Enzyme Inhibitors

All categories
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
DrugDrug NameDrug Indication
DB00001LepirudinFor the treatment of heparin-induced thrombocytopenia
DB00006BivalirudinFor treatment of heparin-induced thrombocytopenia and for the prevention of thrombosis. Bivalirudin is indicated for use in patients undergoing percutaneous coronary intervention (PCI), in patients at moderate to high risk acute coronary syndromes due to unstable angina or non-ST segment elevation in whom a PCI is planned.
DB00058Alpha-1-proteinase inhibitorFor chronic augmentation and maintenance therapy in individuals with alpha1-proteinase inhibitor (A1-PI) deficiency and clinical evidence of emphysema.
DB00091CiclosporinFor treatment of transplant (kidney, liver, and heart) rejection, rheumatoid arthritis, severe psoriasis.
DB00175PravastatinFor the treatment of hypercholesterolemia and to reduce the risk of cardiovascular disease.
DB00176FluvoxamineIndicated predominantly for the management of depression and for Obsessive Compulsive Disorder (OCD) [FDA Label]. Has also been used in the management of bulimia nervosa [A250].
DB00178RamiprilFor the management of mild to severe hypertension. May be used to reduce cardiovascular mortality following myocardial infarction in hemodynamically stable individuals who develop clinical signs of congestive heart failure within a few days following myocardial infarction. To reduce the rate of death, myocardial infarction and stroke in individuals at high risk of cardiovascular events. May be used to slow the progression of renal disease in individuals with hypertension, diabetes mellitus and microalubinuria or overt nephropathy.
DB00179MasoprocolUsed for the treatment of actinic keratoses (precancerous skin growths that can become malignant if left untreated).
DB00190CarbidopaFor treatment of the symptoms of idiopathic Parkinson's disease (paralysis agitans), post-encephalitic parkinsonism
DB00196FluconazoleFor the treatment of fungal infections.
DB00198OseltamivirOseltamivir (Tamiflu) is for the treatment of uncomplicated acute illness due to influenza infection in patients 1 year and older who have been symptomatic for no more than 2 days. It is also used for the prophylaxis of influenza in adult patients and adolescents 13 years and older.
DB00199ErythromycinFor use in the treatment of infections caused by susceptible strains of microorganisms in the following diseases: respiratory tract infections (upper and lower) of mild to moderate degree, pertussis (whooping cough), as adjunct to antitoxin in infections due to Corynebacterium diphtheriae, in the treatment of infections due to Corynebacterium minutissimum, intestinal amebiasis caused by Entamoeba histolytica, acute pelvic inflammatory disease caused by Neisseria gonorrhoeae, skin and soft tissue infections of mild to moderate severity caused by Streptococcus pyogenes and Staphylococcus aureus, primary syphilis caused by Treponema pallidum, infections caused by Chlamydia trachomatis, nongonococcal urethritis caused by Ureaplasma urealyticum, and Legionnaires' disease caused by Legionella pneumophila.
DB00201CaffeineFor management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
DB00203SildenafilFor the treatment of erectile dysfunction and to relieve symptoms of pulmonary arterial hypertension (PAH).
DB00205PyrimethamineFor the treatment of toxoplasmosis and acute malaria; For the prevention of malaria in areas non-resistant to pyrimethamine
DB00208TiclopidineUsed in patients, who have had a stroke or stroke precursors and who cannot take aspirin or aspirin has not worked, to try to prevent another thrombotic stroke.
DB00212RemikirenFor the treatment of hypertension and heart failure
DB00213PantoprazoleShort-term (up to 16 weeks) treatment of erosive esophagitis.
DB00218MoxifloxacinFor the treatment of sinus and lung infections such as sinusitis, pneumonia, and secondary infections in chronic bronchitis. Also for the treatment of bacterial conjunctivitis (pinkeye).
DB00220NelfinavirUsed in combination with other antiviral drugs in the treatment of HIV in both adults and children.
DB00224IndinavirIndinavir is an antiretroviral drug for the treatment of HIV infection.
DB00227LovastatinFor management as an adjunct to diet to reduce elevated total-C, LDL-C, apo B, and TG levels in patients with primary hypercholesterolemia and mixed dyslipidemia. For primary prevention of coronary heart disease and to slow progression of coronary atherosclerosis in patients with coronary heart disease.
DB00235MilrinoneIndicated for the treatment of congestive heart failure.
DB00238NevirapineFor use in combination with other antiretroviral drugs in the ongoing treatment of HIV-1 infection.
DB00249IdoxuridineFor use in keratoconjunctivitis and keratitis caused by herpes simplex virus.
DB00250DapsoneFor the treatment and management of leprosy and dermatitis herpetiformis.
DB00257ClotrimazoleFor the local treatment of oropharyngeal candidiasis and vaginal yeast infections, also used in fungal infections of the skin such as ringworm, athlete's foot, and jock itch.
DB00266DicoumarolFor decreasing blood clotting. Often used along with heparin for treatment of deep vein thrombosis.
DB00277TheophyllineFor the treatment of the symptoms and reversible airflow obstruction associated with chronic asthma and other chronic lung diseases, such as emphysema and chronic bronchitis.
DB00278ArgatrobanArgatroban is indicated for prevention and treatment of thrombosis caused by heparin induced thrombocytopenia (HIT). It is also indicated for use in patients with, or at risk for, HIT who are undergoing percutaneous coronary intervention.
DB00284AcarboseFor treatment and management of diabetes type II (used in combination therapy as a second or third line agent)
DB00293RaltitrexedFor the treatment of malignant neoplasm of colon and rectum
DB00300Tenofovir disoproxilTenofovir is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients 2 years of age and older. It is also indicated for the treatment of chronic hepatitis B in adults and pediatric patients 12 years of age and older.
DB00305MitomycinFor treatment of malignant neoplasm of lip, oral cavity, pharynx, digestive organs, peritoneum, female breast, and urinary bladder. Also used as an adjunct to ab externo glaucoma surgery.
DB00311EthoxzolamideFor use in the treatment of duodenal ulcers, as a diuretic, and in the treatment of glaucoma, and may also be useful in the treatment of seizures associated with epilepsy.
DB00313Valproic AcidFor treatment and management of seizure disorders, mania, and prophylactic treatment of migraine headache. In epileptics, valproic acid is used to control absence seizures, tonic-clonic seizures (grand mal), complex partial seizures, and the seizures associated with Lennox-Gastaut syndrome.
DB00314CapreomycinUsed in the treatment of tuberculosis in combination with other drugs.
DB00317GefitinibFor the continued treatment of patients with locally advanced or metastatic non-small cell lung cancer after failure of either platinum-based or docetaxel chemotherapies.
DB00323TolcaponeUsed as an adjunct to levodopa/carbidopa therapy for the symptomatic treatment of Parkinson's Disease. This drug is generally reserved for patients with parkinsonian syndrome receiving levodopa/carbidopa who are experiencing symptom fluctuations and are not responding adequately to or are not candidates for other adjunctive therapies.
DB00328IndometacinFor moderate to severe rheumatoid arthritis including acute flares of chronic disease, ankylosing spondylitis, osteoarthritis, acute painful shoulder (bursitis and/or tendinitis) and acute gouty arthritis.
DB00337PimecrolimusFor treatment of mild to moderate atopic dermatitis.
DB00338OmeprazoleOmeprazole is indicated for the treatment of duodenal ulcers, benign gastric ulcers, gastroesophageal reflux disease (GERD), heartburn and other symptoms associated with GERD, erosive esophagitis, and long-term treatment of pathological hypersecretory conditions like Zollinger-Ellison syndrome, multiple endocrine adenomas, and systemic mastocytosis.
DB00348NitisinoneUsed as an adjunct to dietary restriction of tyrosine and phenylalanine in the treatment of hereditary tyrosinemia type 1.
DB00357AminoglutethimideFor the suppression of adrenal function in selected patients with Cushing's syndrome, malignant neoplasm of the female breast, and carcinoma in situ of the breast.
DB00365GrepafloxacinFor treatment of adults with mild to moderate infections caused by susceptible strains of Haemophilus influenzae, Streptococcus pneumoniae, or Moraxella catarrhalis.
DB00380DexrazoxaneFor reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin hydrochloride dose of 300 mg/m^2 and would benefit from continued doxorubicin therapy. Also approved for the treatment of extravasation from intravenous anthracyclines.
DB00382TacrineFor the palliative treatment of mild to moderate dementia of the Alzheimer's type.
DB00385ValrubicinFor the treatment of cancer of the bladder.
DB00390DigoxinFor the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure.
DB00398SorafenibSorafenib is indicated for the treatment of unresectable hepatocellular carcinoma and advanced renal cell carcinoma.
DB00410MupirocinFor the treatment of Staphylococci nasal carriers.
DB00419MiglustatFor the treatment of adult patients with mild to moderate type 1 (nonneuropathic) Gaucher's disease for whom enzyme replacement therapy is not a therapeutic option (e.g. due to constraints such as allergy, hypersensitivity, or poor venous access). Now approved in some countries for the treatment of progressive neurological symptoms in adult and pediatric patients with Niemann-Pick disease type C (NP-C).
DB00437AllopurinolFor the treatment of hyperuricemia associated with primary or secondary gout. Also indicated for the treatment of primary or secondary uric acid nephropathy, with or without the symptoms of gout, as well as chemotherapy-induced hyperuricemia and recurrent renal calculi.
DB00439CerivastatinUsed as an adjunct to diet for the reduction of elevated total and LDL cholesterol levels in patients with primary hypercholesterolemia and mixed dyslipidemia (Fredrickson Types IIa and IIb) when the response to dietary restriction of saturated fat and cholesterol and other non-pharmacological measures alone has been inadequate.
DB00440TrimethoprimFor the treatment of urinary tract infections, uncomplicated pyelonephritis (with sulfamethoxazole) and mild acute prostatitis. May be used as pericoital (with sulfamethoxazole) or continuous prophylaxis in females with recurrent cystitis. May be used as an alternative to treat asymptomatic bacteriuria during pregnancy (only before the last 6 weeks of pregnancy). Other uses include: alternative agent in respiratory tract infections (otitis, sinusitus, bronchitis and pneumonia), treatment of Pneumocystis jirovecii pneumonia (acute or prophylaxis), Nocardia infections, and traveller's diarrhea.
DB00441GemcitabineGemcitabine is indicated for the treatment of advanced ovarian cancer that has relapsed at least 6 months after completion of platinum-based therapy; metastatic ovarian cancer; inoperable, locally advanced (Stage IIIA or IIIB), or metastatic (Stage IV) non-small cell lung cancer; and locally advanced (nonresectable Stage II or Stage III) or metastatic (Stage IV) adenocarcinoma of the pancreas.
DB00444TeniposideTeniposide is used for the treatment of refractory acute lymphoblastic leukaemia
DB00445EpirubicinFor use as a component of adjuvant therapy in patients with evidence of axillary node tumor involvement following resection of primary breast cancer.
DB00446ChloramphenicolUsed in treatment of cholera, as it destroys the vibrios and decreases the diarrhea. It is effective against tetracycline-resistant vibrios. It is also used in eye drops or ointment to treat bacterial conjunctivitis.
DB00448LansoprazoleFor the treatment of acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevention of gastroinetestinal bleeds with NSAID use.
DB00461NabumetoneFor acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
DB00465KetorolacFor the short-term (~5 days) management of moderately severe acute pain that requires analgesia at the opioid level, usually in a postoperative setting.
DB00467EnoxacinFor the treatment of adults (≥18 years of age) with the following infections caused by susceptible strains of the designated microorganisms: (1) uncomplicated urethral or cervical gonorrhea due to Neisseria gonorrhoeae, (2) uncomplicated urinary tract infections (cystitis) due to Escherichia coli, Staphylococcus epidermidis, or Staphylococcus saprophyticus, and (3) complicated urinary tract infections due to Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, Staphylococcus epidermidis, or Enterobacter cloacae.
DB00469TenoxicamFor the treatment of rheumatoid arthritis, osteoarthritis, backache, and pain.
DB00472FluoxetineLabeled indication include: major depressive disorder (MDD), moderate to severe bulimia nervosa, obsessive-compulsive disorder (OCD), premenstrual dysphoric disorder (PMDD), panic disorder with or without agoraphobia, and combination treatment with olanzapine for treatment-resistant or bipolar I depression. Unlabeled indications include: selective mutism, mild dementia-associated agitation in nonpsychotic patients, post-traumatic stress disorder (PTSD), social anxiety disorder, chronic neuropathic pain, fibromyalgia, and Raynaud's phenomenon.
DB00478RimantadineFor the prophylaxis and treatment of illness caused by various strains of influenza A virus in adults.
DB00482CelecoxibFor the relief and management of osteoarthritis (OA), rheumatoid arthritis (RA), juvenile rheumatoid arthritis (JRA), ankylosing spondylitis, acute pain, primary dysmenorrhea and oral adjunct to usual care for patients with familial adenomatous polyposis [FDA label].
DB00487PefloxacinFor the treatment of uncomplicated gonococcal urethritis in males and for gram-negative-bacterial infections in the gastrointestinal system and the genitourinary tract.
DB00491MiglitolFor use as an adjunct to diet to improve glycemic control in patients with non-insulin-dependent diabetes mellitus (NIDDM) whose hyperglycemia cannot be managed with diet alone.
DB00492FosinoprilFor treating mild to moderate hypertension, use as an adjunct in treating congestive heart failure, and may be used to slow the rate of progression of renal disease in hypertensive individuals with diabetes mellitus and microalbuminuria or overt nephropathy.
DB00494EntacaponeUsed as an adjunct to levodopa / carbidopa in the symptomatic treatment of patients with idiopathic Parkinson's Disease who experience the signs and symptoms of end-of-dose "wearing-off".
DB00495ZidovudineUsed in combination with other antiretroviral agents for the treatment of human immunovirus (HIV) infections.
DB00500TolmetinFor the relief of signs and symptoms of rheumatoid arthritis and osteoarthritis, including the treatment of acute flares long-term management. Also for treatment of juvenile rheumatoid arthritis.
DB00501CimetidineFor the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion.
DB00503RitonavirIndicated in combination with other antiretroviral agents for the treatment of HIV-1 infection.
DB00511AcetyldigitoxinUsed for fast digitalization in congestive heart failure.
DB00519TrandolaprilFor the treatment of mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure (CHF), to improve survival following myocardial infarction (MI) in individuals who are hemodynamically stable and demonstrate symptoms of left ventricular systolic dysfunction or signs of CHF within a few days following acute MI, and to slow progression of renal disease in hypertensive patients with diabetes mellitus and microalbuminuria or overt nephropathy.
DB00529FoscarnetFor the treatment of CMV retinitis in patients with acquired immunodeficiency syndrome (AIDS) and for treatment of acyclovir-resistant mucocutaneous HSV infections in immunocompromised patients.
DB00530ErlotinibFor the treatment of patients with locally advanced or metastatic non-small cell lung cancer after failure of at least one prior chemotherapy regimen. Also for use, in combination with gemcitabine, as the first-line treatment of patients with locally advanced, unresectable or metastatic pancreatic cancer.
DB00533RofecoxibFor the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras.
DB00537CiprofloxacinFor the treatment of the following infections caused by susceptible organisms: urinary tract infections, acute uncomplicated cystitis, chronic bacterial prostatitis, lower respiratory tract infections, acute sinusitis, skin and skin structure infections, bone and joint infections, complicated intra-abdominal infections (used in combination with metronidazole), infectious diarrhea, typhoid fever (enteric fever), uncomplicated cervical and urethral gonorrhea, and inhalational anthrax (post-exposure).
DB00542BenazeprilFor the treatment of hypertension. It may be used alone or in combination with thiazide diuretics.
DB00545PyridostigmineFor the treatment of myasthenia gravis.
DB00551Acetohydroxamic acidUsed, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections.
DB00552PentostatinFor the treatment of hairy cell leukaemia refractory to alpha interferon.
DB00554PiroxicamFor treatment of osteoarthritis and rheumatoid arthritis.
DB00558ZanamivirFor the prevention and treatment of influenza A and B.
DB00563MethotrexateMethotrexate is indicated in the treatment of gestational choriocarcinoma, chorioadenoma destruens and hydatidiform mole. In acute lymphocytic leukemia, methotrexate is indicated in the prophylaxis of meningeal leukemia and is used in maintenance therapy in combination with other chemotherapeutic agents. Methotrexate is also indicated in the treatment of meningeal leukemia. Methotrexate is used alone or in combination with other anticancer agents in the treatment of breast cancer, epidermoid cancers of the head and neck, advanced mycosis fungoides (cutaneous T cell lymphoma), and lung cancer, particularly squamous cell and small cell types. Methotrexate is also used in combination with other chemotherapeutic agents in the treatment of advanced stage non-Hodgkin’s lymphomas. Methotrexate is indicated in the symptomatic control of severe, recalcitrant, disabling psoriasis. Methotrexate is indicated in the management of selected adults with severe, active rheumatoid arthritis (ACR criteria), or children with active polyarticular-course juvenile rheumatoid arthritis.
DB00573FenoprofenFor relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis. Also for the relief of mild to moderate pain.
DB00580ValdecoxibFor the treatment of osteoarthritis and dysmenorrhoea
DB00582VoriconazoleFor the treatment of esophageal candidiasis, invasive pulmonary aspergillosis, and serious fungal infections caused by Scedosporium apiospermum and Fusarium spp.
DB00584EnalaprilFor the treatment of essential or renovascular hypertension and symptomatic congestive heart failure. It may be used alone or in combination with thiazide diuretics.
DB00586DiclofenacFor the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
DB00601LinezolidFor the treatment of bacterial infections caused by susceptible strains of vancomycin resistant Enterococcus faecium, Staphylococcal aureus (methicillin resistant and susceptible strains), Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus agalactiae.
DB00605SulindacFor acute or long-term use in the relief of signs and symptoms of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute painful shoulder (acute subacromial bursitis/supraspinatus tendinitis), and acute gouty arthritis.
DB00614FurazolidoneFor the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms.
DB00616CandoxatrilNot Available
DB00619ImatinibFor the treatment of Philadelphia chromosome positive chronic myeloid leukemia (Ph+ CML), Ph+ acute lymphoblastic leukaemia, myelodysplastic/myeloproliferative diseases, aggressive systemic mastocytosis, hypereosinophilic syndrome and/or chronic eosinophilic leukemia (CEL), dermatofibrosarcoma protuberans, and malignant gastrointestinal stromal tumors (GIST).
DB00620TriamcinoloneFor the treatment of perennial and seasonal allergic rhinitis.
DB00625EfavirenzFor use in combination treatment of HIV infection (AIDS)
DB00641SimvastatinFor the treatment of hypercholesterolemia and for the reduction in the risk of cardiac heart disease mortality and cardiovascular events. It can also be used in adolescent patients for the treatment of heterozygous familial hypercholesterolemia.
DB00642PemetrexedUsed in combination with cisplatin for the treatment of malignant pleural mesothelioma in adults whose disease is unresectable or who otherwise are not candidates for potentially curative surgery. Also used as a monotherapy for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) after prior chemotherapy
DB00649StavudineFor the treatment of human immunovirus (HIV) infections.
DB00651DyphyllineFor relief of acute bronchial asthma and for reversible bronchospasm associated with chronic bronchitis and emphysema.
DB00674GalantamineFor the treatment of mild to moderate dementia of the Alzheimer's type. Has also been investigated in patients with mild cognitive impairment who did not meet the diagnostic criteria for Alzheimer's disease.
DB00677IsoflurophateFor use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia.
DB00685TrovafloxacinFor treatment of infections caused by susceptible strains of the designated microorganisms in uncomplicated urethral gonorrhea in males and endocervical and rectal gonorrhea in females caused by Neisseria gonorrhoeae as well as non gonoccocal urethritis and cervicitis due to Chlamydia trachomatis.
DB00688Mycophenolate mofetilFor the prophylaxis of organ rejection in patients receiving allogeneic renal, cardiac or hepatic transplants. Mycophenolate mofetil should be used concomitantly with cyclosporine and corticosteroids.
DB00691MoexiprilFor the treatment of hypertension.
DB00694DaunorubicinFor remission induction in acute nonlymphocytic leukemia (myelogenous, monocytic, erythroid) of adults and for remission induction in acute lymphocytic leukemia of children and adults.
DB00701AmprenavirFor the treatment of HIV-1 infection in combination with other antiretroviral agents.
DB00703MethazolamideFor treatment of chronic open-angle glaucoma and acute angle-closure glaucoma
DB00705DelavirdineFor the treatment of HIV-1 infection in combination with appropriate antiretroviral agents when therapy is warranted
DB00709LamivudineFor the treatment of HIV infection and chronic hepatitis B (HBV).
DB00711DiethylcarbamazineUsed for the treatment of individual patients with certain filarial diseases including tropical pulmonary eosinophilia, loiasis, and lymphatic filariasis caused by infection with Wuchereria bancrofti, Brugia malayi, or Brugia timori.
DB00712FlurbiprofenFlurbiprofen tablets are indicated for the acute or long-term symptomatic treatment of rheumatoid arthritis, osteorarthritis and anklosing spondylitis. It may also be used to treat pain associated with dysmenorrhea and mild to moderate pain accompanied by inflammation (e.g. bursitis, tendonitis, soft tissue trauma). Topical ophthalmic formulations may be used pre-operatively to prevent intraoperative miosis.
DB00715ParoxetineLabeled indications include: major depressive disorder (MDD), panic disorder with or without agoraphobia, obsessive-compulsive disorder (OCD), social anxiety disorder (social phobia), generalized anxiety disorder (GAD), post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD). Unlabeled indications include: eating disorders, impulse control disorders, vasomotor symptoms of menopause, obsessive-compulsive disorder (OCD) in children, and mild dementia-associated agitation in nonpsychotic individuals. Brisdelle, which consists of paroxetine mesylate is indicated for the treatment of moderate to severe vasomotor symptoms (like hot flashes) associated with menopause.
DB00718Adefovir DipivoxilFor the treatment of chronic hepatitis B in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.
DB00722LisinoprilFor the treatment of hypertension and symptomatic congestive heart failure. May be used in conjunction with thrombolytic agents, aspirin and/or β-blockers to improve survival in hemodynamically stable individuals following myocardial infarction. May be used to slow the progression of renal disease in hypertensive patients with diabetes mellitus and microalbuminuria or overt nephropathy.
DB00736EsomeprazoleFor the treatment of acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevention of gastroinetestinal bleeds with NSAID use.
DB00744ZileutonFor the prophylaxis and chronic treatment of asthma in adults and children 12 years of age and older.
DB00749EtodolacFor acute and long-term management of signs and symptoms of osteoarthritis and rheumatoid arthritis, as well as for the management of pain.
DB00752TranylcypromineFor the treatment of major depressive episode without melancholia.
DB00759TetracyclineUsed to treat bacterial infections such as Rocky Mountain spotted fever, typhus fever, tick fevers, Q fever, rickettsialpox and Brill-Zinsser disease. May be used to treat infections caused by Chlamydiae spp., B. burgdorferi (Lyme disease), and upper respiratory infections caused by typical (S. pneumoniae, H. influenzae, and M. catarrhalis) and atypical organisms (C. pneumoniae, M. pneumoniae, L. pneumophila). May also be used to treat acne. Tetracycline may be an alternative drug for people who are allergic to penicillin.
DB00762IrinotecanFor the treatment of metastatic colorectal cancer (first-line therapy when administered with 5-fluorouracil and leucovorin). Also used in combination with cisplatin for the treatment of extensive small cell lung cancer. Irinotecan is currently under investigation for the treatment of metastatic or recurrent cervical cancer. Also used in combination with fluorouracil and leucovorin for the treatment of patients with metastatic adenocarcinoma of the pancreas after disease progression following gemcitabine-based therapy.
DB00765MetyrosineFor use in the treatment of patients with pheochromocytoma, for preoperative preparation of patients for surgery, management of patients when surgery is contraindicated, and chronic treatment of patients with malignant pheochromocytoma.
DB00766Clavulanic acidFor use with Amoxicillin, clavulanic acid is suitable for the treatment of infections with Staph. aureus and Bacteroides fragilis, or with beta-lactamase producing H. influenzae and E. coli.
DB00772MalathionFor patients infected with Pediculus humanus capitis (head lice and their ova) of the scalp hair.
DB00773EtoposideFor use in combination with other chemotherapeutic agents in the treatment of refractory testicular tumors and as first line treatment in patients with small cell lung cancer. Also used to treat other malignancies such as lymphoma, non-lymphocytic leukemia, and glioblastoma multiforme.
DB00779Nalidixic acidFor the treatment of urinary tract infections caused by susceptible gram-negative microorganisms, including the majority of E. Coli, Enterobacter species, Klebsiella species, and Proteus species.
DB00780PhenelzinePhenelzine is indicated for the treatment of nonendogenous, neurotic or atypical depression for patients that do not tolerate other forms of therapy.[L1356] Atypical depression has a high prevalence rate, starts in early life, tends to last longer, is more likely to occur in people with bipolar disorder, has a high comorbidity with anxiety disorder and carries more risk of suicidal behavior. It is important to specify the atypical feature to predict the clinical course of depression and hence generate the best treatment and service. The featuring symptoms of the atypical feature include mood reactivity, two or more of this symptoms: 1) increased appetite, 2) increased sleep, 3) leaden paralysis and 4) interpersonal rejection sensitivity and should not have melancholic or catatonic features of depression.[A31917] Neurotic depression is a depression of an emotionally unstable person. It is a secondary condition to major personality disorder, neuroses and drug use disorders. Likewise, a primary depression with a family history of depression spectrum disease would fit in this category.[A31922] A nonendogenous depression is characterized by a disturbance in mood and general outlook. The physical symptoms tend to be less severe and it often occurs in response to stressful life events that keep occurring over a large period of time generating a continuous stress in the daily living.[A31924]
DB00784Mefenamic acidFor the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
DB00786MarimastatFor the treatment of various cancers
DB00788NaproxenFor the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, tendinitis, bursitis, and acute gout. Also for the relief of mild to moderate pain and the treatment of primary dysmenorrhea.
DB00790PerindoprilFor the treatment of mild to moderate essential hypertension, mild to moderate congestive heart failure, and to reduce the cardiovascular risk of individuals with hypertension or post-myocardial infarction and stable coronary disease.
DB00798GentamicinFor treatment of serious infections caused by susceptible strains of the following microorganisms: P. aeruginosa, Proteus species (indole-positive and indole-negative), E. coli, Klebsiella-Enterobactor-Serratia species, Citrobacter species and Staphylococcus species (coagulase-positive and coagulase-negative).
DB00806PentoxifyllineFor the treatment of patients with intermittent lameness or immobility arising from chronic occlusive arterial disease of the limbs.
DB00814MeloxicamFor symptomatic treatment of arthritis and osteoarthritis.
DB00819AcetazolamideFor adjunctive treatment of: edema due to congestive heart failure; drug-induced edema; centrencephalic epilepsies; chronic simple (open-angle) glaucoma
DB00820TadalafilUsed for the treatment of erectile dysfunction.
DB00822DisulfiramFor the treatment and management of chronic alcoholism
DB00827CinoxacinFor the treatment of initial and recurrent urinary tract infections in adults caused by the following susceptible microorganisms: Escherichia coli, Proteus mirabilis, Proteus vulgaris, Klebsiella species (including K. pneumoniae), and Enterobacter species.
DB00843DonepezilFor the palliative treatment of mild to moderate dementia of the Alzheimer's type.
DB00857TerbinafineFor the treatment of dermatophyte infections of the toenail or fingernail caused by susceptible fungi. Also for the treatment of tinea capitis (scalp ringworm) and tinea corporis (body ringworm) or tinea cruris (jock itch).
DB00861DiflunisalFor symptomatic treatment of mild to moderate pain accompanied by inflammation (e.g. musculoskeletal trauma, post-dental extraction, post-episiotomy), osteoarthritis, and rheumatoid arthritis.
DB00862VardenafilUsed for the treatment of erectile dysfunction
DB00864TacrolimusFor use after allogenic organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It was first approved by the FDA in 1994 for use in liver transplantation, this has been extended to include kidney, heart, small bowel, pancreas, lung, trachea, skin, cornea, and limb transplants. It has also been used in a topical preparation in the treatment of severe atopic dermatitis.
DB00869DorzolamideFor the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Also used prophylatically for the inhibition of perioperative IOP increase (before neodynium yttrium aluminum garnet laser posterior capsulotomy).
DB00870SuprofenUsed as eye drops to inhibit the miosis (pupil constriction) that may occur during ocular surgery.
DB00879EmtricitabineIndicated, in combination with other antiretroviral agents, for the treatment of HIV-1 infection in adults and for postexposure prophylaxis of HIV infection in health care workers and others exposed occupationally or nonoccupationally via percutaneous injury or mucous membrane or nonintact skin contact with blood, tissues, or other body fluids associated with risk for transmission of the virus.
DB00881QuinaprilFor the treatment of hypertension and as adjunct therapy in the treatment of congestive heart failure. May also be used to slow the rate of progression of renal disease in hypertensive individuals with diabetes mellitus and microalbuminuria or overt nephropathy.
DB00886OmapatrilatFor the treatment of hypertension.
DB00900DidanosineFor use, in combination with other antiretroviral agents, in the treatment of HIV-1 infection in adults.
DB00903Etacrynic acidFor the treatment of high blood pressure and edema caused by diseases like congestive heart failure, liver failure, and kidney failure.
DB00908QuinidineFor the treatment of ventricular pre-excitation and cardiac dysrhythmias
DB00922LevosimendanFor short term treatment of acutely decompensated severe chronic heart failure (CHF). Also being investigated for use/treatment in heart disease.
DB00928AzacitidineFor treatment of patients with the following French-American-British myelodysplastic syndrome subtypes: refractory anemia or refractory anemia with ringed sideroblasts (if accompanied by neutropenia or thrombocytopenia or requiring transfusions), refractory anemia with excess blasts, refractory anemia with excess blasts in transformation (now classified as acute myelogenous leukemia with multilineage dysplasia), and chronic myelomonocytic leukemia.
DB00936Salicylic acidKey additive in many skin-care products for the treatment of acne, psoriasis, callouses, corns, keratosis pilaris and warts.
DB00939Meclofenamic acidFor the relief of mild to moderate pain, for the treatment of primary dysmenorrhea and for the treatment of idiopathic heavy menstrual blood loss. Also for relief of the signs and symptoms of acute and chronic rheumatoid arthritis and osteoarthritis.
DB00943ZalcitabineFor the treatment of Human immunovirus (HIV) infections in conjunction with other antivirals.
DB00944DemecariumFor the topical treatment of chronic open-angle glaucoma.
DB00945Acetylsalicylic acidFor use in the temporary relief of various forms of pain, inflammation associated with various conditions (including rheumatoid arthritis, juvenile rheumatoid arthritis, systemic lupus erythematosus, osteoarthritis, and ankylosing spondylitis), and is also used to reduce the risk of death and/or nonfatal myocardial infarction in patients with a previous infarction or unstable angina pectoris.
DB00955NetilmicinFor the treatment of bacteremia, septicaemia, respiratory tract infections, skin and soft-tissue infection, burns, wounds, and peri-operative infections caused by susceptible strains.
DB00970DactinomycinFor the treatment of Wilms' tumor, childhood rhabdomyosarcoma, Ewing's sarcoma and metastatic, nonseminomatous testicular cancer as part of a combination chemotherapy and/or multi-modality treatment regimen
DB00972AzelastineFor the symptomatic treatment of seasonal allergic rhinitis and non-allergic rhinitis, as well as symptomatic relief of ocular itching associated with allergic conjunctivitis.
DB00975DipyridamoleFor as an adjunct to coumarin anticoagulants in the prevention of postoperative thromboembolic complications of cardiac valve replacement and also used in prevention of angina.
DB00978LomefloxacinFor the treatment of bacterial infections of the respiratory tract (chronic bronchitis) and urinary tract, and as a pre-operative prophylactic to prevent urinary tract infection caused by: S.pneumoniae, H.influenzae, S.aureus, P.aeruginosa, E. cloacae, P. mirabilis, C. civersus, S. asprphyticus, E.coli, and K.pneumoniae.
DB00981PhysostigmineFor the treatment of glaucoma, and in the treatment of severe anticholinergic toxicity.
DB00989RivastigmineFor the treatment of mild to moderate dementia associated with Parkinson's disease or of the Alzheimer's type.
DB00990ExemestaneFor the treatment of advanced breast cancer in postmenopausal women whose disease has progressed following tamoxifen therapy.
DB00994NeomycinTopical uses include treatment for superficial eye infections caused by susceptible bacteria (used in combination with other antiinfectives), treatment of otitis externa caused by susceptible bacteria, treatment or prevention of bacterial infections in skin lesions, and use as a continuous short-term irrigant or rinse to prevent bacteriuria and gram negative rod bacteremia in abacteriuric patients with indwelling catheters. May be used orally to treat hepatic encephalopathy, as a perioperative prophylactic agent, and as an adjunct to fluid and electrolyte replacement in the treatment of diarrhea caused to enteropathogenic E. coli (EPEC).
DB00997DoxorubicinDoxorubicin is used to produce regression in disseminated neoplastic conditions like acute lymphoblastic leukemia, acute myeloblastic leukemia, Wilms’ tumor, neuroblastoma, soft tissue and bone sarcomas, breast carcinoma, ovarian carcinoma, transitional cell bladder carcinoma, thyroid carcinoma, gastric carcinoma, Hodgkin’s disease, malignant lymphoma and bronchogenic carcinoma in which the small cell histologic type is the most responsive compared to other cell types. Doxorubicin is also indicated for use as a component of adjuvant therapy in women with evidence of axillary lymph node involvement following resection of primary breast cancer.
DB01005HydroxyureaFor management of melanoma, resistant chronic myelocytic leukemia, and recurrent, metastatic, or inoperable carcinoma of the ovary and Sickle-cell anemia.
DB01006LetrozoleFor the extended adjuvant treatment of early breast cancer in postmenopausal women who have received 5 years of adjuvant tamoxifen therapy. Also for first-line treatment of postmenopausal women with hormone receptor positive or hormone receptor unknown locally advanced or metastatic breast cancer. Also indicated for the treatment of advanced breast cancer in postmenopausal women with disease progression following antiestrogen therapy.
DB01007TioconazoleFor the local treatment of vulvovaginal candidiasis (moniliasis).
DB01009KetoprofenFor symptomatic treatment of acute and chronic rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, primary dysmenorrhea and mild to moderate pain associated with musculotendinous trauma (sprains and strains), postoperative (including dental surgery) or postpartum pain.
DB01010EdrophoniumFor the differential diagnosis of myasthenia gravis and as an adjunct in the evaluation of treatment requirements in this disease. It may also be used for evaluating emergency treatment in myasthenic crises.
DB01011MetyraponeUsed as a diagnostic drug for testing hypothalamic-pituitary ACTH function. Occasionally used in Cushing's syndrome.
DB01024Mycophenolic acidFor the prophylaxis of organ rejection in patients receiving allogeneic renal transplants, administered in combination with cyclosporine and corticosteroids.
DB01026KetoconazoleFor the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.
DB01030TopotecanFor the treatment of advanced ovarian cancer in patients with disease that has recurred or progressed following therapy with platinum-based regimens. Also used as a second-line therapy for treatment-sensitive small cell lung cancer, as well as in combination with cisplatin for the treatment of stage IV-B, recurrent, or persistent cervical cancer not amenable to curative treatment with surgery and/or radiation therapy.
DB01033MercaptopurineFor remission induction and maintenance therapy of acute lymphatic leukemia.
DB01037SelegilineMonotherapy for initial treatment of Parkinson's disease, as well as an adjunct therapy in patients with a decreased response to levodopa/carbadopa. Also used for the palliative treatment of mild to moderate Alzheimer's disease and at higher doses, for the treatment of depression.
DB01044GatifloxacinFor the treatment of bronchitis, sinusitis, community-acquired pneumonia, and skin infections (abscesses, wounds) caused by S. pneumoniae, H. influenzae, S. aureus, M. pneumoniae, C. pneumoniae, L. pneumophila, S. pyogenes
DB01045RifampicinFor the treatment of Tuberculosis and Tuberculosis-related mycobacterial infections.
DB01048AbacavirFor the treatment of HIV-1 infection, in combination with other antiretroviral agents.
DB01050IbuprofenIbuprofen is the most commonly used and prescribed NSAID. It is very common over the counter medication widely used as an analgesic, anti-inflammatory and antipyretic.[A39096] The use of ibuprofen and its enantiomer [DB09213] in a racemic mix is common for the management of mild to moderate pain related to dysmenorrhea, headache, migraine, postoperative dental pain, spondylitis, osteoarthritis, rheumatoid arthritis, and soft tissue disorder.[A39097] Due to its activity against prostaglandin and thromboxane synthesis, ibuprofen has been attributed to alteration of platelet function and prolongation of gestation and labor.[A39092] As ibuprofen is a widely used medication, the main therapeutic indications are: * Patent Ductus Arteriosus - it is a neonatal condition wherein the ductus arteriosus (blood vessel that connects the main pulmonary artery to the proximal descending aorta) fails to close after birth causing severe risk of heart failure. The prostaglandin inhibition of ibuprofen has been studied for the treatment of this condition as it is known that prostaglandin E2 is responsible for keeping the ductus arteriosus open.[A39100] * Rheumatoid- and osteo-arthritis - ibuprofen is very commonly used in the symptomatic treatment of inflammatory, musculoskeletal and rheumatic disorders.[A39176] * Cystic fibrosis - the use of high dosages of ibuprofen has been proven to decrease inflammation and decreasing polymorphonuclear cell influx in the lungs.[A39177] * Orthostatic hypotension - ibuprofen can induce sodium retention and antagonize the effect of diuretics which has been reported to be beneficial for patients with severe orthostatic hypotension.[A1651] * Dental pain - ibuprofen is used to manage acute and chronic orofacial pain.[A10901] * Minor pain - ibuprofen is widely used to reduce minor aches and pains as well as to reduce fever and manage dysmenorrhea. It is very commonly used for the relief of acute indications such as fever and tension headaches.[A39092] * Investigational uses - efforts have been put into developing ibuprofen for the prophylaxis of Alzheimer's disease, Parkinson disease, and breast cancer.[A39092]
DB01051NovobiocinFor the treatment of infections due to staphylococci and other susceptible organisms
DB01057EchothiophateFor use in the treatment of subacute or chronic angle-closure glaucoma after iridectomy or where surgery is refused or contraindicated.
DB01059NorfloxacinFor the treatment of urinary tract infection
DB01072AtazanavirUsed in combination with other antiretroviral agents for the treatment of HIV-1 infection, as well as postexposure prophylaxis of HIV infection in individuals who have had occupational or nonoccupational exposure to potentially infectious body fluids of a person known to be infected with HIV when that exposure represents a substantial risk for HIV transmission.
DB01073FludarabineFor the treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) who have not responded to or whose disease has progressed during treatment with at least one standard alkylating-agent containing regimen
DB01076AtorvastatinMay be used as primary prevention in individuals with multiple risk factors for coronary heart disease (CHD) and as secondary prevention in individuals with CHD to reduce the risk of myocardial infarction (MI), stroke, angina, and revascularization procedures. May be used to reduce the risk of cardiovascular events in patients with acute coronary syndrome (ACS). May be used in the treatment of primary hypercholesterolemia and mixed dyslipidemia, homozygous familial hypercholesterolemia, primary dysbetalipoproteinemia, and/or hypertriglyeridemia as an adjunct to dietary therapy to decrease serum total and low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (apoB), and triglyceride concentrations, while increasing high-density lipoprotein cholesterol (HDL-C) levels.
DB01078DeslanosideFor the treatment and management of Congestive cardiac insufficiency, arrhythmias and heart failure.
DB01080VigabatrinFor use as an adjunct in treatment resistant epilepsy, refractory complex partial seizures, and secondary generalized seizures. It is also used as monotherapy in infantile spasms in West syndrome.
DB01082StreptomycinFor the treatment of tuberculosis. May also be used in combination with other drugs to treat tularemia (Francisella tularensis), plague (Yersia pestis), severe M. avium complex, brucellosis, and enterococcal endocarditis (e.g. E. faecalis, E. faecium).
DB01083OrlistatFor obesity management including weight loss and weight maintenance when used in conjunction with a reduced-calorie diet. Also used to reduce the risk for weight regain after prior weight loss. Use of orlistat is pending revision due to reports of liver-related adverse events.
DB01092OuabainFor the treatment of atrial fibrillation and flutter and heart failure
DB01095FluvastatinTo be used as an adjunct to dietary therapy to prevent cardiovascular events. May be used as secondary prevention in patients with coronary heart disease (CHD) to reduce the risk of requiring coronary revascularization procedures, for reducing progression of coronary atherosclerosis in hypercholesterolemic patients with CHD, and for the treatment of primary hypercholesterolemia and mixed dyslidipidemia.
DB01097LeflunomideFor the management of the signs and symptoms of active rheumatoid arthritis (RA) to improve physical function and to slow the progression of structural damage associated with the disease. Has also been used for the prevention of acute and chronic rejection in recipients of solid organ trasnplants and is designated by the FDA as an orphan drug for this use.
DB01098RosuvastatinUsed as an adjunct to dietary therapy to treat primary hyperlipidemia (heterozygous familial and nonfamilial), mixed dyslipidemia and hypertriglyceridemia. Also indicated for homozygous familial hypercholesterolemia as an adjunct to other lipid-lowering therapies or when other such therapies are not available. Furthermore, it is used to slow the progression of atherosclerosis and for primary prevention of cardiovascular disease.
DB01103QuinacrineFor the treatment of giardiasis and cutaneous leishmaniasis and the management of malignant effusions.
DB01108TrilostaneUsed in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible.
DB01110MiconazoleFor topical application in the treatment of tinea pedis (athlete’s foot), tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis (moniliasis), and in the treatment of tinea versicolor.
DB01113PapaverineFor the treatment of impotence and vasospasms.
DB01117AtovaquoneFor the treatment or prevention of Pneumocystis carinii pneumonia in patients who are intolerant to trimethoprim-sulfamethoxazole (TMP-SMX). Also indicated for the acute oral treatment of mild to moderate PCP in patients who are intolerant to TMP-SMX.
DB01118AmiodaroneIntravenously, for initiation of treatment and prophylaxis of frequently recurring ventricular fibrillation and hemodynamically unstable ventricular tachycardia in patients refractory to other therapy. Orally, for the treatment of life-threatening recurrent ventricular arrhythmias such as recurrent ventricular fibrillation and recurrent hemodynamically unstable ventricular tachycardia.
DB01122AmbenoniumAmbenonium is used to treat muscle weakness due to muscle disease (myasthenia gravis).
DB01126DutasterideFor the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate gland to improve symptoms, and reduce the risk of acute urinary retention and the need for surgery.
DB01127EconazoleFor topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Microsporum gypseum, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis, and in the treatment of tinea versicolor.
DB01129RabeprazoleFor the treatment of acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevention of gastroinetestinal bleeds with NSAID use.
DB01137LevofloxacinFor the treatment of bacterial conjunctivitis caused by susceptible strains of the following organisms: Corynebacterium species, Staphylococus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus (Groups C/F/G), Viridans group streptococci, Acinetobacter lwoffii, Haemophilus influenzae, Serratia marcescens.
DB01144DiclofenamideFor adjunctive treatment of: chronic simple (open-angle) glaucoma, secondary glaucoma, and preoperatively in acute angle-closure glaucoma where delay of surgery is desired in order to lower intraocular pressure
DB01151DesipramineFor relief of symptoms in various depressive syndromes, especially endogenous depression. It has also been used to manage chronic peripheral neuropathic pain, as a second line agent for the management of anxiety disorders (e.g. panic disorder, generalized anxiety disorder), and as a second or third line agent in the ADHD management.
DB01155GemifloxacinFor the treatment of bacterial infection caused by susceptible strains such as S. pneumoniae, H. influenzae, H. parainfluenzae, or M. catarrhalis, S. pneumoniae (including multi-drug resistant strains [MDRSP]), M. pneumoniae, C. pneumoniae, or K. pneumoniae.
DB01156BupropionFor the treatment of depression and as aid to smoking cessation.
DB01157TrimetrexateFor use, with concurrent leucovorin administration (leucovorin protection), as an alternative therapy for the treatment of moderate-to-severe Pneumocystis carinii pneumonia (PCP) in immunocompromised patients, including patients with the acquired immunodeficiency syndrome (AIDS). Also used to treat several types of cancer including colon cancer.
DB01165OfloxacinFor the treatment of infections (respiratory tract, kidney, skin, soft tissue, UTI), urethral and cervical gonorrhoea.
DB01166CilostazolFor the reduction of symptoms of intermittent claudication (pain in the legs that occurs with walking and disappears with rest).
DB01167ItraconazoleFor the treatment of the following fungal infections in immunocompromised and non-immunocompromised patients: pulmonary and extrapulmonary blastomycosis, histoplasmosis, aspergillosis, and onychomycosis.
DB01171MoclobemideFor the treatment of major depressive disorder and bipolar disorder [A31901].
DB01172KanamycinFor treatment of infections where one or more of the following are the known or suspected pathogens: E. coli, Proteus species (both indole-positive and indole-negative), E. aerogenes, K. pneumoniae, S. marcescens, and Acinetobacter species.
DB01173OrphenadrineIndicated for the treatment of Parkinson's disease.
DB01177IdarubicinFor the treatment of acute myeloid leukemia (AML) in adults. This includes French-American-British (FAB) classifications M1 through M7.
DB01190ClindamycinFor the treatment of serious infections caused by susceptible anaerobic bacteria, including Bacteroides spp., Peptostreptococcus, anaerobic streptococci, Clostridium spp., and microaerophilic streptococci. May be useful in polymicrobic infections such as intra-abdominal or pelvic infections, osteomyelitis, diabetic foot ulcers, aspiration pneumonia and dental infections. May also be used to treat MSSA and respiratory infections caused by S. pneumoniae and S. pyogenes in patients who are intolerant to other indicated antibiotics or who are infected with resistant organism. May be used vaginally to treat vaginosis caused by Gardnerella vaginosa. Clindamycin reduces the toxin producing effects of S. aureus and S. pyogenes and as such, may be particularly useful for treating necrotizing fasciitis. May be used topically to treat acne.
DB01194BrinzolamideFor the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
DB01197CaptoprilFor the treatment of essential or renovascular hypertension (usually administered with other drugs, particularly thiazide diuretics). May be used to treat congestive heart failure in combination with other drugs (e.g. cardiac glycosides, diuretics, β-adrenergic blockers). May improve survival in patients with left ventricular dysfunction following myocardial infarction. May be used to treat nephropathy, including diabetic nephropathy.
DB01204MitoxantroneFor the treatment of secondary (chronic) progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis
DB01207RidogrelUsed as an adjunctive therapy to induce thrombolysis in patients suffering acute myocardial infarction.
DB01208SparfloxacinFor the treatment of adults with the following infections caused by susceptible strains microorganisms: community-acquired pneumonia (caused by Chlamydia pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, Mycoplasma pneumoniae, or Streptococcus pneumoniae) and acute bacterial exacerbations of chronic bronchitis (caused by Chlamydia pneumoniae, Enterobacter cloacae, Haemophilus influenzae, Haemophilus parainfluenzae, Klebsiella pneumoniae, Moraxella catarrhalis, Staphylococcus aureus, or Streptococcus pneumoniae).
DB01211ClarithromycinAn alternative medication for the treatment of acute otitis media caused by H. influenzae, M. catarrhalis, or S. pneumoniae in patients with a history of type I penicillin hypersensitivity. Also for the treatment of pharyngitis and tonsillitis caused by susceptible Streptococcus pyogenes, as well as respiratory tract infections including acute maxillary sinusitis, acute bacterial exacerbations of chronic bronchitis, mild to moderate community-acquired pneuomia, Legionnaires' disease, and pertussis. Other indications include treatment of uncomplicated skin or skin structure infections, helicobacter pylori infection, duodenal ulcer disease, bartonella infections, early Lyme disease, and encephalitis caused by Toxoplasma gondii (in HIV infected patients in conjunction with pyrimethamine). Clarithromycin may also decrease the incidence of cryptosporidiosis, prevent the occurence of α-hemolytic (viridans group) streptococcal endocarditis, as well as serve as a primary prevention for Mycobacterium avium complex (MAC) bacteremia or disseminated infections (in adults, adolescents, and children with advanced HIV infection).
DB01216FinasterideFor the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate to: Improve symptoms, reduce the risk of acute urinary retention, reduce the risk of the need for surgery including transurethral resection of the prostate. Also used for the stimulation of regrowth of hair in men with mild to moderate androgenetic alopecia (male pattern alopecia, hereditary alopecia, common male baldness).
DB01217AnastrozoleFor adjuvant treatment of hormone receptor positive breast cancer , as well as hormonal treatment of advanced breast cancer in post-menopausal women. Has also been used to treat pubertal gynecomastia and McCune-Albright syndrome; however, manufacturer states that efficacy for these indications have not been established.
DB01220RifaximinRifaximin has multiple indications by the FDA: for the treatment of patients (≥12 years of age) with traveller's diarrhea caused by noninvasive strains of Escherichia coli; for the reduction of overt hepatic encephalopathy recurrence in patients ≥18 years of age; and in May 2015 it was approved for irritable bowel syndrome with diarrhea (IBS-D) treatment in adult men and women.
DB01223AminophyllineFor the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.
DB01232SaquinavirFor the treatment of HIV-1 with advanced immunodeficiency together with antiretroviral nucleoside analogues.
DB01241GemfibrozilFor treatment of adult patients with very high elevations of serum triglyceride levels (types IV and V hyperlipidemia) who are at risk of developing pancreatitis (inflammation of the pancreas) and who do not respond adequately to a strict diet.
DB01247IsocarboxazidIsocarboxazid is indicated for the treatment of the enduring and debilitating symptoms of depression that have not responded to other antidepressant drugs.[L1372] Depression is a common but serious mood disorder. The patient will present changes in its feelings, thoughts, and ability to handle everyday activities. For a mood disorder to be considered as depression, the symptoms should be present for at least two weeks.[L1375]
DB01254DasatinibFor the treatment of adults with chronic, accelerated, or myeloid or lymphoid blast phase chronic myeloid leukemia with resistance or intolerance to prior therapy. Also indicated for the treatment of adults with Philadelphia chromosome-positive acute lymphoblastic leukemia with resistance or intolerance to prior therapy.
DB01259LapatinibIndicated in combination with capecitabine for the treatment of patients with advanced or metastatic breast cancer whose tumors overexpress the human epidermal receptor type 2 (HER2) protein and who have received prior therapy including an anthracycline, a taxane, and trastuzuma.
DB01261SitagliptinFor use as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus. Also for use in patients with type 2 diabetes mellitus to improve glycemic control in combination with metformin or a PPARγ agonist (e.g., thiazolidinediones) when the single agent alone, with diet and exercise, does not provide adequate glycemic control.
DB01262DecitabineFor treatment of patients with myelodysplastic syndromes (MDS) including previously treated and untreated, de novo and secondary MDS of all French-American-British subtypes (refractory anemia, refractory anemia with ringed sideroblasts, refractory anemia with excess blasts, refractory anemia with excess blasts in transformation, and chronic myelomonocytic leukemia) and intermediate-1, intermediate-2, and high-risk International Prognostic Scoring System groups (scores ≥0.5).
DB01263PosaconazoleFor prophylaxis of invasive Aspergillus and Candida infections in patients, 13 years of age and older, who are at high risk of developing these infections due to being severely immunocompromised as a result of procedures such as hematopoietic stem cell transplant (HSCT) recipients with graft-versus-host disease (GVHD), or due to hematologic malignancies with prolonged neutropenia from chemotherapy. Also for the treatment of oropharyngeal candidiasis, including oropharyngeal candidiasis refractory to itraconazole and/or fluconazole. Posaconazole is used as an alternative treatment for invasive aspergillosis, Fusarium infections, and zygomycosis in patients who are intolerant of, or whose disease is refractory to, other antifungals.
DB01264DarunavirDarunavir, co-administered with ritonavir, and with other antiretroviral agents, is indicated for the treatment of human immunodeficiency virus (HIV) infection in antiretroviral treatment-experienced adult patients, such as those with HIV-1 strains resistant to more than one protease inhibitor.
DB01265TelbivudineFor the treatment of chronic hepatitis B in adult and adolescent patients ≥16 years of age with evidence of viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.
DB01283LumiracoxibFor the acute and chronic treatment of the signs and symptoms of osteoarthritis of the knee in adults.
DB01319FosamprenavirIndicated in combination with other antiretroviral agents for the treatment of human immunodeficiency virus (HIV-1) infection, as well as postexposure prophylaxis of HIV infection in individuals who have had occupational or nonoccupational exposure to potentially infectious body fluids of a person known to be infected with HIV when that exposure represents a substantial risk for HIV transmission. The use of fosamprenavir is pending revision due to a potential association between the drug and myocardial infarction and dyslipidemia in HIV infected adults.
DB01340CilazaprilCilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure.
DB01348SpiraprilSpirapril is an ACE inhibitor class drug used to treat hypertension.
DB01367RasagilineFor the treatment of the signs and symptoms of idiopathic Parkinsons disease as initial monotherapy and as adjunct therapy to levodopa.
DB01388MibefradilFor the treatment of angina and high blood pressure.
DB01396DigitoxinFor the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure.
DB01397Magnesium salicylateMagnesium salicylate is a common analgesic and non-steroidal anti-inflammatory drug (NSAID) used to treat mild to moderate muscular pain
DB01400NeostigmineNeostigmine is used for the symptomatic treatment of myasthenia gravis by improving muscle tone.
DB01405TemafloxacinFor the treatment of lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections.
DB01427AmrinoneUsed in the treatment of congestive heart failure.
DB01597CilastatinCombined intravenously with imipenem in order to protect it from dehydropeptidase and prolong its antibacterial effect.
DB01601LopinavirIndicated in combination with other antiretroviral agents for the treatment of HIV-infection.
DB01606TazobactamUsed in combination with piperacillin to broaden the spectrum of piperacillin antibacterial action.
DB01611HydroxychloroquineFor the suppressive treatment and treatment of acute attacks of malaria due to Plasmodium vivax, P. malariae, P. ovale, and susceptible strains of P. falciparum. It is also indicated for the treatment of discoid and systemic lupus erythematosus, and rheumatoid arthritis.
DB01626PargylineFor the treatment of moderate to severe hypertension.
DB01627LincomycinLincomycin is an antibiotic used in the treatment of staphylococcal, streptococcal, and Bacteroides fragilis infections.
DB01628EtoricoxibFor the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout.
DB01645GenisteinCurrently Genistein is being studied in clinical trials as a treatment for prostate cancer.
DB01683ChymostatinNot Available
DB01686N,N-dimethylarginineNot Available
DB01791PiclamilastNot Available
DB01816CastanospermineNot Available
DB019337-HydroxystaurosporineNot Available
DB01954RolipramNot Available
DB02010StaurosporineNot Available
DB02020AlrestatinNot Available
DB02044N-(3-(Aminomethyl)Benzyl)AcetamidineNot Available
DB02054GabaculineNot Available
DB02079Aminooxyacetic acidNot Available
DB021053,5-DinitrocatecholNot Available
DB02115DaidzinNot Available
DB02116OlomoucineNot Available
DB02152K-252aNot Available
DB022077-NitroindazoleNot Available
DB02255GM6001Not Available
DB022825'-Deoxy-5'-MethylthioadenosineNot Available
DB023651,10-PhenanthrolineNot Available
DB02383TolrestatFor the pharmacological control of certain diabetic complications.
DB02424GeldanamycinNot Available
DB02430Trehalose-6-PhosphateNot Available
DB02546VorinostatFor the treatment of cutaneous manifestations in patients with cutaneous T-cell lymphoma who have progressive, persistent or recurrent disease on or following two systemic therapies.
DB02557PhosphoramidonNot Available
DB026014-HydroxyphenylglycineNot Available
DB02656LY-294002Not Available
DB02703Fusidic AcidFor the treatment of bacterial infections.
DB02709ResveratrolBeing investigated for the treatment of Herpes labialis infections (cold sores).
DB02742KifunensineNot Available
DB02757PyrazoleNot Available
DB02823Phosphonoacetic AcidNot Available
DB02855N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-ProlineNot Available
DB02860Calyculin ANot Available
DB02967N-EthylmaleimideNot Available
DB03052DazoxibenNot Available
DB030733-MethoxybenzamideNot Available
DB03127BenzamidineNot Available
DB03206DuvoglustatNot Available
DB03366ImidazoleNot Available
DB03395EnalkirenNot Available
DB03424UbenimexAn adjuvant therapy used for acute and chronic myelonous leukemia, lung cancer and nasopharyngeal cancer. It is also used to treat hypercholesterolaemia.
DB03459Sparfosic acidNot Available
DB03496AlvocidibInvestigated for use/treatment in esophageal cancer, leukemia (lymphoid), lung cancer, liver cancer, and lymphoma (unspecified).
DB035092-(4-Chlorophenyl)-5-QuinoxalinecarboxamideNot Available
DB03516EniluracilFor the treatment of cancer in combination with 5-fluorouracil.
DB03575PhencyclidineNot Available
DB03651Picric acidNot Available
DB03758RadicicolNot Available
DB03796Palmitic AcidNot Available
DB03849CilomilastInvestigated for use/treatment in chronic obstructive pulmonary disease (COPD).
DB03880BatimastatNot Available
DB039551-deoxymannojirimycinNot Available
DB04132S-HexylglutathioneNot Available
DB04222SparsomycinNot Available
DB04223NitroarginineNot Available
DB04267Dipicolinic AcidNot Available
DB04291OxfenicineNot Available
DB04299Maleic AcidNot Available
DB04308D-4-hydroxyphenylglycineNot Available
DB044593,4-DichloroisocoumarinNot Available
DB04513N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideNot Available
DB045282,4-DinitrophenolNot Available
DB04539GlyphosateNot Available
DB04552Niflumic AcidUsed in the treatment of rheumatoid arthritis.
DB04576FleroxacinFleroxacin is a broad-spectrum antimicrobial fluoroquinolone.
DB046045-iodotubercidinNot Available
DB04628AllosamidinNot Available
DB04655MetoprineNot Available
DB04690CamptothecinInvestigated for the treatment of cancer.
DB04743NimesulideFor the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old.
DB04744LawsoneNot Available
DB04812BenoxaprofenNot Available
DB04818IproniazidFor the treatment of depression (originally intended to treat tuberculosis).
DB04820NialamideNot Available
DB04849CediranibFor the treatment of liver cancer, advanced non-small cell lung cancer (NSCLC), advanced colorectal cancer (CRC) and other solid tumors.
DB04864Huperzine AInvestigated for use/treatment in alzheimer's disease.
DB04866HalofuginoneFor the treatment of scleroderma, cancer, and restenosis.
DB04876VildagliptinUsed to reduce hyperglycemia in type 2 diabetes mellitus.
DB04878VogliboseFor the treatment of diabetes. It is specifically used for lowering post-prandial blood glucose levels thereby reducing the risk of macrovascular complications.
DB04879VatalanibUsed in combination with first- and second-line chemotherapy for the treatment of metastatic colorectal cancer and non-small cell lung cancer (NSCLC).
DB04880EnoximoneFor the treatment of congestive heart failure.
DB04898XimelagatranFor the treatment of acute deep vein thrombosis.
DB04912StannsoporfinInvestigated for use/treatment in liver disease, metabolic disease, and pediatric indications.
DB04930PermethrinFor the treatment of infestation with Sarcoptes scabiei (scabies).
DB04950RanpirnaseFor the treatment of various forms of cancer.
DB05015BelinostatBelinostat is indicated for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL) with manageable safety profile. It is a potential alternative therapy for patients who did not experience adequate response to first-line drugs for PTCL. It can be used in patients with baseline thrombocytopenia [A19161].
DB05022AmonafideInvestigated for use/treatment in breast cancer, ovarian cancer, and prostate cancer.
DB05073SRT501Investigated for use/treatment in diabetes mellitus type 2 and neurologic disorders.
DB05088Tiomolibdate ionInvestigated for use/treatment in liver disease and pulmonary fibrosis.
DB05100PrinomastatInvestigated for use/treatment in brain cancer, lung cancer, and prostate cancer.
DB05161ElafinInvestigated for use/treatment in inflammatory disorders (unspecified).
DB05173PTC299Investigated for use/treatment in cancer/tumors (unspecified) and solid tumors.
DB05262OxypurinolIntended for the treatment of congestive heart failure and hyperuricemia.
DB05265EcabetFor the treatment of reflux oesophagitis and peptic ulcer disease.
DB05266IbudilastFor the treatment of multiple sclerosis, asthma, and cerebrovascular disease.
DB05289TarenflurbilInvestigated for use/treatment in alzheimer's disease and prostate cancer.
DB05351DexlansoprazoleIndicated for healing all grades of erosive esophagitis (EE), maintaining and healing of EE and relief of heartburn, and treating heartburn associated with symptomatic non-erosive gastroesophageal reflux disease (GERD).
DB05737Varespladib methylInvestigated for use/treatment in atherosclerosis and coronary artery disease.
DB05812AbirateroneUsed in combination with prednisone for the treatment of metastatic, castration-resistant prostate cancer.
DB06159RubitecanInvestigated for use/treatment in pancreatic cancer, leukemia (unspecified), melanoma, ovarian cancer, and cancer/tumors (unspecified).
DB06160GarenoxacinInvestigated for use/treatment in bacterial infection.
DB06193PixantroneCurrently in Phase III investigation for treatment of relapsed or refractory aggressive non-Hodgkin's lymphoma in patients who have failed two prior lines of therapy. Presently, no standard therapy exists for patients with relapsed or refractory NHL. [2] After first line therapy has been initiated, most patients have received their lifetime limit of doxorubicin and further use of anthracyclines may potentially lead to anthracycline-induced congestive heart failure (CHF). Pixantrone is an attractive alternative as a second line agent, due to its lack of cardiac toxicity. [2] The phase III trial, PIX-R, is ongoing and will compare pixantrone multidrug therapy with an equivalent regimen in patients with diffuse large B-cell lymphoma (the most common type of NHL). Previous study results have also suggested the possibility that pixantrone may be safe and effective in doxorubicin naive patients. In myocardial strips which are doxorubicin naive, pixantrone is taken up to a higher degree than in myocardial strips which are doxorubicin exposed, and once absorbed exhibits redox inactivity. [3] Pixantrone dimaleate has also been investigated as a treatment for acute myelogenous leukemia, diffuse large B-cell lymphoma, follicular lymphoma, metastatic breast cancer, low grade small lymphocytic lymphomas and general metastatic cancers.
DB06195SeliciclibInvestigated for use/treatment in breast cancer, lung cancer, lymphoma (unspecified), multiple myeloma, leukemia (lymphoid), and cancer/tumors (unspecified).
DB06203AlogliptinIndicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
DB06228RivaroxabanRivaroxaban is indicated for the prevention of venous thromboembolic events (VTE) in patients who have undergone total hips replacements and total knee replacement surgery; prevention of stroke and systemic embolism in patients with nonvalvular atrial fibrillation; treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE); to reduce risk of recurrent DVT and/or PE. Rivaroxaban is also indicated, in combination with aspirin, for reducing the risk of major cardiovascular events in patients with chronic coronary artery disease or peripheral artery disease. Due to a lack of safety studies, it is not recommended for use in those under 18 years old. Its use is also not recommended in those with severe renal impairment (<30mL/min).
DB06243EflornithineEflornithine is indicated in the treatment of facial hirsutism (excessive hair growth).
DB06246ExisulindInvestigated for use/treatment in adenomatous polyposis coli, lung cancer, prostate cancer, colon polyps, Barrett's esophagus disease, and pediatric indications.
DB06267UdenafilInvestigated for use/treatment in erectile dysfunction and hypertension.
DB06290SimeprevirIndicated for the treatment of adults with chronic hepatitis C virus (HCV) infection: typically in combination with sofosbuvir in patients with HCV genotype 1 without cirrhosis or with compensated cirrhosis and in combination with peginterferon alfa (Peg-IFN-alfa) and ribavirin (RBV) in patients with HCV genotype 1 or 4 without cirrhosis or with compensated cirrhosis. Resistance: Reduced susceptibility to simeprevir was most commonly associated with the viral NS3 Q80K polymorphism. Amino acid substitutions at NS3 positions S122, R155 and/or D168 are also shown to reduce susceptibility to simeprevir in genotype 1a/b patients.
DB06311DarapladibInvestigated for use/treatment in atherosclerosis.
DB06335SaxagliptinTreatment of type 2 diabetes mellitus to improve glycemic control in combination with other agents or as monotherapy.
DB06358IclaprimInvestigated for use/treatment in bacterial infection, skin infections/disorders, obesity, liver disease, kidney disease, and pneumonia.
DB06406IdraparinuxInvestigated for use/treatment in thrombosis, venous thromboembolism, strokes, heart disease, and atrial fibrillation.
DB06414EtravirineIndicated as an adjunct therapy in the treatment of adult HIV-1 infections resistant to therapy with other NNRTIs and antiretroviral agents.
DB06433TezacitabineInvestigated for use/treatment in colorectal cancer, lung cancer, leukemia (unspecified), and gastric cancer.
DB06436SemaxanibInvestigated for use/treatment in colorectal cancer and lung cancer.
DB06595MidostaurinInvestigated for use/treatment in adult patients with high-risk acute myeloid leukemia (AML) who are FLT3 mutation-positive, agressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematological neoplasm (SM-AHN), or mast cell leukemia (MCL).
DB06603PanobinostatPanobinostat is indicated in the treatment of multiple myeloma in combination with dexamethasone and bortezomib in patients who have received 2 previous treatment regimens including bortezomib and an immunomodulatory agent. This indication is approved by accelerated approval based on progression free survival as of February 23, 2015.
DB06605ApixabanApixaban is to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation. It has also been used to lower the risk of developing venous thrombosis post-orthopedic surgical procedures.
DB06614PeramivirInvestigated for use/treatment in influenza.
DB06626AxitinibUsed in kidney cell cancer and investigated for use/treatment in pancreatic and thyroid cancer.
DB06635OtamixabanInvestigated for use/treatment in thrombosis.
DB06692AprotininFor prophylactic use to reduce perioperative blood loss and the need for blood transfusion in patients undergoing cardiopulmonary bypass in the course of coronary artery bypass graft surgery who are at an increased risk for blood loss and blood transfusion.
DB06693MevastatinNot used therapeutically due to its many side effects.
DB06695Dabigatran etexilateDabigatran is indicated for the prevention of venous thromboembolic events in patients who have undergone elective hip or knee replacement surgery (based on RE-NOVATE, RE-MODEL, and RE-MOBILIZE trials). In 2010, it was approved in the US and Canada for prevention of stroke and systemic embolism in patients with atrial fibrillation (approval based on the RE-LY trial). Contraindications: severe renal impairment (CrCL < 30 ml/min); haemorrhagic manifestations, bleeding diathesis or spontaneous or pharmacologic impairment of haemostasis; lesions at risk of clinically significant bleeding (e.g. extensive cerebral infarction (haemorrhagic or ischemic) in the last 6 months, active peptic ulcer disease); concomitant treatment with P-glycoprotein inhibitors (e.g. oral ketoconazole, verapamil); and those with known hypersensitivity to dabigatran, dabigatran etexilate or any ingredient used in the formulation or component of the container. As of December 2012, dabigatran is contraindicated in patients with mechanical prosthetic heart valves.
DB06704IobenguaneDetection of primary and metastatic pheochromocytoma or neuroblastoma
DB06732beta-NaphthoflavoneNot Available
DB06733Bafilomycin A1Not Available
DB06771BesifloxacinTreatment of bacterial conjunctivitis. Bacterial isolates that are susceptible to besifloxacin include: CDC coryneform group G; Corynebacterium pseudodiphtheriticum; Corynebacterium striatum; Haemophilus influenzae; Moraxella lacunata; Staphylococcus aureus; Staphylococcus epidermidis; Staphylococcus hominis; Staphylococcus lugdunensis; Streptococcus mitis group; Streptococcus oralis; Streptococcus pneumoniae; Streptococcus salivarius*
DB06810PlicamycinFor the treatment of testicular cancer, as well as hypercalcemia and hypercalciuria associated with a variety of advanced forms of cancer.
DB06817RaltegravirFor the treatment of HIV-1 infection in conjunction with other antiretrovirals.
DB06827ViomycinViomycin is an essential component in the drug cocktail currently used to fight infections of Mycobacterium tuberculosis.
DB07232VeliparibNot Available
DB073474-(2-Aminoethyl)Benzenesulfonyl FluorideNot Available
DB07348Brefeldin ANot Available
DB07374AnisomycinNot Available
DB07744Z-Val-Ala-Asp fluoromethyl ketoneNot Available
DB079543-isobutyl-1-methyl-7H-xanthineNot Available
DB079965-(2-methylpiperazine-1-sulfonyl)isoquinolineNot Available
DB08437PuromycinNot Available
DB08439ParecoxibUsed for short term perioperative pain control.
DB085507,8-Dichloro-1,2,3,4-tetrahydroisoquinolineNot Available
DB08626ThiorphanNot Available
DB08836TemocaprilTemocapril is an ACE inhibitor primarily indicated in the treatment of hypertension and congestive heart failure, diabetic nephropathy, and improvement of prognosis for coronary artery diseases (including acute myocardial infarction).
DB08860PitavastatinPitavastatin is used to lower serum levels of total cholesterol, LDL-C, apolipoprotein B, and triglycerides, and raise levels of HDL-C for the treatment of dyslipidemia.
DB08864RilpivirineRilpivirine, in combination with other agents, is indicated for the treatment of HIV-1 infections in antiretroviral treatment-naive patients with HIV-1 RNA ≤100,000 copies/mL and CD4+ cell count >200 cells/mm3.[L1030] The FDA combination therapy approval of rilpivirine and dolutegravir is indicated for adults with HIV-1 infections whose virus is currently suppressed (< 50 copies/ml) on a stable regimen for at least six months, without history of treatment failure and no known substitutions associated to resistance to any of the two components of the therapy.[L1031]
DB08865CrizotinibCrizotinib is used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) that is anaplastic-lymphoma kinase (ALK)-positive as detected by a FDA-approved test.
DB08878AminopterinPrior to its withdrawal, aminopterin was initially used in the treatment of childhood leukemia; specifically to induce remissions. Later, aminopterin was used off-label in the United States to treat psoriasis, yielding dramatic lesion clearing. Aminopterin was later supplanted by methotrexate for treating cancer because of its better therapeutic index. Aminopterin (as well as methotrexate) has also been explored for use as an abortifacient. However, their association with severe congenital malformations and teratogenic effects have become known as fetal aminopterin syndrome.
DB08882LinagliptinLinagliptin is used for the management of type 2 diabetes mellitus.
DB08895TofacitinibFor the treatment of moderate to severe rheumatoid arthritis which is resistant or intolerant to methotrexate therapy. It may also be used as an adjunct to methotrexate therapy, or other non-biologic disease-modifying antirheumatic drugs (DMARDS), when methotrexate alone is not sufficient. Tofacitinib has also been investigated as a preventative therapy for kidney transplant rejections, and as a treatment for psoriasis, ulcerative colitis, and ankylosing spondylitis. It is not to be initiated in patients with a history of chronic or recurrent infections, or in the presence of active infection, even if localized, due to reports of serious and sometimes fatal infections (commonly pneumonia, herpes zoster and urinary tract infections). Use of tofacitinib is also discouraged in those who have been, or are likely to be, exposed to TB. An increased likelihood of exposure may be encountered by traveling to certain areas. In addition, tofacitinib is not to be used in patients with severe hepatic impairment, or low hemoglobin (less than 9g/dL). Cautioned is advised when using tofacitinib in patients at risk of gastrointestinal perforation, and in the elderly who are more susceptible to infection.
DB08901PonatinibPonatinib is indicated for the treatment of adult patients with chronic phase, accelerated phase, or blast phase chronic myeloid leukemia (CML) that is resistant or intolerant to prior tyrosine kinase inhibitor therapy or Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ALL) that is resistant or intolerant to prior tyrosine kinase inhibitor therapy.
DB08905FormestaneFor the treatment of estrogen-receptor positive breast cancer in post-menopausal women.
DB08911TrametinibTrametinib is indicated for the treatment of unresectable or metastatic melanoma with BRAF V600E or V600K mutations, as detected by an FDA-approved test [FDA]. In May 2018, it was approved for use with [DB08912] for the treatment of treat anaplastic thyroid cancer caused by an abnormal BRAF V600E gene [L2726].
DB08912DabrafenibTafinlar is a kinase inhibitor that was initially indicated as a single agent for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E mutation as detected by an FDA-approved test [FDA label]. Tafinlar in combination with [DB08911] is indicated for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations as detected by an FDA-approved test. The use in combination is based on the demonstration of durable response rate. Improvement in disease-related symptoms or overall survival has not been demonstrated for Tafinlar in combination with trametinib [FDA label]. In May 2018, Tafinlar (dabrafenib) and Mekinist ([DB08911]) have been approved in combination to treat anaplastic thyroid cancer caused by an abnormal BRAF V600E gene [L2712].
DB08930DolutegravirDolutegravir is indicated in combination with other antiretroviral agents for the treatment of patients with HIV-1 infection that comply with the characteristics of being adults or children aged 12 years and older and present at least a weight of 40 kg.[A7520] The FDA combination therapy approval of dolutegravir and rilpivirine is indicated for adults with HIV-1 infections whose virus is currently suppressed (< 50 copies/ml) on a stable regimen for at least six months, without history of treatment failure and no known substitutions associated to resistance to any of the two components of the therapy.[L1031]
DB08951IndoprofenNot Available
DB08972FlumequineNot Available
DB08981FenbufenNot Available
DB09039EliglustatEliglustat is indicated for the long-term treatment of type 1 Gaucher disease in patients who are CYP2D6 extensive metabolizers (EMs), intermediate metabolizers (IMs), or poor metabolizers (PMs) in treatment-naive and treatment-experienced adult patients.
DB09054IdelalisibIdelalisib is indicated in the treatment of chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL). For the treatment of relapsed CLL, it is currently indicated as a second-line agent in combination with rituximab in patients for whom rituximab alone would be considered appropriate therapy due to other co-morbidities, while in the treatment of FL and SLL it is intended to be used in patients who have received at least two prior systemic therapies.
DB09060AvibactamAVYCAZ (ceftazidime-avibactam), in combination with metronidazole, is indicated for the treatment of complicated intra-abdominal infections caused by the following susceptible microorganisms: Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Providencia stuartii, Enterobacter cloacae, Klebsiella oxytoca, and Pseudomonas aeruginosa in patients 18 years or older. AVYCAZ is also indicated for the treatment of complicated urinary tract infections including pyelonephritis caused by the following susceptible microorganisms: Escherichia coli, Klebsiella pneumoniae, Citrobacter koseri, Enterobacter aerogenes, Enterobacter cloacae, Citrobacter freundii, Proteus spp., and Pseudomonas aeruginosa in patients 18 years or older.
DB09063CeritinibCeritinib is a kinase inhibitor indicated for the treatment of patients with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) who have progressed on or are intolerant to crizotinib. This indication is approved under accelerated approval based on tumor response rate and duration of response. An improvement in survival or disease-related symptoms has not been established. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trials.
DB09065CobicistatCobicistat is a CYP3A inhibitor indicated to increase systemic exposure of atazanavir or darunavir (once daily dosing regimen) in combination with other antiretroviral agents in the treatment of HIV-1 infection. It is not interchangeable with ritonavir to increase systemic exposure of darunavir 600 mg twice daily, fosamprenavir, saquinavir, or tipranavir due to lack of exposure data. The use of cobicistat is not recommended with darunavir 600 mg twice daily, fosamprenavir, saquinavir or tipranavir. Complex or unknown mechanisms of drug interactions preclude extrapolation of ritonavir drug interactions to certain cobicistat interactions. Cobicistat and ritonavir when administered with either atazanavir or darunavir may result in different drug interactions when used with concomitant medications.
DB09073PalbociclibPalbociclib is indicated in combination with letrozole for the treatment of postmenopausal women with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer as initial endocrine-based therapy for their metastatic disease. This indication is approved under accelerated approval based on progression-free survival (PFS). Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial.
DB09074Olaparib* Indicated for the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer, who are in a complete or partial response to platinum-based chemotherapy. * Indicated as monotherapy in patients with deleterious or suspected deleterious germline BRCA mutated (as detected by an FDA-approved test) advanced ovarian cancer who have been treated with three or more prior lines of chemotherapy. * Indicated for the treatment of patients with germline breast cancer susceptibility gene (BRCA) mutated, human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer, who have been previously treated with chemotherapy.
DB09075EdoxabanEdoxaban is indicated to reduce the risk of stroke and systemic embolism (SE) in patients with nonvalvular atrial fibrillation (NVAF). However, it should not be used in patients with creatinine clearance (CrCL) > 95 mL/min because of increased risk of ischemic stroke compared to warfarin at the highest dose studied (60 mg). It is also indicated for the treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE) following 5-10 days of initial therapy with a parenteral anticoagulant.
DB09078LenvatinibLenvatinib is indicated for the treatment of patients with locally recurrent or metastatic, progressive, radioactive iodine-refractory differentiated thyroid cancer.
DB09079NintedanibNintedanib is indicated for the treatment of idiopathic pulmonary fibrosis (IPF).
DB09093ChlortetracyclineUsed in the manufacuring of medicated animal feeds [FDA Label].
DB09241Methylene blueMethylene blue has several indications in medicine: 1. found to improve the hypotension associated with various clinical states. 2. Antiseptic in urinary tract infections. 3. Improves hypoxia and hyper dynamic circulation in cirrhosis of liver and severe hepatopulmonary syndrome. 4. Results in transient and reproducible improvement in blood pressure and cardiac function in septic shock. 5. Investigated for the treatment of Alzheimer's disease. 6. Treatment of ifofosamide induced neurotoxicity.
DB09244PirlindoleFor the treatment of major depression. It is being studied in the treatment of fibromyalgia pain syndrome. One study determined that the effect of pirlindole on sensorimotor performance while driving a motor vehicle shows many similarities to that of placebo. The drug appears to stimulate the central nervous system, rather than exhibit a sedative effect, like many antidepressants. Because of its selective, reversible inhibition of monoamine oxidase (MAO-A) and short half-life, unpleasant "cheese effects" are avoided. This refers to the effects of consuming tyramine-rich foods, such as cheese while medicated with monoamine oxidase inhibitors, leading to severe headaches and hypertension [L1395]. of The available evidence supports pirlindole as a safe and effective treatment option for the management of depression and fibromyalgia syndrome [L1394].
DB09245ToloxatoneFor the treatment of major depressive disorder.
DB09273DoxofyllineIndicated for the treatment of chronic obstructive pulmonary disease (COPD), bronchial asthma and pulmonary disease with spastic bronchial component.
DB09283TrapidilUsed in the treatment of chronic stable angina [A19770].
DB09324SulbactamSulbactam is currently available in combination products with ampicillin. Within this formulation it is indicated for the treatment of infections due to susceptible strains of the designated microorganisms in the conditions listed below. Skin and Skin Structure Infections caused by beta-lactamase producing strains of Staphylococcus aureus, Escherichia coli, Klebsiella spp. (including K. pneumoniae), Proteus mirabilis, Bacteroides fragilis, Enterobacter spp., and Acinetobacter calcoaceticus. Intra-Abdominal Infections caused by beta-lactamase producing strains of Escherichia coli, Klebsiella spp. (including K. pneumoniae), Bacteroides spp. (including B. fragilis), and Enterobacter spp. Gynecological Infections caused by beta-lactamase producing strains of Escherichia coli, and Bacteroides spp. (including B. fragilis).
DB09330OsimertinibOsimertinib is indicated for the treatment of patients with metastatic epidermal growth factor receptor (EGFR) T790M mutation-positive non-small cell lung cancer (NSCLC), as detected by an FDA- approved test, who have progressed on or after EGFR-TKI therapy.
DB09335AlatrofloxacinNot Available
DB09338MersalylElevated blood pressure, edema [L1577, L1585].
DB09477EnalaprilatEnalaprilat injection is indicated for the treatment of hypertension when oral therapy is not practical.
DB09570IxazomibIxazomib is indicated in combination with lenalidomide and dexamethasone for the treatment of patients with multiple myeloma who have received at least one prior therapy.
DB11390CoumaphosNot Available
DB11397DichlorvosNot Available
DB11450PimobendanNot Available
DB11457RotenoneNot Available
DB11473MetrifonateNot Available
DB11510DeslorelinNot Available
DB11593Isatoic anhydrideNot Available
DB11598Antithrombin III humanAntithrombin III human is a human antithrombin (AT) indicated in patients with hereditary antithrombin deficiency for the treatment and prevention of thromboembolism and prevention of peri-operative and peri-partum thromboembolism
DB11617AclarubicinNot Available
DB11623CandoxatrilatNot Available
DB11632OpicaponeOpicapone is approved as an adjunctive therapy in adults with Parkinson’s disease and end-of-dose motor fluctuations whose symptoms cannot be stabilized on levodopa/dopa decarboxylase inhibitor combinations [L2336].
DB11656RebamipideNot Available
DB11672CurcuminNo approved therapeutic indications.
DB11696RacecadotrilNot Available
DB11760TalazoparibTalazoparib is indicated for the treatment of deleterious or suspected deleterious germline BRCA mutated, HER2 negative locally advanced or metastatic breast cancer in adults [FDA Label].
DB11774PazufloxacinNot Available
DB11783ImidaprilNot Available
DB11792MirodenafilNot Available
DB11793NiraparibNiraparib is indicated for the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in complete or partial response to platinum-based chemotherapy
DB11805SaracatinibNot Available
DB11815TilarginineNot Available
DB11829RuboxistaurinNot Available
DB11830MocetinostatNot Available
DB11841EntinostatNot Available
DB11880Acridine CarboxamideNot Available
DB11892PrulifloxacinNot Available
DB11909VarespladibNot Available
DB11912LanopepdenNot Available
DB119196-O-benzylguanineNot Available
DB11924SafingolNot Available
DB11956DelanzomibNot Available
DB11984LetaxabanNot Available
DB12017OzagrelNot Available
DB12038UlinastatinNot Available
DB12072OrantinibNot Available
DB12082VesnarinoneNot Available
DB12131VinpocetineNot Available
DB12137GSK-256066Not Available
DB12149S-3304Not Available
DB12185ExatecanNot Available
DB12194AtamestaneNot Available
DB12264AtevirdineNot Available
DB12286SimendanNot Available
DB12289DarexabanNot Available
DB12328CantharidinThe only therapeutic use for which cantharidin is currently primarily indicated for is as an active ingredient in topical agents for treating common warts (verruca vulgaris), periungual warts, plantar warts, and molluscum contagiosum [A32891, A32892, F32]. At the same time, such topical cantharidin applications have also been used for a number of off-label indications like callus removal, cutaneous leishmaniasis, herpes zoster, and acquired perforating dermatosis [A32892]. Furthermore, since most topical cantharidin applications are most commonly available in a 0.7% formulation or a more potent 1% mixture, the 0.7% formulation is most commonly indicated for the treatment of common warts, periungual warts, and molluscum contagiosum while the more potent 1% mixture is typically limited only for use by healthcare professionals in a clinical setting for treating plantar warts and other more specialized off-label conditions [A32891, A32892, F32]. Moreover, there have also been studies into whether or not cantharidin could be effective at being used as an inflammatory model or in cancer treatment - either of which has yet to formally elucidate any results [A32892].
DB12332RucaparibIndicated as monotherapy for the treatment of patients with deleterious BRCA mutation (germline and/or somatic) associated advanced ovarian cancer who have been treated with two or more chemotherapies. Select patients for therapy based on an FDA-approved companion diagnostic for rucaparib.
DB12377RelebactamNot Available
DB12382R-306465Not Available
DB12445NitroaspirinNot Available
DB12447NadifloxacinNot Available
DB12449TempolNot Available
DB12459BelotecanNot Available
DB12531LobucavirNot Available
DB12539OltiprazNot Available
DB12545IndobufenNot Available
DB12565AbexinostatNot Available
DB12582PiperineNot Available
DB12598NafamostatUsed as an anticoagulant in patients with disseminative blood vessel coagulation, hemorrhagic lesions, and hemorrhagic tendencies. It prevents blood clot formation during extracorporeal circulation in patients undergoing continuous renal replacement therapy and extra corporeal membrane oxygenation.
DB12604SisomicinNot Available
DB12617MizoribineNot Available
DB12618ApocyninNot Available
DB12681SalirasibNot Available
DB12695Phenethyl IsothiocyanateNot Available
DB12716NB-001Not Available
DB12750N-omega-nitro-L-arginine methyl esterNot Available
DB12758AtreleutonNot Available
DB12769LometrexolNot Available
DB12783BenserazideThe primary therapeutic use for which benserazide is currently indicated for is as a combination therapy with levadopa for the treatment of Parkinson's disease in adults > 25 years of age, with the exception of drug-induced parkinsonism [F2, L2553]. At certain doses, the combination product of levodopa and benserazide may also be used to treat restless legs syndrome, which is sometimes associated with Parkinson's disease [L2553, T181]. There have also been some studies that have prompted the European Medicines Agency to confer orphan designation upon benserazide hydrochloride as a potential therapy for beta thalassaemia [F3]. Although studies are ongoing, no evidence has been formally elucidated as of yet [F3].
DB12831GabexateNo approved indication.
DB12863SivelestatNot Available
DB12870Buthionine SulfoximineNot Available
DB12912NolatrexedNot Available
DB12939Nikkomycin ZNot Available
DB12948DidoxNot Available
DB12967MitoguazoneNot Available
DB13014HypericinNot Available
DB13029MK-0873Not Available
DB13058Methanesulfonyl FluorideNot Available
DB13066LiarozoleNot Available
DB13083TalarozoleNot Available
DB13166ZofenoprilNot Available
DB13174RheinNo approved indication.
DB13182DaidzeinNot Available
DB13261SitafloxacinNot Available
DB13307ProscillaridinNot Available
DB13312DelaprilNot Available
DB13627Oxolinic acidNot Available
DB13694DistigmineNot Available
DB13767VorozoleNot Available
DB13772RufloxacinNot Available
DB13795BrodimoprimNot Available
DB13800Calcium levulinateThis new application of calcium is intended for use as a food fortifier, to fortify foods like sauces, condiments, beer, beverages, soft drinks, milk and milk products, soy milk and soy products with calcium nutrition [L2765]. Calcium levulinate can be used alone, or with calcium lactate, calcium chloride, and other compounds, either for pharmaceutical tablets, capsules, or injections preparation [L2765]. In essence, calcium levulinate is ultimately a relatively new calcium supplementation option [L2767].
DB13868AdefovirNot Available
DB13875HarmalineNot Available
DB13876BrofaromineNot Available
DB13877IniparibNot Available
DB13912Coumermycin A1Not Available
DB14025ClinafloxacinNot Available
DB14029FurafyllineNot Available
DB08044ABT-341Not Available
DB08059WortmanninNot Available
DB14058BasifunginNot Available
DB14059SC-236Not Available
DB14060NS-398Not Available
DB14062Concanamycin ANot Available
DB14125BenazeprilatNot Available
DB14126TenofovirNot Available
DB14207FosinoprilatNot Available
DB14208RamiprilatNot Available
DB14213PerindoprilatNot Available
DB14217QuinaprilatNot Available
DB14509Lithium carbonateLithium is used as a mood stabilizer, and is used for treatment of depression and mania. It is often used in bipolar disorder treatment.
DB14514Magnesium levulinateNot Available
DB07338AcifluorfenNot Available
DB07558acetylleucyl-leucyl-norleucinalNot Available
DB01990Cholesterol sulfateNot Available
DB020321-(3-Mercapto-2-Methyl-Propionyl)-Pyrrolidine-2-Carboxylic AcidNot Available
DB02132ZenarestatInvestigated for use/treatment in neuropathy (diabetic).
DB02234S-EthylisothioureaNot Available
DB02600Oseltamivir acidNot Available
DB02918ZardaverineNot Available
DB032852',4,4'-TrihydroxychalconeNot Available
DB03523BrequinarNot Available
DB03695PiritreximNot Available
DB04017ClorgilineNot Available
DB04377MeglutolNot Available
DB05383PimagedineInvestigated for use/treatment in diabetic kidney disease.
DB054827-ethyl-10-hydroxycamptothecinInvestigated for use/treatment in colorectal cancer.
DB07715EmodinNot Available
DB08162FasudilNot Available
DB08188EmivirineNot Available
DB11948LapachoneNot Available
DB12610EbselenNot Available
DB14726DabigatranNot Available
DrugDrug NameTargetType
DB00001LepirudinProthrombintarget
DB00006BivalirudinProthrombintarget
DB00006BivalirudinMyeloperoxidaseenzyme
DB00058Alpha-1-proteinase inhibitorNeutrophil elastasetarget
DB00091CiclosporinCalcium signal-modulating cyclophilin ligandtarget
DB00091CiclosporinPeptidyl-prolyl cis-trans isomerase Atarget
DB00091CiclosporinCalcineurin subunit B type 2target
DB00091CiclosporinCytochrome P450 3A5enzyme
DB00091CiclosporinCytochrome P450 3A4enzyme
DB00091CiclosporinCytochrome P450 3A7enzyme
DB00091CiclosporinMultidrug resistance protein 1transporter
DB00091CiclosporinCanalicular multispecific organic anion transporter 2transporter
DB00091CiclosporinBile salt export pumptransporter
DB00091CiclosporinMultidrug resistance-associated protein 1transporter
DB00091CiclosporinSolute carrier organic anion transporter family member 1A2transporter
DB00091CiclosporinIleal sodium/bile acid cotransportertransporter
DB00091CiclosporinSodium/bile acid cotransportertransporter
DB00091CiclosporinSolute carrier family 22 member 6transporter
DB00091CiclosporinMultidrug resistance-associated protein 7transporter
DB00091CiclosporinCanalicular multispecific organic anion transporter 1transporter
DB00091CiclosporinATP-binding cassette sub-family G member 2transporter
DB00091CiclosporinSolute carrier organic anion transporter family member 1B1transporter
DB00091CiclosporinCytochrome P450 2C19enzyme
DB00091CiclosporinCytochrome P450 2C8enzyme
DB00091CiclosporinCytochrome P450 2C9enzyme
DB00091CiclosporinCytochrome P450 2D6enzyme
DB00091CiclosporinPeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
DB00091CiclosporinSolute carrier organic anion transporter family member 1B3transporter
DB00175Pravastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB00175PravastatinSolute carrier organic anion transporter family member 2B1transporter
DB00175PravastatinMultidrug resistance protein 1transporter
DB00175PravastatinSolute carrier organic anion transporter family member 1A2transporter
DB00175PravastatinSolute carrier family 22 member 6transporter
DB00175PravastatinSolute carrier family 22 member 8transporter
DB00175PravastatinCanalicular multispecific organic anion transporter 1transporter
DB00175PravastatinSolute carrier family 22 member 11transporter
DB00175PravastatinATP-binding cassette sub-family G member 2transporter
DB00175PravastatinSolute carrier family 22 member 7transporter
DB00175PravastatinSolute carrier organic anion transporter family member 1B1transporter
DB00175PravastatinCytochrome P450 2C8enzyme
DB00175PravastatinMonocarboxylate transporter 1transporter
DB00175PravastatinBile salt export pumptransporter
DB00175PravastatinSolute carrier organic anion transporter family member 1B3transporter
DB00176FluvoxamineSodium-dependent serotonin transportertarget
DB00176FluvoxamineCytochrome P450 1A2enzyme
DB00176FluvoxamineCytochrome P450 2D6enzyme
DB00176FluvoxamineCytochrome P450 2C9enzyme
DB00176FluvoxamineCytochrome P450 2C19enzyme
DB00176FluvoxamineCytochrome P450 1A1enzyme
DB00176FluvoxamineCytochrome P450 3A4enzyme
DB00176FluvoxamineCytochrome P450 3A5enzyme
DB00176FluvoxamineCytochrome P450 3A7enzyme
DB00176FluvoxamineMultidrug resistance protein 1transporter
DB00176FluvoxamineCytochrome P450 2B6enzyme
DB00176FluvoxamineCytochrome P450 2E1enzyme
DB00176FluvoxaminePotassium voltage-gated channel subfamily H member 2target
DB00176FluvoxamineCytochrome P450 2C8enzyme
DB00176FluvoxamineBile salt export pumptransporter
DB00178RamiprilAngiotensin-converting enzymetarget
DB00178RamiprilSolute carrier family 15 member 1transporter
DB00178RamiprilSolute carrier family 15 member 2transporter
DB00178RamiprilCholinesteraseenzyme
DB00178RamiprilB1 bradykinin receptortarget
DB00179MasoprocolArachidonate 5-lipoxygenasetarget
DB00179MasoprocolCytochrome P450 2J2enzyme
DB00179MasoprocolSex hormone-binding globulintarget
DB00190CarbidopaAromatic-L-amino-acid decarboxylasetarget
DB00196FluconazoleCytochrome P450 3A4enzyme
DB00196FluconazoleCytochrome P450 2C9enzyme
DB00196FluconazoleCytochrome P450 2C19enzyme
DB00196FluconazoleCytochrome P450 3A5enzyme
DB00196FluconazoleCytochrome P450 3A7enzyme
DB00196FluconazoleMultidrug resistance protein 1transporter
DB00196FluconazoleLanosterol 14-alpha demethylasetarget
DB00196FluconazoleCytochrome P450 11B1, mitochondrialenzyme
DB00198OseltamivirNeuraminidasetarget
DB00198OseltamivirSialidase-1target
DB00198OseltamivirLiver carboxylesterase 1target
DB00198OseltamivirSialidase-2target
DB00198OseltamivirMultidrug resistance-associated protein 4transporter
DB00198OseltamivirSolute carrier family 15 member 1transporter
DB00198OseltamivirSolute carrier family 22 member 8transporter
DB00199Erythromycin23S rRNAtarget
DB00199ErythromycinCytochrome P450 3A4enzyme
DB00199ErythromycinCytochrome P450 3A7enzyme
DB00199ErythromycinMultidrug resistance protein 1transporter
DB00199ErythromycinSolute carrier organic anion transporter family member 1B1transporter
DB00199ErythromycinCytochrome P450 2B6enzyme
DB00199ErythromycinMotilin receptortarget
DB00199ErythromycinPotassium voltage-gated channel subfamily H member 2target
DB00199ErythromycinSerum albumintarget
DB00199ErythromycinCytochrome P450 3A5enzyme
DB00199ErythromycinSolute carrier organic anion transporter family member 1B3transporter
DB00199ErythromycinBile salt export pumptransporter
DB00199ErythromycinCytochrome P450 1A2enzyme
DB00201CaffeineAdenosine receptor A1target
DB00201CaffeinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB00201CaffeineAdenosine receptor A2atarget
DB00201CaffeineCytochrome P450 1A2enzyme
DB00201CaffeineRyanodine receptor 1target
DB00201CaffeineCytochrome P450 3A4enzyme
DB00201CaffeineCytochrome P450 3A5enzyme
DB00201CaffeineCytochrome P450 3A7enzyme
DB00201CaffeineMultidrug resistance protein 1transporter
DB00201CaffeineCytochrome P450 2E1enzyme
DB00201CaffeineCytochrome P450 2C8enzyme
DB00201CaffeineCytochrome P450 2C9enzyme
DB00201CaffeineCytochrome P450 1A1enzyme
DB00201CaffeineCytochrome P450 1B1enzyme
DB00201CaffeineCytochrome P450 2D6enzyme
DB00201CaffeineCyclic nucleotide phosphodiesterasetarget
DB00201CaffeineDNA-dependent protein kinase catalytic subunittarget
DB00201CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
DB00201CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
DB00201CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformtarget
DB00201CaffeineInositol 1,4,5-trisphosphate receptortarget
DB00201CaffeineSerine-protein kinase ATMtarget
DB00203SildenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00203SildenafilCytochrome P450 2C9enzyme
DB00203SildenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00203SildenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00203SildenafilCytochrome P450 3A4enzyme
DB00203SildenafilCytochrome P450 3A5enzyme
DB00203SildenafilCytochrome P450 3A7enzyme
DB00203SildenafilMultidrug resistance-associated protein 4transporter
DB00203SildenafilMultidrug resistance-associated protein 5transporter
DB00203SildenafilMultidrug resistance-associated protein 7transporter
DB00203SildenafilCytochrome P450 2C19enzyme
DB00203SildenafilCytochrome P450 2D6enzyme
DB00203SildenafilCytochrome P450 1A1enzyme
DB00203SildenafilCytochrome P450 2E1enzyme
DB00203SildenafilSolute carrier organic anion transporter family member 1B1transporter
DB00203SildenafilMultidrug resistance protein 1transporter
DB00205PyrimethamineBifunctional dihydrofolate reductase-thymidylate synthasetarget
DB00205PyrimethamineDihydrofolate reductasetarget
DB00205PyrimethamineCytochrome P450 2C8enzyme
DB00205PyrimethamineBeta-hexosaminidase subunit betatarget
DB00205PyrimethamineMultidrug and toxin extrusion protein 1transporter
DB00205PyrimethamineMultidrug and toxin extrusion protein 2transporter
DB00208TiclopidineP2Y purinoceptor 12target
DB00208TiclopidineCytochrome P450 3A4enzyme
DB00208TiclopidineCytochrome P450 2C19enzyme
DB00208TiclopidineCytochrome P450 2B6enzyme
DB00208TiclopidineCytochrome P450 2C9enzyme
DB00208TiclopidineCytochrome P450 2D6enzyme
DB00208TiclopidineMyeloperoxidaseenzyme
DB00208TiclopidineCytochrome P450 1A1enzyme
DB00208TiclopidineCytochrome P450 1A2enzyme
DB00208TiclopidineCytochrome P450 2C8enzyme
DB00208TiclopidineCytochrome P450 2E1enzyme
DB00212RemikirenRenintarget
DB00213PantoprazolePotassium-transporting ATPase alpha chain 1target
DB00213PantoprazoleCytochrome P450 2C19enzyme
DB00213PantoprazoleCytochrome P450 3A4enzyme
DB00213PantoprazoleMultidrug resistance protein 1transporter
DB00213PantoprazoleATP-binding cassette sub-family G member 2transporter
DB00213PantoprazoleSolute carrier organic anion transporter family member 1B1transporter
DB00218MoxifloxacinDNA gyrase subunit Atarget
DB00218MoxifloxacinDNA topoisomerase 4 subunit Atarget
DB00218MoxifloxacinDNA topoisomerase 2-alphatarget
DB00218MoxifloxacinCytochrome P450 1A2enzyme
DB00220NelfinavirHIV-1 proteasetarget
DB00220NelfinavirCytochrome P450 2C19enzyme
DB00220NelfinavirCytochrome P450 3A4enzyme
DB00220NelfinavirCytochrome P450 2B6enzyme
DB00220NelfinavirCytochrome P450 3A5enzyme
DB00220NelfinavirCytochrome P450 3A7enzyme
DB00220NelfinavirMultidrug resistance protein 1transporter
DB00220NelfinavirSolute carrier family 22 member 1transporter
DB00220NelfinavirSolute carrier organic anion transporter family member 1A2transporter
DB00220NelfinavirATP-binding cassette sub-family G member 2transporter
DB00220NelfinavirSolute carrier organic anion transporter family member 1B1transporter
DB00220NelfinavirCytochrome P450 2D6enzyme
DB00220NelfinavirSerum albumincarrier
DB00220NelfinavirUDP-glucuronosyltransferase 1-1enzyme
DB00220NelfinavirSolute carrier organic anion transporter family member 1B3transporter
DB00220NelfinavirSolute carrier organic anion transporter family member 2B1transporter
DB00220NelfinavirBile salt export pumptransporter
DB00220NelfinavirCytochrome P450 2C9enzyme
DB00224IndinavirHuman immunodeficiency virus type 1 proteasetarget
DB00224IndinavirCytochrome P450 3A4enzyme
DB00224IndinavirCytochrome P450 3A5enzyme
DB00224IndinavirCytochrome P450 3A7enzyme
DB00224IndinavirMultidrug resistance protein 1transporter
DB00224IndinavirSolute carrier family 22 member 1transporter
DB00224IndinavirMultidrug resistance-associated protein 1transporter
DB00224IndinavirSolute carrier organic anion transporter family member 1A2transporter
DB00224IndinavirSolute carrier organic anion transporter family member 1B1transporter
DB00224IndinavirCanalicular multispecific organic anion transporter 1transporter
DB00224IndinavirCytochrome P450 2D6enzyme
DB00224IndinavirUDP-glucuronosyltransferase 1-1enzyme
DB00224IndinavirSolute carrier organic anion transporter family member 2B1transporter
DB00224IndinavirBile salt export pumptransporter
DB00227Lovastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB00227LovastatinCytochrome P450 3A4enzyme
DB00227LovastatinCytochrome P450 2C8enzyme
DB00227LovastatinIntegrin alpha-Ltarget
DB00227LovastatinHistone deacetylase 2target
DB00227LovastatinSerum paraoxonase/lactonase 3enzyme
DB00227LovastatinCytochrome P450 2C9enzyme
DB00227LovastatinCytochrome P450 3A5enzyme
DB00227LovastatinCytochrome P450 3A7enzyme
DB00227LovastatinMultidrug resistance protein 1transporter
DB00227LovastatinSolute carrier organic anion transporter family member 1A2transporter
DB00227LovastatinSolute carrier organic anion transporter family member 1B1transporter
DB00227LovastatinCytochrome P450 2D6enzyme
DB00227LovastatinUDP-glucuronosyltransferase 1-1enzyme
DB00227LovastatinUDP-glucuronosyltransferase 1-3enzyme
DB00227LovastatinUDP-glucuronosyltransferase 2B7enzyme
DB00227LovastatinCanalicular multispecific organic anion transporter 1transporter
DB00227LovastatinBile salt export pumptransporter
DB00235MilrinonecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB00238NevirapineCytochrome P450 3A4enzyme
DB00238NevirapineCytochrome P450 2B6enzyme
DB00238NevirapineCytochrome P450 3A5enzyme
DB00238NevirapineCytochrome P450 2C9enzyme
DB00238NevirapineCytochrome P450 2A6enzyme
DB00238NevirapineCytochrome P450 2D6enzyme
DB00238NevirapineReverse transcriptase/RNaseHtarget
DB00238NevirapineSerum albumincarrier
DB00238NevirapineCytochrome P450 1A2enzyme
DB00238NevirapineSolute carrier family 22 member 1transporter
DB00249IdoxuridineThymidine kinasetarget
DB00249IdoxuridineDNAtarget
DB00250DapsoneInactive dihydropteroate synthase 2target
DB00250DapsoneDihydropteroate synthase 1target
DB00250DapsoneCytochrome P450 2C9enzyme
DB00250DapsoneCytochrome P450 2E1enzyme
DB00250DapsoneCytochrome P450 3A4enzyme
DB00250DapsoneDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00250DapsoneProstaglandin G/H synthase 1enzyme
DB00250DapsoneProstaglandin G/H synthase 2enzyme
DB00250DapsoneCytochrome P450 2C8enzyme
DB00250DapsoneCytochrome P450 2C19enzyme
DB00250DapsoneArylamine N-acetyltransferase 2enzyme
DB00250DapsoneCytochrome P450 3A5enzyme
DB00250DapsoneCytochrome P450 3A7enzyme
DB00250DapsoneMyeloperoxidaseenzyme
DB00250DapsoneCytochrome P450 2C18enzyme
DB00257ClotrimazoleIntermediate conductance calcium-activated potassium channel protein 4target
DB00257ClotrimazoleCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB00257ClotrimazoleCytochrome P450 2D6enzyme
DB00257ClotrimazoleCytochrome P450 2C8enzyme
DB00257ClotrimazoleCytochrome P450 3A4enzyme
DB00257ClotrimazoleCytochrome P450 2B6enzyme
DB00257ClotrimazoleCanalicular multispecific organic anion transporter 2transporter
DB00257ClotrimazoleMultidrug resistance protein 1transporter
DB00257ClotrimazoleCanalicular multispecific organic anion transporter 1transporter
DB00257ClotrimazoleCytochrome P450 11B1, mitochondrialenzyme
DB00257ClotrimazoleCytochrome P450 19A1enzyme
DB00257ClotrimazoleCytochrome P450 2A6enzyme
DB00257ClotrimazoleCytochrome P450 2C9enzyme
DB00257ClotrimazoleCytochrome P450 2E1enzyme
DB00257ClotrimazoleCytochrome P450 3A7enzyme
DB00257ClotrimazoleLanosterol 14-alpha demethylasetarget
DB00257ClotrimazoleNuclear receptor subfamily 1 group I member 2target
DB00257ClotrimazoleNuclear receptor subfamily 1 group I member 3target
DB00257ClotrimazoleBile salt export pumptransporter
DB00266DicoumarolVitamin K epoxide reductase complex subunit 1target
DB00266DicoumarolNAD(P)H dehydrogenase [quinone] 1target
DB00266DicoumarolQuinone oxidoreductasetarget
DB00266DicoumarolCytochrome P450 2C9enzyme
DB00266DicoumarolSerum albumincarrier
DB00266DicoumarolCytochrome P450 2C6enzyme
DB00266DicoumarolCytochrome P450 2C11enzyme
DB00277TheophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB00277TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB00277TheophyllineAdenosine receptor A2btarget
DB00277TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB00277TheophyllinecGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00277TheophyllineAdenosine receptor A1target
DB00277TheophyllineAdenosine receptor A2atarget
DB00277TheophyllineCytochrome P450 1A2enzyme
DB00277TheophyllineAdenosine deaminaseenzyme
DB00277TheophyllineCytochrome P450 2E1enzyme
DB00277TheophyllineCytochrome P450 3A4enzyme
DB00277TheophyllineSolute carrier family 22 member 7transporter
DB00277TheophyllineCytochrome P450 1A1enzyme
DB00277TheophyllineCytochrome P450 1B1enzyme
DB00277TheophyllineCytochrome P450 2C8enzyme
DB00277TheophyllineCytochrome P450 2D6enzyme
DB00277TheophyllineHistone deacetylase 2target
DB00277TheophyllineCopine-1target
DB00277TheophyllineMinor histocompatibility antigen H13target
DB00277TheophyllineNodal modulator 1target
DB00277TheophyllinePoly [ADP-ribose] polymerase 1target
DB00277TheophyllineProtein RIC-3target
DB00277TheophyllineTubulin monoglycylase TTLL3target
DB00278ArgatrobanProthrombintarget
DB00278ArgatrobanCytochrome P450 3A4enzyme
DB00278ArgatrobanCytochrome P450 3A5enzyme
DB00284AcarboseMaltase-glucoamylase, intestinaltarget
DB00284AcarboseLysosomal alpha-glucosidasetarget
DB00284AcarboseSucrase-isomaltase, intestinaltarget
DB00284AcarbosePancreatic alpha-amylasetarget
DB00293RaltitrexedThymidylate synthasetarget
DB00293RaltitrexedFolylpolyglutamate synthase, mitochondrialtarget
DB00300Tenofovir disoproxilReverse transcriptase/RNaseHtarget
DB00300Tenofovir disoproxilSolute carrier family 22 member 6transporter
DB00300Tenofovir disoproxilSolute carrier family 22 member 8transporter
DB00300Tenofovir disoproxilMultidrug resistance-associated protein 7transporter
DB00300Tenofovir disoproxilMultidrug resistance-associated protein 4transporter
DB00300Tenofovir disoproxilCanalicular multispecific organic anion transporter 1transporter
DB00300Tenofovir disoproxilAdenylate kinase 2, mitochondrialenzyme
DB00300Tenofovir disoproxilAdenylate kinase 4, mitochondrialenzyme
DB00300Tenofovir disoproxilNucleoside diphosphate kinase Aenzyme
DB00300Tenofovir disoproxilNucleoside diphosphate kinase Benzyme
DB00300Tenofovir disoproxilMultidrug resistance protein 1transporter
DB00305MitomycinDNAtarget
DB00305MitomycinNADPH--cytochrome P450 reductaseenzyme
DB00311EthoxzolamideCarbonic anhydrase 1target
DB00311EthoxzolamideSolute carrier family 22 member 6transporter
DB00311EthoxzolamideCarbonic anhydrase 2target
DB00311EthoxzolamideCarbonic anhydrase 4target
DB00311EthoxzolamideCarbonic anhydrase 7target
DB00311EthoxzolamideCarbonic anhydrase 3target
DB00313Valproic Acid4-aminobutyrate aminotransferase, mitochondrialtarget
DB00313Valproic AcidHistone deacetylase 9target
DB00313Valproic AcidShort/branched chain specific acyl-CoA dehydrogenase, mitochondrialtarget
DB00313Valproic AcidCytochrome P450 2A6enzyme
DB00313Valproic AcidCytochrome P450 2B6enzyme
DB00313Valproic AcidCytochrome P450 2C9enzyme
DB00313Valproic AcidSolute carrier family 22 member 5transporter
DB00313Valproic AcidSolute carrier family 22 member 6transporter
DB00313Valproic AcidSolute carrier family 22 member 8transporter
DB00313Valproic AcidMonocarboxylate transporter 1transporter
DB00313Valproic AcidSolute carrier family 22 member 7transporter
DB00313Valproic AcidCytochrome P450 3A5enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 1-9enzyme
DB00313Valproic AcidProstaglandin G/H synthase 1enzyme
DB00313Valproic AcidCytochrome P450 1A2enzyme
DB00313Valproic AcidCytochrome P450 2C18enzyme
DB00313Valproic AcidCytochrome P450 2C19enzyme
DB00313Valproic AcidCytochrome P450 2C8enzyme
DB00313Valproic AcidCytochrome P450 3A4enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 1-4enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 1-8enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 1-10enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 1-6enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 1-3enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 2B7enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 2B15enzyme
DB00313Valproic Acid2-oxoglutarate dehydrogenase, mitochondrialtarget
DB00313Valproic AcidSuccinate-semialdehyde dehydrogenase, mitochondrialtarget
DB00313Valproic AcidSodium channel proteintarget
DB00313Valproic AcidHistone deacetylase 2target
DB00313Valproic AcidPeroxisome proliferator-activated receptor alphatarget
DB00313Valproic AcidPeroxisome proliferator-activated receptor deltatarget
DB00313Valproic AcidPeroxisome proliferator-activated receptor gammatarget
DB00313Valproic AcidSerum albumincarrier
DB00313Valproic AcidUDP-glucuronosyltransferase 1-1enzyme
DB00313Valproic AcidSolute carrier organic anion transporter family member 2B1transporter
DB00314Capreomycin70S ribosometarget
DB00317GefitinibEpidermal growth factor receptortarget
DB00317GefitinibCytochrome P450 3A4enzyme
DB00317GefitinibCytochrome P450 2D6enzyme
DB00317GefitinibMultidrug resistance protein 1transporter
DB00317GefitinibATP-binding cassette sub-family G member 2transporter
DB00317GefitinibCytochrome P450 3A5enzyme
DB00317GefitinibCytochrome P450 1A1enzyme
DB00317GefitinibCytochrome P450 2C9enzyme
DB00317GefitinibCytochrome P450 2C19enzyme
DB00317GefitinibSerum albumincarrier
DB00317GefitinibAlpha-1-acid glycoprotein 1carrier
DB00323TolcaponeCatechol O-methyltransferasetarget
DB00323TolcaponeCytochrome P450 2C9enzyme
DB00328IndometacinProstaglandin G/H synthase 1target
DB00328IndometacinProstaglandin G/H synthase 2target
DB00328IndometacinCytochrome P450 2C19enzyme
DB00328IndometacinUDP-glucuronosyltransferase 1-9enzyme
DB00328IndometacinPhospholipase A2, membrane associatedtarget
DB00328IndometacinProstaglandin reductase 2target
DB00328IndometacinLactoylglutathione lyasetarget
DB00328IndometacinProstaglandin D2 receptor 2target
DB00328IndometacinPeroxisome proliferator-activated receptor gammatarget
DB00328IndometacinSerum albumincarrier
DB00328IndometacinCanalicular multispecific organic anion transporter 2transporter
DB00328IndometacinMultidrug resistance-associated protein 4transporter
DB00328IndometacinMultidrug resistance-associated protein 6transporter
DB00328IndometacinMultidrug resistance protein 1transporter
DB00328IndometacinMultidrug resistance-associated protein 1transporter
DB00328IndometacinSolute carrier organic anion transporter family member 1A2transporter
DB00328IndometacinSolute carrier family 22 member 6transporter
DB00328IndometacinSolute carrier family 22 member 8transporter
DB00328IndometacinCanalicular multispecific organic anion transporter 1transporter
DB00328IndometacinATP-binding cassette sub-family C member 11transporter
DB00328IndometacinSolute carrier family 22 member 11transporter
DB00328IndometacinSodium/bile acid cotransportertransporter
DB00328IndometacinSolute carrier family 22 member 7transporter
DB00328IndometacinCytochrome P450 2C9enzyme
DB00328IndometacinUDP-glucuronosyltransferase 1-1enzyme
DB00328IndometacinLiver carboxylesterase 1enzyme
DB00328IndometacinUDP-glucuronosyltransferase 2B7enzyme
DB00328IndometacinPeroxisome proliferator-activated receptor alphatarget
DB00328IndometacinAldo-keto reductase family 1 member C3target
DB00328IndometacinSolute carrier organic anion transporter family member 1B1transporter
DB00328IndometacinBile salt export pumptransporter
DB00337PimecrolimusPeptidyl-prolyl cis-trans isomerase FKBP1Atarget
DB00337PimecrolimusSerine/threonine-protein kinase mTORtarget
DB00337PimecrolimusCytochrome P450 3A4enzyme
DB00338OmeprazolePotassium-transporting ATPase alpha chain 1target
DB00338OmeprazoleCytochrome P450 2C19enzyme
DB00338OmeprazoleCytochrome P450 3A4enzyme
DB00338OmeprazoleCytochrome P450 2C9enzyme
DB00338OmeprazoleCytochrome P450 1A2enzyme
DB00338OmeprazoleCanalicular multispecific organic anion transporter 2transporter
DB00338OmeprazoleMultidrug resistance protein 1transporter
DB00338OmeprazoleATP-binding cassette sub-family G member 2transporter
DB00338OmeprazoleCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB00338OmeprazoleCytochrome P450 1A1enzyme
DB00338OmeprazoleCytochrome P450 1B1enzyme
DB00338OmeprazoleCytochrome P450 2C18enzyme
DB00338OmeprazoleCytochrome P450 2C8enzyme
DB00338OmeprazoleCytochrome P450 2D6enzyme
DB00338OmeprazoleAryl hydrocarbon receptortarget
DB00348Nitisinone4-hydroxyphenylpyruvate dioxygenasetarget
DB00357AminoglutethimideCytochrome P450 19A1target
DB00357AminoglutethimideCytochrome P450 2C19enzyme
DB00357AminoglutethimideCytochrome P450 3A4enzyme
DB00357AminoglutethimideCholesterol side-chain cleavage enzyme, mitochondrialtarget
DB00365GrepafloxacinDNA gyrase subunit Atarget
DB00365GrepafloxacinDNA topoisomerase 4 subunit Atarget
DB00365GrepafloxacinCytochrome P450 3A4enzyme
DB00365GrepafloxacinCytochrome P450 1A2enzyme
DB00365GrepafloxacinSolute carrier family 22 member 2transporter
DB00365GrepafloxacinSolute carrier family 22 member 5transporter
DB00365GrepafloxacinCanalicular multispecific organic anion transporter 1transporter
DB00365GrepafloxacinMultidrug resistance protein 1transporter
DB00365GrepafloxacinMultidrug resistance-associated protein 1transporter
DB00365GrepafloxacinSolute carrier family 22 member 6transporter
DB00380DexrazoxaneDNA topoisomerase 2-alphatarget
DB00380DexrazoxaneDNA topoisomerase 2-betatarget
DB00382TacrineAcetylcholinesterasetarget
DB00382TacrineCytochrome P450 1A2enzyme
DB00382TacrineCholinesterasetarget
DB00382TacrineMultidrug resistance protein 1transporter
DB00382TacrineLiver carboxylesterase 1target
DB00385ValrubicinDNA topoisomerase 2-alphatarget
DB00385ValrubicinDNAtarget
DB00390DigoxinSodium/potassium-transporting ATPase subunit alpha-1target
DB00390DigoxinCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB00390DigoxinMultidrug resistance protein 1transporter
DB00390DigoxinSolute carrier organic anion transporter family member 4C1transporter
DB00390DigoxinSolute carrier family 22 member 8transporter
DB00390DigoxinSolute carrier organic anion transporter family member 2B1transporter
DB00390DigoxinBile salt export pumptransporter
DB00390DigoxinSolute carrier organic anion transporter family member 1A2transporter
DB00390DigoxinOrganic solute transporter subunit alphatransporter
DB00390DigoxinOrganic solute transporter subunit betatransporter
DB00390DigoxinSolute carrier organic anion transporter family member 4A1transporter
DB00390DigoxinSolute carrier organic anion transporter family member 1B3transporter
DB00390DigoxinSolute carrier organic anion transporter family member 1C1transporter
DB00390DigoxinSolute carrier organic anion transporter family member 1B1transporter
DB00390DigoxinCytochrome P450 3A4enzyme
DB00398SorafenibSerine/threonine-protein kinase B-raftarget
DB00398SorafenibReceptor-type tyrosine-protein kinase FLT3target
DB00398SorafenibRAF proto-oncogene serine/threonine-protein kinasetarget
DB00398SorafenibVascular endothelial growth factor receptor 3target
DB00398SorafenibPlatelet-derived growth factor receptor betatarget
DB00398SorafenibMast/stem cell growth factor receptor Kittarget
DB00398SorafenibVascular endothelial growth factor receptor 2target
DB00398SorafenibCytochrome P450 3A4enzyme
DB00398SorafenibUDP-glucuronosyltransferase 1-9enzyme
DB00398SorafenibCytochrome P450 2B6enzyme
DB00398SorafenibCytochrome P450 2C8enzyme
DB00398SorafenibCytochrome P450 3A5enzyme
DB00398SorafenibCytochrome P450 3A7enzyme
DB00398SorafenibCytochrome P450 2C9enzyme
DB00398SorafenibMultidrug resistance-associated protein 4transporter
DB00398SorafenibMultidrug resistance protein 1transporter
DB00398SorafenibCanalicular multispecific organic anion transporter 1transporter
DB00398SorafenibATP-binding cassette sub-family G member 2transporter
DB00398SorafenibCytochrome P450 1A2enzyme
DB00398SorafenibCytochrome P450 2C19enzyme
DB00398SorafenibCytochrome P450 2D6enzyme
DB00398SorafenibUDP-glucuronosyltransferase 1-1enzyme
DB00398SorafenibRalA-binding protein 1transporter
DB00398SorafenibFibroblast growth factor receptor 1target
DB00398SorafenibProto-oncogene tyrosine-protein kinase receptor Rettarget
DB00398SorafenibVascular endothelial growth factor receptor 1target
DB00398SorafenibSolute carrier organic anion transporter family member 1B1transporter
DB00410MupirocinIsoleucine--tRNA ligasetarget
DB00419MiglustatCeramide glucosyltransferasetarget
DB00437AllopurinolXanthine dehydrogenase/oxidasetarget
DB00437AllopurinolSolute carrier family 22 member 8transporter
DB00437AllopurinolSolute carrier family 22 member 7transporter
DB00437AllopurinolAldehyde oxidaseenzyme
DB00437AllopurinolXanthine dehydrogenase/oxidaseenzyme
DB00439Cerivastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB00439CerivastatinCytochrome P450 2C8enzyme
DB00439CerivastatinCytochrome P450 3A4enzyme
DB00439CerivastatinCytochrome P450 2D6enzyme
DB00439CerivastatinCytochrome P450 2C9enzyme
DB00439CerivastatinCytochrome P450 3A5enzyme
DB00439CerivastatinCytochrome P450 3A7enzyme
DB00439CerivastatinMultidrug resistance protein 1transporter
DB00439CerivastatinCanalicular multispecific organic anion transporter 1transporter
DB00439CerivastatinATP-binding cassette sub-family G member 2transporter
DB00439CerivastatinSolute carrier organic anion transporter family member 1B1transporter
DB00439CerivastatinCytochrome P450 2B6enzyme
DB00439CerivastatinUDP-glucuronosyltransferase 1-1enzyme
DB00439CerivastatinBile salt export pumptransporter
DB00440TrimethoprimThymidylate synthasetarget
DB00440TrimethoprimDihydrofolate reductasetarget
DB00440TrimethoprimCytochrome P450 2C8enzyme
DB00440TrimethoprimCytochrome P450 3A4enzyme
DB00440TrimethoprimMultidrug resistance protein 1transporter
DB00440TrimethoprimCytochrome P450 2C9enzyme
DB00440TrimethoprimSolute carrier family 22 member 2transporter
DB00441GemcitabineRibonucleoside-diphosphate reductase large subunittarget
DB00441GemcitabineUMP-CMP kinasetarget
DB00441GemcitabineThymidylate synthasetarget
DB00441GemcitabineCytidine deaminaseenzyme
DB00441GemcitabineDeoxycytidine kinaseenzyme
DB00441GemcitabineMultidrug resistance protein 1transporter
DB00441GemcitabineMultidrug resistance-associated protein 7transporter
DB00441GemcitabineEquilibrative nucleoside transporter 1transporter
DB00441GemcitabineDNAtarget
DB00441GemcitabineSodium/nucleoside cotransporter 1transporter
DB00441GemcitabineEquilibrative nucleoside transporter 2transporter
DB00441GemcitabineSolute carrier family 28 member 3transporter
DB00444TeniposideDNA topoisomerase 2-alphatarget
DB00444TeniposideCytochrome P450 2C19enzyme
DB00444TeniposideCytochrome P450 2C9enzyme
DB00444TeniposideCytochrome P450 3A4enzyme
DB00444TeniposideMultidrug resistance-associated protein 6transporter
DB00444TeniposideATP-binding cassette sub-family G member 2transporter
DB00444TeniposideCytochrome P450 3A5enzyme
DB00445EpirubicinChromodomain-helicase-DNA-binding protein 1target
DB00445EpirubicinDNA topoisomerase 2-alphatarget
DB00445EpirubicinDNAtarget
DB00445EpirubicinMultidrug resistance-associated protein 1transporter
DB00445EpirubicinUDP-glucuronosyltransferase 2B7enzyme
DB00445EpirubicinCytosolic phospholipase A2enzyme
DB00446ChloramphenicolComplement decay-accelerating factortarget
DB00446ChloramphenicolDr hemagglutinin structural subunittarget
DB00446ChloramphenicolCytochrome P450 2C19enzyme
DB00446ChloramphenicolCytochrome P450 3A4enzyme
DB00446ChloramphenicolCytochrome P450 3A5enzyme
DB00446ChloramphenicolCytochrome P450 3A7enzyme
DB00446ChloramphenicolSolute carrier family 22 member 6transporter
DB00446Chloramphenicol50S ribosomal protein L16target
DB00446ChloramphenicolChloramphenicol acetyltransferase 3enzyme
DB00446ChloramphenicolChloramphenicol acetyltransferaseenzyme
DB00446ChloramphenicolChloramphenicol 3-O phosphotransferaseenzyme
DB00446ChloramphenicolCytochrome P450 2C8enzyme
DB00448LansoprazolePotassium-transporting ATPase alpha chain 1target
DB00448LansoprazoleCytochrome P450 2C19enzyme
DB00448LansoprazoleCytochrome P450 2C9enzyme
DB00448LansoprazoleCytochrome P450 3A4enzyme
DB00448LansoprazoleMultidrug resistance protein 1transporter
DB00448LansoprazoleATP-binding cassette sub-family G member 2transporter
DB00448LansoprazoleCytochrome P450 1A1enzyme
DB00448LansoprazoleCytochrome P450 1B1enzyme
DB00448LansoprazoleCytochrome P450 2C18enzyme
DB00448LansoprazoleCytochrome P450 2C8enzyme
DB00448LansoprazoleCytochrome P450 2D6enzyme
DB00448LansoprazoleMicrotubule-associated protein tautarget
DB00448LansoprazoleSolute carrier family 22 member 8transporter
DB00461NabumetoneProstaglandin G/H synthase 1target
DB00461NabumetoneProstaglandin G/H synthase 2target
DB00461NabumetoneMyeloperoxidaseenzyme
DB00461NabumetoneCytochrome P450 1A2enzyme
DB00465KetorolacProstaglandin G/H synthase 1target
DB00465KetorolacProstaglandin G/H synthase 2target
DB00467EnoxacinDNA gyrase subunit Atarget
DB00467EnoxacinDNA topoisomerase 4 subunit Atarget
DB00467EnoxacinDNA topoisomerase 2-alphatarget
DB00467EnoxacinCytochrome P450 1A2enzyme
DB00469TenoxicamProstaglandin G/H synthase 1target
DB00469TenoxicamProstaglandin G/H synthase 2target
DB00469TenoxicamCytochrome P450 2C9enzyme
DB00469TenoxicamSolute carrier family 22 member 8transporter
DB00472FluoxetineSodium-dependent serotonin transportertarget
DB00472FluoxetineCytochrome P450 2C9enzyme
DB00472FluoxetineCytochrome P450 2D6enzyme
DB00472FluoxetineCYP2B proteinenzyme
DB00472FluoxetineCytochrome P450 1A2enzyme
DB00472FluoxetineCytochrome P450 3A4enzyme
DB00472FluoxetineCytochrome P450 2C19enzyme
DB00472FluoxetineMultidrug resistance protein 1transporter
DB00472FluoxetineCytochrome P450 2B6enzyme
DB00472FluoxetineCytochrome P450 3A5enzyme
DB00472FluoxetineSerum albumincarrier
DB00472FluoxetineAlpha-1-acid glycoprotein 1carrier
DB00472FluoxetinePotassium voltage-gated channel subfamily H member 2target
DB00472Fluoxetine5-hydroxytryptamine receptor 2Ctarget
DB00472FluoxetineCyclin-dependent kinases regulatory subunit 1target
DB00472FluoxetineNeuronal acetylcholine receptor subunit alpha-2target
DB00472FluoxetineNeuronal acetylcholine receptor subunit alpha-3target
DB00472FluoxetineNeuronal acetylcholine receptor subunit beta-4target
DB00478RimantadineMatrix protein 2target
DB00482CelecoxibProstaglandin G/H synthase 2target
DB00482Celecoxib3-phosphoinositide-dependent protein kinase 1target
DB00482CelecoxibCytochrome P450 2C9enzyme
DB00482CelecoxibCytochrome P450 2D6enzyme
DB00482CelecoxibMultidrug resistance-associated protein 4transporter
DB00482CelecoxibCytochrome P450 3A4enzyme
DB00482CelecoxibCytochrome P450 2C8enzyme
DB00482CelecoxibCarbonic anhydrase 2target
DB00482CelecoxibCarbonic anhydrase 3target
DB00482CelecoxibATP-binding cassette sub-family B member 5target
DB00482CelecoxibATP-binding cassette sub-family G member 2target
DB00482CelecoxibMultidrug resistance protein 1target
DB00482CelecoxibBile salt export pumptransporter
DB00487PefloxacinDNA gyrase subunit Atarget
DB00487PefloxacinDNA topoisomerase 4 subunit Atarget
DB00487PefloxacinDNA topoisomerase 2-alphatarget
DB00487PefloxacinCytochrome P450 1A2enzyme
DB00487PefloxacinDNA topoisomerase 1target
DB00491MiglitolMaltase-glucoamylase, intestinaltarget
DB00491MiglitolPancreatic alpha-amylaseenzyme
DB00491MiglitolLysosomal alpha-glucosidasetarget
DB00491MiglitolNeutral alpha-glucosidase ABtarget
DB00491MiglitolNeutral alpha-glucosidase Ctarget
DB00492FosinoprilAngiotensin-converting enzymetarget
DB00492FosinoprilSolute carrier family 15 member 1transporter
DB00492FosinoprilSolute carrier family 15 member 2transporter
DB00494EntacaponeCatechol O-methyltransferasetarget
DB00494EntacaponeCatechol O-methyltransferaseenzyme
DB00494EntacaponeUDP-glucuronosyltransferase 1-9enzyme
DB00494EntacaponeCytochrome P450 2D6enzyme
DB00495ZidovudineSerum albumincarrier
DB00495ZidovudineCytochrome P450 2A6enzyme
DB00495ZidovudineCytochrome P450 2C8enzyme
DB00495ZidovudineCytochrome P450 2C9enzyme
DB00495ZidovudineCytochrome P450 3A4enzyme
DB00495ZidovudineReverse transcriptase/RNaseHtarget
DB00495ZidovudineSolute carrier family 22 member 2transporter
DB00495ZidovudineSolute carrier family 22 member 6transporter
DB00495ZidovudineSolute carrier family 22 member 7transporter
DB00495ZidovudineSolute carrier family 22 member 8transporter
DB00495ZidovudineSolute carrier family 22 member 11transporter
DB00495ZidovudineSodium/nucleoside cotransporter 1transporter
DB00495ZidovudineEquilibrative nucleoside transporter 2transporter
DB00495ZidovudineMultidrug resistance protein 1transporter
DB00495ZidovudineMultidrug resistance-associated protein 4transporter
DB00495ZidovudineMultidrug resistance-associated protein 5transporter
DB00495ZidovudineATP-binding cassette sub-family G member 2transporter
DB00495ZidovudineTelomerase reverse transcriptasetarget
DB00495ZidovudineThymidine kinase, cytosolicenzyme
DB00495ZidovudineUDP-glucuronosyltransferase 2B7enzyme
DB00495ZidovudineUDP-glucuronosyltransferase 1-1enzyme
DB00500TolmetinProstaglandin G/H synthase 1target
DB00500TolmetinProstaglandin G/H synthase 2target
DB00500TolmetinSolute carrier family 22 member 6transporter
DB00500TolmetinTryptophan 2,3-dioxygenaseenzyme
DB00500TolmetinMyeloperoxidaseenzyme
DB00500TolmetinSerum albumincarrier
DB00501CimetidineHistamine H2 receptortarget
DB00501CimetidineCytochrome P450 1A2enzyme
DB00501CimetidineCytochrome P450 2D6enzyme
DB00501CimetidineCytochrome P450 2C19enzyme
DB00501CimetidineCytochrome P450 3A4enzyme
DB00501CimetidineCytochrome P450 3A5enzyme
DB00501CimetidineCytochrome P450 3A7enzyme
DB00501CimetidineMultidrug resistance protein 1transporter
DB00501CimetidineSolute carrier family 22 member 2transporter
DB00501CimetidineSolute carrier family 22 member 1transporter
DB00501CimetidineSolute carrier family 22 member 3transporter
DB00501CimetidineSolute carrier family 22 member 5transporter
DB00501CimetidineSolute carrier family 22 member 6transporter
DB00501CimetidineSolute carrier family 22 member 8transporter
DB00501CimetidineMultidrug and toxin extrusion protein 1transporter
DB00501CimetidineSolute carrier family 22 member 4transporter
DB00501CimetidineSolute carrier family 22 member 11transporter
DB00501CimetidineSolute carrier family 22 member 7transporter
DB00501CimetidineCytochrome P450 11B1, mitochondrialenzyme
DB00501CimetidineCytochrome P450 2C8enzyme
DB00501CimetidineCytochrome P450 2C9enzyme
DB00501CimetidineCytochrome P450 2E1enzyme
DB00501CimetidineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00501CimetidineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00501CimetidineBile salt export pumptransporter
DB00501CimetidineMultidrug and toxin extrusion protein 2transporter
DB00503RitonavirHuman immunodeficiency virus type 1 proteasetarget
DB00503RitonavirCytochrome P450 2D6enzyme
DB00503RitonavirCytochrome P450 2C9enzyme
DB00503RitonavirCytochrome P450 2C19enzyme
DB00503RitonavirCytochrome P450 2B6enzyme
DB00503RitonavirCytochrome P450 2C8enzyme
DB00503RitonavirMultidrug resistance protein 1transporter
DB00503RitonavirMultidrug resistance-associated protein 1transporter
DB00503RitonavirCanalicular multispecific organic anion transporter 1transporter
DB00503RitonavirSolute carrier organic anion transporter family member 1A2transporter
DB00503RitonavirATP-binding cassette sub-family G member 2transporter
DB00503RitonavirSolute carrier organic anion transporter family member 1B1transporter
DB00503RitonavirCytochrome P450 1A2enzyme
DB00503RitonavirCytochrome P450 2E1enzyme
DB00503RitonavirNuclear receptor subfamily 1 group I member 2target
DB00503RitonavirSerum albumincarrier
DB00503RitonavirCytochrome P450 3A4enzyme
DB00503RitonavirCytochrome P450 3A5enzyme
DB00503RitonavirCytochrome P450 3A7enzyme
DB00503RitonavirCytochrome P450 3A43enzyme
DB00503RitonavirUDP-glucuronosyltransferase 1-1enzyme
DB00503RitonavirSolute carrier organic anion transporter family member 2B1transporter
DB00503RitonavirBile salt export pumptransporter
DB00511AcetyldigitoxinSodium/potassium-transporting ATPase subunit alpha-1target
DB00519TrandolaprilAngiotensin-converting enzymetarget
DB00519TrandolaprilSolute carrier family 15 member 1transporter
DB00519TrandolaprilSolute carrier family 15 member 2transporter
DB00519TrandolaprilLiver carboxylesterase 1enzyme
DB00529FoscarnetDNA polymerase catalytic subunittarget
DB00529FoscarnetDNA polymerase catalytic subunittarget
DB00529FoscarnetSolute carrier family 22 member 6transporter
DB00529FoscarnetMonocarboxylate transporter 1transporter
DB00530ErlotinibEpidermal growth factor receptortarget
DB00530ErlotinibCytochrome P450 3A4enzyme
DB00530ErlotinibATP-binding cassette sub-family G member 2transporter
DB00530ErlotinibMultidrug resistance protein 1transporter
DB00530ErlotinibNuclear receptor subfamily 1 group I member 2target
DB00530ErlotinibCytochrome P450 3A5enzyme
DB00530ErlotinibCytochrome P450 1A1enzyme
DB00530ErlotinibCytochrome P450 1A2enzyme
DB00530ErlotinibCytochrome P450 1B1enzyme
DB00530ErlotinibCytochrome P450 2D6enzyme
DB00530ErlotinibCytochrome P450 2C8enzyme
DB00530ErlotinibUDP-glucuronosyltransferase 1-1enzyme
DB00530ErlotinibSerum albumincarrier
DB00530ErlotinibAlpha-1-acid glycoprotein 1carrier
DB00530ErlotinibSolute carrier organic anion transporter family member 2B1transporter
DB00533RofecoxibProstaglandin G/H synthase 2target
DB00533RofecoxibElastintarget
DB00533RofecoxibCytochrome P450 3A4enzyme
DB00533RofecoxibCytochrome P450 1A2enzyme
DB00533RofecoxibMultidrug resistance-associated protein 4transporter
DB00533RofecoxibProstaglandin G/H synthase 1enzyme
DB00533RofecoxibCytochrome P450 2C8enzyme
DB00533RofecoxibCytochrome P450 2C9enzyme
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 2-alphatarget
DB00537CiprofloxacinCytochrome P450 1A2enzyme
DB00537CiprofloxacinCytochrome P450 3A4enzyme
DB00537CiprofloxacinCytochrome P450 3A5enzyme
DB00537CiprofloxacinCytochrome P450 3A7enzyme
DB00537CiprofloxacinMultidrug resistance protein 1transporter
DB00537CiprofloxacinPotassium voltage-gated channel subfamily H member 2target
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Btarget
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinMultidrug resistance protein MdtKtarget
DB00537CiprofloxacinGyrase Atarget
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinMultidrug and toxin extrusion protein 1transporter
DB00537CiprofloxacinMultidrug and toxin extrusion protein 2transporter
DB00542BenazeprilAngiotensin-converting enzymetarget
DB00542BenazeprilMethylenetetrahydrofolate reductaseenzyme
DB00542BenazeprilSolute carrier family 15 member 1transporter
DB00542BenazeprilSolute carrier family 15 member 2transporter
DB00545PyridostigmineAcetylcholinesterasetarget
DB00545PyridostigmineCytochrome P450 3A4enzyme
DB00545PyridostigmineCholinesterasetarget
DB00545PyridostigmineSerum albumintarget
DB00551Acetohydroxamic acidUrease subunit alphatarget
DB00551Acetohydroxamic acidMacrophage metalloelastasetarget
DB00552PentostatinAdenosine deaminasetarget
DB00554PiroxicamProstaglandin G/H synthase 1target
DB00554PiroxicamProstaglandin G/H synthase 2target
DB00554PiroxicamSerum albumincarrier
DB00554PiroxicamCytochrome P450 2C9enzyme
DB00554PiroxicamSolute carrier family 22 member 6transporter
DB00554PiroxicamSolute carrier family 22 member 8transporter
DB00554PiroxicamSolute carrier family 22 member 11transporter
DB00554PiroxicamCytochrome P450 2C8enzyme
DB00554PiroxicamSolute carrier organic anion transporter family member 2B1transporter
DB00558ZanamivirNeuraminidasetarget
DB00558ZanamivirNeuraminidasetarget
DB00558ZanamivirSialidase-2target
DB00563MethotrexateDihydrofolate reductasetarget
DB00563MethotrexateAldehyde oxidaseenzyme
DB00563MethotrexateMethylenetetrahydrofolate reductaseenzyme
DB00563MethotrexateSerum albumincarrier
DB00563MethotrexateCanalicular multispecific organic anion transporter 2transporter
DB00563MethotrexateMultidrug resistance-associated protein 4transporter
DB00563MethotrexateMultidrug resistance-associated protein 1transporter
DB00563MethotrexateSolute carrier family 22 member 6transporter
DB00563MethotrexateMultidrug resistance-associated protein 7transporter
DB00563MethotrexateSolute carrier family 22 member 8transporter
DB00563MethotrexateCanalicular multispecific organic anion transporter 1transporter
DB00563MethotrexateMultidrug resistance protein 1transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1A2transporter
DB00563MethotrexateMonocarboxylate transporter 1transporter
DB00563MethotrexateATP-binding cassette sub-family C member 11transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1B3transporter
DB00563MethotrexateSolute carrier family 22 member 11transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1C1transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 3A1transporter
DB00563MethotrexateATP-binding cassette sub-family G member 2transporter
DB00563MethotrexateSolute carrier family 22 member 7transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1B1transporter
DB00563Methotrexate6-phosphogluconate dehydrogenase, decarboxylatingenzyme
DB00563MethotrexateProton-coupled folate transportertransporter
DB00563MethotrexateFolylpolyglutamate synthase, mitochondrialenzyme
DB00563MethotrexateGamma-glutamyl hydrolaseenzyme
DB00563MethotrexateDihydrofolate reductaseenzyme
DB00563MethotrexateThymidylate synthaseenzyme
DB00563MethotrexateBifunctional purine biosynthesis protein PURHenzyme
DB00563MethotrexateSolute carrier organic anion transporter family member 4C1transporter
DB00563MethotrexateFolate transporter 1transporter
DB00563MethotrexateFolate receptor alphatransporter
DB00563MethotrexateCytochrome P450 3A4enzyme
DB00573FenoprofenProstaglandin G/H synthase 1target
DB00573FenoprofenProstaglandin G/H synthase 2target
DB00573FenoprofenSerum albumincarrier
DB00573FenoprofenPeroxisome proliferator-activated receptor alphatarget
DB00573FenoprofenPeroxisome proliferator-activated receptor gammatarget
DB00580ValdecoxibProstaglandin G/H synthase 2target
DB00580ValdecoxibCytochrome P450 2C9enzyme
DB00580ValdecoxibCytochrome P450 3A4enzyme
DB00580ValdecoxibUDP-glucuronosyltransferase 1-9enzyme
DB00580ValdecoxibCarbonic anhydrase 2target
DB00580ValdecoxibCarbonic anhydrase 3target
DB00582VoriconazoleCytochrome P450 2C19enzyme
DB00582VoriconazoleCytochrome P450 3A4enzyme
DB00582VoriconazoleCytochrome P450 2C9enzyme
DB00582VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00582VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00582VoriconazoleCytochrome P450 3A5enzyme
DB00582VoriconazoleCytochrome P450 3A7enzyme
DB00582VoriconazoleProstaglandin G/H synthase 1enzyme
DB00582VoriconazoleLanosterol 14-alpha demethylasetarget
DB00582VoriconazoleCytochrome P450 2B6enzyme
DB00584EnalaprilAngiotensin-converting enzymetarget
DB00584EnalaprilCytochrome P450 3A4enzyme
DB00584EnalaprilMultidrug resistance protein 1transporter
DB00584EnalaprilSolute carrier family 15 member 1transporter
DB00584EnalaprilSolute carrier family 22 member 6transporter
DB00584EnalaprilSolute carrier family 22 member 8transporter
DB00584EnalaprilSolute carrier family 22 member 7transporter
DB00584EnalaprilSolute carrier organic anion transporter family member 1A2transporter
DB00586DiclofenacProstaglandin G/H synthase 1target
DB00586DiclofenacProstaglandin G/H synthase 2target
DB00586DiclofenacTransthyretincarrier
DB00586DiclofenacCytochrome P450 2C9enzyme
DB00586DiclofenacCytochrome P450 2C19enzyme
DB00586DiclofenacCytochrome P450 1A2enzyme
DB00586DiclofenacCytochrome P450 2C8enzyme
DB00586DiclofenacUDP-glucuronosyltransferase 1-1enzyme
DB00586DiclofenacSerum albumincarrier
DB00586DiclofenacMultidrug resistance-associated protein 4transporter
DB00586DiclofenacMultidrug resistance protein 1transporter
DB00586DiclofenacMultidrug resistance-associated protein 1transporter
DB00586DiclofenacSolute carrier family 22 member 6transporter
DB00586DiclofenacSolute carrier family 22 member 8transporter
DB00586DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DB00586DiclofenacSolute carrier family 22 member 11transporter
DB00586DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DB00586DiclofenacProstaglandin G/H synthase 1enzyme
DB00586DiclofenacCytochrome P450 3A4enzyme
DB00586DiclofenacCytochrome P450 1A1enzyme
DB00586DiclofenacCytochrome P450 2B6enzyme
DB00586DiclofenacCytochrome P450 2C18enzyme
DB00586DiclofenacCytochrome P450 2E1enzyme
DB00586DiclofenacArachidonate 5-lipoxygenasetarget
DB00586DiclofenacSodium channel protein type 4 subunit alphatarget
DB00586DiclofenacAcid-sensing ion channel 1target
DB00586DiclofenacPotassium voltage-gated channel subfamily KQT member 2target
DB00586DiclofenacPotassium voltage-gated channel subfamily KQT member 3target
DB00586DiclofenacPhospholipase A2, membrane associatedtarget
DB00586DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DB00586DiclofenacBile salt export pumptransporter
DB00601Linezolid23S rRNAtarget
DB00601LinezolidAmine oxidase [flavin-containing] Aenzyme
DB00601LinezolidAmine oxidase [flavin-containing] Benzyme
DB00605SulindacProstaglandin G/H synthase 2target
DB00605SulindacAldose reductasetarget
DB00605SulindacProstaglandin G/H synthase 1target
DB00605SulindacMitogen-activated protein kinase 3target
DB00605SulindacPeroxisome proliferator-activated receptor deltatarget
DB00605SulindacProstaglandin D2 receptor 2target
DB00605SulindacSerum albumincarrier
DB00605SulindacSolute carrier family 22 member 6transporter
DB00605SulindacCytochrome P450 1A1enzyme
DB00605SulindacAldo-keto reductase family 1 member B10target
DB00614FurazolidoneDNAtarget
DB00614FurazolidoneAmine oxidase [flavin-containing] Benzyme
DB00614FurazolidoneAmine oxidase [flavin-containing] Aenzyme
DB00616CandoxatrilNeprilysintarget
DB00616CandoxatrilAngiotensin-converting enzymetarget
DB00619ImatinibPlatelet-derived growth factor receptor betatarget
DB00619ImatinibTyrosine-protein kinase ABL1target
DB00619ImatinibMast/stem cell growth factor receptor Kittarget
DB00619ImatinibRET proto-oncogenetarget
DB00619ImatinibHigh affinity nerve growth factor receptortarget
DB00619ImatinibMacrophage colony-stimulating factor 1 receptortarget
DB00619ImatinibPlatelet-derived growth factor receptor alphatarget
DB00619ImatinibEpithelial discoidin domain-containing receptor 1target
DB00619ImatinibCytochrome P450 3A4enzyme
DB00619ImatinibBCR/ABL fusion protein isoform X9target
DB00619ImatinibCytochrome P450 1A2enzyme
DB00619ImatinibCytochrome P450 2D6enzyme
DB00619ImatinibCytochrome P450 2C9enzyme
DB00619ImatinibCytochrome P450 2C19enzyme
DB00619ImatinibCytochrome P450 3A5enzyme
DB00619ImatinibCytochrome P450 3A7enzyme
DB00619ImatinibSolute carrier family 22 member 1transporter
DB00619ImatinibMultidrug resistance protein 1transporter
DB00619ImatinibSolute carrier family 22 member 2transporter
DB00619ImatinibATP-binding cassette sub-family G member 2transporter
DB00619ImatinibATP-binding cassette sub-family A member 3transporter
DB00619ImatinibProstaglandin G/H synthase 1enzyme
DB00619ImatinibSerum albumincarrier
DB00619ImatinibAlpha-1-acid glycoprotein 1carrier
DB00619ImatinibBile salt export pumptransporter
DB00619ImatinibCytochrome P450 2C8enzyme
DB00620TriamcinoloneCorticosteroid-binding globulincarrier
DB00620TriamcinoloneGlucocorticoid receptortarget
DB00620TriamcinoloneCytochrome P450 3A4enzyme
DB00620TriamcinoloneProstaglandin G/H synthase 2enzyme
DB00620TriamcinoloneCholinesteraseenzyme
DB00625EfavirenzCytochrome P450 2B6enzyme
DB00625EfavirenzCytochrome P450 3A4enzyme
DB00625EfavirenzCytochrome P450 2C19enzyme
DB00625EfavirenzCytochrome P450 2C9enzyme
DB00625EfavirenzCytochrome P450 1A2enzyme
DB00625EfavirenzCytochrome P450 2D6enzyme
DB00625EfavirenzReverse transcriptase/RNaseHtarget
DB00625EfavirenzCytochrome P450 2C8enzyme
DB00625EfavirenzSerum albumincarrier
DB00625EfavirenzCytochrome P450 3A5enzyme
DB00625EfavirenzCytochrome P450 3A7enzyme
DB00625EfavirenzUDP-glucuronosyltransferase 1-1enzyme
DB00625EfavirenzBile salt export pumptransporter
DB00625EfavirenzSolute carrier family 22 member 1transporter
DB00641Simvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB00641SimvastatinIntegrin beta-2target
DB00641SimvastatinCytochrome P450 3A4enzyme
DB00641SimvastatinCytochrome P450 2C8enzyme
DB00641SimvastatinCytochrome P450 2C9enzyme
DB00641SimvastatinCytochrome P450 2C19enzyme
DB00641SimvastatinCytochrome P450 3A5enzyme
DB00641SimvastatinCytochrome P450 3A7enzyme
DB00641SimvastatinMultidrug resistance protein 1transporter
DB00641SimvastatinSolute carrier organic anion transporter family member 1A2transporter
DB00641SimvastatinSolute carrier organic anion transporter family member 1B1transporter
DB00641SimvastatinCytochrome P450 2B6enzyme
DB00641SimvastatinCytochrome P450 2D6enzyme
DB00641SimvastatinUDP-glucuronosyltransferase 1-1enzyme
DB00641SimvastatinUDP-glucuronosyltransferase 1-3enzyme
DB00641SimvastatinUDP-glucuronosyltransferase 2B7enzyme
DB00641SimvastatinCanalicular multispecific organic anion transporter 1transporter
DB00641SimvastatinIntegrin alpha-Ltarget
DB00641SimvastatinBile salt export pumptransporter
DB00642PemetrexedThymidylate synthasetarget
DB00642PemetrexedDihydrofolate reductasetarget
DB00642PemetrexedTrifunctional purine biosynthetic protein adenosine-3target
DB00642PemetrexedDeoxycytidine kinaseenzyme
DB00642PemetrexedBifunctional purine biosynthesis protein PURHtarget
DB00642PemetrexedEquilibrative nucleoside transporter 1enzyme
DB00642PemetrexedSolute carrier family 22 member 8transporter
DB00649StavudineSolute carrier family 22 member 6transporter
DB00649StavudineReverse transcriptase/RNaseHtarget
DB00649StavudineSodium/nucleoside cotransporter 1transporter
DB00649StavudineSerum albumincarrier
DB00651DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB00651DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB00651DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
DB00651DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB00651DyphyllineHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7Atarget
DB00651DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 7Btarget
DB00651DyphyllineAdenosine receptor A1target
DB00651DyphyllineAdenosine receptor A2atarget
DB00674GalantamineAcetylcholinesterasetarget
DB00674GalantamineCytochrome P450 3A4enzyme
DB00674GalantamineCytochrome P450 2D6enzyme
DB00674GalantamineAcetylcholine receptor subunit alphatarget
DB00674GalantamineAcetylcholine receptor subunit betatarget
DB00674GalantamineAcetylcholine receptor subunit deltatarget
DB00674GalantamineAcetylcholine receptor subunit gammatarget
DB00674GalantamineAcetylcholine receptor subunit epsilontarget
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-2target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-3target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-4target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-5target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-6target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-7target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-9target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-10target
DB00674GalantamineNeuronal acetylcholine receptor subunit beta-2target
DB00674GalantamineNeuronal acetylcholine receptor subunit beta-3target
DB00674GalantamineNeuronal acetylcholine receptor subunit beta-4target
DB00674GalantamineCholinesterasetarget
DB00677IsoflurophateCholinesterasetarget
DB00677IsoflurophateAcetylcholinesterasetarget
DB00677IsoflurophateCholinesteraseenzyme
DB00677IsoflurophateSerum albumincarrier
DB00677IsoflurophateSerotransferrintarget
DB00685TrovafloxacinDNA gyrase subunit Atarget
DB00685TrovafloxacinDNA topoisomerase 4 subunit Atarget
DB00685TrovafloxacinDNA topoisomerase 2-alphatarget
DB00685TrovafloxacinCytochrome P450 1A2enzyme
DB00688Mycophenolate mofetilInosine-5'-monophosphate dehydrogenase 2target
DB00688Mycophenolate mofetilInosine-5'-monophosphate dehydrogenase 1target
DB00688Mycophenolate mofetilUDP-glucuronosyltransferase 1-1enzyme
DB00688Mycophenolate mofetilUDP-glucuronosyltransferase 1-7enzyme
DB00688Mycophenolate mofetilUDP-glucuronosyltransferase 1-6enzyme
DB00688Mycophenolate mofetilUDP-glucuronosyltransferase 1-9enzyme
DB00688Mycophenolate mofetilUDP-glucuronosyltransferase 2B7enzyme
DB00688Mycophenolate mofetilUDP-glucuronosyltransferase 1-8enzyme
DB00688Mycophenolate mofetilUDP-glucuronosyltransferase 1-10enzyme
DB00688Mycophenolate mofetilLiver carboxylesterase 1enzyme
DB00688Mycophenolate mofetilCocaine esteraseenzyme
DB00688Mycophenolate mofetilSerum albumincarrier
DB00688Mycophenolate mofetilCytochrome P450 3A4enzyme
DB00688Mycophenolate mofetilCytochrome P450 3A5enzyme
DB00688Mycophenolate mofetilCytochrome P450 2C8enzyme
DB00688Mycophenolate mofetilSolute carrier organic anion transporter family member 1B1transporter
DB00688Mycophenolate mofetilSolute carrier organic anion transporter family member 1B3transporter
DB00688Mycophenolate mofetilCanalicular multispecific organic anion transporter 1transporter
DB00688Mycophenolate mofetilATP-binding cassette sub-family G member 2transporter
DB00688Mycophenolate mofetilMultidrug resistance protein 1transporter
DB00691MoexiprilAngiotensin-converting enzymetarget
DB00691MoexiprilSolute carrier family 15 member 1transporter
DB00691MoexiprilSolute carrier family 15 member 2transporter
DB00691MoexiprilAngiotensin-converting enzyme 2target
DB00694DaunorubicinDNAtarget
DB00694DaunorubicinXanthine dehydrogenase/oxidaseenzyme
DB00694DaunorubicinCytochrome P450 3A5enzyme
DB00694DaunorubicinNADPH--cytochrome P450 reductaseenzyme
DB00694DaunorubicinMultidrug resistance protein 1transporter
DB00694DaunorubicinMultidrug resistance-associated protein 1transporter
DB00694DaunorubicinCanalicular multispecific organic anion transporter 1transporter
DB00694DaunorubicinMultidrug resistance-associated protein 6transporter
DB00694DaunorubicinBile salt export pumptransporter
DB00694DaunorubicinMultidrug resistance-associated protein 7transporter
DB00694DaunorubicinATP-binding cassette sub-family G member 2transporter
DB00694DaunorubicinDNA topoisomerase 2-alphatarget
DB00694DaunorubicinDNA topoisomerase 2-betatarget
DB00694DaunorubicinCytochrome P450 1A1enzyme
DB00694DaunorubicinCytochrome P450 1B1enzyme
DB00694DaunorubicinCytochrome P450 3A4enzyme
DB00701AmprenavirHuman immunodeficiency virus type 1 proteasetarget
DB00701AmprenavirCytochrome P450 3A4enzyme
DB00701AmprenavirMultidrug resistance protein 1transporter
DB00701AmprenavirMultidrug resistance-associated protein 1transporter
DB00701AmprenavirCytochrome P450 2B6enzyme
DB00701AmprenavirCytochrome P450 2C19enzyme
DB00701AmprenavirCytochrome P450 2C8enzyme
DB00701AmprenavirCytochrome P450 2C9enzyme
DB00701AmprenavirCytochrome P450 2D6enzyme
DB00701AmprenavirCytochrome P450 3A5enzyme
DB00701AmprenavirSolute carrier organic anion transporter family member 1B1transporter
DB00703MethazolamideCarbonic anhydrase 1target
DB00703MethazolamideSolute carrier family 22 member 6transporter
DB00703MethazolamideCytochrome P450 2C19enzyme
DB00703MethazolamideCytochrome P450 2D6enzyme
DB00703MethazolamideCytochrome P450 2E1enzyme
DB00703MethazolamideCytochrome P450 3A4enzyme
DB00703MethazolamideCarbonic anhydrase 4target
DB00703MethazolamideCarbonic anhydrase 2target
DB00703MethazolamideCarbonic anhydrase 7target
DB00703MethazolamideCarbonic anhydrase 3target
DB00705DelavirdineCytochrome P450 3A4enzyme
DB00705DelavirdineCytochrome P450 2C9enzyme
DB00705DelavirdineCytochrome P450 2D6enzyme
DB00705DelavirdineCytochrome P450 3A5enzyme
DB00705DelavirdineCytochrome P450 3A7enzyme
DB00705DelavirdineCytochrome P450 2C19enzyme
DB00705DelavirdineCytochrome P450 2C8enzyme
DB00705DelavirdineReverse transcriptase/RNaseHtarget
DB00709LamivudineDNAtarget
DB00709LamivudineProtein Ptarget
DB00709LamivudineMultidrug resistance-associated protein 1transporter
DB00709LamivudineSolute carrier family 22 member 6transporter
DB00709LamivudineATP-binding cassette sub-family G member 2transporter
DB00709LamivudineReverse transcriptase/RNaseHtarget
DB00709LamivudineSolute carrier family 22 member 1transporter
DB00709LamivudineSolute carrier family 22 member 2transporter
DB00709LamivudineSolute carrier family 22 member 3transporter
DB00709LamivudineDeoxycytidine kinaseenzyme
DB00709LamivudineUMP-CMP kinaseenzyme
DB00709LamivudinePhosphoglycerate kinase 1enzyme
DB00709LamivudineNucleoside diphosphate kinase Aenzyme
DB00709LamivudineNucleoside diphosphate kinase Benzyme
DB00709LamivudineCholine-phosphate cytidylyltransferase Aenzyme
DB00709LamivudineEthanolamine-phosphate cytidylyltransferaseenzyme
DB00709LamivudineMultidrug resistance protein 1transporter
DB00709LamivudineMultidrug resistance-associated protein 4transporter
DB00709LamivudineCanalicular multispecific organic anion transporter 2transporter
DB00709LamivudineCanalicular multispecific organic anion transporter 1transporter
DB00709Lamivudine5'(3')-deoxyribonucleotidase, cytosolic typeenzyme
DB00709LamivudineSerum albumincarrier
DB00711DiethylcarbamazineArachidonate 5-lipoxygenasetarget
DB00711DiethylcarbamazineProstaglandin G/H synthase 1target
DB00711DiethylcarbamazineCholinesteraseenzyme
DB00712FlurbiprofenProstaglandin G/H synthase 2target
DB00712FlurbiprofenProstaglandin G/H synthase 1target
DB00712FlurbiprofenCytochrome P450 2C9enzyme
DB00712FlurbiprofenSerum albumincarrier
DB00712FlurbiprofenMultidrug resistance-associated protein 4transporter
DB00712FlurbiprofenSolute carrier family 22 member 6transporter
DB00712FlurbiprofenUDP-glucuronosyltransferase 2B7enzyme
DB00712FlurbiprofenUDP-glucuronosyltransferase 1-1enzyme
DB00712FlurbiprofenUDP-glucuronosyltransferase 1-3enzyme
DB00712FlurbiprofenUDP-glucuronosyltransferase 1-9enzyme
DB00712FlurbiprofenUDP-glucuronosyltransferase 2B4enzyme
DB00715ParoxetineSodium-dependent serotonin transportertarget
DB00715ParoxetineSodium-dependent noradrenaline transportertarget
DB00715Paroxetine5-hydroxytryptamine receptor 2Atarget
DB00715ParoxetineCytochrome P450 2D6enzyme
DB00715ParoxetineMuscarinic acetylcholine receptor M1target
DB00715ParoxetineMuscarinic acetylcholine receptor M2target
DB00715ParoxetineMuscarinic acetylcholine receptor M3target
DB00715ParoxetineMuscarinic acetylcholine receptor M4target
DB00715ParoxetineMuscarinic acetylcholine receptor M5target
DB00715ParoxetineCytochrome P450 2C9enzyme
DB00715ParoxetineMultidrug resistance protein 1transporter
DB00715ParoxetineCytochrome P450 2B6enzyme
DB00715ParoxetineCytochrome P450 2C8enzyme
DB00715ParoxetineCytochrome P450 1A2enzyme
DB00715ParoxetineCytochrome P450 3A4enzyme
DB00718Adefovir DipivoxilDNA polymerase/reverse transcriptasetarget
DB00718Adefovir DipivoxilSolute carrier family 22 member 6transporter
DB00718Adefovir DipivoxilMultidrug resistance-associated protein 4transporter
DB00718Adefovir DipivoxilMultidrug resistance-associated protein 5transporter
DB00718Adefovir DipivoxilSolute carrier family 22 member 3transporter
DB00718Adefovir DipivoxilAdenylate kinase 2, mitochondrialenzyme
DB00718Adefovir DipivoxilAdenylate kinase 4, mitochondrialenzyme
DB00718Adefovir DipivoxilNucleoside diphosphate kinase Aenzyme
DB00718Adefovir DipivoxilNucleoside diphosphate kinase Benzyme
DB00722LisinoprilAngiotensin-converting enzymetarget
DB00736EsomeprazolePotassium-transporting ATPase alpha chain 1target
DB00736EsomeprazoleCytochrome P450 2C19enzyme
DB00736EsomeprazoleCytochrome P450 3A4enzyme
DB00744ZileutonArachidonate 5-lipoxygenasetarget
DB00744ZileutonCytochrome P450 2C9enzyme
DB00744ZileutonCytochrome P450 1A2enzyme
DB00744ZileutonCytochrome P450 3A4enzyme
DB00744ZileutonProstaglandin G/H synthase 1enzyme
DB00744ZileutonUDP-glucuronosyltransferase 1-9enzyme
DB00744ZileutonSerum albumincarrier
DB00749EtodolacProstaglandin G/H synthase 1target
DB00749EtodolacProstaglandin G/H synthase 2target
DB00749EtodolacCytochrome P450 2C9enzyme
DB00749EtodolacUDP-glucuronosyltransferase 1-9enzyme
DB00749EtodolacRetinoic acid receptor RXR-alphatarget
DB00749EtodolacSerum albumincarrier
DB00749EtodolacSolute carrier family 22 member 6transporter
DB00749EtodolacUDP-glucuronosyltransferase 1-3enzyme
DB00749EtodolacUDP-glucuronosyltransferase 1-10enzyme
DB00749EtodolacUDP-glucuronosyltransferase 2B7enzyme
DB00752TranylcypromineAmine oxidase [flavin-containing] Btarget
DB00752TranylcypromineAmine oxidase [flavin-containing] Atarget
DB00752TranylcypromineCytochrome P450 2C19enzyme
DB00752TranylcypromineCytochrome P450 2A6enzyme
DB00752TranylcypromineCytochrome P450 2D6enzyme
DB00752TranylcypromineCytochrome P450 1A2enzyme
DB00752TranylcypromineCytochrome P450 2C9enzyme
DB00752TranylcypromineCytochrome P450 2E1enzyme
DB00752TranylcypromineCytochrome P450 3A4enzyme
DB00759Tetracycline16S rRNAtarget
DB00759TetracyclineMajor prion proteintarget
DB00759TetracyclineSerum albumincarrier
DB00759TetracyclineCytochrome P450 3A4enzyme
DB00759TetracyclineSolute carrier family 22 member 6transporter
DB00759TetracyclineSolute carrier family 22 member 8transporter
DB00759TetracyclineSolute carrier family 22 member 11transporter
DB00759TetracyclineSolute carrier family 22 member 7transporter
DB00759Tetracycline30S ribosomal protein S3target
DB00759Tetracycline30S ribosomal protein S8target
DB00759Tetracycline30S ribosomal protein S19target
DB00759Tetracycline30S ribosomal protein S14target
DB00759Tetracycline30S ribosomal protein S7target
DB00759TetracyclineMultidrug translocase MdfAtarget
DB00759TetracyclineProtein-arginine deiminase type-4target
DB00759TetracyclineSolute carrier organic anion transporter family member 2B1transporter
DB00762IrinotecanDNA topoisomerase I, mitochondrialtarget
DB00762IrinotecanDNA topoisomerase 1target
DB00762IrinotecanCytochrome P450 3A4enzyme
DB00762IrinotecanCytochrome P450 3A5enzyme
DB00762IrinotecanUDP-glucuronosyltransferase 1-1enzyme
DB00762IrinotecanUDP-glucuronosyltransferase 1-9enzyme
DB00762IrinotecanLiver carboxylesterase 1enzyme
DB00762IrinotecanCytochrome P450 3A7enzyme
DB00762IrinotecanCytochrome P450 2B6enzyme
DB00762IrinotecanSolute carrier family 22 member 3transporter
DB00762IrinotecanSolute carrier organic anion transporter family member 1B1transporter
DB00762IrinotecanMultidrug resistance-associated protein 1transporter
DB00762IrinotecanATP-binding cassette sub-family G member 2transporter
DB00762IrinotecanSerum albumincarrier
DB00762IrinotecanCocaine esteraseenzyme
DB00762IrinotecanCholinesteraseenzyme
DB00762IrinotecanMultidrug resistance protein 1transporter
DB00762IrinotecanCanalicular multispecific organic anion transporter 1transporter
DB00765MetyrosineTyrosine 3-monooxygenasetarget
DB00766Clavulanic acidBeta-lactamasetarget
DB00772MalathionCholinesterasetarget
DB00772MalathionCytochrome P450 1A2enzyme
DB00772MalathionCytochrome P450 2B6enzyme
DB00773EtoposideDNA topoisomerase 2-alphatarget
DB00773EtoposideCytochrome P450 3A4enzyme
DB00773EtoposideCanalicular multispecific organic anion transporter 2transporter
DB00773EtoposideMultidrug resistance-associated protein 6transporter
DB00773EtoposideMultidrug resistance protein 1transporter
DB00773EtoposideMultidrug resistance-associated protein 1transporter
DB00773EtoposideMultidrug resistance-associated protein 7transporter
DB00773EtoposideCanalicular multispecific organic anion transporter 1transporter
DB00773EtoposideATP-binding cassette sub-family G member 2transporter
DB00773EtoposideCytochrome P450 1A2enzyme
DB00773EtoposideCytochrome P450 2C8enzyme
DB00773EtoposideCytochrome P450 2E1enzyme
DB00773EtoposideCytochrome P450 3A5enzyme
DB00773EtoposideUDP-glucuronosyltransferase 1-1enzyme
DB00773EtoposideDNA topoisomerase 2-betatarget
DB00773EtoposideGlutathione S-transferase theta-1enzyme
DB00773EtoposideGlutathione S-transferase Penzyme
DB00773EtoposideProstaglandin G/H synthase 2enzyme
DB00773EtoposideProstaglandin G/H synthase 1enzyme
DB00779Nalidixic acidDNAtarget
DB00779Nalidixic acidSolute carrier family 22 member 6transporter
DB00779Nalidixic acidTryptophan 2,3-dioxygenaseenzyme
DB00780PhenelzineMembrane primary amine oxidasetarget
DB00780PhenelzineAmine oxidase [flavin-containing] Btarget
DB00780PhenelzineAmine oxidase [flavin-containing] Atarget
DB00780PhenelzineAmine oxidase [flavin-containing] Aenzyme
DB00780PhenelzineAmine oxidase [flavin-containing] Benzyme
DB00780PhenelzineCytochrome P450 2E1enzyme
DB00780Phenelzine4-aminobutyrate aminotransferase, mitochondrialtarget
DB00780PhenelzineGlutamic acid decarboxylasetarget
DB00780PhenelzineAlanine aminotransferase 1target
DB00780PhenelzineAlanine aminotransferase 2target
DB00780PhenelzineCytochrome P450 2C19enzyme
DB00780PhenelzineCytochrome P450 2C8enzyme
DB00780PhenelzineCytochrome P450 3A4enzyme
DB00780PhenelzineCytochrome P450 3A43enzyme
DB00780PhenelzineCytochrome P450 3A5enzyme
DB00780PhenelzineCytochrome P450 3A7enzyme
DB00780PhenelzineCytochrome P450 2D6enzyme
DB00784Mefenamic acidProstaglandin G/H synthase 2target
DB00784Mefenamic acidProstaglandin G/H synthase 1target
DB00784Mefenamic acidCytochrome P450 2C9enzyme
DB00784Mefenamic acidCytochrome P450 2C8enzyme
DB00784Mefenamic acidSerum albumincarrier
DB00784Mefenamic acidUDP-glucuronosyltransferase 1-9enzyme
DB00786Marimastat72 kDa type IV collagenasetarget
DB00786MarimastatMatrix metalloproteinase-9target
DB00786MarimastatStromelysin-1target
DB00786MarimastatInterstitial collagenasetarget
DB00786MarimastatStromelysin-2target
DB00786MarimastatMatrilysintarget
DB00786MarimastatNeutrophil collagenasetarget
DB00786MarimastatStromelysin-3target
DB00786MarimastatMacrophage metalloelastasetarget
DB00786MarimastatCollagenase 3target
DB00786MarimastatMatrix metalloproteinase-14target
DB00786MarimastatMatrix metalloproteinase-15target
DB00786MarimastatMatrix metalloproteinase-16target
DB00786MarimastatMatrix metalloproteinase-17target
DB00786MarimastatMatrix metalloproteinase-19target
DB00786MarimastatMatrix metalloproteinase-20target
DB00786MarimastatMatrix metalloproteinase-21target
DB00786MarimastatMatrix metalloproteinase-23target
DB00786MarimastatMatrix metalloproteinase-24target
DB00786MarimastatMatrix metalloproteinase-25target
DB00786MarimastatMatrix metalloproteinase-26target
DB00786MarimastatMatrix metalloproteinase-27target
DB00786MarimastatMatrix metalloproteinase-28target
DB00788NaproxenProstaglandin G/H synthase 1target
DB00788NaproxenProstaglandin G/H synthase 2target
DB00788NaproxenSerum albumincarrier
DB00788NaproxenCytochrome P450 2C9enzyme
DB00788NaproxenCytochrome P450 1A2enzyme
DB00788NaproxenSolute carrier organic anion transporter family member 1A2transporter
DB00788NaproxenSolute carrier family 22 member 6transporter
DB00788NaproxenCytochrome P450 2C8enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-1enzyme
DB00788NaproxenUDP-glucuronosyltransferase 2B7enzyme
DB00788NaproxenPeptostreptococcal albumin-binding proteintarget
DB00788NaproxenBile salt export pumptransporter
DB00788NaproxenMultidrug resistance protein 1transporter
DB00790PerindoprilAngiotensin-converting enzymetarget
DB00790PerindoprilSolute carrier family 15 member 1transporter
DB00790PerindoprilSolute carrier family 15 member 2transporter
DB00790PerindoprilCholinesteraseenzyme
DB00790PerindoprilSecreted frizzled-related protein 4target
DB00798Gentamicin30S ribosomal protein S12target
DB00798Gentamicin16S rRNAtarget
DB00798GentamicinLow-density lipoprotein receptor-related protein 2target
DB00798GentamicinSolute carrier family 22 member 6transporter
DB00798GentamicinNH(3)-dependent NAD(+) synthetasetarget
DB00798GentamicinDihydrofolate reductasetarget
DB00806PentoxifyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB00806PentoxifyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB00806Pentoxifylline5'-nucleotidasetarget
DB00806PentoxifyllinecGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00806PentoxifyllineAdenosine receptor A1target
DB00806PentoxifyllineAdenosine receptor A2atarget
DB00806PentoxifyllineCytochrome P450 1A2enzyme
DB00814MeloxicamProstaglandin G/H synthase 2target
DB00814MeloxicamCytochrome P450 2C9enzyme
DB00814MeloxicamProstaglandin G/H synthase 1target
DB00814MeloxicamCytochrome P450 3A4enzyme
DB00814MeloxicamMultidrug resistance-associated protein 4transporter
DB00814Meloxicam6-phosphogluconate dehydrogenase, decarboxylatingenzyme
DB00814MeloxicamCytochrome P450 2C8enzyme
DB00819AcetazolamideCarbonic anhydrase 1target
DB00819AcetazolamideAquaporin-1target
DB00819AcetazolamideCarbonic anhydrase 14target
DB00819AcetazolamideSolute carrier family 22 member 6transporter
DB00819AcetazolamideCarbonic anhydrase 2target
DB00819AcetazolamideCarbonic anhydrase 3target
DB00819AcetazolamideCarbonic anhydrase 4target
DB00819AcetazolamideCytochrome P450 3A4enzyme
DB00819AcetazolamideCarbonic anhydrase 7target
DB00819AcetazolamideCarbonic anhydrase 12target
DB00820TadalafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00820TadalafilCytochrome P450 3A4enzyme
DB00820TadalafilDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11Atarget
DB00820TadalafilCytochrome P450 3A5enzyme
DB00822DisulfiramAldehyde dehydrogenase, mitochondrialtarget
DB00822DisulfiramCytochrome P450 2E1enzyme
DB00822DisulfiramDopamine beta-hydroxylasetarget
DB00822DisulfiramCytochrome P450 3A4enzyme
DB00822DisulfiramCytochrome P450 3A5enzyme
DB00822DisulfiramBile salt export pumptransporter
DB00827CinoxacinDNAtarget
DB00827CinoxacinDNA gyrase subunit Atarget
DB00827CinoxacinSolute carrier family 22 member 6transporter
DB00827CinoxacinCytochrome P450 1A2enzyme
DB00843DonepezilAcetylcholinesterasetarget
DB00843Donepezil5-hydroxytryptamine receptor 2Atarget
DB00843DonepezilCytochrome P450 3A4enzyme
DB00843DonepezilCytochrome P450 2D6enzyme
DB00843DonepezilCytochrome P450 2C9enzyme
DB00857TerbinafineSqualene monooxygenasetarget
DB00857TerbinafineCytochrome P450 2D6enzyme
DB00857TerbinafineCytochrome P450 2C9enzyme
DB00857TerbinafineCytochrome P450 1A2enzyme
DB00857TerbinafineCytochrome P450 3A4enzyme
DB00857TerbinafineCytochrome P450 2C8enzyme
DB00857TerbinafineCytochrome P450 2C19enzyme
DB00857TerbinafineProstaglandin G/H synthase 1enzyme
DB00857TerbinafineCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB00857TerbinafineCytochrome P450 19A1enzyme
DB00861DiflunisalProstaglandin G/H synthase 1target
DB00861DiflunisalProstaglandin G/H synthase 2target
DB00861DiflunisalTransthyretincarrier
DB00861DiflunisalSerum albumincarrier
DB00861DiflunisalSolute carrier family 22 member 6transporter
DB00861DiflunisalUDP-glucuronosyltransferase 1-8enzyme
DB00861DiflunisalUDP-glucuronosyltransferase 1-9enzyme
DB00862VardenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00862VardenafilCytochrome P450 3A4enzyme
DB00862VardenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00862VardenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB00862VardenafilCytochrome P450 3A5enzyme
DB00862VardenafilMultidrug resistance protein 1transporter
DB00864TacrolimusPeptidyl-prolyl cis-trans isomerase FKBP1Atarget
DB00864TacrolimusCytochrome P450 3A4enzyme
DB00864TacrolimusCytochrome P450 3A5enzyme
DB00864TacrolimusCytochrome P450 3A7enzyme
DB00864TacrolimusMultidrug resistance protein 1transporter
DB00864TacrolimusATP-binding cassette sub-family A member 5transporter
DB00864TacrolimusSerum albumincarrier
DB00864TacrolimusAlpha-1-acid glycoprotein 1carrier
DB00864TacrolimusSolute carrier organic anion transporter family member 1B1transporter
DB00869DorzolamideCarbonic anhydrase 2target
DB00869DorzolamideCarbonic anhydrase 1target
DB00869DorzolamideCarbonic anhydrase 4target
DB00869DorzolamideCytochrome P450 2C9enzyme
DB00869DorzolamideCytochrome P450 3A4enzyme
DB00869DorzolamideCarbonic anhydrase 3target
DB00870SuprofenProstaglandin G/H synthase 1target
DB00870SuprofenProstaglandin G/H synthase 2target
DB00870SuprofenCytochrome P450 2C9enzyme
DB00870SuprofenUDP-glucuronosyltransferase 1-1enzyme
DB00870SuprofenUDP-glucuronosyltransferase 2B7enzyme
DB00879EmtricitabineReverse transcriptase/RNaseHtarget
DB00879EmtricitabineDeoxycytidine kinaseenzyme
DB00879EmtricitabineSerum albumincarrier
DB00881QuinaprilAngiotensin-converting enzymetarget
DB00881QuinaprilSolute carrier family 15 member 1transporter
DB00881QuinaprilSolute carrier family 15 member 2transporter
DB00881QuinaprilSolute carrier family 22 member 8transporter
DB00886OmapatrilatNeprilysintarget
DB00886OmapatrilatAngiotensin-converting enzymetarget
DB00900DidanosineSolute carrier family 22 member 6transporter
DB00900DidanosinePurine nucleoside phosphorylasetarget
DB00900DidanosineReverse transcriptase/RNaseHtarget
DB00900DidanosineEquilibrative nucleoside transporter 1transporter
DB00900DidanosineEquilibrative nucleoside transporter 2transporter
DB00900DidanosineSerum albumincarrier
DB00903Etacrynic acidSolute carrier family 12 member 1target
DB00903Etacrynic acidSodium/potassium-transporting ATPase subunit alpha-1target
DB00903Etacrynic acidGlutathione S-transferase A2enzyme
DB00903Etacrynic acidSerum albumincarrier
DB00903Etacrynic acidSolute carrier family 22 member 6transporter
DB00903Etacrynic acidLymphoid enhancer-binding factor 1target
DB00903Etacrynic acidGlutathione S-transferase Ptarget
DB00908QuinidineSodium channel protein type 5 subunit alphatarget
DB00908QuinidineAlpha-1-acid glycoprotein 1carrier
DB00908QuinidinePotassium voltage-gated channel subfamily H member 2target
DB00908QuinidinePotassium channel subfamily K member 1target
DB00908QuinidinePotassium channel subfamily K member 6target
DB00908QuinidineCytochrome P450 1A2enzyme
DB00908QuinidineCytochrome P450 2E1enzyme
DB00908QuinidineCytochrome P450 1A1enzyme
DB00908QuinidineCytochrome P450 2D6enzyme
DB00908QuinidineCytochrome P450 3A4enzyme
DB00908QuinidineCytochrome P450 3A7enzyme
DB00908QuinidineSolute carrier family 22 member 2transporter
DB00908QuinidineSolute carrier family 22 member 1transporter
DB00908QuinidineSolute carrier family 22 member 5transporter
DB00908QuinidineMultidrug resistance protein 1transporter
DB00908QuinidineSolute carrier organic anion transporter family member 1A2transporter
DB00908QuinidineSolute carrier family 22 member 8transporter
DB00908QuinidineCanalicular multispecific organic anion transporter 1transporter
DB00908QuinidineSolute carrier family 22 member 4transporter
DB00908QuinidineSolute carrier organic anion transporter family member 1B1transporter
DB00908QuinidineCytochrome P450 2B6enzyme
DB00908QuinidineCytochrome P450 2C9enzyme
DB00908QuinidineAlpha-1A adrenergic receptortarget
DB00908QuinidineAlpha-1B adrenergic receptortarget
DB00908QuinidineAlpha-1D adrenergic receptortarget
DB00908QuinidineBile salt export pumptransporter
DB00908QuinidineCytochrome P450 2C8enzyme
DB00922LevosimendanTroponin C, slow skeletal and cardiac musclestarget
DB00922LevosimendanATP-sensitive inward rectifier potassium channel 11target
DB00922LevosimendanATP-sensitive inward rectifier potassium channel 8target
DB00922LevosimendancGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB00928AzacitidineDNA (cytosine-5)-methyltransferase 1target
DB00928AzacitidineCytidine deaminaseenzyme
DB00928AzacitidineDNAtarget
DB00928AzacitidineRNAtarget
DB00936Salicylic acidSerum albumincarrier
DB00936Salicylic acidProstaglandin G/H synthase 1target
DB00936Salicylic acidProstaglandin G/H synthase 2target
DB00936Salicylic acidAldo-keto reductase family 1 member C1target
DB00936Salicylic acidSolute carrier family 22 member 6transporter
DB00936Salicylic acidSolute carrier family 22 member 10transporter
DB00936Salicylic acidSolute carrier family 22 member 8transporter
DB00936Salicylic acidSolute carrier family 22 member 11transporter
DB00936Salicylic acidSolute carrier organic anion transporter family member 2B1transporter
DB00936Salicylic acidMonocarboxylate transporter 1transporter
DB00936Salicylic acidSolute carrier family 22 member 7transporter
DB00936Salicylic acidCytochrome P450 2C9enzyme
DB00939Meclofenamic acidProstaglandin G/H synthase 1target
DB00939Meclofenamic acidProstaglandin G/H synthase 2target
DB00939Meclofenamic acidArachidonate 5-lipoxygenasetarget
DB00939Meclofenamic acidSolute carrier family 22 member 6transporter
DB00939Meclofenamic acidSolute carrier organic anion transporter family member 1C1transporter
DB00939Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 2target
DB00939Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 3target
DB00943ZalcitabineDeoxycytidine kinaseenzyme
DB00943ZalcitabineSolute carrier family 22 member 6transporter
DB00943ZalcitabineSolute carrier family 22 member 7transporter
DB00943ZalcitabineReverse transcriptase/RNaseHtarget
DB00943ZalcitabineEquilibrative nucleoside transporter 1transporter
DB00943ZalcitabineEquilibrative nucleoside transporter 2transporter
DB00943ZalcitabineSerum albumincarrier
DB00944DemecariumAcetylcholinesterasetarget
DB00944DemecariumCholinesterasetarget
DB00945Acetylsalicylic acidProstaglandin G/H synthase 1target
DB00945Acetylsalicylic acidProstaglandin G/H synthase 2target
DB00945Acetylsalicylic acidSerum albumincarrier
DB00945Acetylsalicylic acidAldo-keto reductase family 1 member C1target
DB00945Acetylsalicylic acidSolute carrier family 22 member 6transporter
DB00945Acetylsalicylic acidMultidrug resistance protein 1transporter
DB00945Acetylsalicylic acidSolute carrier family 22 member 7transporter
DB00945Acetylsalicylic acidCytochrome P450 2C19enzyme
DB00945Acetylsalicylic acidCytochrome P450 2C8enzyme
DB00945Acetylsalicylic acidCytochrome P450 2C9enzyme
DB00945Acetylsalicylic acid5'-AMP-activated protein kinasetarget
DB00945Acetylsalicylic acidEndothelin-1 receptortarget
DB00945Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00945Acetylsalicylic acidCellular tumor antigen p53target
DB00945Acetylsalicylic acid78 kDa glucose-regulated proteintarget
DB00945Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
DB00945Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
DB00945Acetylsalicylic acidNuclear factor NF-kappa-Btarget
DB00955Netilmicin30S ribosomal protein S12target
DB00955Netilmicin16S rRNAtarget
DB00970DactinomycinDNAtarget
DB00970DactinomycinSolute carrier family 22 member 5transporter
DB00970DactinomycinMultidrug resistance protein 1transporter
DB00970DactinomycinMultidrug resistance-associated protein 6transporter
DB00970DactinomycinMultidrug resistance-associated protein 1transporter
DB00970DactinomycinATP-binding cassette sub-family G member 2transporter
DB00970DactinomycinDNA topoisomerase 2target
DB00972AzelastineHistamine H1 receptortarget
DB00972AzelastineCytochrome P450 1A2enzyme
DB00972AzelastineCytochrome P450 2D6enzyme
DB00972AzelastineCytochrome P450 3A4enzyme
DB00972AzelastineCytochrome P450 2C19enzyme
DB00972AzelastineCytochrome P450 1A1enzyme
DB00972AzelastineCytochrome P450 3A5enzyme
DB00972AzelastineCytochrome P450 2C9enzyme
DB00972AzelastineCytochrome P450 2C8enzyme
DB00972AzelastineMultidrug resistance protein 1transporter
DB00972AzelastineCytochrome P450 2A6enzyme
DB00972AzelastineCytochrome P450 2B6enzyme
DB00972AzelastineCytochrome P450 2E1enzyme
DB00975DipyridamolecAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
DB00975DipyridamolecGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00975DipyridamolecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB00975DipyridamoleAdenosine deaminasetarget
DB00975DipyridamoleMultidrug resistance-associated protein 4transporter
DB00975DipyridamoleMultidrug resistance-associated protein 5transporter
DB00975DipyridamoleMultidrug resistance protein 1transporter
DB00975DipyridamoleCalcipressin-1target
DB00975DipyridamoleAlpha-1-acid glycoprotein 1target
DB00975DipyridamoleSolute carrier organic anion transporter family member 1B1transporter
DB00975DipyridamoleSolute carrier organic anion transporter family member 1B3transporter
DB00975DipyridamoleSolute carrier organic anion transporter family member 2B1transporter
DB00975DipyridamoleBile salt export pumptransporter
DB00978LomefloxacinDNA gyrase subunit Atarget
DB00978LomefloxacinDNA topoisomerase 4 subunit Atarget
DB00978LomefloxacinDNA topoisomerase 2-alphatarget
DB00978LomefloxacinCytochrome P450 1A2enzyme
DB00978LomefloxacinSolute carrier family 22 member 5transporter
DB00978LomefloxacinCanalicular multispecific organic anion transporter 1transporter
DB00981PhysostigmineAcetylcholinesterasetarget
DB00981PhysostigmineNeuronal acetylcholine receptor subunit alpha-4target
DB00981PhysostigmineNeuronal acetylcholine receptor subunit beta-2target
DB00989RivastigmineAcetylcholinesterasetarget
DB00989RivastigmineCholinesterasetarget
DB00989RivastigmineCytochrome P450 3A4enzyme
DB00990ExemestaneCytochrome P450 19A1target
DB00990ExemestaneCytochrome P450 3A4enzyme
DB00990ExemestaneCytochrome P450 19A1enzyme
DB00994Neomycin30S ribosomal protein S12target
DB00994Neomycin16S rRNAtarget
DB00994NeomycinExtracellular calcium-sensing receptortarget
DB00997DoxorubicinDNA topoisomerase 2-alphatarget
DB00997DoxorubicinDNAtarget
DB00997DoxorubicinCytochrome P450 3A4enzyme
DB00997DoxorubicinCytochrome P450 2D6enzyme
DB00997DoxorubicinCytochrome P450 2B6enzyme
DB00997DoxorubicinMultidrug resistance protein 1transporter
DB00997DoxorubicinCanalicular multispecific organic anion transporter 2transporter
DB00997DoxorubicinMultidrug resistance-associated protein 6transporter
DB00997DoxorubicinMultidrug resistance-associated protein 1transporter
DB00997DoxorubicinMultidrug resistance-associated protein 7transporter
DB00997DoxorubicinATP-binding cassette sub-family G member 2transporter
DB00997DoxorubicinBile salt export pumptransporter
DB00997DoxorubicinSolute carrier family 22 member 16transporter
DB00997DoxorubicinATP-binding cassette sub-family B member 8, mitochondrialtransporter
DB00997DoxorubicinCytochrome P450 1B1enzyme
DB00997DoxorubicinCarbonyl reductase [NADPH] 1enzyme
DB00997DoxorubicinCarbonyl reductase [NADPH] 3enzyme
DB00997DoxorubicinAlcohol dehydrogenase [NADP(+)]enzyme
DB00997DoxorubicinAldo-keto reductase family 1 member C3enzyme
DB00997DoxorubicinNAD(P)H dehydrogenase [quinone] 1enzyme
DB00997DoxorubicinXanthine dehydrogenase/oxidaseenzyme
DB00997DoxorubicinNitric oxide synthase, endothelialenzyme
DB00997DoxorubicinNitric oxide synthase, inducibleenzyme
DB00997DoxorubicinNitric oxide synthase, brainenzyme
DB00997DoxorubicinNADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrialenzyme
DB00997DoxorubicinNADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrialenzyme
DB00997DoxorubicinNADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrialenzyme
DB00997DoxorubicinNADPH--cytochrome P450 reductaseenzyme
DB00997DoxorubicinRalA-binding protein 1transporter
DB00997DoxorubicinCanalicular multispecific organic anion transporter 1transporter
DB00997DoxorubicinSerum albumincarrier
DB00997DoxorubicinNucleolar and coiled-body phosphoprotein 1target
DB01005HydroxyureaRibonucleoside-diphosphate reductase large subunittarget
DB01005HydroxyureaCytochrome P450 2D6enzyme
DB01006LetrozoleCytochrome P450 19A1target
DB01006LetrozoleCytochrome P450 3A4enzyme
DB01006LetrozoleCytochrome P450 2A6enzyme
DB01006LetrozoleCytochrome P450 19A1enzyme
DB01007TioconazoleLanosterol 14-alpha demethylasetarget
DB01007TioconazoleCytochrome P450 19A1enzyme
DB01007TioconazoleCytochrome P450 2C19enzyme
DB01007TioconazoleCytochrome P450 2C8enzyme
DB01007TioconazoleCytochrome P450 2E1enzyme
DB01007TioconazoleCytochrome P450 3A4enzyme
DB01007TioconazoleLanosterol 14-alpha demethylasetarget
DB01009KetoprofenProstaglandin G/H synthase 1target
DB01009KetoprofenProstaglandin G/H synthase 2target
DB01009KetoprofenC-X-C chemokine receptor type 1target
DB01009KetoprofenSerum albumincarrier
DB01009KetoprofenMultidrug resistance-associated protein 4transporter
DB01009KetoprofenSolute carrier organic anion transporter family member 1A2transporter
DB01009KetoprofenSolute carrier family 22 member 6transporter
DB01009KetoprofenSolute carrier family 22 member 8transporter
DB01009KetoprofenSolute carrier family 22 member 11transporter
DB01009KetoprofenSolute carrier family 22 member 7transporter
DB01009KetoprofenCytochrome P450 2C9enzyme
DB01009KetoprofenCytochrome P450 2C8enzyme
DB01009KetoprofenUDP-glucuronosyltransferase 1-1enzyme
DB01010EdrophoniumAcetylcholinesterasetarget
DB01010EdrophoniumCholinesterasetarget
DB01011MetyraponeCamphor 5-monooxygenasetarget
DB01011MetyraponeCytochrome P450 11B2, mitochondrialenzyme
DB01011MetyraponeCytochrome P450 2A6enzyme
DB01011MetyraponeCytochrome P450 3A4enzyme
DB01011MetyraponeCanalicular multispecific organic anion transporter 2transporter
DB01011MetyraponeCytochrome P450 11B1, mitochondrialtarget
DB01011MetyraponeCytochrome P450 11B1, mitochondrialenzyme
DB01011MetyraponeCytochrome P450 2E1enzyme
DB01024Mycophenolic acidInosine-5'-monophosphate dehydrogenase 2target
DB01024Mycophenolic acidInosine-5'-monophosphate dehydrogenase 1target
DB01024Mycophenolic acidUDP-glucuronosyltransferase 1-1enzyme
DB01024Mycophenolic acidUDP-glucuronosyltransferase 1-9enzyme
DB01024Mycophenolic acidUDP-glucuronosyltransferase 2B7enzyme
DB01024Mycophenolic acidUDP-glucuronosyltransferase 1-7enzyme
DB01024Mycophenolic acidUDP-glucuronosyltransferase 1-6enzyme
DB01026KetoconazoleCytochrome P450 3A4enzyme
DB01026KetoconazoleCytochrome P450 2C9enzyme
DB01026KetoconazoleCytochrome P450 2C19enzyme
DB01026KetoconazoleCytochrome P450 3A5enzyme
DB01026KetoconazoleCytochrome P450 1A2enzyme
DB01026KetoconazoleCytochrome P450 2C8enzyme
DB01026KetoconazoleCytochrome P450 1A1enzyme
DB01026KetoconazoleCytochrome P450 2D6enzyme
DB01026KetoconazoleCytochrome P450 3A7enzyme
DB01026KetoconazoleBile salt export pumptransporter
DB01026KetoconazoleMultidrug resistance protein 1transporter
DB01026KetoconazoleSolute carrier organic anion transporter family member 1A2transporter
DB01026KetoconazoleCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB01026KetoconazoleCytochrome P450 11B1, mitochondrialenzyme
DB01026KetoconazoleCytochrome P450 1B1enzyme
DB01026KetoconazoleCytochrome P450 26A1enzyme
DB01026KetoconazoleCytochrome P450 2A6enzyme
DB01026KetoconazoleCytochrome P450 2B6enzyme
DB01026KetoconazoleLanosterol 14-alpha demethylaseenzyme
DB01026KetoconazoleLanosterol 14-alpha demethylasetarget
DB01026KetoconazoleAndrogen receptortarget
DB01026Ketoconazole17-hydroxylasetarget
DB01026KetoconazoleSteroid 21-hydroxylasetarget
DB01026Ketoconazole11-hydroxylasetarget
DB01026KetoconazoleCytochrome P450 19A1target
DB01026KetoconazolePotassium voltage-gated channel subfamily H member 2target
DB01026KetoconazoleNuclear receptor subfamily 1 group I member 2target
DB01026KetoconazoleNuclear receptor subfamily 1 group I member 3target
DB01026KetoconazoleUDP-glucuronosyltransferase 1-1enzyme
DB01026KetoconazoleUDP-glucuronosyltransferase 2B7enzyme
DB01026KetoconazoleSolute carrier organic anion transporter family member 1B1transporter
DB01026KetoconazoleCytochrome P450 4F12enzyme
DB01026KetoconazoleLeukotriene-B(4) omega-hydroxylase 1enzyme
DB01030TopotecanDNA topoisomerase I, mitochondrialtarget
DB01030TopotecanDNA topoisomerase 1target
DB01030TopotecanATP-binding cassette sub-family G member 2transporter
DB01030TopotecanMultidrug resistance protein 1transporter
DB01030TopotecanCytochrome P450 3A4enzyme
DB01030TopotecanDNAtarget
DB01030TopotecanMultidrug and toxin extrusion protein 1transporter
DB01030TopotecanMultidrug and toxin extrusion protein 2transporter
DB01033MercaptopurineThiopurine S-methyltransferaseenzyme
DB01033MercaptopurineXanthine dehydrogenase/oxidaseenzyme
DB01033MercaptopurineHypoxanthine-guanine phosphoribosyltransferasetarget
DB01033MercaptopurineSolute carrier family 22 member 8transporter
DB01033MercaptopurineMultidrug resistance-associated protein 4transporter
DB01033MercaptopurineMultidrug resistance-associated protein 5transporter
DB01033MercaptopurineSodium/nucleoside cotransporter 2transporter
DB01033MercaptopurineSolute carrier family 28 member 3transporter
DB01033MercaptopurineEquilibrative nucleoside transporter 1transporter
DB01033MercaptopurineEquilibrative nucleoside transporter 2transporter
DB01033MercaptopurineAldehyde oxidaseenzyme
DB01033MercaptopurineAmidophosphoribosyltransferasetarget
DB01033MercaptopurineInosine-5'-monophosphate dehydrogenasetarget
DB01037SelegilineAmine oxidase [flavin-containing] Btarget
DB01037SelegilineCytochrome P450 2B6enzyme
DB01037SelegilineAmine oxidase [flavin-containing] Atarget
DB01037SelegilineCytochrome P450 2A6enzyme
DB01037SelegilineCytochrome P450 3A4enzyme
DB01037SelegilineMultidrug resistance protein 1transporter
DB01037SelegilineCytochrome P450 1A2enzyme
DB01037SelegilineCytochrome P450 2C19enzyme
DB01037SelegilineCytochrome P450 2C8enzyme
DB01037SelegilineCytochrome P450 2C9enzyme
DB01037SelegilineCytochrome P450 2D6enzyme
DB01037SelegilineCytochrome P450 2E1enzyme
DB01044GatifloxacinSerum albumincarrier
DB01044GatifloxacinDNA gyrase subunit Atarget
DB01044GatifloxacinDNA gyrase subunit Btarget
DB01044GatifloxacinDNA topoisomerase 4 subunit Atarget
DB01044GatifloxacinDNA topoisomerase 4 subunit Btarget
DB01044GatifloxacinCytochrome P450 1A2enzyme
DB01045RifampicinDNA-directed RNA polymerase subunit betatarget
DB01045RifampicinNuclear receptor subfamily 1 group I member 2target
DB01045RifampicinCytochrome P450 3A4enzyme
DB01045RifampicinCytochrome P450 1A2enzyme
DB01045RifampicinCytochrome P450 2C8enzyme
DB01045RifampicinUDP-glucuronosyltransferase 1-1enzyme
DB01045RifampicinCytochrome P450 2C9enzyme
DB01045RifampicinCytochrome P450 2B6enzyme
DB01045RifampicinCytochrome P450 2C19enzyme
DB01045RifampicinCanalicular multispecific organic anion transporter 2transporter
DB01045RifampicinMultidrug resistance-associated protein 5transporter
DB01045RifampicinMultidrug resistance protein 1transporter
DB01045RifampicinCanalicular multispecific organic anion transporter 1transporter
DB01045RifampicinSolute carrier organic anion transporter family member 2B1transporter
DB01045RifampicinBile salt export pumptransporter
DB01045RifampicinMultidrug resistance-associated protein 1transporter
DB01045RifampicinSolute carrier organic anion transporter family member 1A2transporter
DB01045RifampicinSolute carrier organic anion transporter family member 1B3transporter
DB01045RifampicinSolute carrier family 22 member 7transporter
DB01045RifampicinSolute carrier organic anion transporter family member 1B1transporter
DB01045RifampicinDNA-directed RNA polymerase subunit beta'target
DB01045RifampicinCytochrome P450 2A6enzyme
DB01045RifampicinCytochrome P450 2E1enzyme
DB01045RifampicinCytochrome P450 3A43enzyme
DB01045RifampicinCytochrome P450 3A7enzyme
DB01045RifampicinCytochrome P450 4A11enzyme
DB01045RifampicinSolute carrier organic anion transporter family member 1B1target
DB01045RifampicinSolute carrier organic anion transporter family member 1A2target
DB01045RifampicinSolute carrier organic anion transporter family member 1B3target
DB01045RifampicinLanosterol 14-alpha demethylasetarget
DB01045RifampicinSerum albumintarget
DB01045RifampicinSolute carrier organic anion transporter family member 2B1target
DB01045RifampicinCytochrome P450 2D6enzyme
DB01045RifampicinSolute carrier family 22 member 6transporter
DB01045RifampicinSolute carrier family 22 member 8transporter
DB01045RifampicinUDP-glucuronosyltransferase 1A9enzyme
DB01048AbacavirAlcohol dehydrogenase 6enzyme
DB01048AbacavirUDP-glucuronosyltransferase 1-1enzyme
DB01048AbacavirReverse transcriptase/RNaseHtarget
DB01048AbacavirAdenosine kinaseenzyme
DB01048AbacavirHLA class I histocompatibility antigen, B-57 alpha chaintarget
DB01050IbuprofenProstaglandin G/H synthase 1target
DB01050IbuprofenProstaglandin G/H synthase 2target
DB01050IbuprofenCytochrome P450 2C9enzyme
DB01050IbuprofenSerum albumincarrier
DB01050IbuprofenMultidrug resistance-associated protein 4transporter
DB01050IbuprofenMultidrug resistance-associated protein 1transporter
DB01050IbuprofenSolute carrier organic anion transporter family member 1A2transporter
DB01050IbuprofenSolute carrier family 22 member 6transporter
DB01050IbuprofenSolute carrier family 22 member 8transporter
DB01050IbuprofenSolute carrier family 22 member 11transporter
DB01050IbuprofenSolute carrier organic anion transporter family member 2B1transporter
DB01050IbuprofenMultidrug resistance protein 1transporter
DB01050IbuprofenUDP-glucuronosyltransferase 1-3enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 1-9enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 2B4enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 2B7enzyme
DB01050IbuprofenCytochrome P450 2C8enzyme
DB01050IbuprofenCytochrome P450 2C19enzyme
DB01050IbuprofenApoptosis regulator Bcl-2target
DB01050IbuprofenThrombomodulintarget
DB01050IbuprofenFatty acid-binding protein, intestinaltarget
DB01050IbuprofenPeroxisome proliferator-activated receptor gammatarget
DB01050IbuprofenCystic fibrosis transmembrane conductance regulatortarget
DB01050IbuprofenPeroxisome proliferator-activated receptor alphatarget
DB01050IbuprofenPlatelet glycoprotein Ib alpha chaintarget
DB01050IbuprofenProtein S100-A7target
DB01050IbuprofenAlpha-methylacyl-CoA racemaseenzyme
DB01051NovobiocinDNA gyrase subunit Btarget
DB01051NovobiocinSolute carrier family 22 member 6transporter
DB01051NovobiocinSolute carrier family 22 member 8transporter
DB01051NovobiocinSolute carrier family 22 member 11transporter
DB01051NovobiocinATP-binding cassette sub-family G member 2transporter
DB01051NovobiocinDNA topoisomerase 1target
DB01051NovobiocinSolute carrier organic anion transporter family member 1B1transporter
DB01051NovobiocinSolute carrier organic anion transporter family member 1B3transporter
DB01051NovobiocinSolute carrier organic anion transporter family member 2B1transporter
DB01057EchothiophateCholinesterasetarget
DB01057EchothiophateSerum albumincarrier
DB01059NorfloxacinDNA gyrase subunit Atarget
DB01059NorfloxacinDNA topoisomerase 4 subunit Atarget
DB01059NorfloxacinDNA topoisomerase 2-alphatarget
DB01059NorfloxacinCytochrome P450 1A2enzyme
DB01059NorfloxacinCytochrome P450 3A4enzyme
DB01059NorfloxacinCytochrome P450 3A5enzyme
DB01059NorfloxacinCytochrome P450 3A7enzyme
DB01059NorfloxacinSolute carrier family 22 member 5transporter
DB01059NorfloxacinSolute carrier family 22 member 6transporter
DB01059NorfloxacinCytochrome P450 1A1enzyme
DB01072AtazanavirHuman immunodeficiency virus type 1 proteasetarget
DB01072AtazanavirCytochrome P450 3A4enzyme
DB01072AtazanavirCytochrome P450 2C9enzyme
DB01072AtazanavirMultidrug resistance protein 1transporter
DB01072AtazanavirMultidrug resistance-associated protein 1transporter
DB01072AtazanavirSerum albumincarrier
DB01072AtazanavirUDP-glucuronosyltransferase 1-1enzyme
DB01072AtazanavirSolute carrier organic anion transporter family member 1B1transporter
DB01072AtazanavirSolute carrier organic anion transporter family member 1B3transporter
DB01072AtazanavirCytochrome P450 2C8enzyme
DB01072AtazanavirBile salt export pumptransporter
DB01073FludarabineDNA polymerase alpha catalytic subunittarget
DB01073FludarabineRibonucleoside-diphosphate reductase large subunittarget
DB01073FludarabineEquilibrative nucleoside transporter 1transporter
DB01073FludarabineDNAtarget
DB01073FludarabineDeoxycytidine kinasetarget
DB01073FludarabineSolute carrier family 28 member 3transporter
DB01076Atorvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB01076AtorvastatinCytochrome P450 3A4enzyme
DB01076AtorvastatinDipeptidyl peptidase 4target
DB01076AtorvastatinCytochrome P450 2D6enzyme
DB01076AtorvastatinCytochrome P450 2C9enzyme
DB01076AtorvastatinCytochrome P450 2C19enzyme
DB01076AtorvastatinCytochrome P450 3A5enzyme
DB01076AtorvastatinCytochrome P450 3A7enzyme
DB01076AtorvastatinMultidrug resistance protein 1transporter
DB01076AtorvastatinSolute carrier organic anion transporter family member 1A2transporter
DB01076AtorvastatinSolute carrier organic anion transporter family member 1B1transporter
DB01076AtorvastatinMultidrug resistance-associated protein 4transporter
DB01076AtorvastatinMultidrug resistance-associated protein 5transporter
DB01076AtorvastatinMultidrug resistance-associated protein 1transporter
DB01076AtorvastatinCytochrome P450 2B6enzyme
DB01076AtorvastatinCytochrome P450 2C8enzyme
DB01076AtorvastatinAryl hydrocarbon receptortarget
DB01076AtorvastatinSolute carrier organic anion transporter family member 2B1transporter
DB01076AtorvastatinSolute carrier organic anion transporter family member 1B3transporter
DB01076AtorvastatinUDP-glucuronosyltransferase 1-1enzyme
DB01076AtorvastatinUDP-glucuronosyltransferase 1-3enzyme
DB01076AtorvastatinUDP-glucuronosyltransferase 2B7enzyme
DB01076AtorvastatinCanalicular multispecific organic anion transporter 1transporter
DB01076AtorvastatinBile salt export pumptransporter
DB01078DeslanosideSodium/potassium-transporting ATPase subunit alpha-1target
DB01080Vigabatrin4-aminobutyrate aminotransferase, mitochondrialtarget
DB01080VigabatrinGamma-aminobutyric acid type B receptor subunit 1target
DB01080VigabatrinProton-coupled amino acid transporter 1transporter
DB01080VigabatrinCytochrome P450 2C9enzyme
DB01082Streptomycin30S ribosomal protein S12target
DB01082Streptomycin16S rRNAtarget
DB01082StreptomycinSolute carrier family 22 member 6transporter
DB01082StreptomycinProtein-arginine deiminase type-4target
DB01083OrlistatPancreatic triacylglycerol lipasetarget
DB01083OrlistatFatty acid synthasetarget
DB01083OrlistatGastric triacylglycerol lipasetarget
DB01083OrlistatCytochrome P450 3A4enzyme
DB01083OrlistatCytosolic phospholipase A2enzyme
DB01092OuabainSodium/potassium-transporting ATPase subunit alpha-1target
DB01092OuabainSolute carrier organic anion transporter family member 1A2transporter
DB01092OuabainSolute carrier family 22 member 8transporter
DB01092OuabainSolute carrier organic anion transporter family member 4C1transporter
DB01092OuabainSolute carrier organic anion transporter family member 1B3transporter
DB01092OuabainSolute carrier organic anion transporter family member 1C1transporter
DB01092OuabainSolute carrier organic anion transporter family member 1B1transporter
DB01092OuabainCytochrome P450 1A1enzyme
DB01092OuabainSodium/potassium-transporting ATPase subunit alpha-2target
DB01092OuabainSodium/potassium-transporting ATPase subunit alpha-3target
DB01095Fluvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB01095FluvastatinCytochrome P450 2C9enzyme
DB01095FluvastatinCytochrome P450 3A4enzyme
DB01095FluvastatinCytochrome P450 2C8enzyme
DB01095FluvastatinCytochrome P450 2D6enzyme
DB01095FluvastatinCytochrome P450 2C19enzyme
DB01095FluvastatinCytochrome P450 1A1enzyme
DB01095FluvastatinSolute carrier organic anion transporter family member 1B1transporter
DB01095FluvastatinSolute carrier organic anion transporter family member 1B3transporter
DB01095FluvastatinSolute carrier organic anion transporter family member 2B1transporter
DB01095FluvastatinSolute carrier family 15 member 1transporter
DB01095FluvastatinCytochrome P450 3A5enzyme
DB01095FluvastatinUDP-glucuronosyltransferase 1-1enzyme
DB01095FluvastatinUDP-glucuronosyltransferase 1-3enzyme
DB01095FluvastatinUDP-glucuronosyltransferase 2B7enzyme
DB01095FluvastatinCanalicular multispecific organic anion transporter 1transporter
DB01095FluvastatinCytochrome P450 2B6enzyme
DB01097LeflunomideDihydroorotate dehydrogenase (quinone), mitochondrialtarget
DB01097LeflunomideCytochrome P450 1A2enzyme
DB01097LeflunomideCytochrome P450 2C9enzyme
DB01097LeflunomideAryl hydrocarbon receptortarget
DB01097LeflunomideProtein-tyrosine kinase 2-betatarget
DB01097LeflunomideATP-binding cassette sub-family G member 2transporter
DB01098Rosuvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB01098RosuvastatinCytochrome P450 2C9enzyme
DB01098RosuvastatinMultidrug resistance-associated protein 4transporter
DB01098RosuvastatinMultidrug resistance-associated protein 1transporter
DB01098RosuvastatinCytochrome P450 2C19enzyme
DB01098RosuvastatinCytochrome P450 3A4enzyme
DB01098RosuvastatinCytochrome P450 3A5enzyme
DB01098RosuvastatinSolute carrier organic anion transporter family member 1A2transporter
DB01098RosuvastatinSolute carrier organic anion transporter family member 1B3transporter
DB01098RosuvastatinSolute carrier organic anion transporter family member 2B1transporter
DB01098RosuvastatinCystine/glutamate transportertransporter
DB01098RosuvastatinSolute carrier organic anion transporter family member 1B1transporter
DB01098RosuvastatinBile salt export pumptransporter
DB01098RosuvastatinATP-binding cassette sub-family G member 2transporter
DB01098RosuvastatinSerum albumincarrier
DB01098RosuvastatinCanalicular multispecific organic anion transporter 1transporter
DB01098RosuvastatinSolute carrier family 22 member 8transporter
DB01103QuinacrineDNAtarget
DB01103Quinacrine85/88 kDa calcium-independent phospholipase A2target
DB01103QuinacrineCytosolic phospholipase A2target
DB01103QuinacrineInactive phospholipase C-like protein 1target
DB01103QuinacrineHistamine N-methyltransferaseenzyme
DB01103QuinacrineSolute carrier family 22 member 2transporter
DB01103QuinacrineMultidrug resistance protein 1transporter
DB01103QuinacrineCytochrome P450 3A4enzyme
DB01103QuinacrineCytochrome P450 3A5enzyme
DB01108Trilostane3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB01108Trilostane3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2target
DB01108TrilostaneEstrogen receptor betatarget
DB01108TrilostaneEstrogen receptor alphatarget
DB01108TrilostaneCytochrome P450 3A4enzyme
DB01110MiconazoleCytochrome P450 2C9enzyme
DB01110MiconazoleCytochrome P450 2D6enzyme
DB01110MiconazoleCytochrome P450 3A4enzyme
DB01110MiconazoleMultidrug resistance protein 1transporter
DB01110MiconazoleLanosterol 14-alpha demethylasetarget
DB01110MiconazoleNitric oxide synthase, endothelialtarget
DB01110MiconazoleNitric oxide synthase, inducibletarget
DB01110MiconazoleCalcium-activated potassium channel subunit alpha-1target
DB01110MiconazoleCalcium-activated potassium channel subunit beta-1target
DB01110MiconazoleCalcium-activated potassium channel subunit beta-2target
DB01110MiconazoleCalcium-activated potassium channel subunit beta-3target
DB01110MiconazoleCalcium-activated potassium channel subunit beta-4target
DB01110MiconazoleIntermediate conductance calcium-activated potassium channel protein 4target
DB01110MiconazoleSmall conductance calcium-activated potassium channel protein 1target
DB01110MiconazoleSmall conductance calcium-activated potassium channel protein 2target
DB01110MiconazoleSmall conductance calcium-activated potassium channel protein 3target
DB01110MiconazolePotassium voltage-gated channel subfamily H member 2target
DB01110MiconazolePotassium voltage-gated channel subfamily H member 6target
DB01110MiconazolePotassium voltage-gated channel subfamily H member 7target
DB01110MiconazoleCytochrome P450 11B1, mitochondrialenzyme
DB01110MiconazoleCytochrome P450 2A6enzyme
DB01110MiconazoleCytochrome P450 2B6enzyme
DB01110MiconazoleCytochrome P450 2C19enzyme
DB01110MiconazoleCytochrome P450 2E1enzyme
DB01110MiconazoleNuclear receptor subfamily 1 group I member 2target
DB01110MiconazoleLanosterol 14-alpha demethylaseenzyme
DB01110MiconazoleCytochrome P450 19A1enzyme
DB01113PapaverinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB01113PapaverinecAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
DB01117AtovaquoneDihydroorotate dehydrogenase (quinone), mitochondrialtarget
DB01117AtovaquoneDihydroorotate dehydrogenase (quinone), mitochondrialtarget
DB01117AtovaquoneCytochrome btarget
DB01117AtovaquoneCytochrome P450 2C9enzyme
DB01117AtovaquoneCytochrome P450 3A4enzyme
DB01117AtovaquoneMultidrug resistance protein 1transporter
DB01118AmiodaroneBeta-1 adrenergic receptortarget
DB01118AmiodaronePotassium voltage-gated channel subfamily H member 2target
DB01118AmiodaroneCytochrome P450 2C8enzyme
DB01118AmiodaroneCytochrome P450 2C9enzyme
DB01118AmiodaroneCytochrome P450 2D6enzyme
DB01118AmiodaroneVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01118AmiodaroneVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB01118AmiodaroneCytochrome P450 3A4enzyme
DB01118AmiodaroneCytochrome P450 1A2enzyme
DB01118AmiodaroneCytochrome P450 3A5enzyme
DB01118AmiodaroneCytochrome P450 3A7enzyme
DB01118AmiodaroneCytochrome P450 1A1enzyme
DB01118AmiodaroneMultidrug resistance protein 1transporter
DB01118AmiodaroneCytochrome P450 2C19enzyme
DB01118AmiodaroneCytochrome P450 2A6enzyme
DB01118AmiodaroneThyroid hormone receptor alphatarget
DB01118AmiodaroneThyroid hormone receptor betatarget
DB01118AmiodaronePeroxisome proliferator-activated receptor gammatarget
DB01118AmiodaroneBile salt export pumptransporter
DB01118AmiodaroneSolute carrier family 22 member 2transporter
DB01122AmbenoniumAcetylcholinesterasetarget
DB01122AmbenoniumCholinesteraseenzyme
DB01126Dutasteride3-oxo-5-alpha-steroid 4-dehydrogenase 1target
DB01126Dutasteride3-oxo-5-alpha-steroid 4-dehydrogenase 2target
DB01126DutasterideCytochrome P450 3A4enzyme
DB01127EconazoleCytochrome P450 19A1enzyme
DB01127EconazoleCytochrome P450 2E1enzyme
DB01127EconazoleCytochrome P450 3A4enzyme
DB01127EconazoleLanosterol 14-alpha demethylasetarget
DB01127EconazoleNuclear receptor subfamily 1 group I member 2target
DB01129RabeprazolePotassium-transporting ATPase alpha chain 1target
DB01129RabeprazoleCytochrome P450 3A4enzyme
DB01129RabeprazoleCytochrome P450 2C19enzyme
DB01129RabeprazoleATP-binding cassette sub-family G member 2transporter
DB01129RabeprazoleCytochrome P450 1A1enzyme
DB01129RabeprazoleCytochrome P450 1A2enzyme
DB01129RabeprazoleCytochrome P450 2C9enzyme
DB01129RabeprazoleCytochrome P450 2D6enzyme
DB01129RabeprazoleCytochrome P450 2C8enzyme
DB01137LevofloxacinDNA gyrase subunit Atarget
DB01137LevofloxacinDNA topoisomerase 4 subunit Atarget
DB01137LevofloxacinDNA topoisomerase 2-alphatarget
DB01137LevofloxacinCytochrome P450 1A2enzyme
DB01137LevofloxacinSolute carrier family 22 member 2transporter
DB01137LevofloxacinMultidrug resistance protein 1transporter
DB01137LevofloxacinSolute carrier family 22 member 4transporter
DB01137LevofloxacinSolute carrier family 22 member 6transporter
DB01137LevofloxacinCytochrome P450 3A4enzyme
DB01137LevofloxacinMultidrug and toxin extrusion protein 1transporter
DB01137LevofloxacinMultidrug and toxin extrusion protein 2transporter
DB01144DiclofenamideCarbonic anhydrase 1target
DB01144DiclofenamideCarbonic anhydrase 4target
DB01144DiclofenamideCarbonic anhydrase 2target
DB01144DiclofenamideCarbonic anhydrase 7target
DB01144DiclofenamideCarbonic anhydrase 3target
DB01151DesipramineMuscarinic acetylcholine receptor M1target
DB01151DesipramineSodium-dependent noradrenaline transportertarget
DB01151DesipramineBeta-2 adrenergic receptortarget
DB01151DesipramineMuscarinic acetylcholine receptor M2target
DB01151DesipramineSodium-dependent serotonin transportertarget
DB01151DesipramineHistamine H1 receptortarget
DB01151DesipramineBeta-1 adrenergic receptortarget
DB01151DesipramineCytochrome P450 2D6enzyme
DB01151DesipramineMuscarinic acetylcholine receptor M3target
DB01151DesipramineMuscarinic acetylcholine receptor M4target
DB01151DesipramineMuscarinic acetylcholine receptor M5target
DB01151DesipramineAlpha-1 adrenergic receptorstarget
DB01151Desipramine5-hydroxytryptamine receptor 2Atarget
DB01151DesipramineAlpha-1-acid glycoprotein 1carrier
DB01151DesipramineCytochrome P450 2B6enzyme
DB01151DesipramineCytochrome P450 3A4enzyme
DB01151DesipramineSolute carrier family 22 member 2transporter
DB01151DesipramineSolute carrier family 22 member 1transporter
DB01151DesipramineSolute carrier family 22 member 3transporter
DB01151DesipramineSolute carrier family 22 member 5transporter
DB01151DesipramineMultidrug resistance protein 1transporter
DB01151DesipramineSolute carrier family 22 member 4transporter
DB01151DesipramineCytochrome P450 1A2enzyme
DB01151DesipramineCytochrome P450 2A6enzyme
DB01151DesipramineCytochrome P450 2C18enzyme
DB01151DesipramineCytochrome P450 2C19enzyme
DB01151DesipramineCytochrome P450 2E1enzyme
DB01151DesipramineSphingomyelin phosphodiesterasetarget
DB01151Desipramine5-hydroxytryptamine receptor 1Atarget
DB01151Desipramine5-hydroxytryptamine receptor 2Ctarget
DB01151DesipramineD(2) dopamine receptortarget
DB01151DesipramineAlpha-2 adrenergic receptorstarget
DB01155GemifloxacinDNA gyrase subunit Atarget
DB01155GemifloxacinDNA topoisomerase 4 subunit Atarget
DB01155GemifloxacinCytochrome P450 1A2enzyme
DB01156BupropionSodium-dependent dopamine transportertarget
DB01156BupropionSodium-dependent noradrenaline transportertarget
DB01156BupropionCytochrome P450 2B6enzyme
DB01156BupropionCytochrome P450 2D6enzyme
DB01156BupropionAlpha-1-acid glycoprotein 1carrier
DB01156BupropionNeuronal acetylcholine receptor subunit alpha-3target
DB01156BupropionCytochrome P450 2A6enzyme
DB01156BupropionCytochrome P450 2C8enzyme
DB01156BupropionCytochrome P450 2C9enzyme
DB01156BupropionCytochrome P450 2E1enzyme
DB01156BupropionCytochrome P450 3A4enzyme
DB01156BupropionSolute carrier family 22 member 2transporter
DB01157TrimetrexateDihydrofolate reductasetarget
DB01165OfloxacinDNA gyrase subunit Atarget
DB01165OfloxacinDNA topoisomerase 4 subunit Atarget
DB01165OfloxacinDNA topoisomerase 2-alphatarget
DB01165OfloxacinCytochrome P450 1A2enzyme
DB01165OfloxacinSolute carrier family 22 member 5transporter
DB01165OfloxacinMultidrug resistance-associated protein 1transporter
DB01165OfloxacinSolute carrier family 22 member 6transporter
DB01165OfloxacinCanalicular multispecific organic anion transporter 1transporter
DB01165OfloxacinSolute carrier family 22 member 4transporter
DB01165OfloxacinBile salt export pumptransporter
DB01166CilostazolcGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB01166CilostazolCytochrome P450 2C19enzyme
DB01166CilostazolCytochrome P450 3A4enzyme
DB01166CilostazolCytochrome P450 3A5enzyme
DB01166CilostazolCytochrome P450 3A7enzyme
DB01166CilostazolCytochrome P450 1A2enzyme
DB01166CilostazolCytochrome P450 2D6enzyme
DB01167ItraconazoleLanosterol 14-alpha demethylasetarget
DB01167ItraconazoleLanosterol 14-alpha demethylasetarget
DB01167ItraconazoleCytochrome P450 3A4enzyme
DB01167ItraconazoleCytochrome P450 2D6enzyme
DB01167ItraconazoleCytochrome P450 3A5enzyme
DB01167ItraconazoleCytochrome P450 3A7enzyme
DB01167ItraconazoleCytochrome P450 2B6enzyme
DB01167ItraconazoleMultidrug resistance protein 1transporter
DB01167ItraconazoleCytochrome P450 1A1enzyme
DB01167ItraconazoleCytochrome P450 2E1enzyme
DB01167ItraconazoleSolute carrier organic anion transporter family member 2B1transporter
DB01171MoclobemideAmine oxidase [flavin-containing] Atarget
DB01171MoclobemideCytochrome P450 2C19enzyme
DB01171MoclobemideCytochrome P450 2D6enzyme
DB01171MoclobemideAmine oxidase [flavin-containing] Aenzyme
DB01171MoclobemideAmine oxidase [flavin-containing] Benzyme
DB01171MoclobemideCytochrome P450 2C9enzyme
DB01171MoclobemideMonoamine oxidasetarget
DB01171MoclobemideAmine oxidase [flavin-containing] Btarget
DB01172Kanamycin30S ribosomal protein S12target
DB01172Kanamycin16S rRNAtarget
DB01172KanamycinAminoglycoside 2'-N-acetyltransferaseenzyme
DB01172KanamycinKanamycin nucleotidyltransferaseenzyme
DB01172KanamycinAminoglycoside 3'-phosphotransferaseenzyme
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 1target
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 2Dtarget
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 3Btarget
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 3Atarget
DB01173OrphenadrineHistamine H1 receptortarget
DB01173OrphenadrineCytochrome P450 2B6enzyme
DB01173OrphenadrineCytochrome P450 2E1enzyme
DB01173OrphenadrineCytochrome P450 3A4enzyme
DB01173OrphenadrineSodium-dependent noradrenaline transportertarget
DB01173OrphenadrineSodium channel protein type 10 subunit alphatarget
DB01173OrphenadrineCytochrome P450 1A2enzyme
DB01177IdarubicinDNA topoisomerase 2-alphatarget
DB01177IdarubicinDNAtarget
DB01177IdarubicinMultidrug resistance-associated protein 1transporter
DB01177IdarubicinCytochrome P450 2C9enzyme
DB01177IdarubicinCytochrome P450 2D6enzyme
DB01190Clindamycin50S ribosomal protein L10target
DB01190ClindamycinCytochrome P450 3A4enzyme
DB01190Clindamycin23S rRNAtarget
DB01194BrinzolamideCarbonic anhydrase 1target
DB01194BrinzolamideCarbonic anhydrase 2target
DB01194BrinzolamideCytochrome P450 3A4enzyme
DB01194BrinzolamideCarbonic anhydrase 5A, mitochondrialtarget
DB01194BrinzolamideCarbonic anhydrase 4target
DB01194BrinzolamideCarbonic anhydrase 3target
DB01197CaptoprilAngiotensin-converting enzymetarget
DB01197CaptoprilCytochrome P450 2D6enzyme
DB01197CaptoprilSerum albumincarrier
DB01197Captopril72 kDa type IV collagenasetarget
DB01197CaptoprilMatrix metalloproteinase-9target
DB01197CaptoprilMultidrug resistance protein 1transporter
DB01197CaptoprilSolute carrier family 15 member 1transporter
DB01197CaptoprilSolute carrier family 22 member 6transporter
DB01197CaptoprilLeukotriene A-4 hydrolasetarget
DB01197CaptoprilB1 bradykinin receptortarget
DB01204MitoxantroneDNA topoisomerase 2-alphatarget
DB01204MitoxantroneCytochrome P450 2E1enzyme
DB01204MitoxantroneMultidrug resistance protein 1transporter
DB01204MitoxantroneMultidrug resistance-associated protein 1transporter
DB01204MitoxantroneATP-binding cassette sub-family G member 2transporter
DB01204MitoxantroneDNAtarget
DB01204MitoxantroneCytochrome P450 1B1enzyme
DB01204MitoxantroneCytochrome P450 3A4enzyme
DB01207RidogrelThromboxane-A synthasetarget
DB01207RidogrelThromboxane A2 receptortarget
DB01208SparfloxacinDNA gyrase subunit Atarget
DB01208SparfloxacinDNA topoisomerase 4 subunit Atarget
DB01208SparfloxacinDNA topoisomerase 2-alphatarget
DB01208SparfloxacinSolute carrier family 22 member 5transporter
DB01208SparfloxacinCanalicular multispecific organic anion transporter 1transporter
DB01208SparfloxacinMultidrug resistance protein 1transporter
DB01208SparfloxacinCytochrome P450 1A2enzyme
DB01211Clarithromycin50S ribosomal protein L10target
DB01211ClarithromycinCytochrome P450 3A4enzyme
DB01211ClarithromycinCytochrome P450 2C19enzyme
DB01211ClarithromycinCytochrome P450 3A5enzyme
DB01211ClarithromycinCytochrome P450 3A7enzyme
DB01211ClarithromycinMultidrug resistance protein 1transporter
DB01211ClarithromycinSolute carrier family 22 member 7transporter
DB01211ClarithromycinPotassium voltage-gated channel subfamily H member 2target
DB01211ClarithromycinSolute carrier organic anion transporter family member 1B1target
DB01211ClarithromycinSolute carrier organic anion transporter family member 1B3target
DB01211ClarithromycinBile salt export pumptransporter
DB01216Finasteride3-oxo-5-alpha-steroid 4-dehydrogenase 1target
DB01216FinasterideCytochrome P450 3A4enzyme
DB01216Finasteride3-oxo-5-alpha-steroid 4-dehydrogenase 2target
DB01216Finasteride3-oxo-5-beta-steroid 4-dehydrogenasetarget
DB01216FinasterideCytochrome P450 3A5enzyme
DB01216FinasterideCytochrome P450 3A7enzyme
DB01217AnastrozoleCytochrome P450 19A1target
DB01217AnastrozoleCytochrome P450 19A1enzyme
DB01217AnastrozoleCytochrome P450 1A2enzyme
DB01217AnastrozoleCytochrome P450 2C9enzyme
DB01217AnastrozoleCytochrome P450 3A4enzyme
DB01220RifaximinDNA-directed RNA polymerase subunit betatarget
DB01220RifaximinNuclear receptor subfamily 1 group I member 2target
DB01220RifaximinCytochrome P450 3A4enzyme
DB01220RifaximinCytochrome P450 2C19enzyme
DB01220RifaximinCytochrome P450 2C8enzyme
DB01220RifaximinCytochrome P450 2D6enzyme
DB01223AminophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB01223AminophyllineAdenosine receptor A3target
DB01223AminophyllineAdenosine receptor A1target
DB01223AminophyllineCytochrome P450 1A2enzyme
DB01223AminophyllineCytochrome P450 2E1enzyme
DB01223AminophyllineCytochrome P450 3A4enzyme
DB01223AminophyllineHistone deacetylase 2target
DB01223AminophyllineCytochrome P450 2C19enzyme
DB01232SaquinavirHuman immunodeficiency virus type 1 proteasetarget
DB01232SaquinavirCytochrome P450 3A4enzyme
DB01232SaquinavirCytochrome P450 3A5enzyme
DB01232SaquinavirAlpha-1-acid glycoprotein 1carrier
DB01232SaquinavirSerum albumincarrier
DB01232SaquinavirCytochrome P450 3A7enzyme
DB01232SaquinavirMultidrug resistance protein 1transporter
DB01232SaquinavirSolute carrier family 22 member 1transporter
DB01232SaquinavirSolute carrier organic anion transporter family member 1A2transporter
DB01232SaquinavirATP-binding cassette sub-family G member 2transporter
DB01232SaquinavirSolute carrier organic anion transporter family member 1B1transporter
DB01232SaquinavirMultidrug resistance-associated protein 1transporter
DB01232SaquinavirCanalicular multispecific organic anion transporter 1transporter
DB01232SaquinavirCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB01232SaquinavirCytochrome P450 2C8enzyme
DB01232SaquinavirCytochrome P450 2D6enzyme
DB01232SaquinavirSolute carrier organic anion transporter family member 2B1transporter
DB01232SaquinavirBile salt export pumptransporter
DB01241GemfibrozilPeroxisome proliferator-activated receptor alphatarget
DB01241GemfibrozilCytochrome P450 2C9enzyme
DB01241GemfibrozilCytochrome P450 2C8enzyme
DB01241GemfibrozilCytochrome P450 1A2enzyme
DB01241GemfibrozilCytochrome P450 2C19enzyme
DB01241GemfibrozilSolute carrier organic anion transporter family member 1B1transporter
DB01241GemfibrozilUDP-glucuronosyltransferase 1-1enzyme
DB01241GemfibrozilCytochrome P450 3A4enzyme
DB01241GemfibrozilUDP-glucuronosyltransferase 1-3enzyme
DB01247IsocarboxazidAmine oxidase [flavin-containing] Atarget
DB01247IsocarboxazidAmine oxidase [flavin-containing] Btarget
DB01254DasatinibTyrosine-protein kinase ABL1target
DB01254DasatinibAbelson tyrosine-protein kinase 2target
DB01254DasatinibProto-oncogene tyrosine-protein kinase Srctarget
DB01254DasatinibTyrosine-protein kinase Fyntarget
DB01254DasatinibTyrosine-protein kinase Lcktarget
DB01254DasatinibTyrosine-protein kinase Yestarget
DB01254DasatinibMast/stem cell growth factor receptor Kittarget
DB01254DasatinibPlatelet-derived growth factor receptor betatarget
DB01254DasatinibEphrin type-A receptor 2target
DB01254DasatinibSignal transducer and activator of transcription 5Btarget
DB01254DasatinibCytochrome P450 3A4enzyme
DB01254DasatinibMultidrug resistance protein 1transporter
DB01254DasatinibATP-binding cassette sub-family G member 2transporter
DB01254DasatinibCytochrome P450 1A1enzyme
DB01254DasatinibCytochrome P450 1A2enzyme
DB01254DasatinibCytochrome P450 1B1enzyme
DB01254DasatinibCytochrome P450 3A5enzyme
DB01254DasatinibDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB01254DasatinibTyrosine-protein kinase BTKtarget
DB01254DasatinibNuclear receptor subfamily 4 group A member 3target
DB01254DasatinibBreakpoint cluster region proteintarget
DB01254DasatinibTyrosine-protein kinase CSKtarget
DB01254DasatinibEphrin type-A receptor 5target
DB01254DasatinibEphrin type-B receptor 4target
DB01254DasatinibTyrosine-protein kinase Fgrtarget
DB01254DasatinibTyrosine-protein kinase FRKtarget
DB01254DasatinibHeat shock cognate 71 kDa proteintarget
DB01254DasatinibTyrosine-protein kinase Lyntarget
DB01254DasatinibMitogen-activated protein kinase kinase kinase MLTtarget
DB01254DasatinibMitogen-activated protein kinase 14target
DB01254DasatinibAmidophosphoribosyltransferasetarget
DB01259LapatinibEpidermal growth factor receptortarget
DB01259LapatinibReceptor tyrosine-protein kinase erbB-2target
DB01259LapatinibCytochrome P450 3A4enzyme
DB01259LapatinibCytochrome P450 2C8enzyme
DB01259LapatinibMultidrug resistance protein 1transporter
DB01259LapatinibAntigen peptide transporter 1transporter
DB01259LapatinibCytochrome P450 3A5enzyme
DB01259LapatinibCytochrome P450 2C19enzyme
DB01261SitagliptinDipeptidyl peptidase 4target
DB01261SitagliptinCytochrome P450 3A4enzyme
DB01261SitagliptinCytochrome P450 2C8enzyme
DB01261SitagliptinMultidrug resistance protein 1transporter
DB01261SitagliptinSolute carrier family 22 member 8transporter
DB01262DecitabineDNAtarget
DB01262DecitabineDNA (cytosine-5)-methyltransferase 1target
DB01262DecitabineDeoxycytidine kinaseenzyme
DB01263PosaconazoleCytochrome P450 3A4enzyme
DB01263PosaconazoleMultidrug resistance protein 1transporter
DB01263PosaconazoleLanosterol 14-alpha demethylasetarget
DB01264DarunavirHuman immunodeficiency virus type 1 proteasetarget
DB01264DarunavirCytochrome P450 3A4enzyme
DB01264DarunavirSolute carrier organic anion transporter family member 1B1transporter
DB01264DarunavirMultidrug resistance protein 1transporter
DB01265TelbivudineProtein Ptarget
DB01265TelbivudineDNAtarget
DB01283LumiracoxibProstaglandin G/H synthase 2target
DB01283LumiracoxibProstaglandin G/H synthase 1target
DB01283LumiracoxibCytochrome P450 2C9enzyme
DB01283LumiracoxibCytochrome P450 2C19enzyme
DB01283LumiracoxibUDP-glucuronosyltransferase 1-9enzyme
DB01283LumiracoxibCytochrome P450 1A2enzyme
DB01319FosamprenavirHuman immunodeficiency virus type 1 proteasetarget
DB01319FosamprenavirCytochrome P450 3A4enzyme
DB01340CilazaprilAngiotensin-converting enzymetarget
DB01340CilazaprilMultidrug resistance protein 1transporter
DB01340CilazaprilSolute carrier family 15 member 1transporter
DB01340CilazaprilSolute carrier family 15 member 2transporter
DB01348SpiraprilAngiotensin-converting enzymetarget
DB01348SpiraprilSolute carrier family 15 member 1transporter
DB01348SpiraprilSolute carrier family 15 member 2transporter
DB01367RasagilineApoptosis regulator Bcl-2target
DB01367RasagilineAmine oxidase [flavin-containing] Btarget
DB01367RasagilineCytochrome P450 1A2enzyme
DB01388MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB01388MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit beta-1target
DB01388MibefradilCytochrome P450 3A4enzyme
DB01388MibefradilCytochrome P450 1A2enzyme
DB01388MibefradilCytochrome P450 2D6enzyme
DB01388MibefradilCytochrome P450 3A5enzyme
DB01388MibefradilCytochrome P450 3A7enzyme
DB01388MibefradilMultidrug resistance protein 1transporter
DB01388MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01388MibefradilVoltage-dependent L-type calcium channel subunit beta-2target
DB01388MibefradilVoltage-dependent L-type calcium channel subunit beta-3target
DB01388MibefradilVoltage-dependent L-type calcium channel subunit beta-4target
DB01388MibefradilCytochrome P450 11B1, mitochondrialenzyme
DB01388MibefradilCytochrome P450 11B2, mitochondrialenzyme
DB01388MibefradilCytochrome P450 1A1enzyme
DB01396DigitoxinSodium/potassium-transporting ATPase subunit alpha-1target
DB01396DigitoxinSerum albumincarrier
DB01396DigitoxinCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB01396DigitoxinCytochrome P450 3A4enzyme
DB01396DigitoxinSolute carrier organic anion transporter family member 1A2transporter
DB01396DigitoxinSolute carrier organic anion transporter family member 4C1transporter
DB01396DigitoxinMultidrug resistance protein 1transporter
DB01397Magnesium salicylateSerum albumincarrier
DB01397Magnesium salicylateProstaglandin G/H synthase 1target
DB01397Magnesium salicylateProstaglandin G/H synthase 2target
DB01400NeostigmineAcetylcholinesterasetarget
DB01400NeostigmineCholinesteraseenzyme
DB01405TemafloxacinDNA gyrase subunit Atarget
DB01405TemafloxacinDNA topoisomerase 4 subunit Atarget
DB01405TemafloxacinCytochrome P450 1A2enzyme
DB01427AmrinonecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB01427AmrinoneTumor necrosis factortarget
DB01427AmrinonecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB01427AmrinonecAMP-specific 3',5'-cyclic phosphodiesterase 3target
DB01597CilastatinDipeptidase 1target
DB01597CilastatinSolute carrier family 22 member 6transporter
DB01597CilastatinSolute carrier family 22 member 8transporter
DB01601LopinavirHuman immunodeficiency virus type 1 proteasetarget
DB01601LopinavirCytochrome P450 3A4enzyme
DB01601LopinavirCytochrome P450 2D6enzyme
DB01601LopinavirCytochrome P450 2C19enzyme
DB01601LopinavirMultidrug resistance protein 1transporter
DB01601LopinavirCytochrome P450 2B6enzyme
DB01601LopinavirCytochrome P450 2C9enzyme
DB01601LopinavirCytochrome P450 2C8enzyme
DB01601LopinavirCYP3Aenzyme
DB01601LopinavirSolute carrier organic anion transporter family member 1B1transporter
DB01601LopinavirSolute carrier organic anion transporter family member 1B3transporter
DB01601LopinavirBile salt export pumptransporter
DB01606TazobactamBeta-lactamase SHV-1target
DB01606TazobactamBeta-lactamase TEMtarget
DB01606TazobactamSolute carrier family 22 member 6transporter
DB01606TazobactamSolute carrier family 22 member 8transporter
DB01611HydroxychloroquineDNAtarget
DB01611HydroxychloroquineToll-like receptor 7target
DB01611HydroxychloroquineToll-like receptor 9target
DB01611HydroxychloroquineCytochrome P450 2D6enzyme
DB01611HydroxychloroquineMultidrug resistance protein 1transporter
DB01626PargylineAmine oxidase [flavin-containing] Btarget
DB01626PargylineAmine oxidase [flavin-containing] Atarget
DB01627Lincomycin50S ribosomal protein L10target
DB01628EtoricoxibProstaglandin G/H synthase 2target
DB01628EtoricoxibCytochrome P450 3A4enzyme
DB01628EtoricoxibCytochrome P450 2C9enzyme
DB01628EtoricoxibCytochrome P450 2D6enzyme
DB01628EtoricoxibCytochrome P450 1A2enzyme
DB01628EtoricoxibCytochrome P450 2C19enzyme
DB01628EtoricoxibCytochrome P450 2E1enzyme
DB01645GenisteinEstrogen receptor betatarget
DB01645GenisteinDNA topoisomerase 2-alphatarget
DB01645GenisteinProtein-tyrosine kinase 2-betatarget
DB01645GenisteinMultidrug resistance protein 1transporter
DB01645GenisteinMultidrug resistance-associated protein 1transporter
DB01645GenisteinATP-binding cassette sub-family G member 2transporter
DB01645GenisteinCytochrome P450 1A2enzyme
DB01645GenisteinNuclear receptor coactivator 1target
DB01645GenisteinEstrogen receptor alphatarget
DB01645GenisteinNuclear receptor coactivator 2target
DB01645GenisteinTransthyretincarrier
DB01645GenisteinSteroid hormone receptor ERR2target
DB01645GenisteinSteroid hormone receptor ERR1target
DB01645GenisteinNuclear receptor subfamily 1 group I member 2target
DB01645GenisteinRAC-alpha serine/threonine-protein kinasetarget
DB01645GenisteinG-protein coupled estrogen receptor 1target
DB01645GenisteinCytochrome P450 1B1target
DB01645GenisteinSex hormone-binding globulintarget
DB01645GenisteinCytochrome P450 1A1enzyme
DB01645GenisteinSolute carrier organic anion transporter family member 1B1transporter
DB01645GenisteinSolute carrier organic anion transporter family member 2B1transporter
DB01645GenisteinCytochrome P450 2C8enzyme
DB01645GenisteinCytochrome P450 2C9enzyme
DB01645GenisteinCytochrome P450 3A1enzyme
DB01645GenisteinCytochrome P450 3A2enzyme
DB01645GenisteinCytochrome P450 3A4enzyme
DB01683ChymostatinPeptide amidasetarget
DB01686N,N-dimethylarginineNitric oxide synthase, inducibletarget
DB01686N,N-dimethylarginineNitric oxide synthase, endothelialtarget
DB01791PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB01791PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB01791PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
DB01791PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB01816CastanospermineGlucan 1,3-beta-glucosidasetarget
DB019337-Hydroxystaurosporine3-phosphoinositide-dependent protein kinase 1target
DB01954RolipramcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB01954RolipramcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB02010StaurosporineTyrosine-protein kinase Lcktarget
DB02010StaurosporineSerine/threonine-protein kinase pim-1target
DB02010StaurosporineTyrosine-protein kinase ITK/TSKtarget
DB02010StaurosporineTyrosine-protein kinase SYKtarget
DB02010StaurosporineMAP kinase-activated protein kinase 2target
DB02010StaurosporineGlycogen synthase kinase-3 betatarget
DB02010StaurosporineTyrosine-protein kinase CSKtarget
DB02010StaurosporineCyclin-dependent kinase 2target
DB02010StaurosporinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
DB02010Staurosporine3-phosphoinositide-dependent protein kinase 1target
DB02010StaurosporineProtein kinase C theta typetarget
DB02010StaurosporineTyrosine-protein kinase ZAP-70target
DB02010StaurosporineMultidrug resistance protein 1transporter
DB02010StaurosporineMuscarinic acetylcholine receptor M1target
DB02020AlrestatinAldose reductasetarget
DB02044N-(3-(Aminomethyl)Benzyl)AcetamidineNitric oxide synthase, endothelialtarget
DB02044N-(3-(Aminomethyl)Benzyl)AcetamidineNitric oxide synthase, inducibletarget
DB02044N-(3-(Aminomethyl)Benzyl)AcetamidineNitric oxide synthase, braintarget
DB02054GabaculineOrnithine aminotransferase, mitochondrialtarget
DB02054GabaculineGlutamate-1-semialdehyde 2,1-aminomutasetarget
DB02079Aminooxyacetic acidSerine--pyruvate aminotransferasetarget
DB021053,5-DinitrocatecholCatechol O-methyltransferasetarget
DB02115DaidzinAldehyde dehydrogenase, mitochondrialtarget
DB02115DaidzinATP-binding cassette sub-family G member 2transporter
DB02116OlomoucineCyclin-dependent kinase 2target
DB02116OlomoucineCyclin-dependent kinase 5target
DB02116OlomoucineCyclin-dependent kinase 1target
DB02116OlomoucineMitogen-activated protein kinase 1target
DB02152K-252aHepatocyte growth factor receptortarget
DB02152K-252aDual specificity mitogen-activated protein kinase kinase 1target
DB022077-NitroindazoleNitric oxide synthase, endothelialtarget
DB022077-NitroindazoleNitric oxide synthase, inducibletarget
DB02255GM6001Lethal factortarget
DB02255GM6001Disintegrin and metalloproteinase domain-containing protein 28target
DB02255GM6001Aggrecan core proteintarget
DB022825'-Deoxy-5'-MethylthioadenosineModification methylase RsrItarget
DB022825'-Deoxy-5'-MethylthioadenosineS-methyl-5'-thioadenosine phosphorylasetarget
DB023651,10-PhenanthrolineMethyl-accepting chemotaxis protein IItarget
DB023651,10-PhenanthrolineMetallo-beta-lactamase L1target
DB02383TolrestatAldose reductasetarget
DB02383TolrestatAlcohol dehydrogenase [NADP(+)]target
DB02383TolrestatAldo-keto reductase family 1 member B10target
DB02424GeldanamycinHeat shock protein HSP 90-alphatarget
DB02424GeldanamycinHeat shock protein HSP 90-betatarget
DB02424GeldanamycinEndoplasmintarget
DB02430Trehalose-6-PhosphateHTH-type transcriptional regulator TreRtarget
DB02546VorinostatHistone deacetylase 1target
DB02546VorinostatHistone deacetylase 2target
DB02546VorinostatHistone deacetylase 3target
DB02546VorinostatHistone deacetylase 6target
DB02546VorinostatHistone deacetylase 8target
DB02546VorinostatAcetoin utilization proteintarget
DB02557PhosphoramidonNeprilysintarget
DB02557PhosphoramidonKell blood group glycoproteintarget
DB02656LY-294002Serine/threonine-protein kinase pim-1target
DB02656LY-294002Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
DB02703Fusidic AcidChloramphenicol acetyltransferase 3target
DB02703Fusidic AcidChloramphenicol acetyltransferasetarget
DB02703Fusidic AcidBile salt export pumptransporter
DB02703Fusidic AcidCanalicular multispecific organic anion transporter 1transporter
DB02703Fusidic AcidElongation factor Gtarget
DB02703Fusidic AcidCytochrome P450 2D6enzyme
DB02703Fusidic AcidCytochrome P450 3A4enzyme
DB02703Fusidic AcidUDP-glucuronosyltransferase 1-1enzyme
DB02703Fusidic AcidATP-binding cassette sub-family G member 2transporter
DB02703Fusidic AcidSolute carrier organic anion transporter family member 1B1transporter
DB02709ResveratrolTransthyretincarrier
DB02709ResveratrolRibosyldihydronicotinamide dehydrogenase [quinone]target
DB02709ResveratrolProstaglandin G/H synthase 1target
DB02709ResveratrolCasein kinase II subunit alphatarget
DB02709ResveratrolProstaglandin G/H synthase 2target
DB02709ResveratrolCytochrome P450 1A1enzyme
DB02709ResveratrolCytochrome P450 3A4enzyme
DB02709ResveratrolCytochrome P450 1A2enzyme
DB02709ResveratrolCytochrome P450 1B1enzyme
DB02709ResveratrolArachidonate 15-lipoxygenasetarget
DB02709ResveratrolArachidonate 5-lipoxygenasetarget
DB02709ResveratrolAryl hydrocarbon receptortarget
DB02709ResveratrolPhosphatidylinositol 4-kinase type 2-betatarget
DB02709ResveratrolIntegrin alpha-5target
DB02709ResveratrolIntegrin beta-3target
DB02709ResveratrolSerum albumincarrier
DB02709ResveratrolAmyloid beta A4 proteintarget
DB02709ResveratrolAlpha-synucleintarget
DB02709ResveratrolEstrogen receptor alphatarget
DB02709ResveratrolMelatonin receptor type 1Atarget
DB02709ResveratrolMelatonin receptor type 1Btarget
DB02709ResveratrolC-type lectin domain family 14 member Atarget
DB02709ResveratrolNuclear receptor subfamily 1 group I member 2target
DB02709ResveratrolNuclear receptor subfamily 1 group I member 3target
DB02709ResveratrolSolute carrier family 2, facilitated glucose transporter member 1target
DB02709ResveratrolCarbonyl reductase [NADPH] 1target
DB02709ResveratrolPeroxisome proliferator-activated receptor alphatarget
DB02709ResveratrolPeroxisome proliferator-activated receptor gammatarget
DB02709ResveratrolRAC-alpha serine/threonine-protein kinasetarget
DB02709ResveratrolFar upstream element-binding protein 2target
DB02709ResveratrolTyrosine--tRNA ligase, cytoplasmictarget
DB02742KifunensineAlpha-mannosidase 2target
DB02742KifunensineEndoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidasetarget
DB02742KifunensineMannosyl-oligosaccharide alpha-1,2-mannosidasetarget
DB02757PyrazoleAlcohol dehydrogenase 1Ctarget
DB02757PyrazoleEstrogen receptor alphatarget
DB02757PyrazoleEstrogen receptor betatarget
DB02823Phosphonoacetic AcidAlkaline phosphatasetarget
DB02855N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-ProlineCathepsin Btarget
DB02860Calyculin ASerine/threonine-protein phosphatase PP1-gamma catalytic subunittarget
DB02967N-EthylmaleimideGalectin-10target
DB03052DazoxibenThromboxane-A synthasetarget
DB030733-MethoxybenzamidePoly [ADP-ribose] polymerase 1target
DB03127BenzamidineUrokinase-type plasminogen activatortarget
DB03127BenzamidineTrypsin-1target
DB03127BenzamidineCasein kinase II subunit alphatarget
DB03127BenzamidineKallikrein-6target
DB03127BenzamidineTrypsin-2target
DB03127BenzamidineTrypsin-3target
DB03127BenzamidineCopper transport protein ATOX1target
DB03127BenzamidineEnoyl-CoA delta isomerase 1, mitochondrialtarget
DB03127BenzamidineTrypsintarget
DB03127BenzamidineSuppressor of tumorigenicity 14 proteintarget
DB03127BenzamidineKallikrein-1target
DB03206DuvoglustatCyclomaltodextrin glucanotransferasetarget
DB03206DuvoglustatBeta-glucosidase Atarget
DB03206DuvoglustatEndoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidasetarget
DB03206DuvoglustatMannosyl-oligosaccharide alpha-1,2-mannosidasetarget
DB03206DuvoglustatXylose isomerasetarget
DB03366ImidazoleMonomeric sarcosine oxidasetarget
DB03366ImidazoleNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferasetarget
DB03366ImidazoleMyoglobintarget
DB03366ImidazoleNitric oxide synthase, inducibletarget
DB03366ImidazoleAdenylate kinase 2, mitochondrialtarget
DB03366ImidazoleSerine/threonine-protein kinase pim-1target
DB03366ImidazoleIsopentenyl-diphosphate Delta-isomerasetarget
DB03366ImidazoleAlpha,alpha-trehalose-phosphate synthase [UDP-forming]target
DB03366ImidazoleLeukotriene A-4 hydrolasetarget
DB03366ImidazoleGephyrintarget
DB03366ImidazoleAcyl carrier proteintarget
DB03366ImidazoleSensor protein FixLtarget
DB03366ImidazoleCytochrome ctarget
DB03366ImidazoleCircadian clock protein KaiBtarget
DB03366ImidazoleHistidinol dehydrogenasetarget
DB03366ImidazoleAcyl-CoA thioesterase Itarget
DB03366ImidazoleA/G-specific adenine glycosylasetarget
DB03366ImidazoleYopE regulatortarget
DB03366ImidazoleUnconventional myosin-Ietarget
DB03366ImidazoleMeiotic recombination protein DMC1/LIM15 homologtarget
DB03366ImidazoleGuanine deaminasetarget
DB03366ImidazoleEndo-1,4-beta-xylanase Atarget
DB03366ImidazoleBacterial hemoglobintarget
DB03366ImidazoleMolybdenum cofactor biosynthesis protein Btarget
DB03366ImidazoleUracil-DNA glycosylase inhibitortarget
DB03366ImidazoleRecombination protein RecRtarget
DB03395EnalkirenRenintarget
DB03424UbenimexBacterial leucyl aminopeptidasetarget
DB03424UbenimexLeukotriene A-4 hydrolasetarget
DB03424UbenimexSolute carrier family 15 member 1transporter
DB03424UbenimexSolute carrier family 15 member 2transporter
DB03459Sparfosic acidAspartate carbamoyltransferase catalytic chaintarget
DB03459Sparfosic acidCAD proteintarget
DB03496AlvocidibGlycogen phosphorylase, muscle formtarget
DB03496AlvocidibCyclin-dependent kinase 7target
DB03496AlvocidibCyclin-dependent kinase 5target
DB03496AlvocidibCyclin-dependent kinase 9target
DB03496AlvocidibCyclin-dependent kinase 1target
DB03496AlvocidibCyclin-dependent kinase 6target
DB03496AlvocidibEpidermal growth factor receptortarget
DB03496AlvocidibCyclin-dependent kinase 4target
DB03496AlvocidibCyclin-dependent kinase 8target
DB03496AlvocidibCyclin-dependent kinase 2target
DB03496AlvocidibATP-binding cassette sub-family G member 2transporter
DB03496AlvocidibGlycogen phosphorylase, brain formtarget
DB03496AlvocidibGlycogen phosphorylase, liver formtarget
DB03496AlvocidibUDP-glucuronosyltransferase 1-1enzyme
DB035092-(4-Chlorophenyl)-5-QuinoxalinecarboxamidePoly [ADP-ribose] polymerase 1target
DB03516EniluracilDihydropyrimidine dehydrogenase [NADP(+)]target
DB03516EniluracilAldehyde oxidasetarget
DB03516EniluracilXanthine dehydrogenase/oxidasetarget
DB03575PhencyclidineGlutamate receptor ionotropic, NMDA 3Atarget
DB03575PhencyclidineSigma non-opioid intracellular receptor 1target
DB03575PhencyclidineCytochrome P450 2B6enzyme
DB03651Picric acidPentaerythritol tetranitrate reductasetarget
DB03758RadicicolHeat shock protein HSP 90-betatarget
DB03758RadicicolEndoplasmintarget
DB03758RadicicolDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrialtarget
DB03758Radicicol[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrialtarget
DB03758RadicicolVirulence sensor histidine kinase PhoQtarget
DB03796Palmitic AcidRhodopsintarget
DB03796Palmitic AcidSerum albumincarrier
DB03796Palmitic AcidSEC14-like protein 2target
DB03796Palmitic AcidPalmitoyl-protein thioesterase 1target
DB03796Palmitic AcidMyelin P2 proteintarget
DB03796Palmitic AcidFatty acid-binding protein, adipocytecarrier
DB03796Palmitic AcidFatty acid-binding protein, epidermalcarrier
DB03796Palmitic AcidGlycodelintarget
DB03796Palmitic AcidFatty acid-binding protein, heartcarrier
DB03796Palmitic AcidHepatocyte nuclear factor 4-gammatarget
DB03796Palmitic AcidLipid binding proteintarget
DB03796Palmitic AcidCytochrome P450 2C8target
DB03796Palmitic AcidTrafficking protein particle complex subunit 3target
DB03796Palmitic AcidFatty acid-binding protein TM_1468target
DB03796Palmitic AcidFatty acid-binding protein, intestinalcarrier
DB03796Palmitic AcidAlpha-lactalbumintarget
DB03796Palmitic AcidPeroxisome proliferator-activated receptor alphatarget
DB03849CilomilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB03849CilomilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB03880BatimastatNeutrophil collagenasetarget
DB03880BatimastatMacrophage metalloelastasetarget
DB03880BatimastatMatrix metalloproteinase-16target
DB03880BatimastatDisintegrin and metalloproteinase domain-containing protein 28target
DB03880BatimastatA disintegrin and metalloproteinase with thrombospondin motifs 5target
DB039551-deoxymannojirimycinAlpha-mannosidase 2target
DB04132S-HexylglutathioneLactoylglutathione lyasetarget
DB04132S-HexylglutathioneGlutathione S-transferase Mu 4target
DB04132S-HexylglutathioneGlutathione S-transferase Ptarget
DB04132S-HexylglutathioneGlutathione S-transferasetarget
DB04132S-HexylglutathioneGlutathione S-transferase A1target
DB04132S-HexylglutathioneGlutathione S-transferase theta-2target
DB04132S-HexylglutathioneGlutathione S-transferase A1enzyme
DB04223NitroarginineNitric oxide synthase, endothelialtarget
DB04223NitroarginineNitric oxide synthase, braintarget
DB04267Dipicolinic Acid4-hydroxy-tetrahydrodipicolinate reductasetarget
DB04267Dipicolinic Acid4-hydroxy-tetrahydrodipicolinate reductasetarget
DB04299Maleic AcidAspartate aminotransferasetarget
DB04299Maleic AcidTrypanothione reductasetarget
DB04299Maleic AcidAspartate aminotransferasetarget
DB04299Maleic AcidAromatic-amino-acid aminotransferasetarget
DB04299Maleic AcidAspartate aminotransferase, cytoplasmictarget
DB044593,4-DichloroisocoumarinComplement factor Dtarget
DB04513N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideCalmodulintarget
DB04513N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideTroponin C, slow skeletal and cardiac musclestarget
DB04513N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideTroponin I, cardiac muscletarget
DB045282,4-DinitrophenolPentaerythritol tetranitrate reductasetarget
DB04539Glyphosate3-phosphoshikimate 1-carboxyvinyltransferasetarget
DB04539Glyphosate3-phosphoshikimate 1-carboxyvinyltransferasetarget
DB04539GlyphosateCytochrome P450 19A1target
DB04539GlyphosateSerum albumincarrier
DB04552Niflumic AcidPhospholipase A2target
DB04552Niflumic AcidChloride channel protein ClC-Katarget
DB04552Niflumic AcidMonocarboxylate transporter 2transporter
DB04552Niflumic AcidMonocarboxylate transporter 1transporter
DB04552Niflumic AcidProstaglandin G/H synthase 2target
DB04552Niflumic AcidProstaglandin G/H synthase 1target
DB04552Niflumic AcidCytosolic phospholipase A2target
DB04552Niflumic AcidUDP-glucuronosyltransferase 1-9target
DB04552Niflumic AcidUDP-glucuronosyltransferase 1-9enzyme
DB04576FleroxacinDNA topoisomerase 2-alphatarget
DB04576FleroxacinDNA gyrase subunit Atarget
DB04576FleroxacinDNA topoisomerase 4 subunit Atarget
DB04576FleroxacinCytochrome P450 1A2enzyme
DB046045-iodotubercidinCasein kinase I isoform gamma-2target
DB046045-iodotubercidinSerine/threonine-protein kinase haspintarget
DB046045-iodotubercidinMitogen-activated protein kinase 3target
DB04628AllosamidinChitinase Btarget
DB04628AllosamidinChitinase Atarget
DB04655MetoprineHistamine N-methyltransferasetarget
DB04690CamptothecinDNA topoisomerase 1target
DB04690CamptothecinMultidrug resistance protein 1transporter
DB04690CamptothecinATP-binding cassette sub-family G member 2transporter
DB04690CamptothecinSerum albumincarrier
DB04743NimesulideProstaglandin G/H synthase 2target
DB04743NimesulideGroup IIE secretory phospholipase A2target
DB04743NimesulideLactotransferrintarget
DB04743NimesulideCytochrome P450 3A4enzyme
DB04818IproniazidAmine oxidase [flavin-containing] Benzyme
DB04818IproniazidCytochrome P450 2D6enzyme
DB04818IproniazidCytochrome P450 2C9enzyme
DB04820NialamideAmine oxidase [flavin-containing] Btarget
DB04820NialamideAmine oxidase [flavin-containing] Atarget
DB04820NialamideCatechol O-methyltransferasetarget
DB04849CediranibVascular endothelial growth factor receptor 2target
DB04864Huperzine AAcetylcholinesterasetarget
DB04866HalofuginoneCollagen alpha-1(I) chaintarget
DB04866Halofuginone72 kDa type IV collagenasetarget
DB04876VildagliptinDipeptidyl peptidase 4target
DB04878VogliboseMaltase-glucoamylase, intestinaltarget
DB04879VatalanibVascular endothelial growth factor receptor 1target
DB04879VatalanibVascular endothelial growth factor receptor 2target
DB04879VatalanibVascular endothelial growth factor receptor 3target
DB04880EnoximonecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB04898XimelagatranProthrombintarget
DB04898XimelagatranCytochrome P450 2C9enzyme
DB04912StannsoporfinHeme oxygenase 1target
DB04912StannsoporfinHeme oxygenase 2target
DB04930PermethrinCytochrome P450 2B6enzyme
DB04930PermethrinCytochrome P450 3A4enzyme
DB04930PermethrinSodium channel protein type 1 subunit alphatarget
DB04930PermethrinEstrogen receptor alphatarget
DB04930PermethrinNuclear receptor subfamily 1 group I member 2target
DB04950RanpirnaseDNAtarget
DB05015BelinostatHistone deacetylasetarget
DB05015BelinostatCytochrome P450 1A2enzyme
DB05015BelinostatUDP-glucuronosyltransferase 1A1enzyme
DB05015BelinostatCytochrome P450 2C8enzyme
DB05015BelinostatCytochrome P450 2C9enzyme
DB05015BelinostatMultidrug resistance protein 1transporter
DB05022AmonafideDNA topoisomerase 2-alphatarget
DB05022AmonafideDNA topoisomerase 2-betatarget
DB05073SRT501NAD-dependent protein deacetylase sirtuin-1target
DB05088Tiomolibdate ionAmyloid beta A4 proteintarget
DB05161ElafinNeutrophil elastasetarget
DB05161ElafinMyeloblastintarget
DB05161ElafinMyeloperoxidaseenzyme
DB05262OxypurinolXanthine dehydrogenase/oxidasetarget
DB05265EcabetNADPH oxidase organizer 1target
DB05265EcabetUrease subunit alphatarget
DB05266IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB05266IbudilastcGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB05266IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB05266IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
DB05266IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB05289TarenflurbilNF-kappa-B essential modulatortarget
DB05351DexlansoprazolePotassium-transporting ATPase alpha chain 1target
DB05351DexlansoprazoleCytochrome P450 2C19enzyme
DB05351DexlansoprazoleCytochrome P450 3A4enzyme
DB05351DexlansoprazolePotassium-transporting ATPase subunit betatarget
DB05737Varespladib methylPhospholipase A2, membrane associatedtarget
DB05737Varespladib methylGroup 10 secretory phospholipase A2target
DB05812AbirateroneSteroid 17-alpha-hydroxylase/17,20 lyasetarget
DB05812AbirateroneSerum albumincarrier
DB05812AbirateroneAlpha-1-acid glycoprotein 1carrier
DB05812AbirateroneCytochrome P450 3A4enzyme
DB05812AbirateroneBile salt sulfotransferaseenzyme
DB05812AbirateroneMultidrug resistance-associated protein 1transporter
DB05812AbirateroneCytochrome P450 2D6enzyme
DB05812AbirateroneCytochrome P450 2C8enzyme
DB05812AbirateroneCytochrome P450 1A2enzyme
DB05812AbirateroneCytochrome P450 2C19enzyme
DB05812AbirateroneCytochrome P450 2C9enzyme
DB06159RubitecanDNA topoisomerase 1target
DB06160GarenoxacinCytochrome P450 1A2enzyme
DB06195SeliciclibCyclin-dependent kinase 1target
DB06195SeliciclibCyclin-dependent kinase 2target
DB06195SeliciclibMitogen-activated protein kinase 3target
DB06195SeliciclibMitogen-activated protein kinase 1target
DB06195SeliciclibCyclin-dependent kinase 7target
DB06195SeliciclibCyclin-dependent kinase 9target
DB06195SeliciclibCasein kinase I isoform epsilontarget
DB06195SeliciclibProstaglandin G/H synthase 2enzyme
DB06203AlogliptinDipeptidyl peptidase 4target
DB06203AlogliptinCytochrome P450 3A4enzyme
DB06203AlogliptinCytochrome P450 2D6enzyme
DB06228RivaroxabanCoagulation factor Xtarget
DB06228RivaroxabanCytochrome P450 3A4enzyme
DB06228RivaroxabanCytochrome P450 2J2enzyme
DB06228RivaroxabanMultidrug resistance protein 1transporter
DB06228RivaroxabanCytochrome P450 3A5enzyme
DB06228RivaroxabanATP-binding cassette sub-family G member 2transporter
DB06243EflornithineOrnithine decarboxylasetarget
DB06246ExisulindcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB06246ExisulindcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
DB06246ExisulindcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB06246ExisulindcGMP-dependent 3',5'-cyclic phosphodiesterasetarget
DB06246ExisulindGlutathione S-transferase Ptarget
DB06246ExisulindAldose reductasetarget
DB06246ExisulindAldo-keto reductase family 1 member B10target
DB06267UdenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB06267UdenafilCytochrome P450 3A4enzyme
DB06267UdenafilCytochrome P450 3A5enzyme
DB06290SimeprevirNS3 proteasetarget
DB06290SimeprevirSerum albumincarrier
DB06290SimeprevirCytochrome P450 1A2enzyme
DB06290SimeprevirMultidrug resistance protein 1transporter
DB06290SimeprevirSolute carrier organic anion transporter family member 1B1transporter
DB06290SimeprevirSolute carrier organic anion transporter family member 1B3transporter
DB06290SimeprevirCytochrome P450 3A4enzyme
DB06290SimeprevirCanalicular multispecific organic anion transporter 1transporter
DB06290SimeprevirATP-binding cassette sub-family G member 2transporter
DB06290SimeprevirSolute carrier organic anion transporter family member 2B1transporter
DB06290SimeprevirSodium/bile acid cotransportertransporter
DB06290SimeprevirBile salt export pumptransporter
DB06311DarapladibCytosolic phospholipase A2target
DB06335SaxagliptinDipeptidyl peptidase 4target
DB06335SaxagliptinCytochrome P450 3A4enzyme
DB06335SaxagliptinCytochrome P450 3A5enzyme
DB06335SaxagliptinMultidrug resistance-associated protein 1transporter
DB06335SaxagliptinSolute carrier organic anion transporter family member 4C1transporter
DB06335SaxagliptinSolute carrier family 22 member 8transporter
DB06358IclaprimDihydrofolate reductasetarget
DB06406IdraparinuxCoagulation factor Xtarget
DB06414EtravirineCytochrome P450 2C19enzyme
DB06414EtravirineCytochrome P450 2C9enzyme
DB06414EtravirineCytochrome P450 3A4enzyme
DB06414EtravirineGag-Pol polyproteintarget
DB06414EtravirineGag-Pol polyproteintarget
DB06414EtravirineMultidrug resistance protein 1transporter
DB06414EtravirineMultidrug resistance protein 3transporter
DB06433TezacitabineRibonucleoside-diphosphate reductase large subunittarget
DB06433TezacitabineThymidine phosphorylaseenzyme
DB06436SemaxanibVascular endothelial growth factor receptor 2target
DB06436SemaxanibProstaglandin G/H synthase 2enzyme
DB06595MidostaurinProtein kinase C alpha typetarget
DB06595MidostaurinVascular endothelial growth factor receptor 2target
DB06595MidostaurinMast/stem cell growth factor receptor Kittarget
DB06595MidostaurinPlatelet-derived growth factor receptor alphatarget
DB06595MidostaurinPlatelet-derived growth factor receptor betatarget
DB06595MidostaurinReceptor-type tyrosine-protein kinase FLT3target
DB06595MidostaurinCYP3Aenzyme
DB06595MidostaurinCytochrome P450 1A2enzyme
DB06595MidostaurinCytochrome P450 2B6enzyme
DB06595MidostaurinCytochrome P450 2C8enzyme
DB06595MidostaurinCytochrome P450 2C9enzyme
DB06595MidostaurinCytochrome P450 2C19enzyme
DB06595MidostaurinCytochrome P450 2D6enzyme
DB06595MidostaurinCytochrome P450 2E1enzyme
DB06595MidostaurinCytochrome P450 3A4enzyme
DB06595MidostaurinCytochrome P450 3A5enzyme
DB06595MidostaurinCytochrome P450 3A7enzyme
DB06595MidostaurinCytochrome P450 3A43enzyme
DB06603PanobinostatCytochrome P450 2D6enzyme
DB06603PanobinostatCytochrome P450 3A4enzyme
DB06603PanobinostatMultidrug resistance protein 1transporter
DB06603PanobinostatHistone deacetylasetarget
DB06605ApixabanCoagulation factor Xtarget
DB06605ApixabanCytochrome P450 3A4enzyme
DB06605ApixabanCytochrome P450 1A2enzyme
DB06605ApixabanCytochrome P450 2C8enzyme
DB06605ApixabanCytochrome P450 2C9enzyme
DB06605ApixabanCytochrome P450 2C19enzyme
DB06605ApixabanCytochrome P450 2J2enzyme
DB06605ApixabanMultidrug resistance protein 1transporter
DB06605ApixabanATP-binding cassette sub-family G member 2transporter
DB06605ApixabanCytochrome P450 3A5enzyme
DB06614PeramivirNeuraminidasetarget
DB06614PeramivirNeuraminidasetarget
DB06614PeramivirNeuraminidasetarget
DB06626AxitinibVascular endothelial growth factor receptor 1target
DB06626AxitinibVascular endothelial growth factor receptor 2target
DB06626AxitinibVascular endothelial growth factor receptor 3target
DB06626AxitinibCytochrome P450 3A4enzyme
DB06626AxitinibCytochrome P450 3A5enzyme
DB06626AxitinibCytochrome P450 1A2enzyme
DB06626AxitinibCytochrome P450 2C19enzyme
DB06626AxitinibUDP-glucuronosyltransferase 1-1enzyme
DB06626AxitinibMultidrug resistance protein 1transporter
DB06626AxitinibSolute carrier organic anion transporter family member 1B1transporter
DB06635OtamixabanCoagulation factor Xtarget
DB06692AprotininTrypsin-1target
DB06692AprotininChymotrypsinogen Btarget
DB06692AprotininPlasminogentarget
DB06692AprotininKallikrein-1target
DB06692AprotininCholinesteraseenzyme
DB06693Mevastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB06693MevastatinLiver carboxylesterase 1enzyme
DB06695Dabigatran etexilateProthrombintarget
DB06695Dabigatran etexilateMultidrug resistance protein 1transporter
DB06695Dabigatran etexilateLiver carboxylesterase 1enzyme
DB06695Dabigatran etexilateCocaine esteraseenzyme
DB06695Dabigatran etexilateUDP-glucuronosyltransferase 1-9enzyme
DB06695Dabigatran etexilateUDP-glucuronosyltransferase 2B7enzyme
DB06695Dabigatran etexilateUDP-glucuronosyltransferase 2B15enzyme
DB06695Dabigatran etexilateRibosyldihydronicotinamide dehydrogenase [quinone]enzyme
DB06704IobenguaneSodium-dependent noradrenaline transportertransporter
DB06732beta-NaphthoflavoneCytochrome P450 1A2enzyme
DB06732beta-NaphthoflavoneEstrogen receptor alphatarget
DB06732beta-NaphthoflavoneSteroid hormone receptor ERR1target
DB06732beta-NaphthoflavoneCOUP transcription factor 1target
DB06732beta-NaphthoflavoneAryl hydrocarbon receptortarget
DB06732beta-NaphthoflavoneCytochrome P450 1B1target
DB06733Bafilomycin A1V-type proton ATPase catalytic subunit Atarget
DB06771BesifloxacinDNA topoisomerase 4 subunit Atarget
DB06771BesifloxacinDNA topoisomerase 4 subunit Atarget
DB06771BesifloxacinDNA gyrase subunit Atarget
DB06771BesifloxacinDNA gyrase subunit Atarget
DB06771BesifloxacinCytochrome P450 1A2enzyme
DB06810PlicamycinDNAtarget
DB06817RaltegravirUDP-glucuronosyltransferase 1-1enzyme
DB06817RaltegravirIntegrasetarget
DB06827Viomycin70S ribosometarget
DB07232VeliparibPoly [ADP-ribose] polymerase 1target
DB07232VeliparibPoly [ADP-ribose] polymerase 2target
DB073474-(2-Aminoethyl)Benzenesulfonyl FluorideGlyceraldehyde-3-phosphate dehydrogenasetarget
DB073474-(2-Aminoethyl)Benzenesulfonyl FluorideV-type proton ATPase subunit B, brain isoformtarget
DB07348Brefeldin ACytohesin-2target
DB07348Brefeldin AADP-ribosylation factor 1target
DB07348Brefeldin ACytochrome P450 3A4enzyme
DB07374Anisomycin60S ribosomal protein L10-liketarget
DB07374Anisomycin60S ribosomal protein L13atarget
DB07374Anisomycin60S ribosomal protein L23target
DB07374Anisomycin60S ribosomal protein L15target
DB07374Anisomycin60S ribosomal protein L19target
DB07374Anisomycin60S ribosomal protein L23atarget
DB07374AnisomycinProbable ribosome biogenesis protein RLP24target
DB07374Anisomycin60S ribosomal protein L26-like 1target
DB07374Anisomycin60S ribosomal protein L8target
DB07374Anisomycin60S ribosomal protein L37target
DB07374Anisomycin60S ribosomal protein L3target
DB07374Anisomycin60S ribosomal protein L11target
DB07374AnisomycinNHP2-like protein 1target
DB07744Z-Val-Ala-Asp fluoromethyl ketoneCaspase-1target
DB079543-isobutyl-1-methyl-7H-xanthinecGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB079543-isobutyl-1-methyl-7H-xanthinecGMP-inhibited 3',5'-cyclic phosphodiesterase Btarget
DB079543-isobutyl-1-methyl-7H-xanthineHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7Atarget
DB079543-isobutyl-1-methyl-7H-xanthinecAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB079543-isobutyl-1-methyl-7H-xanthineHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9Atarget
DB079543-isobutyl-1-methyl-7H-xanthineHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8Atarget
DB079543-isobutyl-1-methyl-7H-xanthinecGMP-dependent 3',5'-cyclic phosphodiesterasetarget
DB079543-isobutyl-1-methyl-7H-xanthineRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DB079965-(2-methylpiperazine-1-sulfonyl)isoquinolinecAMP-dependent protein kinase catalytic subunit alphatarget
DB079965-(2-methylpiperazine-1-sulfonyl)isoquinolinecAMP-dependent protein kinase inhibitor alphatarget
DB08437Puromycin60S ribosomal protein L10-liketarget
DB08437Puromycin60S ribosomal protein L13atarget
DB08437Puromycin60S ribosomal protein L23target
DB08437Puromycin60S ribosomal protein L15target
DB08437Puromycin60S ribosomal protein L19target
DB08437Puromycin60S ribosomal protein L23atarget
DB08437PuromycinProbable ribosome biogenesis protein RLP24target
DB084