Cytochrome P-450 CYP1A2 Substrates

Name
Cytochrome P-450 CYP1A2 Substrates
Accession Number
DBCAT002609
Description
Not Available
Drugs
DrugDrug Description
BortezomibA proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies.
CaffeineA stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth.
AnagrelideA platelet-reducing agent used to treat thrombocythemia, and its related complications, secondary to myeloproliferative neoplasms.
RopiniroleA non-ergoline dopamine agonist used to treat the symptoms of Parkinson's disease and Restless Legs Syndrome.
TheophyllineA xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction.
LidocaineA local anesthetic used in a wide variety of superficial and invasive procedures.
Conjugated estrogensA mixture of estrogens used in estrogen replacement therapy for menopause and hypoestrogenism, used in the treatment of various malignancies, and used in the treatment of postmenopausal osteoporosis.
RopivacaineAn analgesic drug used for local or regional anesthesia for surgery and short-term management of pain.
ZolmitriptanA member of the triptan class of 5-HT(1B/1D/1F) receptor agonist drugs used for the acute treatment of migraine with or without aura in adults.
AmitriptylineA tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety.
OlanzapineAn antipsychotic drug used in the management of schizophrenia, bipolar 1 disorder, and agitation associated with these disorders.
ClozapineAn antipsychotic drug used in treatment resistant schizophrenia and to decrease suicide risk in schizophrenic patients.
GrepafloxacinA fluoroquinolone antibiotic used to treat various gram positive and gram negative bacterial infections.
MirtazapineA tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite.
MexiletineA class 1B antiarrhythmic agent used in the treatment of documented ventricular arrhythmias that warrant treatment.
TacrineFor the palliative treatment of mild to moderate dementia of the Alzheimer's type.
ImipramineA tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis.
DuloxetineA serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence.
FlutamideAn antiandrogen used for locally confined stage B2-C and D-2 metastatic prostate carcinoma.
HaloperidolAn antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium.
NortriptylineA tricyclic antidepressant used in the treatment of depression.
FluorouracilA pyrimidine analog used to treat basal cell carcinomas, and as an injection in palliative cancer treatment.
PropranololA non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma.
EstroneAn estrogen used to treat perimenopausal and postmenopausal symptoms.
VerapamilA non-dihydropyridine calcium channel blocker used in the treatment of angina, arrhythmia, and hypertension.
WarfarinA vitamin K antagonist used to treat venous thromboembolism, pulmonary embolism, thromboembolism with atrial fibrillation, thromboembolism with cardiac valve replacement, and thromboembolic events post myocardial infarction.
TizanidineAn alpha-2 adrenergic agonist used for the short-term treatment of muscle spasticity.
RiluzoleA glutamate antagonist used to treat amyotrophic lateral sclerosis.
ZileutonA leukotriene synthesis inhibitor used in the prophylaxis and treatment of chronic asthma.
EstradiolAn estrogenic steroid used to treat vasomotor symptoms of vulvar and vaginal atrophy in menopause, hypoestrogenism, prevention of postmenopausal osteoporosis, treatment of breast cancer, and advanced androgen-dependent carcinoma of the prostate.
DacarbazineAn antineoplastic agent used to treat malignant melanoma and Hodgkin's disease.
OndansetronA serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting in cancer chemotherapy and postoperatively.
CyclobenzaprineA skeletal muscle relaxant that works on the brainstem to treat muscle spasms of local origin.
RamelteonA melatonin receptor agonist used to treat insomnia.
FrovatriptanA 5-HT1B/1D receptor agonist used to treat migraines.
LevobupivacaineFor the production of local or regional anesthesia for surgery and obstetrics, and for post-operative pain management
CinacalcetA calcium sensing receptor agonist used to treat secondary hyperparathyroidism in chronic kidney disease and hypercalcemia in parathyroid carcinoma.
PimozideAn antipsychotic used to manage debilitating motor and phonic tics in patients with Tourette's Disorder.
PropafenoneA Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias.
ClomipramineA tricyclic antidepressant used in the treatment of obsessive-compulsive disorder and disorders with an obsessive-compulsive component, such as depression, schizophrenia, and Tourette’s disorder.
RasagilineAn irreversible inhibitor of monoamine oxidase used for the symptomatic management of idiopathic Parkinson's disease as initial monotherapy and as adjunct therapy to levodopa.
ChlorzoxazoneA drug with muscle relaxant properties that is used as an adjunct to physical therapy and analgesics to treat stiffness and pain caused by a variety of musculoskeletal conditions.
ChlorpromazineA phenothiazine antipsychotic used to treat nausea, vomiting, preoperative anxiety, schizophrenia, bipolar disorder, and severe behavioral problems in children.
MephenytoinA phenylhydantoin used to treat refractory partial epilepsy.
DiclofenacAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
AzelastineA histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis.
AcenocoumarolAn anticoagulant drug used in the prevention of thromboembolic diseases in infarction and transient ischemic attacks, as well as management of deep vein thrombosis and myocardial infarction.
AminophenazoneFormerly widely used as an antipyretic and analgesic in rheumatism, neuritis, and common colds. Currently used to measure total body water.
PalonosetronA serotonin antagonist used in the prophylaxis or management of vomiting that results from emetogenic chemotherapy, and for the management of postoperative nausea and vomiting.
MelatoninAn endogenous hormone produced by the pineal gland that regulates sleep-wake cycles and when provided exogenously has beneficial effects on sleep-onset latency; available as an over-the-counter supplement.
ImatinibA tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.
QuinineAn alkaloid used to treat uncomplicated Plasmodium falciparum malaria.
DoxepinA psychotropic agent used for the treatment of depression, anxiety, manic-depressive disorder, and insomnia.
CarbamazepineAn anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia.
ZolpidemA sedative hypnotic used for the short-term treatment of insomnia to improve sleep latency.
FluoxetineA selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I.
AntipyrineAn antipyretic agent used for the symptomatic treatment of acute otitis media, most commonly in combination with benzocaine.
TerbinafineAn allylamine antifungal used to treat dermatophyte infections of toenails and fingernails as well as other fungal skin infections.
CinnarizineFor the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
FlunarizineA selective calcium-entry blocker used as migraine prophylaxis in patients with severe and frequent episodes who have not responded adequately to more common treatments.
NaproxenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain.
PhenacetinUsed principally as an analgesic.
AminophyllineA bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.
AsenapineAn atypical antipsychotic used to treat patients with bipolar I disorder and patients with schizophrenia.
BetaxololA cardioselective beta blocking agent commonly used to treat hypertension and elevated intraocular pressure (when administered ophthalmically).
Estrone sulfateAn estrogen used as monotherapy or in several combination hormone replacement products for managing menopause symptoms and hormone disorders.
GuanabenzAn alpha-2 adrenergic agonist used to treat hypertension.
ThiothixeneAn antipsychotic indicated for the management of schizophrenia.
TrifluoperazineA phenothiazine used to treat depression, anxiety, and agitation.
PromazineA phenothiazine used to manage schizophrenia.
CarvedilolA non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients.
GenisteinCurrently Genistein is being studied in clinical trials as a treatment for prostate cancer.
ResveratrolBeing investigated for the treatment of Herpes labialis infections (cold sores).
AlbendazoleA benzimidazole anthelmintic used to treat parenchymal neurocysticercosis and other helminth infections.
BromazepamA short-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and severe anxiety.
DesipramineA tricyclic antidepressant used in the treatment of depression.
DexfenfluramineFor the management of obesity including weight loss and maintenance of weight loss in patients on a reduced calorie diet
DomperidoneA dopamine receptor antagonist used as a peristaltic stimulant and anti-emetic agent for dyspepsia, indigestion, epigastric pain, nausea, and vomiting.
EthanolFor therapeutic neurolysis of nerves or ganglia for the relief of intractable chronic pain in such conditions as inoperable cancer and trigeminal neuralgia (tic douloureux), in patients for whom neurosurgical...
EtoposideA podophyllotoxin derivative used to treat testicular and small cell lung tumors.
LumiracoxibFor the acute and chronic treatment of the signs and symptoms of osteoarthritis of the knee in adults.
MalathionA parasympathomimetic organophosphate used to treat head lice.
MaprotilineA tetracyclic antidepressant used to treat depressive illness, major depressive disorder, bipolar disorder, and anxiety associated with depression.
MethadoneAn opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction.
MethoxyfluraneFor use in the induction and maintenance of general anesthesia
MianserinFor the treatment of depression.
PentoxifyllineA methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs.
PerphenazineA phenothiazine used to treat schizophrenia as well as nausea and vomiting.
SelegilineA monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's.
Theobrominetheobromine is used as a vasodilator, a diuretic, and heart stimulant. And similar to caffeine, it may be useful in management of fatigue and orthostatic hypotension.
TolperisoneInvestigated for use/treatment in neurologic disorders, spinal cord injuries, muscle spasm, back pain, and multiple sclerosis.
ErlotinibAn EGFR tyrosine kinase inhibitor used to treat certain small cell lung cancers or advanced metastatic pancreatic cancers.
CilostazolAn antiplatelet agent and vasodilator used for the symptomatic relief of intermittent claudication.
EltrombopagA thrombopoietin receptor agonist used to treat thrombocytopenia or aplastic anemia associated with various etiologies.
ClonidineAn alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines.
MuraglitazarInvestigated for use/treatment in diabetes mellitus type 2.
VadimezanInvestigated for use/treatment in solid tumors, lung cancer, ovarian cancer, and prostate cancer.
NabumetoneAn NSAID used to treat osteoarthritis and rheumatoid arthritis.
PazopanibAn antineoplastic agent used in the treatment of advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy.
UlipristalA selective progesterone receptor modulator used for emergency contraception after unprotected intercourse or in a situation where a planned method of contraception has failed.
LorcaserinA serotonin 2C receptor agonist used in conjunction with physical activity and calorie restriction for weight loss in obese patients with a body mass index (BMI) of 30 and above, and in overweight patients with weight-related comorbidities.
ApixabanAn anticoagulant used for the prophylaxis of stroke and systemic embolism in nonvalvular atrial fibrillation, and deep vein thrombosis(DVT) leading to pulmonary embolism(PE), including in patients after a hip or knee replacement surgery.
AxitinibAn oral VEGFR and kinase inhibitor used for the treatment of advanced renal cell carcinoma after failure of one prior systemic therapy.
PomalidomideA thalidomide analogue used in combination with dexamethasone to treat patients with multiple myeloma.
IxazomibA monoclonal antibody used with other medications to treat multiple myeloma in patients who have received one other therapy already.
BendamustineAn antineoplastic agent used for the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed following rituximab therapy.
RucaparibAn anti-cancer agent used to treat recurrent ovarian, fallopian tube, or peritoneal cancer.
IcotinibIcotinib hydrochloride is a novel epidermal growth factor receptor (EGFR)–tyrosine kinase inhibitor, exhibits encouraging efficacy and tolerability in patients with advanced non-small-cell lung cancer (NSCLC) who failed previous chemotherapy.
DeutetrabenazineA vesicular monoamine transporter 2 inhibitor used for the symptomatic treatment of chorea in Huntington's disease and tardive dyskinesia.
StiripentolAn anticonvulsant agent used with clobazam and valproate as an adjunct to treat refractory generalized tonic-clonic seizures in Dravet syndrome.
VoxilaprevirA nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections.
EnasidenibAn isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation.
Estradiol acetateAn estrogen used to treat vasomotor symptoms and moderate to severe vulvar and vaginal atrophy from menopause.
Estradiol benzoateEstradiol benzoate is not currently available in any FDA or Health Canada approved products.
Estradiol cypionateAn estradiol prodrug used to treat vasomotor symptoms and hypoestrogenisms from hypogonadism.
Estradiol dienanthateEstradiol dienanthate is not currently available in any FDA or Health Canada approved products.
Estradiol valerateAn estradiol prodrug used to treat some effects of menopause, hypoestrogenism, androgen dependant carcinoma of the prostate, and in combination products for endometriosis and contraception.
ZotepineZotepine, like other atypical antipsychotics, is considered as the first-line treatment in newly diagnosed schizophrenia. It is usually thought to be an option of choice for managing acute schizophrenic episodes...
LofexidineA centrally acting alpha2-adrenergic agonist used for the symptomatic treatment of acute opioid withdrawal syndrome to facilitate abrupt opioid discontinuation in adults.
TasimelteonA melatonin receptor agonist used to treat Non- 24-Hour Sleep-Wake Disorder.
PirfenidoneAn agent used for the treatment of idiopathic pulmonary fibrosis (IPF).
RamosetronFor the treatment of nausea and vomiting and diarrhea-predominant irritable bowel syndrome in males.
AcetaminophenAn analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent.
ClopidogrelAn antiplatelet agent used to prevent blood clots in peripheral vascular disease, coronary artery disease, and cerebrovascular disease.
FluvoxamineA selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder.
TegafurAn antineoplastic agent used in combination with other anticancer medications to treat advanced gastric and colorectal cancers.
DihydralazineDihydralazine is under investigation in clinical trial NCT00311974 (The Effect of Dihydralazine on Kidney Function and Hormones in Healthy Individuals).
PimobendanNot Annotated
RanitidineA histamine H2 antagonist used to treat duodenal ulcers, Zollinger-Ellison syndrome, gastric ulcers, GERD, and erosive esophagitis.
PerampanelA non-competitive AMPA glutamate receptor antagonist used to treat partial-onset seizures with or without secondarily generalized seizures, and as adjunctive treatment of primary generalized tonic-clonic seizures in patients with epilepsy.
(R)-warfarinWarfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways. S-warfarin is 2-5 times more potent than the R-isomer in...
6-O-benzylguanine6-O-benzylguanine has been used in trials studying the treatment of HIV Infection, Adult Gliosarcoma, Adult Glioblastoma, Stage I Adult Hodgkin Lymphoma, and Stage II Adult Hodgkin Lymphoma, among others.
8-chlorotheophyllineWhen used in combination with DB01075 as the antiemetic DB00985, 8-chlorotheophylline is indicated for the prevention and treatment of nausea, vomiting, or vertigo of motion sickness.
HypoxanthineHypoxanthine is a purine and a reaction intermediate in the metabolism of adenosine and in the formation of nucleic acids by the salvage pathway.
LisofyllineLisofylline has been investigated for the treatment of Type 1 Diabetes Mellitus.
OxtriphyllineA bronchodilator used for the treatment of asthma, bronchitis, COPD, and emphysema.
XanthineA purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is an intermediate in the degradation of adenosine monophosphate to uric acid, being...
TemafloxacinFor the treatment of lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections.
AcefyllineNot Annotated
AcyclovirA guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster.
BamifyllineBamifylline is a selective A1 adenosine receptor antagonist.
BromotheophyllineBromotheophylline is used as a diuretic and also, in combination with DB00316, it is used for the relief of temporary water weight gain, bloating, swelling and full feeling associated with...
BufyllineNot Annotated
CafedrineCafedrine is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
DoxofyllineIndicated for the treatment of chronic obstructive pulmonary disease (COPD), bronchial asthma and pulmonary disease with spastic bronchial component.
EntecavirA nucleoside analogue used in the treatment of chronic hepatitis B for patients with active viral replication, histological evidence of active disease, or persistent elevations in liver transaminases.
EtamiphyllineNot Annotated
FenethyllineNot Available
LobucavirLobucavir has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.
PeldesinePeldesine is a potent inhibitor of human CCRF-CEM T-cell proliferation. It has undergone phase I trials for the treatment of Human Immunodeficiency Virus (HIV) infections.
PemetrexedA folate analog used to treat mesothelioma and non-small cell lung cancer.
PenciclovirA topical nucleoside polymerase inhibitor used in the treatment of recurrent herpes labialis.
PentifyllineNot Annotated
PropentofyllineInvestigated for use/treatment in alzheimer's disease.
ProxyphyllineNot Annotated
TheodrenalineTheodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
PropacetamolPropacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy.
NicotineA stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation.
CarmustineAn alkylating agent used in the treatment of various malignancies, including brain tumours and multiple myeloma, among others.
LomefloxacinA fluoroquinolone used to prevent and treat a wide variety of infections in the body.
HesperetinFor lowering cholesterol and, possibly, otherwise favorably affecting lipids. In vitro research also suggests the possibility that hesperetin might have some anticancer effects and that it might have some anti-aromatase...
LeflunomideA pyrimidine synthesis inhibitor indicated to treat rheumatoid arthritis.
RofecoxibA COX-2 inhibitor NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, primary dysmenorrhea, and migraine attacks.
ThiabendazoleA benzimidazole used in the treatment of strongyloides, cutaneous larva migrans, visceral larva migrans, and trichinosis infections.
NifedipineA dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension.
PrimaquineAn antimalarial indicated to prevent relapse of vivax malaria.
EtoricoxibFor the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout.
PraziquantelAn anthelmintic medication used to treat a number of parasitic worm infections such as schistosomiasis.
TriamtereneA potassium-sparing diuretic used in the treatment of edema and in the management of hypertension.
DasatinibA tyrosine kinase inhibitor used for the treatment of lymphoblastic or chronic myeloid leukemia with resistance or intolerance to prior therapy.
Benzyl alcoholAn antiparasitic agent used for the topical treatment of head lice infestation in patients 6 months of age and older.
CapsaicinA topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain.
BinimetinibA medication used to treat metastatic melanoma with specific mutations.
AzathioprineAn immunosuppressant used to prevent renal transplant rejection, treat rheumatoid arthritis, Crohn's disease, and ulcerative colitis.
8-azaguanine8-azaguanine is one of the early purine analogs showing antineoplastic activity. It functions as an antimetabolite and is easily incorporated into ribonucleic acids.
9-DeazaguanineNot Available
9-MethylguanineNot Available
DisopyramideA class 1A antiarrhythmic agent used to treat life-threatening ventricular arrhythmias.
AlosetronA 5-HT3 antagonist used to treat diarrhea-predominant IBS.
SorafenibA kinase inhibitor used in the treatment of unresectable liver carcinoma and advanced renal carcinoma.
AgomelatineAgomelatine is indicated to treat major depressive episodes in adults.
TocainideAn orally active class 1b antiarrhythmic agent that interferes with cardiac sodium channels and typically used to treat ventricular arrhythmias.
TriclabendazoleAn anthelmintic drug used to treat fascioliasis.
DapagliflozinA sodium-glucose cotransporter 2 inhibitor used in the management of type 2 diabetes mellitus.
ApremilastA non-steroidal medication used for the treatment of inflammatory conditions such as psoriasis and psoriatic arthritis.
ParoxetineA selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder.
TamoxifenA selective estrogen receptor modulator used to treat estrogen receptor positive breast cancer, reduce the risk of invasive breast cancer following surgery, or reduce the risk of breast cancer in high risk women.
IstradefyllineA selective adenoside A2A receptor antagonist indicated in adjunct to levodopa and carbidopa for the treatment of Parkinson's Disease.
EfavirenzA non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV.
MetoclopramideAn antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying.
LoratadineA second generation antihistamine used to manage the symptoms of allergic rhinitis.
GTS-21Investigated for use/treatment in alzheimer's disease and schizophrenia and schizoaffective disorders.
BicifadineFor the treatment of pain.
FlecainideA class Ic antiarrhythmic agent used to manage atrial fibrillation and paroxysmal supraventricular tachycardias (PSVT).
NorethisteroneA synthetic second-generation progestin used for contraception, prevention of endometrial hyperplasia in hormone replacement therapy, and in the treatment of other hormone-mediated illnesses such as endometriosis.
LumateperoneA novel 2nd generation antipsychotic used to manage both positive and negative symptoms in patients with schizophrenia.
EthinylestradiolAn estradiol used as a contraceptive.
TrimethoprimAn antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract.
UmifenovirA dual direct-acting antiviral/host-targeting agent used in the treatment and prophylaxis of influenza and other respiratory viruses.
LopinavirAn HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection.
SelumetinibA MEK 1/2 inhibitor used in pediatric patients to treat neurofibromatosis type 1 (NF1) accompanied by symptomatic, inoperable plexiform neurofibromas (PN).
FenfluramineFenfluramine is a phenethylamine that is structurally similar to serotonin. Due to its ability to increase extracellular serotonin levels, modulate serotonergic and other neurologic receptors, and control neurotransmission, it is effective in treating pharmacoresistant seizures.
Drugs & Drug Targets
DrugTargetType
BortezomibCytochrome P450 3A4enzyme
BortezomibCytochrome P450 2C19enzyme
BortezomibCytochrome P450 1A2enzyme
BortezomibCytochrome P450 2D6enzyme
BortezomibCytochrome P450 2C9enzyme
BortezomibProteasome subunit beta type-5target
BortezomibProteasome subunit beta type-1target
BortezomibP-glycoprotein 1transporter
BortezomibSolute carrier organic anion transporter family member 1B3transporter
CaffeineAdenosine receptor A1target
CaffeinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
CaffeineAdenosine receptor A2atarget
CaffeineCytochrome P450 1A2enzyme
CaffeineRyanodine receptor 1target
CaffeineCytochrome P450 3A4enzyme
CaffeineCytochrome P450 2E1enzyme
CaffeineCytochrome P450 2C8enzyme
CaffeineCytochrome P450 2C9enzyme
CaffeineCytochrome P450 1A1enzyme
CaffeineCytochrome P450 1B1enzyme
CaffeineCytochrome P450 2D6enzyme
CaffeineCyclic nucleotide phosphodiesterasetarget
CaffeineDNA-dependent protein kinase catalytic subunittarget
CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformtarget
CaffeineInositol 1,4,5-trisphosphate receptortarget
CaffeineSerine-protein kinase ATMtarget
CaffeineATP-binding cassette sub-family G member 2transporter
CaffeineAdenosine receptor A2btarget
CaffeineAdenosine receptor A3target
CaffeinePhosphodiesterase enzymestarget
AnagrelidecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
AnagrelideCytochrome P450 1A2enzyme
RopiniroleDopamine D2 receptortarget
RopiniroleDopamine D3 receptortarget
RopiniroleDopamine D4 receptortarget
RopiniroleCytochrome P450 1A2enzyme
RopiniroleAlpha adrenergic receptortarget
TheophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
TheophyllineAdenosine receptor A2btarget
TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
TheophyllinecGMP-specific 3',5'-cyclic phosphodiesterasetarget
TheophyllineAdenosine receptor A1target
TheophyllineAdenosine receptor A2atarget
TheophyllineCytochrome P450 1A2enzyme
TheophyllineAdenosine deaminaseenzyme
TheophyllineCytochrome P450 2E1enzyme
TheophyllineCytochrome P450 3A4enzyme
TheophyllineSolute carrier family 22 member 7transporter
TheophyllineCytochrome P450 1A1enzyme
TheophyllineCytochrome P450 1B1enzyme
TheophyllineCytochrome P450 2D6enzyme
TheophyllineHistone deacetylase 2target
TheophyllineCopine-1target
TheophyllineMinor histocompatibility antigen H13target
TheophyllineNodal modulator 1target
TheophyllinePoly [ADP-ribose] polymerase 1target
TheophyllineProtein RIC-3target
TheophyllineTubulin monoglycylase TTLL3target
LidocaineSodium channel protein type 5 subunit alphatarget
LidocaineSodium channel protein type 10 subunit alphatarget
LidocaineEpidermal growth factor receptortarget
LidocaineSodium channel protein type 9 subunit alphatarget
LidocaineCytochrome P450 1A2enzyme
LidocaineCytochrome P450 2D6enzyme
LidocaineCytochrome P450 3A4enzyme
LidocaineCytochrome P450 3A5enzyme
LidocaineCytochrome P450 3A7enzyme
LidocaineSolute carrier family 22 member 5transporter
LidocaineP-glycoprotein 1transporter
LidocaineCytochrome P450 2A6enzyme
LidocaineCytochrome P450 2B6enzyme
LidocaineCytochrome P450 2C8enzyme
LidocaineCytochrome P450 2C9enzyme
LidocaineSodium channel protein type 4 subunit alphatarget
LidocaineAlpha-1-acid glycoprotein 1target
LidocaineAlpha-1-acid glycoprotein 2target
Conjugated estrogensEstrogen receptor alphatarget
Conjugated estrogensCytochrome P450 3A4enzyme
Conjugated estrogensCytochrome P450 1A2enzyme
Conjugated estrogensCatechol O-methyltransferaseenzyme
Conjugated estrogensCanalicular multispecific organic anion transporter 2transporter
Conjugated estrogensMultidrug resistance-associated protein 4transporter
Conjugated estrogensMultidrug resistance-associated protein 1transporter
Conjugated estrogensSolute carrier organic anion transporter family member 1A2transporter
Conjugated estrogensSodium/bile acid cotransportertransporter
Conjugated estrogensSolute carrier family 22 member 10transporter
Conjugated estrogensSolute carrier family 22 member 8transporter
Conjugated estrogensSolute carrier organic anion transporter family member 1C1transporter
Conjugated estrogensSolute carrier organic anion transporter family member 1B1transporter
Conjugated estrogensSolute carrier organic anion transporter family member 2B1transporter
Conjugated estrogensP-glycoprotein 1transporter
Conjugated estrogensSolute carrier family 22 member 6transporter
Conjugated estrogensOrganic solute transporter subunit alphatransporter
Conjugated estrogensOrganic solute transporter subunit betatransporter
Conjugated estrogensCanalicular multispecific organic anion transporter 1transporter
Conjugated estrogensSolute carrier organic anion transporter family member 4A1transporter
Conjugated estrogensATP-binding cassette sub-family C member 11transporter
Conjugated estrogensSolute carrier organic anion transporter family member 1B3transporter
Conjugated estrogensSolute carrier family 22 member 11transporter
Conjugated estrogensSolute carrier organic anion transporter family member 3A1transporter
Conjugated estrogensATP-binding cassette sub-family G member 2transporter
Conjugated estrogensThyroxine-binding globulincarrier
Conjugated estrogensSex hormone-binding globulincarrier
Conjugated estrogensSerum albumincarrier
Conjugated estrogensEstrogen receptor betatarget
RopivacaineSodium channel protein type 10 subunit alphatarget
RopivacaineCytochrome P450 1A2enzyme
RopivacaineCytochrome P450 2B6enzyme
RopivacaineCytochrome P450 3A4enzyme
Zolmitriptan5-hydroxytryptamine receptor 1Dtarget
Zolmitriptan5-hydroxytryptamine receptor 1Btarget
Zolmitriptan5-hydroxytryptamine receptor 1Ftarget
ZolmitriptanCytochrome P450 1A2enzyme
ZolmitriptanAmine oxidase [flavin-containing] Aenzyme
Zolmitriptan5-hydroxytryptamine receptor 1Atarget
ZolmitriptanP-glycoprotein 1transporter
Zolmitriptan5-hydroxytryptamine receptor 7target
Zolmitriptan5-hydroxytryptamine receptor 2Atarget
Zolmitriptan5-hydroxytryptamine receptor 2Btarget
Zolmitriptan5-hydroxytryptamine receptor 1Etarget
AmitriptylineSodium-dependent serotonin transportertarget
AmitriptylineSodium-dependent noradrenaline transportertarget
AmitriptylinePotassium voltage-gated channel subfamily KQT member 2target
AmitriptylineAlpha-2A adrenergic receptortarget
AmitriptylineCytochrome P450 1A2enzyme
AmitriptylineCytochrome P450 2C19enzyme
AmitriptylineCytochrome P450 2D6enzyme
AmitriptylineSerum albumincarrier
AmitriptylineAlpha-1-acid glycoprotein 1carrier
AmitriptylineHistamine H1 receptortarget
Amitriptyline5-hydroxytryptamine receptor 2Atarget
Amitriptyline5-hydroxytryptamine receptor 1Atarget
AmitriptylineAlpha-1A adrenergic receptortarget
AmitriptylineCytochrome P450 3A4enzyme
AmitriptylineCytochrome P450 3A5enzyme
AmitriptylinePotassium voltage-gated channel subfamily A member 1target
AmitriptylineAlpha-1D adrenergic receptortarget
AmitriptylineDelta-type opioid receptortarget
AmitriptylineKappa-type opioid receptortarget
AmitriptylineHigh affinity nerve growth factor receptortarget
AmitriptylineBDNF/NT-3 growth factors receptortarget
AmitriptylineCytochrome P450 2C9enzyme
AmitriptylineCytochrome P450 2B6enzyme
AmitriptylineCytochrome P450 2C8enzyme
AmitriptylineHistamine H2 receptortarget
AmitriptylineHistamine H4 receptortarget
AmitriptylineSigma non-opioid intracellular receptor 1target
Amitriptyline5-hydroxytryptamine receptor 2Ctarget
AmitriptylineAlpha-1B adrenergic receptortarget
Amitriptyline5-hydroxytryptamine receptor 7target
Amitriptyline5-hydroxytryptamine receptor 1Dtarget
AmitriptylineMu-type opioid receptortarget
Amitriptyline5-hydroxytryptamine receptor 1Btarget
Amitriptyline5-hydroxytryptamine receptor 6target
AmitriptylinePotassium voltage-gated channel subfamily KQT member 3target
AmitriptylineUDP-glucuronosyltransferase 2B10enzyme
Amitriptyline5-hydroxytryptamine receptor 1Ctarget
AmitriptylineMuscarinic acetylcholine receptortarget
AmitriptylineHERG human cardiac K+ channeltarget
AmitriptylineP-glycoprotein 1transporter
AmitriptylineUDP-glucuronosyltransferase 1-4enzyme
OlanzapineDopamine D1 receptortarget
OlanzapineMuscarinic acetylcholine receptor M1target
OlanzapineMuscarinic acetylcholine receptor M3target
Olanzapine5-hydroxytryptamine receptor 2Atarget
OlanzapineDopamine D4 receptortarget
OlanzapineHistamine H1 receptortarget
OlanzapineMuscarinic acetylcholine receptor M4target
OlanzapineMuscarinic acetylcholine receptor M2target
OlanzapineDopamine D2 receptortarget
Olanzapine5-hydroxytryptamine receptor 2Ctarget
OlanzapineDopamine D3 receptortarget
OlanzapineAlpha-1B adrenergic receptortarget
OlanzapineCytochrome P450 1A2enzyme
Olanzapine5-hydroxytryptamine receptor 3Atarget
Olanzapine5-hydroxytryptamine receptor 6target
OlanzapineAlpha-1A adrenergic receptortarget
OlanzapineDopamine D5 receptortarget
OlanzapineSerum albumincarrier
OlanzapineAlpha-1-acid glycoprotein 1carrier
OlanzapineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
OlanzapineCytochrome P450 2D6enzyme
OlanzapineP-glycoprotein 1transporter
OlanzapineCytochrome P450 2C19enzyme
OlanzapineD(1) dopamine receptortarget
OlanzapineBeta adrenergic receptortarget
Olanzapine5-hydroxytryptamine receptor 1target
OlanzapineGABA(A) Receptor Benzodiazepine Binding Sitetarget
OlanzapineCytochrome P450 2C9enzyme
OlanzapineUDP-glucuronosyltransferase 1-4enzyme
OlanzapineCytochrome P450 3A4enzyme
OlanzapineCytochrome P450 3A Subfamilyenzyme
ClozapineDopamine D4 receptortarget
ClozapineHistamine H1 receptortarget
ClozapineDopamine D2 receptortarget
ClozapineNeuron-specific vesicular protein calcyontarget
ClozapineHistamine H4 receptortarget
Clozapine5-hydroxytryptamine receptor 2Atarget
Clozapine5-hydroxytryptamine receptor 1Atarget
Clozapine5-hydroxytryptamine receptor 2Ctarget
ClozapineDopamine D1 receptortarget
ClozapineCytochrome P450 1A2enzyme
ClozapineCytochrome P450 2D6enzyme
ClozapineDopamine D3 receptortarget
ClozapineMuscarinic acetylcholine receptor M1target
ClozapineMuscarinic acetylcholine receptor M2target
ClozapineMuscarinic acetylcholine receptor M3target
ClozapineMuscarinic acetylcholine receptor M4target
ClozapineMuscarinic acetylcholine receptor M5target
Clozapine5-hydroxytryptamine receptor 1Btarget
Clozapine5-hydroxytryptamine receptor 1Dtarget
Clozapine5-hydroxytryptamine receptor 1Etarget
Clozapine5-hydroxytryptamine receptor 3Atarget
Clozapine5-hydroxytryptamine receptor 6target
Clozapine5-hydroxytryptamine receptor 7target
ClozapineAlpha-1A adrenergic receptortarget
ClozapineAlpha-1B adrenergic receptortarget
ClozapineAlpha-2A adrenergic receptortarget
ClozapineAlpha-2B adrenergic receptortarget
ClozapineAlpha-2C adrenergic receptortarget
ClozapineCytochrome P450 2C9enzyme
ClozapineP-glycoprotein 1transporter
ClozapineCytochrome P450 3A4enzyme
ClozapineCytochrome P450 2C19enzyme
ClozapineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
ClozapineUDP-glucuronosyltransferase 1-4enzyme
ClozapineCytochrome P450 1A1enzyme
ClozapineCytochrome P450 2A6enzyme
ClozapineCytochrome P450 2C8enzyme
ClozapineGlutathione S-transferase Ptarget
GrepafloxacinDNA gyrase subunit Atarget
GrepafloxacinDNA topoisomerase 4 subunit Atarget
GrepafloxacinCytochrome P450 3A4enzyme
GrepafloxacinCytochrome P450 1A2enzyme
GrepafloxacinSolute carrier family 22 member 2transporter
GrepafloxacinSolute carrier family 22 member 5transporter
GrepafloxacinCanalicular multispecific organic anion transporter 1transporter
GrepafloxacinP-glycoprotein 1transporter
GrepafloxacinMultidrug resistance-associated protein 1transporter
GrepafloxacinSolute carrier family 22 member 6transporter
Mirtazapine5-hydroxytryptamine receptor 2Atarget
Mirtazapine5HT3 serotonin receptortarget
MirtazapineAlpha-2A adrenergic receptortarget
Mirtazapine5-hydroxytryptamine receptor 2Ctarget
MirtazapineKappa-type opioid receptortarget
MirtazapineHistamine H1 receptortarget
MirtazapineCytochrome P450 1A2enzyme
MirtazapineCytochrome P450 3A4enzyme
MirtazapineCytochrome P450 2D6enzyme
MirtazapineAlpha-1 adrenergic receptorstarget
MirtazapineSodium-dependent serotonin transportertransporter
MexiletineSodium channel protein type 5 subunit alphatarget
MexiletineCytochrome P450 1A2enzyme
MexiletineCytochrome P450 2D6enzyme
MexiletineCytochrome P450 2B6enzyme
MexiletineCytochrome P450 2E1enzyme
MexiletineCytochrome P450 3A4enzyme
MexiletineAryl hydrocarbon receptortarget
TacrineAcetylcholinesterasetarget
TacrineCytochrome P450 1A2enzyme
TacrineCholinesterasetarget
TacrineP-glycoprotein 1transporter
TacrineLiver carboxylesterase 1target
ImipramineSodium-dependent noradrenaline transportertarget
ImipramineSodium-dependent serotonin transportertarget
ImipramineCytochrome P450 1A2enzyme
ImipramineCytochrome P450 2C19enzyme
ImipramineCytochrome P450 2D6enzyme
ImipramineHistamine H1 receptortarget
ImipramineAlpha-1A adrenergic receptortarget
Imipramine5-hydroxytryptamine receptor 2Atarget
ImipramineMuscarinic acetylcholine receptor M1target
ImipramineMuscarinic acetylcholine receptor M2target
ImipramineMuscarinic acetylcholine receptor M3target
ImipramineMuscarinic acetylcholine receptor M4target
ImipramineMuscarinic acetylcholine receptor M5target
ImipraminePotassium voltage-gated channel subfamily D member 2target
ImipraminePotassium voltage-gated channel subfamily D member 3target
ImipramineAlpha-1D adrenergic receptortarget
ImipramineAlpha-1-acid glycoprotein 1carrier
ImipramineSolute carrier family 22 member 2transporter
ImipramineSolute carrier family 22 member 3transporter
ImipramineP-glycoprotein 1transporter
ImipramineSolute carrier family 22 member 4transporter
ImipramineCytochrome P450 3A4enzyme
ImipramineCytochrome P450 2B6enzyme
ImipramineCytochrome P450 2C18enzyme
ImipramineCytochrome P450 2E1enzyme
ImipramineCytochrome P450 3A7enzyme
Imipramine5-hydroxytryptamine receptor 2Ctarget
ImipramineAlpha-1B adrenergic receptortarget
Imipramine5-hydroxytryptamine receptor 7target
ImipramineD(1) dopamine receptortarget
ImipramineDopamine D2 receptortarget
ImipraminePotassium voltage-gated channel subfamily H member 2target
ImipramineSodium-dependent dopamine transportertarget
Imipramine5-hydroxytryptamine receptor 1Atarget
Imipramine5-hydroxytryptamine receptor 6target
ImipraminePotassium voltage-gated channel subfamily H member 1target
ImipramineSerum albumincarrier
ImipramineAlpha-1-acid glycoprotein 2target
DuloxetineSodium-dependent serotonin transportertarget
DuloxetineSodium-dependent dopamine transportertarget
DuloxetineSodium-dependent noradrenaline transportertarget
DuloxetineCytochrome P450 1A2enzyme
DuloxetineCytochrome P450 2D6enzyme
DuloxetineCytochrome P450 2C9enzyme
DuloxetineSerum albumincarrier
Duloxetinealpha1-acid glycoproteincarrier
DuloxetineP-glycoprotein 1transporter
FlutamideAndrogen receptortarget
FlutamideCytochrome P450 1A2enzyme
FlutamideCytochrome P450 3A4enzyme
FlutamideCytochrome P450 1A1enzyme
FlutamideCytochrome P450 1B1enzyme
FlutamideCytochrome P450 2C19enzyme
FlutamideCytochrome P450 3A5enzyme
FlutamideAryl hydrocarbon receptortarget
FlutamideNuclear receptor subfamily 1 group I member 2target
HaloperidolDopamine D2 receptortarget
HaloperidolGlutamate receptor ionotropic, NMDA 2Btarget
HaloperidolDopamine D1 receptortarget
HaloperidolCytochrome P450 1A2enzyme
HaloperidolCytochrome P450 2D6enzyme
Haloperidol5-hydroxytryptamine receptor 2Atarget
HaloperidolDopamine D3 receptortarget
HaloperidolCytochrome P450 3A4enzyme
HaloperidolCytochrome P450 3A5enzyme
HaloperidolCytochrome P450 3A7enzyme
HaloperidolP-glycoprotein 1transporter
HaloperidolCarbonyl reductase [NADPH] 1enzyme
HaloperidolUDP-glucuronosyltransferase 1-9enzyme
HaloperidolCytochrome P450 2C19enzyme
HaloperidolCytochrome P450 2C9enzyme
HaloperidolMelanin-concentrating hormone receptor 1target
HaloperidolSynaptic vesicular amine transportertarget
Haloperidol5-hydroxytryptamine receptor 2Ctarget
HaloperidolSigma non-opioid intracellular receptor 1target
HaloperidolHistamine H1 receptortarget
HaloperidolMuscarinic acetylcholine receptor M3target
HaloperidolAlpha-1A adrenergic receptortarget
HaloperidolAlpha-2A adrenergic receptortarget
HaloperidolAlpha-2B adrenergic receptortarget
HaloperidolAlpha-2C adrenergic receptortarget
Haloperidol5-hydroxytryptamine receptor 1Atarget
Haloperidol5-hydroxytryptamine receptor 6target
Haloperidol5-hydroxytryptamine receptor 7target
HaloperidolCytochrome P450 1A1enzyme
NortriptylineSodium-dependent serotonin transportertarget
NortriptylineSodium-dependent noradrenaline transportertarget
NortriptylineCytochrome P450 1A2enzyme
NortriptylineCytochrome P450 2D6enzyme
NortriptylineSerum albumincarrier
NortriptylineAlpha-1-acid glycoprotein 1carrier
NortriptylineHistamine H1 receptortarget
Nortriptyline5-hydroxytryptamine receptor 2Atarget
NortriptylineAlpha-1A adrenergic receptortarget
Nortriptyline5-hydroxytryptamine receptor 1Atarget
NortriptylineCytochrome P450 3A4enzyme
NortriptylineCytochrome P450 3A5enzyme
NortriptylineAlpha-1D adrenergic receptortarget
NortriptylineCytochrome P450 2C19enzyme
NortriptylineCytochrome P450 2E1enzyme
Nortriptyline5-hydroxytryptamine receptor 2Ctarget
NortriptylineAlpha-1B adrenergic receptortarget
NortriptylineAlpha-2 adrenergic receptorstarget
NortriptylineBeta adrenergic receptortarget
NortriptylineDopamine D2 receptortarget
NortriptylineSigma receptortarget
Nortriptyline5-hydroxytryptamine receptor 1Ctarget
NortriptylineSodium-dependent noradrenaline transportertransporter
NortriptylineMuscarinic acetylcholine receptortarget
NortriptylineP-glycoprotein 1transporter
FluorouracilThymidylate synthasetarget
FluorouracilCytochrome P450 1A2enzyme
FluorouracilThymidine phosphorylaseenzyme
FluorouracilSerum albumincarrier
FluorouracilCytochrome P450 2C9enzyme
FluorouracilDihydropyrimidine dehydrogenase [NADP(+)]enzyme
FluorouracilUridine phosphorylase 1enzyme
FluorouracilUridine phosphorylase 2enzyme
FluorouracilDNAtarget
FluorouracilRNAtarget
FluorouracilCytochrome P450 2A6enzyme
FluorouracilCytochrome P450 2C8enzyme
FluorouracilMethylenetetrahydrofolate reductaseenzyme
FluorouracilThymidylate synthaseenzyme
FluorouracilUridine 5'-monophosphate synthaseenzyme
FluorouracilAmidophosphoribosyltransferaseenzyme
FluorouracilSolute carrier family 22 member 7transporter
FluorouracilEquilibrative nucleoside transporter 1transporter
FluorouracilATP-binding cassette sub-family G member 2transporter
FluorouracilCanalicular multispecific organic anion transporter 2transporter
FluorouracilMultidrug resistance-associated protein 4transporter
FluorouracilMultidrug resistance-associated protein 5transporter
FluorouracilThyroxine-binding globulincarrier
PropranololBeta-1 adrenergic receptortarget
PropranololBeta-2 adrenergic receptortarget
PropranololBeta-3 adrenergic receptortarget
Propranolol5-hydroxytryptamine receptor 1Atarget
Propranolol5-hydroxytryptamine receptor 1Btarget
PropranololCytochrome P450 1A2enzyme
PropranololCytochrome P450 2D6enzyme
PropranololAlpha-1-acid glycoprotein 1carrier
PropranololCytochrome P450 2C19enzyme
PropranololCytochrome P450 3A4enzyme
PropranololCytochrome P450 3A5enzyme
PropranololCytochrome P450 3A7enzyme
PropranololSolute carrier family 22 member 2transporter
PropranololP-glycoprotein 1transporter
PropranololCytochrome P450 1A1enzyme
PropranololAmine oxidase [flavin-containing] Aenzyme
PropranololSerum albumincarrier
EstroneEstrogen receptor alphatarget
EstroneCytochrome P450 1A2enzyme
EstroneCytochrome P450 1A1enzyme
EstroneSerum albumincarrier
EstroneSolute carrier organic anion transporter family member 2B1transporter
EstroneP-glycoprotein 1transporter
EstroneSolute carrier organic anion transporter family member 1A2transporter
EstroneATP-binding cassette sub-family G member 2transporter
EstroneSolute carrier organic anion transporter family member 1B1transporter
EstroneCytochrome P450 3A4enzyme
EstroneCytochrome P450 1B1enzyme
EstroneCytochrome P450 2B6enzyme
EstroneCytochrome P450 2C9enzyme
EstroneCytochrome P450 2E1enzyme
EstroneCytochrome P450 3A5enzyme
EstroneEstrogen receptor betatarget
EstroneAndrogen receptortarget
EstroneCytochrome P450 19A1target
EstroneSex hormone-binding globulintarget
EstroneSolute carrier family 22 member 8transporter
VerapamilATP-sensitive inward rectifier potassium channel 11target
VerapamilVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
VerapamilPotassium voltage-gated channel subfamily H member 2target
VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
VerapamilCytochrome P450 1A2enzyme
VerapamilCytochrome P450 3A5enzyme
VerapamilVoltage-dependent N-type calcium channel subunit alpha-1Btarget
VerapamilVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
VerapamilSodium-dependent serotonin transportertarget
VerapamilCytochrome P450 3A4enzyme
VerapamilP-glycoprotein 1transporter
VerapamilSolute carrier family 22 member 1transporter
VerapamilCanalicular multispecific organic anion transporter 2transporter
VerapamilMultidrug resistance-associated protein 4transporter
VerapamilSolute carrier family 22 member 5transporter
VerapamilSolute carrier organic anion transporter family member 1A2transporter
VerapamilMultidrug resistance-associated protein 7transporter
VerapamilSolute carrier family 22 member 4transporter
VerapamilSolute carrier organic anion transporter family member 1B1transporter
VerapamilCytochrome P450 2C8enzyme
VerapamilCytochrome P450 2C9enzyme
VerapamilCytochrome P450 2B6enzyme
VerapamilCytochrome P450 2C19enzyme
VerapamilCytochrome P450 2D6enzyme
VerapamilAlpha-1A adrenergic receptortarget
VerapamilAlpha-1B adrenergic receptortarget
VerapamilAlpha-1D adrenergic receptortarget
VerapamilSerum albumincarrier
VerapamilAlpha-1-acid glycoprotein 1carrier
VerapamilCytochrome P450 2C18enzyme
VerapamilCytochrome P450 2E1enzyme
VerapamilMultidrug resistance-associated protein 1transporter
VerapamilMultidrug and toxin extrusion protein 1transporter
VerapamilMultidrug and toxin extrusion protein 2transporter
VerapamilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
WarfarinVitamin K epoxide reductase complex subunit 1target
WarfarinCytochrome P450 2C8enzyme
WarfarinCytochrome P450 1A2enzyme
WarfarinCytochrome P450 2C9enzyme
WarfarinAlpha-1-acid glycoprotein 1carrier
WarfarinSerum albumincarrier
WarfarinCytochrome P450 2C19enzyme
WarfarinCytochrome P450 3A4enzyme
WarfarinCytochrome P450 2C18enzyme
WarfarinNuclear receptor subfamily 1 group I member 2target
TizanidineAlpha-2 adrenergic receptorstarget
TizanidineCytochrome P450 1A2enzyme
TizanidineNischarintarget
TizanidineAlpha-1 adrenergic receptorstarget
RiluzoleSodium channel protein type 5 subunit alphatarget
RiluzoleCytochrome P450 1A2enzyme
RiluzoleCystine/glutamate transportertarget
RiluzoleATP-binding cassette sub-family G member 2transporter
RiluzoleCytochrome P450 1A1enzyme
ZileutonArachidonate 5-lipoxygenasetarget
ZileutonCytochrome P450 2C9enzyme
ZileutonCytochrome P450 1A2enzyme
ZileutonCytochrome P450 3A4enzyme
ZileutonProstaglandin G/H synthase 1enzyme
ZileutonUDP-glucuronosyltransferase 1-9enzyme
ZileutonSerum albumincarrier
EstradiolEstrogen receptor alphatarget
EstradiolNuclear receptor subfamily 1 group I member 2target
EstradiolSex hormone-binding globulincarrier
EstradiolEstrogen receptor betatarget
EstradiolCytochrome P450 1A2enzyme
EstradiolUDP-glucuronosyltransferase 1-1enzyme
EstradiolSerum albumincarrier
EstradiolFatty acid-binding protein, intestinalcarrier
EstradiolCytochrome P450 3A4enzyme
EstradiolCytochrome P450 3A5enzyme
EstradiolCytochrome P450 3A7enzyme
EstradiolSolute carrier family 22 member 2transporter
EstradiolSolute carrier family 22 member 3transporter
EstradiolMultidrug resistance-associated protein 7transporter
EstradiolSolute carrier family 22 member 11transporter
EstradiolATP-binding cassette sub-family G member 2transporter
EstradiolSolute carrier organic anion transporter family member 1B1transporter
EstradiolP-glycoprotein 1transporter
EstradiolCytochrome P450 1A1enzyme
EstradiolCytochrome P450 1B1enzyme
EstradiolCytochrome P450 2C19enzyme
EstradiolCytochrome P450 2C8enzyme
EstradiolCytochrome P450 2C9enzyme
EstradiolSolute carrier family 22 member 8transporter
EstradiolSolute carrier organic anion transporter family member 1B3transporter
EstradiolSolute carrier organic anion transporter family member 1C1transporter
EstradiolNeuronal acetylcholine receptor subunit alpha-4target
EstradiolG-protein coupled estrogen receptor 1target
EstradiolATP synthase subunit atarget
EstradiolBeclin-1target
EstradiolUDP-glucuronosyltransferase 2B15enzyme
EstradiolCatechol O-methyltransferaseenzyme
EstradiolUDP-glucuronosyltransferases (UGTs)enzyme
DacarbazineDNA polymerase alpha subunit Btarget
DacarbazineCytochrome P450 1A1enzyme
DacarbazineCytochrome P450 1A2enzyme
DacarbazineCytochrome P450 2E1enzyme
Dacarbazine6-phosphogluconate dehydrogenase, decarboxylatingtarget
DacarbazineDNAtarget
Ondansetron5-hydroxytryptamine receptor 3Atarget
OndansetronCytochrome P450 3A4enzyme
OndansetronCytochrome P450 1A2enzyme
OndansetronCytochrome P450 2D6enzyme
OndansetronCytochrome P450 3A5enzyme
OndansetronCytochrome P450 3A7enzyme
Ondansetron5-hydroxytryptamine receptor 4target
Ondansetron5-hydroxytryptamine receptor 1Atarget
Ondansetron5-hydroxytryptamine receptor 1Btarget
OndansetronMu-type opioid receptortarget
OndansetronCytochrome P450 2C9enzyme
OndansetronCytochrome P450 2E1enzyme
Cyclobenzaprine5-hydroxytryptamine receptor 2Atarget
CyclobenzaprineCytochrome P450 1A2enzyme
CyclobenzaprineCytochrome P450 3A4enzyme
CyclobenzaprineCytochrome P450 2D6enzyme
CyclobenzaprineSerum albumincarrier
CyclobenzaprineUDP-glucuronosyltransferase 1-4enzyme
CyclobenzaprineUDP-glucuronosyltransferase 2B10enzyme
Cyclobenzaprine5-hydroxytryptamine receptor 2Btarget
Cyclobenzaprine5-hydroxytryptamine receptor 2Ctarget
Cyclobenzaprine5-hydroxytryptamine receptor 7target
Cyclobenzaprine5-hydroxytryptamine receptor 6target
CyclobenzaprineSodium-dependent serotonin transportertarget
CyclobenzaprineSodium-dependent noradrenaline transportertarget
CyclobenzaprineToll-like receptor 4target
CyclobenzaprineAldehyde oxidasetarget
RamelteonMelatonin receptor type 1Btarget
RamelteonMelatonin receptor type 1Atarget
RamelteonCytochrome P450 1A2enzyme
RamelteonCytochrome P450 2C19enzyme
RamelteonCytochrome P450 3A4enzyme
RamelteonCytochrome P450 2C9enzyme
Frovatriptan5-hydroxytryptamine receptor 1Dtarget
Frovatriptan5-hydroxytryptamine receptor 1Btarget
FrovatriptanCytochrome P450 1A2enzyme
LevobupivacaineSodium channel protein type 10 subunit alphatarget
LevobupivacaineCytochrome P450 3A4enzyme
LevobupivacaineCytochrome P450 1A2enzyme
CinacalcetExtracellular calcium-sensing receptortarget
CinacalcetCytochrome P450 3A4enzyme
CinacalcetCytochrome P450 2D6enzyme
CinacalcetCytochrome P450 1A2enzyme
PimozideDopamine D2 receptortarget
PimozideCalmodulintarget
PimozidePotassium voltage-gated channel subfamily H member 2target
PimozideCytochrome P450 3A4enzyme
PimozideCytochrome P450 1A2enzyme
PimozideCytochrome P450 3A5enzyme
PimozideCytochrome P450 3A7enzyme
PimozideP-glycoprotein 1transporter
PimozideDopamine D3 receptortarget
PimozideCytochrome P450 2D6enzyme
PropafenoneSodium channel protein type 5 subunit alphatarget
PropafenonePotassium voltage-gated channel subfamily H member 2target
PropafenoneCytochrome P450 1A2enzyme
PropafenoneCytochrome P450 2D6enzyme
PropafenoneCytochrome P450 3A4enzyme
PropafenoneP-glycoprotein 1transporter
PropafenoneBeta-1 adrenergic receptortarget
PropafenoneBeta-2 adrenergic receptortarget
ClomipramineSodium-dependent serotonin transportertarget
ClomipramineSodium-dependent noradrenaline transportertarget
ClomipramineGlutathione S-transferase Ptarget
Clomipramine5-hydroxytryptamine receptor 2Atarget
ClomipramineCytochrome P450 1A2enzyme
ClomipramineCytochrome P450 2D6enzyme
ClomipramineCytochrome P450 2C19enzyme
ClomipramineP-glycoprotein 1transporter
ClomipramineCytochrome P450 3A4enzyme
Clomipramine5-hydroxytryptamine receptor 2Btarget
Clomipramine5-hydroxytryptamine receptor 2Ctarget
ClomipramineSerum albumincarrier
RasagilineApoptosis regulator Bcl-2target
RasagilineAmine oxidase [flavin-containing] Btarget
RasagilineCytochrome P450 1A2enzyme
ChlorzoxazoneCalcium-activated potassium channel subunit alpha-1target
ChlorzoxazoneCytochrome P450 2E1enzyme
ChlorzoxazoneCytochrome P450 1A2enzyme
ChlorzoxazoneCytochrome P450 2A6enzyme
ChlorzoxazoneCytochrome P450 1A1enzyme
ChlorzoxazoneCytochrome P450 2D6enzyme
ChlorzoxazoneCytochrome P450 3A4enzyme
ChlorpromazineDopamine D2 receptortarget
Chlorpromazine5-hydroxytryptamine receptor 2Atarget
ChlorpromazineCytochrome P450 2D6enzyme
ChlorpromazineCholinesteraseenzyme
ChlorpromazineCytochrome P450 1A2enzyme
ChlorpromazineSerum albumincarrier
ChlorpromazineP-glycoprotein 1transporter
ChlorpromazineDopamine D1 receptortarget
Chlorpromazine5-hydroxytryptamine receptor 1Atarget
ChlorpromazineAlpha-1A adrenergic receptortarget
ChlorpromazineAlpha-1B adrenergic receptortarget
ChlorpromazineCytochrome P450 2E1enzyme
ChlorpromazineCytochrome P450 3A4enzyme
ChlorpromazineHistamine H1 receptortarget
ChlorpromazinePotassium voltage-gated channel subfamily H member 2target
ChlorpromazineD(1) dopamine receptortarget
ChlorpromazineDopamine D3 receptortarget
ChlorpromazineDopamine D4 receptortarget
ChlorpromazineDopamine D5 receptortarget
Chlorpromazine5-hydroxytryptamine receptor 2Ctarget
Chlorpromazine5-hydroxytryptamine 2 receptortarget
ChlorpromazineAlpha-1 adrenergic receptorstarget
ChlorpromazineAlpha-2 adrenergic receptorstarget
ChlorpromazineMuscarinic acetylcholine receptor M1target
ChlorpromazineMuscarinic acetylcholine receptor M3target
ChlorpromazineSphingomyelin phosphodiesterasetarget
ChlorpromazineCalmodulintarget
Chlorpromazinealpha1-acid glycoproteintarget
Chlorpromazine5-hydroxytryptamine receptor 6target
Chlorpromazine5-hydroxytryptamine receptor 7target
ChlorpromazineHistamine H4 receptortarget
ChlorpromazineBile salt export pumptransporter
MephenytoinSodium channel protein type 5 subunit alphatarget
MephenytoinCytochrome P450 2B6enzyme
MephenytoinCytochrome P450 2C9enzyme
MephenytoinCytochrome P450 2C19enzyme
MephenytoinCytochrome P450 1A2enzyme
MephenytoinCytochrome P450 2D6enzyme
MephenytoinCytochrome P450 2C8enzyme
MephenytoinNuclear receptor subfamily 1 group I member 2target
MephenytoinThyroxine-binding globulincarrier
DiclofenacProstaglandin G/H synthase 1target
DiclofenacProstaglandin G/H synthase 2target
DiclofenacTransthyretincarrier
DiclofenacCytochrome P450 2C9enzyme
DiclofenacCytochrome P450 2C19enzyme
DiclofenacCytochrome P450 1A2enzyme
DiclofenacCytochrome P450 2C8enzyme
DiclofenacSerum albumincarrier
DiclofenacMultidrug resistance-associated protein 4transporter
DiclofenacMultidrug resistance-associated protein 1transporter
DiclofenacSolute carrier family 22 member 6transporter
DiclofenacSolute carrier family 22 member 8transporter
DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DiclofenacSolute carrier family 22 member 11transporter
DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DiclofenacCytochrome P450 3A4enzyme
DiclofenacCytochrome P450 2B6enzyme
DiclofenacCytochrome P450 2C18enzyme
DiclofenacCytochrome P450 2E1enzyme
DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DiclofenacBile salt export pumptransporter
DiclofenacUDP-glucuronosyltransferase 1-3enzyme
DiclofenacUDP-glucuronosyltransferase 1-9enzyme
DiclofenacUDP-glucuronosyltransferase 2B4enzyme
DiclofenacArachidonate 5-lipoxygenaseenzyme
DiclofenacSodium channel protein type 4 subunit alphatransporter
DiclofenacAcid-sensing ion channel 1transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 2transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 3transporter
DiclofenacPhospholipase A2, membrane associatedenzyme
DiclofenacP-glycoprotein 1transporter
AzelastineHistamine H1 receptortarget
AzelastineCytochrome P450 1A2enzyme
AzelastineCytochrome P450 2D6enzyme
AzelastineCytochrome P450 3A4enzyme
AzelastineCytochrome P450 2C19enzyme
AzelastineCytochrome P450 1A1enzyme
AzelastineCytochrome P450 3A5enzyme
AzelastineCytochrome P450 2C9enzyme
AzelastineCytochrome P450 2C8enzyme
AzelastineP-glycoprotein 1transporter
AzelastineCytochrome P450 2A6enzyme
AzelastineCytochrome P450 2E1enzyme
AzelastineHistamine H2 receptortarget
AzelastinePhospholipase A2target
AzelastineLeukotriene C4 synthasetarget
AzelastineCytochrome P450 2B6enzyme
AcenocoumarolVitamin K epoxide reductase complex subunit 1target
AcenocoumarolCytochrome P450 2C9enzyme
AcenocoumarolCytochrome P450 1A2enzyme
AcenocoumarolSerum albumincarrier
AcenocoumarolAlpha-1-acid glycoprotein 1carrier
AcenocoumarolCytochrome P450 2C19enzyme
AcenocoumarolCytochrome P450 3A4enzyme
AcenocoumarolP-glycoprotein 1transporter
AminophenazoneCytochrome P450 2C19enzyme
AminophenazoneCytochrome P450 1A2enzyme
AminophenazoneCytochrome P450 2C8enzyme
AminophenazoneSolute carrier family 22 member 6transporter
AminophenazoneCytochrome P450 2C9enzyme
AminophenazoneCytochrome P450 2D6enzyme
AminophenazoneCytochrome P450 3A4enzyme
AminophenazoneCytochrome P450 2C18enzyme
AminophenazoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
Palonosetron5-hydroxytryptamine receptor 3Atarget
PalonosetronCytochrome P450 2D6enzyme
PalonosetronCytochrome P450 3A4enzyme
PalonosetronCytochrome P450 1A2enzyme
MelatoninAcetylserotonin O-methyltransferasetarget
MelatoninMelatonin receptor type 1Atarget
MelatoninMelatonin receptor type 1Btarget
MelatoninNuclear receptor ROR-betatarget
MelatoninCalmodulintarget
MelatoninCalreticulintarget
MelatoninRibosyldihydronicotinamide dehydrogenase [quinone]target
MelatoninMyeloperoxidasetarget
MelatoninEstrogen receptor alphatarget
MelatoninEosinophil peroxidasetarget
MelatoninCytochrome P450 1A1enzyme
MelatoninCytochrome P450 1A2enzyme
MelatoninCytochrome P450 2C19enzyme
MelatoninCytochrome P450 2C9enzyme
MelatoninAcetylserotonin O-methyltransferaseenzyme
MelatoninIndoleamine 2,3-dioxygenase 1enzyme
MelatoninMyeloperoxidaseenzyme
MelatoninCytochrome P450 1B1enzyme
MelatoninSolute carrier family 22 member 8transporter
MelatoninCytochrome P450 19A1enzyme
ImatinibPlatelet-derived growth factor receptor betatarget
ImatinibTyrosine-protein kinase ABL1target
ImatinibMast/stem cell growth factor receptor Kittarget
ImatinibRET proto-oncogenetarget
ImatinibHigh affinity nerve growth factor receptortarget
ImatinibMacrophage colony-stimulating factor 1 receptortarget
ImatinibPlatelet-derived growth factor receptor alphatarget
ImatinibEpithelial discoidin domain-containing receptor 1target
ImatinibCytochrome P450 3A4enzyme
ImatinibBreakpoint cluster region proteintarget
ImatinibCytochrome P450 1A2enzyme
ImatinibCytochrome P450 2D6enzyme
ImatinibCytochrome P450 2C9enzyme
ImatinibCytochrome P450 2C19enzyme
ImatinibCytochrome P450 3A5enzyme
ImatinibCytochrome P450 3A7enzyme
ImatinibSolute carrier family 22 member 1transporter
ImatinibP-glycoprotein 1transporter
ImatinibSolute carrier family 22 member 2transporter
ImatinibATP-binding cassette sub-family G member 2transporter
ImatinibATP-binding cassette sub-family A member 3transporter
ImatinibProstaglandin G/H synthase 1enzyme
ImatinibSerum albumincarrier
ImatinibAlpha-1-acid glycoprotein 1carrier
ImatinibBile salt export pumptransporter
ImatinibCytochrome P450 2C8enzyme
QuininePlatelet glycoprotein IXtarget
QuinineIntermediate conductance calcium-activated potassium channel protein 4target
QuinineCytochrome P450 3A4enzyme
QuinineCytochrome P450 3A5enzyme
QuinineCytochrome P450 1A1enzyme
QuinineCytochrome P450 2D6enzyme
QuinineCytochrome P450 1A2enzyme
QuinineCytochrome P450 2C8enzyme
QuinineCytochrome P450 2C9enzyme
QuinineCytochrome P450 2C19enzyme
QuinineCytochrome P450 2E1enzyme
QuinineCytochrome P450 3A7enzyme
QuinineSolute carrier family 22 member 2transporter
QuinineSolute carrier family 22 member 1transporter
QuinineSolute carrier family 22 member 5transporter
QuinineP-glycoprotein 1transporter
QuinineSolute carrier organic anion transporter family member 1A2transporter
QuinineSolute carrier family 22 member 4transporter
QuinineFe(II)-protoporphyrin IXtarget
QuinineSolute carrier organic anion transporter family member 1B1transporter
DoxepinSodium-dependent serotonin transportertarget
DoxepinSodium-dependent noradrenaline transportertarget
DoxepinHistamine H1 receptortarget
DoxepinHistamine H2 receptortarget
DoxepinCytochrome P450 2D6enzyme
DoxepinMuscarinic acetylcholine receptor M1target
DoxepinMuscarinic acetylcholine receptor M2target
DoxepinMuscarinic acetylcholine receptor M3target
DoxepinMuscarinic acetylcholine receptor M4target
DoxepinMuscarinic acetylcholine receptor M5target
DoxepinAlpha-1A adrenergic receptortarget
Doxepin5-hydroxytryptamine receptor 1Atarget
Doxepin5-hydroxytryptamine receptor 2Atarget
DoxepinCytochrome P450 2C19enzyme
DoxepinCytochrome P450 2C9enzyme
DoxepinCytochrome P450 1A2enzyme
DoxepinP-glycoprotein 1transporter
Doxepin5-hydroxytryptamine receptor 2Btarget
Doxepin5-hydroxytryptamine receptor 2Ctarget
DoxepinAlpha-1B adrenergic receptortarget
DoxepinAlpha-1D adrenergic receptortarget
DoxepinCytochrome P450 3A4enzyme
Doxepin5-hydroxytryptamine receptor 6target
DoxepinHistamine H4 receptortarget
DoxepinPotassium voltage-gated channel subfamily H member 2target
DoxepinSerum albumincarrier
DoxepinAlpha-1-acid glycoprotein 1carrier
CarbamazepineVoltage-gated sodium channel alpha subunittarget
CarbamazepineCytochrome P450 2C8enzyme
CarbamazepineCytochrome P450 2B6enzyme
CarbamazepineCytochrome P450 3A4enzyme
CarbamazepineCytochrome P450 1A2enzyme
CarbamazepineCytochrome P450 2C19enzyme
CarbamazepineCytochrome P450 2C9enzyme
CarbamazepineP-glycoprotein 1transporter
CarbamazepineCytochrome P450 3A5enzyme
CarbamazepineUDP-glucuronosyltransferase 2B7enzyme
CarbamazepineRalA-binding protein 1transporter
CarbamazepineCanalicular multispecific organic anion transporter 1transporter
CarbamazepineNeuronal acetylcholine receptor subunit alpha-4target
CarbamazepineNuclear receptor subfamily 1 group I member 2target
CarbamazepineUDP-glucuronosyltransferase 1-1enzyme
CarbamazepineUDP-glucuronosyltransferase 1-6enzyme
CarbamazepineUDP-glucuronosyltransferase 1-7enzyme
ZolpidemGamma-aminobutyric acid receptor subunit alpha-1target
ZolpidemCytochrome P450 3A4enzyme
ZolpidemCytochrome P450 1A2enzyme
ZolpidemGamma-aminobutyric acid receptor subunit alpha-2target
ZolpidemGamma-aminobutyric acid receptor subunit alpha-3target
ZolpidemCytochrome P450 2C9enzyme
ZolpidemCytochrome P450 2C19enzyme
ZolpidemCytochrome P450 2D6enzyme
ZolpidemGamma-aminobutyric acid receptor subunit gamma-2target
FluoxetineSodium-dependent serotonin transportertarget
FluoxetineCytochrome P450 2C9enzyme
FluoxetineCytochrome P450 2D6enzyme
FluoxetineCYP2B proteinenzyme
FluoxetineCytochrome P450 1A2enzyme
FluoxetineCytochrome P450 3A4enzyme
FluoxetineCytochrome P450 2C19enzyme
FluoxetineP-glycoprotein 1transporter
FluoxetineCytochrome P450 2B6enzyme
FluoxetineCytochrome P450 3A5enzyme
FluoxetineSerum albumincarrier
FluoxetineAlpha-1-acid glycoprotein 1carrier
FluoxetinePotassium voltage-gated channel subfamily H member 2target
Fluoxetine5-hydroxytryptamine receptor 2Ctarget
FluoxetineCyclin-dependent kinases regulatory subunit 1target
FluoxetineNeuronal acetylcholine receptor subunit alpha-2target
FluoxetineNeuronal acetylcholine receptor subunit alpha-3target
FluoxetineNeuronal acetylcholine receptor subunit beta-4target
AntipyrineCytochrome P450 2C8enzyme
AntipyrineCytochrome P450 2C9enzyme
AntipyrineCytochrome P450 1A2enzyme
AntipyrineCytochrome P450 2C19enzyme
AntipyrineCytochrome P450 3A4enzyme
AntipyrineSolute carrier family 22 member 6transporter
AntipyrineCytochrome P450 2A6enzyme
AntipyrineCytochrome P450 2B6enzyme
AntipyrineCytochrome P450 2C18enzyme
AntipyrineCytochrome P450 2D6enzyme
AntipyrineCytochrome P450 2E1enzyme
AntipyrineProstaglandin G/H synthase 2target
AntipyrineProstaglandin G/H synthase 1target
TerbinafineSqualene monooxygenasetarget
TerbinafineCytochrome P450 2D6enzyme
TerbinafineCytochrome P450 2C9enzyme
TerbinafineCytochrome P450 1A2enzyme
TerbinafineCytochrome P450 3A4enzyme
TerbinafineCytochrome P450 2C8enzyme
TerbinafineCytochrome P450 2C19enzyme
TerbinafineProstaglandin G/H synthase 1enzyme
TerbinafineSerum albumincarrier
Terbinafinealpha1-acid glycoproteincarrier
TerbinafineABC multidrug transporter MDR2transporter
TerbinafineSqualene monooxygenasetarget
CinnarizineHistamine H1 receptortarget
CinnarizineDopamine D2 receptortarget
CinnarizineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
CinnarizineCytochrome P450 2D6enzyme
CinnarizineCytochrome P450 2B6enzyme
CinnarizineCytochrome P450 2C9enzyme
CinnarizineCytochrome P450 1A1enzyme
CinnarizineCytochrome P450 1A2enzyme
CinnarizineCytochrome P450 2A6enzyme
CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Starget
CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
CinnarizineVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
CinnarizineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
CinnarizineD(1) dopamine receptortarget
CinnarizineMuscarinic acetylcholine receptortarget
CinnarizineCytochrome P450 3A4enzyme
FlunarizineHistamine H1 receptortarget
FlunarizineVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
FlunarizineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
FlunarizineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
FlunarizineCalmodulintarget
FlunarizineCytochrome P450 2D6enzyme
FlunarizineCytochrome P450 2C9enzyme
FlunarizineCytochrome P450 1A1enzyme
FlunarizineCytochrome P450 1A2enzyme
FlunarizineCytochrome P450 2A6enzyme
FlunarizineCytochrome P450 3A4enzyme
NaproxenProstaglandin G/H synthase 1target
NaproxenProstaglandin G/H synthase 2target
NaproxenSerum albumincarrier
NaproxenCytochrome P450 2C9enzyme
NaproxenCytochrome P450 1A2enzyme
NaproxenSolute carrier organic anion transporter family member 1A2transporter
NaproxenSolute carrier family 22 member 6transporter
NaproxenCytochrome P450 2C8enzyme
NaproxenUDP-glucuronosyltransferase 2B7enzyme
NaproxenPeptostreptococcal albumin-binding proteintarget
NaproxenBile salt export pumptransporter
NaproxenP-glycoprotein 1transporter
NaproxenUDP-glucuronosyltransferase 1-3enzyme
NaproxenUDP-glucuronosyltransferase 1-6enzyme
NaproxenUDP-glucuronosyltransferase 1-7enzyme
NaproxenUDP-glucuronosyltransferase 1-8enzyme
NaproxenUDP-glucuronosyltransferase 1-9enzyme
NaproxenUDP-glucuronosyltransferase 1-10enzyme
NaproxenSolute carrier family 22 member 8transporter
PhenacetinProstaglandin G/H synthase 1target
PhenacetinCytochrome P450 1A2enzyme
PhenacetinCytochrome P450 2D6enzyme
PhenacetinSolute carrier family 22 member 6transporter
PhenacetinCytochrome P450 1A1enzyme
PhenacetinCytochrome P450 2A13enzyme
PhenacetinCytochrome P450 2A6enzyme
PhenacetinCytochrome P450 2C19enzyme
PhenacetinCytochrome P450 2C9enzyme
PhenacetinCytochrome P450 2E1enzyme
PhenacetinCytochrome P450 3A4enzyme
AminophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
AminophyllineAdenosine receptor A3target
AminophyllineAdenosine receptor A1target
AminophyllineCytochrome P450 1A2enzyme
AminophyllineCytochrome P450 2E1enzyme
AminophyllineCytochrome P450 3A4enzyme
AminophyllineHistone deacetylase 2target
Asenapine5-hydroxytryptamine receptor 1Atarget
Asenapine5-hydroxytryptamine receptor 1Btarget
Asenapine5-hydroxytryptamine receptor 2Atarget
Asenapine5-hydroxytryptamine receptor 2Btarget
Asenapine5-hydroxytryptamine receptor 2Ctarget
Asenapine5-hydroxytryptamine receptor 6target
Asenapine5-hydroxytryptamine receptor 7target
AsenapineAlpha-2A adrenergic receptortarget
AsenapineAlpha-2B adrenergic receptortarget
AsenapineAlpha-2C adrenergic receptortarget
AsenapineAlpha-1A adrenergic receptortarget
AsenapineDopamine D1 receptortarget
AsenapineDopamine D2 receptortarget
AsenapineDopamine D3 receptortarget
AsenapineDopamine D4 receptortarget
AsenapineHistamine H1 receptortarget
AsenapineHistamine H2 receptortarget
AsenapineCytochrome P450 1A2enzyme
AsenapineCytochrome P450 2D6enzyme
Asenapine5-hydroxytryptamine receptor 5Atarget
AsenapineUDP-glucuronosyltransferase 1-4enzyme
AsenapineCytochrome P450 3A4enzyme
AsenapineBeta-1 adrenergic receptortarget
AsenapineBeta-2 adrenergic receptortarget
AsenapineSerum albumincarrier
Asenapinealpha1-acid glycoproteincarrier
BetaxololBeta-1 adrenergic receptortarget
BetaxololBeta-2 adrenergic receptortarget
BetaxololCytochrome P450 1A2enzyme
BetaxololCytochrome P450 2D6enzyme
Estrone sulfateCytochrome P450 1A2enzyme
Estrone sulfateCytochrome P450 3A4enzyme
Estrone sulfateEstrogen receptor alphatarget
Estrone sulfateEstrogen receptor betatarget
Estrone sulfateSex hormone-binding globulincarrier
Estrone sulfateSerum albumincarrier
Estrone sulfateCytochrome P450 2C9enzyme
Estrone sulfateMultidrug and toxin extrusion protein 1transporter
Estrone sulfateMultidrug and toxin extrusion protein 2transporter
GuanabenzAlpha-2A adrenergic receptortarget
GuanabenzCytochrome P450 1A2enzyme
GuanabenzAlpha-2B adrenergic receptortarget
ThiothixeneCytochrome P450 1A2enzyme
ThiothixeneCytochrome P450 2D6enzyme
ThiothixeneDopamine D2 receptortarget
ThiothixeneDopamine D1 receptortarget
Thiothixene5-hydroxytryptamine receptor 2Atarget
ThiothixeneSolute carrier family 22 member 1transporter
ThiothixeneSerum albumincarrier
TrifluoperazineDopamine D2 receptortarget
TrifluoperazineAlpha-1A adrenergic receptortarget
TrifluoperazineNeuron-specific vesicular protein calcyontarget
TrifluoperazineXanthine dehydrogenase/oxidaseenzyme
TrifluoperazineUDP-glucuronosyltransferase 1-4enzyme
TrifluoperazineCytochrome P450 1A2enzyme
TrifluoperazineP-glycoprotein 1transporter
TrifluoperazineCalmodulintarget
TrifluoperazineTroponin C, slow skeletal and cardiac musclestarget
TrifluoperazineProtein S100-A4target
PromazineDopamine D2 receptortarget
Promazine5-hydroxytryptamine receptor 2Atarget
Promazine5-hydroxytryptamine receptor 2Ctarget
PromazineAlpha-1A adrenergic receptortarget
PromazineMuscarinic acetylcholine receptor M1target
PromazineHistamine H1 receptortarget
PromazineCytochrome P450 2C19enzyme
PromazineCytochrome P450 1A2enzyme
PromazineCytochrome P450 3A4enzyme
PromazineCytochrome P450 2C9enzyme
PromazineCytochrome P450 2D6enzyme
CarvedilolAlpha-1A adrenergic receptortarget
CarvedilolBeta-1 adrenergic receptortarget
CarvedilolNADH dehydrogenase [ubiquinone] 1 subunit C2target
CarvedilolBeta-2 adrenergic receptortarget
CarvedilolVascular endothelial growth factor Atarget
CarvedilolNatriuretic peptides Btarget
CarvedilolGap junction alpha-1 proteintarget
CarvedilolPotassium voltage-gated channel subfamily H member 2target
CarvedilolVascular cell adhesion protein 1target
CarvedilolCytochrome P450 2C9enzyme
CarvedilolCytochrome P450 2D6enzyme
CarvedilolXanthine dehydrogenase/oxidaseenzyme
CarvedilolP-glycoprotein 1transporter
CarvedilolCytochrome P450 1A2enzyme
CarvedilolCytochrome P450 3A4enzyme
CarvedilolCytochrome P450 1A1enzyme
CarvedilolCytochrome P450 2E1enzyme
CarvedilolAlpha-1D adrenergic receptortarget
CarvedilolAlpha-1B adrenergic receptortarget
CarvedilolAlpha-2C adrenergic receptortarget
CarvedilolAlpha-2B adrenergic receptortarget
CarvedilolAlpha-2A adrenergic receptortarget
CarvedilolE-selectintarget
CarvedilolHypoxia-inducible factor 1-alphatarget
CarvedilolInward rectifier potassium channel 4target
CarvedilolUDP-glucuronosyltransferase 1-1enzyme
CarvedilolSerum albumincarrier
CarvedilolUDP-glucuronosyltransferase 2B4enzyme
CarvedilolUDP-glucuronosyltransferase 2B7enzyme
CarvedilolInward rectifier potassium channel 2target
CarvedilolAlpha-1 adrenergic receptorstarget
GenisteinEstrogen receptor betatarget
GenisteinDNA topoisomerase 2-alphatarget
GenisteinProtein-tyrosine kinase 2-betatarget
GenisteinP-glycoprotein 1transporter
GenisteinMultidrug resistance-associated protein 1transporter
GenisteinATP-binding cassette sub-family G member 2transporter
GenisteinCytochrome P450 1A2enzyme
GenisteinNuclear receptor coactivator 1target
GenisteinEstrogen receptor alphatarget
GenisteinNuclear receptor coactivator 2target
GenisteinTransthyretincarrier
GenisteinSteroid hormone receptor ERR2target
GenisteinSteroid hormone receptor ERR1target
GenisteinNuclear receptor subfamily 1 group I member 2target
GenisteinRAC-alpha serine/threonine-protein kinasetarget
GenisteinG-protein coupled estrogen receptor 1target
GenisteinCytochrome P450 1B1target
GenisteinSex hormone-binding globulintarget
GenisteinCytochrome P450 1A1enzyme
GenisteinSolute carrier organic anion transporter family member 1B1transporter
GenisteinSolute carrier organic anion transporter family member 2B1transporter
GenisteinCytochrome P450 2C8enzyme
GenisteinCytochrome P450 2C9enzyme
GenisteinCytochrome P450 3A1enzyme
GenisteinCytochrome P450 3A2enzyme
GenisteinCytochrome P450 3A4enzyme
ResveratrolTransthyretincarrier
ResveratrolRibosyldihydronicotinamide dehydrogenase [quinone]target
ResveratrolProstaglandin G/H synthase 1target
ResveratrolCasein kinase II subunit alphatarget
ResveratrolProstaglandin G/H synthase 2target
ResveratrolNAD-dependent protein deacetylase sirtuin-1target
ResveratrolCytochrome P450 1A1enzyme
ResveratrolCytochrome P450 3A4enzyme
ResveratrolCytochrome P450 1A2enzyme
ResveratrolCytochrome P450 1B1enzyme
ResveratrolArachidonate 15-lipoxygenasetarget
ResveratrolArachidonate 5-lipoxygenasetarget
ResveratrolAryl hydrocarbon receptortarget
ResveratrolPhosphatidylinositol 4-kinase type 2-betatarget
ResveratrolIntegrin alpha-5target
ResveratrolIntegrin beta-3target
ResveratrolSerum albumincarrier
ResveratrolAmyloid beta A4 proteintarget
ResveratrolAlpha-synucleintarget
ResveratrolEstrogen receptor alphatarget
ResveratrolMelatonin receptor type 1Atarget
ResveratrolMelatonin receptor type 1Btarget
ResveratrolC-type lectin domain family 14 member Atarget
ResveratrolNuclear receptor subfamily 1 group I member 2target
ResveratrolNuclear receptor subfamily 1 group I member 3target
ResveratrolSolute carrier family 2, facilitated glucose transporter member 1target
ResveratrolCarbonyl reductase [NADPH] 1target
ResveratrolPeroxisome proliferator-activated receptor alphatarget
ResveratrolPeroxisome proliferator-activated receptor gammatarget
ResveratrolRAC-alpha serine/threonine-protein kinasetarget
ResveratrolFar upstream element-binding protein 2target
ResveratrolTyrosine--tRNA ligase, cytoplasmictarget
AlbendazoleTubulin alpha-1A chaintarget
AlbendazoleTubulin beta-4B chaintarget
AlbendazoleCytochrome P450 3A4enzyme
AlbendazoleFumarate reductase flavoprotein subunittarget
AlbendazoleCytochrome P450 1A1enzyme
AlbendazoleCytochrome P450 1A2enzyme
AlbendazoleTubulin beta-2 chaintarget
AlbendazoleCytochrome P450 2C19enzyme
AlbendazoleP-glycoprotein 1transporter
BromazepamCytochrome P450 1A2enzyme
BromazepamCytochrome P450 2C19enzyme
BromazepamCytochrome P450 2E1enzyme
BromazepamGABA(A) Receptortarget
BromazepamGABA(A) Receptor Benzodiazepine Binding Sitetarget
DesipramineMuscarinic acetylcholine receptor M1target
DesipramineSodium-dependent noradrenaline transportertarget
DesipramineBeta-2 adrenergic receptortarget
DesipramineMuscarinic acetylcholine receptor M2target
DesipramineSodium-dependent serotonin transportertarget
DesipramineHistamine H1 receptortarget
DesipramineBeta-1 adrenergic receptortarget
DesipramineCytochrome P450 2D6enzyme
DesipramineMuscarinic acetylcholine receptor M3target
DesipramineMuscarinic acetylcholine receptor M4target
DesipramineMuscarinic acetylcholine receptor M5target
DesipramineAlpha-1 adrenergic receptorstarget
Desipramine5-hydroxytryptamine receptor 2Atarget
DesipramineAlpha-1-acid glycoprotein 1carrier
DesipramineCytochrome P450 2B6enzyme
DesipramineCytochrome P450 3A4enzyme
DesipramineSolute carrier family 22 member 2transporter
DesipramineSolute carrier family 22 member 1transporter
DesipramineSolute carrier family 22 member 3transporter
DesipramineSolute carrier family 22 member 5transporter
DesipramineP-glycoprotein 1transporter
DesipramineSolute carrier family 22 member 4transporter
DesipramineCytochrome P450 1A2enzyme
DesipramineCytochrome P450 2E1enzyme
DesipramineSphingomyelin phosphodiesterasetarget
Desipramine5-hydroxytryptamine receptor 1Atarget
Desipramine5-hydroxytryptamine receptor 2Ctarget
DesipramineDopamine D2 receptortarget
DesipramineAlpha-2 adrenergic receptorstarget
DexfenfluramineSodium-dependent serotonin transportertarget
Dexfenfluramine5-hydroxytryptamine receptor 2Ctarget
DexfenfluramineCytochrome P450 2D6enzyme
DexfenfluramineCytochrome P450 1A2enzyme
DexfenfluramineCytochrome P450 2E1enzyme
DomperidoneDopamine D2 receptortarget
DomperidoneCytochrome P450 3A4enzyme
DomperidoneCytochrome P450 3A5enzyme
DomperidoneCytochrome P450 3A7enzyme
DomperidoneP-glycoprotein 1transporter
DomperidoneCytochrome P450 1A2enzyme
DomperidoneCytochrome P450 2B6enzyme
DomperidoneCytochrome P450 2C8enzyme
DomperidoneCytochrome P450 2D6enzyme
DomperidoneDopamine D3 receptortarget
EthanolGamma-aminobutyric acid receptor subunit alpha-1target
EthanolGlutamate receptor ionotropic, NMDA 3Atarget
EthanolGlycine receptor subunit alpha-1target
EthanolGlycine receptor subunit alpha-2target
EthanolCytochrome P450 2E1enzyme
EthanolCytochrome P450 1A1enzyme
EthanolCytochrome P450 1A2enzyme
EthanolCytochrome P450 2B6enzyme
EthanolCytochrome P450 2C19enzyme
EthanolCytochrome P450 2C9enzyme
EthanolCytochrome P450 3A4enzyme
EthanolCytochrome P450 4A11enzyme
EthanolAlcohol dehydrogenase 1Aenzyme
EthanolAlcohol dehydrogenase 1Benzyme
EthanolAlcohol dehydrogenase 1Cenzyme
EthanolAlcohol dehydrogenase class-3enzyme
EthanolVoltage-dependent L-type calcium channel subunit beta-1target
Ethanol5-hydroxytryptamine receptor 3Atarget
EthanolAlcohol dehydrogenase 4enzyme
EthanolGamma-aminobutyric acid receptor subunit alpha-2target
EthanolNeuronal acetylcholine receptor subunit alpha-10target
EthanolVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
EthanolGamma-aminobutyric acid receptor subunit alpha-5target
EthanolGamma-aminobutyric acid receptor subunit alpha-4target
EthanolAlcohol dehydrogenase class 4 mu/sigma chainenzyme
EthanolGamma-aminobutyric acid receptor subunit alpha-3target
EthanolGlutamate receptor 1target
EthanolVoltage-dependent calcium channel gamma-1 subunittarget
EthanolNeuronal acetylcholine receptor subunit alpha-2target
EthanolGamma-aminobutyric acid receptor subunit alpha-6target
EthanolGlutamate receptor 2target
EthanolGlutamate receptor 4target
EthanolGlutamate receptor 3target
EthanolNeuronal acetylcholine receptor subunit alpha-4target
EthanolNeuronal acetylcholine receptor subunit beta-2target
EthanolG protein-activated inward rectifier potassium channel 1target
EthanolG protein-activated inward rectifier potassium channel 2target
EthanolVascular cell adhesion protein 1target
EthanolEquilibrative nucleoside transporter 1target
EthanolG protein-activated inward rectifier potassium channel 4target
EthanolNeuronal acetylcholine receptor subunit alpha-7target
EthanolNeuronal acetylcholine receptor subunit alpha-9target
EthanolGamma-aminobutyric acid receptor subunit beta-1target
EthanolGamma-aminobutyric acid receptor subunit beta-3target
EthanolGamma-aminobutyric acid receptor subunit beta-2target
EthanolVoltage-dependent L-type calcium channel subunit alpha-1Starget
EthanolVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
EthanolAlcohol dehydrogenase 6enzyme
EthanolNeuronal acetylcholine receptor subunit beta-4target
EthanolNeuronal acetylcholine receptor subunit alpha-3target
EthanolNeuronal acetylcholine receptor subunit alpha-5target
EthanolNeuronal acetylcholine receptor subunit alpha-6target
EthanolNeuronal acetylcholine receptor subunit beta-3target
EthanolGamma-aminobutyric acid receptor subunit gamma-1target
EthanolGamma-aminobutyric acid receptor subunit gamma-3target
EthanolGamma-aminobutyric acid receptor subunit epsilontarget
EthanolGamma-aminobutyric acid receptor subunit pitarget
EthanolGamma-aminobutyric acid receptor subunit thetatarget
EthanolGamma-aminobutyric acid receptor subunit deltatarget
EthanolAlcohol dehydrogenase [NADP(+)]enzyme
EthanolEquilibrative nucleoside transporter 2target
Ethanol5-hydroxytryptamine receptor 3Etarget
Ethanol5-hydroxytryptamine receptor 3Btarget
Ethanol5-hydroxytryptamine receptor 3Dtarget
Ethanol5-hydroxytryptamine receptor 3Ctarget
EthanolVoltage-dependent calcium channel gamma-2 subunittarget
EthanolG protein-activated inward rectifier potassium channel 3target
EthanolNeural cell adhesion molecule L1target
EtoposideDNA topoisomerase 2-alphatarget
EtoposideCytochrome P450 3A4enzyme
EtoposideCanalicular multispecific organic anion transporter 2transporter
EtoposideMultidrug resistance-associated protein 6transporter
EtoposideP-glycoprotein 1transporter
EtoposideMultidrug resistance-associated protein 1transporter
EtoposideMultidrug resistance-associated protein 7transporter
EtoposideCanalicular multispecific organic anion transporter 1transporter
EtoposideATP-binding cassette sub-family G member 2transporter
EtoposideCytochrome P450 1A2enzyme
EtoposideCytochrome P450 2E1enzyme
EtoposideCytochrome P450 3A5enzyme
EtoposideUDP-glucuronosyltransferase 1-1enzyme
EtoposideDNA topoisomerase 2-betatarget
EtoposideGlutathione S-transferase theta-1enzyme
EtoposideGlutathione S-transferase Penzyme
EtoposideProstaglandin G/H synthase 2enzyme
EtoposideProstaglandin G/H synthase 1enzyme
LumiracoxibProstaglandin G/H synthase 2target
LumiracoxibProstaglandin G/H synthase 1target
LumiracoxibCytochrome P450 2C9enzyme
LumiracoxibCytochrome P450 2C19enzyme
LumiracoxibUDP-glucuronosyltransferase 1-9enzyme
LumiracoxibCytochrome P450 1A2enzyme
MalathionCholinesterasetarget
MalathionCytochrome P450 1A2enzyme
MalathionCytochrome P450 2B6enzyme
MaprotilineHistamine H1 receptortarget
MaprotilineSodium-dependent noradrenaline transportertarget
MaprotilineAlpha-1 adrenergic receptorstarget
MaprotilineCytochrome P450 2D6enzyme
MaprotilineAlpha-1-acid glycoprotein 1carrier
MaprotilineMuscarinic acetylcholine receptor M1target
MaprotilineMuscarinic acetylcholine receptor M2target
MaprotilineMuscarinic acetylcholine receptor M3target
MaprotilineMuscarinic acetylcholine receptor M4target
MaprotilineMuscarinic acetylcholine receptor M5target
MaprotilineCytochrome P450 1A2enzyme
Maprotiline5-hydroxytryptamine receptor 2Atarget
Maprotiline5-hydroxytryptamine receptor 2Ctarget
Maprotiline5-hydroxytryptamine receptor 7target
MaprotilineDopamine D2 receptortarget
MaprotilineAlpha-2 adrenergic receptorstarget
MethadoneNMDA receptortarget
MethadoneMu-type opioid receptortarget
MethadoneCytochrome P450 2B6enzyme
MethadoneCytochrome P450 3A4enzyme
MethadoneCytochrome P450 2C19enzyme
MethadoneDelta-type opioid receptortarget
MethadoneCytochrome P450 3A7enzyme
MethadoneCytochrome P450 2D6enzyme
MethadoneP-glycoprotein 1transporter
MethadoneCytochrome P450 2C8enzyme
MethadoneCytochrome P450 19A1enzyme
MethadoneCytochrome P450 1A2enzyme
MethadoneCytochrome P450 2C18enzyme
MethadoneCytochrome P450 2C9enzyme
Methadone5-hydroxytryptamine receptor 3Atarget
MethadoneAlpha-1-acid glycoprotein 1carrier
MethadoneSerum albumincarrier
MethadoneNeuronal acetylcholine receptor subunit alpha-7target
MethadoneNeuronal acetylcholine receptor subunit alpha-3target
MethadoneNeuronal acetylcholine receptor subunit alpha-4target
MethadoneNeuronal acetylcholine receptor subunit beta-2target
MethoxyfluraneCalcium-transporting ATPase type 2C member 1target
MethoxyfluraneNADH-ubiquinone oxidoreductase chain 1target
MethoxyfluraneGamma-aminobutyric acid receptor subunit alpha-1target
MethoxyfluranePotassium voltage-gated channel subfamily A member 1target
MethoxyfluraneGlutamate receptor 1target
MethoxyfluraneGlycine receptor subunit alpha-1target
MethoxyfluraneCytochrome P450 2E1enzyme
MethoxyfluraneCytochrome P450 1A2enzyme
MethoxyfluraneCytochrome P450 2A6enzyme
MethoxyfluraneCytochrome P450 2B6enzyme
MethoxyfluraneCytochrome P450 2C9enzyme
MethoxyfluraneCytochrome P450 2D6enzyme
MethoxyfluraneCytochrome P450 3A4enzyme
MethoxyfluraneGABA(A) Receptortarget
MianserinHistamine H1 receptortarget
MianserinAlpha-2A adrenergic receptortarget
Mianserin5-hydroxytryptamine receptor 2Atarget
Mianserin5-hydroxytryptamine receptor 2Ctarget
MianserinCytochrome P450 2D6enzyme
MianserinSodium-dependent serotonin transportertarget
MianserinCytochrome P450 3A4enzyme
MianserinCytochrome P450 1A2enzyme
MianserinCytochrome P450 2B6enzyme
MianserinSodium-dependent noradrenaline transportertarget
MianserinHistamine H4 receptortarget
Mianserin5-hydroxytryptamine receptor 1Atarget
MianserinAlpha-2C adrenergic receptortarget
Mianserin5-hydroxytryptamine receptor 2Btarget
Mianserin5-hydroxytryptamine receptor 1Ftarget
MianserinAlpha-2B adrenergic receptortarget
MianserinDopamine D3 receptortarget
MianserinKappa-type opioid receptortarget
MianserinSodium-dependent dopamine transportertarget
Mianserin5-hydroxytryptamine receptor 7target
MianserinDopamine D2 receptortarget
Mianserin5-hydroxytryptamine receptor 6target
MianserinAlpha-1 adrenergic receptorstarget
MianserinD(1) dopamine receptortarget
Pentoxifylline5'-nucleotidasetarget
PentoxifyllineAdenosine receptor A1target
PentoxifyllineAdenosine receptor A2atarget
PentoxifyllineCytochrome P450 1A2enzyme
PentoxifyllinePhosphodiesterase enzymestarget
PerphenazineDopamine D1 receptortarget
PerphenazineDopamine D2 receptortarget
PerphenazineCalmodulintarget
PerphenazineCytochrome P450 2D6enzyme
PerphenazineCytochrome P450 1A2enzyme
PerphenazineCytochrome P450 2C18enzyme
PerphenazineCytochrome P450 2C19enzyme
PerphenazineCytochrome P450 2C8enzyme
PerphenazineCytochrome P450 2C9enzyme
PerphenazineCytochrome P450 3A4enzyme
SelegilineAmine oxidase [flavin-containing] Btarget
SelegilineCytochrome P450 2B6enzyme
SelegilineAmine oxidase [flavin-containing] Atarget
SelegilineCytochrome P450 2A6enzyme
SelegilineCytochrome P450 3A4enzyme
SelegilineP-glycoprotein 1transporter
SelegilineCytochrome P450 1A2enzyme
SelegilineCytochrome P450 2C19enzyme
SelegilineCytochrome P450 2C8enzyme
SelegilineCytochrome P450 2C9enzyme
SelegilineCytochrome P450 2D6enzyme
SelegilineCytochrome P450 2E1enzyme
TheobromineCytochrome P450 1A2enzyme
TheobromineCytochrome P450 2E1enzyme
TheobromineAdenosine receptor A1target
TheobromineAdenosine receptor A2atarget
TheobrominecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
TolperisoneCytochrome P450 1A2enzyme
ErlotinibEpidermal growth factor receptortarget
ErlotinibCytochrome P450 3A4enzyme
ErlotinibATP-binding cassette sub-family G member 2transporter
ErlotinibP-glycoprotein 1transporter
ErlotinibNuclear receptor subfamily 1 group I member 2target
ErlotinibCytochrome P450 3A5enzyme
ErlotinibCytochrome P450 1A1enzyme
ErlotinibCytochrome P450 1A2enzyme
ErlotinibCytochrome P450 1B1enzyme
ErlotinibCytochrome P450 2D6enzyme
ErlotinibCytochrome P450 2C8enzyme
ErlotinibUDP-glucuronosyltransferase 1-1enzyme
ErlotinibSerum albumincarrier
ErlotinibAlpha-1-acid glycoprotein 1carrier
ErlotinibSolute carrier organic anion transporter family member 2B1transporter
CilostazolcGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
CilostazolCytochrome P450 2C19enzyme
CilostazolCytochrome P450 3A4enzyme
CilostazolCytochrome P450 3A5enzyme
CilostazolCytochrome P450 3A7enzyme
CilostazolCytochrome P450 1A2enzyme
CilostazolCytochrome P450 2D6enzyme
EltrombopagThrombopoietin receptortarget
EltrombopagCytochrome P450 2C8enzyme
EltrombopagCytochrome P450 1A2enzyme
EltrombopagUDP-glucuronosyltransferase 1-1enzyme
EltrombopagUDP-glucuronosyltransferase 1-3enzyme
EltrombopagSolute carrier organic anion transporter family member 1B1transporter
EltrombopagATP-binding cassette sub-family G member 2transporter
EltrombopagUDP-glucuronosyltransferase 1-9enzyme
ClonidineAlpha-2A adrenergic receptortarget
ClonidineCytochrome P450 2D6enzyme
ClonidineAlpha-2B adrenergic receptortarget
ClonidineAlpha-2C adrenergic receptortarget
ClonidineSolute carrier family 22 member 3transporter
ClonidineSolute carrier family 22 member 5transporter
ClonidineSolute carrier family 22 member 4transporter
ClonidineP-glycoprotein 1transporter
ClonidineCytochrome P450 1A2enzyme
ClonidineCytochrome P450 3A4enzyme
ClonidineCytochrome P450 1A1enzyme
ClonidineCytochrome P450 3A5enzyme
ClonidineAlpha-1A adrenergic receptortarget
ClonidineAlpha-1B adrenergic receptortarget
ClonidineAlpha-1D adrenergic receptortarget
ClonidineSerum albumincarrier
MuraglitazarPeroxisome proliferator-activated receptor alphatarget
MuraglitazarPeroxisome proliferator-activated receptor gammatarget
MuraglitazarCytochrome P450 1A2enzyme
MuraglitazarUDP-glucuronosyltransferase 1-3enzyme
MuraglitazarUDP-glucuronosyltransferase 1-1enzyme
MuraglitazarCytochrome P450 2C8enzyme
VadimezanUDP-glucuronosyltransferase 1-9enzyme
VadimezanUDP-glucuronosyltransferase 2B7enzyme
VadimezanCytochrome P450 1A2enzyme
NabumetoneProstaglandin G/H synthase 1target
NabumetoneProstaglandin G/H synthase 2target
NabumetoneMyeloperoxidaseenzyme
NabumetoneCytochrome P450 1A2enzyme
NabumetoneCytochrome P450 2C9enzyme
NabumetoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
NabumetoneAldo-keto reductase family 1 member C1enzyme
NabumetoneAldo-keto reductase family 1 member C2enzyme
NabumetoneAldo-keto reductase family 1 member C4enzyme
NabumetoneSerum albumincarrier
PazopanibVascular endothelial growth factor receptor 1target
PazopanibVascular endothelial growth factor receptor 2target
PazopanibVascular endothelial growth factor receptor 3target
PazopanibPlatelet-derived growth factor receptor alphatarget
PazopanibPlatelet-derived growth factor receptor betatarget
PazopanibMast/stem cell growth factor receptor Kittarget
PazopanibCytochrome P450 3A4enzyme
PazopanibCytochrome P450 2D6enzyme
PazopanibCytochrome P450 2C8enzyme
PazopanibCytochrome P450 1A2enzyme
PazopanibP-glycoprotein 1transporter
PazopanibATP-binding cassette sub-family G member 2transporter
PazopanibSolute carrier organic anion transporter family member 1B1transporter
PazopanibUDP-glucuronosyltransferase 1-1transporter
PazopanibFibroblast growth factor receptor 3target
PazopanibTyrosine-protein kinase ITK/TSKtarget
PazopanibFibroblast growth factor 1target
PazopanibSH2B adapter protein 3target
UlipristalProgesterone receptortarget
UlipristalGlucocorticoid receptortarget
UlipristalAndrogen receptortarget
UlipristalCytochrome P450 3A4enzyme
UlipristalCytochrome P450 1A2enzyme
UlipristalSerum albumincarrier
UlipristalAlpha-1-acid glycoprotein 1carrier
Lorcaserin5-hydroxytryptamine receptor 2Ctarget
LorcaserinCytochrome P450 1A2enzyme
LorcaserinCytochrome P450 2A6enzyme
LorcaserinCytochrome P450 2B6enzyme
LorcaserinCytochrome P450 2C19enzyme
LorcaserinCytochrome P450 2D6enzyme
LorcaserinCytochrome P450 3A4enzyme
LorcaserinDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
LorcaserinCytochrome P450 1A1enzyme
ApixabanCoagulation factor Xtarget
ApixabanCytochrome P450 3A4enzyme
ApixabanCytochrome P450 1A2enzyme
ApixabanCytochrome P450 2C8enzyme
ApixabanCytochrome P450 2C9enzyme
ApixabanCytochrome P450 2C19enzyme
ApixabanCytochrome P450 2J2enzyme
ApixabanP-glycoprotein 1transporter
ApixabanATP-binding cassette sub-family G member 2transporter
ApixabanCytochrome P450 3A5enzyme
AxitinibVascular endothelial growth factor receptor 1target
AxitinibVascular endothelial growth factor receptor 2target
AxitinibVascular endothelial growth factor receptor 3target
AxitinibCytochrome P450 3A4enzyme
AxitinibCytochrome P450 3A5enzyme
AxitinibCytochrome P450 1A2enzyme
AxitinibCytochrome P450 2C19enzyme
AxitinibUDP-glucuronosyltransferase 1-1enzyme
AxitinibP-glycoprotein 1transporter
AxitinibSolute carrier organic anion transporter family member 1B1transporter
PomalidomideCytochrome P450 1A2enzyme
PomalidomideCytochrome P450 3A4enzyme
PomalidomideP-glycoprotein 1transporter
PomalidomideProtein cereblontarget
PomalidomideTumor necrosis factortarget
PomalidomideProstaglandin G/H synthase 2target
IxazomibCytochrome P450 3A4enzyme
IxazomibCytochrome P450 1A2enzyme
IxazomibCytochrome P450 2B6enzyme
IxazomibCytochrome P450 2C8enzyme
IxazomibCytochrome P450 2D6enzyme
IxazomibCytochrome P450 2C19enzyme
IxazomibCytochrome P450 2C9enzyme
BendamustineCytochrome P450 1A2enzyme
RucaparibPoly [ADP-ribose] polymerase 1target
RucaparibPoly [ADP-ribose] polymerase 2target
RucaparibPoly [ADP-ribose] polymerase 3target
RucaparibCytochrome P450 2D6enzyme
RucaparibCytochrome P450 1A2enzyme
RucaparibCytochrome P450 3A4enzyme
RucaparibP-glycoprotein 1transporter
RucaparibATP-binding cassette sub-family G member 2transporter
RucaparibMultidrug and toxin extrusion protein 1transporter
RucaparibMultidrug and toxin extrusion protein 2transporter
RucaparibSolute carrier family 22 member 1transporter
RucaparibMultidrug resistance-associated protein 4transporter
RucaparibSolute carrier organic anion transporter family member 1B1transporter
RucaparibSolute carrier organic anion transporter family member 1B3transporter
RucaparibSolute carrier family 22 member 6transporter
RucaparibSolute carrier family 22 member 8transporter
RucaparibCytochrome P450 3A5enzyme
RucaparibCytochrome P450 3A7enzyme
RucaparibCytochrome P450 3A43enzyme
RucaparibCytochrome P450 2C19enzyme
RucaparibCytochrome P450 2C9enzyme
RucaparibCytochrome P450 2C8enzyme
RucaparibUDP-glucuronosyltransferase 1-1enzyme
IcotinibEpidermal growth factor receptortarget
IcotinibCytochrome P450 3A4enzyme
IcotinibCytochrome P450 1A2enzyme
IcotinibCytochrome P450 3A5enzyme
DeutetrabenazineSynaptic vesicular amine transportertarget
DeutetrabenazineCarbonyl reductase [NADPH] 1enzyme
DeutetrabenazineCarbonyl reductase [NADPH] 3enzyme
DeutetrabenazineCytochrome P450 2D6enzyme
DeutetrabenazineCytochrome P450 1A2enzyme
DeutetrabenazineCytochrome P450 3A5enzyme
DeutetrabenazineCytochrome P450 3A4enzyme
StiripentolCytochrome P450 2C19enzyme
StiripentolCytochrome P450 2D6enzyme
StiripentolCytochrome P450 3A4enzyme
StiripentolCytochrome P450 1A2enzyme
StiripentolCytochrome P450 2C9enzyme
StiripentolGABA(A) Receptortarget
StiripentolL-lactate dehydrogenase A chaintarget
StiripentolL-lactate dehydrogenase B chaintarget
VoxilaprevirCytochrome P450 3A4enzyme
VoxilaprevirCytochrome P450 1A2enzyme
VoxilaprevirCytochrome P450 2C8enzyme
VoxilaprevirNS3/4A proteintarget
VoxilaprevirP-glycoprotein 1transporter
VoxilaprevirATP-binding cassette sub-family G member 2transporter
VoxilaprevirSolute carrier organic anion transporter family member 1B1transporter
VoxilaprevirSolute carrier organic anion transporter family member 1B3transporter
EnasidenibCytochrome P450 1A2enzyme
EnasidenibCytochrome P450 2B6enzyme
EnasidenibIsocitrate dehydrogenase [NADP], mitochondrialtarget
EnasidenibCytochrome P450 2C8enzyme
EnasidenibCytochrome P450 2C9enzyme
EnasidenibCytochrome P450 2C19enzyme
EnasidenibCytochrome P450 2D6enzyme
EnasidenibCytochrome P450 3A4enzyme
EnasidenibUDP-glucuronosyltransferase 1-1enzyme
EnasidenibUDP-glucuronosyltransferase 1-3enzyme
EnasidenibUDP-glucuronosyltransferase 1-4enzyme
EnasidenibUDP-glucuronosyltransferase 1-9enzyme
EnasidenibUDP-glucuronosyltransferase 2B7enzyme
EnasidenibUDP-glucuronosyltransferase 2B15enzyme
EnasidenibP-glycoprotein 1transporter
EnasidenibATP-binding cassette sub-family G member 2transporter
EnasidenibSolute carrier family 22 member 6transporter
EnasidenibSolute carrier organic anion transporter family member 1B1transporter
EnasidenibSolute carrier family 22 member 2transporter
EnasidenibSolute carrier organic anion transporter family member 1B3transporter
EnasidenibSolute carrier family 22 member 8transporter
Estradiol acetateEstrogen receptor alphatarget
Estradiol acetateNuclear receptor subfamily 1 group I member 2target
Estradiol acetateSex hormone-binding globulincarrier
Estradiol acetateEstrogen receptor betatarget
Estradiol acetateCytochrome P450 1A2enzyme
Estradiol acetateUDP-glucuronosyltransferase 1-1enzyme
Estradiol acetateSerum albumincarrier
Estradiol acetateFatty acid-binding protein, intestinalcarrier
Estradiol acetateCytochrome P450 3A4enzyme
Estradiol acetateCytochrome P450 3A5enzyme
Estradiol acetateCytochrome P450 3A7enzyme
Estradiol acetateSolute carrier family 22 member 2transporter
Estradiol acetateSolute carrier family 22 member 1transporter
Estradiol acetateSolute carrier family 22 member 3transporter
Estradiol acetateSolute carrier organic anion transporter family member 2B1transporter
Estradiol acetateSolute carrier organic anion transporter family member 1A2transporter
Estradiol acetateMultidrug resistance-associated protein 7transporter
Estradiol acetateSolute carrier family 22 member 11transporter
Estradiol acetateATP-binding cassette sub-family G member 2transporter
Estradiol acetateSolute carrier organic anion transporter family member 1B1transporter
Estradiol acetateP-glycoprotein 1transporter
Estradiol acetateCytochrome P450 1A1enzyme
Estradiol acetateCytochrome P450 1B1enzyme
Estradiol acetateCytochrome P450 2C19enzyme
Estradiol acetateCytochrome P450 2C8enzyme
Estradiol acetateCytochrome P450 2C9enzyme
Estradiol acetateSolute carrier family 22 member 8transporter
Estradiol acetateSolute carrier organic anion transporter family member 1B3transporter
Estradiol acetateSolute carrier organic anion transporter family member 1C1transporter
Estradiol acetateSolute carrier organic anion transporter family member 4A1transporter
Estradiol acetateNeuronal acetylcholine receptor subunit alpha-4target
Estradiol acetateNuclear receptor coactivator 2target
Estradiol acetateG-protein coupled estrogen receptor 1target
Estradiol acetateATP synthase subunit atarget
Estradiol acetateBeclin-1target
Estradiol acetateEstradiol 17-beta-dehydrogenase 2target
Estradiol acetateEstrogen-related receptor gammatarget
Estradiol benzoateEstrogen receptor alphatarget
Estradiol benzoateNuclear receptor subfamily 1 group I member 2target
Estradiol benzoateSex hormone-binding globulincarrier
Estradiol benzoateEstrogen receptor betatarget
Estradiol benzoateCytochrome P450 1A2enzyme
Estradiol benzoateUDP-glucuronosyltransferase 1-1enzyme
Estradiol benzoateSerum albumincarrier
Estradiol benzoateFatty acid-binding protein, intestinalcarrier
Estradiol benzoateCytochrome P450 3A4enzyme
Estradiol benzoateCytochrome P450 3A5enzyme
Estradiol benzoateCytochrome P450 3A7enzyme
Estradiol benzoateSolute carrier family 22 member 2transporter
Estradiol benzoateSolute carrier family 22 member 1transporter
Estradiol benzoateSolute carrier family 22 member 3transporter
Estradiol benzoateSolute carrier organic anion transporter family member 2B1transporter
Estradiol benzoateSolute carrier organic anion transporter family member 1A2transporter
Estradiol benzoateMultidrug resistance-associated protein 7transporter
Estradiol benzoateSolute carrier family 22 member 11transporter
Estradiol benzoateATP-binding cassette sub-family G member 2transporter
Estradiol benzoateSolute carrier organic anion transporter family member 1B1transporter
Estradiol benzoateP-glycoprotein 1transporter
Estradiol benzoateCytochrome P450 1A1enzyme
Estradiol benzoateCytochrome P450 1B1enzyme
Estradiol benzoateCytochrome P450 2C19enzyme
Estradiol benzoateCytochrome P450 2C8enzyme
Estradiol benzoateCytochrome P450 2C9enzyme
Estradiol benzoateSolute carrier family 22 member 8transporter
Estradiol benzoateSolute carrier organic anion transporter family member 1B3transporter
Estradiol benzoateSolute carrier organic anion transporter family member 1C1transporter
Estradiol benzoateSolute carrier organic anion transporter family member 4A1transporter
Estradiol benzoateNeuronal acetylcholine receptor subunit alpha-4target
Estradiol benzoateNuclear receptor coactivator 2target
Estradiol benzoateG-protein coupled estrogen receptor 1target
Estradiol benzoateATP synthase subunit atarget
Estradiol benzoateBeclin-1target
Estradiol benzoateEstradiol 17-beta-dehydrogenase 2target
Estradiol benzoateEstrogen-related receptor gammatarget
Estradiol cypionateEstrogen receptor alphatarget
Estradiol cypionateNuclear receptor subfamily 1 group I member 2target
Estradiol cypionateSex hormone-binding globulincarrier
Estradiol cypionateEstrogen receptor betatarget
Estradiol cypionateCytochrome P450 1A2enzyme
Estradiol cypionateUDP-glucuronosyltransferase 1-1enzyme
Estradiol cypionateSerum albumincarrier
Estradiol cypionateFatty acid-binding protein, intestinalcarrier
Estradiol cypionateCytochrome P450 3A4enzyme
Estradiol cypionateCytochrome P450 3A5enzyme
Estradiol cypionateCytochrome P450 3A7enzyme
Estradiol cypionateSolute carrier family 22 member 2transporter
Estradiol cypionateSolute carrier family 22 member 1transporter
Estradiol cypionateSolute carrier family 22 member 3transporter
Estradiol cypionateSolute carrier organic anion transporter family member 2B1transporter
Estradiol cypionateSolute carrier organic anion transporter family member 1A2transporter
Estradiol cypionateMultidrug resistance-associated protein 7transporter
Estradiol cypionateSolute carrier family 22 member 11transporter
Estradiol cypionateATP-binding cassette sub-family G member 2transporter
Estradiol cypionateSolute carrier organic anion transporter family member 1B1transporter
Estradiol cypionateP-glycoprotein 1transporter
Estradiol cypionateCytochrome P450 1A1enzyme
Estradiol cypionateCytochrome P450 1B1enzyme
Estradiol cypionateCytochrome P450 2C19enzyme
Estradiol cypionateCytochrome P450 2C8enzyme
Estradiol cypionateCytochrome P450 2C9enzyme
Estradiol cypionateSolute carrier family 22 member 8transporter
Estradiol cypionateSolute carrier organic anion transporter family member 1B3transporter
Estradiol cypionateSolute carrier organic anion transporter family member 1C1transporter
Estradiol cypionateSolute carrier organic anion transporter family member 4A1transporter
Estradiol cypionateNeuronal acetylcholine receptor subunit alpha-4target
Estradiol cypionateNuclear receptor coactivator 2target
Estradiol cypionateG-protein coupled estrogen receptor 1target
Estradiol cypionateATP synthase subunit atarget
Estradiol cypionateBeclin-1target
Estradiol cypionateEstradiol 17-beta-dehydrogenase 2target
Estradiol cypionateEstrogen-related receptor gammatarget
Estradiol dienanthateEstrogen receptor alphatarget
Estradiol dienanthateNuclear receptor subfamily 1 group I member 2target
Estradiol dienanthateSex hormone-binding globulincarrier
Estradiol dienanthateEstrogen receptor betatarget
Estradiol dienanthateCytochrome P450 1A2enzyme
Estradiol dienanthateUDP-glucuronosyltransferase 1-1enzyme
Estradiol dienanthateSerum albumincarrier
Estradiol dienanthateFatty acid-binding protein, intestinalcarrier
Estradiol dienanthateCytochrome P450 3A4enzyme
Estradiol dienanthateCytochrome P450 3A5enzyme
Estradiol dienanthateCytochrome P450 3A7enzyme
Estradiol dienanthateSolute carrier family 22 member 2transporter
Estradiol dienanthateSolute carrier family 22 member 1transporter
Estradiol dienanthateSolute carrier family 22 member 3transporter
Estradiol dienanthateSolute carrier organic anion transporter family member 2B1transporter
Estradiol dienanthateSolute carrier organic anion transporter family member 1A2transporter
Estradiol dienanthateMultidrug resistance-associated protein 7transporter
Estradiol dienanthateSolute carrier family 22 member 11transporter
Estradiol dienanthateATP-binding cassette sub-family G member 2transporter
Estradiol dienanthateSolute carrier organic anion transporter family member 1B1transporter
Estradiol dienanthateP-glycoprotein 1transporter
Estradiol dienanthateCytochrome P450 1A1enzyme
Estradiol dienanthateCytochrome P450 1B1enzyme
Estradiol dienanthateCytochrome P450 2C19enzyme
Estradiol dienanthateCytochrome P450 2C8enzyme
Estradiol dienanthateCytochrome P450 2C9enzyme
Estradiol dienanthateSolute carrier family 22 member 8transporter
Estradiol dienanthateSolute carrier organic anion transporter family member 1B3transporter
Estradiol dienanthateSolute carrier organic anion transporter family member 1C1transporter
Estradiol dienanthateSolute carrier organic anion transporter family member 4A1transporter
Estradiol dienanthateNeuronal acetylcholine receptor subunit alpha-4target
Estradiol dienanthateNuclear receptor coactivator 2target
Estradiol dienanthateG-protein coupled estrogen receptor 1target
Estradiol dienanthateATP synthase subunit atarget
Estradiol dienanthateBeclin-1target
Estradiol dienanthateEstradiol 17-beta-dehydrogenase 2target
Estradiol dienanthateEstrogen-related receptor gammatarget
Estradiol valerateEstrogen receptor alphatarget
Estradiol valerateNuclear receptor subfamily 1 group I member 2target
Estradiol valerateSex hormone-binding globulincarrier
Estradiol valerateEstrogen receptor betatarget
Estradiol valerateCytochrome P450 1A2enzyme
Estradiol valerateUDP-glucuronosyltransferase 1-1enzyme
Estradiol valerateSerum albumincarrier
Estradiol valerateFatty acid-binding protein, intestinalcarrier
Estradiol valerateCytochrome P450 3A4enzyme
Estradiol valerateCytochrome P450 3A5enzyme
Estradiol valerateCytochrome P450 3A7enzyme
Estradiol valerateSolute carrier family 22 member 2transporter
Estradiol valerateSolute carrier family 22 member 1transporter
Estradiol valerateSolute carrier family 22 member 3transporter
Estradiol valerateSolute carrier organic anion transporter family member 2B1transporter
Estradiol valerateSolute carrier organic anion transporter family member 1A2transporter
Estradiol valerateMultidrug resistance-associated protein 7transporter
Estradiol valerateSolute carrier family 22 member 11transporter
Estradiol valerateATP-binding cassette sub-family G member 2transporter
Estradiol valerateSolute carrier organic anion transporter family member 1B1transporter
Estradiol valerateP-glycoprotein 1transporter
Estradiol valerateCytochrome P450 1A1enzyme
Estradiol valerateCytochrome P450 1B1enzyme
Estradiol valerateCytochrome P450 2C19enzyme
Estradiol valerateCytochrome P450 2C8enzyme
Estradiol valerateCytochrome P450 2C9enzyme
Estradiol valerateSolute carrier family 22 member 8transporter
Estradiol valerateSolute carrier organic anion transporter family member 1B3transporter
Estradiol valerateSolute carrier organic anion transporter family member 1C1transporter
Estradiol valerateSolute carrier organic anion transporter family member 4A1transporter
Estradiol valerateNeuronal acetylcholine receptor subunit alpha-4target
Estradiol valerateNuclear receptor coactivator 2target
Estradiol valerateG-protein coupled estrogen receptor 1target
Estradiol valerateATP synthase subunit atarget
Estradiol valerateBeclin-1target
Estradiol valerateEstradiol 17-beta-dehydrogenase 2target
Estradiol valerateEstrogen-related receptor gammatarget
ZotepineD(1) dopamine receptortarget
ZotepineDopamine D2 receptortarget
Zotepine5-hydroxytryptamine receptor 2Atarget
Zotepine5-hydroxytryptamine receptor 6target
Zotepine5-hydroxytryptamine receptor 7target
ZotepineSodium-dependent noradrenaline transportertarget
ZotepineSodium-dependent serotonin transportertarget
ZotepineCytochrome P450 1A2enzyme
ZotepineCytochrome P450 3A4enzyme
LofexidineAlpha-2A adrenergic receptortarget
LofexidineAlpha-1A adrenergic receptortarget
Lofexidine5-hydroxytryptamine receptor 1Atarget
Lofexidine5-hydroxytryptamine receptor 7target
Lofexidine5-hydroxytryptamine receptor 2Ctarget
Lofexidine5-hydroxytryptamine receptor 1Dtarget
LofexidineCytochrome P450 2D6enzyme
LofexidineCytochrome P450 1A2enzyme
LofexidineCytochrome P450 2C19enzyme
LofexidineATP-binding cassette sub-family B member 5transporter
LofexidineMultidrug and toxin extrusion protein 1transporter
TasimelteonMelatonin receptor type 1Atarget
TasimelteonMelatonin receptor type 1Btarget
TasimelteonCytochrome P450 3A4enzyme
TasimelteonCytochrome P450 1A2enzyme
PirfenidoneFurintarget
PirfenidoneCytochrome P450 1A2enzyme
Ramosetron5-hydroxytryptamine receptor 3Atarget
RamosetronCytochrome P450 1A2enzyme
AcetaminophenProstaglandin G/H synthase 1target
AcetaminophenProstaglandin G/H synthase 2target
AcetaminophenCytochrome P450 1A2enzyme
AcetaminophenCytochrome P450 2E1enzyme
AcetaminophenP-glycoprotein 1transporter
AcetaminophenCytochrome P450 2D6enzyme
AcetaminophenCytochrome P450 2A6enzyme
AcetaminophenCytochrome P450 3A4enzyme
AcetaminophenUDP-glucuronosyltransferase 1-1enzyme
AcetaminophenUDP-glucuronosyltransferase 1-6enzyme
AcetaminophenUDP-glucuronosyltransferase 1-9enzyme
AcetaminophenUDP-glucuronosyltransferase 2B15enzyme
AcetaminophenSulfotransferase 1A1enzyme
AcetaminophenSulfotransferase 1A3/1A4enzyme
AcetaminophenArylamine N-acetyltransferase 2enzyme
AcetaminophenProstaglandin E synthase 3target
AcetaminophenTransient receptor potential cation channel subfamily V member 1target
AcetaminophenSerum albumincarrier
AcetaminophenFatty-acid amide hydrolase 1enzyme
AcetaminophenGlutathione S-transferase Penzyme
AcetaminophenGlutathione S-transferase Mu 1enzyme
ClopidogrelP2Y purinoceptor 12target
ClopidogrelCytochrome P450 3A4enzyme
ClopidogrelCytochrome P450 2B6enzyme
ClopidogrelCytochrome P450 3A5enzyme
ClopidogrelCytochrome P450 2C19enzyme
ClopidogrelCytochrome P450 2C9enzyme
ClopidogrelCytochrome P450 1A2enzyme
ClopidogrelCytochrome P450 2C8enzyme
ClopidogrelLiver carboxylesterase 1enzyme
ClopidogrelP-glycoprotein 1transporter
ClopidogrelSolute carrier family 22 member 1transporter
ClopidogrelSolute carrier family 22 member 2transporter
FluvoxamineSodium-dependent serotonin transportertarget
FluvoxamineCytochrome P450 1A2enzyme
FluvoxamineCytochrome P450 2D6enzyme
FluvoxamineCytochrome P450 2C9enzyme
FluvoxamineCytochrome P450 2C19enzyme
FluvoxamineCytochrome P450 1A1enzyme
FluvoxamineCytochrome P450 3A4enzyme
FluvoxamineCytochrome P450 3A Subfamilyenzyme
FluvoxamineP-glycoprotein 1transporter
FluvoxamineCytochrome P450 2B6enzyme
FluvoxaminePotassium voltage-gated channel subfamily H member 2target
FluvoxamineBile salt export pumptransporter
TegafurCytochrome P450 2A6enzyme
TegafurThymidylate synthasetarget
TegafurCytochrome P450 1A2enzyme
TegafurCytochrome P450 2C8enzyme
TegafurCytochrome P450 2E1enzyme
TegafurCytochrome P450 3A5enzyme
TegafurThyroxine-binding globulincarrier
DihydralazineCytochrome P450 1A2enzyme
PimobendanCytochrome P450 1A2enzyme
RanitidineHistamine H2 receptortarget
RanitidineCytochrome P450 1A2enzyme
RanitidineCytochrome P450 2D6enzyme
RanitidineSolute carrier family 22 member 1transporter
RanitidineP-glycoprotein 1transporter
RanitidineSolute carrier family 22 member 8transporter
RanitidineCytochrome P450 3A4enzyme
RanitidineAcetylcholinesterasetarget
RanitidineSolute carrier family 22 member 2transporter
RanitidineAcetylcholinesteraseenzyme
PerampanelGlutamate receptor 1target
PerampanelCytochrome P450 3A4enzyme
PerampanelCytochrome P450 3A5enzyme
PerampanelCytochrome P450 1A2enzyme
PerampanelCytochrome P450 2B6enzyme
(R)-warfarinSerum albumincarrier
(R)-warfarinCytochrome P450 2C8enzyme
(R)-warfarinCytochrome P450 2C9enzyme
(R)-warfarinCytochrome P450 2C18enzyme
(R)-warfarinCytochrome P450 2C19enzyme
(R)-warfarinCytochrome P450 1A2enzyme
(R)-warfarinCytochrome P450 1A1enzyme
(R)-warfarinCytochrome P450 3A4enzyme
6-O-benzylguanineCytochrome P450 3A4enzyme
8-chlorotheophyllineAdenosine receptor A2atarget
8-chlorotheophyllineCytochrome P450 1A2enzyme
HypoxanthinePurine nucleoside phosphorylasetarget
HypoxanthineCytochrome P450 1A2enzyme
LisofyllineCytochrome P450 1A2enzyme
OxtriphyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
OxtriphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
OxtriphyllineAdenosine receptor A2atarget
OxtriphyllineAdenosine receptor A1target
OxtriphyllineCytochrome P450 1A2enzyme
OxtriphyllineSolute carrier family 22 member 7transporter
OxtriphyllineHistone deacetylase 2target
XanthinePurine nucleoside phosphorylase 2target
XanthineXanthine phosphoribosyltransferasetarget
XanthineCytochrome P450 1A2enzyme
TemafloxacinDNA gyrase subunit Atarget
TemafloxacinDNA topoisomerase 4 subunit Atarget
TemafloxacinCytochrome P450 1A2enzyme
AcefyllineCytochrome P450 1A2enzyme
AcyclovirDNA polymerase catalytic subunittarget
AcyclovirDNA polymerase catalytic subunittarget
AcyclovirThymidine kinasetarget
AcyclovirSolute carrier family 22 member 1transporter
AcyclovirSolute carrier family 22 member 6transporter
AcyclovirSolute carrier family 22 member 8transporter
AcyclovirIleal sodium/bile acid cotransportertransporter
AcyclovirMultidrug and toxin extrusion protein 1transporter
AcyclovirMultidrug and toxin extrusion protein 2transporter
AcyclovirThymidine kinaseenzyme
AcyclovirGuanylate kinaseenzyme
AcyclovirNucleoside diphosphokinaseenzyme
AcyclovirPyruvate Kinasesenzyme
AcyclovirCreatine Kinasesenzyme
AcyclovirPhosphoglycerate Kinasesenzyme
AcyclovirSuccinyl-CoA Synthetasesenzyme
AcyclovirPhosphoenolpyruvate Carboxykinasesenzyme
AcyclovirAdenylosuccinate Synthetasesenzyme
AcyclovirSerum albumincarrier
BamifyllineCytochrome P450 1A2enzyme
BromotheophyllineCytochrome P450 1A2enzyme
BufyllineCytochrome P450 1A2enzyme
DoxofyllinePhosphodiesterase 2A, cGMP-stimulatedtarget
DoxofyllineAdenosine receptor A2atarget
DoxofyllineBeta-2 adrenergic receptortarget
DoxofyllineCytochrome P450 1A2enzyme
EntecavirDNAtarget
EtamiphyllineCytochrome P450 1A2enzyme
FenethyllineCytochrome P450 1A2enzyme
PeldesinePurine nucleoside phosphorylasetarget
PemetrexedThymidylate synthasetarget
PemetrexedDihydrofolate reductasetarget
PemetrexedTrifunctional purine biosynthetic protein adenosine-3target
PemetrexedDeoxycytidine kinaseenzyme
PemetrexedBifunctional purine biosynthesis protein PURHtarget
PemetrexedEquilibrative nucleoside transporter 1enzyme
PemetrexedSolute carrier family 22 member 8transporter
PenciclovirDNA polymerase catalytic subunittarget
PenciclovirThymidine kinasetarget
PentifyllineCytochrome P450 1A2enzyme
PropentofyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
PropentofyllineCytochrome P450 1A2enzyme
ProxyphyllineCytochrome P450 1A2enzyme
PropacetamolCholinesteraseenzyme
PropacetamolProstaglandin G/H synthase 1target
PropacetamolProstaglandin G/H synthase 2target
PropacetamolTransient receptor potential cation channel subfamily V member 1target
PropacetamolCannabinoid receptor 1target
PropacetamolCytochrome P450 2E1enzyme
PropacetamolCytochrome P450 1A2enzyme
PropacetamolCytochrome P450 2D6enzyme
PropacetamolUDP-glucuronosyltransferase 1-1enzyme
PropacetamolUDP-glucuronosyltransferase 1-6enzyme
PropacetamolUDP-glucuronosyltransferase 1-9enzyme
PropacetamolUDP-glucuronosyltransferase 2B15enzyme
PropacetamolUDP-glucuronosyltransferase 1-10enzyme
PropacetamolSulfotransferase 1A1enzyme
PropacetamolSulfotransferase 1A3/1A4enzyme
PropacetamolEstrogen sulfotransferaseenzyme
PropacetamolBile salt sulfotransferaseenzyme
PropacetamolArylamine N-acetyltransferase 2enzyme
PropacetamolCytochrome P450 2C9enzyme
PropacetamolCytochrome P450 3A4enzyme
NicotineNeuronal acetylcholine receptor subunit alpha-2target
NicotineNeuronal acetylcholine receptor subunit beta-2target
NicotineNeuronal acetylcholine receptor subunit alpha-7target
NicotineNeuronal acetylcholine receptor subunit alpha-4target
NicotineNeuronal acetylcholine receptor subunit alpha-10target
NicotineNeuronal acetylcholine receptor subunit alpha-9target
NicotineCytochrome P450 2A6enzyme
NicotineCytochrome P450 2E1enzyme
NicotineCytochrome P450 2A13enzyme
NicotineCytochrome P450 2B6enzyme
NicotineNeuronal acetylcholine receptor subunit beta-4target
NicotineNeuronal acetylcholine receptor subunit alpha-3target
NicotineNeuronal acetylcholine receptor subunit alpha-5target
NicotineNeuronal acetylcholine receptor subunit alpha-6target
NicotineNeuronal acetylcholine receptor subunit beta-3target
NicotineSolute carrier family 22 member 2transporter
NicotineSolute carrier family 22 member 1transporter
NicotineSolute carrier family 22 member 3transporter
NicotineSolute carrier family 22 member 5transporter
NicotineSolute carrier family 22 member 4transporter
NicotineCytochrome P450 1A1enzyme
NicotineCytochrome P450 1A2enzyme
NicotineCytochrome P450 2C19enzyme
NicotineCytochrome P450 2C8enzyme
NicotineCytochrome P450 2C9enzyme
NicotineCytochrome P450 2D6enzyme
NicotineCytochrome P450 3A4enzyme
NicotineAmine oxidase [flavin-containing] Aenzyme
NicotineAmine oxidase [flavin-containing] Benzyme
NicotineCytochrome P450 19A1target
NicotineCholine O-acetyltransferasetarget
CarmustineGlutathione reductase, mitochondrialtarget
CarmustineDNAtarget
CarmustineRNAtarget
LomefloxacinDNA gyrase subunit Atarget
LomefloxacinDNA topoisomerase 4 subunit Atarget
LomefloxacinDNA topoisomerase 2-alphatarget
LomefloxacinCytochrome P450 1A2enzyme
LomefloxacinSolute carrier family 22 member 5transporter
LomefloxacinCanalicular multispecific organic anion transporter 1transporter
HesperetinMicrosomal triglyceride transfer protein large subunittarget
HesperetinSterol O-acyltransferase 1target
HesperetinSterol O-acyltransferase 2target
HesperetinCytochrome P450 1A2enzyme
HesperetinATP-binding cassette sub-family G member 2transporter
HesperetinSex hormone-binding globulintarget
LeflunomideDihydroorotate dehydrogenase (quinone), mitochondrialtarget
LeflunomideCytochrome P450 1A2enzyme
LeflunomideCytochrome P450 2C9enzyme
LeflunomideAryl hydrocarbon receptortarget
LeflunomideProtein-tyrosine kinase 2-betatarget
LeflunomideATP-binding cassette sub-family G member 2transporter
RofecoxibProstaglandin G/H synthase 2target
RofecoxibElastintarget
RofecoxibCytochrome P450 3A4enzyme
RofecoxibCytochrome P450 1A2enzyme
RofecoxibMultidrug resistance-associated protein 4transporter
RofecoxibProstaglandin G/H synthase 1enzyme
RofecoxibCytochrome P450 2C8enzyme
RofecoxibCytochrome P450 2C9enzyme
ThiabendazoleFumarate reductase flavoprotein subunittarget
ThiabendazoleCytochrome P450 1A2enzyme
ThiabendazoleCytochrome P450 1A1enzyme
NifedipineCytochrome P450 3A4enzyme
NifedipineCytochrome P450 2E1enzyme
NifedipineCytochrome P450 2D6enzyme
NifedipineCalmodulintarget
NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
NifedipineVoltage-dependent L-type calcium channel subunit beta-2target
NifedipinePotassium voltage-gated channel subfamily D member 3target
NifedipineVoltage-dependent T-type calcium channeltarget
NifedipineCytochrome P450 1A2enzyme
NifedipineCytochrome P450 2A6enzyme
NifedipineCytochrome P450 2C8enzyme
NifedipineCanalicular multispecific organic anion transporter 2transporter
NifedipineP-glycoprotein 1transporter
NifedipineCanalicular multispecific organic anion transporter 1transporter
NifedipineCytochrome P450 1A1enzyme
NifedipineCytochrome P450 2B6enzyme
NifedipineNuclear receptor subfamily 1 group I member 2target
NifedipineSolute carrier organic anion transporter family member 1B1transporter
NifedipineBile salt export pumptransporter
NifedipineCytochrome P450 2C9enzyme
NifedipineSerum albumincarrier
Nifedipinealpha1-acid glycoproteincarrier
NifedipineCytochrome P450 3A5enzyme
PrimaquineCytochrome P450 1A1enzyme
PrimaquineCytochrome P450 1A2enzyme
PrimaquineCytochrome P450 3A4enzyme
PrimaquineKeratin, type II cytoskeletal 7target
PrimaquineCytochrome P450 1B1enzyme
PrimaquineCytochrome P450 2D6enzyme
PrimaquineRibosyldihydronicotinamide dehydrogenase [quinone]target
PrimaquineFe(II)-protoporphyrin IXtarget
PrimaquineP-glycoprotein 1transporter
EtoricoxibProstaglandin G/H synthase 2target
EtoricoxibCytochrome P450 3A4enzyme
EtoricoxibCytochrome P450 2C9enzyme
EtoricoxibCytochrome P450 2D6enzyme
EtoricoxibCytochrome P450 1A2enzyme
EtoricoxibCytochrome P450 2C19enzyme
EtoricoxibCytochrome P450 2E1enzyme
PraziquantelSchistosome calcium ion (Ca2+) channelstarget
PraziquantelCytochrome P450 3A4enzyme
PraziquantelCytochrome P450 1A2enzyme
PraziquantelCytochrome P450 2C19enzyme
PraziquantelCytochrome P450 3A43enzyme
PraziquantelCytochrome P450 3A5enzyme
PraziquantelCytochrome P450 3A7enzyme
TriamtereneAmiloride-sensitive sodium channel subunit gammatarget
TriamtereneAmiloride-sensitive sodium channel subunit alphatarget
TriamtereneAmiloride-sensitive sodium channel subunit betatarget
TriamtereneAmiloride-sensitive sodium channel subunit deltatarget
TriamtereneCytochrome P450 1A2enzyme
DasatinibTyrosine-protein kinase ABL1target
DasatinibAbelson tyrosine-protein kinase 2target
DasatinibProto-oncogene tyrosine-protein kinase Srctarget
DasatinibTyrosine-protein kinase Fyntarget
DasatinibTyrosine-protein kinase Lcktarget
DasatinibTyrosine-protein kinase Yestarget
DasatinibMast/stem cell growth factor receptor Kittarget
DasatinibPlatelet-derived growth factor receptor betatarget
DasatinibEphrin type-A receptor 2target
DasatinibSignal transducer and activator of transcription 5Btarget
DasatinibCytochrome P450 3A4enzyme
DasatinibP-glycoprotein 1transporter
DasatinibATP-binding cassette sub-family G member 2transporter
DasatinibCytochrome P450 1A1enzyme
DasatinibCytochrome P450 1A2enzyme
DasatinibCytochrome P450 1B1enzyme
DasatinibCytochrome P450 3A5enzyme
DasatinibDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DasatinibTyrosine-protein kinase BTKtarget
DasatinibNuclear receptor subfamily 4 group A member 3target
DasatinibBreakpoint cluster region proteintarget
DasatinibTyrosine-protein kinase CSKtarget
DasatinibEphrin type-A receptor 5target
DasatinibEphrin type-B receptor 4target
DasatinibTyrosine-protein kinase Fgrtarget
DasatinibTyrosine-protein kinase FRKtarget
DasatinibHeat shock cognate 71 kDa proteintarget
DasatinibTyrosine-protein kinase Lyntarget
DasatinibMitogen-activated protein kinase kinase kinase MLTtarget
DasatinibMitogen-activated protein kinase 14target
DasatinibAmidophosphoribosyltransferasetarget
Benzyl alcoholCytochrome P450 2C8enzyme
Benzyl alcoholCytochrome P450 1A1enzyme
Benzyl alcoholAldehyde dehydrogenase, mitochondrialenzyme
Benzyl alcoholCytochrome P450 1A2enzyme
Benzyl alcoholCytochrome P450 2E1enzyme
Benzyl alcoholCytochrome P450 2D6enzyme
CapsaicinCytochrome P450 3A4enzyme
CapsaicinProstaglandin G/H synthase 2enzyme
CapsaicinMyeloperoxidaseenzyme
CapsaicinCytochrome P450 1A2enzyme
CapsaicinCytochrome P450 2E1enzyme
CapsaicinAmine oxidase [flavin-containing] Aenzyme
CapsaicinDopamine beta-hydroxylaseenzyme
CapsaicinGlutamine synthetaseenzyme
CapsaicinCholinesteraseenzyme
CapsaicinTransient receptor potential cation channel subfamily V member 1target
CapsaicinProhibitin-2target
BinimetinibInterleukin-6target
BinimetinibTumor necrosis factortarget
BinimetinibInterleukin-1 betatarget
BinimetinibUDP-glucuronosyltransferase 1-1enzyme
BinimetinibCytochrome P450 1A2enzyme
BinimetinibCytochrome P450 2C19enzyme
BinimetinibMitogen-activated protein kinase kinase kinase 1target
BinimetinibDual specificity mitogen-activated protein kinase kinase 2target
AzathioprineThiopurine S-methyltransferaseenzyme
AzathioprineXanthine dehydrogenase/oxidaseenzyme
AzathioprineGlutathione S-transferase A1enzyme
AzathioprineGlutathione S-transferase A2enzyme
AzathioprineGlutathione S-transferase Mu 1enzyme
AzathioprineRas-related C3 botulinum toxin substrate 1target
AzathioprineCytochrome P450 1A2enzyme
AzathioprineHypoxanthine-guanine phosphoribosyltransferaseenzyme
AzathioprineNucleotide triphosphate diphosphatase NUDT15enzyme
AzathioprineEquilibrative nucleoside transporter 2transporter
AzathioprineSolute carrier family 28 member 3transporter
AzathioprineP-glycoprotein 1transporter
AzathioprineSolute carrier family 43 member 3transporter
AzathioprineSerum albumincarrier
AzathioprineInosine-5'-monophosphate dehydrogenase 1enzyme
AzathioprineInosine-5'-monophosphate dehydrogenase 2enzyme
AzathioprineGMP synthase [glutamine-hydrolyzing]enzyme
AzathioprineInosine triphosphate pyrophosphataseenzyme
8-azaguaninePurine nucleoside phosphorylasetarget
8-azaguanineCytochrome P450 1A2enzyme
9-DeazaguanineHypoxanthine-guanine phosphoribosyltransferasetarget
9-DeazaguanineCytochrome P450 1A2enzyme
9-MethylguanineDihydroneopterin aldolasetarget
9-MethylguanineCytochrome P450 1A2enzyme
DisopyramideSodium channel protein type 5 subunit alphatarget
DisopyramideAlpha-1-acid glycoprotein 1carrier
DisopyramideCytochrome P450 3A4enzyme
DisopyramideMuscarinic acetylcholine receptor M1target
DisopyramideMuscarinic acetylcholine receptor M2target
DisopyramideMuscarinic acetylcholine receptor M3target
DisopyramidePotassium voltage-gated channel subfamily D member 2target
DisopyramidePotassium voltage-gated channel subfamily D member 3target
DisopyramideSolute carrier family 22 member 2transporter
DisopyramideSolute carrier family 22 member 1transporter
DisopyramidePotassium voltage-gated channel subfamily H member 2target
DisopyramideAlpha-1-acid glycoprotein 2target
DisopyramideCytochrome P450 1A2enzyme
Alosetron5-hydroxytryptamine receptor 3Atarget
AlosetronCytochrome P450 1A2enzyme
AlosetronCytochrome P450 2C9enzyme
AlosetronCytochrome P450 3A4enzyme
AlosetronCytochrome P450 2E1enzyme
SorafenibSerine/threonine-protein kinase B-raftarget
SorafenibReceptor-type tyrosine-protein kinase FLT3target
SorafenibRAF proto-oncogene serine/threonine-protein kinasetarget
SorafenibVascular endothelial growth factor receptor 3target
SorafenibPlatelet-derived growth factor receptor betatarget
SorafenibMast/stem cell growth factor receptor Kittarget
SorafenibVascular endothelial growth factor receptor 2target
SorafenibCytochrome P450 3A4enzyme
SorafenibUDP-glucuronosyltransferase 1-9enzyme
SorafenibCytochrome P450 2B6enzyme
SorafenibCytochrome P450 2C8enzyme
SorafenibCytochrome P450 3A5enzyme
SorafenibCytochrome P450 3A7enzyme
SorafenibCytochrome P450 2C9enzyme
SorafenibMultidrug resistance-associated protein 4transporter
SorafenibP-glycoprotein 1transporter
SorafenibCanalicular multispecific organic anion transporter 1transporter
SorafenibATP-binding cassette sub-family G member 2transporter
SorafenibCytochrome P450 1A2enzyme
SorafenibCytochrome P450 2C19enzyme
SorafenibCytochrome P450 2D6enzyme
SorafenibUDP-glucuronosyltransferase 1-1enzyme
SorafenibRalA-binding protein 1transporter
SorafenibFibroblast growth factor receptor 1target
SorafenibProto-oncogene tyrosine-protein kinase receptor Rettarget
SorafenibVascular endothelial growth factor receptor 1target
SorafenibSolute carrier organic anion transporter family member 1B1transporter
Agomelatine5-hydroxytryptamine receptor 2Ctarget
AgomelatineMelatonin receptor type 1Btarget
AgomelatineMelatonin receptor type 1Atarget
AgomelatineCytochrome P450 2C9enzyme
AgomelatineCytochrome P450 1A2enzyme
TocainideSodium channel protein type 5 subunit alphatarget
TocainideSerum albumincarrier
TocainideCytochrome P450 1A2enzyme
TriclabendazoleCytochrome P450 1A2enzyme
TriclabendazoleCytochrome P450 2C9enzyme
TriclabendazoleExcretory Secretory (ES) proteinstarget
TriclabendazoleCytochrome P450 3A4enzyme
TriclabendazoleCytochrome P450 1A1enzyme
TriclabendazoleCytochrome P450 1B1enzyme
TriclabendazoleCytochrome P450 2C19enzyme
TriclabendazoleCytochrome P450 2D6enzyme
TriclabendazoleCytochrome P450 2A6enzyme
TriclabendazoleCytochrome P450 2C8enzyme
TriclabendazoleCytochrome P450 2B6enzyme
DapagliflozinSodium/glucose cotransporter 2target
DapagliflozinCytochrome P450 1A1enzyme
DapagliflozinCytochrome P450 1A2enzyme
DapagliflozinCytochrome P450 2A6enzyme
DapagliflozinCytochrome P450 2C9enzyme
DapagliflozinCytochrome P450 2D6enzyme
DapagliflozinCytochrome P450 3A4enzyme
DapagliflozinUDP-glucuronosyltransferase 1-9enzyme
DapagliflozinUDP-glucuronosyltransferase 2B4enzyme
DapagliflozinUDP-glucuronosyltransferase 2B7enzyme
DapagliflozinP-glycoprotein 1transporter
ApremilastPhosphodiesterase isozyme 4target
ApremilastCytochrome P450 3A4enzyme
ApremilastCytochrome P450 2A6enzyme
ApremilastCytochrome P450 1A2enzyme
ApremilastP-glycoprotein 1transporter
ParoxetineSodium-dependent serotonin transportertarget
ParoxetineSodium-dependent noradrenaline transportertarget
Paroxetine5-hydroxytryptamine receptor 2Atarget
ParoxetineCytochrome P450 2D6enzyme
ParoxetineCytochrome P450 2C9enzyme
ParoxetineP-glycoprotein 1transporter
ParoxetineCytochrome P450 2B6enzyme
ParoxetineCytochrome P450 1A2enzyme
ParoxetineCytochrome P450 3A4enzyme
ParoxetineAlpha-1 adrenergic receptorstarget
ParoxetineAlpha-2 adrenergic receptorstarget
ParoxetineBeta adrenergic receptortarget
ParoxetineDopamine D2 receptortarget
ParoxetineHistamine H1 receptortarget
ParoxetineSerotonin Receptorstarget
ParoxetineMuscarinic acetylcholine receptortarget
Paroxetine5-hydroxytryptamine receptor 2Btarget
ParoxetineD(1) dopamine receptortarget
ParoxetineCytochrome P450 2C19enzyme
TamoxifenEstrogen receptor alphatarget
TamoxifenEstrogen receptor betatarget
TamoxifenCytochrome P450 2C9enzyme
TamoxifenCytochrome P450 3A4enzyme
TamoxifenCytochrome P450 2D6enzyme
TamoxifenCytochrome P450 2C8enzyme
TamoxifenCytochrome P450 2B6enzyme
TamoxifenLiver carboxylesterase 1enzyme
TamoxifenCytochrome P450 3A5enzyme
TamoxifenCytochrome P450 1A1enzyme
TamoxifenCytochrome P450 1B1enzyme
TamoxifenCytochrome P450 2C19enzyme
TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
TamoxifenCytochrome P450 3A7enzyme
TamoxifenP-glycoprotein 1transporter
TamoxifenATP-binding cassette sub-family G member 2transporter
TamoxifenCytochrome P450 19A1enzyme
TamoxifenCytochrome P450 2A6enzyme
TamoxifenCytochrome P450 2E1enzyme
TamoxifenUDP-glucuronosyltransferase 1-10enzyme
TamoxifenSulfotransferase 1A1enzyme
TamoxifenCanalicular multispecific organic anion transporter 1transporter
Tamoxifen3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerasetarget
TamoxifenProtein kinase Ctarget
TamoxifenAndrogen receptortarget
TamoxifenPotassium voltage-gated channel subfamily H member 2target
TamoxifenNuclear receptor subfamily 1 group I member 2target
TamoxifenEstrogen-related receptor gammatarget
TamoxifenSex hormone-binding globulintarget
TamoxifenBile salt export pumptransporter
TamoxifenThyroxine-binding globulincarrier
TamoxifenBile salt sulfotransferaseenzyme
TamoxifenCytochrome P450 1A2enzyme
TamoxifenUDP-glucuronosyltransferase 2B7enzyme
TamoxifenUDP-glucuronosyltransferase 2B17enzyme
TamoxifenEstrogen sulfotransferaseenzyme
TamoxifenATP-binding cassette sub-family A member 1transporter
TamoxifenMitogen-activated protein kinase 8target
TamoxifenSerum albumincarrier
IstradefyllineCytochrome P450 1A1enzyme
IstradefyllineCytochrome P450 3A4enzyme
IstradefyllineCytochrome P450 3A5enzyme
IstradefyllineCytochrome P450 1A2enzyme
IstradefyllineCytochrome P450 2B6enzyme
IstradefyllineCytochrome P450 2C8enzyme
IstradefyllineCytochrome P450 2C9enzyme
IstradefyllineCytochrome P450 2C18enzyme
IstradefyllineCytochrome P450 2D6enzyme
IstradefyllineCytochrome P450 3A Subfamilyenzyme
IstradefyllineP-glycoprotein 1transporter
IstradefyllineAdenosine receptor A2atarget
IstradefyllineAdenosine receptor A1target
IstradefyllineSerum albumincarrier
Istradefyllinealpha1-acid glycoproteincarrier
IstradefyllineATP-binding cassette sub-family G member 2transporter
IstradefyllineSolute carrier organic anion transporter family member 1B1transporter
IstradefyllineSolute carrier organic anion transporter family member 1B3transporter
IstradefyllineSolute carrier family 22 member 6transporter
IstradefyllinePOU domain, class 2, transcription factor 2transporter
IstradefyllineMultidrug and toxin extrusion protein 1transporter
IstradefyllineMultidrug and toxin extrusion protein 2transporter
EfavirenzCytochrome P450 2B6enzyme
EfavirenzCytochrome P450 3A4enzyme
EfavirenzCytochrome P450 2C19enzyme
EfavirenzCytochrome P450 2C9enzyme
EfavirenzCytochrome P450 1A2enzyme
EfavirenzCytochrome P450 2D6enzyme
EfavirenzReverse transcriptase/RNaseHtarget
EfavirenzCytochrome P450 2C8enzyme
EfavirenzSerum albumincarrier
EfavirenzCytochrome P450 3A5enzyme
EfavirenzCytochrome P450 3A7enzyme
EfavirenzUDP-glucuronosyltransferase 1-1enzyme
EfavirenzBile salt export pumptransporter
EfavirenzSolute carrier family 22 member 1transporter
MetoclopramideMuscarinic acetylcholine receptor M1target
MetoclopramideDopamine D2 receptortarget
MetoclopramideCytochrome P450 2D6enzyme
Metoclopramide5-hydroxytryptamine receptor 4target
Metoclopramide5-hydroxytryptamine receptor 3Atarget
MetoclopramideCytochrome P450 3A4enzyme
MetoclopramideCytochrome P450 1A2enzyme
MetoclopramideP-glycoprotein 1transporter
MetoclopramideAlpha-1-acid glycoprotein 1carrier
LoratadineHistamine H1 receptortarget
LoratadineCytochrome P450 3A4enzyme
LoratadineCytochrome P450 2C19enzyme
LoratadineCytochrome P450 2D6enzyme
LoratadineCytochrome P450 2C8enzyme
LoratadineP-glycoprotein 1transporter
LoratadinePotassium voltage-gated channel subfamily H member 2target
LoratadineBile salt export pumptransporter
LoratadineCytochrome P450 1A1enzyme
LoratadineCytochrome P450 1A2enzyme
LoratadineCytochrome P450 2B6enzyme
LoratadineCytochrome P450 2C9enzyme
LoratadineCytochrome P450 3A5enzyme
LoratadineUDP-glucuronosyltransferase 2B10enzyme
LoratadineUDP-glucuronosyltransferase 1-1enzyme
LoratadineUDP-glucuronosyltransferase 1-3enzyme
LoratadineUDP-glucuronosyltransferase 2B15enzyme
GTS-21Neuronal acetylcholine receptor subunit alpha-7target
GTS-21Cytochrome P450 1A2enzyme
GTS-21Cytochrome P450 2E1enzyme
BicifadineSodium-dependent noradrenaline transportertarget
BicifadineSodium-dependent serotonin transportertarget
BicifadineDopamine D2 receptortarget
BicifadineCytochrome P450 2D6enzyme
BicifadineAmine oxidase [flavin-containing] Benzyme
BicifadineCytochrome P450 1A2enzyme
BicifadineAmine oxidase [flavin-containing] Aenzyme
FlecainideSodium channel protein type 5 subunit alphatarget
FlecainideCytochrome P450 2D6enzyme
FlecainideSodium channel protein type 4 subunit alphatarget
FlecainideCytochrome P450 2C9enzyme
FlecainidePotassium voltage-gated channel subfamily H member 2target
Flecainidealpha1-acid glycoproteincarrier
FlecainideSerum albumincarrier
FlecainideCytochrome P450 1A2enzyme
FlecainideP-glycoprotein 1transporter
FlecainideMultidrug and toxin extrusion protein 1transporter
FlecainideRyanodine receptor 2target
NorethisteroneProgesterone receptortarget
NorethisteroneP-glycoprotein 1transporter
NorethisteroneCytochrome P450 2C19enzyme
NorethisteroneSerum albumincarrier
NorethisteroneSex hormone-binding globulincarrier
NorethisteroneAldo-keto reductase family 1 member C4enzyme
Norethisterone3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
Norethisterone3-oxo-5-alpha-steroid 4-dehydrogenaseenzyme
Norethisterone3-oxo-5-beta-steroid 4-dehydrogenaseenzyme
NorethisteroneCytochrome P450 3A4enzyme
NorethisteroneCytochrome P450 1A2enzyme
NorethisteroneCytochrome P450 2A6enzyme
NorethisteroneGlucocorticoid receptortarget
NorethisteroneAndrogen receptortarget
Lumateperone5-hydroxytryptamine receptor 2Atarget
LumateperoneDopamine D2 receptortarget
LumateperoneDopamine D1 receptortarget
LumateperoneSodium-dependent serotonin transportertarget
LumateperoneGlutamate receptor ionotropic, NMDA 2Btarget
LumateperoneAldo-keto reductase familyenzyme
LumateperoneCytochrome P450 3A4enzyme
LumateperoneCytochrome P450 2C8enzyme
LumateperoneCytochrome P450 1A2enzyme
LumateperoneUDP-glucuronosyltransferase 1-1enzyme
LumateperoneUDP-glucuronosyltransferase 1-4enzyme
LumateperoneUDP-glucuronosyltransferase 2B15enzyme
LumateperoneAldo-keto reductase family 1 member C1enzyme
LumateperoneAldo-keto reductase family 1 member B10enzyme
LumateperoneAldo-keto reductase family 1 member C4enzyme
EthinylestradiolEstrogen receptor alphatarget
EthinylestradiolNuclear receptor subfamily 1 group I member 2target
EthinylestradiolCytochrome P450 3A4enzyme
EthinylestradiolCytochrome P450 2C8enzyme
EthinylestradiolBile salt export pumptransporter
EthinylestradiolSodium/bile acid cotransportertransporter
EthinylestradiolCanalicular multispecific organic anion transporter 1transporter
EthinylestradiolP-glycoprotein 1transporter
EthinylestradiolUDP-glucuronosyltransferase 1-1enzyme
EthinylestradiolCytochrome P450 2C19enzyme
EthinylestradiolUDP-glucuronosyltransferase 1-4enzyme
EthinylestradiolUDP-glucuronosyltransferase 1-9enzyme
EthinylestradiolCytochrome P450 2C9enzyme
EthinylestradiolCytochrome P450 1A2enzyme
EthinylestradiolEstrogen sulfotransferaseenzyme
EthinylestradiolSulfotransferase 1A3/1A4enzyme
EthinylestradiolCytochrome P450 3A5enzyme
EthinylestradiolUDP-glucuronosyltransferase 2B7enzyme
EthinylestradiolUDP-glucuronosyltransferase 1-3enzyme
EthinylestradiolCatechol O-methyltransferaseenzyme
EthinylestradiolSolute carrier organic anion transporter family member 1A2transporter
EthinylestradiolSerum albumincarrier
EthinylestradiolSex hormone-binding globulincarrier
TrimethoprimDihydrofolate reductasetarget
TrimethoprimCytochrome P450 2C8enzyme
TrimethoprimCytochrome P450 3A4enzyme
TrimethoprimP-glycoprotein 1transporter
TrimethoprimCytochrome P450 2C9enzyme
TrimethoprimCytochrome P450 1A2enzyme
TrimethoprimMultidrug and toxin extrusion protein 1transporter
TrimethoprimMultidrug and toxin extrusion protein 2transporter
UmifenovirUDP-glucuronosyltransferase 1-9enzyme
UmifenovirUDP-glucuronosyltransferase 2B7enzyme
UmifenovirCytochrome P450 3A4enzyme
UmifenovirCytochrome P450 2E1enzyme
UmifenovirCytochrome P450 1A2enzyme
UmifenovirCytochrome P450 2D6enzyme
UmifenovirCytochrome P450 2C9enzyme
UmifenovirCytochrome P450 3A5enzyme
UmifenovirDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
UmifenovirDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
LopinavirHuman immunodeficiency virus type 1 proteasetarget
LopinavirCytochrome P450 3A4enzyme
LopinavirCytochrome P450 2D6enzyme
LopinavirCytochrome P450 2C19enzyme
LopinavirP-glycoprotein 1transporter
LopinavirCytochrome P450 2B6enzyme
LopinavirCytochrome P450 2C9enzyme
LopinavirCytochrome P450 3A Subfamilyenzyme
LopinavirSolute carrier organic anion transporter family member 1B1transporter
LopinavirSolute carrier organic anion transporter family member 1B3transporter
LopinavirBile salt export pumptransporter
LopinavirCytochrome P450 1A2enzyme
LopinavirAlpha-1-acid glycoprotein 1carrier
LopinavirSerum albumincarrier
SelumetinibDual specificity mitogen-activated protein kinase kinase 1target
SelumetinibDual specificity mitogen-activated protein kinase kinase 2target
SelumetinibSerum albumincarrier
Selumetinibalpha1-acid glycoproteincarrier
SelumetinibP-glycoprotein 1transporter
SelumetinibATP-binding cassette sub-family G member 2transporter
SelumetinibCytochrome P450 2C19enzyme
SelumetinibUDP-glucuronosyltransferase 1-1enzyme
SelumetinibCytochrome P450 2C9enzyme
SelumetinibCytochrome P450 3A4enzyme
SelumetinibCytochrome P450 1A2enzyme
SelumetinibCytochrome P450 2C8enzyme
SelumetinibUDP-glucuronosyltransferase 1-3enzyme
SelumetinibCytochrome P450 2E1enzyme
SelumetinibCytochrome P450 3A5enzyme
Fenfluramine5-hydroxytryptamine receptor 2Ctarget
Fenfluramine5-hydroxytryptamine receptor 2Btarget
FenfluramineCytochrome P450 2D6enzyme
FenfluramineSodium-dependent serotonin transportertarget
Fenfluramine5-hydroxytryptamine receptor 2Atarget
FenfluramineSodium-dependent serotonin transportertransporter
Fenfluramine5-hydroxytryptamine receptor 1Dtarget
FenfluramineSigma non-opioid intracellular receptor 1target
Fenfluramine5-hydroxytryptamine receptor 1Atarget
FenfluramineCytochrome P450 1A2enzyme
FenfluramineCytochrome P450 2B6enzyme
FenfluramineCytochrome P450 2C9enzyme
FenfluramineCytochrome P450 2C19enzyme
FenfluramineCytochrome P450 3A4enzyme
FenfluramineCytochrome P450 3A5enzyme