugDrug NamePhaseStatusCount
DB01222Budesonide0Completed1
DB00471Montelukast0Completed1
DB14868AZD-88481Completed2
DB00972Azelastine1Completed2
DB04890Bepotastine1Completed1
DB01410Ciclesonide1Completed1
DB01075Diphenhydramine1Completed1
DB00366Doxylamine1Completed1
DB11823Esketamine1Completed1
DB13867Fluticasone1Completed2
DB00588Fluticasone propionate1Completed4
DB12806GSK-10047231Completed1
DB05381Histamine1Completed1
DB11320Histamine1Completed1
DB01050Ibuprofen1Completed1
DB09054Idelalisib1Completed1
DB00465Ketorolac1Completed1
DB00764Mometasone1Completed2
DB00043Omalizumab1Completed1
DB00935Oxymetazoline1Completed2
DB00635Prednisone1Completed1
DB15176Quilizumab1Completed1
DB00163Vitamin E1Completed1
DB04890Bepotastine1 / 2Completed1
DB05381Histamine1 / 2Unknown Status1
DB14868AZD-88482Completed1
DB00972Azelastine2Completed2
DB01222Budesonide2Completed1
DB00341Cetirizine2Completed3
DB01114Chlorpheniramine2Terminated1
DB14789Dectrekumab2Completed1
DB12159Dupilumab2Completed1
DB00751Epinastine2Completed1
DB12011Fevipiprant2Completed1
DB00950Fexofenadine2Completed2
DB13867Fluticasone2Completed1
DB00588Fluticasone propionate2Completed3
DB12806GSK-10047232Completed1
DB12137GSK-2560662Completed2
DB11650HT-07122Completed1
DB12929JNJ-392206752Completed1
DB06282Levocetirizine2Completed1
DB00455Loratadine2Completed3
DB00471Montelukast2Completed2
DB11900OC-4592Completed2
DB00768Olopatadine2Completed1
DB00935Oxymetazoline2Completed1
DB12201PF-036547462Completed1
DB12360PF-036547642Completed1
DB00852Pseudoephedrine2Completed3
DB11658QAV-6802Completed1
DB00277Theophylline2Completed1
DB00062Albumin human2 / 3Completed2
DB00972Azelastine3Completed1
DB00972Azelastine3Recruiting1
DB00394Beclomethasone dipropionate3Completed3
DB00443Betamethasone3Completed1
DB00443Betamethasone3Unknown Status1
DB01222Budesonide3Completed2
DB00341Cetirizine3Completed2
DB01410Ciclesonide3Completed4
DB00967Desloratadine3Completed5
DB00967Desloratadine3Unknown Status1
DB13679Dexchlorpheniramine3Completed1
DB13679Dexchlorpheniramine3Unknown Status1
DB08906Fluticasone furoate3Completed1
DB00588Fluticasone propionate3Completed4
DB00588Fluticasone propionate3Recruiting1
DB06282Levocetirizine3Completed4
DB00455Loratadine3Completed2
DB00455Loratadine3Withdrawn1
DB00764Mometasone3Not Yet Recruiting2
DB14512Mometasone furoate3Completed5
DB14512Mometasone furoate3Not Yet Recruiting2
DB00471Montelukast3Completed2
DB00860Prednisolone3Completed1
DB00860Prednisolone3Unknown Status1
DB00852Pseudoephedrine3Withdrawn1
DB00620Triamcinolone3Completed1
DB00972Azelastine4Completed2
DB00972Azelastine4Recruiting2
DB00972Azelastine4Terminated1
DB00972Azelastine4Withdrawn1
DB00394Beclomethasone dipropionate4Completed1
DB11591Bilastine4Completed2
DB01222Budesonide4Completed1
DB06774Capsaicin4Unknown Status1
DB00341Cetirizine4Completed4
DB00341Cetirizine4Recruiting1
DB01410Ciclesonide4Completed2
DB00967Desloratadine4Completed1
DB00590Doxazosin4Completed1
DB00950Fexofenadine4Completed6
DB13867Fluticasone4Completed2
DB13867Fluticasone4Withdrawn1
DB08906Fluticasone furoate4Completed2
DB08906Fluticasone furoate4Withdrawn1
DB00588Fluticasone propionate4Completed7
DB00588Fluticasone propionate4Recruiting2
DB00588Fluticasone propionate4Terminated1
DB00588Fluticasone propionate4Withdrawn2
DB06282Levocetirizine4Completed6
DB00455Loratadine4Completed3
DB00455Loratadine4Not Yet Recruiting1
DB00764Mometasone4Completed1
DB14512Mometasone furoate4Completed4
DB00471Montelukast4Completed5
DB00768Olopatadine4Completed1
DB00768Olopatadine4Withdrawn1
DB00043Omalizumab4Completed1
DB00935Oxymetazoline4Completed2
DB00935Oxymetazoline4Withdrawn1
DB00457Prazosin4Completed1
DB00852Pseudoephedrine4Completed1
DB02709Resveratrol4Completed1
DB00938Salmeterol4Completed1
DB01390Sodium bicarbonate4Completed1
DB00277Theophylline4Completed1
DB11897Beclomethasone dipropionateNot AvailableCompleted1
DB00394Beclomethasone dipropionateNot AvailableUnknown Status1
DB01222BudesonideNot AvailableCompleted1
DB01222BudesonideNot AvailableUnknown Status1
DB13867FluticasoneNot AvailableCompleted1
DB08906Fluticasone furoateNot AvailableCompleted1
DB00983FormoterolNot AvailableUnknown Status1
DB05381HistamineNot AvailableCompleted2
DB11320HistamineNot AvailableCompleted1
DB11858Leukotriene D4Not AvailableCompleted1
DB06282LevocetirizineNot AvailableCompleted1
DB06709MethacholineNot AvailableCompleted1
DB14512Mometasone furoateNot AvailableCompleted1
DB00768OlopatadineNot AvailableCompleted1
DB00043OmalizumabNot AvailableCompleted1
DB00043OmalizumabNot AvailableUnknown Status1