Displaying drugs 1576 - 1600 of 2778 in total
Name | Weight | Structure | Description | Categories |
---|---|---|---|---|
Olutasidenib | 354.79 C18H15ClN4O2 | An isocitrate dehydrogenase-1 (IDH1) inhibitor indicated for the treatment of patients with relapsed or refractory acute myeloid leukemia with a susceptible IDH1 mutation as detected by an FDA-approved test. | Antineoplastic Agents / BCRP/ABCG2 Inhibitors / Cytochrome P-450 CYP1A2 Inducers / Cytochrome P-450 CYP1A2 Inducers (strength unknown) / Cytochrome P-450 CYP1A2 Substrates / Cytochrome P-450 CYP2B6 Inducers / Cytochrome P-450 CYP2B6 Inducers (strength unknown) / Cytochrome P-450 CYP2C19 Substrates / Cytochrome P-450 CYP2C8 Inducers / Cytochrome P-450 CYP2C8 Inducers (strength unknown) / Cytochrome P-450 CYP2C8 Substrates / Cytochrome P-450 CYP2C9 Inducers / Cytochrome P-450 CYP2C9 Inducers (strength unknown) / Cytochrome P-450 CYP2C9 Substrates / Cytochrome P-450 CYP3A Inducers / Cytochrome P-450 CYP3A Substrates / Cytochrome P-450 CYP3A4 Inducers / Cytochrome P-450 CYP3A4 Inducers (strength unknown) / Cytochrome P-450 CYP3A4 Substrates / Cytochrome P-450 Enzyme Inducers / Cytochrome P-450 Substrates / Enzyme Inhibitors / Heterocyclic Compounds, Fused-Ring / Isocitrate dehydrogenase-1 (IDH1) inhibitors / Isocitrate Dehydrogenase-1 Inhibitors / MATE 1 Inhibitors / MATE 2 Inhibitors / MATE inhibitors / OAT3/SLC22A8 Inhibitors / OATP1B1/SLCO1B1 Inhibitors / OATP1B3 inhibitors / OCT2 Inhibitors / P-glycoprotein inhibitors / Potential QTc-Prolonging Agents / QTc Prolonging Agents | |
Repotrectinib | 355.373 C18H18FN5O2 | A tyrosine kinase inhibitor used to treat locally active or metastatic non-small cell lung cancer | BCRP/ABCG2 Inhibitors / Cytochrome P-450 CYP2B6 Inducers / Cytochrome P-450 CYP2B6 Inducers (strength unknown) / Cytochrome P-450 CYP2C19 Inducers / Cytochrome P-450 CYP2C19 Inducers (strength unknown) / Cytochrome P-450 CYP2C8 Inducers / Cytochrome P-450 CYP2C8 Inducers (strength unknown) / Cytochrome P-450 CYP2C9 Inducers / Cytochrome P-450 CYP2C9 Inducers (strength unknown) / Cytochrome P-450 CYP3A Inducers / Cytochrome P-450 CYP3A Inhibitors / Cytochrome P-450 CYP3A Substrates / Cytochrome P-450 CYP3A4 Inducers / Cytochrome P-450 CYP3A4 Inducers (strength unknown) / Cytochrome P-450 CYP3A4 Inhibitors / Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) / Cytochrome P-450 CYP3A4 Substrates / Cytochrome P-450 CYP3A5 Inhibitors / Cytochrome P-450 CYP3A5 Inhibitors (strength unknown) / Cytochrome P-450 Enzyme Inducers / Cytochrome P-450 Enzyme Inhibitors / Cytochrome P-450 Substrates / Kinase Inhibitor / MATE 2 Inhibitors / MATE inhibitors / OATP1B1/SLCO1B1 Inhibitors / P-glycoprotein inhibitors / P-glycoprotein substrates / ROS1 tyrosine kinase inhibitors / Tyrosine Kinase Inhibitors / UGT1A1 Inhibitors | |
Technetium Tc-99m sulfur colloid | 355.39 S8Tc | A radiopharmaceutical diagnostic agent used for the localization of lymph nodes, evaluation of peritoneovenous (LeVeen) shunt patency, imaging areas of functioning reticuloendothelial cells, and gastrointestinal imaging. | Technetium (99Mtc), Particles and Colloids | |
Amodiaquine | 355.861 C20H22ClN3O | An antimalarial drug. | Aminoquinolines | |
Bithionol | 356.052 C12H6Cl4O2S | Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the... | Preparations Containing Sulfur | |
Pipobroman | 356.054 C10H16Br2N2O2 | For the treatment of polycythaemia vera and refractory chronic myeloid leukaemia. | Alkylating Drugs / Antineoplastic Agents | |
Sulindac | 356.411 C20H17FO3S | An NSAID used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute subacromial bursitis or supraspinatus tendinitis, and acute gouty arthritis. | Acetic Acid Derivatives and Related Substances | |
Pioglitazone | 356.439 C19H20N2O3S | A thiazolidinedione used adjunctively with diet and exercise to normalize glycemic levels in adults with type 2 diabetes mellitus. | Peroxisome Proliferator Receptor gamma Agonist / Thiazolidinediones | |
Methylnaltrexone | 356.441 C21H26NO4 | A μ-opioid antagonist used for the treatment of opioid-induced constipation in palliative patients that are inadequately responding to laxative therapy. | Peripheral Opioid Receptor Antagonists | |
Vamorolone | 356.462 C22H28O4 | A synthetic glucocorticoid used as an anti-inflammatory and immunosuppressant in the management of Duchenne muscular dystrophy (DMD). | Anti-Inflammatory Agents | |
Estradiol valerate | 356.4984 C23H32O3 | An estradiol prodrug used to treat some effects of menopause, hypoestrogenism, androgen dependant carcinoma of the prostate, and in combination products for endometriosis and contraception. | Estradiol Congeners / Estradiol, agonists / Estrenes / Estrogens | |
Dopexamine | 356.5017 C22H32N2O2 | Dopexamine has been used in trials studying the diagnostic and treatment of Free Flap, Oral Cancer, Hypotension, Septic Shock, and Head and Neck Cancer. | Adrenergic and Dopaminergic Agents | |
Silver sulfadiazine | 357.137 C10H9AgN4O2S | A topical sulfonamide antibiotic that acts on the bacterial cell wall and cell membrane; approved for the treatment of burns. | Sulfonamides | |
Balsalazide | 357.3175 C17H15N3O6 | An aminosalicylate used to treat ulcerative colitis. | Salicylates | |
Cinacalcet | 357.412 C22H22F3N | A calcium sensing receptor agonist used to treat secondary hyperparathyroidism in chronic kidney disease and hypercalcemia in parathyroid carcinoma. | Calcimimetic Agents / Calcium-Regulating Hormones and Agents / Calcium-sensing Receptor Agonist / Naphthalenes | |
Rosiglitazone | 357.427 C18H19N3O3S | A thiazolidinedione indicated as an adjunct to diet and exercise to maintain glycemic control in type 2 diabetes. | Peroxisome Proliferator Receptor gamma Agonist / Thiazolidinediones / Vasodilating Agents | |
Nalbuphine | 357.4434 C21H27NO4 | An opioid agonist-antagonist used to treat pain, for pre and postoperative analgesia, and for analgesia in labor and delivery. | Morphinan Derivatives / Opioid Antagonists | |
Oxybutynin | 357.4864 C22H31NO3 | An antimuscarinic agent that reduces detrusor muscle activity, relaxing the bladder and preventing the urge to void. | Drugs for Urinary Frequency and Incontinence | |
Indomethacin | 357.788 C19H16ClNO4 | A nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants. | Acetic Acid Derivatives and Related Substances / Antiinflammatory Preparations, Non-Steroids for Topical Use | |
Bendamustine | 358.263 C16H21Cl2N3O2 | An antineoplastic agent used for the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed following rituximab therapy. | Nitrogen Mustard Analogues | |
Fezolinetant | 358.4 C16H15FN6OS | A non-hormonal drug used to treat moderate to severe vasomotor symptoms due to menopause. | Cytochrome P-450 CYP1A2 Substrates / Cytochrome P-450 CYP2C19 Substrates / Cytochrome P-450 CYP2C9 Substrates / Cytochrome P-450 Substrates / Genito Urinary System and Sex Hormones / Heterocyclic Compounds, Fused-Ring / Neurokinin 3 Receptor Antagonist / Sulfur Compounds / Thiazoles | |
Prednisone | 358.4281 C21H26O5 | A corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases. | Corticosteroids Acting Locally / Glucocorticoids | |
Florbetaben F-18 | 358.444 C21H26FNO3 | A radiopharmaceutical diagnostic agent used during Positron Emission Tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients to diagnose the causes of cognitive impairment. | Fluorine Radioisotopes / Radioactive Diagnostic Agent | |
Cilastatin | 358.453 C16H26N2O5S | A renal dehydropeptidase inhibitor used to prevent degradation of imipenem. Both medications are used together to treat a variety of infections. | Cyclopropanes / Protease Inhibitors / Renal Dehydropeptidase Inhibitor | |
Canrenoic acid | 358.478 C22H30O4 | An aldosterone antagonist used in primary hyperaldosteronism and other disorders related to aberrant aldosterone levels. | Mineralocorticoid Receptor Antagonists |
Displaying drugs 1576 - 1600 of 2778 in total