| DB04348 | Taurocholic acid | The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats... |
| DB02659 | Cholic Acid | A bile acid used for the treatment of bile acid synthesis disorders due to single enzyme defects and as an adjunctive treatment of peroxisomal disorders with disrupted liver function. |
| DB01045 | Rifampicin | An antibiotic used to treat several types of mycobacterial infections including Mycobacterium avium complex, leprosy, and in combination with other antibacterials to treat latent or active tuberculosis. |
| DB00286 | Conjugated estrogens | A mixture of estrogens used in estrogen replacement therapy for menopause and hypoestrogenism, used in the treatment of various malignancies, and used in the treatment of postmenopausal osteoporosis. |
| DB00655 | Estrone | An estrogen used to treat perimenopausal and postmenopausal symptoms. |
| DB00783 | Estradiol | An estrogenic steroid used to treat vasomotor symptoms of vulvar and vaginal atrophy in menopause, hypoestrogenism, prevention of postmenopausal osteoarthritis, treatment of breast cancer, and advanced androgen-dependent carcinoma of the prostate. |
| DB01232 | Saquinavir | An HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency. |
| DB00503 | Ritonavir | An HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection. |
| DB00220 | Nelfinavir | A viral protease inhibitor used in the treatment of HIV infection. |
| DB00224 | Indinavir | A protease inhibitor used to treat HIV infection. |
| DB01892 | Hyperforin | Hyperforin is a phytochemical generated by the plants of the Hypericum family. One of the most important members of this family, due to its medical properties, is Hypericum perforatum, also... |
| DB00091 | Cyclosporine | A steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis. |
| DB00908 | Quinidine | A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias. |
| DB00345 | Aminohippuric acid | A hippuric acid derivative injection utilized in the measurement of effective renal plasma flow (ERPF) and functional capacity of the renal excretory system. |
| DB00583 | Levocarnitine | A quaternary ammonium compound used to treat carnitine deficiency or to stimulate gastric and pancreatic secretions in hyperlipoproteinemia. |
| DB00877 | Sirolimus | An immunosuppressant used to prevent organ transplant rejections and to treat lymphangioleiomyomatosis. |
| DB00641 | Simvastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular events including myocardial infarction and stroke. |
| DB00227 | Lovastatin | An HMG-CoA reductase inhibitor used to lower LDL cholesterol and reduce the risk of cardiovascular disease and associated conditions, including myocardial infarction and stroke. |
| DB01076 | Atorvastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. |
| DB00197 | Troglitazone | For the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise. |
| DB00412 | Rosiglitazone | A thiazolidinedione indicated as an adjunct to diet and exercise to maintain glycemic control in type 2 diabetes. |
| DB01132 | Pioglitazone | A thiazolidinedione used to treat hyperglycemia in type 2 diabetes mellitus. |
| DB00762 | Irinotecan | An antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum. |
| DB00520 | Caspofungin | An echinocandin used to treat a variety of fungal infections. |
| DB01393 | Bezafibrate | A lipid-lowering fibrate used in the management of primary and secondary hyperlipidaemia, when there is a lack of clinical improvement following lifestyle modifications or correction of the underlying disorder. |
| DB01241 | Gemfibrozil | A lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia. |
| DB06151 | Acetylcysteine | A medication that can be used as a mucolytic in patients with certain lung conditions and as an antidote for acetaminophen overdose. |
| DB04881 | Elacridar | For the treatment of solid tumors. |
| DB06191 | Zosuquidar | Investigated for use/treatment in leukemia (myeloid) and myelodysplastic syndrome. |
| DB00661 | Verapamil | A calcium channel blocker used for the short-term treatment of angina, arrhythmia, and hypertension. |
| DB00213 | Pantoprazole | A proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid. |
| DB00390 | Digoxin | A cardiac glycoside used in the treatment of mild to moderate heart failure and for ventricular response rate control in chronic atrial fibrillation. |
| DB06210 | Eltrombopag | A thrombopoietin receptor agonist used to treat thrombocytopenia or aplastic anemia associated with various etiologies. |
| DB06589 | Pazopanib | An antineoplastic agent used in the treatment of advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy. |
| DB06772 | Cabazitaxel | An antineoplastic agent used for the treatment of hormone-refractory metastatic prostate cancer previously treated with a docetaxel-containing treatment regimen. |
| DB08864 | Rilpivirine | A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1). |
| DB08912 | Dabrafenib | A kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer. |
| DB06290 | Simeprevir | A direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4. |
| DB04850 | Posizolid | For the treatment of gram-positive infections, including multiresistant strains. |
| DB09054 | Idelalisib | An antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL). |
| DB09272 | Eluxadoline | A mixed mu-opioid receptor agonist used to treat irritable bowel syndrome with diarrhea. |
| DB09292 | Sacubitril | A neprilysin inhibitor used in combination with valsartan as an adjunct to reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. |
| DB09102 | Daclatasvir | A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. |
| DB11613 | Velpatasvir | A NS5A inhibitor used to treat chronic hepatitis C infections in patients without cirrhosis or with compensated cirrhosis. |
| DB05521 | Telaprevir | An NS3/4A viral protease inhibitor used in combination with other antivirals for the curative treatment of chronic Hepatitis C Virus infections. |
| DB09198 | Lobeglitazone | Lobeglitazone was approved by the Ministry of Food and Drug Safety (South Korea) in 2013, and is being monitored by postmarketing surveillance until 2019. Lobeglitazone is not approved for use... |
| DB12026 | Voxilaprevir | A nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections. |
| DB13874 | Enasidenib | An isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation. |
| DB13878 | Pibrentasvir | A Hepatitis C NS5A inhibitor used to treat Hepatitis C. |
| DB13879 | Glecaprevir | A Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C. |
| DB12332 | Rucaparib | An anti-cancer agent used to treat recurrent ovarian, fallopian tube, or peritoneal cancer. |
| DB13952 | Estradiol acetate | An estrogen used to treat vasomotor symptoms and moderate to severe vulvar and vaginal atrophy from menopause. |
| DB13953 | Estradiol benzoate | Estradiol benzoate is not currently available in any FDA or Health Canada approved products. |
| DB13954 | Estradiol cypionate | An estradiol prodrug used to treat vasomotor symptoms and hypoestrogenisms from hypogonadism. |
| DB13955 | Estradiol dienanthate | Estradiol dienanthate is not currently available in any FDA or Health Canada approved products. |
| DB13956 | Estradiol valerate | An estradiol prodrug used to treat some effects of menopause, hypoestrogenism, androgen dependant carcinoma of the prostate, and in combination products for endometriosis and contraception. |
| DB01072 | Atazanavir | An antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV. |
| DB00199 | Erythromycin | A macrolide antibiotic used to treat and prevent a variety of bacterial infections. |
| DB00439 | Cerivastatin | A statin (or HMG CoA reductase inhibitor) used with dietary changes to decrease lipid levels and reduce the risk of cardiovascular events. |
| DB01092 | Ouabain | For the treatment of atrial fibrillation and flutter and heart failure |
| DB00177 | Valsartan | An angiotensin-receptor blocker used to manage hypertension alone or in combination with other antihypertensive agents and to manage heart failure in patients who are intolerant to ACE inhibitors. |
| DB00451 | Levothyroxine | A synthetic T4 hormone used to treat hypothyroidism that can be used along with surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer. |
| DB01095 | Fluvastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. |
| DB08860 | Pitavastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. |
| DB06626 | Axitinib | An oral VEGFR and kinase inhibitor used for the treatment of advanced renal cell carcinoma after failure of one prior systemic therapy. |
| DB01098 | Rosuvastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. |
| DB09297 | Paritaprevir | A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections. |
| DB00975 | Dipyridamole | A phosphodiesterase inhibitor used to prevent postoperative thromboembolic events. |
| DB00541 | Vincristine | A vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. |
| DB12319 | Benzbromarone | Benzbromarone has been used in trials studying the basic science and treatment of Heart Failure, Hyperuricemia, Chronic Kidney Disease, Abnormal Renal Function, and Gout and Asymptomatic Hyperuricemia. |
| DB08862 | Cholecystokinin | For use as a diagnostic aid for evaluation of gallbladder disorders. It is also used in conjunction with secretin in pancreatic insufficiency . |
| DB00255 | Diethylstilbestrol | Used in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery. |
| DB01645 | Genistein | Currently Genistein is being studied in clinical trials as a treatment for prostate cancer. |
| DB00602 | Ivermectin | An anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis. |
| DB01115 | Nifedipine | A dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension. |
| DB01051 | Novobiocin | For the treatment of infections due to staphylococci and other susceptible organisms |
| DB00646 | Nystatin | A polyene antifungal used to treat cutaneous and mucocutaneous mycotic infections. |
| DB11869 | Valspodar | Valspodar has been used in trials studying the treatment of Cancer, Sarcoma, Leukemia, Lymphoma, and Breast Cancer, among others. |
| DB00206 | Reserpine | Foe the treatment of hypertension |
| DB09298 | Silibinin | Currently being tested as a treatment of severe intoxications with hepatotoxic substances, such as death cap (Amanita phalloides) poisoning. |
| DB00795 | Sulfasalazine | An anti-inflammatory drug used to treat Crohn's disease and rheumatoid arthritis. |
| DB00932 | Tipranavir | A protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor. |
| DB01601 | Lopinavir | An HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV). |
| DB01264 | Darunavir | A HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies. |
| DB00328 | Indomethacin | A nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants. |
| DB00701 | Amprenavir | A protease inhibitor used to treat HIV infection. |
| DB00586 | Diclofenac | An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. |
| DB04216 | Quercetin | Quercetin is a flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin. |
| DB00622 | Nicardipine | A calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina. |
| DB00396 | Progesterone | A hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia. |
| DB00570 | Vinblastine | A vinca alkaloid used to treat breast cancer, testicular cancer, neuroblastoma, Hodgkin's and non-Hodgkins lymphoma, mycosis fungoides, histiocytosis, and Kaposi's sarcoma. |
| DB00468 | Quinine | An alkaloid used to treat uncomplicated Plasmodium falciparum malaria. |
| DB01026 | Ketoconazole | A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections. |
| DB13919 | Candesartan | Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is available as a prodrug in the form of Candesartan cilexetil. |
| DB09065 | Cobicistat | A CYP3A inhibitor used to increase the systemic exposure of atazanavir or darunavir in combination with other antiretroviral agents in the treatment of HIV-1 infection. |
| DB00976 | Telithromycin | An ketolide used to treat community acquired pneumonia of mild to moderate severity. |
| DB01590 | Everolimus | A mammalian target of rapamycin (mTOR) kinase inhibitor used to treat various types of malignancies. |
| DB00203 | Sildenafil | A phosphodiesterase inhibitor used for the treatment of erectile dysfunction. |
| DB00864 | Tacrolimus | A calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis. |
| DB00398 | Sorafenib | A kinase inhibitor used in the treatment of unresectable liver carcinoma and advanced renal carcinoma. |
| DB04868 | Nilotinib | A kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib. |
| DB11586 | Asunaprevir | Asunaprevir is indicated in combination with other agents for the treatment of chronic hepatitis C in adult patients with hepatitis C virus genotypes 1 or 4 and compensated liver cirrhosis.... |
| DB13867 | Fluticasone | Fluticasone's 2 esters are indicated as inhalers for the treatment and management of asthma by prophylaxis[FDA Label] as well as inflammatory and pruritic dermatoses . A DB00588 nasal spray is... |
| DB08906 | Fluticasone furoate | An inhaled corticosteroid that can be used as maintenance treatment of asthma and/or chronic obstructive pulmonary disease (COPD) depending on the product. Also available as a nasal spray to manage symptoms of allergic rhinitis. |
| DB00588 | Fluticasone propionate | A glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis. |
| DB09078 | Lenvatinib | A receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma. |
| DB05928 | Dovitinib | Investigated for use/treatment in multiple myeloma and solid tumors. |
| DB08880 | Teriflunomide | A pyrimidine synthesis inhibitor with anti-inflammatory and immunomodulatory properties used to treat patients with the relapsing-remitting form of multiple sclerosis. |
| DB02703 | Fusidic acid | A topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria. |
| DB00778 | Roxithromycin | Used to treat respiratory tract, urinary and soft tissue infections. |
| DB11753 | Rifamycin | An antibacterial used to treat traveler's diarrhea. |
| DB11581 | Venetoclax | A BCL-2 inhibitor used to treat chronic lymphocytic leukemia, small lymphocytic lymphoma, or acute myeloid leukemia. |
| DB00834 | Mifepristone | A cortisol receptor blocker used to treat Cushing's syndrome, and to terminate pregnancies up to 70 days gestation. |
| DB00257 | Clotrimazole | A topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis. |
| DB00394 | Beclomethasone dipropionate | An inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks. |
| DB12978 | Pexidartinib | An antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor. |
| DB12500 | Fedratinib | Fedratinib is indicated to treat adults with primary or secondary myelofibrosis that is either intermediate-2 or high risk. |
| DB11757 | Istradefylline | A selective adenoside A2A receptor antagonist indicated in adjunct to levodopa and carbidopa for the treatment of Parkinson's Disease. |
| DB04855 | Dronedarone | An antiarrhythmic agent used in the reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation. |
| DB15444 | Elexacaftor | Elexacaftor, in combination with ivacaftor and tezacaftor as the combination product TrikaftaTM, is indicated for the treatment of cystic fibrosis (CF) in patients 12 years of age and older who... |