Serotonin Agents

Drugs used for their effects on serotonergic systems. Among these are drugs that affect serotonin receptors, the life cycle of serotonin, and the survival of serotonergic neurons.
DrugDrug NameDrug Indication
DB00176FluvoxamineFor management of depression and for Obsessive Compulsive Disorder (OCD). Has also been used in the management of bulimia nervosa.
DB00215CitalopramFor the treatment of depression. Unlabeled indications include: treatment of mild dementia-associated agitation in nonpsychotic patients, smoking cessation, ethanol abuse, obsessive-compulsive disorder (OCD) in children, and diabetic neuropathy.
DB00216EletriptanFor the acute treatment of migraine with or without aura in adults.
DB00246ZiprasidoneFor the treatment of schizophrenia and related psychotic disorders.
DB00247MethysergideFor the treatment of vascular headache
DB00315ZolmitriptanFor the acute treatment of adult migraine with or without auras.
DB00334OlanzapineFor the acute and maintenance treatment of schizophrenia and related psychotic disorders, as well as acute treatment of manic or mixed episodes of bipolar 1 disorder. Intramuscular olanzapine is indicated for the rapid control of agitated patients.
DB00363ClozapineFor use in patients with treatment-resistant schizophrenia.
DB00377PalonosetronFor the prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of moderately emetogenic cancer chemotherapy, as well as prevention of acute nausea and vomiting associated with highly emetogenic cancer chemotherapy. Also used for the prevention of postoperative nausea and vomiting for up to 24 hours post operation.
DB00434CyproheptadineFor treatment of perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis due to inhalant allergens and foods, mild uncomplicated allergic skin manifestations of urticaria and angioedema, amelioration of allergic reactions to blood or plasma, cold urticaria, dermatographism, and as therapy for anaphylactic reactions adjunctive to epinephrine.
DB00472FluoxetineLabeled indication include: major depressive disorder (MDD), moderate to severe bulimia nervosa, obsessive-compulsive disorder (OCD), premenstrual dysphoric disorder (PMDD), panic disorder with or without agoraphobia, and combination treatment with olanzapine for treatment-resistant or bipolar I depression. Unlabeled indications include: selective mutism, mild dementia-associated agitation in nonpsychotic patients, post-traumatic stress disorder (PTSD), social anxiety disorder, chronic neuropathic pain, fibromyalgia, and Raynaud's phenomenon.
DB00490BuspironeFor the management of anxiety disorders or the short-term relief of the symptoms of anxiety, and also as an augmention of SSRI-treatment against depression.
DB00543AmoxapineFor the relief of symptoms of depression in patients with neurotic or reactive depressive disorders as well as endogenous and psychotic depressions. May also be used to treat depression accompanied by anxiety or agitation.
DB00574FenfluramineFor the management of exogenous obesity as a short-term (a few weeks) adjunct in a regimen of weight reduction based on caloric restriction.
DB00589LisurideFor the management of Parkinson's Disease
DB00604CisaprideFor the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease.
DB00656TrazodoneFor the treatment of depression.
DB00669SumatriptanFor the treatment of migraine attacks with or without aura.
DB00696ErgotamineFor use as therapy to abort or prevent vascular headache, e.g., migraine, migraine variants, or so called "histaminic cephalalgia".
DB00715ParoxetineLabeled indications include: major depressive disorder (MDD), panic disorder with or without agoraphobia, obsessive-compulsive disorder (OCD), social anxiety disorder (social phobia), generalized anxiety disorder (GAD), post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD). Unlabeled indications include: eating disorders, impulse control disorders, vasomotor symptoms of menopause, obsessive-compulsive disorder (OCD) in children, and mild dementia-associated agitation in nonpsychotic individuals. Brisdelle, which consists of paroxetine mesylate is indicated for the treatment of moderate to severe vasomotor symptoms (like hot flashes) associated with menopause.
DB00734RisperidoneFor the treatment of schizophrenia in adults and in adolescents, ages 13 to 17, and for the short-term treatment of manic or mixed episodes of bipolar I disorder in children and adolescents ages 10 to 17. May also be used to manage symptoms of inappropriate behavior due to aggression and/or psychosis in patients with severe dementia.
DB00757DolasetronFor the prevention of nausea and vomiting associated with emetogenic cancer chemotherapy, including initial and repeat courses of chemotherapy. Also used for the prevention of postoperative nausea and vomiting. This drug can be used intravenously for the treatment of postoperative nausea and vomiting.
DB00889GranisetronFor the prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer therapy (including high dose cisplatin), postoperation, and radiation (including total body irradiation and daily fractionated abdominal radiation).
DB00904OndansetronFor the prevention of nausea and vomiting associated with emetogenic cancer chemotherapy, postoperation, and radiation. Also used for the treatment of postoperative nausea and vomiting.
DB00918AlmotriptanFor the treatment of acute migraine headache in adults
DB00952NaratriptanFor the acute treatment of migraine attacks with or without aura in adults.
DB00953RizatriptanFor treatment of acute migraine attacks with or without aura.
DB00960PindololFor the management of hypertension, edema, ventricular tachycardias, and atrial fibrillation.
DB00969AlosetronOnly for the treatment of symptoms of severe diarrhea-predominant irritable bowel syndrome (IBS) in women with chronic symptoms (generally lasting greater than 6 months) who does not present with anatomic or biochemical GI abnormalities and have not responded to conventional therapy.
DB00998FrovatriptanFor the acute treatment of migraine attacks with or without aura in adults.
DB01079TegaserodProvides relief from the symptoms of irritable bowel syndrome including chronic idiopathic constipation.
DB01104SertralineFor the management of major depressive disorder, posttraumatic stress disorder, obsessive-compulsive disorder, panic disorder with or without agoraphobia, premenstrual dysphoric disorder, social phobia, premature ejaculation, and vascular headaches.
DB01175EscitalopramLabeled indications include major depressive disorder (MDD) and generalized anxiety disorder (GAD). Unlabeled indications include treatment of mild dementia-associated agitation in nonpsychotic patients.
DB01191DexfenfluramineFor the management of obesity including weight loss and maintenance of weight loss in patients on a reduced calorie diet
DB01242ClomipramineMay be used to treat obsessive-compulsive disorder and disorders with an obsessive-compulsive component (e.g. depression, schizophrenia, Tourette’s disorder). Unlabeled indications include: depression, panic disorder, chronic pain (e.g. central pain, idiopathic pain disorder, tension headache, diabetic peripheral neuropathy, neuropathic pain), cataplexy and associated narcolepsy (limited evidence), autistic disorder (limited evidence), trichotillomania (limited evidence), onchophagia (limited evidence), stuttering (limited evidence), premature ejaculation, and premenstrual syndrome.
DB01267PaliperidoneFor the treatment of schizophrenia.
DB01445BufotenineNot Available
DB01454MidomafetamineClinical trials are now testing the therapeutic potential of MDMA for post-traumatic stress disorder (PTSD) and anxiety associated with terminal cancer. MDMA is one of the four most widely used illicit drugs in the U.S.
DB014844-Bromo-2,5-dimethoxyamphetamineNot Available
DB01488DimethyltryptamineSome people use this compound as a psychedelic inducing agent.
DB015093,4-MethylenedioxyamphetamineNot Available
DB04829Lysergic Acid DiethylamideNot Available
DB04832ZimelidineFor the treatment of depression.
DB04896MilnacipranMilnacipran is used to treat moderate to severe clinical depression but this indication is not yet FDA-approved in the USA. Milnacipran is labelled for the treatment of fibromyalgia pain.
DB04917RenzaprideFor the treatment of constipation-predominant irritable bowel syndrome (IBS-C).
DB05227APD791For the treatment and prophylaxis of arterial thrombosis.
DB05316PimavanserinInvestigated for use/treatment in neurologic disorders, parkinson's disease, psychosis, schizophrenia and schizoaffective disorders, and sleep disorders.
DB06148MianserinFor the treatment of depression.
DB06153PizotifenNot Available
DB06512DeramciclaneInvestigated for use/treatment in anxiety disorders.
DB06684VilazodoneVilazodone is approved for treatment of acute episodes of major depression. Labeling of vilazodone describes an increased risk of suicidal thoughts in children, adolescents and young adults. The use of vilazodone in pediatrics is not indicated. Its use with monoamine oxidase inhibitors (MAOI) is contraindicated due to increased risk of serotonin syndome. Once the MAOI is discontinued, a 14-day washout period must pass before starting vilazodone.
DB08815LurasidoneTreatment of schizophrenia.
DB08918LevomilnacipranLevomilnacipran is a serotonin and norepinephrine reuptake inhibitor and is indicated for the treatment of major depressive disorder (MDD).
DB08927AmperozideNot Available
DB08953IndalpineNot Available
DB09068VortioxetineVortioxetine is indicated for the treatment of major depressive disorder (MDD).
DB09128BrexpiprazoleAs an adjunctive treatment of major depressive disorder (MDD) and for treatment of schizophrenia.
DB09216Tolfenamic AcidFor the treatment of migraine.
DB09286PipamperoneUsed in the treatment of schizophrenia.
DB09290RamosetronFor the treatment of nausea and vomiting and diarrhea-predominant irritable bowel syndrome in males.
DB11675MosaprideNot Available
DB11699TropisetronFor the prevention of nausea and vomiting induced by cytotoxic therapy and postoperative.
DB12110M-chlorophenylpiperazineNot Available
DB12111MK-212Not Available
DB12163SarpogrelateNot Available
DB12177EplivanserinNot Available
DB12184GepironeNot Available
DB12361PiclozotanNot Available
DB12465KetanserinNot Available
DB12661UrapidilNot Available
DB12693RitanserinNot Available
DB12833TandospironeNot Available
DB12883EltoprazineNot Available
DB13233AlaproclateNot Available
DB13520MetergolineNot Available
DrugDrug NameTargetType
DB00176FluvoxamineSodium-dependent serotonin transportertarget
DB00176FluvoxamineCytochrome P450 1A2enzyme
DB00176FluvoxamineCytochrome P450 2D6enzyme
DB00176FluvoxamineCytochrome P450 2C9enzyme
DB00176FluvoxamineCytochrome P450 2C19enzyme
DB00176FluvoxamineCytochrome P450 1A1enzyme
DB00176FluvoxamineCytochrome P450 3A4enzyme
DB00176FluvoxamineCytochrome P450 3A5enzyme
DB00176FluvoxamineCytochrome P450 3A7enzyme
DB00176FluvoxamineMultidrug resistance protein 1transporter
DB00176FluvoxamineCytochrome P450 2B6enzyme
DB00176FluvoxamineCytochrome P450 2E1enzyme
DB00176FluvoxaminePotassium voltage-gated channel subfamily H member 2target
DB00215CitalopramSodium-dependent serotonin transportertarget
DB00215CitalopramCytochrome P450 2C19enzyme
DB00215CitalopramCytochrome P450 2D6enzyme
DB00215CitalopramCytochrome P450 3A4enzyme
DB00215CitalopramMultidrug resistance protein 1transporter
DB00215CitalopramCytochrome P450 1A2enzyme
DB00215CitalopramCytochrome P450 2B6enzyme
DB00215CitalopramCytochrome P450 2E1enzyme
DB00215CitalopramHistamine H1 receptortarget
DB00215CitalopramSodium-dependent dopamine transportertransporter
DB00215CitalopramSodium-dependent noradrenaline transportertransporter
DB00215CitalopramSodium-dependent serotonin transportertransporter
DB00215CitalopramAlpha-1A adrenergic receptortarget
DB00215CitalopramMuscarinic acetylcholine receptor M1target
DB00215Citalopram5-hydroxytryptamine receptor 2Ctarget
DB00216Eletriptan5-hydroxytryptamine receptor 1Dtarget
DB00216Eletriptan5-hydroxytryptamine receptor 7target
DB00216Eletriptan5-hydroxytryptamine receptor 1Atarget
DB00216Eletriptan5-hydroxytryptamine receptor 1Etarget
DB00216Eletriptan5-hydroxytryptamine receptor 2Btarget
DB00216Eletriptan5-hydroxytryptamine receptor 1Ftarget
DB00216Eletriptan5-hydroxytryptamine receptor 1Btarget
DB00216EletriptanCytochrome P450 3A4enzyme
DB00216EletriptanCytochrome P450 2D6enzyme
DB00216EletriptanCytochrome P450 2C9enzyme
DB00216EletriptanCytochrome P450 2C19enzyme
DB00216EletriptanProstaglandin G/H synthase 1enzyme
DB00216EletriptanCytochrome P450 2A6enzyme
DB00216EletriptanMultidrug resistance protein 1transporter
DB00246ZiprasidoneAlpha-1A adrenergic receptortarget
DB00246ZiprasidoneD(2) dopamine receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 2Ctarget
DB00246ZiprasidoneD(3) dopamine receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 1Atarget
DB00246Ziprasidone5-hydroxytryptamine receptor 1Dtarget
DB00246ZiprasidoneHistamine H1 receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 2Atarget
DB00246ZiprasidoneD(4) dopamine receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 7target
DB00246ZiprasidoneCytochrome P450 3A4enzyme
DB00246ZiprasidoneAlpha-2A adrenergic receptortarget
DB00246ZiprasidoneAlpha-1B adrenergic receptortarget
DB00246ZiprasidoneAlpha-2B adrenergic receptortarget
DB00246ZiprasidoneAlpha-2C adrenergic receptortarget
DB00246ZiprasidoneD(1A) dopamine receptortarget
DB00246ZiprasidoneD(1B) dopamine receptortarget
DB00246ZiprasidoneMuscarinic acetylcholine receptor M1target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M2target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M3target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M4target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M5target
DB00246Ziprasidone5-hydroxytryptamine receptor 1Btarget
DB00246Ziprasidone5-hydroxytryptamine receptor 1Etarget
DB00246Ziprasidone5-hydroxytryptamine receptor 3Atarget
DB00246Ziprasidone5-hydroxytryptamine receptor 6target
DB00246ZiprasidoneCytochrome P450 3A5enzyme
DB00246ZiprasidoneCytochrome P450 3A7enzyme
DB00246ZiprasidoneCytochrome P450 1A2enzyme
DB00246ZiprasidoneCytochrome P450 2D6enzyme
DB00247Methysergide5-hydroxytryptamine receptor 2Atarget
DB00247Methysergide5-hydroxytryptamine receptor 1Atarget
DB00247Methysergide5-hydroxytryptamine receptor 7target
DB00247Methysergide5-hydroxytryptamine receptor 2Ctarget
DB00247Methysergide5-hydroxytryptamine receptor 2Btarget
DB00247Methysergide5-hydroxytryptamine receptor 1Btarget
DB00247Methysergide5-hydroxytryptamine receptor 1Ftarget
DB00247Methysergide5-hydroxytryptamine receptor 1Etarget
DB00315Zolmitriptan5-hydroxytryptamine receptor 1Dtarget
DB00315Zolmitriptan5-hydroxytryptamine receptor 1Btarget
DB00315Zolmitriptan5-hydroxytryptamine receptor 1Ftarget
DB00315ZolmitriptanCytochrome P450 1A2enzyme
DB00315ZolmitriptanAmine oxidase [flavin-containing] Aenzyme
DB00315Zolmitriptan5-hydroxytryptamine receptor 1Atarget
DB00334OlanzapineMuscarinic acetylcholine receptor M5target
DB00334OlanzapineD(1A) dopamine receptortarget
DB00334OlanzapineMuscarinic acetylcholine receptor M1target
DB00334OlanzapineMuscarinic acetylcholine receptor M3target
DB00334Olanzapine5-hydroxytryptamine receptor 2Atarget
DB00334OlanzapineD(4) dopamine receptortarget
DB00334OlanzapineHistamine H1 receptortarget
DB00334OlanzapineMuscarinic acetylcholine receptor M4target
DB00334OlanzapineMuscarinic acetylcholine receptor M2target
DB00334OlanzapineD(2) dopamine receptortarget
DB00334Olanzapine5-hydroxytryptamine receptor 2Ctarget
DB00334OlanzapineD(3) dopamine receptortarget
DB00334OlanzapineAlpha-1B adrenergic receptortarget
DB00334OlanzapineCytochrome P450 1A2enzyme
DB00334Olanzapine5-hydroxytryptamine receptor 1Atarget
DB00334Olanzapine5-hydroxytryptamine receptor 1Btarget
DB00334Olanzapine5-hydroxytryptamine receptor 1Dtarget
DB00334Olanzapine5-hydroxytryptamine receptor 1Etarget
DB00334Olanzapine5-hydroxytryptamine receptor 3Atarget
DB00334Olanzapine5-hydroxytryptamine receptor 6target
DB00334Olanzapine5-hydroxytryptamine receptor 7target
DB00334OlanzapineAlpha-1A adrenergic receptortarget
DB00334OlanzapineAlpha-2A adrenergic receptortarget
DB00334OlanzapineAlpha-2B adrenergic receptortarget
DB00334OlanzapineAlpha-2C adrenergic receptortarget
DB00334OlanzapineD(1B) dopamine receptortarget
DB00334OlanzapineSerum albumincarrier
DB00334OlanzapineAlpha-1-acid glycoprotein 1carrier
DB00334OlanzapineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00334OlanzapineCytochrome P450 2D6enzyme
DB00334OlanzapineMultidrug resistance protein 1transporter
DB00334OlanzapineCytochrome P450 2C19enzyme
DB00334OlanzapineCytochrome P450 2C9enzyme
DB00334OlanzapineCytochrome P450 3A4enzyme
DB00334Olanzapine5-hydroxytryptamine receptor 2Btarget
DB00334Olanzapine5-hydroxytryptamine receptor 5Atarget
DB00334OlanzapineD(1) dopamine receptortarget
DB00334OlanzapineHistamine H2 receptortarget
DB00334OlanzapineHistamine H4 receptortarget
DB00334OlanzapineGABA-A receptor (anion channel)target
DB00334OlanzapineBeta adrenergic receptortarget
DB00334OlanzapineD(2L) dopamine receptortarget
DB00334OlanzapineD(2S) dopamine receptortarget
DB00363ClozapineD(4) dopamine receptortarget
DB00363ClozapineHistamine H1 receptortarget
DB00363ClozapineD(2) dopamine receptortarget
DB00363ClozapineNeuron-specific vesicular protein calcyontarget
DB00363ClozapineHistamine H4 receptortarget
DB00363Clozapine5-hydroxytryptamine receptor 2Atarget
DB00363Clozapine5-hydroxytryptamine receptor 1Atarget
DB00363Clozapine5-hydroxytryptamine receptor 2Ctarget
DB00363ClozapineD(1A) dopamine receptortarget
DB00363ClozapineCytochrome P450 1A2enzyme
DB00363ClozapineCytochrome P450 2D6enzyme
DB00363ClozapineD(3) dopamine receptortarget
DB00363ClozapineMuscarinic acetylcholine receptor M1target
DB00363ClozapineMuscarinic acetylcholine receptor M2target
DB00363ClozapineMuscarinic acetylcholine receptor M3target
DB00363ClozapineMuscarinic acetylcholine receptor M4target
DB00363ClozapineMuscarinic acetylcholine receptor M5target
DB00363Clozapine5-hydroxytryptamine receptor 1Btarget
DB00363Clozapine5-hydroxytryptamine receptor 1Dtarget
DB00363Clozapine5-hydroxytryptamine receptor 1Etarget
DB00363Clozapine5-hydroxytryptamine receptor 3Atarget
DB00363Clozapine5-hydroxytryptamine receptor 6target
DB00363Clozapine5-hydroxytryptamine receptor 7target
DB00363ClozapineAlpha-1A adrenergic receptortarget
DB00363ClozapineAlpha-1B adrenergic receptortarget
DB00363ClozapineAlpha-2A adrenergic receptortarget
DB00363ClozapineAlpha-2B adrenergic receptortarget
DB00363ClozapineAlpha-2C adrenergic receptortarget
DB00363ClozapineCytochrome P450 2C9enzyme
DB00363ClozapineMultidrug resistance protein 1transporter
DB00363ClozapineCytochrome P450 3A4enzyme
DB00363ClozapineCytochrome P450 2C19enzyme
DB00363ClozapineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00363ClozapineUDP-glucuronosyltransferase 1-4enzyme
DB00363ClozapineCytochrome P450 1A1enzyme
DB00363ClozapineCytochrome P450 1B1enzyme
DB00363ClozapineCytochrome P450 2A6enzyme
DB00363ClozapineCytochrome P450 2C8enzyme
DB00363ClozapineCytochrome P450 2E1enzyme
DB00363ClozapineGlutathione S-transferase Ptarget
DB00377Palonosetron5-hydroxytryptamine receptor 3Atarget
DB00377PalonosetronCytochrome P450 2D6enzyme
DB00377PalonosetronCytochrome P450 3A4enzyme
DB00377PalonosetronCytochrome P450 1A2enzyme
DB00434Cyproheptadine5-hydroxytryptamine receptor 2Atarget
DB00434CyproheptadineHistamine H1 receptortarget
DB00434CyproheptadineMuscarinic acetylcholine receptor M1target
DB00434CyproheptadineMuscarinic acetylcholine receptor M2target
DB00434CyproheptadineMuscarinic acetylcholine receptor M3target
DB00434Cyproheptadine5-hydroxytryptamine receptor 2Ctarget
DB00434CyproheptadineUDP-glucuronosyltransferase 1-3enzyme
DB00434Cyproheptadine5-hydroxytryptamine receptor 7target
DB00472FluoxetineSodium-dependent serotonin transportertarget
DB00472FluoxetineCytochrome P450 2C9enzyme
DB00472FluoxetineCytochrome P450 2D6enzyme
DB00472FluoxetineCYP2B proteinenzyme
DB00472FluoxetineCytochrome P450 1A2enzyme
DB00472FluoxetineCytochrome P450 3A4enzyme
DB00472FluoxetineCytochrome P450 2C19enzyme
DB00472FluoxetineMultidrug resistance protein 1transporter
DB00472FluoxetineCytochrome P450 2B6enzyme
DB00472FluoxetineCytochrome P450 3A5enzyme
DB00472FluoxetineSerum albumincarrier
DB00472FluoxetineAlpha-1-acid glycoprotein 1carrier
DB00472FluoxetinePotassium voltage-gated channel subfamily H member 2target
DB00472Fluoxetine5-hydroxytryptamine receptor 2Ctarget
DB00472FluoxetineCyclin-dependent kinases regulatory subunit 1target
DB00490Buspirone5-hydroxytryptamine receptor 1Atarget
DB00490BuspironeD(2) dopamine receptortarget
DB00490BuspironeCytochrome P450 3A4enzyme
DB00490BuspironeCytochrome P450 3A5enzyme
DB00490BuspironeCytochrome P450 3A7enzyme
DB00490BuspironeMultidrug resistance protein 1transporter
DB00490BuspironeCytochrome P450 2D6enzyme
DB00543AmoxapineSodium-dependent serotonin transportertarget
DB00543AmoxapineSodium-dependent noradrenaline transportertarget
DB00543AmoxapineAlpha-2A adrenergic receptortarget
DB00543AmoxapineD(2) dopamine receptortarget
DB00543AmoxapineAlpha-1A adrenergic receptortarget
DB00543AmoxapineD(1A) dopamine receptortarget
DB00543AmoxapineMuscarinic acetylcholine receptor M1target
DB00543AmoxapineGamma-aminobutyric acid receptor subunit alpha-1target
DB00543AmoxapineAlpha-1-acid glycoprotein 1carrier
DB00543AmoxapineCytochrome P450 2D6enzyme
DB00543Amoxapine5-hydroxytryptamine receptor 2Atarget
DB00543Amoxapine5-hydroxytryptamine receptor 2Ctarget
DB00543Amoxapine5-hydroxytryptamine receptor 6target
DB00543Amoxapine5-hydroxytryptamine receptor 7target
DB00543AmoxapineD(3) dopamine receptortarget
DB00543AmoxapineD(4) dopamine receptortarget
DB00543AmoxapineHistamine H1 receptortarget
DB00543AmoxapineAlpha-1 adrenergic receptorstarget
DB00543AmoxapineMuscarinic acetylcholine receptortarget
DB00543Amoxapine5-hydroxytryptamine receptor 2Btarget
DB00543Amoxapine5-hydroxytryptamine receptor 3Atarget
DB00543Amoxapine5-hydroxytryptamine receptor 1Atarget
DB00543Amoxapine5-hydroxytryptamine receptor 1Btarget
DB00543AmoxapineAlpha-2 adrenergic receptorstarget
DB00543AmoxapineHistamine H4 receptortarget
DB00543AmoxapineGABA-A receptor (anion channel)target
DB00543AmoxapineSodium-dependent dopamine transportertarget
DB00574Fenfluramine5-hydroxytryptamine receptor 2Ctarget
DB00574Fenfluramine5-hydroxytryptamine receptor 2Btarget
DB00574FenfluramineCytochrome P450 2D6enzyme
DB00574FenfluramineSodium-dependent serotonin transportertarget
DB00574Fenfluramine5-hydroxytryptamine receptor 2Atarget
DB00589LisurideD(1A) dopamine receptortarget
DB00589Lisuride5-hydroxytryptamine receptor 1Atarget
DB00589LisurideD(2) dopamine receptortarget
DB00589LisurideAlpha-2A adrenergic receptortarget
DB00589LisurideAlpha-2B adrenergic receptortarget
DB00589LisurideAlpha-2C adrenergic receptortarget
DB00589LisurideD(3) dopamine receptortarget
DB00589Lisuride5-hydroxytryptamine receptor 1Dtarget
DB00589Lisuride5-hydroxytryptamine receptor 2Btarget
DB00589Lisuride5-hydroxytryptamine receptor 2Atarget
DB00589LisurideD(4) dopamine receptortarget
DB00589Lisuride5-hydroxytryptamine receptor 2Ctarget
DB00589LisurideD(1B) dopamine receptortarget
DB00589Lisuride5-hydroxytryptamine receptor 1Btarget
DB00589LisurideCytochrome P450 2D6enzyme
DB00589LisurideCytochrome P450 3A4enzyme
DB00589Lisuride5-hydroxytryptamine receptor 7target
DB00604Cisapride5-hydroxytryptamine receptor 4target
DB00604Cisapride5-hydroxytryptamine receptor 3Atarget
DB00604CisapridePotassium voltage-gated channel subfamily H member 2target
DB00604Cisapride5-hydroxytryptamine receptor 2Atarget
DB00604CisaprideCytochrome P450 3A4enzyme
DB00604CisaprideCytochrome P450 3A5enzyme
DB00604CisaprideCytochrome P450 3A7enzyme
DB00604CisaprideCytochrome P450 1A2enzyme
DB00604CisaprideCytochrome P450 2A6enzyme
DB00604CisaprideCytochrome P450 2B6enzyme
DB00604CisaprideCytochrome P450 2C19enzyme
DB00604CisaprideCytochrome P450 2C8enzyme
DB00604CisaprideCytochrome P450 2C9enzyme
DB00604CisaprideCytochrome P450 2D6enzyme
DB00656Trazodone5-hydroxytryptamine receptor 2Atarget
DB00656TrazodoneSodium-dependent serotonin transportertarget
DB00656TrazodoneAlpha-1A adrenergic receptortarget
DB00656TrazodoneAlpha-2A adrenergic receptortarget
DB00656TrazodoneHistamine H1 receptortarget
DB00656Trazodone5-hydroxytryptamine receptor 1Atarget
DB00656TrazodoneCytochrome P450 2D6enzyme
DB00656TrazodoneCytochrome P450 3A4enzyme
DB00656Trazodone5-hydroxytryptamine receptor 2Ctarget
DB00656TrazodoneAlpha-1-acid glycoprotein 1carrier
DB00656TrazodoneCytochrome P450 3A5enzyme
DB00656TrazodoneCytochrome P450 3A7enzyme
DB00656TrazodoneMultidrug resistance protein 1transporter
DB00669Sumatriptan5-hydroxytryptamine receptor 1Dtarget
DB00669Sumatriptan5-hydroxytryptamine receptor 1Btarget
DB00669Sumatriptan5-hydroxytryptamine receptor 1Ftarget
DB00669SumatriptanAmine oxidase [flavin-containing] Aenzyme
DB00669Sumatriptan5-hydroxytryptamine receptor 1Atarget
DB00669SumatriptanSolute carrier organic anion transporter family member 1A2transporter
DB00669SumatriptanMultidrug resistance protein 1transporter
DB00669SumatriptanATP-binding cassette sub-family G member 2transporter
DB00669SumatriptanSolute carrier organic anion transporter family member 1B1transporter
DB00696ErgotamineAlpha-1A adrenergic receptortarget
DB00696Ergotamine5-hydroxytryptamine receptor 1Dtarget
DB00696Ergotamine5-hydroxytryptamine receptor 1Btarget
DB00696Ergotamine5-hydroxytryptamine receptor 2Atarget
DB00696ErgotamineAlpha-2A adrenergic receptortarget
DB00696ErgotamineD(2) dopamine receptortarget
DB00696ErgotamineAlpha-2B adrenergic receptortarget
DB00696ErgotamineSodium-dependent noradrenaline transportertarget
DB00696ErgotamineCytochrome P450 3A4enzyme
DB00696ErgotamineAlpha-1B adrenergic receptortarget
DB00696ErgotamineAlpha-1D adrenergic receptortarget
DB00696ErgotamineMultidrug resistance protein 1transporter
DB00696ErgotamineCytochrome P450 1A2enzyme
DB00696ErgotamineD(1) dopamine receptortarget
DB00696Ergotamine5-hydroxytryptamine receptor 1Atarget
DB00696Ergotamine5-hydroxytryptamine receptor 1Ftarget
DB00696Ergotamine5-hydroxytryptamine receptor 2Ctarget
DB00696Ergotamine5-hydroxytryptamine receptor 2Btarget
DB00715ParoxetineSodium-dependent serotonin transportertarget
DB00715ParoxetineSodium-dependent noradrenaline transportertarget
DB00715Paroxetine5-hydroxytryptamine receptor 2Atarget
DB00715ParoxetineCytochrome P450 2D6enzyme
DB00715ParoxetineMuscarinic acetylcholine receptor M1target
DB00715ParoxetineMuscarinic acetylcholine receptor M2target
DB00715ParoxetineMuscarinic acetylcholine receptor M3target
DB00715ParoxetineMuscarinic acetylcholine receptor M4target
DB00715ParoxetineMuscarinic acetylcholine receptor M5target
DB00715ParoxetineCytochrome P450 2C9enzyme
DB00715ParoxetineMultidrug resistance protein 1transporter
DB00715ParoxetineCytochrome P450 2B6enzyme
DB00715ParoxetineCytochrome P450 2C8enzyme
DB00715ParoxetineCytochrome P450 1A2enzyme
DB00734RisperidoneHistamine H1 receptortarget
DB00734RisperidoneD(2) dopamine receptortarget
DB00734RisperidoneAlpha-1A adrenergic receptortarget
DB00734Risperidone5-hydroxytryptamine receptor 2Atarget
DB00734RisperidoneAlpha-1B adrenergic receptortarget
DB00734RisperidoneCytochrome P450 2D6enzyme
DB00734RisperidoneD(1A) dopamine receptortarget
DB00734RisperidoneAlpha-2A adrenergic receptortarget
DB00734RisperidoneAlpha-2B adrenergic receptortarget
DB00734RisperidoneAlpha-2C adrenergic receptortarget
DB00734Risperidone5-hydroxytryptamine receptor 1Atarget
DB00734Risperidone5-hydroxytryptamine receptor 1Dtarget
DB00734Risperidone5-hydroxytryptamine receptor 2Ctarget
DB00734RisperidoneD(3) dopamine receptortarget
DB00734RisperidoneD(4) dopamine receptortarget
DB00734RisperidoneCytochrome P450 3A4enzyme
DB00734RisperidoneCytochrome P450 3A5enzyme
DB00734RisperidoneCytochrome P450 3A7enzyme
DB00734RisperidoneMultidrug resistance protein 1transporter
DB00734Risperidone5-hydroxytryptamine receptor 7target
DB00757Dolasetron5-hydroxytryptamine receptor 3Atarget
DB00757DolasetronCytochrome P450 3A4enzyme
DB00757DolasetronCytochrome P450 2D6enzyme
DB00757DolasetronCytochrome P450 2C9enzyme
DB00889Granisetron5-hydroxytryptamine receptor 3Atarget
DB00889GranisetronCytochrome P450 3A4enzyme
DB00889GranisetronCytochrome P450 1A1enzyme
DB00889GranisetronCytochrome P450 2D6enzyme
DB00889GranisetronCytochrome P450 3A5enzyme
DB00904Ondansetron5-hydroxytryptamine receptor 3Atarget
DB00904OndansetronCytochrome P450 3A4enzyme
DB00904OndansetronCytochrome P450 1A2enzyme
DB00904OndansetronCytochrome P450 2D6enzyme
DB00904OndansetronCytochrome P450 3A5enzyme
DB00904OndansetronCytochrome P450 3A7enzyme
DB00904Ondansetron5-hydroxytryptamine receptor 4target
DB00904Ondansetron5-hydroxytryptamine receptor 1Atarget
DB00904Ondansetron5-hydroxytryptamine receptor 1Btarget
DB00904OndansetronMu-type opioid receptortarget
DB00904OndansetronCytochrome P450 2C9enzyme
DB00904OndansetronCytochrome P450 2E1enzyme
DB00918Almotriptan5-hydroxytryptamine receptor 1Dtarget
DB00918Almotriptan5-hydroxytryptamine receptor 1Btarget
DB00918AlmotriptanCytochrome P450 3A4enzyme
DB00918AlmotriptanCytochrome P450 2D6enzyme
DB00918AlmotriptanAmine oxidase [flavin-containing] Aenzyme
DB00918AlmotriptanDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00918AlmotriptanCytochrome P450 1A2enzyme
DB00918AlmotriptanCytochrome P450 2C19enzyme
DB00918AlmotriptanCytochrome P450 2E1enzyme
DB00918AlmotriptanCytochrome P450 2C8enzyme
DB00952Naratriptan5-hydroxytryptamine receptor 1Dtarget
DB00952Naratriptan5-hydroxytryptamine receptor 1Btarget
DB00952Naratriptan5-hydroxytryptamine receptor 1Ftarget
DB00952Naratriptan5-hydroxytryptamine receptor 1Atarget
DB00952NaratriptanAmine oxidase [flavin-containing] Aenzyme
DB00953Rizatriptan5-hydroxytryptamine receptor 1Dtarget
DB00953Rizatriptan5-hydroxytryptamine receptor 1Btarget
DB00953Rizatriptan5-hydroxytryptamine receptor 1Ftarget
DB00953RizatriptanAmine oxidase [flavin-containing] Aenzyme
DB00953RizatriptanCytochrome P450 1A2enzyme
DB00960PindololBeta-1 adrenergic receptortarget
DB00960PindololBeta-2 adrenergic receptortarget
DB00960Pindolol5-hydroxytryptamine receptor 1Atarget
DB00960Pindolol5-hydroxytryptamine receptor 1Btarget
DB00960PindololCytochrome P450 2D6enzyme
DB00960PindololBeta-3 adrenergic receptortarget
DB00969Alosetron5-hydroxytryptamine receptor 3Atarget
DB00969AlosetronCytochrome P450 1A2enzyme
DB00969AlosetronCytochrome P450 2C9enzyme
DB00969AlosetronCytochrome P450 3A4enzyme
DB00969AlosetronCytochrome P450 2E1enzyme
DB00998Frovatriptan5-hydroxytryptamine receptor 1Dtarget
DB00998Frovatriptan5-hydroxytryptamine receptor 1Btarget
DB00998FrovatriptanCytochrome P450 1A2enzyme
DB01079Tegaserod5-hydroxytryptamine receptor 4target
DB01079Tegaserod5-hydroxytryptamine receptor 2Btarget
DB01079Tegaserod5-hydroxytryptamine receptor 2Ctarget
DB01079Tegaserod5-hydroxytryptamine receptor 2Atarget
DB01079TegaserodSodium-dependent serotonin transportertransporter
DB01079TegaserodCytochrome P450 1A2enzyme
DB01079TegaserodCytochrome P450 2C8enzyme
DB01079TegaserodCytochrome P450 2C9enzyme
DB01079TegaserodCytochrome P450 2D6enzyme
DB01079TegaserodCytochrome P450 2E1enzyme
DB01104SertralineSodium-dependent serotonin transportertarget
DB01104SertralineCytochrome P450 2B6enzyme
DB01104SertralineCytochrome P450 2C19enzyme
DB01104SertralineCytochrome P450 2C9enzyme
DB01104SertralineCytochrome P450 2D6enzyme
DB01104SertralineSodium-dependent dopamine transportertarget
DB01104SertralineCYP2B proteinenzyme
DB01104SertralineCytochrome P450 3A4enzyme
DB01104SertralineAmine oxidase [flavin-containing] Benzyme
DB01104SertralineAmine oxidase [flavin-containing] Aenzyme
DB01104SertralineMultidrug resistance protein 1transporter
DB01104SertralineCytochrome P450 1A2enzyme
DB01104SertralineSerum albumincarrier
DB01175EscitalopramSodium-dependent serotonin transportertarget
DB01175EscitalopramCytochrome P450 3A4enzyme
DB01175EscitalopramCytochrome P450 2D6enzyme
DB01175EscitalopramSodium-dependent dopamine transportertarget
DB01175EscitalopramSodium-dependent noradrenaline transportertarget
DB01175EscitalopramAlpha-1A adrenergic receptortarget
DB01175EscitalopramMuscarinic acetylcholine receptor M1target
DB01175EscitalopramHistamine H1 receptortarget
DB01175EscitalopramCytochrome P450 2C19enzyme
DB01191DexfenfluramineSodium-dependent serotonin transportertarget
DB01191Dexfenfluramine5-hydroxytryptamine receptor 2Ctarget
DB01191DexfenfluramineCytochrome P450 2D6enzyme
DB01191DexfenfluramineCytochrome P450 1A2enzyme
DB01191DexfenfluramineCytochrome P450 2A6enzyme
DB01191DexfenfluramineCytochrome P450 2C19enzyme
DB01191DexfenfluramineCytochrome P450 2C9enzyme
DB01191DexfenfluramineCytochrome P450 2E1enzyme
DB01242ClomipramineSodium-dependent serotonin transportertarget
DB01242ClomipramineSodium-dependent noradrenaline transportertarget
DB01242ClomipramineGlutathione S-transferase Ptarget
DB01242Clomipramine5-hydroxytryptamine receptor 2Atarget
DB01242ClomipramineCytochrome P450 1A2enzyme
DB01242ClomipramineCytochrome P450 2D6enzyme
DB01242ClomipramineCytochrome P450 2C19enzyme
DB01242ClomipramineMultidrug resistance protein 1transporter
DB01242ClomipramineCytochrome P450 3A4enzyme
DB01242Clomipramine5-hydroxytryptamine receptor 2Btarget
DB01242Clomipramine5-hydroxytryptamine receptor 2Ctarget
DB01242ClomipramineSerum albumincarrier
DB01267PaliperidoneD(2) dopamine receptortarget
DB01267Paliperidone5-hydroxytryptamine receptor 2Atarget
DB01267PaliperidoneHistamine H1 receptortarget
DB01267PaliperidoneAlpha-1A adrenergic receptortarget
DB01267PaliperidoneAlpha-1B adrenergic receptortarget
DB01267PaliperidoneD(3) dopamine receptortarget
DB01267PaliperidoneD(4) dopamine receptortarget
DB01267PaliperidoneD(1A) dopamine receptortarget
DB01267PaliperidoneAlpha-2A adrenergic receptortarget
DB01267PaliperidoneAlpha-2B adrenergic receptortarget
DB01267PaliperidoneAlpha-2C adrenergic receptortarget
DB01267Paliperidone5-hydroxytryptamine receptor 1Atarget
DB01267Paliperidone5-hydroxytryptamine receptor 1Dtarget
DB01267Paliperidone5-hydroxytryptamine receptor 2Ctarget
DB01267PaliperidoneCytochrome P450 3A4target
DB01267PaliperidoneCytochrome P450 2D6target
DB01267PaliperidoneCytochrome P450 3A5target
DB01267Paliperidone5-hydroxytryptamine receptor 7target
DB01445BufotenineAmine oxidase [flavin-containing] Aenzyme
DB01445BufotenineAmine oxidase [flavin-containing] Benzyme
DB01454MidomafetamineSodium-dependent serotonin transportertarget
DB01454MidomafetamineSynaptic vesicular amine transportertarget
DB01454MidomafetamineSodium-dependent dopamine transportertarget
DB01454Midomafetamine5-hydroxytryptamine receptor 2Atarget
DB01454Midomafetamine5-hydroxytryptamine receptor 2Btarget
DB01454Midomafetamine5-hydroxytryptamine receptor 2Ctarget
DB01454MidomafetamineSodium-dependent noradrenaline transportertarget
DB01454MidomafetamineSodium-dependent noradrenaline transportertransporter
DB01454MidomafetamineSodium-dependent dopamine transportertransporter
DB01454MidomafetamineSodium-dependent serotonin transportertransporter
DB01488Dimethyltryptamine5-hydroxytryptamine receptor 6target
DB01488Dimethyltryptamine5-hydroxytryptamine receptor 2Atarget
DB01488DimethyltryptamineSigma non-opioid intracellular receptor 1target
DB04829Lysergic Acid Diethylamide5-hydroxytryptamine receptor 1Atarget
DB04829Lysergic Acid Diethylamide5-hydroxytryptamine receptor 2Btarget
DB04829Lysergic Acid Diethylamide5-hydroxytryptamine receptor 6target
DB04832ZimelidineSodium-dependent serotonin transportertarget
DB04832ZimelidineMultidrug resistance protein 1transporter
DB04832ZimelidineAmine oxidase [flavin-containing] Btarget
DB04832ZimelidineAmine oxidase [flavin-containing] Atarget
DB04896MilnacipranSodium-dependent serotonin transportertarget
DB04896MilnacipranSodium-dependent noradrenaline transportertarget
DB04896MilnacipranNMDA receptortarget
DB04917Renzapride5-hydroxytryptamine receptor 3Atarget
DB04917Renzapride5-hydroxytryptamine receptor 4target
DB05227APD7915-hydroxytryptamine receptor 2Atarget
DB05316Pimavanserin5-hydroxytryptamine receptor 2Atarget
DB05316PimavanserinD(2) dopamine receptortarget
DB06148MianserinHistamine H1 receptortarget
DB06148MianserinAlpha-2A adrenergic receptortarget
DB06148Mianserin5-hydroxytryptamine receptor 2Atarget
DB06148Mianserin5-hydroxytryptamine receptor 2Ctarget
DB06148MianserinCytochrome P450 2D6enzyme
DB06148MianserinSodium-dependent serotonin transportertarget
DB06148MianserinCytochrome P450 3A4enzyme
DB06148MianserinCytochrome P450 1A2enzyme
DB06148MianserinCytochrome P450 2B6enzyme
DB06148MianserinSodium-dependent noradrenaline transportertarget
DB06148MianserinHistamine H4 receptortarget
DB06148Mianserin5-hydroxytryptamine receptor 1Atarget
DB06148MianserinAlpha-2C adrenergic receptortarget
DB06148Mianserin5-hydroxytryptamine receptor 2Btarget
DB06148Mianserin5-hydroxytryptamine receptor 1Ftarget
DB06148MianserinAlpha-2B adrenergic receptortarget
DB06148MianserinD(3) dopamine receptortarget
DB06148MianserinKappa-type opioid receptortarget
DB06148MianserinSodium-dependent dopamine transportertarget
DB06148Mianserin5-hydroxytryptamine receptor 7target
DB06148MianserinD(2) dopamine receptortarget
DB06148Mianserin5-hydroxytryptamine receptor 6target
DB06148MianserinAlpha-1 adrenergic receptorstarget
DB06148MianserinD(1) dopamine receptortarget
DB06512Deramciclane5-hydroxytryptamine receptor 2Atarget
DB06512Deramciclane5-hydroxytryptamine receptor 2Ctarget
DB06512DeramciclaneCytochrome P450 2D6enzyme
DB06684Vilazodone5-hydroxytryptamine receptor 1Atarget
DB06684VilazodoneCytochrome P450 3A4enzyme
DB06684VilazodoneCytochrome P450 2C18enzyme
DB06684VilazodoneCytochrome P450 2D6enzyme
DB06684VilazodoneSodium-dependent serotonin transportertransporter
DB08815LurasidoneCytochrome P450 3A4enzyme
DB08815LurasidoneD(2) dopamine receptortarget
DB08815Lurasidone5-hydroxytryptamine receptor 2Atarget
DB08815Lurasidone5-hydroxytryptamine receptor 7target
DB08815Lurasidone5-hydroxytryptamine receptor 1Atarget
DB08815LurasidoneAlpha-2C adrenergic receptortarget
DB08815LurasidoneAlpha-2A adrenergic receptortarget
DB08918LevomilnacipranCytochrome P450 3A4enzyme
DB08918LevomilnacipranCytochrome P450 2C8enzyme
DB08918LevomilnacipranCytochrome P450 2C19enzyme
DB08918LevomilnacipranCytochrome P450 2D6enzyme
DB08918LevomilnacipranCytochrome P450 2J2enzyme
DB08918LevomilnacipranSodium-dependent serotonin transportertarget
DB08918LevomilnacipranSodium-dependent noradrenaline transportertarget
DB08918LevomilnacipranMultidrug resistance protein 1transporter
DB08927Amperozide5-hydroxytryptamine receptor 2Atarget
DB09068VortioxetineSodium-dependent serotonin transportertarget
DB09068Vortioxetine5-hydroxytryptamine receptor 3Atarget
DB09068Vortioxetine5-hydroxytryptamine receptor 7target
DB09068Vortioxetine5-hydroxytryptamine receptor 1Btarget
DB09068Vortioxetine5-hydroxytryptamine receptor 1Atarget
DB09068VortioxetineBeta-1 adrenergic receptortarget
DB09068Vortioxetinesolute carrier family 6 member 2target
DB09068VortioxetineCytochrome P450 2D6enzyme
DB09068VortioxetineCytochrome P450 3A4enzyme
DB09068VortioxetineCytochrome P450 3A5enzyme
DB09068VortioxetineCytochrome P450 2C19enzyme
DB09068VortioxetineCytochrome P450 2C9enzyme
DB09068VortioxetineCytochrome P450 2A6enzyme
DB09068VortioxetineCytochrome P450 2C8enzyme
DB09068VortioxetineCytochrome P450 2B6enzyme
DB09128BrexpiprazoleCytochrome P450 2D6enzyme
DB09128BrexpiprazoleCytochrome P450 3A4enzyme
DB09128Brexpiprazole5-hydroxytryptamine receptor 1Atarget
DB09128BrexpiprazoleD(2) dopamine receptortarget
DB09128Brexpiprazole5-hydroxytryptamine receptor 2Atarget
DB09128BrexpiprazoleAlpha-2C adrenergic receptortarget
DB09128BrexpiprazoleAlpha-1B adrenergic receptortarget
DB09290Ramosetron5-hydroxytryptamine receptor 3Atarget
DB11699Tropisetron5-hydroxytryptamine receptor 3Atarget
DB12163Sarpogrelate5-hydroxytryptamine receptor 2Ctarget
DB12163Sarpogrelate5-hydroxytryptamine receptor 2Atarget
DB12465Ketanserin5-hydroxytryptamine receptor 2Atarget
DB12693Ritanserin5-hydroxytryptamine receptor 2Atarget
DB13520MetergolineSodium channel protein type 2 subunit alphatarget