Urinary Bladder, Overactive

Also known as: Urinary Bladder Overactive / Overactive Bladder Syndrome / Overactive Urinary Bladder / Over Active Bladder / Overactive Bladder / Overactive Bladder (OAB) / Bladder, Overactive / Hypertonic bladder / Hyperactive bladder / Detrusor muscle hyperactivity / Hypertonicity of bladder

DrugDrug NameDrug Description
DB00083Botulinum toxin type AA purified form of botulinum toxin type A used to block acetylcholine release in the treatment of chronic sialorrhea, muscle spasticity, and dystonia, as well as in cosmetic applications.
DB00496DarifenacinAn M3 muscarinic receptor blocker used to treat urinary incontinence.
DB06702FesoterodineAn antimuscarinic agent used in the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency.
DB08893MirabegronA beta-3 adrenergic agonist used to treat urge urinary incontinence, urinary frequency and urgency associated with overactive bladder (OAB).
DB01062OxybutyninAn antimuscarinic agent that reduces detrusor muscle activity, relaxing the bladder and preventing the urge to void.
DB12278PropiverineAn antimuscarinic agent used to treat urinary incontinence or increased urinary frequency or urgency.
DB01591SolifenacinA muscarinic antagonist with antispasmodic properties used to treat urge urinary incontinence, urgency, and urinary frequency associated with an overactive bladder.
DB01036TolterodineA muscarinic receptor antagonist used to treat overactive bladder with urinary incontinence, urgency, and frequency.
DB00209TrospiumAn antimuscarinic agent used to treat the symptoms of overactive bladder (OAB).
DrugDrug NameTargetType
DB00083Botulinum toxin type ASynaptosomal-associated protein 25target
DB00083Botulinum toxin type ARho-related GTP-binding protein RhoBtarget
DB00496DarifenacinMuscarinic acetylcholine receptor M3target
DB00496DarifenacinCytochrome P450 3A4enzyme
DB00496DarifenacinCytochrome P450 2D6enzyme
DB00496DarifenacinMuscarinic acetylcholine receptor M1target
DB00496DarifenacinMuscarinic acetylcholine receptor M2target
DB00496DarifenacinMuscarinic acetylcholine receptor M4target
DB00496DarifenacinMuscarinic acetylcholine receptor M5target
DB06702FesoterodineMuscarinic acetylcholine receptor M1target
DB06702FesoterodineMuscarinic acetylcholine receptor M3target
DB06702FesoterodineCytochrome P450 3A4enzyme
DB06702FesoterodineMuscarinic acetylcholine receptor M2target
DB06702FesoterodineMuscarinic acetylcholine receptor M4target
DB06702FesoterodineMuscarinic acetylcholine receptor M5target
DB06702FesoterodineCytochrome P450 2D6enzyme
DB06702FesoterodineP-glycoprotein 1transporter
DB08893MirabegronCytochrome P450 3A4enzyme
DB08893MirabegronCytochrome P450 2D6enzyme
DB08893MirabegronP-glycoprotein 1transporter
DB08893MirabegronSolute carrier organic anion transporter family member 1A2transporter
DB08893MirabegronSerum albumincarrier
DB08893MirabegronAlpha-1-acid glycoprotein 1carrier
DB08893MirabegronCholinesteraseenzyme
DB08893MirabegronBeta-3 adrenergic receptortarget
DB01062OxybutyninMuscarinic acetylcholine receptor M1target
DB01062OxybutyninMuscarinic acetylcholine receptor M2target
DB01062OxybutyninMuscarinic acetylcholine receptor M3target
DB01062OxybutyninCytochrome P450 3A4enzyme
DB01062OxybutyninCytochrome P450 2C8enzyme
DB01062OxybutyninCytochrome P450 2D6enzyme
DB01062OxybutyninCytochrome P450 3A5enzyme
DB01062OxybutyninAlpha-1-acid glycoprotein 1carrier
DB01062OxybutyninSerum albumincarrier
DB12278PropiverineMuscarinic acetylcholine receptor M1target
DB12278PropiverineMuscarinic acetylcholine receptor M2target
DB12278PropiverineMuscarinic acetylcholine receptor M3target
DB12278PropiverineMuscarinic acetylcholine receptor M4target
DB12278PropiverineMuscarinic acetylcholine receptor M5target
DB12278PropiverineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB12278PropiverineAlpha-1A adrenergic receptortarget
DB12278PropiverineCytochrome P450 3A4enzyme
DB12278PropiverineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB12278PropiverineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB01591SolifenacinMuscarinic acetylcholine receptor M3target
DB01591SolifenacinMuscarinic acetylcholine receptor M1target
DB01591SolifenacinCytochrome P450 3A4enzyme
DB01591SolifenacinMuscarinic acetylcholine receptor M2target
DB01591SolifenacinMuscarinic acetylcholine receptor M4target
DB01591SolifenacinMuscarinic acetylcholine receptor M5target
DB01591Solifenacinalpha1-acid glycoproteincarrier
DB01591SolifenacinCytochrome P450 1A1enzyme
DB01591SolifenacinCytochrome P450 2D6enzyme
DB01036TolterodineMuscarinic acetylcholine receptor M1target
DB01036TolterodineMuscarinic acetylcholine receptor M2target
DB01036TolterodineMuscarinic acetylcholine receptor M3target
DB01036TolterodineCytochrome P450 2D6enzyme
DB01036TolterodineCytochrome P450 3A4enzyme
DB01036TolterodineCytochrome P450 2C9enzyme
DB01036TolterodineCytochrome P450 2C19enzyme
DB01036TolterodineMuscarinic acetylcholine receptor M4target
DB01036TolterodineMuscarinic acetylcholine receptor M5target
DB00209TrospiumMuscarinic acetylcholine receptor M1target
DB00209TrospiumCytochrome P450 2D6enzyme
DrugDrug NamePhaseStatusCount
DB00083Botulinum toxin type A1Completed1
DB00567Cephalexin1Terminated1
DB06702Fesoterodine1Completed3
DB11902Gisadenafil1Completed1
DB01137Levofloxacin1Terminated1
DB08893Mirabegron1Completed3
DB01062Oxybutynin1Completed1
DB00203Sildenafil1Completed1
DB06190Solabegron1Completed2
DB01591Solifenacin1Completed5
DB00706Tamsulosin1Completed2
DB01036Tolterodine1Completed4
DB01036Tolterodine1Terminated1
DB14895Vibegron1Completed2
DB14895Vibegron1Terminated1
DB00682Warfarin1Completed2
DB00083Botulinum toxin type A1 / 2Completed1
DB01093Dimethyl sulfoxide1 / 2Completed1
DB08893Mirabegron1 / 2Active Not Recruiting1
DB05072AV6082Terminated1
DB00083Botulinum toxin type A2Completed5
DB00083Botulinum toxin type A2Terminated2
DB00083Botulinum toxin type A2Withdrawn1
DB06634Casopitant2Completed1
DB06634Casopitant2Terminated1
DB00035Desmopressin2Completed1
DB11807Dexmecamylamine2Completed1
DB06702Fesoterodine2Completed2
DB06702Fesoterodine2Recruiting1
DB11902Gisadenafil2Completed1
DB09262Imidafenacin2Completed1
DB04465Lactose2Completed1
DB08893Mirabegron2Completed6
DB08893Mirabegron2Recruiting1
DB15325ONO-85392Completed1
DB01062Oxybutynin2Recruiting1
DB00230Pregabalin2Completed1
DB12278Propiverine2Completed1
DB12080Ritobegron2Completed1
DB12626Senrebotase2Completed1
DB12973Serlopitant2Completed1
DB06190Solabegron2Completed3
DB01591Solifenacin2Completed4
DB01591Solifenacin2Recruiting2
DB01036Tolterodine2Completed7
DB01036Tolterodine2Terminated1
DB00862Vardenafil2Completed1
DB14895Vibegron2Completed1
DB00083Botulinum toxin type A2 / 3Unknown Status1
DB00706Tamsulosin2 / 3Completed1
DB01036Tolterodine2 / 3Completed2
DB00083Botulinum toxin type A3Completed9
DB00083Botulinum toxin type A3Enrolling by Invitation1
DB00083Botulinum toxin type A3Recruiting2
DB00083Botulinum toxin type A3Terminated4
DB00496Darifenacin3Completed3
DB01093Dimethyl sulfoxide3Terminated1
DB06702Fesoterodine3Completed8
DB09262Imidafenacin3Completed3
DB00281Lidocaine3Terminated1
DB08893Mirabegron3Completed14
DB08893Mirabegron3Recruiting2
DB01062Oxybutynin3Completed3
DB01062Oxybutynin3Recruiting2
DB12278Propiverine3Completed2
DB12080Ritobegron3Completed1
DB12080Ritobegron3Withdrawn1
DB01591Solifenacin3Completed15
DB01591Solifenacin3Recruiting2
DB01591Solifenacin3Terminated2
DB01036Tolterodine3Completed15
DB00209Trospium3Completed1
DB14895Vibegron3Completed2
DB14895Vibegron3Enrolling by Invitation1
DB14895Vibegron3Recruiting1
DB00316Acetaminophen4Completed1
DB00207Azithromycin4Completed1
DB00181Baclofen4Terminated1
DB13913Belladonna4Completed1
DB13913Belladonna4Terminated1
DB00083Botulinum toxin type A4Active Not Recruiting2
DB00083Botulinum toxin type A4Completed5
DB00083Botulinum toxin type A4Not Yet Recruiting1
DB00083Botulinum toxin type A4Recruiting1
DB00286Conjugated estrogens4Completed1
DB00286Conjugated estrogens4Recruiting1
DB00496Darifenacin4Completed3
DB00590Doxazosin4Unknown Status1
DB00254Doxycycline4Completed1
DB01175Escitalopram4Completed1
DB00783Estradiol4Completed2
DB00783Estradiol4Recruiting1
DB06702Fesoterodine4Completed10
DB06702Fesoterodine4Recruiting1
DB06702Fesoterodine4Terminated2
DB09262Imidafenacin4Completed2
DB00281Lidocaine4Completed1
DB08893Mirabegron4Completed10
DB08893Mirabegron4Not Yet Recruiting1
DB08893Mirabegron4Recruiting5
DB08893Mirabegron4Unknown Status1
DB08893Mirabegron4Withdrawn1
DB00295Morphine4Completed1
DB11130Opium4Terminated1
DB01062Oxybutynin4Completed5
DB01062Oxybutynin4Unknown Status1
DB00497Oxycodone4Completed1
DB12278Propiverine4Completed3
DB08839Serotonin4Completed1
DB09484Sodium fluorophosphate4Not Yet Recruiting1
DB01591Solifenacin4Completed21
DB01591Solifenacin4Recruiting3
DB01591Solifenacin4Terminated1
DB01591Solifenacin4Unknown Status1
DB01591Solifenacin4Withdrawn1
DB01015Sulfamethoxazole4Recruiting1
DB00706Tamsulosin4Completed6
DB00706Tamsulosin4Not Yet Recruiting1
DB01036Tolterodine4Completed9
DB01036Tolterodine4Terminated1
DB01036Tolterodine4Unknown Status2
DB00440Trimethoprim4Recruiting1
DB00209Trospium4Completed5
DB00083Botulinum toxin type ANot AvailableActive Not Recruiting1
DB00083Botulinum toxin type ANot AvailableCompleted5
DB00083Botulinum toxin type ANot AvailableRecruiting1
DB00083Botulinum toxin type ANot AvailableTerminated1
DB00286Conjugated estrogensNot AvailableCompleted2
DB00496DarifenacinNot AvailableActive Not Recruiting1
DB00496DarifenacinNot AvailableCompleted4
DB00496DarifenacinNot AvailableTerminated1
DB00783EstradiolNot AvailableCompleted2
DB06702FesoterodineNot AvailableActive Not Recruiting1
DB06702FesoterodineNot AvailableCompleted8
DB06702FesoterodineNot AvailableUnknown Status2
DB09262ImidafenacinNot AvailableActive Not Recruiting1
DB09262ImidafenacinNot AvailableCompleted1
DB08893MirabegronNot AvailableActive Not Recruiting1
DB08893MirabegronNot AvailableCompleted7
DB08893MirabegronNot AvailableNot Yet Recruiting1
DB09567Olive oilNot AvailableTerminated1
DB01062OxybutyninNot AvailableActive Not Recruiting1
DB01062OxybutyninNot AvailableCompleted3
DB01062OxybutyninNot AvailableNot Yet Recruiting1
DB12278PropiverineNot AvailableCompleted1
DB01591SolifenacinNot AvailableCompleted8
DB01591SolifenacinNot AvailableRecruiting1
DB01591SolifenacinNot AvailableUnknown Status3
DB01036TolterodineNot AvailableActive Not Recruiting1
DB01036TolterodineNot AvailableCompleted5
DB01036TolterodineNot AvailableNot Yet Recruiting1
DB00209TrospiumNot AvailableActive Not Recruiting1
DB00209TrospiumNot AvailableCompleted2
DB00209TrospiumNot AvailableUnknown Status1